476.90
price up icon1.63%   7.63
after-market After Hours: 475.00 -1.90 -0.40%
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Vertex Pharmaceuticals Inc stock is traded at $476.90, with a volume of 1.01M. It is up +1.63% in the last 24 hours and up +7.88% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$469.27
Open:
$466.94
24h Volume:
1.01M
Relative Volume:
0.70
Market Cap:
$121.15B
Revenue:
$12.07B
Net Income/Loss:
$3.95B
P/E Ratio:
31.10
EPS:
15.3349
Net Cash Flow:
$3.19B
1W Performance:
-2.96%
1M Performance:
+7.88%
6M Performance:
+20.93%
1Y Performance:
-0.71%
1-Day Range:
Value
$465.00
$479.12
1-Week Range:
Value
$463.00
$494.05
52-Week Range:
Value
$362.50
$519.68

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,100
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-02-12
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
476.90 119.21B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
779.67 82.71B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
844.41 52.43B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
336.19 45.01B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
362.14 39.23B 4.98B 69.60M 525.67M 0.5198

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

pulisher
06:50 AM

Could Vertex Stock Help Turn $100,000 Into $1 Million by 2036? - Nasdaq

06:50 AM
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Feb 21, 2026

Tredje AP fonden Sells 65,290 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 21, 2026
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Feb 21, 2026

Mitsubishi UFJ Asset Management UK Ltd. Takes Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 21, 2026
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Feb 21, 2026

Jupiter Asset Management Ltd. Invests $25.70 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 21, 2026
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Feb 20, 2026

CRISPR Therapeutics Gains After Earnings as Pipeline Hope Grows - Investing.com

Feb 20, 2026
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Feb 20, 2026

HighTower Advisors LLC Sells 12,332 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 20, 2026
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Feb 20, 2026

Vertex: The Quiet Biotech Compounder I'd Happily Hold Through Any Market Crash - AOL.com

Feb 20, 2026
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Feb 19, 2026

Is Vertex Pharmaceuticals (VRTX) Now Offering A Compelling Entry Point After Flat One Year Returns - Yahoo Finance

Feb 19, 2026
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Feb 19, 2026

Insider Sell: Atkinson Edward Morrow III Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Feb 19, 2026
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Feb 19, 2026

Vertex Broadens Beyond Cystic Fibrosis As CASGEVY And Pipeline Take Shape - Yahoo Finance

Feb 19, 2026
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Feb 19, 2026

Madrigal Pharmaceuticals, Inc. reports strong Rezdiffra sales growth in Q4 2025; first full year of launch approaches $1 billion in net sales - AlphaStreet News

Feb 19, 2026
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Feb 19, 2026

Mcrae Capital Management Inc. Boosts Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 19, 2026
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Feb 19, 2026

Cumberland Partners Ltd Has $3.82 Million Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 19, 2026
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Feb 19, 2026

Vertex Q4 2025 Earnings: Revenue Beats, Driven by CF Growth & New LaunchesNews and Statistics - IndexBox

Feb 19, 2026
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Feb 19, 2026

5 Insightful Analyst Questions From Vertex Pharmaceuticals's Q4 Earnings Call - Finviz

Feb 19, 2026
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Feb 19, 2026

5 Insightful Analyst Questions From Vertex Pharmaceuticals’s Q4 Earnings Call - TradingView

Feb 19, 2026
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Feb 18, 2026

Insider Selling: Vertex Pharmaceuticals (NASDAQ:VRTX) EVP Sells 1,500 Shares of Stock - MarketBeat

Feb 18, 2026
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Feb 18, 2026

Vertex Pharmaceuticals Stock: Is The Bull Run Over (Rating Downgrade) (NASDAQ:VRTX) - Seeking Alpha

Feb 18, 2026
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Feb 18, 2026

Vertex Pharmaceuticals (VRTX) Analyst Rating Update: Canaccord G - GuruFocus

Feb 18, 2026
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Feb 18, 2026

Grange Capital LLC Makes New Investment in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 18, 2026
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Feb 18, 2026

PNC Financial Services Group Inc. Has $27.33 Million Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 18, 2026
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Feb 18, 2026

Vertex Pharmaceuticals stock: Is Wall Street bullish or bearish? - MSN

Feb 18, 2026
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Feb 17, 2026

Vertex to Participate in TD Cowen 46th Annual Health Care Conference on March 3 - PharmiWeb.com

Feb 17, 2026
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Feb 17, 2026

Vertex Pharmaceuticals Topples 10% On A Series Of First-Quarter Setbacks - MSN

Feb 17, 2026
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Feb 17, 2026

Narrow-Moat Vertex's Strong CF Sales Drive Growth as Non-CF Portfolio Starts to Gain Traction - Morningstar

Feb 17, 2026
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Feb 17, 2026

Vertex CEO to discuss strategy at TD Cowen health care conference - Stock Titan

Feb 17, 2026
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Feb 17, 2026

Vertex Pharmaceuticals (VRTX) Sees Analyst Rating Maintained wit - GuruFocus

Feb 17, 2026
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Feb 17, 2026

Here is What to Know Beyond Why Vertex Pharmaceuticals Incorporated (VRTX) is a Trending Stock - Yahoo Finance

Feb 17, 2026
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Feb 17, 2026

HC Wainwright & Co. Raises Vertex Pharmaceuticals (VRTX) Price Target | VRTX Stock News - GuruFocus

Feb 17, 2026
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Feb 17, 2026

Vanguard Group Inc. Boosts Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 17, 2026
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Feb 17, 2026

NEOS Investment Management LLC Purchases 37,296 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 17, 2026
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Feb 17, 2026

Skandinaviska Enskilda Banken AB publ Has $60.39 Million Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 17, 2026
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Feb 17, 2026

Public Sector Pension Investment Board Has $8.78 Million Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 17, 2026
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Feb 17, 2026

Top-Rated Stocks: Vertex Pharmaceuticals Sees Composite Rating Climb To 96 - Investor's Business Daily

Feb 17, 2026
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Feb 17, 2026

Vertex Pharmaceuticals Stock: Is Wall Street Bullish or Bearish? - Barchart.com

Feb 17, 2026
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Feb 16, 2026

Oppenheimer Upgrades Vertex Pharmaceuticals (VRTX) - Nasdaq

Feb 16, 2026
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Feb 16, 2026

Zions Bancorporation National Association UT Buys 9,452 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 16, 2026
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Feb 16, 2026

Vertex Pharmaceuticals Incorporated $VRTX Stake Increased by State of New Jersey Common Pension Fund D - MarketBeat

Feb 16, 2026
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Feb 16, 2026

Cibc World Market Inc. Cuts Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 16, 2026
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Feb 16, 2026

Vertex Pharmaceuticals (VRTX) Stock Analysis: A Biotech Powerhouse with 6.93% Upside Potential - DirectorsTalk Interviews

Feb 16, 2026
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Feb 15, 2026

Vertex’s Journavx Surpasses Half a Million Prescriptions Amid Biopharma Sector Developments - geneonline.com

Feb 15, 2026
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Feb 15, 2026

1 reason I'd buy Vertex Pharmaceuticals stock and never sell - MSN

Feb 15, 2026
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Feb 15, 2026

Promising Biotech Stocks To Add to Your WatchlistFebruary 15th - MarketBeat

Feb 15, 2026
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Feb 15, 2026

Shell Asset Management Co. Sells 10,515 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 15, 2026
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Feb 15, 2026

Prospera Financial Services Inc Reduces Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 15, 2026
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Feb 15, 2026

Vertex Pharmaceuticals Incorporated $VRTX Shares Purchased by Aberdeen Group plc - MarketBeat

Feb 15, 2026
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Feb 15, 2026

ABN Amro Investment Solutions Has $49.33 Million Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 15, 2026
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Feb 15, 2026

Vertex Autoimmune Deal With WuXi Adds New Angle To VRTX Valuation Story - Yahoo! Finance Canada

Feb 15, 2026
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Feb 14, 2026

Assetmark Inc. Decreases Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Feb 14, 2026
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Feb 14, 2026

Decoding Vertex Pharmaceuticals Inc (VRTX): A Strategic SWOT Ins - GuruFocus

Feb 14, 2026
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Feb 13, 2026

Vertex Pharmaceuticals (VRTX) Receives Boosted Price Target from HC Wainwright & Co. | VRTX Stock News - GuruFocus

Feb 13, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$779.67
price down icon 0.35%
$844.41
price down icon 0.34%
$336.19
price down icon 0.94%
biotechnology ONC
$362.14
price up icon 2.16%
$164.91
price up icon 2.43%
Cap:     |  Volume (24h):