548.05
price up icon1.44%   7.79
after-market After Hours: 548.05
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Vertex Pharmaceuticals Inc stock is traded at $548.05, with a volume of 1.07M. It is up +1.44% in the last 24 hours and up +13.70% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$540.26
Open:
$545.1
24h Volume:
1.07M
Relative Volume:
0.70
Market Cap:
$138.91B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
32.49
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
+8.36%
1M Performance:
+13.70%
6M Performance:
+14.92%
1Y Performance:
+37.89%
1-Day Range:
Value
$540.70
$555.32
1-Week Range:
Value
$502.53
$555.32
52-Week Range:
Value
$374.17
$555.32

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-08-03
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, MRNA, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
548.05 136.93B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
834.04 85.11B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
1,039.78 64.95B 4.16B 1.29B 734.26M 19.58
MRNA icon
MRNA
Moderna Inc
145.13 53.23B 2.23B -3.19B -1.60B -8.1462
RVMD icon
RVMD
Revolution Medicines Inc
209.46 45.38B 742.00K -1.37B -1.07B -7.0731

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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Aug 21, 2026

Vertex Pharmaceuticals: A Biotech Cash Cow With Pipeline Upside? - The Globe and Mail

Aug 21, 2026
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Aug 21, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Aug 21, 2026
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Aug 21, 2026

Uber, ServiceNow And A Health Care Stock On CNBC’s ‘Final Trades’ - Benzinga

Aug 21, 2026
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Aug 21, 2026

IBBQ vs. PBE: Which Biotech ETF Is the Better Buy? - The Motley Fool

Aug 21, 2026
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Aug 21, 2026

Why Is Vertex Pharmaceuticals (NASDAQ:VRTX) Pipeline Value in Focus? - Kalkine Media

Aug 21, 2026
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Aug 21, 2026

Vise Technologies Inc. Makes New Investment in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 21, 2026
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Aug 21, 2026

Trillium Asset Management LLC Acquires New Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 21, 2026
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Aug 21, 2026

PCM Encore LLC Invests $1.06 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 21, 2026
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Aug 21, 2026

B. Metzler seel. Sohn & Co. AG Acquires Shares of 231,381 Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 21, 2026
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Aug 21, 2026

Bank of New York Mellon Corp Purchases Shares of 1,672,623 Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 21, 2026
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Aug 20, 2026

Vertex Pharmaceuticals Reinforces Dominance in Cystic Fibrosis Market as Competitor Falters - SSBCrack

Aug 20, 2026
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Aug 20, 2026

Vertex Pharmaceuticals' Rally Has a New Engine -- and Wall Street Thinks the Best Is Still Ahead - AOL.com

Aug 20, 2026
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Aug 20, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) Enters New Healthcare Focus - Kalkine Media

Aug 20, 2026
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Aug 20, 2026

Vertex Pharmaceuticals Inc. stock underperforms Thursday when compared to competitors - MarketWatch

Aug 20, 2026
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Aug 20, 2026

Vertex Pharmaceuticals (VRTX) Q1 2026 Earnings Call Transcript - Fortune

Aug 20, 2026
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Aug 20, 2026

Madison Asset Management LLC Takes Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 20, 2026
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Aug 20, 2026

Somerville Kurt F Invests $8.17 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 20, 2026
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Aug 20, 2026

Westport Asset Management Inc. Purchases New Shares in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 20, 2026
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Aug 20, 2026

8,423 Shares in Vertex Pharmaceuticals Incorporated $VRTX Acquired by Notis McConarty Edward - MarketBeat

Aug 20, 2026
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Aug 20, 2026

Puzo Michael J Purchases Shares of 15,907 Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 20, 2026
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Aug 20, 2026

11,305 Shares in Vertex Pharmaceuticals Incorporated $VRTX Acquired by NewEdge Wealth LLC - MarketBeat

Aug 20, 2026
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Aug 20, 2026

Knuff & Co LLC Purchases New Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 20, 2026
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Aug 20, 2026

DCF Advisers LLC Invests $5.71 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 20, 2026
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Aug 20, 2026

Vertex Pharmaceuticals Inc Stock Price Live, Charts & News - The Economic Times

Aug 20, 2026
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Aug 20, 2026

AssuredPartners Investment Advisors LLC Invests $2.06 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 20, 2026
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Aug 20, 2026

Are Wall Street Analysts Bullish on Vertex Stock? - Barchart.com

Aug 20, 2026
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Aug 19, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Closed Up by 4.48% on Aug 19: Drivers Behind the Movement - TradingKey

Aug 19, 2026
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Aug 19, 2026

Crinetics (CRNX) projects $1B+ 2030 revenue for Vertex deal - Stock Titan

Aug 19, 2026
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Aug 19, 2026

What Is Putting Vertex Pharmaceuticals (NASDAQ:VRTX) Under the Spotlight? - Kalkine Media

Aug 19, 2026
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Aug 19, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) Sets New 1-Year HighHere's What Happened - MarketBeat

Aug 19, 2026
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Aug 19, 2026

Vertex Pharmaceuticals stock hits all-time high at 546.17 USD - Investing.com

Aug 19, 2026
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Aug 19, 2026

Vertex Pharmaceuticals stock hits all-time high at 546.17 USD By Investing.com - Investing.com South Africa

Aug 19, 2026
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Aug 19, 2026

0000875320-22-000017 | 8-K - Vertex Pharmaceuticals Newsroom

Aug 19, 2026
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Aug 19, 2026

Wealthfront Advisers LLC Purchases New Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 19, 2026
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Aug 19, 2026

Meeder Advisory Services Inc. Buys Shares of 6,415 Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 19, 2026
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Aug 19, 2026

Pallas Capital Advisors LLC Takes $1.09 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 19, 2026
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Aug 19, 2026

Danske Bank A S Takes $78.52 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 19, 2026
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Aug 19, 2026

27,829 Shares in Vertex Pharmaceuticals Incorporated $VRTX Acquired by Danica Pension Livsforsikringsaktieselskab - MarketBeat

Aug 19, 2026
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Aug 19, 2026

Vertex Pharma stock holds at record levels as analysts highlight competitive win - Ad-hoc-news.de

Aug 19, 2026
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Aug 18, 2026

BMO Capital Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Maintains Target Price $600 - Moomoo

Aug 18, 2026
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Aug 18, 2026

Bernstein Names Top Biotech Stock Pick: Vertex Leads After Rival Drug Fails - Investing.com Nigeria

Aug 18, 2026
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Aug 18, 2026

Vertex Pharmaceuticals Inc. stock underperforms Tuesday when compared to competitors despite daily gains - MarketWatch

Aug 18, 2026
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Aug 18, 2026

UNIVEST FINANCIAL Corp Takes Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 18, 2026
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Aug 18, 2026

Perigon Wealth Management LLC Takes $4.39 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 18, 2026
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Aug 18, 2026

Mitsubishi UFJ Asset Management Co. Ltd. Acquires New Shares in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 18, 2026
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Aug 18, 2026

Citizens Financial Group Inc. RI Purchases New Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 18, 2026
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Aug 18, 2026

Cornerstone Advisors LLC Purchases New Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 18, 2026
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Aug 18, 2026

6,857 Shares in Vertex Pharmaceuticals Incorporated $VRTX Bought by Commerzbank Aktiengesellschaft FI - MarketBeat

Aug 18, 2026
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Aug 18, 2026

Deutsche Bank AG Invests $784.39 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 18, 2026
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Aug 18, 2026

BlackRock Inc. Invests $11.98 Billion in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Aug 18, 2026
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Aug 18, 2026

Fierce Biotech Layoff Tracker 2026: Kolon cuts workforce after ph. 3 fail; Sanofi sheds 229 staffers - Fierce Biotech

Aug 18, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$834.04
price up icon 0.90%
$1,039.78
price up icon 0.16%
$145.13
price up icon 8.86%
$209.46
price down icon 1.07%
ONC ONC
$374.47
price up icon 1.44%
Cap:     |  Volume (24h):