392.10
price up icon0.24%   0.93
after-market After Hours: 392.10
loading
Alnylam Pharmaceuticals Inc stock is traded at $392.10, with a volume of 1.04M. It is up +0.24% in the last 24 hours and down -14.86% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
See More
Previous Close:
$391.17
Open:
$394.18
24h Volume:
1.04M
Relative Volume:
0.94
Market Cap:
$51.80B
Revenue:
$3.21B
Net Income/Loss:
$43.57M
P/E Ratio:
1,630.35
EPS:
0.2405
Net Cash Flow:
$221.36M
1W Performance:
-3.06%
1M Performance:
-14.86%
6M Performance:
+27.01%
1Y Performance:
+59.02%
1-Day Range:
Value
$389.00
$400.24
1-Week Range:
Value
$387.03
$414.22
52-Week Range:
Value
$205.87
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,230
Name
Twitter
@alnylam
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
392.10 51.68B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
449.52 115.43B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
749.79 78.44B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
862.05 52.42B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
198.46 42.80B 447.02M -1.18B -906.14M -6.1812

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
View All

Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
Dec 17, 2025

Alnylam launching $250 million biomanufacturing expansion in Norton - The Boston Globe

Dec 17, 2025
pulisher
Dec 17, 2025

Alnylam's $250M Norton facility upgrade aims to slash need for 20 plants down to 2 - The Business Journals

Dec 17, 2025
pulisher
Dec 17, 2025

Alnylam to Invest $250M in U.S. Manufacturing Expansion for RNAi Therapeutics - citybiz

Dec 17, 2025
pulisher
Dec 17, 2025

Alnylam (ALNY) Advances Norton Facility with $250M Investment - GuruFocus

Dec 17, 2025
pulisher
Dec 17, 2025

Alnylam to invest $250 million in expanding RNA drug manufacturing By Investing.com - Investing.com South Africa

Dec 17, 2025
pulisher
Dec 17, 2025

Alnylam Pharmaceuticals to Invest $250 Million on Enzymatic Ligation Manufacturing Platform - marketscreener.com

Dec 17, 2025
pulisher
Dec 17, 2025

Alnylam to invest $250 million to add enzymatic ligation platform - marketscreener.com

Dec 17, 2025
pulisher
Dec 17, 2025

Alnylam to Invest $250 Million to Add Enzymatic Ligation Platform to U.S. Manufacturing Facility to Meet Growing Global Demand for RNAi Therapeutics - Business Wire

Dec 17, 2025
pulisher
Dec 17, 2025

Sanders Morris Harris LLC Makes New Investment in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Dec 17, 2025
pulisher
Dec 16, 2025

Lululemon, Biogen to exit Nasdaq 100 with Alnylam, Seagate among additions - MSN

Dec 16, 2025
pulisher
Dec 16, 2025

Alnylam announces Health Canada approval of Amvuttra® - marketscreener.com

Dec 16, 2025
pulisher
Dec 16, 2025

Alnylam Pharmaceuticals (ALNY) Stock Price, Quote, News & History - Benzinga

Dec 16, 2025
pulisher
Dec 16, 2025

Alnylam Announces Health Canada Approval of AMVUTTRA® (vutrisiran), the First and Only RNAi Therapeutic for the Treatment of Cardiomyopathy in Adult Patients with ATTR Amyloidosis - Yahoo Finance

Dec 16, 2025
pulisher
Dec 16, 2025

Gene Therapy Market to Reach US$ 35.91 Billion by 2033 at 23.1% - openPR.com

Dec 16, 2025
pulisher
Dec 16, 2025

Is Alnylam Entering A Corrective Phase After A Strong Run? - Sahm

Dec 16, 2025
pulisher
Dec 16, 2025

Assessing Alnylam Pharmaceuticals’ (ALNY) Valuation After Its Inclusion in the Nasdaq 100 Index - Yahoo Finance

Dec 16, 2025
pulisher
Dec 16, 2025

Is Alnylam (ALNY) Using Nasdaq 100 Inclusion To Quietly Redefine Its Capital Allocation Playbook? - simplywall.st

Dec 16, 2025
pulisher
Dec 15, 2025

Alnylam Pharmaceuticals (ALNY) Rating Maintained, Price Target L - GuruFocus

Dec 15, 2025
pulisher
Dec 15, 2025

Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target Cut to $351.00 by Analysts at Leerink Partners - MarketBeat

Dec 15, 2025
pulisher
Dec 15, 2025

Alnylam, Seagate among six stocks added to Nasdaq-100 in annual rebalance - MSN

Dec 15, 2025
pulisher
Dec 15, 2025

Peptidream reveals milestone in Alnylam collaboration - BioWorld MedTech

Dec 15, 2025
pulisher
Dec 15, 2025

Liontrust Investment Partners LLP Cuts Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Dec 15, 2025
pulisher
Dec 14, 2025

Alnylam Pharmaceuticals (ALNY) Reports Q1 Loss, Tops Revenue Estimates - sharewise.com

Dec 14, 2025
pulisher
Dec 14, 2025

NASDAQ adding Alnylam, Ferrovial, Insmed, Monolithic Power at open on 12/22 - MSN

Dec 14, 2025
pulisher
Dec 14, 2025

Holocene Advisors LP Invests $194.62 Million in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Dec 14, 2025
pulisher
Dec 14, 2025

China Universal Asset Management Co. Ltd. Trims Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Dec 14, 2025
pulisher
Dec 14, 2025

A look at Alnylam Pharmaceuticals (ALNY) valuation after Nasdaq 100 inclusion and convertible notes repurchase - simplywall.st

Dec 14, 2025
pulisher
Dec 13, 2025

Alnylam Pharmaceuticals: Challenges In The TTR Space And Few Late-Stage Catalysts Are A Concern - Seeking Alpha

Dec 13, 2025
pulisher
Dec 13, 2025

Seagate, Alnylam among six companies set to join Nasdaq 100 - MSN

Dec 13, 2025
pulisher
Dec 13, 2025

Alnylam (ALNY) and Seagate (STX) Join Nasdaq 100 Index - GuruFocus

Dec 13, 2025
pulisher
Dec 13, 2025

Gilder Gagnon Howe & Co. LLC Sells 8,487 Shares of Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Dec 13, 2025
pulisher
Dec 13, 2025

Eventide Asset Management LLC Sells 40,548 Shares of Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Dec 13, 2025
pulisher
Dec 13, 2025

Alnylam Pharmaceuticals, Inc. $ALNY Shares Sold by Bellevue Group AG - MarketBeat

Dec 13, 2025
pulisher
Dec 12, 2025

Implied Volatility Surging for Alnylam Pharmaceuticals Stock Options - sharewise.com

Dec 12, 2025
pulisher
Dec 12, 2025

Seagate, Alnylam Are Among Six Companies Set to Join Nasdaq 100 - Bloomberg.com

Dec 12, 2025
pulisher
Dec 12, 2025

Annual Changes to the Nasdaq-100 Index® - GlobeNewswire Inc.

Dec 12, 2025
pulisher
Dec 12, 2025

How Good Is Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY), When It Comes To ROE? - Yahoo Finance

Dec 12, 2025
pulisher
Dec 12, 2025

Is It Too Late to Consider Alnylam Pharmaceuticals After Its Huge 2025 Share Price Surge? - simplywall.st

Dec 12, 2025
pulisher
Dec 12, 2025

Alnylam Announces Partial Repurchase of 1.00% Convertible Senior Notes Due 2027 - BioSpace

Dec 12, 2025
pulisher
Dec 12, 2025

Is Alnylam Pharmaceuticals Stock Built to Withstand More Downside? - Trefis

Dec 12, 2025
pulisher
Dec 11, 2025

$73 Billion Non-Opioid Therapeutics Industry Assessment, - GlobeNewswire

Dec 11, 2025
pulisher
Dec 11, 2025

$73 Billion Non-Opioid Therapeutics Industry Assessment, 2032 Featuring AbbVie, GlaxoSmithKline, Acorda Therapeutics, Allay Therapeutics, Alnylam Pharmaceuticals and Other Key Players - Yahoo Finance

Dec 11, 2025
pulisher
Dec 11, 2025

Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target Raised to $508.00 - MarketBeat

Dec 11, 2025
pulisher
Dec 11, 2025

WINTON GROUP Ltd Makes New Investment in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Dec 11, 2025
pulisher
Dec 11, 2025

Alnylam (ALNY) Announces $34.4M Convertible Notes Repurchase - GuruFocus

Dec 11, 2025
pulisher
Dec 11, 2025

Alnylam Pharmaceuticals stock price target raised by Stifel to $508 - Investing.com

Dec 11, 2025
pulisher
Dec 11, 2025

ALNY: Stifel Raises Price Target to $508, Maintains Buy Rating | ALNY Stock News - GuruFocus

Dec 11, 2025
pulisher
Dec 11, 2025

Alnylam to repurchase $34.4 million of convertible notes - Investing.com

Dec 11, 2025
pulisher
Dec 11, 2025

Alnylam announces partial repurchase of 1.00% convertible senior notes due 2027 - marketscreener.com

Dec 11, 2025
pulisher
Dec 11, 2025

Alnylam Pharma Announces Convertible Notes Buyback - TipRanks

Dec 11, 2025
pulisher
Dec 11, 2025

Alnylam Announces Partial Repurchase Of 1.00% Convertible Senior Notes Due 2027 - TradingView — Track All Markets

Dec 11, 2025

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading
$862.05
price up icon 1.25%
$198.46
price down icon 1.10%
biotechnology ONC
$306.05
price up icon 0.57%
$749.79
price up icon 0.46%
$91.60
price down icon 0.68%
Cap:     |  Volume (24h):