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Vertex Pharmaceuticals Inc stock is traded at $473.13, with a volume of 396.30K. It is up +0.66% in the last 24 hours and up +4.62% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$469.90
Open:
$466.79
24h Volume:
396.30K
Relative Volume:
0.28
Market Cap:
$120.01B
Revenue:
$11.74B
Net Income/Loss:
$3.68B
P/E Ratio:
33.35
EPS:
14.1888
Net Cash Flow:
$3.34B
1W Performance:
-0.80%
1M Performance:
+4.62%
6M Performance:
+2.36%
1Y Performance:
+2.46%
1-Day Range:
Value
$464.01
$473.74
1-Week Range:
Value
$464.01
$485.00
52-Week Range:
Value
$362.50
$519.68

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,100
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2025-02-10
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
473.00 119.22B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
752.29 77.93B 14.34B 4.50B 3.88B 41.57
Biotechnology icon
ARGX
Argen X Se Adr
839.30 52.01B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
338.66 44.66B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ONC
Beone Medicines Ltd Adr
342.30 37.67B 4.98B 69.60M 525.67M 0.5198

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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04:22 AM

Principal Financial Group Inc. Reduces Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

04:22 AM
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Feb 01, 2026

Atle Fund Management AB Reduces Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 01, 2026
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Feb 01, 2026

Vertex Pharmaceuticals Incorporated $VRTX Holdings Lifted by National Pension Service - MarketBeat

Feb 01, 2026
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Feb 01, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Sold by TD Waterhouse Canada Inc. - MarketBeat

Feb 01, 2026
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Feb 01, 2026

Vertex Pain Setback Prompts Fund Exit And Recheck Of Valuation Gap - Yahoo Finance

Feb 01, 2026
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Jan 31, 2026

Why Analysts Are Positive on Vertex Pharmaceuticals Incorporated (VRTX)'s Story - Finviz

Jan 31, 2026
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Jan 31, 2026

Biotech Stocks To Keep An Eye OnJanuary 31st - MarketBeat

Jan 31, 2026
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Jan 31, 2026

Why Analysts Are Positive on Vertex Pharmaceuticals Incorporated (VRTX)’s Story - Insider Monkey

Jan 31, 2026
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Jan 31, 2026

Welch & Forbes LLC Buys 3,102 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 31, 2026
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Jan 31, 2026

AustralianSuper Pty Ltd Trims Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 31, 2026
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Jan 30, 2026

Why Vertex Pharmaceuticals (VRTX) Dipped More Than Broader Market Today - Yahoo Finance

Jan 30, 2026
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Jan 30, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Sold by Fidelis Capital Partners LLC - MarketBeat

Jan 30, 2026
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Jan 29, 2026

Prediction: 2026 Will Be the Year of Vertex Pharmaceuticals - The Globe and Mail

Jan 29, 2026
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Jan 29, 2026

Best Biotech Stocks To Watch NowJanuary 29th - MarketBeat

Jan 29, 2026
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Jan 29, 2026

What's Driving the Market Sentiment Around Vertex Pharmaceuticals Inc? - Benzinga

Jan 29, 2026
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Jan 29, 2026

Assessing Vertex Pharmaceuticals (VRTX) Valuation After Fund Exit And Setback For Journavx Pain Label - simplywall.st

Jan 29, 2026
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Jan 29, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Acquired by Strategic Advisors LLC - MarketBeat

Jan 29, 2026
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Jan 29, 2026

Vertex Pharmaceuticals Inc. (NASDAQ:VRTX) Presents a Compelling Value Case - Chartmill

Jan 29, 2026
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Jan 29, 2026

New York State Common Retirement Fund Cuts Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 29, 2026
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Jan 29, 2026

Mirae Asset Global Investments Co. Ltd. Buys 6,468 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 29, 2026
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Jan 29, 2026

Truist Financial Corp Sells 66,225 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 29, 2026
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Jan 28, 2026

Vertex Pharma upgraded at RBC Capital Markets citing upside in 2026 - MSN

Jan 28, 2026
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Jan 28, 2026

Barclays Upgrades Vertex Pharmaceuticals (VRTX) - Nasdaq

Jan 28, 2026
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Jan 28, 2026

Promising Biotech Stocks To ResearchJanuary 28th - MarketBeat

Jan 28, 2026
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Jan 28, 2026

Barclays Upgrades Vertex Pharmaceuticals (VRTX) with Increased P - GuruFocus

Jan 28, 2026
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Jan 28, 2026

Bank of America Securities Keeps Their Buy Rating on Vertex Pharmaceuticals (VRTX) - The Globe and Mail

Jan 28, 2026
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Jan 28, 2026

Little House Capital LLC Increases Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 28, 2026
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Jan 28, 2026

Stonegate Investment Group LLC Has $769,000 Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 28, 2026
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Jan 28, 2026

Here’s Why Hardman Johnston Global Equity Strategy Sold Vertex Pharmaceuticals (VRTX) - Yahoo Finance

Jan 28, 2026
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Jan 28, 2026

Vertex Pharmaceuticals (VRTX) Receives a Buy from Citi - The Globe and Mail

Jan 28, 2026
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Jan 28, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Sold by EFG Asset Management North America Corp. - MarketBeat

Jan 28, 2026
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Jan 27, 2026

Autologous Cell Therapy Market Size to Reach US$ 44.55 Billion by 2033 | Astute Analytica - GlobeNewswire Inc.

Jan 27, 2026
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Jan 27, 2026

Promising Biotech Stocks To Follow NowJanuary 27th - MarketBeat

Jan 27, 2026
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Jan 27, 2026

Barlow Wealth Partners Inc. Sells 21,078 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 27, 2026
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Jan 26, 2026

Physician Views Results: Vertex's Journavx impresses in acute pain, as case for chronic comes into focus - FirstWord Pharma

Jan 26, 2026
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Jan 26, 2026

VRTX Stock Surges 6.1% With A 5-day Winning Spree On Analyst Upgrades - Trefis

Jan 26, 2026
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Jan 26, 2026

TIME100 Most Influential Companies 2025: Vertex Pharmaceuticals - Time Magazine

Jan 26, 2026
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Jan 26, 2026

Vertex Pharmaceuticals (VRTX) Stock Analysis: A Biotech Leader With 8% Potential Upside - DirectorsTalk Interviews

Jan 26, 2026
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Jan 26, 2026

Vertex Pharmaceuticals (VRTX) Sees Price Target Increase by UBS to $545 | VRTX Stock News - GuruFocus

Jan 26, 2026
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Jan 26, 2026

Best Biotech Stocks To Follow NowJanuary 26th - MarketBeat

Jan 26, 2026
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Jan 26, 2026

Vertex Pharmaceuticals price target raised to $545 from $535 at UBS - TipRanks

Jan 26, 2026
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Jan 26, 2026

Lbp Am Sa Grows Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 26, 2026
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Jan 25, 2026

UniSuper Management Pty Ltd Has $8.03 Million Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 25, 2026
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Jan 25, 2026

Baillie Gifford & Co. Sells 5,423 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 25, 2026
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Jan 25, 2026

AMF Tjanstepension AB Reduces Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 25, 2026
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Jan 24, 2026

A Look At Vertex Pharmaceuticals (VRTX) Valuation After Recent Analyst Upgrades And CASGEVY Approval - Yahoo Finance

Jan 24, 2026
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Jan 24, 2026

Y Intercept Hong Kong Ltd Takes $10.88 Million Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 24, 2026
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Jan 24, 2026

How Evolving Analyst Assumptions Are Reshaping The Story For Vertex Pharmaceuticals (VRTX) - Yahoo Finance

Jan 24, 2026
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Jan 24, 2026

Resona Asset Management Co. Ltd. Sells 4,351 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 24, 2026
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Jan 24, 2026

Jennison Associates LLC Decreases Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 24, 2026
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Jan 24, 2026

Strs Ohio Has $31.58 Million Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jan 24, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Vertex Pharmaceuticals Inc Stock (VRTX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
WAGNER CHARLES F JR
EVP, CO & FO
Jan 06 '26
Option Exercise
189.38
9,532
1,805,170
47,257
WAGNER CHARLES F JR
EVP, CO & FO
Jan 06 '26
Sale
461.00
9,532
4,394,252
37,725
$754.12
price up icon 1.74%
$845.34
price up icon 0.46%
$338.58
price up icon 0.14%
biotechnology ONC
$342.60
price up icon 0.56%
$154.24
price down icon 1.92%
Cap:     |  Volume (24h):