309.66
price down icon3.27%   -10.47
after-market After Hours: 310.05 0.39 +0.13%
loading
Alnylam Pharmaceuticals Inc stock is traded at $309.66, with a volume of 1.50M. It is down -3.27% in the last 24 hours and down -3.36% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
See More
Previous Close:
$320.13
Open:
$326.09
24h Volume:
1.50M
Relative Volume:
1.15
Market Cap:
$41.32B
Revenue:
$3.71B
Net Income/Loss:
$313.75M
P/E Ratio:
137.19
EPS:
2.2571
Net Cash Flow:
$465.38M
1W Performance:
-3.87%
1M Performance:
-3.36%
6M Performance:
-35.71%
1Y Performance:
+32.02%
1-Day Range:
Value
$306.00
$326.53
1-Week Range:
Value
$306.00
$343.36
52-Week Range:
Value
$228.28
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,500
Name
Twitter
@alnylam
Name
Next Earnings Date
2026-04-30
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY vs VRTX, REGN, ARGX, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
309.66 41.32B 3.71B 313.75M 465.38M 2.2571
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
441.20 112.22B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
750.57 79.35B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
849.04 52.80B 4.16B 1.29B 734.26M 19.58
ONC icon
ONC
Beone Medicines Ltd Adr
323.87 35.95B 5.36B 287.73M 924.18M 2.5229

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-16-26 Downgrade Jefferies Buy → Hold
Jan-28-26 Resumed Barclays Overweight
Jan-07-26 Resumed Oppenheimer Outperform
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
View All

Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
12:07 PM

Alnylam Pharmaceuticals (ALNY) presents Vutrisiran ATTR-CM data at ACC.26 - MSN

12:07 PM
pulisher
07:43 AM

JP Morgan Maintains Alnylam Pharmaceuticals (ALNY) Overweight Recommendation - MSN

07:43 AM
pulisher
05:03 AM

GF Fund Management CO. LTD. Boosts Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

05:03 AM
pulisher
Apr 17, 2026

A Look At Alnylam Pharmaceuticals (ALNY) Valuation After Recent Choppy Trading And Rich P/E Multiple - Yahoo Finance

Apr 17, 2026
pulisher
Apr 17, 2026

RNAi Technology Market to Reach USD 9.58 Billion by 2033 at 15.26% - openPR.com

Apr 17, 2026
pulisher
Apr 17, 2026

Alnylam to Webcast Conference Call Discussing First Quarter 2026 Financial Results - BioSpace

Apr 17, 2026
pulisher
Apr 16, 2026

Alnylam (ALNY) slides 4% as valuation concerns linger after recent analyst reset - Quiver Quantitative

Apr 16, 2026
pulisher
Apr 16, 2026

KBC Group NV Has $138.46 Million Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Apr 16, 2026
pulisher
Apr 16, 2026

Wells Fargo raises Alnylam (ALNY) revenue estimates for Amvuttra despite projected margin compression - MSN

Apr 16, 2026
pulisher
Apr 15, 2026

Alnylam Pharmaceuticals (ALNY) Earnings Expected to Grow: Should You Buy? - Eastern Progress

Apr 15, 2026
pulisher
Apr 15, 2026

Is the Options Market Predicting a Spike in Alnylam Pharmaceuticals Stock? - Eastern Progress

Apr 15, 2026
pulisher
Apr 15, 2026

Alnylam Pharmaceuticals (ALNY) Surpasses Q4 Earnings Estimates - Eastern Progress

Apr 15, 2026
pulisher
Apr 14, 2026

Did New Vutrisiran Data and FCF Breakeven Just Shift Alnylam Pharmaceuticals' (ALNY) Investment Narrative? - simplywall.st

Apr 14, 2026
pulisher
Apr 14, 2026

Sumitomo Mitsui Trust Group Inc. Has $130.34 Million Stock Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Apr 14, 2026
pulisher
Apr 13, 2026

Truist Financial Lowers Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target to $505.00 - MarketBeat

Apr 13, 2026
pulisher
Apr 13, 2026

Whats the beta of Alnylam Pharmaceuticals Inc stockWeekly Gains Report & Short-Term Swing Trade Alerts - baoquankhu1.vn

Apr 13, 2026
pulisher
Apr 13, 2026

Massachusetts Financial Services Co. MA Boosts Stock Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Apr 13, 2026
pulisher
Apr 13, 2026

Oligonucleotides Market Research and Competitive Landscape Report 2026 Featuring Novartis, Astellas, Alnylam Pharmaceuticals, Ionis Pharmaceuticals - Yahoo Finance

Apr 13, 2026
pulisher
Apr 13, 2026

Alnylam Pharmaceuticals, Inc. $ALNY Stock Holdings Trimmed by Baillie Gifford & Co. - MarketBeat

Apr 13, 2026
pulisher
Apr 12, 2026

Alnylam to Webcast Presentation at 2013 UBS Global Healthcare Conference - Yahoo

Apr 12, 2026
pulisher
Apr 12, 2026

Is Alnylam Pharmaceuticals (ALNY) The Best Growth Stock? - Insider Monkey

Apr 12, 2026
pulisher
Apr 12, 2026

A Look At Alnylam Pharmaceuticals’ (ALNY) Valuation After Recent Mixed Share Price Performance - simplywall.st

Apr 12, 2026
pulisher
Apr 11, 2026

10 Best Growth Stocks to Buy With Highest Upside Potential - Insider Monkey

Apr 11, 2026
pulisher
Apr 10, 2026

Alnylam Achieves Leading Trading Position Despite Declining Volume as Revenue Surges - Bitget

Apr 10, 2026
pulisher
Apr 10, 2026

ALNY (Alnylam Pharmaceuticals) Earnings Yield (Joel Greenblatt) % : 1.13% (As of Dec. 2025) - GuruFocus

Apr 10, 2026
pulisher
Apr 10, 2026

Is the options market predicting a spike in Alnylam Pharmaceuticals stock? - MSN

Apr 10, 2026
pulisher
Apr 10, 2026

ALNY Stock Price, Quote & Chart | ALNYLAM PHARMACEUTICALS INC (NASDAQ:ALNY) - ChartMill

Apr 10, 2026
pulisher
Apr 09, 2026

Alnylam Pharmaceuticals (ALNY) Achieved Free Cash Flow Breakeven in 2025 - Yahoo Finance

Apr 09, 2026
pulisher
Apr 08, 2026

RBC Capital Maintains Alnylam Pharmaceuticals(ALNY.US) With Buy Rating, Maintains Target Price $450 - Moomoo

Apr 08, 2026
pulisher
Apr 08, 2026

Alnylam Cardiovascular Data Highlights Potential Upside In ATTR-CM And Hypertension - Yahoo Finance

Apr 08, 2026
pulisher
Apr 08, 2026

Antisense Oligonucleotides Market 2026-2033 | US$ 5,286.96 - openPR.com

Apr 08, 2026
pulisher
Apr 08, 2026

Trading Systems Reacting to (ALNY) Volatility - Stock Traders Daily

Apr 08, 2026
pulisher
Apr 08, 2026

Mach Natural Resources, Mesoblast And Other Big Stocks Moving Lower In Tuesday's Pre-Market Session - Sahm

Apr 08, 2026
pulisher
Apr 07, 2026

Alnylam (ALNY) CHRO McLaughlin sells shares worth $1.27 million By Investing.com - Investing.com India

Apr 07, 2026
pulisher
Apr 07, 2026

Alnylam (ALNY) CHRO McLaughlin sells shares worth $1.27 million - Investing.com

Apr 07, 2026
pulisher
Apr 07, 2026

Alnylam (NASDAQ: ALNY) HR chief auto-sells shares to cover RSU taxes - Stock Titan

Apr 07, 2026
pulisher
Apr 07, 2026

Alnylam (NASDAQ: ALNY) HR chief details stock and option holdings - Stock Titan

Apr 07, 2026
pulisher
Apr 07, 2026

Is the options market signaling a potential surge in Alnylam Pharmaceuticals shares? - Bitget

Apr 07, 2026
pulisher
Apr 07, 2026

Book value per share of Alnylam Pharmaceuticals, Inc – LSE:0HD2 - TradingView

Apr 07, 2026
pulisher
Apr 07, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) Shares Gap DownHere's What Happened - MarketBeat

Apr 07, 2026
pulisher
Apr 06, 2026

How New Vutrisiran Outcomes and Zilebesiran Safety Data Will Impact Alnylam Pharmaceuticals (ALNY) Investors - simplywall.st

Apr 06, 2026
pulisher
Apr 06, 2026

Alnylam (NASDAQ: ALNY) sets 2026 virtual meeting, board elections and pay vote - Stock Titan

Apr 06, 2026
pulisher
Apr 06, 2026

[144] ALNYLAM PHARMACEUTICALS, INC. SEC Filing - Stock Titan

Apr 06, 2026
pulisher
Apr 06, 2026

Alnylam Pharmaceuticals, Inc. (ALNY) Options Chain - Yahoo! Finance Canada

Apr 06, 2026
pulisher
Apr 06, 2026

Alnylam Pharmaceuticals, Inc. (ALNY) stock price, news, quote and history - Yahoo Finance UK

Apr 06, 2026
pulisher
Apr 06, 2026

Porphyria Treatment Market to Reach US$ 358.64 Million by 2032 - openPR.com

Apr 06, 2026
pulisher
Apr 06, 2026

[ARS] ALNYLAM PHARMACEUTICALS, INC. SEC Filing - Stock Titan

Apr 06, 2026
pulisher
Apr 05, 2026

Alnylam announces proposed offering of $500M convertible senior notes - MSN

Apr 05, 2026

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading
ONC ONC
$323.87
price up icon 0.99%
$144.48
price up icon 1.18%
$849.04
price up icon 2.50%
$148.63
price down icon 0.43%
$102.92
price up icon 0.78%
Cap:     |  Volume (24h):