428.34
price up icon0.76%   3.25
after-market After Hours: 431.00 2.66 +0.62%
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Vertex Pharmaceuticals Inc stock is traded at $428.34, with a volume of 1.57M. It is up +0.76% in the last 24 hours and up +1.04% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$425.09
Open:
$420.63
24h Volume:
1.57M
Relative Volume:
1.22
Market Cap:
$108.72B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
25.39
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
-2.03%
1M Performance:
+1.04%
6M Performance:
-7.51%
1Y Performance:
-4.06%
1-Day Range:
Value
$420.01
$429.01
1-Week Range:
Value
$420.01
$450.00
52-Week Range:
Value
$362.50
$507.92

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-05-04
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
428.34 107.89B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
618.95 63.21B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
813.14 49.89B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
292.58 38.20B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
155.99 32.17B 742.00K -1.37B -1.07B -7.0731

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

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04:06 AM

Vertex (VRTX) legal chief sells 828 shares in pre-set 10b5-1 trade - Stock Titan

04:06 AM
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04:00 AM

Vertex to Participate in the Goldman Sachs 47th Annual Global Healthcare Conference on June 10 - Business Wire

04:00 AM
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12:30 PM

CRISPR Therapeutics Stock Is Absurdly Cheap -- Here's Why Analysts See 437% Upside Potential - The Motley Fool

12:30 PM
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11:30 AM

Vertex (VRTX) Up 0.2% Since Last Earnings Report: Can It Continue? - Yahoo Finance Singapore

11:30 AM
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09:44 AM

Analysts’ Top Healthcare Picks: Vertex Pharmaceuticals (VRTX), Bicara Therapeutics Inc. (BCAX) - The Globe and Mail

09:44 AM
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Jun 02, 2026

Madrigal Pharmaceuticals Stock Could Become The Next Vertex (NASDAQ:MDGL) - Seeking Alpha

Jun 02, 2026
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Jun 02, 2026

Insider Sell: Carmen Bozic Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Jun 02, 2026
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Jun 02, 2026

Vertex Pharmaceuticals Inc stock (US92532F1003): shares slip after insider sales and FDA update on p - AD HOC NEWS

Jun 02, 2026
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Jun 02, 2026

Is Vertex Pharmaceuticals (VRTX) Offering An Opportunity After Recent Share Price Consolidation? - Yahoo Finance

Jun 02, 2026
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Jun 02, 2026

Vertex Pharmaceuticals Inc. stock underperforms Tuesday when compared to competitors - MarketWatch

Jun 02, 2026
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Jun 02, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Closed Down by 3.03% on Jun 2: Facts Behind the Movement - TradingKey

Jun 02, 2026
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Jun 02, 2026

Vertex Pharmaceuticals Insider Sold Shares Worth $888,300, According to a Recent SEC Filing - marketscreener.com

Jun 02, 2026
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Jun 02, 2026

Vertex (VRTX) CMO executes 1,974-share planned sale, retains holdings - Stock Titan

Jun 02, 2026
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Jun 02, 2026

Should FDA’s IgA Nephropathy BLA Acceptance for Povetacicept Reshape Vertex Pharmaceuticals’ (VRTX) Investment Narrative? - Yahoo Finance

Jun 02, 2026
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Jun 02, 2026

FDA Accepts Vertex's BLA for Povetacicept in IgA Nephropathy - Yahoo Finance Singapore

Jun 02, 2026
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Jun 02, 2026

Vertex Pharmaceuticals Inc stock (US92532F1003): insider sales and Q1 2026 figures in focus - AD HOC NEWS

Jun 02, 2026
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Jun 02, 2026

Acute Pain Market Set for Strong Expansion Through 2036 Amid Rising Investment Interest – DelveInsight | Vertex Pharma, Heron Therapeutics, Neumentum, Cali Biosciences - Barchart.com

Jun 02, 2026
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Jun 02, 2026

Vertex Pharma stock (US92532F1003): FDA accepts povetacicept filing as shares trade steady on Nasdaq - AD HOC NEWS

Jun 02, 2026
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Jun 02, 2026

Vertex Pharmaceuticals stock: Is VRTX underperforming the healthcare sector? - MSN

Jun 02, 2026
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Jun 01, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors despite losses on the day - MarketWatch

Jun 01, 2026
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Jun 01, 2026

Vertex Pharmaceuticals (NASDAQ: VRTX) insider Joy Liu reports share sales - Stock Titan

Jun 01, 2026
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Jun 01, 2026

Vertex Pharmaceuticals Stock: Is VRTX Underperforming the Healthcare Sector? - Yahoo Finance

Jun 01, 2026
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Jun 01, 2026

Vertex Pharmaceuticals (VRTX) Receives FDA BLA Acceptance for Po - GuruFocus

Jun 01, 2026
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Jun 01, 2026

Vertex Stock Down Nearly 8% in 3 Months: Time to Buy or Stay Cautious? - Yahoo Finance

Jun 01, 2026
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Jun 01, 2026

Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know - Yahoo Finance Singapore

Jun 01, 2026
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Jun 01, 2026

FDA accepts Vertex filing for IgAN drug povetacicept By Investing.com - Investing.com Canada

Jun 01, 2026
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Jun 01, 2026

Vertex announces US FDA acceptance of biologics license application for accelerated approval of povetacicept in IgA nephropathy - marketscreener.com

Jun 01, 2026
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Jun 01, 2026

Vertex Announces US FDA Acceptance of Biologics License Application for Accelerated Approval of Povetacicept in IgA Nephropathy - Business Wire

Jun 01, 2026
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Jun 01, 2026

VERTEX PHARMACEUTICALS INC (NASDAQ:VRTX): Affordable Growth with Strong Fundamentals - ChartMill

Jun 01, 2026
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May 31, 2026

Vertex Pharmaceuticals (VRTX) Q1 2026 Earnings Call Transcript - Fortune

May 31, 2026
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May 31, 2026

MFS Core Equity Portfolio's Vertex Pharmaceuticals Inc(VRTX) Holding History - GuruFocus

May 31, 2026
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May 30, 2026

Vertex Pharma stock (US92532F1003): Insider sales and Norges Bank stake highlight ownership dynamics - AD HOC NEWS

May 30, 2026
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May 30, 2026

Committee Stocks On The Move: Uber And Vertex Pharma Dybala (RYo07l9B0s) - Mshale

May 30, 2026
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May 30, 2026

Is Vertex Pharmaceuticals Successfully Diversifying Beyond Cystic Fibrosis - Kavout

May 30, 2026
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May 29, 2026

Vertex Pharmaceuticals (VRTX) affiliate reports multiple share sales, proceeds listed - Stock Titan

May 29, 2026
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May 29, 2026

Vertex Pharma stock (US92532F1003): Valuation stays in focus after a fresh move - AD HOC NEWS

May 29, 2026
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May 29, 2026

VRTX: Renal franchise set to rival CF as new therapies and launches drive next phase of growth - TradingView

May 29, 2026
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May 29, 2026

VRTX News | VERTEX PHARMACEUTICALS INC (NASDAQ:VRTX) - ChartMill

May 29, 2026
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May 29, 2026

Vertex (VRTX) Announces Health Canada Acceptance of NDS for Suzetrigine - Insider Monkey

May 29, 2026
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May 28, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

May 28, 2026
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May 28, 2026

Vertex Pharmaceuticals Inc stock (US92532F1003): Texas pension fund disclosure spotlights biotech he - AD HOC NEWS

May 28, 2026
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May 28, 2026

These 2 Cheap Biotech Stocks Offer Potential for Low-Beta Growth - Yahoo Finance

May 28, 2026
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May 28, 2026

Anti-Aging Cell Therapy Reaches Major GMP Milestone as Wave of Clinical Advancements Gain Momentum - PR Newswire

May 28, 2026
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May 28, 2026

Vertex’s Journavx made history, but left a void in the pain space - Pharma Voice

May 28, 2026
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May 27, 2026

Viridian, awaiting FDA decision, taps WuXi Bio in supply deal - Fierce Pharma

May 27, 2026
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May 27, 2026

Truist Financial Upgrades Vertex Pharmaceuticals(VRTX.US) to Buy Rating, Announces Target Price $542 - Moomoo

May 27, 2026
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May 27, 2026

Vertex Pharmaceuticals Incorporated Shs Cert Deposito Arg Repr 0.00990099 Shs - TradingView

May 27, 2026
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May 27, 2026

Ending the Pharma Relay Race with a Non-Opioid Breakthrough - Pharmaceutical Executive

May 27, 2026
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May 27, 2026

Layoff Tracker: J&J trims New Jersey headcount by 56 - BioSpace

May 27, 2026
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May 27, 2026

Truist assumes Vertex stock coverage with buy rating on kidney drugs - Investing.com

May 27, 2026
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May 26, 2026

Vertex Pharma stock (US92532F1003): cystic fibrosis franchise underpins valuation as investors weigh - AD HOC NEWS

May 26, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$618.95
price up icon 2.66%
$813.14
price up icon 1.37%
$292.58
price up icon 2.26%
$155.99
price up icon 3.09%
ONC ONC
$279.00
price up icon 1.57%
Cap:     |  Volume (24h):