468.42
price up icon0.35%   1.63
after-market After Hours: 469.98 1.56 +0.33%
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Vertex Pharmaceuticals Inc stock is traded at $468.42, with a volume of 1.20M. It is up +0.35% in the last 24 hours and up +7.80% over the past month. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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Previous Close:
$466.79
Open:
$469.67
24h Volume:
1.20M
Relative Volume:
0.93
Market Cap:
$118.89B
Revenue:
$12.34B
Net Income/Loss:
$4.34B
P/E Ratio:
27.77
EPS:
16.8685
Net Cash Flow:
$3.71B
1W Performance:
+3.37%
1M Performance:
+7.80%
6M Performance:
+2.01%
1Y Performance:
+5.61%
1-Day Range:
Value
$463.75
$470.82
1-Week Range:
Value
$447.54
$470.82
52-Week Range:
Value
$362.50
$507.92

Vertex Pharmaceuticals Inc Stock (VRTX) Company Profile

Name
Name
Vertex Pharmaceuticals Inc
Name
Phone
(617) 341-6393
Name
Address
50 NORTHERN AVENUE, BOSTON, MA
Name
Employee
6,400
Name
Twitter
@VertexPharma
Name
Next Earnings Date
2026-08-03
Name
Latest SEC Filings
Name
VRTX's Discussions on Twitter

Compare VRTX vs REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
468.42 114.63B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
618.03 63.95B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
853.40 54.58B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
288.18 37.13B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
169.51 34.65B 742.00K -1.37B -1.07B -7.0731

Vertex Pharmaceuticals Inc Stock (VRTX) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-18-26 Upgrade Maxim Group Hold → Buy
Mar-10-26 Initiated Jefferies Buy
Mar-10-26 Reiterated Oppenheimer Outperform
Feb-13-26 Upgrade Oppenheimer Perform → Outperform
Jan-28-26 Resumed Barclays Overweight
Jan-22-26 Upgrade RBC Capital Mkts Sector Perform → Outperform
Jan-12-26 Upgrade Bernstein Mkt Perform → Outperform
Jan-07-26 Resumed UBS Buy
Jan-06-26 Upgrade Wolfe Research Peer Perform → Outperform
Dec-03-25 Upgrade Morgan Stanley Equal-Weight → Overweight
Nov-13-25 Initiated Scotiabank Sector Outperform
Sep-25-25 Upgrade Leerink Partners Market Perform → Outperform
Sep-03-25 Initiated Raymond James Mkt Perform
Aug-06-25 Upgrade Wells Fargo Equal Weight → Overweight
May-07-25 Downgrade Wolfe Research Outperform → Peer Perform
May-06-25 Downgrade Leerink Partners Outperform → Market Perform
Apr-22-25 Resumed Cantor Fitzgerald Overweight
Feb-12-25 Upgrade Canaccord Genuity Sell → Hold
Feb-11-25 Upgrade Canaccord Genuity Sell → Hold
Jan-30-25 Downgrade Wells Fargo Overweight → Equal Weight
Dec-20-24 Reiterated H.C. Wainwright Buy
Dec-19-24 Downgrade Oppenheimer Outperform → Perform
Dec-09-24 Upgrade Jefferies Hold → Buy
Nov-14-24 Initiated Citigroup Buy
Oct-16-24 Initiated Scotiabank Sector Perform
Oct-10-24 Resumed Raymond James Mkt Perform
Aug-05-24 Downgrade Barclays Overweight → Equal Weight
Jun-27-24 Initiated Redburn Atlantic Buy
Apr-11-24 Upgrade Evercore ISI In-line → Outperform
Feb-15-24 Initiated Wolfe Research Outperform
Feb-06-24 Downgrade Evercore ISI Outperform → In-line
Feb-02-24 Downgrade Bernstein Outperform → Mkt Perform
Jan-31-24 Downgrade Maxim Group Buy → Hold
Jan-31-24 Downgrade Robert W. Baird Neutral → Underperform
Jan-24-24 Downgrade Canaccord Genuity Hold → Sell
Dec-14-23 Reiterated RBC Capital Mkts Sector Perform
May-30-23 Initiated William Blair Outperform
May-04-23 Resumed Piper Sandler Overweight
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Hold
Jan-17-23 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-19-22 Downgrade Jefferies Buy → Hold
Jul-13-22 Initiated Cantor Fitzgerald Overweight
Jun-01-22 Upgrade Maxim Group Hold → Buy
May-23-22 Initiated SVB Leerink Mkt Perform
May-06-22 Downgrade Robert W. Baird Outperform → Neutral
May-03-22 Upgrade Morgan Stanley Underweight → Equal-Weight
Feb-03-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Jan-27-22 Reiterated JP Morgan Overweight
Jan-27-22 Reiterated Morgan Stanley Underweight
Jan-27-22 Reiterated RBC Capital Mkts Outperform
Jan-27-22 Reiterated Stifel Hold
Jan-27-22 Reiterated Wolfe Research Outperform
Jan-20-22 Upgrade BMO Capital Markets Market Perform → Outperform
Dec-09-21 Initiated Wells Fargo Overweight
Nov-19-21 Initiated BMO Capital Markets Market Perform
Nov-19-21 Downgrade Piper Sandler Overweight → Neutral
Sep-09-21 Downgrade Stifel Buy → Hold
Sep-07-21 Downgrade Morgan Stanley Equal-Weight → Underweight
Jul-20-21 Downgrade SVB Leerink Mkt Perform → Underperform
Jul-19-21 Resumed Wolfe Research Outperform
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-11-21 Downgrade Daiwa Securities Outperform → Neutral
Feb-23-21 Upgrade Robert W. Baird Neutral → Outperform
Feb-02-21 Reiterated H.C. Wainwright Buy
Dec-30-20 Initiated Daiwa Securities Outperform
Nov-30-20 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-20-20 Initiated Bernstein Outperform
Oct-28-20 Initiated UBS Buy
Jul-31-20 Reiterated H.C. Wainwright Buy
Jul-08-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Apr-30-20 Reiterated H.C. Wainwright Buy
Apr-28-20 Downgrade RBC Capital Mkts Outperform → Sector Perform
Mar-04-20 Initiated Barclays Overweight
Jan-31-20 Downgrade Robert W. Baird Outperform → Neutral
Nov-19-19 Upgrade Guggenheim Neutral → Buy
Nov-12-19 Initiated SunTrust Buy
Oct-17-19 Resumed BofA/Merrill Buy
Sep-03-19 Upgrade Goldman Neutral → Buy
Aug-01-19 Downgrade Needham Buy → Hold
May-23-19 Resumed Citigroup Buy
May-21-19 Initiated Credit Suisse Outperform
Apr-12-19 Initiated Evercore ISI In-line
Mar-26-19 Upgrade William Blair Mkt Perform → Outperform
Mar-19-19 Downgrade SVB Leerink Outperform → Mkt Perform
Feb-06-19 Downgrade Maxim Group Buy → Hold
View All

Vertex Pharmaceuticals Inc Stock (VRTX) Latest News

pulisher
01:05 AM

Vertex Pharma with clear analyst backing, shares supported by strong consensus estimates - AD HOC NEWS

01:05 AM
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09:12 AM

Vertex Pharmaceuticals (VRTX) Stock After Strong Multi‑Year Run Is The Price Still Reasonable - Yahoo Finance

09:12 AM
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08:08 AM

Positive Pediatric CASGEVY Data Might Change The Case For Investing In Vertex Pharmaceuticals (VRTX) - Yahoo Finance

08:08 AM
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08:00 AM

Questex’s PODD, the Premier Gathering for Drug Delivery Industry Leaders, Announces the 16th Annual Conference Agenda - GlobeNewswire Inc.

08:00 AM
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07:30 AM

Vertex Pharmaceuticals (NASDAQ:VRTX): A GARP Growth Stock with Reasonable Valuation and Strong Fundamentals - ChartMill

07:30 AM
pulisher
Jun 22, 2026

Vertex Pharmaceuticals Inc. stock underperforms Monday when compared to competitors despite daily gains - MarketWatch

Jun 22, 2026
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Jun 22, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Closed Up by 3.45% on Jun 22: What Signal Does It Send? - TradingKey

Jun 22, 2026
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Jun 22, 2026

A Loophole Brings Cystic Fibrosis Patients a ‘Miracle Drug’ in Generic Form - The New York Times

Jun 22, 2026
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Jun 22, 2026

2 Reasons to Like VRTX (and 1 Not So Much) - Yahoo Finance

Jun 22, 2026
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Jun 20, 2026

How Strong Pediatric CASGEVY Data Could Impact Vertex Pharmaceuticals’ (VRTX) Gene Therapy Investment Narrative - simplywall.st

Jun 20, 2026
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Jun 20, 2026

Vertex Has a Head Start in Non-Opioid Pain. Eli Lilly Just Spent Billions to Catch Up. Here's What That Means for Both Stocks. - The Motley Fool

Jun 20, 2026
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Jun 19, 2026

Vertex Pharma Stockweekly review in a strong biotech sector - AD HOC NEWS

Jun 19, 2026
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Jun 19, 2026

Can Vertex's Kidney Pipeline Power Its Next Growth Phase? - TradingView

Jun 19, 2026
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Jun 19, 2026

Nia Impact Solutions Fund's Vertex Pharmaceuticals Inc(VRTX) Holding History - GuruFocus

Jun 19, 2026
pulisher
Jun 18, 2026

Vertex Pharmaceuticals (VRTX) Stock Sinks As Market Gains: Here's Why - Yahoo Finance Singapore

Jun 18, 2026
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Jun 18, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors despite losses on the day - MarketWatch

Jun 18, 2026
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Jun 18, 2026

Insider Sell: Carmen Bozic Sells Shares of Vertex Pharmaceuticals Inc (VRTX) - GuruFocus

Jun 18, 2026
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Jun 17, 2026

Why the Market Dipped But Vertex Pharmaceuticals (VRTX) Gained Today - Yahoo Finance

Jun 17, 2026
pulisher
Jun 17, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Jun 17, 2026
pulisher
Jun 17, 2026

Here is What to Know Beyond Why Vertex Pharmaceuticals Incorporated (VRTX) is a Trending Stock - Yahoo Finance

Jun 17, 2026
pulisher
Jun 16, 2026

Vertex Pharmaceuticals CFO’s case for thinking like a portfolio manager - CFO.com

Jun 16, 2026
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Jun 16, 2026

Citi Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Maintains Target Price $585 - Moomoo

Jun 16, 2026
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Jun 16, 2026

Fierce Biotech Layoff Tracker 2026: enGene halves workforce; Neumora cuts 35% - Fierce Biotech

Jun 16, 2026
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Jun 15, 2026

Vertex Pharmaceuticals Inc. stock rises Monday, still underperforms market - MarketWatch

Jun 15, 2026
pulisher
Jun 15, 2026

Vertex Pharma (NASDAQ: VRTX) notice: 4,062 shares proposed for resale on 06/15/2026 - Stock Titan

Jun 15, 2026
pulisher
Jun 15, 2026

Vertex Pharma Stock (US92532F1003): Wall Street Analysts Lift Targets After VX-548 Progress - AD HOC NEWS

Jun 15, 2026
pulisher
Jun 14, 2026

Vertex Pharma Stock (US92532F1003): Analyst sentiment and ownership moves keep VRTX in focus - AD HOC NEWS

Jun 14, 2026
pulisher
Jun 13, 2026

Is It Time to Buy This Turnaround Pharma Stock? - NAI500

Jun 13, 2026
pulisher
Jun 12, 2026

Vertex Pharmaceuticals (VRTX) Receives a Buy from Wells Fargo - The Globe and Mail

Jun 12, 2026
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Jun 12, 2026

Swiss National Bank Reduces Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 12, 2026
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Jun 12, 2026

Meiji Yasuda America Inc Invests $1.91 Million in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 12, 2026
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Jun 12, 2026

Aviva PLC Buys 11,322 Shares of Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 12, 2026
pulisher
Jun 12, 2026

Vertex Extends Pediatric Pipeline As Shares Trade Below Consensus Targets - Yahoo Finance

Jun 12, 2026
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Jun 11, 2026

Vertex Pharmaceuticals (VRTX) Rises Higher Than Market: Key Facts - Yahoo Finance

Jun 11, 2026
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Jun 11, 2026

Is Vertex Pharmaceuticals Incorporated (VRTX) A Good Stock To Buy Now? - Insider Monkey

Jun 11, 2026
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Jun 11, 2026

Goldman Sachs Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Maintains Target Price $641 - Moomoo

Jun 11, 2026
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Jun 11, 2026

Vertex CASGEVY pediatric data shows 100% success in CRISPR trials - grafa.com

Jun 11, 2026
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Jun 11, 2026

Zions Bancorporation National Association UT Grows Stock Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 11, 2026
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Jun 11, 2026

Vertex Pharmaceuticals (VRTX) Reports Positive Data for Casgevy in Pediatrics - GuruFocus

Jun 11, 2026
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Jun 11, 2026

Illinois Municipal Retirement Fund Reduces Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 11, 2026
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Jun 11, 2026

LPL Financial LLC Has $125.53 Million Stake in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 11, 2026
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Jun 11, 2026

Vertex Presents New Data on CASGEVY®, Including First European Presentation of Data in Children Ages 5–11, at the European Hematology Association Congress and Announces Additional Global Regulatory Submissions - Business Wire

Jun 11, 2026
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Jun 11, 2026

MFS Blended Research Core Equity Portfolio's Vertex Pharmaceuticals Inc(VRTX) Holding History - GuruFocus

Jun 11, 2026
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Jun 10, 2026

Vertex Pharmaceuticals (VRTX) Declines More Than Market: Some Information for Investors - Yahoo Finance

Jun 10, 2026
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Jun 10, 2026

Vertex Pharmaceuticals Inc. stock underperforms Wednesday when compared to competitors - MarketWatch

Jun 10, 2026
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Jun 10, 2026

Vertex Pharmaceuticals stock (US92532F1003): Insider sale draws attention amid strong biotech pipeli - AD HOC NEWS

Jun 10, 2026
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Jun 10, 2026

VRTX: Pipeline momentum in CF, pain, and kidney disease drives innovation-led growth outlook - TradingView

Jun 10, 2026
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Jun 10, 2026

VRTX: Expanding CF, pain, and renal franchises with robust late-stage pipeline and innovation focus - TradingView

Jun 10, 2026
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Jun 10, 2026

Vertex Pharma stock (US92532F1003): focus on cystic fibrosis growth and pipeline potential - AD HOC NEWS

Jun 10, 2026
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Jun 10, 2026

Motley Fool Asset Management LLC Has $10.70 Million Holdings in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 10, 2026
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Jun 10, 2026

Motley Fool Wealth Management LLC Decreases Stock Position in Vertex Pharmaceuticals Incorporated $VRTX - MarketBeat

Jun 10, 2026

Vertex Pharmaceuticals Inc Stock (VRTX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$618.03
price up icon 0.90%
$853.40
price down icon 5.57%
$288.18
price up icon 0.62%
$169.51
price up icon 2.23%
ONC ONC
$276.13
price up icon 1.59%
Cap:     |  Volume (24h):