446.40
price down icon0.71%   -3.18
after-market After Hours: 446.40
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Alnylam Pharmaceuticals Inc stock is traded at $446.40, with a volume of 814.45K. It is down -0.71% in the last 24 hours and down -1.06% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
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Previous Close:
$449.58
Open:
$453.045
24h Volume:
814.45K
Relative Volume:
0.72
Market Cap:
$58.51B
Revenue:
$2.46B
Net Income/Loss:
$-319.09M
P/E Ratio:
-180.73
EPS:
-2.47
Net Cash Flow:
$-52.09M
1W Performance:
-1.58%
1M Performance:
-1.06%
6M Performance:
+65.82%
1Y Performance:
+62.58%
1-Day Range:
Value
$442.51
$453.05
1-Week Range:
Value
$442.51
$462.88
52-Week Range:
Value
$205.87
$484.21

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,230
Name
Twitter
@alnylam
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
446.40 58.93B 2.46B -319.09M -52.09M -2.47
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
385.74 97.91B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
563.90 58.88B 14.21B 4.46B 3.56B 39.68
Biotechnology icon
ARGX
Argen X Se Adr
711.62 43.52B 3.06B 1.28B 447.35M 21.30
Biotechnology icon
ONC
Beone Medicines Ltd Adr
326.06 36.11B 3.81B -644.79M -669.77M -6.24

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
View All

Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
Sep 26, 2025

$1000 Invested In Alnylam Pharmaceuticals 5 Years Ago Would Be Worth This Much Today - Benzinga

Sep 26, 2025
pulisher
Sep 26, 2025

RNA-Based Therapies Industry Analysis 2025 | Growth, USA Market - openPR.com

Sep 26, 2025
pulisher
Sep 25, 2025

Is Alnylam Pharmaceuticals (ALNY) an Undervalued Stock? - Yahoo

Sep 25, 2025
pulisher
Sep 25, 2025

Does Alnylam Pharmaceuticals (ALNY) Have the Potential to Generate Strong Long-Term Growth? - Yahoo Finance

Sep 25, 2025
pulisher
Sep 24, 2025

Cardiac Amyloidosis Pipeline 2025: Pioneering Clinical Developments by 20+ Global Leaders – DelveInsight | Featuring Eidos Therapeutics, Intellia Therapeutics, Novo Nordisk, Alnylam Pharmaceuticals - Barchart.com

Sep 24, 2025
pulisher
Sep 24, 2025

Why Alnylam Pharmaceuticals (ALNY) is a Top Momentum Stock for the Long-Term - Yahoo Finance

Sep 24, 2025
pulisher
Sep 24, 2025

Bannerman Wealth Management Group LLC Sells 565 Shares of Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 24, 2025
pulisher
Sep 24, 2025

IFM Investors Pty Ltd Acquires 1,508 Shares of Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 24, 2025
pulisher
Sep 24, 2025

Assenagon Asset Management S.A. Purchases 11,281 Shares of Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 24, 2025
pulisher
Sep 23, 2025

Swedbank AB Has $20.97 Million Stock Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 23, 2025
pulisher
Sep 23, 2025

Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target Raised to $500.00 at Royal Bank Of Canada - MarketBeat

Sep 23, 2025
pulisher
Sep 23, 2025

Pallas Capital Advisors LLC Decreases Stock Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 23, 2025
pulisher
Sep 23, 2025

Alnylam Pharmaceuticals (ALNY): Evaluating Valuation After FDA Tightens Drug Advertising Disclosure Rules - simplywall.st

Sep 23, 2025
pulisher
Sep 23, 2025

Alnylam at Bernstein Forum: Strategic Growth in RNAi Therapies - Investing.com

Sep 23, 2025
pulisher
Sep 23, 2025

Alnylam at Bernstein Forum: Strategic Growth in RNAi Therapies By Investing.com - Investing.com Canada

Sep 23, 2025
pulisher
Sep 23, 2025

Alnylam Pharmaceuticals, Inc. $ALNY Shares Purchased by Sumitomo Mitsui DS Asset Management Company Ltd - MarketBeat

Sep 23, 2025
pulisher
Sep 22, 2025

RNA-based Therapies Market to Reach USD 213.54 Billion by 2033, Driven by Rare Diseases, Oncology, and Advances in RNA Technologies | DataM Intelligence - PR Newswire

Sep 22, 2025
pulisher
Sep 22, 2025

With DTC ads under fire, pharma companies need to pivot - PharmaVoice

Sep 22, 2025
pulisher
Sep 22, 2025

U.S. Capital Wealth Advisors LLC Sells 3,984 Shares of Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 22, 2025
pulisher
Sep 22, 2025

Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target Raised to $520.00 - MarketBeat

Sep 22, 2025
pulisher
Sep 22, 2025

Gateway Investment Advisers LLC Decreases Stake in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 22, 2025
pulisher
Sep 21, 2025

Alnylam Pharmaceuticals (NASDAQ:ALNY) Price Target Raised to $566.00 at The Goldman Sachs Group - MarketBeat

Sep 21, 2025
pulisher
Sep 20, 2025

Aug Volume: Is Alnylam Pharmaceuticals Inc impacted by rising ratesQuarterly Profit Summary & Free Verified High Yield Trade Plans - خودرو بانک

Sep 20, 2025
pulisher
Sep 20, 2025

Nasdaq Moves: What’s the fair value of Alnylam Pharmaceuticals Inc. stock2025 Market Overview & Growth Oriented Trading Recommendations - خودرو بانک

Sep 20, 2025
pulisher
Sep 20, 2025

Does Alnylam's Entry Into the Genomics Alliance Hint at a New Era for Illumina (ILMN) R&D? - Yahoo Finance

Sep 20, 2025
pulisher
Sep 19, 2025

Swedbank AB Increases Stock Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 19, 2025
pulisher
Sep 19, 2025

Fed Meeting: Is Alnylam Pharmaceuticals Inc impacted by rising ratesEarnings Miss & AI Powered Buy and Sell Recommendations - خودرو بانک

Sep 19, 2025
pulisher
Sep 19, 2025

Performance Recap: Can Alnylam Pharmaceuticals Inc. be the next market leader2025 Top Gainers & Real-Time Chart Pattern Alerts - khodrobank.com

Sep 19, 2025
pulisher
Sep 19, 2025

Strs Ohio Makes New Investment in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 19, 2025
pulisher
Sep 19, 2025

Acadian Asset Management LLC Has $2.42 Million Stock Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 19, 2025
pulisher
Sep 19, 2025

RBC Capital Initiates Alnylam Pharmaceuticals(ALNY.US) With Buy Rating, Announces Target Price $500 - 富途牛牛

Sep 19, 2025
pulisher
Sep 19, 2025

Alnylam stock price target raised to $500 from $435 at RBC Capital - Investing.com India

Sep 19, 2025
pulisher
Sep 19, 2025

Alnylam Pharmaceuticals Completes Phase 1 Study of ALN-AGT01 RVR - TipRanks

Sep 19, 2025
pulisher
Sep 19, 2025

Moderna, Alnylam settle patent row over COVID vaccine delivery technology - MSN

Sep 19, 2025
pulisher
Sep 19, 2025

RBC Capital Raises Alnylam Pharmaceuticals (ALNY) Price Target t - GuruFocus

Sep 19, 2025
pulisher
Sep 19, 2025

Moderna (MRNA) Settles Patent Dispute with Alnylam - GuruFocus

Sep 19, 2025
pulisher
Sep 19, 2025

RBC Raises Price Target on Alnylam Pharmaceuticals to $500 From $435, Keeps Outperform Rating - MarketScreener

Sep 19, 2025
pulisher
Sep 19, 2025

Ascent Group LLC Makes New Investment in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 19, 2025
pulisher
Sep 19, 2025

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. Has $3.76 Million Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 19, 2025
pulisher
Sep 19, 2025

AG2R LA Mondiale Gestion D Actifs Buys New Shares in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Sep 19, 2025
pulisher
Sep 19, 2025

Growth Review: What are analysts price targets for Alnylam Pharmaceuticals IncJuly 2025 Levels & Free Weekly Watchlist of Top Performers - khodrobank.com

Sep 19, 2025
pulisher
Sep 18, 2025

Coagulation factor deficiency Market Analysis: Epidemiology Insights, Therapies, Companies, by DelveInsight | Novo Nordisk, Pfizer, Spark Therapeutics, Roche, Sanofi (Genzyme), Alnylam Pharmaceuticals - Barchart.com

Sep 18, 2025
pulisher
Sep 18, 2025

Moderna settles Alnylam patent lawsuits over COVID vaccine technology - ET Pharma

Sep 18, 2025
pulisher
Sep 18, 2025

Moderna settles Alnylam patent lawsuits over COVID vaccine technology | Business Information & News | FE - Westlaw Today

Sep 18, 2025
pulisher
Sep 18, 2025

Moderna, Alnylam Agree to End Vaccine-Delivery Patent Lawsuits - Bloomberg Law News

Sep 18, 2025
pulisher
Sep 18, 2025

Alnylam joins genomic alliance to advance RNA interference therapies - Investing.com India

Sep 18, 2025
pulisher
Sep 18, 2025

Alnylam joins Alliance for Genomic Discovery to advance RNAi therapeutics - Drug Discovery News

Sep 18, 2025
pulisher
Sep 18, 2025

Alnylam Pharmaceuticals joins Alliance for Genomic Discovery, expanding diverse clinical genomic dataset to drive precision medicine - The Malaysian Reserve

Sep 18, 2025
pulisher
Sep 18, 2025

Alnylam Pharmaceuticals joins Alliance for Genomic Discovery, ex - GuruFocus

Sep 18, 2025
pulisher
Sep 18, 2025

Alnylam Pharmaceuticals Insiders Sold US$12m Of Shares Suggesting Hesitancy - Yahoo Finance

Sep 18, 2025

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$563.90
price up icon 1.51%
$711.62
price up icon 0.07%
biotechnology ONC
$326.06
price down icon 0.81%
$137.03
price up icon 1.06%
$98.08
price up icon 0.00%
Cap:     |  Volume (24h):