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Apellis Pharmaceuticals Inc stock is traded at $40.63, with a volume of 3.91M. It is up +0.53% in the last 24 hours and up +102.41% over the past month. Apellis Pharmaceuticals Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system, which is an integral component of the immune system, at the level of C3, the central protein in the complement cascade. Currently it has two marketed drugs that target C3, the central protein in the complement cascade: SYFOVRE (pegcetacoplan injection) and EMPAVELI (pegcetacoplan).
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Previous Close:
$40.41
Open:
$40.43
24h Volume:
3.91M
Relative Volume:
0.84
Market Cap:
$5.19B
Revenue:
$1.00B
Net Income/Loss:
$22.39M
P/E Ratio:
328.95
EPS:
0.1235
Net Cash Flow:
$45.01M
1W Performance:
+137.70%
1M Performance:
+102.41%
6M Performance:
+66.76%
1Y Performance:
+103.42%
1-Day Range:
Value
$40.41
$40.69
1-Week Range:
Value
$40.22
$40.69
52-Week Range:
Value
$16.10
$40.69

Apellis Pharmaceuticals Inc Stock (APLS) Company Profile

Name
Name
Apellis Pharmaceuticals Inc
Name
Phone
617-977-5700
Name
Address
100 FIFTH AVENUE, WALTHAM, KY
Name
Employee
733
Name
Twitter
@ApellisPharma
Name
Next Earnings Date
2024-12-05
Name
Latest SEC Filings
Name
APLS's Discussions on Twitter

Compare APLS vs VRTX, REGN, ARGX, ALNY, INSM

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
APLS icon
APLS
Apellis Pharmaceuticals Inc
40.62 5.17B 1.00B 22.39M 45.01M 0.1235
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
434.55 111.45B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
761.54 80.54B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
748.40 46.32B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
330.94 42.29B 3.71B 313.75M 465.38M 2.2571
INSM icon
INSM
Insmed Inc
163.96 35.01B 606.42M -1.28B -997.58M -6.403

Apellis Pharmaceuticals Inc Stock (APLS) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-13-26 Initiated Roth Capital Buy
Jan-28-26 Initiated Barclays Equal Weight
Jan-21-26 Upgrade BofA Securities Neutral → Buy
Nov-06-25 Initiated Wolfe Research Peer Perform
Oct-15-25 Initiated Wells Fargo Overweight
Sep-26-25 Downgrade Goldman Neutral → Sell
May-09-25 Downgrade BofA Securities Buy → Neutral
May-09-25 Downgrade Raymond James Strong Buy → Outperform
Apr-29-25 Initiated Cantor Fitzgerald Overweight
Dec-17-24 Downgrade Goldman Buy → Neutral
Nov-21-24 Initiated Morgan Stanley Equal-Weight
Oct-25-24 Initiated RBC Capital Mkts Sector Perform
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-16-24 Initiated William Blair Outperform
May-31-24 Initiated Piper Sandler Neutral
Feb-05-24 Upgrade Jefferies Hold → Buy
Dec-14-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-09-23 Initiated Goldman Buy
Nov-02-23 Initiated Mizuho Neutral
Oct-06-23 Upgrade JP Morgan Neutral → Overweight
Sep-15-23 Upgrade Wells Fargo Equal Weight → Overweight
Aug-29-23 Reiterated Citigroup Buy
Aug-03-23 Downgrade JP Morgan Overweight → Neutral
Aug-01-23 Downgrade BofA Securities Buy → Neutral
Jan-03-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-10-22 Downgrade Jefferies Buy → Hold
Jul-19-22 Initiated H.C. Wainwright Buy
Jun-17-22 Resumed Stifel Buy
Apr-14-22 Downgrade ROTH Capital Neutral → Sell
Dec-08-21 Initiated Wells Fargo Overweight
Nov-29-21 Downgrade ROTH Capital Buy → Neutral
Sep-10-21 Reiterated BMO Capital Markets Outperform
Sep-10-21 Reiterated Credit Suisse Neutral
Sep-10-21 Reiterated Needham Buy
Sep-10-21 Reiterated Oppenheimer Outperform
Sep-10-21 Downgrade Wedbush Outperform → Neutral
Aug-19-21 Initiated Jefferies Buy
Aug-19-21 Upgrade Wedbush Neutral → Outperform
May-21-21 Initiated UBS Buy
Apr-16-21 Initiated Goldman Buy
Nov-19-20 Initiated Needham Buy
Sep-01-20 Initiated Stifel Buy
Jul-20-20 Initiated ROTH Capital Buy
Jun-17-20 Initiated BTIG Research Neutral
Apr-01-20 Initiated Raymond James Strong Buy
Mar-31-20 Initiated BMO Capital Markets Outperform
Mar-11-20 Upgrade Wedbush Underperform → Neutral
Jan-07-20 Initiated SVB Leerink Mkt Perform
Dec-19-19 Initiated BofA/Merrill Buy
Nov-22-19 Initiated Wedbush Underperform
Nov-05-19 Initiated Credit Suisse Neutral
Aug-01-19 Reiterated Cantor Fitzgerald Overweight
Jul-12-19 Upgrade JP Morgan Neutral → Overweight
Mar-29-19 Initiated Robert W. Baird Outperform
Jan-23-19 Downgrade JP Morgan Overweight → Neutral
Jul-30-18 Upgrade B. Riley FBR Neutral → Buy
May-24-18 Initiated Cantor Fitzgerald Overweight
Apr-12-18 Downgrade B. Riley FBR, Inc. Buy → Neutral
Feb-08-18 Initiated B. Riley FBR, Inc. Buy
View All

Apellis Pharmaceuticals Inc Stock (APLS) Latest News

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11:00 AM

Apellis Pharmaceuticals (NASDAQ:APLS) Reaches New 12-Month HighWhat's Next? - MarketBeat

11:00 AM
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06:40 AM

Apellis Stock Soars After Biogen Deal, Momentum Score Surges—Here's What Shareholders Get - Benzinga

06:40 AM
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04:21 AM

Apellis Pharmaceuticals, Inc. (APLS) Stock Price, News, Quote & History - Yahoo! Finance Canada

04:21 AM
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Apr 04, 2026

Biogen’s Apellis Deal Reshapes Growth Outlook And Valuation Story - Yahoo Finance

Apr 04, 2026
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Apr 04, 2026

APLS PE Ratio & Valuation, Is APLS Overvalued - Intellectia AI

Apr 04, 2026
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Apr 04, 2026

Biogen Bets Big on Kidney Drugs with USD 5.6 Billion Apellis Pharmaceuticals Deal - Medical Dialogues

Apr 04, 2026
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Apr 03, 2026

Apellis Pharmaceuticals (APLS) hits 2-year high on 140% upside from Biogen merger - MSN

Apr 03, 2026
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Apr 03, 2026

Biogen (NASDAQ: BIIB) plans tender offer to acquire Apellis (APLS); materials pending - Stock Titan

Apr 03, 2026
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Apr 03, 2026

Deal Dispatch: McCormick, Unilever Merge, Sysco Acquires Jetro Restaurant Depot For $29 Billion, QVC Considers Bankruptcy - Benzinga

Apr 03, 2026
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Apr 03, 2026

Biogen to acquire Apellis in $5.6 billion deal - Ophthalmology Times

Apr 03, 2026
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Apr 03, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Downgraded by Roth Mkm to "Hold" - MarketBeat

Apr 03, 2026
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Apr 03, 2026

Comparing Apellis Pharmaceuticals With Industry Competitors In Biotechnology Industry - Sahm

Apr 03, 2026
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Apr 03, 2026

Apellis surges on $5.6B buyout deal with Biogen - MSN

Apr 03, 2026
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Apr 02, 2026

APLS Stock Soars 140% Today – Here’s Everything To Know About Apellis' Massive $5.6B Deal With Biogen - Stocktwits

Apr 02, 2026
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Apr 02, 2026

Biogen’s $5.6 Billion Apellis Buy Drives Top Trading Volume Amid Share Price Slide - Bitget

Apr 02, 2026
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Apr 02, 2026

Why Biogen Is Paying $5.6B to Buy Apellis Pharma - MedCity News

Apr 02, 2026
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Apr 02, 2026

Apellis Pharmaceuticals (APLS): Mizuho Raises Price Target Amids - gurufocus.com

Apr 02, 2026
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Apr 02, 2026

Mizuho Increases Apellis Pharmaceuticals (NASDAQ:APLS) Price Target to $41.00 - MarketBeat

Apr 02, 2026
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Apr 02, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Downgraded to "Hold" Rating by Jefferies Financial Group - MarketBeat

Apr 02, 2026
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Apr 02, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Downgraded to "Hold" Rating by William Blair - MarketBeat

Apr 02, 2026
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Apr 02, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Downgraded to Hold Rating by Cantor Fitzgerald - MarketBeat

Apr 02, 2026
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Apr 02, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Lowered to Hold Rating by Citigroup - MarketBeat

Apr 02, 2026
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Apr 02, 2026

H.C. Wainwright raises Biogen stock price target on Apellis deal - Investing.com

Apr 02, 2026
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Apr 02, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Emerges as a Prime Affordable Growth (GARP) Candidate - ChartMill

Apr 02, 2026
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Apr 02, 2026

Biogen to Acquire Apellis Pharmaceuticals in $5.6 Billion Deal - eHealth Magazine

Apr 02, 2026
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Apr 02, 2026

Roth/MKM downgrades Apellis stock rating on Biogen acquisition - Investing.com

Apr 02, 2026
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Apr 02, 2026

SHAREHOLDER ALERT: The M&A Class Action Firm Announces An Investigation of Apellis Pharmaceuticals, Inc. (NASDAQ: APLS) - Sahm

Apr 02, 2026
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Apr 01, 2026

Apellis Pharmaceuticals (APLS) Moves 135.4% Higher: Will This Strength Last? - qz.com

Apr 01, 2026
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Apr 01, 2026

Biogen Acquires Apellis for $5.6B, Shares Dip | Strategic Immunology MoveNews and Statistics - IndexBox

Apr 01, 2026
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Apr 01, 2026

APLS: Barclays Raises Price Target for Apellis Pharmaceuticals | - gurufocus.com

Apr 01, 2026
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Apr 01, 2026

APLS: JP Morgan Downgrades Apellis Pharmaceuticals, Raises Price Target | APLS Stock News - gurufocus.com

Apr 01, 2026
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Apr 01, 2026

Biogen, on the heels of a $5.6B buyout, turns its sights to early-stage assets - BioPharma Dive

Apr 01, 2026
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Apr 01, 2026

How The Apellis Pharmaceuticals (APLS) Investment Story Is Shifting With New Deals And Analyst Revisions - Yahoo Finance

Apr 01, 2026
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Apr 01, 2026

Apellis Pharmaceuticals, Inc. (APLS) Stock Forecasts - Yahoo Finance

Apr 01, 2026
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Apr 01, 2026

JPMorgan Chase & Co. Reaffirms Neutral Rating for Apellis Pharmaceuticals (NASDAQ:APLS) - MarketBeat

Apr 01, 2026
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Apr 01, 2026

Watch Biogen Buys Apellis for $5.6B to Expand Kidney Drugs - Bloomberg.com

Apr 01, 2026
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Apr 01, 2026

American Biogen bought assets of Apellis Pharmaceuticals for $5.6 billion - AKM.RU

Apr 01, 2026
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Apr 01, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Stock Price Expected to Rise, Barclays Analyst Says - MarketBeat

Apr 01, 2026
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Apr 01, 2026

Biogen to acquire Apellis Pharmaceuticals for $5.6 billion By Investing.com - Investing.com Canada

Apr 01, 2026
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Apr 01, 2026

Biogen’s $5.6bn Apellis Deal Delivers Windfall for Worldwide Healthcare Trust - TipRanks

Apr 01, 2026
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Apr 01, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Sees Large Volume IncreaseWhat's Next? - MarketBeat

Apr 01, 2026
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Apr 01, 2026

APLS Downgraded by Raymond James to Market Perform | APLS Stock News - GuruFocus

Apr 01, 2026
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Apr 01, 2026

A Look At Apellis Pharmaceuticals (APLS) Valuation After Its Sharp Recent Share Price Surge - simplywall.st

Apr 01, 2026
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Apr 01, 2026

Worldwide Healthcare Trust PLCBiogen, Inc. to acquire WWH portfolio company, Apellis Pharmaceuticals, Inc. - bolsamania.com

Apr 01, 2026
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Apr 01, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Receives "Market Perform" Rating from Raymond James Financial - MarketBeat

Apr 01, 2026
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Apr 01, 2026

Mizuho raises Apellis stock price target to $41 on Biogen deal - investing.com

Apr 01, 2026
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Apr 01, 2026

Biogen Enters $5.6 Billion Agreement to Acquire Apellis Pharmaceuticals - pharmexec.com

Apr 01, 2026
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Apr 01, 2026

APLS Downgraded by Citigroup: Target Price Lowered to $41.00 | A - GuruFocus

Apr 01, 2026
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Apr 01, 2026

This PPG Analyst Is No Longer Bullish; Here Are Top 5 Downgrades For Wednesday - Benzinga

Apr 01, 2026
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Apr 01, 2026

Biogen to Acquire Apellis for $5.6B to Strengthen Immunology Portfolio - Yahoo Finance

Apr 01, 2026
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Apr 01, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Given Neutral Rating at Citigroup - MarketBeat

Apr 01, 2026

Apellis Pharmaceuticals Inc Stock (APLS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$49.55
price down icon 1.90%
$28.34
price up icon 1.08%
$47.79
price down icon 1.05%
$91.15
price up icon 0.08%
ONC ONC
$311.43
price up icon 0.93%
$163.18
price down icon 1.52%
Cap:     |  Volume (24h):