515.44
price up icon0.17%   0.88
after-market After Hours: 514.51 -0.93 -0.18%
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Vertex Pharmaceuticals Inc stock is traded at $515.44, with a volume of 852.62K. It is up +0.17% in the last 24 hours and down -2.68% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$514.56
Open:
$522.1
24h Volume:
852.62K
Relative Volume:
0.59
Market Cap:
$130.64B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
30.56
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
-5.62%
1M Performance:
-2.68%
6M Performance:
+4.68%
1Y Performance:
+29.71%
1-Day Range:
Value
$511.81
$522.10
1-Week Range:
Value
$511.81
$535.00
52-Week Range:
Value
$374.17
$560.25

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-11-02
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, MRNA, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
515.44 130.42B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
781.49 81.67B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
984.39 61.56B 4.16B 1.29B 734.26M 19.58
MRNA icon
MRNA
Moderna Inc
143.97 54.54B 2.23B -3.19B -1.60B -8.1462
RVMD icon
RVMD
Revolution Medicines Inc
203.77 43.59B 742.00K -1.37B -1.07B -7.0731

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

pulisher
Sep 11, 2026

Vertex Pharmaceuticals Incorporated (VRTX): Crinetics Acquisition Creates a New Growth Engine Beyond Cystic Fibrosis - finance.yahoo.com

Sep 11, 2026
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Sep 11, 2026

Amgen vs. CRISPR Therapeutics: Which Healthcare Stock Is a Better Buy in 2026? - The Motley Fool

Sep 11, 2026
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Sep 11, 2026

Vertex Pharma stock gains analyst support as JPMorgan raises price target - ad-hoc-news.de

Sep 11, 2026
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Sep 11, 2026

VRTX Reinstated by JP Morgan -- Price Target Raised to $560 - GuruFocus

Sep 11, 2026
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Sep 11, 2026

Vertex trades higher after JPM gives bullish rating - TradingView

Sep 11, 2026
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Sep 11, 2026

Strong Core Business, Raised Guidance Push Vertex Pharmaceuticals Higher - FXEmpire

Sep 11, 2026
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Sep 11, 2026

Executives On The Move: Vertex Expands Its Leadership Team Following Crinetics Acquisition - insights.citeline.com

Sep 11, 2026
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Sep 11, 2026

Vertex Pharma stock heads into the open after a modest gain - ad-hoc-news.de

Sep 11, 2026
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Sep 10, 2026

Vertex Pharma EVP Jasper van Grunsven files initial beneficial ownership statement - Bitget

Sep 10, 2026
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Sep 10, 2026

Vertex Pharmaceuticals (VRTX) Q1 2026 Earnings Call Transcript - Fortune

Sep 10, 2026
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Sep 10, 2026

Q2 Rundown: Vertex Pharmaceuticals (NASDAQ:VRTX) Vs Other Therapeutics Stocks - finance.yahoo.com

Sep 10, 2026
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Sep 10, 2026

Vertex Pharmaceuticals (VRTX) executive gets 8,682-share stock grant - Stock Titan

Sep 10, 2026
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Sep 10, 2026

Vertex (NASDAQ: VRTX) executive listed as insider with no reported shares - Stock Titan

Sep 10, 2026
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Sep 10, 2026

Frazier Life Sciences nets $1.1B in long-running fund aimed at small, midsize biotechs - Fierce Biotech

Sep 10, 2026
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Sep 10, 2026

Vertex Pharma stock edges near 52-week high as pipeline expansion supports valuation - ad-hoc-news.de

Sep 10, 2026
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Sep 09, 2026

Vertex at Wells Fargo healthcare conference: renal pipeline takes center stage - Investing.com

Sep 09, 2026
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Sep 09, 2026

Vertex Pharmaceuticals Inc. stock underperforms Wednesday when compared to competitors - MarketWatch

Sep 09, 2026
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Sep 09, 2026

Vertex Pharma stock falls as market digests Crinetics deal and valuation risks - ad-hoc-news.de

Sep 09, 2026
pulisher
Sep 09, 2026

Anti-kickback law at play, court tells Vertex as it schools HHS - BioWorld News

Sep 09, 2026
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Sep 09, 2026

Where does Vertex Pharmaceuticals (NASDAQ:VRTX) fit within the Healthcare stocks conversation? - Kalkine Media

Sep 09, 2026
pulisher
Sep 09, 2026

Vertex Pharmaceuticals: Solid Growth But Valuation Still Requires Flawless Execution - Seeking Alpha

Sep 09, 2026
pulisher
Sep 09, 2026

Vertex Pharma stock heads into the open after a 3.1 percent drop - ad-hoc-news.de

Sep 09, 2026
pulisher
Sep 08, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Moved Down by 3.06% on Sep 8: What Signal Does It Send? - TradingKey

Sep 08, 2026
pulisher
Sep 08, 2026

Goldman Sachs Just Added Vertex Pharmaceuticals to Its Conviction List. Here's the Bull Case for the Big Biotech Stock - fool.com

Sep 08, 2026
pulisher
Sep 08, 2026

Vertex Pharmaceuticals (VRTX) Suffers a Larger Drop Than the General Market: Key Insights - finance.yahoo.com

Sep 08, 2026
pulisher
Sep 08, 2026

Vertex Pharmaceuticals Inc. stock underperforms Tuesday when compared to competitors - MarketWatch

Sep 08, 2026
pulisher
Sep 08, 2026

Vertex Pharmaceuticals stock edges lower as market digests strong Q2 figures and insider selling - AD HOC NEWS

Sep 08, 2026
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Sep 08, 2026

Vertex shares fall as investors digest Crinetics acquisition and related financing plans - Quiver Quantitative

Sep 08, 2026
pulisher
Sep 08, 2026

Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know - finance.yahoo.com

Sep 08, 2026
pulisher
Sep 08, 2026

Could Nasdaq Focus Lift Attention on Vertex Pharmaceuticals (NASDAQ:VRTX)? - Kalkine Media

Sep 08, 2026
pulisher
Sep 07, 2026

Vertex Pharmaceuticals stock steadies near a 52-week high - AD HOC NEWS

Sep 07, 2026
pulisher
Sep 07, 2026

David Taylor sold $ VRTX on Aug. 26, 2026 - Quiver Quantitative

Sep 07, 2026
pulisher
Sep 07, 2026

Why Vertex stock is sliding today - Wealth Awesome

Sep 07, 2026
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Sep 07, 2026

Vertex Pharmaceuticals (VRTX) Stock Analysis: A Biotech Titan with 4.29% Upside and Robust Buy Ratings - DirectorsTalk Interviews

Sep 07, 2026
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Sep 06, 2026

Vertex Pharma stock slips as revenue and EPS stay in view - AD HOC NEWS

Sep 06, 2026
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Sep 05, 2026

Vertex makes some big people moves, completes its largest acquisition - The Boston Globe

Sep 05, 2026
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Sep 04, 2026

Vertex Fertility Aid Plan Would Violate Kickback Law - Law360

Sep 04, 2026
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Sep 04, 2026

Vertex Pharmaceuticals Inc. stock underperforms Friday when compared to competitors - MarketWatch

Sep 04, 2026
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Sep 04, 2026

Vertex vs. Regeneron: Which Biotech Giant Is the Better Buy Right Now? - The Motley Fool

Sep 04, 2026
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Sep 04, 2026

Here's How Much $100 Invested In Vertex Pharmaceuticals 20 Years Ago Would Be Worth Today - Benzinga

Sep 04, 2026
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Sep 04, 2026

Chutes & Ladders—Invivyd's chairman adds CEO role ahead of COVID readout - Fierce Biotech

Sep 04, 2026
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Sep 04, 2026

Is Vertex Pharmaceuticals (VRTX) Undervalued Following Casgevy’s FDA Label Expansion? - simplywall.st

Sep 04, 2026
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Sep 03, 2026

Vertex Tops Citi’s Biotech Picks After Crinetics Deal Completion By Investing.com - Investing.com Canada

Sep 03, 2026
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Sep 03, 2026

Fierce Biotech Layoff Tracker 2026: Novartis nixes Swiss site; TScan telegraphs 75% headcount drop - fiercebiotech.com

Sep 03, 2026
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Sep 02, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Sep 02, 2026
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Sep 02, 2026

Vertex stock wins Overweight at Morgan Stanley (VRTX:NASDAQ) - Seeking Alpha

Sep 02, 2026
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Sep 02, 2026

How Is Vertex Pharmaceuticals' Stock Performance Compared to Other Biotech Stocks? - Barchart.com

Sep 02, 2026
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Sep 02, 2026

Why Is Vertex (VRTX) Up 14.4% Since Last Earnings Report? - Yahoo Finance

Sep 02, 2026
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Sep 02, 2026

Vertex Pharmaceuticals stock hits all-time high at $555.84 By Investing.com - Investing.com Canada

Sep 02, 2026
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Sep 02, 2026

Vertex Pharmaceuticals stock hits all-time high at $555.84 - Investing.com India

Sep 02, 2026
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Sep 01, 2026

Vertex (VRTX) Stock Trades At A Premium On Earnings Yet Looks Fair On Broader Checks - Yahoo Finance

Sep 01, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$781.49
price down icon 1.48%
$984.39
price up icon 0.04%
$143.97
price up icon 5.38%
$203.77
price up icon 0.21%
ONC ONC
$346.51
price up icon 1.38%
Cap:     |  Volume (24h):