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Vertex Pharmaceuticals Inc stock is traded at $431.66, with a volume of 509.68K. It is down -0.84% in the last 24 hours and down -3.83% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$435.10
Open:
$431.89
24h Volume:
509.68K
Relative Volume:
0.37
Market Cap:
$109.77B
Revenue:
$12.07B
Net Income/Loss:
$3.95B
P/E Ratio:
28.15
EPS:
15.3349
Net Cash Flow:
$3.19B
1W Performance:
-2.21%
1M Performance:
-3.83%
6M Performance:
+2.39%
1Y Performance:
-12.39%
1-Day Range:
Value
$427.38
$433.68
1-Week Range:
Value
$427.38
$444.01
52-Week Range:
Value
$362.50
$510.77

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-05-04
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
431.54 110.67B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
745.45 80.98B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
779.91 49.00B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
303.96 41.87B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
300.28 33.28B 5.36B 287.73M 924.18M 2.5229

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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09:40 AM

Vertex Pharmaceuticals Incorporated (VRTX) PT Nudged Higher as RBC Updates Biotech Sector Outlook - Yahoo Finance

09:40 AM
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Apr 23, 2026

3 Healthcare Stocks With the Most Durable Competitive Moats - The Motley Fool

Apr 23, 2026
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Apr 22, 2026

Vertex Pharmaceuticals Inc. (VRTX)Bullish Jim Cramer Endorsement Highlights Divergent Sentiment Amid Mixed Pipeline UpdatesAsset Sale - Xã Thanh Hà

Apr 22, 2026
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Apr 22, 2026

Best Biotech Stocks To Watch TodayApril 22nd - MarketBeat

Apr 22, 2026
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Apr 22, 2026

Vertex Pharmaceuticals: Looking For Signs Of Success In Q1 Earnings (NASDAQ:VRTX) - Seeking Alpha

Apr 22, 2026
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Apr 21, 2026

Jim Cramer on Vertex Pharmaceuticals: “I Wish I Had Bought It for the Charitable Trust a Long Time Ago” - Insider Monkey

Apr 21, 2026
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Apr 21, 2026

Morgan Stanley Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Maintains Target Price $612 - Moomoo

Apr 21, 2026
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Apr 21, 2026

Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know - Yahoo Finance

Apr 21, 2026
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Apr 21, 2026

Halozyme Therapeutics Partners with Vertex for Hypercon Technology - HarianBasis.co

Apr 21, 2026
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Apr 21, 2026

Fierce Biotech Layoff Tracker 2026: Replimune reduces staff; Astellas shutters cell therapy site - Fierce Biotech

Apr 21, 2026
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Apr 20, 2026

Vertex Pharma stock (US92532F1003): Is the cystic fibrosis dominance now unlocking broader upside? - AD HOC NEWS

Apr 20, 2026
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Apr 20, 2026

Vertex Pharma stock (US92532F1003): Is its cystic fibrosis dominance strong enough to unlock new ups - AD HOC NEWS

Apr 20, 2026
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Apr 19, 2026

2 Under-the-Radar Biotech Stocks Worth Buying for the Long Term - The Motley Fool

Apr 19, 2026
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Apr 18, 2026

Vertex Pharmaceuticals Experiences Evaluation Revision Amid Mixed Market Performance Indicators - Markets Mojo

Apr 18, 2026
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Apr 18, 2026

GF Fund Management CO. LTD. Raises Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 18, 2026
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Apr 18, 2026

Vertex Pharmaceuticals Incorporated $VRTX Stock Position Lifted by Asset Management One Co. Ltd. - MarketBeat

Apr 18, 2026
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Apr 17, 2026

Morgan Stanley Lifts Vertex Pharmaceuticals (VRTX) PT on Updated Biopharma Models - Insider Monkey

Apr 17, 2026
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Apr 17, 2026

Cramer's lightning round: Buy Vertex Pharmaceuticals - MSN

Apr 17, 2026
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Apr 17, 2026

Lightning round: Buy Vertex Pharmaceuticals - MSN

Apr 17, 2026
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Apr 17, 2026

Lightning Round: Buy Vertex Pharmaceuticals - CNBC

Apr 17, 2026
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Apr 17, 2026

Vertex Pharmaceuticals (VRTX) Beats Stock Market Upswing: What Investors Need to Know - Yahoo Finance

Apr 17, 2026
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Apr 17, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Apr 17, 2026
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Apr 17, 2026

Vertex (VRTX) director receives new deferred stock unit grant - Stock Titan

Apr 17, 2026
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Apr 17, 2026

VRTX Stock Quote Price and Forecast - CNN

Apr 17, 2026
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Apr 17, 2026

Vertex (NASDAQ: VRTX) director granted 107 deferred stock units as equity pay - Stock Titan

Apr 17, 2026
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Apr 17, 2026

Vertex (VRTX) board member receives deferred stock unit award - Stock Titan

Apr 17, 2026
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Apr 17, 2026

Vertex Pharma stock (US92532F1003): Is cystic fibrosis dominance still enough for long-term upside? - AD HOC NEWS

Apr 17, 2026
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Apr 17, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Acquired by Mirae Asset Global Investments Co. Ltd. - MarketBeat

Apr 17, 2026
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Apr 17, 2026

KBC Group NV Acquires 7,518 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 17, 2026
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Apr 16, 2026

Vertex Pharmaceuticals (VRTX) Stock Slides as Market Rises: Facts to Know Before You Trade - Yahoo Finance

Apr 16, 2026
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Apr 16, 2026

Vertex’s IgAN drug outlook strengthens on positive phase 3 data - S&P Global

Apr 16, 2026
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Apr 16, 2026

Vertex Pharmaceuticals Inc. stock underperforms Thursday when compared to competitors - MarketWatch

Apr 16, 2026
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Apr 16, 2026

Is Vertex Pharmaceuticals' Empire in Trouble? - AOL.com

Apr 16, 2026
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Apr 16, 2026

Vertex Pharmaceuticals Incorporated : 2025 Data Summary - marketscreener.com

Apr 16, 2026
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Apr 16, 2026

Vertex price returns lowerForecast today16-04-2026 - Economies.com

Apr 16, 2026
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Apr 16, 2026

Morgan Stanley Keeps Their Buy Rating on Vertex Pharmaceuticals (VRTX) - The Globe and Mail

Apr 16, 2026
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Apr 16, 2026

Lbp Am Sa Acquires 22,918 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 16, 2026
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Apr 16, 2026

Vertex Pharmaceuticals Inc (STU:VX1) Stock Price & 30 Year Financial Data - GuruFocus

Apr 16, 2026
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Apr 15, 2026

Vertex Pharmaceuticals: Solid CF Franchise and Emerging Pipeline Support Buy Rating and Premium Valuation - TipRanks

Apr 15, 2026
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Apr 15, 2026

Zealand Pharma appoints US-based investor relations head - medwatch.com

Apr 15, 2026
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Apr 15, 2026

5 biopharma M&A deals where the workforce was the prize - BioSpace

Apr 15, 2026
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Apr 14, 2026

Vertex Sues Former Exec To Block Move To Rival - Law360

Apr 14, 2026
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Apr 14, 2026

Baillie Gifford Trims Vertex Pharmaceuticals Stake - National Today

Apr 14, 2026
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Apr 14, 2026

15,717 Shares in Vertex Pharmaceuticals Incorporated $VRTX Bought by Third View Private Wealth LLC - MarketBeat

Apr 14, 2026
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Apr 14, 2026

Massachusetts Financial Services Co. MA Sells 291,226 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 14, 2026
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Apr 14, 2026

Baillie Gifford & Co. Has $91.17 Million Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 14, 2026
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Apr 13, 2026

Argenx and Vertex Pharmaceuticals named BofA top biotech picks for 2026 - Investing.com UK

Apr 13, 2026
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Apr 13, 2026

Hardman Johnston Global Advisors LLC Sells 15,346 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 13, 2026
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Apr 13, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Bought by Andrew Hill Investment Advisors Inc. - MarketBeat

Apr 13, 2026
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Apr 12, 2026

Sumitomo Mitsui Trust Group Reduces Vertex Pharmaceuticals Stake - National Today

Apr 12, 2026
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Apr 12, 2026

Robeco Institutional Asset Management B.V. Raises Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 12, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$745.42
price down icon 2.72%
$781.05
price down icon 0.89%
$303.96
price down icon 3.13%
ONC ONC
$300.23
price up icon 0.27%
$135.94
price down icon 5.19%
Cap:     |  Volume (24h):