480.25
price down icon1.06%   -5.14
after-market After Hours: 480.25
loading
Vertex Pharmaceuticals Inc stock is traded at $480.25, with a volume of 1.15M. It is down -1.06% in the last 24 hours and up +7.94% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
See More
Previous Close:
$485.39
Open:
$486.175
24h Volume:
1.15M
Relative Volume:
0.79
Market Cap:
$121.89B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
28.47
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
-9.32%
1M Performance:
+7.94%
6M Performance:
+5.63%
1Y Performance:
+2.43%
1-Day Range:
Value
$474.71
$486.18
1-Week Range:
Value
$474.71
$533.67
52-Week Range:
Value
$362.50
$533.67

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-08-03
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, RVMD, ALNY

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
480.25 123.19B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
663.09 69.67B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
876.25 54.58B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
183.95 39.73B 742.00K -1.37B -1.07B -7.0731
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
288.06 39.89B 4.29B 577.22M 641.34M 4.2086

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

pulisher
06:00 AM

Vertex Pharmaceuticals (VRTX) Declines More Than Market: Some Information for Investors - Yahoo Finance Singapore

06:00 AM
pulisher
03:08 AM

Does Vertex's Acquisition of Crinetics Pharmaceuticals Make the Stock a No-Brainer Buy? - AOL.com

03:08 AM
pulisher
03:05 AM

VRTX Maintained by UBS -- Price Target Raised to $585 - GuruFocus

03:05 AM
pulisher
02:27 AM

Does Vertex's Acquisition of Crinetics Pharmaceuticals Make the Stock a No-Brainer Buy? - The Motley Fool

02:27 AM
pulisher
01:41 AM

VRTX Maintained by Truist Securities -- Price Target Raised to $560 - GuruFocus

01:41 AM
pulisher
09:57 AM

What to Expect From Vertex Pharmaceuticals' Next Quarterly Earnings Report - Barchart.com

09:57 AM
pulisher
09:14 AM

Truist raises Vertex stock price target to $560 on Crinetics deal - Investing.com

09:14 AM
pulisher
05:38 AM

Vertex Pharma stock holds steady as cystic fibrosis franchise underpins long-term growth outlook - ad-hoc-news.de

05:38 AM
pulisher
04:00 AM

Drugmaker Vertex spends $10B to buy biotech firm to expand rare-disease offerings - Post and Courier

04:00 AM
pulisher
12:52 PM

Vertex Pharmaceuticals (VRTX) Announces $10B Acquisition of Crinetics Pharmaceuticals - GuruFocus

12:52 PM
pulisher
Jul 12, 2026

The week in pharma: action, reaction and insight – week to July 10, 2026 - The Pharma Letter

Jul 12, 2026
pulisher
Jul 11, 2026

Vertex (VRTX) Wins FDA Expansion For CASGEVY And Advances ALYFTREK In Canada - Yahoo Finance

Jul 11, 2026
pulisher
Jul 11, 2026

Vertex Pharmaceuticals Bets $10 Billion on Crinetics to Build Endocrinology Powerhouse - Yahoo Finance

Jul 11, 2026
pulisher
Jul 11, 2026

Biotech Stocks Face Big $15B Hit as Vertex, Ionis Skew Flat Weekly Tape - TechStock²

Jul 11, 2026
pulisher
Jul 11, 2026

Vertex Pharmaceuticals (VRTX) Q1 2026 Earnings Call Transcript - Fortune

Jul 11, 2026
pulisher
Jul 10, 2026

Is This Biotech Stock a Buy Near Its 52-Week High? - The Motley Fool

Jul 10, 2026
pulisher
Jul 10, 2026

Vertex Pharmaceuticals Inc. stock underperforms Friday when compared to competitors - MarketWatch

Jul 10, 2026
pulisher
Jul 10, 2026

Crinetics Pharmaceuticals (CRNX) sets 1-year executive non-competes tied to Vertex deal - Stock Titan

Jul 10, 2026
pulisher
Jul 10, 2026

Why This Pharmaceutical Stock Jumped Close to 100% This Week - Yahoo Finance

Jul 10, 2026
pulisher
Jul 10, 2026

Weekly Buzz: JNJ, VERA Get FDA Nod; VRTX Snaps Up CRNX; MSLE Aces DMD Trial; IONS Misses Key Goal - RTTNews

Jul 10, 2026
pulisher
Jul 10, 2026

Nvidia, Vertex Pharmaceuticals And More On CNBC’s ‘Final Trades’ - Sahm

Jul 10, 2026
pulisher
Jul 10, 2026

Rx Rundown: Vertex Pharmaceuticals, Real Chemistry, Vera Therapeutics and more - Medical Marketing and Media

Jul 10, 2026
pulisher
Jul 10, 2026

A $10B deal, China trial scrutiny and highlights from ADA 2026 - Fierce Pharma

Jul 10, 2026
pulisher
Jul 10, 2026

If You Invested $1000 in Vertex Pharmaceuticals a Decade Ago, This is How Much It'd Be Worth Now - Yahoo Finance

Jul 10, 2026
pulisher
Jul 10, 2026

Vertex Pharmaceuticals Just Made a $10 Billion Move. Is the Stock a Buy? - The Motley Fool

Jul 10, 2026
pulisher
Jul 10, 2026

Vertex Pharmaceuticals Inc Stock Price Live, Charts & News - The Economic Times

Jul 10, 2026
pulisher
Jul 10, 2026

IBT portfolio manager: biotech M&A boom set to continue as big pharma hunts - Proactive financial news

Jul 10, 2026
pulisher
Jul 09, 2026

symbol__ Stock Quote Price and Forecast - CNN

Jul 09, 2026
pulisher
Jul 09, 2026

Crinetics Pharmaceuticals (CRNX) to be Acquired by Vertex Pharma - GuruFocus

Jul 09, 2026
pulisher
Jul 09, 2026

Vertex (VRTX) is One of the Best QQQ Stocks to Invest in - Yahoo Finance

Jul 09, 2026
pulisher
Jul 09, 2026

Why Crinetics Stock Soared 99% This Week - Yahoo Finance

Jul 09, 2026
pulisher
Jul 09, 2026

Lobbying Update: $60,000 of VERTEX PHARMACEUTICALS INCORPORATED lobbying was just disclosed - Quiver Quantitative

Jul 09, 2026
pulisher
Jul 09, 2026

CNBC ‘Final Trades’: Nvidia, Vertex Pharmaceuticals And More OnRoundhill Memory ETF (BATS:DRAM) - Benzinga

Jul 09, 2026
pulisher
Jul 09, 2026

Vertex acquires Crinetics in $10bn endocrinology deal - European Pharmaceutical Review

Jul 09, 2026
pulisher
Jul 09, 2026

Why Is Vertex Pharmaceuticals (NASDAQ:VRTX) Making Healthcare Headlines? - Kalkine Media

Jul 09, 2026
pulisher
Jul 08, 2026

Vertex’s $10 Billion Crinetics Acquisition Lands Amid Record Stock High: Time to Buy? - NAI500

Jul 08, 2026
pulisher
Jul 08, 2026

Vertex Pharmaceuticals Inc. stock underperforms Wednesday when compared to competitors - MarketWatch

Jul 08, 2026
pulisher
Jul 08, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Moved Down by 3.09% on Jul 8: Key Drivers Unveiled - TradingKey

Jul 08, 2026
pulisher
Jul 08, 2026

Crinetics Pharmaceuticals Investor Alert: Kahn Swick & Foti, LLC Investigates Adequacy of Price and Process in Proposed Sale of Crinetics Pharmaceuticals, Inc.CRNX - Business Wire

Jul 08, 2026
pulisher
Jul 08, 2026

Vertex Pharmaceutical agrees to buy Crinetics in US$10 billion deal - BNN Bloomberg

Jul 08, 2026
pulisher
Jul 08, 2026

Vertex’s Crinetics Deal Balances Growth with Integration Risk - MarketBeat

Jul 08, 2026
pulisher
Jul 08, 2026

PR News | Joele Frank Works Crinetics' $8.8B DealWed., Jul. 8, 2026 - O'Dwyer's PR

Jul 08, 2026
pulisher
Jul 08, 2026

Why Crinetics Pharmaceuticals Shares Are Trading Higher By 99%; Here Are 20 Stocks Moving Premarket - Sahm

Jul 08, 2026
pulisher
Jul 08, 2026

Stifel cuts Crinetics stock rating to hold on Vertex acquisition - Investing.com

Jul 08, 2026
pulisher
Jul 08, 2026

Vertex (VRTX) Stock May Be 36% Undervalued Following Its $10b Deal - Yahoo Finance

Jul 08, 2026
pulisher
Jul 08, 2026

American Vertex Pharmaceuticals acquires Crinetics for $10 billion - AKM.RU

Jul 08, 2026
pulisher
Jul 08, 2026

Collect 9.0% On VRTX Stock Now, And Still Keep 15% Of Upside - Trefis

Jul 08, 2026
pulisher
Jul 08, 2026

Jefferies Adjusts Vertex Pharmaceuticals Price Target to $610 From $580 - Moomoo

Jul 08, 2026
pulisher
Jul 08, 2026

Vertex Pharmaceuticals (VRTX) Buys Crinetics, Where Does Fair Value Sit Now? - Yahoo Finance

Jul 08, 2026
pulisher
Jul 08, 2026

H.C. Wainwright reiterates Vertex stock Buy rating at $641 target - Investing.com

Jul 08, 2026
pulisher
Jul 08, 2026

Analysts Offer Insights on Healthcare Companies: Aligos Therapeutics (ALGS) and Vertex Pharmaceuticals (VRTX) - The Globe and Mail

Jul 08, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading

Vertex Pharmaceuticals Inc Stock (VRTX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
McKechnie Duncan
EVP, Chief Commercial Officer
Jul 02 '26
Sale
519.00
1,541
799,779
11,001
Liu Joy
EVP and Chief Legal Officer
Jul 01 '26
Sale
502.71
828
416,244
19,131
$663.09
price down icon 0.22%
$876.25
price down icon 0.16%
$183.95
price down icon 1.57%
$288.06
price down icon 3.58%
ONC ONC
$303.96
price up icon 1.76%
Cap:     |  Volume (24h):