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Vertex Pharmaceuticals Inc stock is traded at $438.71, with a volume of 1.24M. It is down -1.91% in the last 24 hours and down -9.74% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$447.26
Open:
$447.55
24h Volume:
1.24M
Relative Volume:
0.85
Market Cap:
$111.45B
Revenue:
$12.07B
Net Income/Loss:
$3.95B
P/E Ratio:
28.61
EPS:
15.3349
Net Cash Flow:
$3.19B
1W Performance:
-3.31%
1M Performance:
-9.74%
6M Performance:
+7.30%
1Y Performance:
-9.26%
1-Day Range:
Value
$436.56
$449.62
1-Week Range:
Value
$431.01
$453.98
52-Week Range:
Value
$362.50
$510.77

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-02-12
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, INSM

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
438.71 111.45B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
761.85 80.54B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
746.42 46.32B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
318.85 42.29B 3.71B 313.75M 465.38M 2.2571
INSM icon
INSM
Insmed Inc
162.43 35.01B 606.42M -1.28B -997.58M -6.403

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

pulisher
Apr 03, 2026

Insider Sell: Joy Liu Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Apr 03, 2026
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Apr 03, 2026

Insider Selling: Vertex Pharmaceuticals (NASDAQ:VRTX) EVP Sells $439,288.26 in Stock - MarketBeat

Apr 03, 2026
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Apr 03, 2026

Vertex (VRTX) legal chief sells 978 shares under 10b5-1 plan - Stock Titan

Apr 03, 2026
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Apr 03, 2026

Vertex Pharmaceuticals Inc. (NASDAQ:VRTX) Presents a Compelling Growth and Technical Setup - ChartMill

Apr 03, 2026
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Apr 03, 2026

Aberdeen Group plc Has $118.81 Million Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 03, 2026
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Apr 03, 2026

Vertex Pharmaceuticals Incorporated (VRTX) Stock Price, News, Quote & History - Yahoo! Finance Canada

Apr 03, 2026
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Apr 02, 2026

Vertex Pharmaceuticals (VRTX) Stock Drops Despite Market Gains: Important Facts to Note - Yahoo Finance

Apr 02, 2026
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Apr 02, 2026

[ARS] VERTEX PHARMACEUTICALS INC / MA SEC Filing - stocktitan.net

Apr 02, 2026
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Apr 02, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors despite losses on the day - MarketWatch

Apr 02, 2026
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Apr 02, 2026

Vertex (NASDAQ: VRTX) posts $12B 2025 revenue and sets 2026 proxy votes - stocktitan.net

Apr 02, 2026
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Apr 02, 2026

Vertex Pharmaceuticals: Label Expansions For ALYFTREK & TRIKAFTA Plus Strong Demand (VRTX) - Seeking Alpha

Apr 02, 2026
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Apr 02, 2026

The Opioid Crisis Was an Innovation Failure. Vertex Just Showed a Way to Fix It - inc.com

Apr 02, 2026
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Apr 02, 2026

F&V Capital Management LLC Buys Shares of 3,645 Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 02, 2026
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Apr 02, 2026

Allspring Global Investments Holdings LLC Cuts Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Apr 02, 2026
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Apr 02, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Bought by Banque Pictet & Cie SA - MarketBeat

Apr 02, 2026
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Apr 01, 2026

Vertex Advances FDA Filing for IgA Nephropathy Therapy - The Globe and Mail

Apr 01, 2026
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Apr 01, 2026

Vertex Pharmaceuticals (VRTX) Submits Biologics Licensing Application for Accelerated FDA Approval - GuruFocus

Apr 01, 2026
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Apr 01, 2026

Vertex Expands Cystic Fibrosis Reach As Kidney Drug Nears FDA Decision - Yahoo Finance

Apr 01, 2026
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Apr 01, 2026

Vertex Pharmaceuticals (NASDAQ: VRTX) reports 978-share Rule 144 resale and insider sales - Stock Titan

Apr 01, 2026
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Apr 01, 2026

FDA Expands Vertex (VRTX) Drugs' Usage for Cystic Fibrosis - GuruFocus

Apr 01, 2026
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Apr 01, 2026

Vertex Pharmaceuticals Incorporated Announces U.S. FDA Approval of Expanded Use of ALYFTREK (Vanzacaftor/Tezacaftor/Ivacaftor) - MarketScreener

Apr 01, 2026
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Apr 01, 2026

Vertex Pharmaceuticals IncFDA expands indication for trikafta in cf patients ages 2 and older - MarketScreener

Apr 01, 2026
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Apr 01, 2026

Vertex wins FDA label expansion for cystic fibrosis drugs - Seeking Alpha

Apr 01, 2026
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Apr 01, 2026

, Expanding Availability of These Medicines to ~95% of All People With CF in the United States - Business Wire

Apr 01, 2026
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Apr 01, 2026

Vertex Pharmaceuticals (VRTX): Company Profile, Stock Price, News, Rankings - Fortune

Apr 01, 2026
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Mar 31, 2026

Vertex Pharmaceuticals Experiences Evaluation Revision Amid Mixed Performance Indicators - Markets Mojo

Mar 31, 2026
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Mar 31, 2026

Insider Sell: Carmen Bozic Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Mar 31, 2026
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Mar 31, 2026

Vertex (VRTX) CMO sells 2,329 shares in pre-set 10b5-1 trade - Stock Titan

Mar 31, 2026
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Mar 31, 2026

Vertex Pharmaceuticals Incorporated Completes Submission of Biologics Licensing Application for Povetacicept to the U.S. Food and Drug Administration - MarketScreener

Mar 31, 2026
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Mar 31, 2026

[8-K] VERTEX PHARMACEUTICALS INC / MA Reports Material Event - Stock Titan

Mar 31, 2026
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Mar 31, 2026

Promising Biotech Stocks To Watch NowMarch 31st - marketbeat.com

Mar 31, 2026
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Mar 31, 2026

Fierce Biotech Layoff Tracker 2026: Takeda plots 634 US job cuts - Fierce Biotech

Mar 31, 2026
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Mar 31, 2026

Boston Common Asset Management LLC Sells 20,952 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 31, 2026
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Mar 30, 2026

Assessing Vertex Pharmaceuticals (VRTX) Valuation After Recent Share Price Weakness - simplywall.st

Mar 30, 2026
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Mar 30, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Mar 30, 2026
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Mar 30, 2026

VRTX SEC FilingsVertex Pharmaceuticals Inc 10-K, 10-Q, 8-K Forms - Stock Titan

Mar 30, 2026
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Mar 30, 2026

Vertex’s VX-407 Contraceptive Interaction Study Reaches Completion: What Investors Should Watch - TipRanks

Mar 30, 2026
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Mar 30, 2026

BMO reiterates Vertex stock Outperform on cystic fibrosis strength By Investing.com - Investing.com UK

Mar 30, 2026
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Mar 29, 2026

Best Biotech Stocks To Watch TodayMarch 29th - MarketBeat

Mar 29, 2026
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Mar 28, 2026

Vertex Pharmaceuticals Stock Falls 4.6% After FDA Label Warning Hits Alyftrek, Trikafta - TechStock²

Mar 28, 2026
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Mar 28, 2026

Vertex Pharmaceuticals Inc (NASDAQ:VRTX) Emerges as a Prime GARP Investment - ChartMill

Mar 28, 2026
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Mar 28, 2026

Wells Fargo Raises Vertex Pharmaceuticals (VRTX) Price Target to $550 - Insider Monkey

Mar 28, 2026
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Mar 27, 2026

Vertex Pharmaceuticals Inc. stock underperforms Friday when compared to competitors - MarketWatch

Mar 27, 2026
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Mar 27, 2026

Vanguard (VRTX) parent reports 0 shares; subsidiaries to report holdings separately - Stock Titan

Mar 27, 2026
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Mar 27, 2026

Vertex Pharmaceuticals Tumbles Over 3.4% – What’s Behind the Sudden Drop? - Bitget

Mar 27, 2026
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Mar 27, 2026

Vertex’s VX-407 Kidney Study Completion: What Phase 1 Progress Means For VRTX Investors - TipRanks

Mar 27, 2026
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Mar 27, 2026

Carmen Bozic files Form 144; VRTX (NASDAQ: VRTX) insider sales listed - Stock Titan

Mar 27, 2026
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Mar 27, 2026

Analysts Offer Insights on Healthcare Companies: Fractyl Health, Inc. (GUTS), Merck & Company (MRK) and Abbott Laboratories (ABT) - The Globe and Mail

Mar 27, 2026
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Mar 27, 2026

Analysts Offer Insights on Healthcare Companies: Neurogene (NGNE), Vertex Pharmaceuticals (VRTX) and Sarepta Therapeutics (SRPT) - The Globe and Mail

Mar 27, 2026
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Mar 27, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Sold by Congress Asset Management Co. - MarketBeat

Mar 27, 2026
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Mar 27, 2026

Baker Chad R Sells 8,990 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Mar 27, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$761.85
price down icon 1.98%
$746.42
price up icon 0.44%
$318.85
price down icon 3.01%
$162.43
price down icon 1.47%
ONC ONC
$310.79
price up icon 0.76%
Cap:     |  Volume (24h):