450.41
price down icon0.58%   -2.65
after-market After Hours: 448.00 -2.41 -0.54%
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Vertex Pharmaceuticals Inc stock is traded at $450.41, with a volume of 1.08M. It is down -0.58% in the last 24 hours and up +1.38% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$453.06
Open:
$453.64
24h Volume:
1.08M
Relative Volume:
0.81
Market Cap:
$114.32B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
26.70
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
+5.98%
1M Performance:
+1.38%
6M Performance:
+3.03%
1Y Performance:
+6.95%
1-Day Range:
Value
$447.36
$456.68
1-Week Range:
Value
$421.11
$456.68
52-Week Range:
Value
$362.50
$507.92

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-05-04
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
450.41 114.99B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
712.87 75.47B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
822.13 49.92B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
293.45 38.92B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
149.47 31.88B 742.00K -1.37B -1.07B -7.0731

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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11:08 AM

Vertex Pharmaceuticals stock (US92532F1003): Shareholder approval fuels biotech momentum - AD HOC NEWS

11:08 AM
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09:29 AM

Vertex Pharma stock (US92532F1003): Shares up 1.06% to $453 amid biotech strength - AD HOC NEWS

09:29 AM
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May 13, 2026

Vertex Pharmaceuticals (VRTX) Announces Approval of 2026 Stock a - GuruFocus

May 13, 2026
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May 13, 2026

5 Must-Read Analyst Questions From Vertex Pharmaceuticals’s Q1 Earnings Call - Yahoo Finance

May 13, 2026
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May 13, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

May 13, 2026
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May 13, 2026

Vertex Pharma stock (US92532F1003): Rockets 3.77% on strong options volume - AD HOC NEWS

May 13, 2026
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May 12, 2026

Carmen Bozic sells 2,329 VRTX shares on 02/27, 03/13 and 03/27 (VRTX) - Stock Titan

May 12, 2026
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May 12, 2026

Why is Vertex Pharmaceuticals stock rallying today? - Investing.com

May 12, 2026
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May 12, 2026

Why is Vertex Pharmaceuticals stock rallying today? By Investing.com - Investing.com Canada

May 12, 2026
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May 12, 2026

Vertex Pharma stock (US92532F1003): Earnings highlight pain drug advances - AD HOC NEWS

May 12, 2026
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May 12, 2026

Vertex’s Germany CASGEVY Deal Highlights Growing Non CF Growth Story - Yahoo Finance

May 12, 2026
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May 12, 2026

A year after Vertex’s big launch, pain drug research faces a pivotal moment - BioPharma Dive

May 12, 2026
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May 11, 2026

1 Top Wall Street Analyst Thinks CRISPR Therapeutics Could More Than Double. Should You Buy the Stock Hand Over Fist? - The Motley Fool

May 11, 2026
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May 11, 2026

Vertex to Participate in Upcoming May Investor Conferences - Business Wire

May 11, 2026
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May 11, 2026

Vertex Pharma stock (US92532F1003): Latest developments and business overview - AD HOC NEWS

May 11, 2026
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May 10, 2026

Top Biotech Stocks To ConsiderMay 10th - MarketBeat

May 10, 2026
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May 09, 2026

Vertex Pharmaceuticals Incorporated (VRTX) Latest Stock News & Headlines - Yahoo Finance

May 09, 2026
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May 09, 2026

Investors heavily search Vertex Pharmaceuticals Incorporated (VRTX): Here is what you need to know - MSN

May 09, 2026
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May 09, 2026

Biotech Stocks To Watch NowMay 9th - MarketBeat

May 09, 2026
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May 09, 2026

Vertex Pharma stock (US92532F1003): Q1 2026 earnings beat lifts shares on growth in new disease area - AD HOC NEWS

May 09, 2026
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May 09, 2026

Vertex Pharmaceuticals Earnings Call Highlights New Growth Engines - TipRanks

May 09, 2026
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May 08, 2026

Vertex Pharmaceuticals Q2 2026 earnings preview - MSN

May 08, 2026
pulisher
May 08, 2026

Vertex Pharmaceuticals (NQ: VRTX - FinancialContent

May 08, 2026
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May 08, 2026

VRTX's Alyftrek, Journavx & Casgevy See Strong Momentum in Q1 Earnings - Yahoo Finance

May 08, 2026
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May 08, 2026

Vertex Pharma stock (US92532F1003): Mixed Q1 results and 2026 guidance reiterated - AD HOC NEWS

May 08, 2026
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May 08, 2026

Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know - Yahoo Finance

May 08, 2026
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May 08, 2026

Vertex Pharmaceuticals (VRTX) Secures Reimbursement Agreement fo - GuruFocus

May 08, 2026
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May 08, 2026

April 2026 — CDMO Opportunities And Threats Report - Bioprocess Online

May 08, 2026
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May 07, 2026

Vertex's New Big Pharma Partners - Yahoo

May 07, 2026
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May 07, 2026

Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Just Released Its First-Quarter Results And Analysts Are Updating Their Estimates - Yahoo Finance

May 07, 2026
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May 07, 2026

Vertex Pharmaceuticals Stock Analysis: 1991 IPO Growth and 2026 OutlookNews and Statistics - IndexBox

May 07, 2026
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May 07, 2026

VRTX Technical Analysis | Trend, Signals & Chart Patterns | VERTEX PHARMACEUTICALS INC (NASDAQ:VRTX) - ChartMill

May 07, 2026
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May 06, 2026

Vertex (VRTX) Q1 2026 Earnings Call Transcript - AOL.com

May 06, 2026
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May 06, 2026

Vertex Pharmaceuticals | 144: Notice of proposed sale of securities pursuant to Rule 144 - Moomoo

May 06, 2026
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May 06, 2026

Vertex Pharmaceuticals (NASDAQ: VRTX) affiliate proposes stock sales; insider sales listed - Stock Titan

May 06, 2026
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May 06, 2026

Vertex Pharmaceuticals Q1 Earnings Review: Pharma May Need Bolder M&A Strategy (VRTX) - Seeking Alpha

May 06, 2026
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May 06, 2026

Michel Lagarde At Vertex Pharmaceuticals Acquires Stock Options Worth $9K - Benzinga

May 06, 2026
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May 06, 2026

BRUCE SACHS Backs Up Beliefs With A Notable Acquisition Of Vertex Pharmaceuticals Stock Options Worth $9K - Benzinga

May 06, 2026
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May 06, 2026

Vertex Pharmaceuticals Posts Mixed Q1; Investors Focus On Non-CF Pipeline For Growth - Sahm

May 06, 2026
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May 06, 2026

German reimbursement deal for Vertex’ Casgevy - The Pharma Letter

May 06, 2026
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May 06, 2026

Analysts Offer Insights on Healthcare Companies: Editas Medicine (EDIT), Vertex Pharmaceuticals (VRTX) and Sotera Health (SHC) - The Globe and Mail

May 06, 2026
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May 06, 2026

Vertex Announces CASGEVY® Reimbursement Agreement for the Treatment of Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia in Germany - BioSpace

May 06, 2026
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May 06, 2026

Vertex secures German reimbursement deal for gene therapy By Investing.com - Investing.com Canada

May 06, 2026
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May 06, 2026

Vertex secures German reimbursement deal for gene therapy - Investing.com

May 06, 2026
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May 06, 2026

Analysts Offer Insights on Healthcare Companies: Axsome Therapeutics (AXSM), Vertex Pharmaceuticals (VRTX) and Merck & Company (MRK) - The Globe and Mail

May 06, 2026
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May 06, 2026

Germany backs access to Vertex's one-time gene therapy for blood disorders - Stock Titan

May 06, 2026
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May 06, 2026

Is It Too Late To Consider Vertex Pharmaceuticals (VRTX) After Recent Share Price Weakness - Yahoo Finance

May 06, 2026
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May 06, 2026

Vertex Pharmaceuticals: Investment Returns and Future Outlook - Intellectia AI

May 06, 2026
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May 06, 2026

Is This Millionaire-Maker Biotech Stock a Buy Right Now? - The Motley Fool

May 06, 2026
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May 06, 2026

Vertex Pharmaceuticals Incorporated 2026 Q1ResultsEarnings Call Presentation (NASDAQ:VRTX) 2026-05-06 - Seeking Alpha

May 06, 2026
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May 05, 2026

Insider Sell: Sangeeta Bhatia Sells Shares of Vertex Pharmaceuti - GuruFocus

May 05, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$712.87
price down icon 0.97%
$822.13
price up icon 2.46%
$293.45
price up icon 0.56%
$149.47
price down icon 0.31%
ONC ONC
$304.62
price down icon 3.61%
Cap:     |  Volume (24h):