25.16
price up icon1.37%   0.34
after-market After Hours: 25.16
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Apellis Pharmaceuticals Inc stock is traded at $25.16, with a volume of 864.30K. It is up +1.37% in the last 24 hours and up +24.99% over the past month. Apellis Pharmaceuticals Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system, which is an integral component of the immune system, at the level of C3, the central protein in the complement cascade.
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Previous Close:
$24.82
Open:
$24.88
24h Volume:
864.30K
Relative Volume:
0.33
Market Cap:
$3.18B
Revenue:
$715.22M
Net Income/Loss:
$-250.10M
P/E Ratio:
-12.39
EPS:
-2.03
Net Cash Flow:
$-205.58M
1W Performance:
-0.16%
1M Performance:
+24.99%
6M Performance:
+35.20%
1Y Performance:
-24.49%
1-Day Range:
Value
$24.74
$25.20
1-Week Range:
Value
$24.25
$26.12
52-Week Range:
Value
$16.10
$35.57

Apellis Pharmaceuticals Inc Stock (APLS) Company Profile

Name
Name
Apellis Pharmaceuticals Inc
Name
Phone
617-977-5700
Name
Address
100 FIFTH AVENUE, WALTHAM, KY
Name
Employee
710
Name
Twitter
@ApellisPharma
Name
Next Earnings Date
2024-12-05
Name
Latest SEC Filings
Name
APLS's Discussions on Twitter

Compare APLS with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
APLS
Apellis Pharmaceuticals Inc
25.16 3.14B 715.22M -250.10M -205.58M -2.03
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
462.99 116.51B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
783.71 82.52B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
400.69 52.67B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
849.95 52.08B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
177.42 37.70B 447.02M -1.18B -906.14M -6.1812

Apellis Pharmaceuticals Inc Stock (APLS) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-06-25 Initiated Wolfe Research Peer Perform
Oct-15-25 Initiated Wells Fargo Overweight
Sep-26-25 Downgrade Goldman Neutral → Sell
May-09-25 Downgrade BofA Securities Buy → Neutral
May-09-25 Downgrade Raymond James Strong Buy → Outperform
Apr-29-25 Initiated Cantor Fitzgerald Overweight
Dec-17-24 Downgrade Goldman Buy → Neutral
Nov-21-24 Initiated Morgan Stanley Equal-Weight
Oct-25-24 Initiated RBC Capital Mkts Sector Perform
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-16-24 Initiated William Blair Outperform
May-31-24 Initiated Piper Sandler Neutral
Feb-05-24 Upgrade Jefferies Hold → Buy
Dec-14-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-09-23 Initiated Goldman Buy
Nov-02-23 Initiated Mizuho Neutral
Oct-06-23 Upgrade JP Morgan Neutral → Overweight
Sep-15-23 Upgrade Wells Fargo Equal Weight → Overweight
Aug-29-23 Reiterated Citigroup Buy
Aug-03-23 Downgrade JP Morgan Overweight → Neutral
Aug-01-23 Downgrade BofA Securities Buy → Neutral
Jan-03-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-10-22 Downgrade Jefferies Buy → Hold
Jul-19-22 Initiated H.C. Wainwright Buy
Jun-17-22 Resumed Stifel Buy
Apr-14-22 Downgrade ROTH Capital Neutral → Sell
Dec-08-21 Initiated Wells Fargo Overweight
Nov-29-21 Downgrade ROTH Capital Buy → Neutral
Sep-10-21 Reiterated BMO Capital Markets Outperform
Sep-10-21 Reiterated Credit Suisse Neutral
Sep-10-21 Reiterated Needham Buy
Sep-10-21 Reiterated Oppenheimer Outperform
Sep-10-21 Downgrade Wedbush Outperform → Neutral
Aug-19-21 Initiated Jefferies Buy
Aug-19-21 Upgrade Wedbush Neutral → Outperform
May-21-21 Initiated UBS Buy
Apr-16-21 Initiated Goldman Buy
Nov-19-20 Initiated Needham Buy
Sep-01-20 Initiated Stifel Buy
Jul-20-20 Initiated ROTH Capital Buy
Jun-17-20 Initiated BTIG Research Neutral
Apr-01-20 Initiated Raymond James Strong Buy
Mar-31-20 Initiated BMO Capital Markets Outperform
Mar-11-20 Upgrade Wedbush Underperform → Neutral
Jan-07-20 Initiated SVB Leerink Mkt Perform
Dec-19-19 Initiated BofA/Merrill Buy
Nov-22-19 Initiated Wedbush Underperform
Nov-05-19 Initiated Credit Suisse Neutral
Aug-01-19 Reiterated Cantor Fitzgerald Overweight
Jul-12-19 Upgrade JP Morgan Neutral → Overweight
Mar-29-19 Initiated Robert W. Baird Outperform
Jan-23-19 Downgrade JP Morgan Overweight → Neutral
Jul-30-18 Upgrade B. Riley FBR Neutral → Buy
May-24-18 Initiated Cantor Fitzgerald Overweight
Apr-12-18 Downgrade B. Riley FBR, Inc. Buy → Neutral
Feb-08-18 Initiated B. Riley FBR, Inc. Buy
View All

Apellis Pharmaceuticals Inc Stock (APLS) Latest News

pulisher
Dec 23, 2025

How sustainable is Apellis Pharmaceuticals Inc. stock dividend payoutInstitutional Buying Trends & Affordable Investment Portfolio - Bollywood Helpline

Dec 23, 2025
pulisher
Dec 23, 2025

Analysts’ Opinions Are Mixed on These Healthcare Stocks: Apellis Pharmaceuticals (APLS) and Argenx Se (ARGX) - The Globe and Mail

Dec 23, 2025
pulisher
Dec 22, 2025

Mizuho Securities Maintains Apellis Pharmaceuticals(APLS.US) With Hold Rating - 富途牛牛

Dec 22, 2025
pulisher
Dec 20, 2025

Will Apellis Pharmaceuticals Inc. (1JK) stock outperform foreign stocksEarnings Risk Report & Reliable Volume Spike Trade Alerts - Улправда

Dec 20, 2025
pulisher
Dec 20, 2025

How risky is Apellis Pharmaceuticals Inc. (1JK) stock compared to peers2025 Retail Activity & Free Technical Pattern Based Buy Signals - Улправда

Dec 20, 2025
pulisher
Dec 20, 2025

Why Apellis Pharmaceuticals Inc. stock appeals to dividend seekersWeekly Trade Recap & High Conviction Buy Zone Picks - Улправда

Dec 20, 2025
pulisher
Dec 20, 2025

Will Apellis Pharmaceuticals Inc. stock see PE expansion2025 Trading Recap & Reliable Price Breakout Signals - Улправда

Dec 20, 2025
pulisher
Dec 20, 2025

Stifel maintains Apellis Pharmaceuticals (APLS) buy recommendation - MSN

Dec 20, 2025
pulisher
Dec 19, 2025

APLS (Apellis Pharmaceuticals) EV-to-OCF : 39.23 (As of Dec. 19, 2025) - GuruFocus

Dec 19, 2025
pulisher
Dec 19, 2025

Apellis Pharmaceuticals stock price target lowered to $48 at Stifel By Investing.com - Investing.com Canada

Dec 19, 2025
pulisher
Dec 19, 2025

Stifel Lowers Price Target for Apellis Pharmaceuticals (APLS) to $48 | APLS Stock News - GuruFocus

Dec 19, 2025
pulisher
Dec 19, 2025

Stifel Nicolaus Cuts Apellis Pharmaceuticals (NASDAQ:APLS) Price Target to $48.00 - MarketBeat

Dec 19, 2025
pulisher
Dec 19, 2025

Is Apellis Pharmaceuticals Inc. stock near bottom after decline2025 Pullback Review & AI Forecasted Entry and Exit Points - DonanımHaber

Dec 19, 2025
pulisher
Dec 19, 2025

What technical charts say about Apellis Pharmaceuticals Inc. stock2025 Technical Overview & Comprehensive Market Scan Insights - Улправда

Dec 19, 2025
pulisher
Dec 18, 2025

Insider Selling: Apellis Pharmaceuticals (NASDAQ:APLS) General Counsel Sells 5,000 Shares of Stock - MarketBeat

Dec 18, 2025
pulisher
Dec 18, 2025

Precision Trading with Apellis Pharmaceuticals Inc. (APLS) Risk Zones - Stock Traders Daily

Dec 18, 2025
pulisher
Dec 18, 2025

Officer Watson Sells 5,000 ($122.5K) Of Apellis Pharmaceuticals Inc [APLS] - TradingView — Track All Markets

Dec 18, 2025
pulisher
Dec 18, 2025

[Form 4] Apellis Pharmaceuticals, Inc. Insider Trading Activity - Stock Titan

Dec 18, 2025
pulisher
Dec 16, 2025

Investors in Apellis Pharmaceuticals (NASDAQ:APLS) From Five Years Ago Are Still Down 54%, Even After 3.2% Gain This Past Week - 富途牛牛

Dec 16, 2025
pulisher
Dec 16, 2025

Officer Watson Files To Sell 5,000 Of Apellis Pharmaceuticals Inc [APLS] - TradingView — Track All Markets

Dec 16, 2025
pulisher
Dec 16, 2025

Hudson Bay Capital Management LP Has $8.22 Million Stock Holdings in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 16, 2025
pulisher
Dec 15, 2025

Apellis stock rating reiterated at Outperform by William Blair - Investing.com Canada

Dec 15, 2025
pulisher
Dec 15, 2025

Squarepoint Ops LLC Cuts Stock Holdings in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 15, 2025
pulisher
Dec 13, 2025

Braidwell LP Sells 531,300 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 13, 2025
pulisher
Dec 13, 2025

683 Capital Management LLC Buys 77,000 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 13, 2025
pulisher
Dec 12, 2025

Apellis Pharmaceuticals: A Good Product That Just Misses The Mark (NASDAQ:APLS) - Seeking Alpha

Dec 12, 2025
pulisher
Dec 12, 2025

Natixis Sells 564,361 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 12, 2025
pulisher
Dec 12, 2025

Camber Capital Management LP Acquires New Holdings in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 12, 2025
pulisher
Dec 11, 2025

Bank of Nova Scotia Makes New Investment in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 11, 2025
pulisher
Dec 10, 2025

Apellis Pharmaceuticals Inc Stock Analysis and ForecastRetail Trading Trends & Low Cost Wealth Building - earlytimes.in

Dec 10, 2025
pulisher
Dec 10, 2025

Mizuho Lowers Price Target on Apellis Pharmaceuticals (APLS) Amid Ongoing Eye Disease Therapy Challenges - MSN

Dec 10, 2025
pulisher
Dec 10, 2025

Apellis Pharmaceuticals, Inc. $APLS Shares Purchased by Amundi - MarketBeat

Dec 10, 2025
pulisher
Dec 09, 2025

Jump Financial LLC Buys 293,075 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 09, 2025
pulisher
Dec 08, 2025

Would You Still Hold Apellis Pharmaceuticals Stock If It Fell 30%? - Trefis

Dec 08, 2025
pulisher
Dec 07, 2025

Technical Reactions to APLS Trends in Macro Strategies - news.stocktradersdaily.com

Dec 07, 2025
pulisher
Dec 07, 2025

Marshall Wace LLP Buys 2,681,263 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 07, 2025
pulisher
Dec 07, 2025

Norges Bank Takes Position in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 07, 2025
pulisher
Dec 07, 2025

Apellis Pharmaceuticals (APLS) Surges 17.6% on Higher Price Target - MSN

Dec 07, 2025
pulisher
Dec 06, 2025

Apellis Post Hoc Analysis Confirms Long-Term Benefit of SYFOVRE for Geographic Atrophy - MSN

Dec 06, 2025
pulisher
Dec 06, 2025

Apellis Pharmaceuticals (NASDAQ:APLS) Stock Price Up 6.2%Still a Buy? - MarketBeat

Dec 06, 2025
pulisher
Dec 06, 2025

Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) Given Average Rating of "Hold" by Analysts - MarketBeat

Dec 06, 2025
pulisher
Dec 05, 2025

Apellis Pharmaceuticals (APLS): Valuation Check After Positive EMPAVELI Kidney Data and New FDA Approval - Yahoo Finance

Dec 05, 2025
pulisher
Dec 05, 2025

Schroder Investment Management Group Grows Position in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 05, 2025
pulisher
Dec 04, 2025

What downside risks could hit Apellis Pharmaceuticals Inc. (1JK) stockRecession Risk & AI Optimized Trade Strategies - Newser

Dec 04, 2025
pulisher
Dec 04, 2025

Why millennials buy Apellis Pharmaceuticals Inc. (1JK) stockPrice Action & High Accuracy Trade Alerts - Newser

Dec 04, 2025
pulisher
Dec 04, 2025

Prudential Financial Inc. Decreases Stock Holdings in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Dec 04, 2025
pulisher
Dec 04, 2025

Will Apellis Pharmaceuticals Inc. (1JK) stock issue positive guidanceJobs Report & Fast Entry Momentum Trade Alerts - Newser

Dec 04, 2025
pulisher
Dec 04, 2025

Why Apellis Pharmaceuticals Inc. (1JK) stock gets analyst attentionRate Cut & High Conviction Buy Zone Picks - Newser

Dec 04, 2025
pulisher
Dec 03, 2025

Apellis’ EMPAVELI shows 68% reduction in proteinuria for rare kidney diseases - Investing.com Nigeria

Dec 03, 2025
pulisher
Dec 03, 2025

Apellis Reports Positive Phase 3 Results for Its Kidney Disease Treatment Empaveli - marketscreener.com

Dec 03, 2025
pulisher
Dec 03, 2025

Apellis (APLS) Gains Boost from Positive Phase 3 Study Results - GuruFocus

Dec 03, 2025

Apellis Pharmaceuticals Inc Stock (APLS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$39.25
price down icon 0.36%
$100.44
price down icon 0.47%
$33.72
price up icon 0.21%
$95.03
price up icon 0.95%
biotechnology ONC
$311.73
price down icon 0.19%
$177.42
price up icon 0.37%
Cap:     |  Volume (24h):