40.94
price up icon0.05%   0.04
after-market After Hours: 40.89 -0.05 -0.12%
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Apellis Pharmaceuticals Inc stock is traded at $40.94, with a volume of 4.11M. It is up +0.05% in the last 24 hours and up +137.77% over the past month. Apellis Pharmaceuticals Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system, which is an integral component of the immune system, at the level of C3, the central protein in the complement cascade. Currently it has two marketed drugs that target C3, the central protein in the complement cascade: SYFOVRE (pegcetacoplan injection) and EMPAVELI (pegcetacoplan).
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Previous Close:
$40.90
Open:
$40.88
24h Volume:
4.11M
Relative Volume:
0.82
Market Cap:
$5.23B
Revenue:
$1.00B
Net Income/Loss:
$22.39M
P/E Ratio:
331.50
EPS:
0.1235
Net Cash Flow:
$45.01M
1W Performance:
+0.20%
1M Performance:
+137.77%
6M Performance:
+51.16%
1Y Performance:
+124.84%
1-Day Range:
Value
$40.86
$40.94
1-Week Range:
Value
$40.78
$40.95
52-Week Range:
Value
$16.10
$40.95

Apellis Pharmaceuticals Inc Stock (APLS) Company Profile

Name
Name
Apellis Pharmaceuticals Inc
Name
Phone
617-977-5700
Name
Address
100 FIFTH AVENUE, WALTHAM, KY
Name
Employee
733
Name
Twitter
@ApellisPharma
Name
Next Earnings Date
2026-05-06
Name
Latest SEC Filings
Name
APLS's Discussions on Twitter

Compare APLS vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
APLS icon
APLS
Apellis Pharmaceuticals Inc
40.94 5.23B 1.00B 22.39M 45.01M 0.1235
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
439.18 112.22B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
749.41 79.35B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
834.45 52.80B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
310.94 41.32B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
318.07 35.95B 5.36B 287.73M 924.18M 2.5229

Apellis Pharmaceuticals Inc Stock (APLS) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-13-26 Initiated Roth Capital Buy
Jan-28-26 Initiated Barclays Equal Weight
Jan-21-26 Upgrade BofA Securities Neutral → Buy
Nov-06-25 Initiated Wolfe Research Peer Perform
Oct-15-25 Initiated Wells Fargo Overweight
Sep-26-25 Downgrade Goldman Neutral → Sell
May-09-25 Downgrade BofA Securities Buy → Neutral
May-09-25 Downgrade Raymond James Strong Buy → Outperform
Apr-29-25 Initiated Cantor Fitzgerald Overweight
Dec-17-24 Downgrade Goldman Buy → Neutral
Nov-21-24 Initiated Morgan Stanley Equal-Weight
Oct-25-24 Initiated RBC Capital Mkts Sector Perform
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-16-24 Initiated William Blair Outperform
May-31-24 Initiated Piper Sandler Neutral
Feb-05-24 Upgrade Jefferies Hold → Buy
Dec-14-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-09-23 Initiated Goldman Buy
Nov-02-23 Initiated Mizuho Neutral
Oct-06-23 Upgrade JP Morgan Neutral → Overweight
Sep-15-23 Upgrade Wells Fargo Equal Weight → Overweight
Aug-29-23 Reiterated Citigroup Buy
Aug-03-23 Downgrade JP Morgan Overweight → Neutral
Aug-01-23 Downgrade BofA Securities Buy → Neutral
Jan-03-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-10-22 Downgrade Jefferies Buy → Hold
Jul-19-22 Initiated H.C. Wainwright Buy
Jun-17-22 Resumed Stifel Buy
Apr-14-22 Downgrade ROTH Capital Neutral → Sell
Dec-08-21 Initiated Wells Fargo Overweight
Nov-29-21 Downgrade ROTH Capital Buy → Neutral
Sep-10-21 Reiterated BMO Capital Markets Outperform
Sep-10-21 Reiterated Credit Suisse Neutral
Sep-10-21 Reiterated Needham Buy
Sep-10-21 Reiterated Oppenheimer Outperform
Sep-10-21 Downgrade Wedbush Outperform → Neutral
Aug-19-21 Initiated Jefferies Buy
Aug-19-21 Upgrade Wedbush Neutral → Outperform
May-21-21 Initiated UBS Buy
Apr-16-21 Initiated Goldman Buy
Nov-19-20 Initiated Needham Buy
Sep-01-20 Initiated Stifel Buy
Jul-20-20 Initiated ROTH Capital Buy
Jun-17-20 Initiated BTIG Research Neutral
Apr-01-20 Initiated Raymond James Strong Buy
Mar-31-20 Initiated BMO Capital Markets Outperform
Mar-11-20 Upgrade Wedbush Underperform → Neutral
Jan-07-20 Initiated SVB Leerink Mkt Perform
Dec-19-19 Initiated BofA/Merrill Buy
Nov-22-19 Initiated Wedbush Underperform
Nov-05-19 Initiated Credit Suisse Neutral
Aug-01-19 Reiterated Cantor Fitzgerald Overweight
Jul-12-19 Upgrade JP Morgan Neutral → Overweight
Mar-29-19 Initiated Robert W. Baird Outperform
Jan-23-19 Downgrade JP Morgan Overweight → Neutral
Jul-30-18 Upgrade B. Riley FBR Neutral → Buy
May-24-18 Initiated Cantor Fitzgerald Overweight
Apr-12-18 Downgrade B. Riley FBR, Inc. Buy → Neutral
Feb-08-18 Initiated B. Riley FBR, Inc. Buy
View All

Apellis Pharmaceuticals Inc Stock (APLS) Latest News

pulisher
01:44 AM

Apellis Pharmaceuticals (APLS) Tops Overbought Healthcare Stocks List - GuruFocus

01:44 AM
pulisher
11:55 AM

Apellis Pharmaceuticals is the most overbought healthcare stock as Q1 earnings roll on (XLV:NYSEARCA) - Seeking Alpha

11:55 AM
pulisher
Apr 19, 2026

Biogen raised to overweight at Piper Sandler on Apellis buyout - MSN

Apr 19, 2026
pulisher
Apr 19, 2026

Biogen Expands Targeted Therapy Pipeline With Apellis Deal And Alloy Alliance - Yahoo Finance

Apr 19, 2026
pulisher
Apr 19, 2026

Apellis Pharmaceuticals (APLS) hits 2-year high on 140% upside from Biogen merger - MSN

Apr 19, 2026
pulisher
Apr 19, 2026

Technical Reactions to APLS Trends in Macro Strategies - Stock Traders Daily

Apr 19, 2026
pulisher
Apr 18, 2026

Biogen’s Apellis Deal Reshapes Growth Story And Pipeline Priorities - simplywall.st

Apr 18, 2026
pulisher
Apr 18, 2026

Wells Fargo downgrades Apellis Pharmaceuticals (APLS) - MSN

Apr 18, 2026
pulisher
Apr 18, 2026

Apellis Pharmaceuticals, Inc. (APLS) Surpasses Q4 Earnings and Revenue Estimates - Eastern Progress

Apr 18, 2026
pulisher
Apr 17, 2026

APLS Downgraded by Wells Fargo -- Price Target Raised to $41 - GuruFocus

Apr 17, 2026
pulisher
Apr 17, 2026

Wells Fargo Downgrades Apellis Pharmaceuticals(APLS.US) to Hold Rating, Raises Target Price to $41 - Moomoo

Apr 17, 2026
pulisher
Apr 17, 2026

Apellis (APLS) Receives Downgrade from Wells Fargo with New Pric - GuruFocus

Apr 17, 2026
pulisher
Apr 17, 2026

Apellis Pharmaceuticals' (APLS) Equal Weight Rating Reiterated at Wells Fargo & Company - MarketBeat

Apr 17, 2026
pulisher
Apr 17, 2026

Apellis Pharmaceuticals Inc (NASDAQ:APLS) Emerges as a Growth Stock with Bullish Technical Breakout Potential - ChartMill

Apr 17, 2026
pulisher
Apr 15, 2026

Apellis Pharmaceuticals stock hits 52-week high at 40.87 USD By Investing.com - Investing.com Australia

Apr 15, 2026
pulisher
Apr 15, 2026

Mizuho reiterates Apellis stock rating citing M&A process details - Investing.com

Apr 15, 2026
pulisher
Apr 15, 2026

Mizuho reiterates Apellis stock rating citing M&A process details By Investing.com - Investing.com Canada

Apr 15, 2026
pulisher
Apr 15, 2026

Biogen to acquire Apellis for $5.6B to strengthen immunology portfolio - MSN

Apr 15, 2026
pulisher
Apr 14, 2026

Apellis Pharmaceuticals stock hits 52-week high at 40.87 USD - Investing.com

Apr 14, 2026
pulisher
Apr 14, 2026

M&A Class Action Firm Investigating Multiple Mergers - National Today

Apr 14, 2026
pulisher
Apr 14, 2026

Biogen stock upgraded at Piper Sandler (BIIB:NASDAQ) - Seeking Alpha

Apr 14, 2026
pulisher
Apr 14, 2026

Apellis Pharmaceuticals | SC TO-T: Third party tender offer statement - Moomoo

Apr 14, 2026
pulisher
Apr 14, 2026

Apellis (APLS) board recommends $41 cash takeover by Biogen with up to $4 CVR - Stock Titan

Apr 14, 2026
pulisher
Apr 14, 2026

Biogen (NASDAQ: APLS) bids $41 per share plus up to $4 CVR for Apellis - Stock Titan

Apr 14, 2026
pulisher
Apr 14, 2026

Wellington Management Group LLP Significantly Reduces Stake in Apellis Pharmaceuticals Inc - GuruFocus

Apr 14, 2026
pulisher
Apr 13, 2026

Support Test: Can Apellis Pharmaceuticals Inc stock outperform in a bear marketMarket Weekly Review & Precise Buy Zone Tips - baoquankhu1.vn

Apr 13, 2026
pulisher
Apr 13, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Reaches New 52-Week HighShould You Buy? - MarketBeat

Apr 13, 2026
pulisher
Apr 13, 2026

Apellis Pharmaceuticals, Centessa Pharmaceuticals, Agios Pharmaceuticals and other big stocks moving higher on Tuesday - MSN

Apr 13, 2026
pulisher
Apr 11, 2026

Valuation Update: Does Apellis Pharmaceuticals Inc stock have upside surprise potential - baoquankhu1.vn

Apr 11, 2026
pulisher
Apr 11, 2026

Biogen lands two fast-growing drugs in blockbuster Apellis deal - MSN

Apr 11, 2026
pulisher
Apr 10, 2026

Are APLS, CNTA, KZR Obtaining Fair Deals for their Shareholders? - Finviz

Apr 10, 2026
pulisher
Apr 10, 2026

JPMorgan Chase & Co. Sells 181,285 Shares of Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Apr 10, 2026
pulisher
Apr 10, 2026

Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) Given Average Rating of "Hold" by Analysts - MarketBeat

Apr 10, 2026
pulisher
Apr 09, 2026

Apellis Pharmaceuticals, Inc. $APLS Shares Sold by Wealth Enhancement Advisory Services LLC - MarketBeat

Apr 09, 2026
pulisher
Apr 09, 2026

US Market Recap: Will Apellis Pharmaceuticals Inc benefit from geopolitical trendsQuarterly Portfolio Report & High Return Trade Guides - baoquankhu1.vn

Apr 09, 2026
pulisher
Apr 08, 2026

Apellis (APLS) director shifts 5,750 trust shares to spouse account - Stock Titan

Apr 08, 2026
pulisher
Apr 08, 2026

Apellis Stock More Than Doubles on Biogen News. Here’s What to Know. - Barron's

Apr 08, 2026
pulisher
Apr 08, 2026

Trading the Move, Not the Narrative: (APLS) Edition - Stock Traders Daily

Apr 08, 2026
pulisher
Apr 08, 2026

Biogen’s Apellis Deal And High Dose SPINRAZA Shift Growth Outlook - Sahm

Apr 08, 2026
pulisher
Apr 08, 2026

Are APLS, KORE, CNTA Obtaining Fair Deals for their Shareholders? - Sahm

Apr 08, 2026
pulisher
Apr 08, 2026

Apellis Pharmaceuticals Stock Rockets 140% With 6-Day Winning Streak - Trefis

Apr 08, 2026
pulisher
Apr 08, 2026

6-Day Rally Sends Apellis Pharmaceuticals Stock Up 140% - Trefis

Apr 08, 2026
pulisher
Apr 07, 2026

Apellis Pharmaceuticals stock reaches 52-week high at $40.71 By Investing.com - Investing.com Australia

Apr 07, 2026
pulisher
Apr 07, 2026

Biogen (NASDAQ: APLS) readies tender offer for Apellis under March 31, 2026 deal - Stock Titan

Apr 07, 2026
pulisher
Apr 07, 2026

Apellis Pharmaceuticals stock reaches 52-week high at $40.71 - Investing.com

Apr 07, 2026

Apellis Pharmaceuticals Inc Stock (APLS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$54.59
price up icon 1.62%
$49.30
price down icon 1.49%
$105.19
price up icon 2.19%
$146.23
price down icon 1.51%
$142.82
price down icon 1.09%
ONC ONC
$318.07
price down icon 1.83%
Cap:     |  Volume (24h):