loading
Alnylam Pharmaceuticals Inc stock is traded at $266.11, with a volume of 1.42M. It is up +0.61% in the last 24 hours and up +21.51% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
See More
Previous Close:
$264.50
Open:
$258.58
24h Volume:
1.42M
Relative Volume:
0.81
Market Cap:
$35.61B
Revenue:
$4.29B
Net Income/Loss:
$577.22M
P/E Ratio:
63.23
EPS:
4.2086
Net Cash Flow:
$641.34M
1W Performance:
+12.24%
1M Performance:
+21.51%
6M Performance:
-18.70%
1Y Performance:
-41.33%
1-Day Range:
Value
$258.02
$266.85
1-Week Range:
Value
$233.33
$271.19
52-Week Range:
Value
$197.81
$495.55

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,500
Name
Twitter
@alnylam
Name
Next Earnings Date
2026-10-29
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY vs VRTX, REGN, ARGX, MRNA, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
266.11 30.68B 4.29B 577.22M 641.34M 4.2086
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
546.12 136.93B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
827.72 85.11B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
1,033.15 64.95B 4.16B 1.29B 734.26M 19.58
MRNA icon
MRNA
Moderna Inc
145.55 53.23B 2.23B -3.19B -1.60B -8.1462
RVMD icon
RVMD
Revolution Medicines Inc
210.02 45.38B 742.00K -1.37B -1.07B -7.0731

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-16-26 Downgrade Jefferies Buy → Hold
Jan-28-26 Resumed Barclays Overweight
Jan-07-26 Resumed Oppenheimer Outperform
Aug-04-25 Upgrade Oppenheimer Perform → Outperform
Aug-04-25 Upgrade Wolfe Research Underperform → Peer Perform
Jul-30-25 Resumed Raymond James Outperform
Jul-21-25 Initiated Truist Buy
Mar-31-25 Initiated Redburn Atlantic Buy
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
View All

Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
Sep 06, 2026

Alnylam Pharmaceuticals (ALNY) Could Be 39% Undervalued On Fresh ESC 2026 Data - simplywall.st

Sep 06, 2026
pulisher
Sep 03, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY): Affordable Growth in Biotech - ChartMill

Sep 03, 2026
pulisher
Sep 02, 2026

ALNY Stock Climbs As Analysts Turn Bullish After ESC Data - StocksToTrade

Sep 02, 2026
pulisher
Sep 02, 2026

ALNY Stock Rebounds As Analysts Back RNAi Momentum - timothysykes.com

Sep 02, 2026
pulisher
Sep 02, 2026

ALNY Stock Rebounds As Analysts Back RNAi Growth Story - timothysykes.com

Sep 02, 2026
pulisher
Sep 02, 2026

Alnylam Pharmaceuticals Inc Stock (ALNY) Moved Up by 7.90% on Sep 2: Facts Behind the Movement - TradingKey

Sep 02, 2026
pulisher
Sep 02, 2026

Alnylam Pharmaceuticals gains as investors digest fresh ESC data and upcoming conference appearances - Quiver Quantitative

Sep 02, 2026
pulisher
Sep 02, 2026

Alnylam to Webcast Presentations at Upcoming September Investor Conferences - Business Wire

Sep 02, 2026
pulisher
Sep 02, 2026

ALNY Reiterated by HC Wainwright & Co. -- Price Target Maintained at $455 - GuruFocus

Sep 02, 2026
pulisher
Sep 01, 2026

Analysts Are Bullish on These Healthcare Stocks: Boston Scientific (BSX), Alnylam Pharma (ALNY) - The Globe and Mail

Sep 01, 2026
pulisher
Aug 31, 2026

Expanded RNAi Cardio Data Might Change The Case For Investing In Alnylam Pharmaceuticals (ALNY) - simplywall.st

Aug 31, 2026
pulisher
Aug 31, 2026

Alnylam Pharmaceuticals (ALNY) Investor Outlook: Exploring a 56% Potential Upside in Biotech Innovation - DirectorsTalk Interviews

Aug 31, 2026
pulisher
Aug 30, 2026

Alnylam data support Amvuttra across ATTR patient groups, advance hypertension drug case (ALNY:NASDAQ) - Seeking Alpha

Aug 30, 2026
pulisher
Aug 30, 2026

Alnylam Presents New Data at ESC Congress 2026 Reinforcing Strength in RNAi-Powered TTR Silencing Across ATTR-CM Patient Populations and Treatment Settings - Yahoo Finance

Aug 30, 2026
pulisher
Aug 28, 2026

If You Invested $100 In Alnylam Pharmaceuticals Stock 20 Years Ago, You Would Have This Much Today - Benzinga

Aug 28, 2026
pulisher
Aug 28, 2026

Alnylam drops as AstraZeneca posts full trial results for failed heart drug - Seeking Alpha

Aug 28, 2026
pulisher
Aug 27, 2026

Why Everyone Is Watching Alnylam Pharmaceuticals (ALNY) Today - simplywall.st

Aug 27, 2026
pulisher
Aug 26, 2026

ALNY INVESTOR ALERT: Kirby McInerney LLP Investigates Potential Claims Involving Alnylam Pharmaceuticals, Inc. - GlobeNewswire

Aug 26, 2026
pulisher
Aug 24, 2026

Alnylam to Present New Data Reinforcing Strength in RNAi-Powered TTR Silencing and Continued Progress in Hypertension at ESC Congress 2026 - Business Wire

Aug 24, 2026
pulisher
Aug 24, 2026

Alnylam Pharmaceuticals, Inc. (ALNY) Stock Analysis: A Biotech Leader with 56.72% Potential Upside - DirectorsTalk Interviews

Aug 24, 2026
pulisher
Aug 21, 2026

Why Amylyx Pharmaceuticals Blasted Nearly 79% Higher This Week - AOL.com

Aug 21, 2026
pulisher
Aug 21, 2026

Silvant Capital Management LLC Takes $5.46 Million Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Aug 21, 2026
pulisher
Aug 21, 2026

Wealthfront Advisers LLC Makes New Investment in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Aug 21, 2026
pulisher
Aug 21, 2026

NewEdge Wealth LLC Takes Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Aug 21, 2026
pulisher
Aug 21, 2026

Biotech Is Booming, But These 2 Stocks Missed the Memo - Sahm

Aug 21, 2026
pulisher
Aug 21, 2026

Danske Bank A S Takes $19.43 Million Position in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Aug 21, 2026
pulisher
Aug 20, 2026

Lowered TTR Sales Outlook And Legal Probe Might Change The Case For Investing In Alnylam (ALNY) - simplywall.st

Aug 20, 2026
pulisher
Aug 20, 2026

Bragar Eagel & Squire, P.C. is Investigating Alnylam - GlobeNewswire

Aug 20, 2026
pulisher
Aug 20, 2026

Securities Fraud Investigation Into Alnylam - GlobeNewswire

Aug 20, 2026
pulisher
Aug 20, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY) Upgraded to "Strong-Buy" at BMO Capital Markets - MarketBeat

Aug 20, 2026
pulisher
Aug 20, 2026

Alnylam Pharmaceuticals (NASDAQ:ALNY): A Value Stock Worthy of Investor Attention - ChartMill

Aug 20, 2026
pulisher
Aug 20, 2026

Mitsubishi UFJ Asset Management Co. Ltd. Makes New Investment in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Aug 20, 2026
pulisher
Aug 20, 2026

NewEdge Advisors LLC Trims Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Aug 20, 2026
pulisher
Aug 20, 2026

E Fund Management Co. Ltd. Acquires New Holdings in Alnylam Pharmaceuticals, Inc. $ALNY - MarketBeat

Aug 20, 2026
pulisher
Aug 20, 2026

(NASDAQ: ALNY): Investigation Launched Into Alnylam Pharmaceuticals, Inc. by Kessler Topaz Meltzer & Check, LLP - Barchart.com

Aug 20, 2026
pulisher
Aug 19, 2026

ALNY SHAREHOLDER ALERT: Alnylam Pharmaceuticals, Inc. Investors Encouraged to Contact Kirby McInerney LLP About Potential Securities Laws Violations - Business Wire

Aug 19, 2026
pulisher
Aug 19, 2026

Securities Fraud Investigation Into Alnylam Pharmaceuticals, Inc. (ALNY) Continues – Shareholders Who Lost Money Urged To Contact The Law Offices of Frank R. Cruz - WBOC TV

Aug 19, 2026
pulisher
Aug 19, 2026

NASDAQ: ALNY: Kessler Topaz Meltzer & Check, LLP Launches Investigation Into Alnylam Pharmaceuticals, Inc. - NewMediaWire

Aug 19, 2026
pulisher
Aug 19, 2026

Why Alnylam Pharmaceuticals (ALNY) Stock Is Up Today - Quiver Quantitative

Aug 19, 2026
pulisher
Aug 19, 2026

Alnylam initiated an outperform at BMO on RNAi pipeline - Seeking Alpha

Aug 19, 2026
pulisher
Aug 19, 2026

BMO Capital Markets Initiates Coverage on Alnylam Pharmaceuticals (NASDAQ:ALNY) - MarketBeat

Aug 19, 2026
pulisher
Aug 19, 2026

This Alnylam Pharmaceuticals Analyst Begins Coverage On A Bullish Note; Here Are Top 5 Initiations For We - Benzinga

Aug 19, 2026
pulisher
Aug 19, 2026

BMO initiates Alnylam stock with outperform on ATTR franchise growth By Investing.com - Investing.com Canada

Aug 19, 2026
pulisher
Aug 19, 2026

ALNY Initiated Coverage by BMO Capital -- Rating Set to Outperfo - GuruFocus

Aug 19, 2026
pulisher
Aug 18, 2026

Why the Alnylam Sell-Off Looks Overdone -- and What Investors Are Missing - AOL.com

Aug 18, 2026
pulisher
Aug 18, 2026

ALNY ALERT: Investigation Launched Into Alnylam Pharmaceuticals, Inc., Investors Are Encouraged to Contact KTMC Law Firm - NewMediaWire

Aug 18, 2026
pulisher
Aug 18, 2026

ALNY Looks 56.8% Undervalued on GF Value™ - GuruFocus

Aug 18, 2026
pulisher
Aug 17, 2026

Familial Amyloid Polyneuropathy Market - Future Market Insights

Aug 17, 2026
pulisher
Aug 17, 2026

ALNY Looks 56.7% Undervalued on GF Value™ - GuruFocus

Aug 17, 2026
pulisher
Aug 17, 2026

Alnylam Pharmaceuticals (ALNY): Investor Outlook With A 62.82% Potential Upside - DirectorsTalk Interviews

Aug 17, 2026
pulisher
Aug 17, 2026

ALNY Investor Alert: Kessler Topaz Meltzer & Check, LLP Encourages Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) Investors to Contact the Firm - The Globe and Mail

Aug 17, 2026

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading

Alnylam Pharmaceuticals Inc Stock (ALNY) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
PYOTT DAVID E I
Director
Jun 01 '26
Sale
299.18
3,830
1,145,853
1,582
ONC ONC
$358.26
price down icon 1.22%
$63.96
price up icon 0.13%
$126.29
price down icon 0.31%
$210.02
price down icon 0.40%
$103.76
price up icon 0.86%
Cap:     |  Volume (24h):