301.98
price down icon1.01%   -3.08
after-market After Hours: 306.59 4.61 +1.53%
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Alnylam Pharmaceuticals Inc stock is traded at $301.98, with a volume of 2.28M. It is down -1.01% in the last 24 hours and up +0.26% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
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Previous Close:
$305.06
Open:
$302.43
24h Volume:
2.28M
Relative Volume:
2.08
Market Cap:
$40.32B
Revenue:
$4.29B
Net Income/Loss:
$577.22M
P/E Ratio:
71.75
EPS:
4.2086
Net Cash Flow:
$641.34M
1W Performance:
+1.52%
1M Performance:
+0.26%
6M Performance:
-33.08%
1Y Performance:
+3.10%
1-Day Range:
Value
$297.62
$305.68
1-Week Range:
Value
$291.84
$305.98
52-Week Range:
Value
$284.28
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,500
Name
Twitter
@alnylam
Name
Next Earnings Date
2026-04-30
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY vs VRTX, REGN, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
301.98 40.73B 4.29B 577.22M 641.34M 4.2086
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
447.54 113.70B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
614.78 65.16B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
835.99 52.14B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
157.48 32.87B 742.00K -1.37B -1.07B -7.0731

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-16-26 Downgrade Jefferies Buy → Hold
Jan-28-26 Resumed Barclays Overweight
Jan-07-26 Resumed Oppenheimer Outperform
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
View All

Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
May 28, 2026

How Investors May Respond To Alnylam Pharmaceuticals (ALNY) Adding Scientific Depth Amid RNAi Pipeline Scrutiny - simplywall.st

May 28, 2026
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May 28, 2026

ALNY Stock Price, Quote & Chart | ALNYLAM PHARMACEUTICALS INC (NASDAQ:ALNY) - ChartMill

May 28, 2026
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May 28, 2026

Alnylam Pharmaceuticals, Inc. 8-K SEC Filing Summary – Corporate Details and Exchange Listing (May 20, 2026) - Minichart

May 28, 2026
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May 27, 2026

Alnylam (NASDAQ: ALNY) expands board and details 2026 shareholder meeting votes - Stock Titan

May 27, 2026
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May 27, 2026

RBC Capital Maintains Alnylam Pharmaceuticals(ALNY.US) With Buy Rating, Maintains Target Price $445 - Moomoo

May 27, 2026
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May 27, 2026

Ionis, Alnylam, BioMarin up as Citi starts at buy on catalyst and growth outlook - MSN

May 27, 2026
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May 26, 2026

ALNY Technical Analysis | Trend, Signals & Chart Patterns | ALNYLAM PHARMACEUTICALS INC (NASDAQ:ALNY) - ChartMill

May 26, 2026
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May 25, 2026

Citi Initiates Alnylam (ALNY) With Buy Rating - Insider Monkey

May 25, 2026
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May 25, 2026

Alnylam Pharmaceuticals Q3 2025 Earnings Preview - MSN

May 25, 2026
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May 25, 2026

Alnylam Pharmaceuticals, Inc. (ALNY) Stock Analysis: A 49.88% Potential Upside for Biotech Investors - DirectorsTalk Interviews

May 25, 2026
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May 23, 2026

Assessing Alnylam Pharmaceuticals (ALNY) Valuation After Mixed Share Performance And Strong AMVUTTRA Uptake - simplywall.st

May 23, 2026
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May 22, 2026

Director at Alnylam (NASDAQ: ALNY) granted RSUs and stock options - Stock Titan

May 22, 2026
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May 22, 2026

Alnylam (NASDAQ: ALNY) awards RSUs and options to board director - Stock Titan

May 22, 2026
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May 22, 2026

Director at Alnylam (NASDAQ: ALNY) receives RSUs and options - Stock Titan

May 22, 2026
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May 22, 2026

Alnylam (ALNY) director gets new RSUs, options and reports trust holdings - Stock Titan

May 22, 2026
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May 22, 2026

Director Peter Kellogg granted RSUs and stock options at Alnylam (NASDAQ: ALNY) - Stock Titan

May 22, 2026
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May 22, 2026

ALNY (ALNY) director granted 671 RSUs and 1,441 options at $298.48 - Stock Titan

May 22, 2026
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May 22, 2026

Alnylam (ALNY) director Olivier Brandicourt receives new RSU and option grants - Stock Titan

May 22, 2026
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May 22, 2026

ALNY (ALNY) director Dennis Ausiello granted RSUs and stock options awards - Stock Titan

May 22, 2026
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May 22, 2026

Alnylam (ALNY) director granted RSUs and stock options in new equity awards - Stock Titan

May 22, 2026
pulisher
May 22, 2026

Discipline and Rules-Based Execution in ALNY Response - Stock Traders Daily

May 22, 2026
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May 22, 2026

Alnylam Pharmaceuticals (ALNY) 10K Form and Latest SEC Filings 2026 - MarketBeat

May 22, 2026
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May 20, 2026

Alnylam Pharmaceuticals’ SWOT analysis: stock faces margin pressure By Investing.com - Investing.com South Africa

May 20, 2026
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May 20, 2026

Alnylam Pharmaceuticals’ SWOT analysis: stock faces margin pressure - Investing.com

May 20, 2026
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May 20, 2026

Alnylam Q1 Earnings Beat Estimates, Amvuttra Sales Drive Y/Y Growth - Eastern Progress

May 20, 2026
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May 20, 2026

Alnylam Pharmaceuticals Inc Annual Shareholders Meeting Transcript - GuruFocus

May 20, 2026
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May 20, 2026

ALNY Technical Analysis & Stock Price Forecast - Intellectia AI

May 20, 2026
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May 19, 2026

ALNY Initiated Coverage by Citigroup -- Price Target Set at $380 - GuruFocus

May 19, 2026
pulisher
May 19, 2026

Citi Initiates Coverage on Biotech Stocks: Ionis (IONS), Alnylam (ALNY), BioMarin (BMRN) - GuruFocus

May 19, 2026
pulisher
May 19, 2026

Ionis, Alnylam, BioMarin are new Buys at Citi (ALNY:NASDAQ) - Seeking Alpha

May 19, 2026
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May 19, 2026

Alnylam Issues 2025 Corporate Responsibility Report - BioSpace

May 19, 2026
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May 19, 2026

Alnylam commits $2M to frontline care navigators in Boston - Stock Titan

May 19, 2026
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May 19, 2026

How HELIOS-B Phase 3 Vutrisiran Data and Real-World Evidence Expansion Will Impact Alnylam (ALNY) Investors - simplywall.st

May 19, 2026
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May 19, 2026

Immunic appoints Biogen, Cubist veteran Mike Bonney as board chair ahead of key MS trial readout - Proactive financial news

May 19, 2026
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May 18, 2026

Daily Brief Health Care: Dermavon Holdings, Alebund Pharmaceuticals Jiangsu, Alnylam Pharmaceuticals, Artrya , Bavarian Nordic A/S, Cardinal Health, Dexcom Inc, American Shared Hospital Servi, Eli Lilly & Co, Abeona Therapeutics and more - Smartkarma

May 18, 2026
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May 18, 2026

Protein Synthesis Research Market to Reach $42.8 Billion by 2031, Driven by Surging CGT Investment - GlobeNewswire Inc.

May 18, 2026
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May 18, 2026

How Investors Are Reacting To Alnylam Pharmaceuticals (ALNY) New HELIOS-B Vutrisiran Data And Real-World Study - Yahoo Finance

May 18, 2026
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May 18, 2026

Alnylam Pharmaceuticals, Inc. $ALNY Shares Bought by iA Global Asset Management Inc. - MarketBeat

May 18, 2026
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May 18, 2026

Alnylam’s Vutrisiran Data And Real-World Study Contrast With Depressed Valuation - Yahoo Finance

May 18, 2026
pulisher
May 18, 2026

Alnylam Pharmaceuticals, Inc. $ALNY Position Reduced by DNB Asset Management AS - MarketBeat

May 18, 2026
pulisher
May 18, 2026

Is the options market predicting a spike in Alnylam Pharmaceuticals stock? - MSN

May 18, 2026
pulisher
May 16, 2026

ALNY Financials: Revenue Breakdown, Margins & Competitor Comparison - Intellectia AI

May 16, 2026
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May 16, 2026

Alnylam Pharmaceuticals, Inc. $ALNY Shares Bought by ANTIPODES PARTNERS Ltd - MarketBeat

May 16, 2026
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May 15, 2026

Alnylam Pharmaceuticals Adjusts Valuation Grade Amid Strong Financial Performance Indicators - Markets Mojo

May 15, 2026
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May 15, 2026

A Look At Alnylam Pharmaceuticals (ALNY) Valuation As HELIOS B Data And TTR Guidance Reassure Investors - simplywall.st

May 15, 2026
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May 14, 2026

Alnylam teams up with Viz.ai and American Heart Association to advance ATTR-CM care - MSN

May 14, 2026
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May 14, 2026

Alnylam reiterates 2026 TTR sales guidance of $4.4B-$4.7B while expanding TRITON-CM enrollment to about 1,750 - MSN

May 14, 2026
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May 14, 2026

Alnylam (NASDAQ: ALNY) director exercises 11,250 stock options at $70.20 - Stock Titan

May 14, 2026
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May 14, 2026

Is Alnylam (ALNY) One of the Best Aggressive Growth Stocks to Buy? - Insider Monkey

May 14, 2026
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May 14, 2026

Capital World Investors holds 10.9M Alnylam shares (NASDAQ: ALNY) - Stock Titan

May 14, 2026
pulisher
May 14, 2026

Capital Research holds 9.47M shares of Alnylam (NASDAQ: ALNY) in 13G/A - Stock Titan

May 14, 2026

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$157.48
price up icon 1.84%
ONC ONC
$287.92
price down icon 0.92%
$835.99
price down icon 0.30%
$55.76
price up icon 2.35%
$95.95
price up icon 2.69%
Cap:     |  Volume (24h):