18.94
price up icon2.99%   0.55
pre-market  Pre-market:  18.90   -0.04   -0.21%
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Apellis Pharmaceuticals Inc stock is traded at $18.94, with a volume of 1.70M. It is up +2.99% in the last 24 hours and down -12.72% over the past month. Apellis Pharmaceuticals Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system, which is an integral component of the immune system, at the level of C3, the central protein in the complement cascade. Currently it has two marketed drugs that target C3, the central protein in the complement cascade: SYFOVRE (pegcetacoplan injection) and EMPAVELI (pegcetacoplan).
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Previous Close:
$18.39
Open:
$18.84
24h Volume:
1.70M
Relative Volume:
0.63
Market Cap:
$2.42B
Revenue:
$1.00B
Net Income/Loss:
$22.39M
P/E Ratio:
153.36
EPS:
0.1235
Net Cash Flow:
$45.01M
1W Performance:
-5.63%
1M Performance:
-12.72%
6M Performance:
-23.78%
1Y Performance:
-22.28%
1-Day Range:
Value
$18.42
$19.05
1-Week Range:
Value
$18.33
$20.20
52-Week Range:
Value
$16.10
$30.48

Apellis Pharmaceuticals Inc Stock (APLS) Company Profile

Name
Name
Apellis Pharmaceuticals Inc
Name
Phone
617-977-5700
Name
Address
100 FIFTH AVENUE, WALTHAM, KY
Name
Employee
733
Name
Twitter
@ApellisPharma
Name
Next Earnings Date
2024-12-05
Name
Latest SEC Filings
Name
APLS's Discussions on Twitter

Compare APLS vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
APLS
Apellis Pharmaceuticals Inc
18.94 2.42B 1.00B 22.39M 45.01M 0.1235
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
469.34 119.23B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
745.77 78.84B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
700.45 43.35B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
313.41 41.57B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
284.05 31.51B 5.36B 287.73M 924.18M 2.5229

Apellis Pharmaceuticals Inc Stock (APLS) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-13-26 Initiated Roth Capital Buy
Jan-28-26 Initiated Barclays Equal Weight
Jan-21-26 Upgrade BofA Securities Neutral → Buy
Nov-06-25 Initiated Wolfe Research Peer Perform
Oct-15-25 Initiated Wells Fargo Overweight
Sep-26-25 Downgrade Goldman Neutral → Sell
May-09-25 Downgrade BofA Securities Buy → Neutral
May-09-25 Downgrade Raymond James Strong Buy → Outperform
Apr-29-25 Initiated Cantor Fitzgerald Overweight
Dec-17-24 Downgrade Goldman Buy → Neutral
Nov-21-24 Initiated Morgan Stanley Equal-Weight
Oct-25-24 Initiated RBC Capital Mkts Sector Perform
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-16-24 Initiated William Blair Outperform
May-31-24 Initiated Piper Sandler Neutral
Feb-05-24 Upgrade Jefferies Hold → Buy
Dec-14-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-09-23 Initiated Goldman Buy
Nov-02-23 Initiated Mizuho Neutral
Oct-06-23 Upgrade JP Morgan Neutral → Overweight
Sep-15-23 Upgrade Wells Fargo Equal Weight → Overweight
Aug-29-23 Reiterated Citigroup Buy
Aug-03-23 Downgrade JP Morgan Overweight → Neutral
Aug-01-23 Downgrade BofA Securities Buy → Neutral
Jan-03-23 Downgrade Wells Fargo Overweight → Equal Weight
Nov-10-22 Downgrade Jefferies Buy → Hold
Jul-19-22 Initiated H.C. Wainwright Buy
Jun-17-22 Resumed Stifel Buy
Apr-14-22 Downgrade ROTH Capital Neutral → Sell
Dec-08-21 Initiated Wells Fargo Overweight
Nov-29-21 Downgrade ROTH Capital Buy → Neutral
Sep-10-21 Reiterated BMO Capital Markets Outperform
Sep-10-21 Reiterated Credit Suisse Neutral
Sep-10-21 Reiterated Needham Buy
Sep-10-21 Reiterated Oppenheimer Outperform
Sep-10-21 Downgrade Wedbush Outperform → Neutral
Aug-19-21 Initiated Jefferies Buy
Aug-19-21 Upgrade Wedbush Neutral → Outperform
May-21-21 Initiated UBS Buy
Apr-16-21 Initiated Goldman Buy
Nov-19-20 Initiated Needham Buy
Sep-01-20 Initiated Stifel Buy
Jul-20-20 Initiated ROTH Capital Buy
Jun-17-20 Initiated BTIG Research Neutral
Apr-01-20 Initiated Raymond James Strong Buy
Mar-31-20 Initiated BMO Capital Markets Outperform
Mar-11-20 Upgrade Wedbush Underperform → Neutral
Jan-07-20 Initiated SVB Leerink Mkt Perform
Dec-19-19 Initiated BofA/Merrill Buy
Nov-22-19 Initiated Wedbush Underperform
Nov-05-19 Initiated Credit Suisse Neutral
Aug-01-19 Reiterated Cantor Fitzgerald Overweight
Jul-12-19 Upgrade JP Morgan Neutral → Overweight
Mar-29-19 Initiated Robert W. Baird Outperform
Jan-23-19 Downgrade JP Morgan Overweight → Neutral
Jul-30-18 Upgrade B. Riley FBR Neutral → Buy
May-24-18 Initiated Cantor Fitzgerald Overweight
Apr-12-18 Downgrade B. Riley FBR, Inc. Buy → Neutral
Feb-08-18 Initiated B. Riley FBR, Inc. Buy
View All

Apellis Pharmaceuticals Inc Stock (APLS) Latest News

pulisher
03:01 AM

Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) Receives Average Rating of "Moderate Buy" from Brokerages - MarketBeat

03:01 AM
pulisher
Mar 15, 2026

Assessing Apellis Pharmaceuticals (APLS) Valuation After Weaker Returns And EMPAVELI Label Expansion - Yahoo Finance UK

Mar 15, 2026
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Mar 14, 2026

Integral Health Asset Management LLC Purchases Shares of 250,000 Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Mar 14, 2026
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Mar 14, 2026

Apellis Pharmaceuticals (APLS) Receives Buy Rating Amid Growth P - GuruFocus

Mar 14, 2026
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Mar 13, 2026

Apellis (NASDAQ: APLS) CEO gifts 129,738 shares via family trusts - Stock Titan

Mar 13, 2026
pulisher
Mar 13, 2026

APLS: Roth Capital Initiates Coverage with 'Buy' Rating at $31.00 | APLS Stock News - GuruFocus

Mar 13, 2026
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Mar 13, 2026

Apellis stock wins new Buy at Roth on Syfovre (APLS:NASDAQ) - Seeking Alpha

Mar 13, 2026
pulisher
Mar 13, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Coverage Initiated at Roth Mkm - MarketBeat

Mar 13, 2026
pulisher
Mar 13, 2026

Roth Capital initiates coverage of Apellis Pharmaceuticals (APLS) with buy recommendation - MSN

Mar 13, 2026
pulisher
Mar 10, 2026

Here is Why JPMorgan is Overweight on Apellis Pharma (APLS) - Finviz

Mar 10, 2026
pulisher
Mar 08, 2026

How Apellis Adding Ex-Pfizer R&D Chief Mikael Dolsten to Its Board Will Impact Apellis (APLS) Investors - simplywall.st

Mar 08, 2026
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Mar 08, 2026

Rhenman & Partners Asset Management AB Has $5.26 Million Stock Position in Apellis Pharmaceuticals, Inc. $APLS - MarketBeat

Mar 08, 2026
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Mar 07, 2026

Apellis Pharmaceuticals Balances Growth With Revenue Headwinds - The Globe and Mail

Mar 07, 2026
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Mar 07, 2026

Apellis Sells Aspaveli Ex-US Royalties to Sobi for Up to $300M - MSN

Mar 07, 2026
pulisher
Mar 06, 2026

Apellis Adds Ex Pfizer R&D Chief To Board As Growth Plans Evolve - Sahm

Mar 06, 2026
pulisher
Mar 06, 2026

(APLS) Price Dynamics and Execution-Aware Positioning - Stock Traders Daily

Mar 06, 2026
pulisher
Mar 05, 2026

JP Morgan Raises Price Target for APLS, Maintains Overweight Rat - GuruFocus

Mar 05, 2026
pulisher
Mar 05, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Price Target Raised to $37.00 at JPMorgan Chase & Co. - MarketBeat

Mar 05, 2026
pulisher
Mar 05, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Price Target Raised to $20.00 at Mizuho - MarketBeat

Mar 05, 2026
pulisher
Mar 05, 2026

APLS: Mizuho Maintains Rating, Raises Price Target | APLS Stock News - GuruFocus

Mar 05, 2026
pulisher
Mar 05, 2026

Assessing Apellis Pharmaceuticals: Insights From 11 Financial Analysts - Benzinga

Mar 05, 2026
pulisher
Mar 05, 2026

APLS Earning Date, Earning Analysis and Earning Prediction - Intellectia AI

Mar 05, 2026
pulisher
Mar 04, 2026

Update Recap: Will Apellis Pharmaceuticals Inc benefit from geopolitical trendsMarket Performance Summary & Daily Technical Forecast Reports - baoquankhu1.vn

Mar 04, 2026
pulisher
Mar 03, 2026

Apellis Pharmaceuticals (APLS) director receives new stock options and RSUs - Stock Titan

Mar 03, 2026
pulisher
Mar 03, 2026

Apellis (APLS) director Mikael Dolsten submits initial Form 3 insider filing - Stock Titan

Mar 03, 2026
pulisher
Mar 03, 2026

Apellis Pharmaceuticals (APLS) Stock Analysis: Exploring a 62.73% Upside Potential in Biotech - DirectorsTalk Interviews

Mar 03, 2026
pulisher
Mar 03, 2026

Apellis Pharmaceuticals Details SYFOVRE, EMPAVELI Growth Plans and FcRn Gene-Editing Push at TD Cowen Conf. - MarketBeat

Mar 03, 2026
pulisher
Mar 02, 2026

Apellis adds former Pfizer research chief to board - Investing.com

Mar 02, 2026
pulisher
Mar 02, 2026

Apellis Pharmaceuticals appoints Mikael Dolsten to board of directors - Investing.com Australia

Mar 02, 2026
pulisher
Mar 02, 2026

Apellis Pharmaceuticals2026 Funding Rounds & List of Investors - Tracxn

Mar 02, 2026
pulisher
Mar 02, 2026

Apellis Pharmaceuticals, Inc. $APLS Shares Sold by Vanguard Group Inc. - MarketBeat

Mar 02, 2026
pulisher
Mar 02, 2026

Apellis Pharmaceuticals Adds Mikael Dolsten to Board - TipRanks

Mar 02, 2026
pulisher
Mar 02, 2026

Apellis Pharmaceuticals appoints Mikael Dolsten to board of directors By Investing.com - Investing.com India

Mar 02, 2026
pulisher
Mar 02, 2026

Apellis adds former Pfizer research chief to board By Investing.com - Investing.com Canada

Mar 02, 2026
pulisher
Mar 02, 2026

Apellis Announces Mikael Dolsten, M.D., Ph.D., to Join Board of Directors - Bitget

Mar 02, 2026
pulisher
Mar 02, 2026

Mikael Dolsten joins Apellis Board as Class I director - TradingView

Mar 02, 2026
pulisher
Mar 02, 2026

Mikael Dolsten joins Apellis (NASDAQ: APLS) board with equity grants - Stock Titan

Mar 02, 2026
pulisher
Mar 02, 2026

Pfizer veteran who led R&D for 16 years joins Apellis board - Stock Titan

Mar 02, 2026
pulisher
Feb 28, 2026

A Look At Apellis Pharmaceuticals (APLS) Valuation After 2025 Results And Softer Syfovre Growth Outlook - simplywall.st

Feb 28, 2026
pulisher
Feb 28, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Lowered to Sell Rating by Wall Street Zen - MarketBeat

Feb 28, 2026
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Feb 27, 2026

HC Wainwright Issues Optimistic Outlook for APLS Earnings - MarketBeat

Feb 27, 2026
pulisher
Feb 26, 2026

Assessing Apellis Pharmaceuticals (APLS) Valuation After Prolonged Share Price Weakness - Yahoo Finance

Feb 26, 2026
pulisher
Feb 26, 2026

Apellis (APLS) Q4 2025 Earnings Call Transcript - AOL.com

Feb 26, 2026
pulisher
Feb 26, 2026

Analysts Issue Forecasts for APLS FY2030 Earnings - MarketBeat

Feb 26, 2026
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Feb 26, 2026

Apellis price target lowered to $18 from $20 at Wedbush - Yahoo Finance

Feb 26, 2026
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Feb 26, 2026

Apellis Pharmaceuticals Experiences Revision in Stock Evaluation Amidst Market Challenges - Markets Mojo

Feb 26, 2026
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Feb 26, 2026

RBC Capital Reaffirms Their Hold Rating on Apellis Pharmaceuticals (APLS) - The Globe and Mail

Feb 26, 2026
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Feb 25, 2026

Apogee Therapeutics Stock Up 100% as Fund Lifts Stake to $28 Million - AOL.com

Feb 25, 2026
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Feb 25, 2026

S&E In Brief: Commercial Updates From The SMID Cap Universe - Citeline News & Insights

Feb 25, 2026
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Feb 25, 2026

RBC Capital Adjusts Price Target for Apellis Pharmaceuticals (AP - GuruFocus

Feb 25, 2026
pulisher
Feb 25, 2026

Apellis Pharmaceuticals (NASDAQ:APLS) Price Target Cut to $44.00 by Analysts at Citigroup - MarketBeat

Feb 25, 2026

Apellis Pharmaceuticals Inc Stock (APLS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$45.65
price down icon 0.48%
$28.06
price down icon 1.72%
$52.56
price down icon 1.55%
$91.19
price up icon 1.21%
$139.50
price down icon 0.01%
biotechnology ONC
$284.05
price down icon 0.44%
Cap:     |  Volume (24h):