463.13
price up icon6.92%   29.98
after-market After Hours: 462.45 -0.68 -0.15%
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Vertex Pharmaceuticals Inc stock is traded at $463.13, with a volume of 2.52M. It is up +6.92% in the last 24 hours and up +8.72% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$433.15
Open:
$440.31
24h Volume:
2.52M
Relative Volume:
1.69
Market Cap:
$117.50B
Revenue:
$11.74B
Net Income/Loss:
$3.68B
P/E Ratio:
32.64
EPS:
14.1888
Net Cash Flow:
$3.34B
1W Performance:
+7.16%
1M Performance:
+8.72%
6M Performance:
+3.73%
1Y Performance:
+1.35%
1-Day Range:
Value
$439.35
$463.85
1-Week Range:
Value
$423.45
$463.85
52-Week Range:
Value
$362.50
$519.68

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,100
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2025-02-10
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
463.13 109.90B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
723.67 77.98B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
473.29 61.42B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
921.80 56.36B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
206.78 44.06B 447.02M -1.18B -906.14M -6.1812

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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04:42 AM

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MSN

04:42 AM
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03:01 AM

Check Out What Whales Are Doing With VRTX - Benzinga

03:01 AM
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03:00 AM

Vertex Pharmaceuticals (VRTX) Upgraded by Morgan Stanley with Op - GuruFocus

03:00 AM
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02:26 AM

Why Vertex Pharmaceuticals (VRTX) Stock Is Up Today - Finviz

02:26 AM
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01:47 AM

Vertex upgraded at Morgan Stanley on kidney pipeline - Seeking Alpha

01:47 AM
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01:00 AM

Sickle Cell Disease Market is Predicted to Exhibit Remarkable Growth at a CAGR of 22.1% During the Forecast Period (2025–2034) Across 6MM, Owing to the Increasing Prevalence, Awareness, and Advancements in Gene Therapies | DelveInsight - GlobeNewswire Inc.

01:00 AM
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11:35 AM

Vertex Wins Wall Street Back With Kidney Drug Bets - Finimize

11:35 AM
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11:30 AM

Why Is Vertex (VRTX) Up 2.7% Since Last Earnings Report? - Yahoo Finance

11:30 AM
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11:29 AM

Vertex Pharmaceuticals (VRTX) Receives Rating Upgrade from Morgan Stanley | VRTX Stock News - GuruFocus

11:29 AM
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10:46 AM

Vertex Up 9.2% in 3 Months: Should You Buy, Sell or Hold the Stock? - Finviz

10:46 AM
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10:37 AM

Transcript : Vertex Pharmaceuticals Incorporated Presents at Citi Annual Global Healthcare Conference 2025, Dec-03-2025 09 - MarketScreener

10:37 AM
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06:28 AM

Is Vertex Pharmaceuticals Incorporated (VX1) stock a buy on weaknessQuarterly Market Summary & Stepwise Swing Trade Plans - Newser

06:28 AM
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06:17 AM

Is Vertex Pharmaceuticals Incorporated stock resilient to inflationJuly 2025 Fed Impact & Consistent Profit Alerts - Newser

06:17 AM
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05:22 AM

Morgan Stanley Upgrades Vertex Pharmaceuticals to Overweight From Equalweight, Adjusts PT to $516 From $438 - MarketScreener

05:22 AM
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05:11 AM

Morgan Stanley upgrades Vertex stock to Overweight on kidney pipeline potential - Investing.com India

05:11 AM
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12:32 PM

Published on: 2025-12-02 23:32:41 - Newser

12:32 PM
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Dec 02, 2025

Akeso’s Goals Beyond Ivonescimab: ‘We Can Hit Vertex And Regeneron-Level Innovation’ - Citeline News & Insights

Dec 02, 2025
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Dec 02, 2025

Why Vertex Pharmaceuticals Incorporated stock appeals to dividend seekersJuly 2025 Catalysts & Fast Exit Strategy with Risk Control - Newser

Dec 02, 2025
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Dec 02, 2025

Can Vertex Pharmaceuticals Incorporated (VX1) stock sustain breakout momentum2025 Technical Overview & High Accuracy Swing Entry Alerts - Newser

Dec 02, 2025
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Dec 02, 2025

Why Vertex Pharmaceuticals Incorporated (VX1) stock stays resilientTrade Analysis Summary & Daily Oversold Stock Bounce Ideas - Newser

Dec 02, 2025
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Dec 01, 2025

Here is What to Know Beyond Why Vertex Pharmaceuticals Incorporated (VRTX) is a Trending Stock - sharewise.com

Dec 01, 2025
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Nov 30, 2025

Is Vertex Pharmaceuticals Incorporated stock ready for breakoutEarnings Growth Report & Low Risk High Reward Ideas - moha.gov.vn

Nov 30, 2025
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Nov 30, 2025

Is Vertex Pharmaceuticals Stock Underperforming the Nasdaq? - MSN

Nov 30, 2025
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Nov 27, 2025

Kidney Disease Trial Success Might Change The Case For Investing In Vertex Pharmaceuticals (VRTX) - Yahoo Finance

Nov 27, 2025
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Nov 27, 2025

How analysts rate Vertex Pharmaceuticals Incorporated stock today2025 Key Highlights & Scalable Portfolio Growth Methods - BỘ NỘI VỤ

Nov 27, 2025
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Nov 27, 2025

Is Vertex Still a Bargain After Latest Pipeline Progress and Five Year 90.6% Gain? - Yahoo Finance

Nov 27, 2025
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Nov 27, 2025

Where Will Vertex Pharmaceuticals Be in 5 Years - sharewise.com

Nov 27, 2025
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Nov 27, 2025

Vertex Pharmaceuticals names Wafi Alshehri as HRBP Director for KSA and the GCC - Indiatimes

Nov 27, 2025
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Nov 26, 2025

What Do Analysts Think About Vertex Pharmaceuticals (VRTX)? - Finviz

Nov 26, 2025
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Nov 26, 2025

Interest rate-sensitive biotech companies are bullish on the New York Stock Exchange. Hedge funds ha.. - 매일경제

Nov 26, 2025
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Nov 26, 2025

Scotiabank Sticks to Their Buy Rating for Vertex Pharmaceuticals (VRTX) - The Globe and Mail

Nov 26, 2025
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Nov 25, 2025

Vertex Pharmaceuticals (VRTX) Leads Hedge Fund Interest in Q3 20 - GuruFocus

Nov 25, 2025
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Nov 23, 2025

2 Healthcare Stocks For Beginner Investors With a 30-Year Time Horizon - Finviz

Nov 23, 2025
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Nov 21, 2025

Vertex Pharmaceuticals (VRTX) Stock Trades Up, Here Is Why - Finviz

Nov 21, 2025
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Nov 21, 2025

Vertex Pharmaceuticals Inc. stock underperforms Friday when compared to competitors despite daily gains - MarketWatch

Nov 21, 2025
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Nov 21, 2025

Is Vertex Pharmaceuticals Incorporated a good long term investmentVolatility Index Analysis & Big Returns Low Cost - earlytimes.in

Nov 21, 2025
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Nov 21, 2025

Vertex Pharmaceuticals Stock: Analyst Estimates & Ratings - MSN

Nov 21, 2025
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Nov 20, 2025

[Form 4] VERTEX PHARMACEUTICALS INC / MA Insider Trading Activity - Stock Titan

Nov 20, 2025
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Nov 20, 2025

Shareholder Carney Lloyd Foundation Files To Sell 800 Of Vertex Pharmaceuticals Inc [VRTX] - TradingView

Nov 20, 2025
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Nov 20, 2025

2 Inflation-Proof Growth Stocks That Could Outperform the Market - Finviz

Nov 20, 2025
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Nov 20, 2025

Vertex Nears Historic Breakthrough: Stem Cell Therapy Poised to Transform Type 1 Diabetes Treatment - Azat TV

Nov 20, 2025
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Nov 20, 2025

Vertex Pharmaceuticals Incorporated (0QZU.IL) stock price, news, quote and history - Yahoo Finance UK

Nov 20, 2025
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Nov 20, 2025

How risky is Vertex Pharmaceuticals Incorporated (VX1) stock compared to peers2025 Technical Overview & Free Weekly Watchlist of Top Performers - newser.com

Nov 20, 2025
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Nov 20, 2025

How Vertex Pharmaceuticals Incorporated (VX1) stock moves on employment dataGold Moves & Weekly Chart Analysis and Guides - newser.com

Nov 20, 2025
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Nov 19, 2025

Insider Sell: Atkinson Edward Morrow III Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Nov 19, 2025
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Nov 19, 2025

Vertex, Crispr’s Casgevy Accused of Infringing New ToolGen Patent - Bloomberg Law News

Nov 19, 2025
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Nov 19, 2025

Vertex Pharmaceuticals Inc. Stock Underperforms Wednesday When Compared To Competitors - 富途牛牛

Nov 19, 2025
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Nov 19, 2025

Vertex Pharmaceuticals Inc. Stock Falls 3.3%, Underperforms Peers - 富途牛牛

Nov 19, 2025
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Nov 19, 2025

VP Atkinson III Sells 2,500 ($1.1M) Of Vertex Pharmaceuticals Inc [VRTX] - TradingView

Nov 19, 2025

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$723.67
price down icon 2.47%
$473.29
price up icon 1.80%
$921.80
price up icon 0.70%
$206.78
price up icon 0.09%
biotechnology ONC
$337.86
price up icon 2.32%
Cap:     |  Volume (24h):