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Apellis Pharmaceuticals Inc stock is traded at $40.87, with a volume of 4.74M. It is up +0.10% in the last 24 hours and up +115.57% over the past month. Apellis Pharmaceuticals Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system, which is an integral component of the immune system, at the level of C3, the central protein in the complement cascade. Currently it has two marketed drugs that target C3, the central protein in the complement cascade: SYFOVRE (pegcetacoplan injection) and EMPAVELI (pegcetacoplan).
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Previous Close:
$40.79
Open:
$40.73
24h Volume:
4.74M
Relative Volume:
0.96
Market Cap:
$5.22B
Revenue:
$1.00B
Net Income/Loss:
$22.39M
P/E Ratio:
330.89
EPS:
0.1235
Net Cash Flow:
$45.01M
1W Performance:
+0.49%
1M Performance:
+115.57%
6M Performance:
+69.13%
1Y Performance:
+110.24%
1-Day Range:
Value
$40.70
$40.87
1-Week Range:
Value
$40.60
$40.85
52-Week Range:
Value
$16.10
$40.85

Apellis Pharmaceuticals Inc Stock (APLS) Company Profile

Name
Name
Apellis Pharmaceuticals Inc
Name
Phone
617-977-5700
Name
Address
100 FIFTH AVENUE, WALTHAM, KY
Name
Employee
733
Name
Twitter
@ApellisPharma
Name
Next Earnings Date
2024-12-05
Name
Latest SEC Filings
Name
APLS's Discussions on Twitter

Compare APLS vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
APLS icon
APLS
Apellis Pharmaceuticals Inc
40.87 5.21B 1.00B 22.39M 45.01M 0.1235
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
440.40 110.97B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
742.49 79.17B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
809.48 49.73B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
332.95 42.98B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
305.10 34.37B 5.36B 287.73M 924.18M 2.5229

Apellis Pharmaceuticals Inc Stock (APLS) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-13-26 Initiated Roth Capital Buy
Jan-28-26 Initiated Barclays Equal Weight
Jan-21-26 Upgrade BofA Securities Neutral → Buy
Nov-06-25 Initiated Wolfe Research Peer Perform
Oct-15-25 Initiated Wells Fargo Overweight
Sep-26-25 Downgrade Goldman Neutral → Sell
May-09-25 Downgrade BofA Securities Buy → Neutral
May-09-25 Downgrade Raymond James Strong Buy → Outperform
Apr-29-25 Initiated Cantor Fitzgerald Overweight
Dec-17-24 Downgrade Goldman Buy → Neutral
Nov-21-24 Initiated Morgan Stanley Equal-Weight
Oct-25-24 Initiated RBC Capital Mkts Sector Perform
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-16-24 Initiated William Blair Outperform
May-31-24 Initiated Piper Sandler Neutral
Feb-05-24 Upgrade Jefferies Hold → Buy
Dec-14-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-09-23 Initiated Goldman Buy
Nov-02-23 Initiated Mizuho Neutral
Oct-06-23 Upgrade JP Morgan Neutral → Overweight
Sep-15-23 Upgrade Wells Fargo Equal Weight → Overweight
Aug-29-23 Reiterated Citigroup Buy
Aug-03-23 Downgrade JP Morgan Overweight → Neutral
Aug-01-23 Downgrade BofA Securities Buy → Neutral
Jan-03-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-10-22 Downgrade Jefferies Buy → Hold
Jul-19-22 Initiated H.C. Wainwright Buy
Jun-17-22 Resumed Stifel Buy
Apr-14-22 Downgrade ROTH Capital Neutral → Sell
Dec-08-21 Initiated Wells Fargo Overweight
Nov-29-21 Downgrade ROTH Capital Buy → Neutral
Sep-10-21 Reiterated BMO Capital Markets Outperform
Sep-10-21 Reiterated Credit Suisse Neutral
Sep-10-21 Reiterated Needham Buy
Sep-10-21 Reiterated Oppenheimer Outperform
Sep-10-21 Downgrade Wedbush Outperform → Neutral
Aug-19-21 Initiated Jefferies Buy
Aug-19-21 Upgrade Wedbush Neutral → Outperform
May-21-21 Initiated UBS Buy
Apr-16-21 Initiated Goldman Buy
Nov-19-20 Initiated Needham Buy
Sep-01-20 Initiated Stifel Buy
Jul-20-20 Initiated ROTH Capital Buy
Jun-17-20 Initiated BTIG Research Neutral
Apr-01-20 Initiated Raymond James Strong Buy
Mar-31-20 Initiated BMO Capital Markets Outperform
Mar-11-20 Upgrade Wedbush Underperform → Neutral
Jan-07-20 Initiated SVB Leerink Mkt Perform
Dec-19-19 Initiated BofA/Merrill Buy
Nov-22-19 Initiated Wedbush Underperform
Nov-05-19 Initiated Credit Suisse Neutral
Aug-01-19 Reiterated Cantor Fitzgerald Overweight
Jul-12-19 Upgrade JP Morgan Neutral → Overweight
Mar-29-19 Initiated Robert W. Baird Outperform
Jan-23-19 Downgrade JP Morgan Overweight → Neutral
Jul-30-18 Upgrade B. Riley FBR Neutral → Buy
May-24-18 Initiated Cantor Fitzgerald Overweight
Apr-12-18 Downgrade B. Riley FBR, Inc. Buy → Neutral
Feb-08-18 Initiated B. Riley FBR, Inc. Buy
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Apellis Pharmaceuticals Inc Stock (APLS) Latest News

pulisher
09:34 AM

Apellis Pharmaceuticals (APLS) hits 2-year high on 140% upside from Biogen merger - MSN

09:34 AM
pulisher
Apr 12, 2026

Biogen to acquire Apellis for $5.6B to strengthen immunology portfolio - MSN

Apr 12, 2026
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Apr 11, 2026

Valuation Update: Does Apellis Pharmaceuticals Inc stock have upside surprise potential - baoquankhu1.vn

Apr 11, 2026
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Apr 11, 2026

Biogen lands two fast-growing drugs in blockbuster Apellis deal - MSN

Apr 11, 2026
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Apr 10, 2026

Are APLS, CNTA, KZR Obtaining Fair Deals for their Shareholders? - Sahm

Apr 10, 2026
pulisher
Apr 09, 2026

US Market Recap: Will Apellis Pharmaceuticals Inc benefit from geopolitical trendsQuarterly Portfolio Report & High Return Trade Guides - baoquankhu1.vn

Apr 09, 2026
pulisher
Apr 08, 2026

Apellis (APLS) director shifts 5,750 trust shares to spouse account - Stock Titan

Apr 08, 2026
pulisher
Apr 08, 2026

Apellis Stock More Than Doubles on Biogen News. Here’s What to Know. - Barron's

Apr 08, 2026
pulisher
Apr 08, 2026

Trading the Move, Not the Narrative: (APLS) Edition - Stock Traders Daily

Apr 08, 2026
pulisher
Apr 08, 2026

Biogen’s Apellis Deal And High Dose SPINRAZA Shift Growth Outlook - Sahm

Apr 08, 2026
pulisher
Apr 08, 2026

Are APLS, KORE, CNTA Obtaining Fair Deals for their Shareholders? - Sahm

Apr 08, 2026
pulisher
Apr 08, 2026

Apellis Pharmaceuticals Stock Rockets 140% With 6-Day Winning Streak - Trefis

Apr 08, 2026
pulisher
Apr 08, 2026

6-Day Rally Sends Apellis Pharmaceuticals Stock Up 140% - Trefis

Apr 08, 2026
pulisher
Apr 07, 2026

Apellis Pharmaceuticals stock reaches 52-week high at $40.71 By Investing.com - Investing.com Australia

Apr 07, 2026
pulisher
Apr 07, 2026

Biogen (NASDAQ: APLS) readies tender offer for Apellis under March 31, 2026 deal - Stock Titan

Apr 07, 2026
pulisher
Apr 07, 2026

Apellis Pharmaceuticals stock reaches 52-week high at $40.71 - Investing.com

Apr 07, 2026
pulisher
Apr 07, 2026

Retail Surge: Can Apellis Pharmaceuticals Inc grow without dilution2026 Retail & Community Consensus Stock Picks - baoquankhu1.vn

Apr 07, 2026
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Apr 07, 2026

RBC Adjusts Price Target on Apellis Pharmaceuticals to $41 From $21, Maintains Sector Perform Rating - marketscreener.com

Apr 07, 2026
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Apr 07, 2026

Biogen Taps Alloy Platform To Push Antisense Drug Pipeline Forward - Benzinga

Apr 07, 2026
pulisher
Apr 07, 2026

Apellis Pharmaceuticals Acquisition Under Investigation - National Today

Apr 07, 2026
pulisher
Apr 07, 2026

Wellington files 13G/A owning 249,635 shares of Apellis (APLS) - Stock Titan

Apr 07, 2026
pulisher
Apr 07, 2026

Shareholder Alert: Ademi LLP investigates whether Apellis Pharmaceuticals Inc. is obtaining a ... - Bluefield Daily Telegraph

Apr 07, 2026
pulisher
Apr 07, 2026

Shareholder Alert: Ademi LLP investigates whether Apellis - GlobeNewswire

Apr 07, 2026
pulisher
Apr 07, 2026

5-Day Rally Sends Apellis Pharmaceuticals Stock Up 139% - Trefis

Apr 07, 2026
pulisher
Apr 07, 2026

Apellis Pharmaceuticals Stock Surges 139%, With A 5-Day Winning Spree - Trefis

Apr 07, 2026
pulisher
Apr 06, 2026

Biogen (NASDAQ: APLS) files Form 3 on Apellis voting group status - Stock Titan

Apr 06, 2026
pulisher
Apr 06, 2026

Biogen Discloses Tender Offer at Apellis with 14.2% Stake - TradingView — Track All Markets

Apr 06, 2026
pulisher
Apr 06, 2026

[SCHEDULE 13D] Apellis Pharmaceuticals, Inc. Major Shareholder Acquisition (>5%) - Stock Titan

Apr 06, 2026
pulisher
Apr 06, 2026

Biogen Acquires Apellis Pharmaceuticals in $5.6 Billion Move into Immunology - FinancialContent

Apr 06, 2026
pulisher
Apr 06, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Reaches New 12-Month HighWhat's Next? - MarketBeat

Apr 06, 2026
pulisher
Apr 06, 2026

Biogen Paid a 140% Premium for Apellis. Was the $5.6B Deal Worth It? - TIKR.com

Apr 06, 2026
pulisher
Apr 06, 2026

Apellis Stock Soars After Biogen Deal, Momentum Score Surges—Here's What Shareholders Get - Benzinga

Apr 06, 2026
pulisher
Apr 06, 2026

Apellis Pharmaceuticals, Centessa Pharmaceuticals, Agios Pharmaceuticals and other big stocks moving higher on Tuesday - MSN

Apr 06, 2026
pulisher
Apr 06, 2026

Apellis Pharmaceuticals, Inc. (APLS) Stock Price, News, Quote & History - Yahoo! Finance Canada

Apr 06, 2026
pulisher
Apr 04, 2026

Apellis surges on $5.6B buyout deal with Biogen - MSN

Apr 04, 2026
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Apr 04, 2026

Biogen’s Apellis Deal Reshapes Growth Outlook And Valuation Story - Yahoo Finance

Apr 04, 2026
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Apr 04, 2026

TD Cowen Maintains Apellis Pharmaceuticals (APLS) Buy Recommendation - MSN

Apr 04, 2026
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Apr 04, 2026

APLS PE Ratio & Valuation, Is APLS Overvalued - Intellectia AI

Apr 04, 2026
pulisher
Apr 04, 2026

Biogen Bets Big on Kidney Drugs with USD 5.6 Billion Apellis Pharmaceuticals Deal - Medical Dialogues

Apr 04, 2026
pulisher
Apr 03, 2026

Biogen (NASDAQ: BIIB) plans tender offer to acquire Apellis (APLS); materials pending - Stock Titan

Apr 03, 2026
pulisher
Apr 03, 2026

Deal Dispatch: McCormick, Unilever Merge, Sysco Acquires Jetro Restaurant Depot For $29 Billion, QVC Considers Bankruptcy - Benzinga

Apr 03, 2026
pulisher
Apr 03, 2026

Biogen to acquire Apellis in $5.6 billion deal - Ophthalmology Times

Apr 03, 2026
pulisher
Apr 03, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Downgraded by Roth Mkm to "Hold" - marketbeat.com

Apr 03, 2026
pulisher
Apr 03, 2026

Comparing Apellis Pharmaceuticals With Industry Competitors In Biotechnology Industry - Sahm

Apr 03, 2026
pulisher
Apr 02, 2026

APLS Stock Soars 140% Today – Here’s Everything To Know About Apellis' Massive $5.6B Deal With Biogen - Stocktwits

Apr 02, 2026
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Apr 02, 2026

Biogen’s $5.6 Billion Apellis Buy Drives Top Trading Volume Amid Share Price Slide - Bitget

Apr 02, 2026
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Apr 02, 2026

Why Biogen Is Paying $5.6B to Buy Apellis Pharma - MedCity News

Apr 02, 2026
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Apr 02, 2026

Apellis Pharmaceuticals (APLS): Mizuho Raises Price Target Amids - GuruFocus

Apr 02, 2026
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Apr 02, 2026

Mizuho Increases Apellis Pharmaceuticals (NASDAQ:APLS) Price Target to $41.00 - MarketBeat

Apr 02, 2026
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Apr 02, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Downgraded to "Hold" Rating by Jefferies Financial Group - MarketBeat

Apr 02, 2026
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Apr 02, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Downgraded to Hold Rating by Cantor Fitzgerald - MarketBeat

Apr 02, 2026

Apellis Pharmaceuticals Inc Stock (APLS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$28.45
price up icon 0.62%
$48.05
price up icon 0.08%
$96.33
price up icon 0.91%
$131.21
price up icon 36.10%
$155.51
price up icon 0.17%
ONC ONC
$310.52
price up icon 0.28%
Cap:     |  Volume (24h):