445.12
price up icon3.56%   15.32
after-market After Hours: 445.12
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Alnylam Pharmaceuticals Inc stock is traded at $445.12, with a volume of 908.14K. It is up +3.56% in the last 24 hours and down -3.95% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
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Previous Close:
$429.80
Open:
$432.87
24h Volume:
908.14K
Relative Volume:
0.83
Market Cap:
$58.81B
Revenue:
$3.21B
Net Income/Loss:
$43.57M
P/E Ratio:
1,850.81
EPS:
0.2405
Net Cash Flow:
$221.36M
1W Performance:
-3.39%
1M Performance:
-3.95%
6M Performance:
+53.51%
1Y Performance:
+75.69%
1-Day Range:
Value
$430.27
$447.69
1-Week Range:
Value
$420.30
$467.73
52-Week Range:
Value
$205.87
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,230
Name
Twitter
@alnylam
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
445.12 56.78B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
432.17 109.05B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
784.61 82.75B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
917.63 56.52B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
204.51 44.58B 447.02M -1.18B -906.14M -6.1812

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
View All

Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
07:20 AM

Thanksgiving: Top 10 Most Innovative BioPharma Drugs In Phase 3 - Seeking Alpha

07:20 AM
pulisher
06:47 AM

A Look at Alnylam Pharmaceuticals's Valuation Following Raised Sales Guidance on Vutrisiran Outperformance - simplywall.st

06:47 AM
pulisher
Nov 26, 2025

Here’s What Boosted Alnylam Pharmaceuticals (ALNY) in Q3 - MSN

Nov 26, 2025
pulisher
Nov 26, 2025

Backdoor AI Beneficiary Yields 8.8%, Trades at 13% Discount - Investing.com

Nov 26, 2025
pulisher
Nov 25, 2025

MoA Mid Cap Growth Fund's Alnylam Pharmaceuticals Inc(ALNY) Holding History - GuruFocus

Nov 25, 2025
pulisher
Nov 24, 2025

Alnylam Pharmaceuticals (ALNY): Assessing Valuation After Recent Share Price Pullback - Yahoo Finance

Nov 24, 2025
pulisher
Nov 24, 2025

Is Alnylam Pharmaceuticals Stock Justified After 73.9% Surge and Clinical Trial Milestones? - simplywall.st

Nov 24, 2025
pulisher
Nov 24, 2025

Small Interfering RNA (siRNA) Therapeutics Market 2025: - openPR.com

Nov 24, 2025
pulisher
Nov 21, 2025

Here's How Much You Would Have Made Owning Alnylam Pharmaceuticals Stock In The Last 15 Years - Benzinga

Nov 21, 2025
pulisher
Nov 21, 2025

Alnylam's ATTR cardiomyopathy drug backed for NHS use - pharmaphorum

Nov 21, 2025
pulisher
Nov 21, 2025

NICE Final Draft Guidance backs Alnylam’s Amvuttra - The Pharma Letter

Nov 21, 2025
pulisher
Nov 21, 2025

Why Alnylam Pharmaceuticals Inc. (DUL) stock attracts wealthy investorsJuly 2025 Institutional & Expert Approved Trade Ideas - newser.com

Nov 21, 2025
pulisher
Nov 20, 2025

Alnylam Pharmaceuticals Faces Weak Start with 6.56% Gap Down Amid Market Concerns - Markets Mojo

Nov 20, 2025
pulisher
Nov 20, 2025

UK's drug-cost watchdog recommends Alnylam's heart disease drug - Reuters

Nov 20, 2025
pulisher
Nov 20, 2025

High-Flying Biotech Stock Sets Up After 96% Pop; Profitability In Sight As Key Drug Sales Double - MSN

Nov 20, 2025
pulisher
Nov 20, 2025

Is Alnylam Pharmaceuticals Inc. stock cheap at current valuationJuly 2025 Decliners & High Return Stock Watch Alerts - newser.com

Nov 20, 2025
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Nov 20, 2025

Will Alnylam Pharmaceuticals Inc. (DUL) stock sustain bullish trend into 2025 - newser.com

Nov 20, 2025
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Nov 20, 2025

Will Alnylam Pharmaceuticals Inc. stock deliver consistent dividendsTrade Analysis Report & Daily Growth Stock Investment Tips - newser.com

Nov 20, 2025
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Nov 20, 2025

Is Alnylam Pharmaceuticals Inc. stock a defensive play in 2025Weekly Profit Summary & Free Weekly Chart Analysis and Trade Guides - newser.com

Nov 20, 2025
pulisher
Nov 19, 2025

How Alnylam Pharmaceuticals Inc. (DUL) stock reacts to fiscal policiesWeekly Trading Summary & Real-Time Volume Analysis - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Regression analysis insights on Alnylam Pharmaceuticals Inc. performance2025 Top Gainers & Reliable Volume Spike Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Will Alnylam Pharmaceuticals Inc. continue its uptrendEarnings Miss & Smart Money Movement Tracker - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

VP Fitzgerald Sells 12,128 ($5.5M) Of Alnylam Pharmaceuticals Inc [ALNY] - TradingView

Nov 19, 2025
pulisher
Nov 19, 2025

[Form 4] ALNYLAM PHARMACEUTICALS, INC. Insider Trading Activity - Stock Titan

Nov 19, 2025
pulisher
Nov 19, 2025

How risky is Alnylam Pharmaceuticals Inc. (DUL) stock compared to peers2025 Top Decliners & Expert Approved Trade Ideas - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

How dovish Fed policy supports Alnylam Pharmaceuticals Inc. (DUL) stockQuarterly Profit Report & Reliable Intraday Trade Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Transcript : Alnylam Pharmaceuticals, Inc. Presents at Jefferies London Healthcare Conference 2025, Nov-19-2025 11 - MarketScreener

Nov 19, 2025
pulisher
Nov 19, 2025

Is Alnylam Pharmaceuticals Inc. (DUL) stock a fit for income portfolios2025 Price Targets & Smart Swing Trading Techniques - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

What data driven models say about Alnylam Pharmaceuticals Inc.’s futureVolume Spike & Fast Moving Stock Watchlists - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

How to recover losses in Alnylam Pharmaceuticals Inc. stockPortfolio Update Report & Verified Momentum Stock Alerts - newser.com

Nov 19, 2025

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$917.63
price down icon 0.03%
$204.51
price down icon 2.16%
biotechnology ONC
$340.64
price up icon 1.63%
$784.61
price down icon 0.34%
$102.70
price up icon 3.00%
Cap:     |  Volume (24h):