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Apellis Pharmaceuticals Inc stock is traded at $24.41, with a volume of 720.62K. It is up +2.63% in the last 24 hours and up +28.45% over the past month. Apellis Pharmaceuticals Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system, which is an integral component of the immune system, at the level of C3, the central protein in the complement cascade.
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Previous Close:
$23.78
Open:
$23.85
24h Volume:
720.62K
Relative Volume:
0.28
Market Cap:
$3.09B
Revenue:
$715.22M
Net Income/Loss:
$-250.10M
P/E Ratio:
-12.03
EPS:
-2.03
Net Cash Flow:
$-205.58M
1W Performance:
+14.85%
1M Performance:
+28.45%
6M Performance:
+24.65%
1Y Performance:
-29.54%
1-Day Range:
Value
$23.69
$24.45
1-Week Range:
Value
$21.16
$24.45
52-Week Range:
Value
$16.10
$35.70

Apellis Pharmaceuticals Inc Stock (APLS) Company Profile

Name
Name
Apellis Pharmaceuticals Inc
Name
Phone
617-977-5700
Name
Address
100 FIFTH AVENUE, WALTHAM, KY
Name
Employee
710
Name
Twitter
@ApellisPharma
Name
Next Earnings Date
2024-12-05
Name
Latest SEC Filings
Name
APLS's Discussions on Twitter

Compare APLS with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
APLS
Apellis Pharmaceuticals Inc
24.42 3.01B 715.22M -250.10M -205.58M -2.03
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
443.81 110.88B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
720.34 72.79B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
893.14 54.76B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
405.61 54.85B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
INSM
Insmed Inc
192.17 41.41B 447.02M -1.18B -906.14M -6.1812

Apellis Pharmaceuticals Inc Stock (APLS) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-06-25 Initiated Wolfe Research Peer Perform
Oct-15-25 Initiated Wells Fargo Overweight
Sep-26-25 Downgrade Goldman Neutral → Sell
May-09-25 Downgrade BofA Securities Buy → Neutral
May-09-25 Downgrade Raymond James Strong Buy → Outperform
Apr-29-25 Initiated Cantor Fitzgerald Overweight
Dec-17-24 Downgrade Goldman Buy → Neutral
Nov-21-24 Initiated Morgan Stanley Equal-Weight
Oct-25-24 Initiated RBC Capital Mkts Sector Perform
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-16-24 Initiated William Blair Outperform
May-31-24 Initiated Piper Sandler Neutral
Feb-05-24 Upgrade Jefferies Hold → Buy
Dec-14-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-09-23 Initiated Goldman Buy
Nov-02-23 Initiated Mizuho Neutral
Oct-06-23 Upgrade JP Morgan Neutral → Overweight
Sep-15-23 Upgrade Wells Fargo Equal Weight → Overweight
Aug-29-23 Reiterated Citigroup Buy
Aug-03-23 Downgrade JP Morgan Overweight → Neutral
Aug-01-23 Downgrade BofA Securities Buy → Neutral
Jan-03-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-10-22 Downgrade Jefferies Buy → Hold
Jul-19-22 Initiated H.C. Wainwright Buy
Jun-17-22 Resumed Stifel Buy
Apr-14-22 Downgrade ROTH Capital Neutral → Sell
Dec-08-21 Initiated Wells Fargo Overweight
Nov-29-21 Downgrade ROTH Capital Buy → Neutral
Sep-10-21 Reiterated BMO Capital Markets Outperform
Sep-10-21 Reiterated Credit Suisse Neutral
Sep-10-21 Reiterated Needham Buy
Sep-10-21 Reiterated Oppenheimer Outperform
Sep-10-21 Downgrade Wedbush Outperform → Neutral
Aug-19-21 Initiated Jefferies Buy
Aug-19-21 Upgrade Wedbush Neutral → Outperform
May-21-21 Initiated UBS Buy
Apr-16-21 Initiated Goldman Buy
Nov-19-20 Initiated Needham Buy
Sep-01-20 Initiated Stifel Buy
Jul-20-20 Initiated ROTH Capital Buy
Jun-17-20 Initiated BTIG Research Neutral
Apr-01-20 Initiated Raymond James Strong Buy
Mar-31-20 Initiated BMO Capital Markets Outperform
Mar-11-20 Upgrade Wedbush Underperform → Neutral
Jan-07-20 Initiated SVB Leerink Mkt Perform
Dec-19-19 Initiated BofA/Merrill Buy
Nov-22-19 Initiated Wedbush Underperform
Nov-05-19 Initiated Credit Suisse Neutral
Aug-01-19 Reiterated Cantor Fitzgerald Overweight
Jul-12-19 Upgrade JP Morgan Neutral → Overweight
Mar-29-19 Initiated Robert W. Baird Outperform
Jan-23-19 Downgrade JP Morgan Overweight → Neutral
Jul-30-18 Upgrade B. Riley FBR Neutral → Buy
May-24-18 Initiated Cantor Fitzgerald Overweight
Apr-12-18 Downgrade B. Riley FBR, Inc. Buy → Neutral
Feb-08-18 Initiated B. Riley FBR, Inc. Buy
View All

Apellis Pharmaceuticals Inc Stock (APLS) Latest News

pulisher
04:57 AM

Mizuho Lowers Price Target on Apellis Pharmaceuticals (APLS) Amid Ongoing Eye Disease Therapy Challenges - MSN

04:57 AM
pulisher
Dec 09, 2025

Jump Financial LLC Buys 293,075 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 09, 2025
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Dec 07, 2025

Technical Reactions to APLS Trends in Macro Strategies - news.stocktradersdaily.com

Dec 07, 2025
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Dec 07, 2025

Marshall Wace LLP Buys 2,681,263 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 07, 2025
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Dec 07, 2025

Norges Bank Takes Position in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 07, 2025
pulisher
Dec 07, 2025

Apellis Pharmaceuticals (APLS) Surges 17.6% on Higher Price Target - MSN

Dec 07, 2025
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Dec 06, 2025

Apellis Pharmaceuticals (NASDAQ:APLS) Stock Price Up 6.2%Still a Buy? - MarketBeat

Dec 06, 2025
pulisher
Dec 06, 2025

Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) Given Average Rating of "Hold" by Analysts - MarketBeat

Dec 06, 2025
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Dec 05, 2025

Apellis Pharmaceuticals (APLS): Valuation Check After Positive EMPAVELI Kidney Data and New FDA Approval - Yahoo Finance

Dec 05, 2025
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Dec 05, 2025

Schroder Investment Management Group Grows Position in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 05, 2025
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Dec 04, 2025

What downside risks could hit Apellis Pharmaceuticals Inc. (1JK) stockRecession Risk & AI Optimized Trade Strategies - Newser

Dec 04, 2025
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Dec 04, 2025

Why millennials buy Apellis Pharmaceuticals Inc. (1JK) stockPrice Action & High Accuracy Trade Alerts - Newser

Dec 04, 2025
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Dec 04, 2025

Prudential Financial Inc. Decreases Stock Holdings in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 04, 2025
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Dec 04, 2025

Will Apellis Pharmaceuticals Inc. (1JK) stock issue positive guidanceJobs Report & Fast Entry Momentum Trade Alerts - Newser

Dec 04, 2025
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Dec 04, 2025

Why Apellis Pharmaceuticals Inc. (1JK) stock gets analyst attentionRate Cut & High Conviction Buy Zone Picks - Newser

Dec 04, 2025
pulisher
Dec 03, 2025

Apellis’ EMPAVELI shows 68% reduction in proteinuria for rare kidney diseases - Investing.com Nigeria

Dec 03, 2025
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Dec 03, 2025

Apellis Reports Positive Phase 3 Results for Its Kidney Disease Treatment Empaveli - marketscreener.com

Dec 03, 2025
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Dec 03, 2025

Apellis (APLS) Gains Boost from Positive Phase 3 Study Results - GuruFocus

Dec 03, 2025
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Dec 03, 2025

Apellis Pharmaceuticals Announces Positive Phase 3 VALIANT Study Results for EMPAVELI in Treating C3 Glomerulopathy and Primary IC-MPGN - Quiver Quantitative

Dec 03, 2025
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Dec 03, 2025

Transcript : Apellis Pharmaceuticals, Inc. Presents at Evercore 8th Annual Healthcare Conference, Dec-03-2025 02 - marketscreener.com

Dec 03, 2025
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Dec 03, 2025

Why Apellis Pharmaceuticals Inc. (1JK) stock could rally stronglyMarket Performance Summary & AI Powered Market Entry Ideas - Newser

Dec 03, 2025
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Dec 03, 2025

Why Apellis Pharmaceuticals Inc. (1JK) stock could be top winnerJuly 2025 Summary & High Yield Equity Trading Tips - Newser

Dec 03, 2025
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Dec 02, 2025

38,572 Shares in Apellis Pharmaceuticals, Inc. $APLS Purchased by Wealthedge Investment Advisors LLC - MarketBeat

Dec 02, 2025
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Dec 02, 2025

Will Apellis Pharmaceuticals Inc. stock deliver long term returnsAnalyst Upgrade & Growth Oriented Trading Recommendations - Newser

Dec 02, 2025
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Dec 01, 2025

Geographic Atrophy Market to Surge Significantly During the Forecast Period (2025–2034) Due to Rising Adoption of Complement Inhibitor Therapies | DelveInsight - GlobeNewswire Inc.

Dec 01, 2025
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Dec 01, 2025

Virtus Investment Advisers LLC Acquires 12,106 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 01, 2025
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Nov 30, 2025

Steward Partners Investment Advisory LLC Buys 18,800 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Nov 30, 2025
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Nov 30, 2025

Apellis Post Hoc Analysis Confirms Long-Term Benefit of SYFOVRE for Geographic Atrophy - MSN

Nov 30, 2025
pulisher
Nov 28, 2025

Geode Capital Management LLC Raises Stake in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Nov 28, 2025
pulisher
Nov 27, 2025

Breakout Watch: How risky is Apellis Pharmaceuticals Inc. (1JK) stock compared to peers2025 Valuation Update & Weekly Sector Rotation Insights - BỘ NỘI VỤ

Nov 27, 2025
pulisher
Nov 27, 2025

Apellis Pharmaceuticals, Inc. $APLS Position Increased by Rhenman & Partners Asset Management AB - MarketBeat

Nov 27, 2025
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Nov 26, 2025

Apellis Pharmaceuticals (APLS) Stock Price Prediction: Today, Tomorrow, Next Week - Traders Union

Nov 26, 2025
pulisher
Nov 26, 2025

Trading the Move, Not the Narrative: (APLS) Edition - news.stocktradersdaily.com

Nov 26, 2025
pulisher
Nov 26, 2025

Can Sanmitra Commercial Limited Maintain Its Strong Profit MarginsInterest Rate Changes & High Yield Investment Portfolio - earlytimes.in

Nov 26, 2025
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Nov 26, 2025

Apellis Pharmaceuticals, Inc. $APLS Stock Position Decreased by SG Americas Securities LLC - MarketBeat

Nov 26, 2025
pulisher
Nov 25, 2025

Apellis Pharmaceuticals to Participate in Upcoming Investor Conferences - The Manila Times

Nov 25, 2025
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Nov 25, 2025

Apellis Pharmaceuticals (Nasdaq: APLS) to Webcast Investor Chats at 2025 Conferences - Stock Titan

Nov 25, 2025
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Nov 24, 2025

Apellis targets 225 EMPAVELI start forms by year-end amid steady SYFOVRE growth and expanded rare kidney launch - MSN

Nov 24, 2025
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Nov 23, 2025

9 Oversold Biotech Stocks to Invest In - Insider Monkey

Nov 23, 2025
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Nov 22, 2025

FY2025 Earnings Estimate for APLS Issued By Zacks Research - MarketBeat

Nov 22, 2025
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Nov 21, 2025

Can Apellis Pharmaceuticals Inc. stock beat analyst upgradesShare Buyback & AI Powered Market Entry Ideas - newser.com

Nov 21, 2025
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Nov 21, 2025

Will Apellis Pharmaceuticals Inc. stock deliver better than expected guidanceQuarterly Growth Report & Daily Oversold Stock Bounce Ideas - newser.com

Nov 21, 2025
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Nov 20, 2025

Does Apellis Pharmaceuticals Inc. (1JK) stock trade below intrinsic valueQuarterly Investment Review & Safe Entry Momentum Tips - newser.com

Nov 20, 2025
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Nov 20, 2025

Apellis Pharmaceuticals Faces Weak Start with 17.3% Gap Down Amid Market Concerns - Markets Mojo

Nov 20, 2025
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Nov 20, 2025

Why Apellis Pharmaceuticals Inc. (1JK) stock stays on buy listsShare Buyback & Safe Swing Trade Setups - newser.com

Nov 20, 2025
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Nov 20, 2025

Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) Looks Inexpensive After Falling 28% But Perhaps Not Attractive Enough - 富途牛牛

Nov 20, 2025
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Nov 20, 2025

Using AI based signals to follow Apellis Pharmaceuticals Inc.Gold Moves & Free Safe Entry Trade Signal Reports - newser.com

Nov 20, 2025
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Nov 20, 2025

Apellis Pharmaceuticals Inc. stock prediction for this weekPortfolio Value Report & Stepwise Trade Execution Plans - newser.com

Nov 20, 2025

Apellis Pharmaceuticals Inc Stock (APLS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$38.05
price down icon 0.04%
$95.48
price up icon 0.80%
$31.17
price up icon 0.87%
$95.53
price down icon 0.43%
biotechnology ONC
$317.50
price down icon 0.27%
$196.50
price up icon 1.32%
Cap:     |  Volume (24h):