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Vertex Pharmaceuticals Inc stock is traded at $469.34, with a volume of 1.10M. It is down -1.84% in the last 24 hours and down -4.50% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$478.13
Open:
$481.79
24h Volume:
1.10M
Relative Volume:
0.76
Market Cap:
$119.23B
Revenue:
$12.07B
Net Income/Loss:
$3.95B
P/E Ratio:
30.61
EPS:
15.3349
Net Cash Flow:
$3.19B
1W Performance:
+2.77%
1M Performance:
-4.50%
6M Performance:
+18.96%
1Y Performance:
-6.68%
1-Day Range:
Value
$469.08
$486.66
1-Week Range:
Value
$450.78
$507.92
52-Week Range:
Value
$362.50
$519.68

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-02-12
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
469.34 119.23B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
745.77 78.84B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
700.45 43.35B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
313.41 41.57B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
284.05 31.51B 5.36B 287.73M 924.18M 2.5229

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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Mar 14, 2026

Prosight Management LP Boosts Vertex Pharmaceuticals Stake - National Today

Mar 14, 2026
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Mar 13, 2026

Insider Sell: Duncan Mckechnie Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Mar 13, 2026
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Mar 13, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors despite losses on the day - MarketWatch

Mar 13, 2026
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Mar 13, 2026

What Vertex Pharmaceuticals (VRTX)'s IgA Nephropathy Win Means For Its Next Major Franchise Potential - simplywall.st

Mar 13, 2026
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Mar 13, 2026

Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It - Yahoo Finance

Mar 13, 2026
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Mar 13, 2026

Quadrature Capital Ltd Boosts Vertex Pharmaceuticals Stake - National Today

Mar 13, 2026
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Mar 13, 2026

Vertex Pharmaceuticals Inc (NASDAQ:VRTX) Merges Strong Fundamentals with Bullish Technical Setup - ChartMill

Mar 13, 2026
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Mar 12, 2026

2 Factors to Consider Investing in VRTX and 1 Reason to Remain Careful - Bitget

Mar 12, 2026
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Mar 12, 2026

Vertex Pharmaceuticals Inc. stock underperforms Thursday when compared to competitors - MarketWatch

Mar 12, 2026
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Mar 12, 2026

Is Vertex Pharmaceuticals (VRTX) Pricing In Too Much Optimism After Recent Share Gains? - simplywall.st

Mar 12, 2026
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Mar 12, 2026

VRTX SEC FilingsVertex Pharmaceuticals Inc 10-K, 10-Q, 8-K Forms - Stock Titan

Mar 12, 2026
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Mar 12, 2026

Vertex Pharmaceuticals (VRTX) Sees Target Price Raised by Truist Securities | VRTX Stock News - GuruFocus

Mar 12, 2026
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Mar 12, 2026

Connor Clark & Lunn Investment Management Ltd. Acquires 14,706 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 12, 2026
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Mar 12, 2026

CreativeOne Wealth LLC Trims Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 12, 2026
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Mar 12, 2026

Vertex Pharma (NASDAQ:VRTX) Market Focus Builds Across Nasdaq Index - Kalkine Media

Mar 12, 2026
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Mar 11, 2026

Vertex Pharmaceuticals (VRTX) Registers a Bigger Fall Than the Market: Important Facts to Note - Yahoo! Finance Canada

Mar 11, 2026
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Mar 11, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) Stock Price Expected to Rise, Truist Financial Analyst Says - MarketBeat

Mar 11, 2026
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Mar 11, 2026

Stocks making big moves yesterday: nLIGHT, Myriad Genetics, Vertex Pharmaceuticals, Nextpower, and Teladoc - Yahoo Finance

Mar 11, 2026
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Mar 11, 2026

Vertex Pharmaceuticals Shares Sold by Schroder Investment Management - National Today

Mar 11, 2026
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Mar 11, 2026

Vertex (VRTX) Moves 8.3% Higher: Will This Strength Last? - Yahoo Finance

Mar 11, 2026
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Mar 11, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Sold by Schroder Investment Management Group - MarketBeat

Mar 11, 2026
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Mar 11, 2026

Van ECK Associates Corp Has $58.38 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 11, 2026
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Mar 11, 2026

Vertex preps FDA filing for IgAN drug after phase 3 readout - pharmaphorum

Mar 11, 2026
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Mar 11, 2026

S&P 500 Dips 0.21% as Vertex Pharmaceuticals Soars 8.31% Amid Market Struggles - Markets Mojo

Mar 11, 2026
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Mar 11, 2026

Scotiabank Reaffirms Their Buy Rating on Vertex Pharmaceuticals (VRTX) - The Globe and Mail

Mar 11, 2026
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Mar 11, 2026

Analysts Are Bullish on These Healthcare Stocks: Atai Beckley N.V. (ATAI), BridgeBio Oncology Therapeutics (BBOT) - The Globe and Mail

Mar 11, 2026
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Mar 11, 2026

Richard Bernstein Advisors LLC Sells 4,059 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 11, 2026
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Mar 11, 2026

Wall Street Analysts Are Neutral on Top Healthcare Picks - The Globe and Mail

Mar 11, 2026
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Mar 11, 2026

DE Burlo Group Inc. Sells 43,740 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 11, 2026
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Mar 11, 2026

Vertex Kidney Trial Success Opens Door To New Autoimmune Franchise - simplywall.st

Mar 11, 2026
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Mar 11, 2026

Blair William & Co. IL Reduces Vertex Pharmaceuticals Stake - National Today

Mar 11, 2026
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Mar 11, 2026

Bank of Montreal Boosts Vertex Pharmaceuticals Holdings by 15.5% - National Today

Mar 11, 2026
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Mar 11, 2026

Vertex Pharmaceuticals Joins Elite List Of Stocks With 95-Plus Composite Rating - Investor's Business Daily

Mar 11, 2026
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Mar 11, 2026

Bank of Montreal Can Has $164.28 Million Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 11, 2026
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Mar 10, 2026

Narrow-Moat Vertex's Positive Data for Povetacicept Support Diversification Beyond Core CF Franchise - Morningstar

Mar 10, 2026
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Mar 10, 2026

Why Vertex Pharmaceuticals (VRTX) Stock Is Up Today - Yahoo Finance

Mar 10, 2026
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Mar 10, 2026

Vertex Pops On 'Remarkable' Results For Chronic Kidney Disease Drug - Investor's Business Daily

Mar 10, 2026
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Mar 10, 2026

Vertex Pharmaceuticals Stock Jumps with Positive Drug Pipeline News - timothysykes.com

Mar 10, 2026
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Mar 10, 2026

Vertex Pharmaceuticals Hits Milestone with Povetacicept Data, Shares Surge - StocksToTrade

Mar 10, 2026
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Mar 10, 2026

These Stocks Are Today’s Movers: BioNTech, NIO, Centene, Vertex, Paramount, Rivian, Occidental, and More - Barron's

Mar 10, 2026
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Mar 10, 2026

Vertex Just Reported Trial Results for a Kidney Drug. What It Means for the Stock. - Barron's

Mar 10, 2026
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Mar 10, 2026

Vertex Pharmaceuticals (VRTX) Receives Rating Update and Price T - GuruFocus

Mar 10, 2026
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Mar 10, 2026

Key facts: Vertex Pharmaceuticals reports positive trial results; firms raise price targets - TradingView

Mar 10, 2026
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Mar 10, 2026

Here’s Why Vertex Pharmaceuticals Stock (VRTX) Is Up 10% Today - TipRanks

Mar 10, 2026
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Mar 10, 2026

Vertex Pharma to Seek Speedy FDA Approval for Kidney Disease Drug From $4.9B Acquisition - MedCity News

Mar 10, 2026
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Mar 10, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Moved Up by 8.03% on Mar 10: What Signal Does It Send? - TradingKey

Mar 10, 2026
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Mar 10, 2026

Vertex Pharma Stock Rises on IgA Nephropathy Drug Trial Success | 2026News and Statistics - IndexBox

Mar 10, 2026
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Mar 10, 2026

Vertex to seek approval of IgAN drug after Phase III success - Clinical Trials Arena

Mar 10, 2026
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Mar 10, 2026

Vertex Pharmaceuticals Soars on Promising Phase 3 Trial Results for Povetacicept - GuruFocus

Mar 10, 2026
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Mar 10, 2026

Vertex Pharmaceuticals (NASDAQ:VRTX) Given New $596.00 Price Target at Morgan Stanley - MarketBeat

Mar 10, 2026
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Mar 10, 2026

VRTX Stock Gains on Upbeat Interim Data From Kidney Disease Drug Study - Finviz

Mar 10, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$745.77
price down icon 0.11%
$700.45
price down icon 1.19%
$313.41
price down icon 1.20%
biotechnology ONC
$284.05
price down icon 0.44%
$139.50
price down icon 0.01%
Cap:     |  Volume (24h):