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Madrigal Pharmaceuticals Inc stock is traded at $510.04, with a volume of 379.18K. It is down -4.64% in the last 24 hours and down -1.87% over the past month. Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, liver cancer, need for liver transplantation and premature mortality. Its medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor beta agonist designed to target key underlying causes of MASH.
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Previous Close:
$534.86
Open:
$535
24h Volume:
379.18K
Relative Volume:
1.08
Market Cap:
$11.76B
Revenue:
$1.13B
Net Income/Loss:
$-309.44M
P/E Ratio:
-39.85
EPS:
-12.8001
Net Cash Flow:
$-275.41M
1W Performance:
-0.72%
1M Performance:
-1.87%
6M Performance:
+4.25%
1Y Performance:
+70.26%
1-Day Range:
Value
$510.00
$541.57
1-Week Range:
Value
$497.23
$559.00
52-Week Range:
Value
$265.00
$615.00

Madrigal Pharmaceuticals Inc Stock (MDGL) Company Profile

Name
Name
Madrigal Pharmaceuticals Inc
Name
Phone
404-380-9263
Name
Address
200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN, PA
Name
Employee
915
Name
Twitter
@MadrigalPharma
Name
Next Earnings Date
2026-05-06
Name
Latest SEC Filings
Name
MDGL's Discussions on Twitter

Compare MDGL vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
MDGL icon
MDGL
Madrigal Pharmaceuticals Inc
510.04 11.76B 1.13B -309.44M -275.41M -12.80
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
429.82 109.09B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
714.89 74.95B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
782.17 48.64B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
295.05 39.39B 4.29B 577.22M 641.34M 4.2086
ONC icon
ONC
Beone Medicines Ltd Adr
312.12 32.38B 5.36B 287.73M 924.18M 2.5229

Madrigal Pharmaceuticals Inc Stock (MDGL) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-28-26 Initiated Barclays Overweight
Jan-06-26 Downgrade Wolfe Research Outperform → Peer Perform
Nov-05-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-03-25 Upgrade BofA Securities Underperform → Neutral
Oct-15-25 Initiated Truist Buy
Sep-04-25 Resumed H.C. Wainwright Buy
Feb-28-25 Upgrade B. Riley Securities Neutral → Buy
Feb-27-25 Reiterated H.C. Wainwright Buy
Jun-28-24 Initiated Cantor Fitzgerald Neutral
Jun-11-24 Initiated Wolfe Research Outperform
Apr-22-24 Initiated BofA Securities Underperform
Mar-15-24 Upgrade B. Riley Securities Sell → Neutral
Mar-06-24 Initiated Citigroup Buy
Feb-26-24 Downgrade B. Riley Securities Neutral → Sell
Dec-20-22 Reiterated Oppenheimer Outperform
Dec-19-22 Reiterated H.C. Wainwright Buy
Dec-19-22 Reiterated Piper Sandler Overweight
Dec-19-22 Upgrade Raymond James Underperform → Mkt Perform
Jul-08-22 Downgrade B. Riley Securities Buy → Neutral
Oct-07-21 Initiated Jefferies Buy
Aug-06-21 Upgrade BMO Capital Markets Market Perform → Outperform
May-20-21 Resumed Goldman Buy
Nov-24-20 Resumed Evercore ISI Outperform
Nov-06-20 Reiterated H.C. Wainwright Buy
Jul-31-20 Initiated Piper Sandler Overweight
Jun-05-20 Initiated BMO Capital Markets Market Perform
May-05-20 Initiated Chardan Capital Markets Buy
Jan-30-20 Initiated Canaccord Genuity Buy
Jan-09-20 Upgrade UBS Neutral → Buy
Nov-07-19 Reiterated H.C. Wainwright Buy
Jun-25-19 Initiated Stifel Hold
Jun-10-19 Upgrade B. Riley FBR Neutral → Buy
Feb-28-19 Reiterated H.C. Wainwright Buy
Feb-22-19 Initiated SVB Leerink Outperform
Jan-23-19 Initiated UBS Neutral
Dec-14-18 Initiated Wolfe Research Outperform
Dec-12-18 Initiated B. Riley FBR Neutral
Nov-19-18 Downgrade Raymond James Mkt Perform → Underperform
Nov-16-18 Upgrade Evercore ISI In-line → Outperform
Sep-04-18 Initiated Citigroup Buy
Aug-06-18 Downgrade Goldman Buy → Neutral
Jun-28-18 Initiated Raymond James Mkt Perform
View All

Madrigal Pharmaceuticals Inc Stock (MDGL) Latest News

pulisher
May 09, 2026

Madrigal Pharmaceuticals, Inc. 2026 Q1ResultsEarnings Call Presentation (NASDAQ:MDGL) 2026-05-09 - Seeking Alpha

May 09, 2026
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May 08, 2026

Madrigal Pharmaceuticals (MDGL) Quarterly Loss Of US$94 Million Tests Bullish Margin Turnaround Narrative - Sahm

May 08, 2026
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May 08, 2026

MDGL Maintained by Canaccord Genuity -- Price Target Lowered to $578 - GuruFocus

May 08, 2026
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May 08, 2026

Madrigal (MDGL) Reports Strong Q1 Revenue and Positive Market Ou - GuruFocus

May 08, 2026
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May 07, 2026

MDGL Maintains Rating by Evercore ISI Group -- Price Target Lowe - GuruFocus

May 07, 2026
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May 07, 2026

47 new Madrigal hires get stock awards; options priced at $513.72 - Stock Titan

May 07, 2026
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May 07, 2026

Madrigal Q1 Earnings Beat, MASH Drug Sales Drive Top Line, Stock Up - Yahoo Finance

May 07, 2026
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May 07, 2026

Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) Q1 2026 Earnings Call Transcript - Insider Monkey

May 07, 2026
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May 07, 2026

Madrigal Q1 2026 slides: blockbuster Rezdiffra tops $1.1B in sales - Investing.com Australia

May 07, 2026
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May 07, 2026

Madrigal outlays $1bn for Arrowhead’s siRNA MASH asset - MSN

May 07, 2026
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May 07, 2026

Madrigal: Q1 Earnings Snapshot - theheraldreview.com

May 07, 2026
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May 07, 2026

MSN Money - MSN

May 07, 2026
pulisher
May 06, 2026

Madrigal sees 2026 gross-to-net in the mid- to high 30s while advancing F4c outcomes readout expected in 2027 - MSN

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals Q1 Earnings Call Highlights - Yahoo Finance

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals Q1 2026 Financial Results and Forward-Looking Statements – Rezdiffra Commercialization and Regulatory Updates - Minichart

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals Releases Q1 2026 Financial Results - AlphaStreet

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals Q1 2026 Earnings Call Transcript - MarketBeat

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals, Inc. Q1 2026 Earnings Call Summary - Yahoo Finance

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals Reports Blockbuster Rezdiffra Sales and Pipeline Expansion in Q1 2026 Financial Results - Minichart

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals Inc reports results for the quarter ended December 31Earnings Summary - TradingView

May 06, 2026
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May 06, 2026

Madrigal’s (MDGL) MASH Strategy Reiinforced By Rezdiffra Sales Growth and Pipeline Expansion - Yahoo Finance

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals, Inc. Reports Earnings Results for the First Quarter Ended March 31, 2026 - marketscreener.com

May 06, 2026
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May 06, 2026

Pharma M&A Roundup: Bayer to Acquire Perfuse Therapeutics, Madrigal Enters Licensing Agreement for ARO-PNPLA3 - Pharmaceutical Executive

May 06, 2026
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May 06, 2026

Earnings call transcript: Madrigal Pharmaceuticals Q1 2026 surprises with earnings beat - Investing.com

May 06, 2026
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May 06, 2026

Full Transcript: Madrigal Pharmaceuticals Q1 2026 Earnings Call - Benzinga

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals (NASDAQ: MDGL) grows Rezdiffra revenue but remains loss-making - Stock Titan

May 06, 2026
pulisher
May 06, 2026

Madrigal Pharmaceuticals (NASDAQ:MDGL) Shares Dip Despite Q1 2026 Earnings Beat and 127% Rezdiffra Revenue Growth - ChartMill

May 06, 2026
pulisher
May 06, 2026

Madrigal (MDGL) Reports Q1 Loss, Beats Revenue Estimates - Yahoo Finance Singapore

May 06, 2026
pulisher
May 06, 2026

Q1 2026 Madrigal Pharmaceuticals Inc Earnings Call Transcript - GuruFocus

May 06, 2026
pulisher
May 06, 2026

MADRIGAL PHARMACEUTICALS ($MDGL) Releases Q1 2026 Earnings - Quiver Quantitative

May 06, 2026
pulisher
May 06, 2026

Earnings Flash (MDGL) Madrigal Pharmaceuticals Posts Q1 Net Loss $3.25 a Share, Vs. FactSet Est of $4.23 Loss - Moomoo

May 06, 2026
pulisher
May 06, 2026

Madrigal Pharmaceuticals, Inc. announced that its drug interaction study for Ervogastat/Resmetirom is progressing steadily and is expected to officially launch in the fourth quarter of 2026. - Bitget

May 06, 2026
pulisher
May 06, 2026

42,250 patients use Rezdiffra as Madrigal adds MASH gene drug - Stock Titan

May 06, 2026
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May 06, 2026

Madrigal Pharmaceuticals, Inc. Announces Board Changes, Effective April 22, 2026 - marketscreener.com

May 06, 2026
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May 06, 2026

Rezdiffra powers Madrigal Pharmaceuticals (NASDAQ: MDGL) to 127% Q1 revenue growth - Stock Titan

May 06, 2026
pulisher
May 06, 2026

BRIEF-Madrigal Pharmaceuticals Q1 Product Revenue USD 311.337 Million - TradingView

May 06, 2026
pulisher
May 06, 2026

Madrigal Pharmaceuticals Reports First-Quarter 2026 Financial Results and Provides Corporate Updates - GlobeNewswire

May 06, 2026
pulisher
May 06, 2026

Arrowhead and Madrigal sign global licence for MASH RNAi therapy - Yahoo Finance

May 06, 2026
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May 06, 2026

Madrigal doubles down on MASH with second licensing deal - BioXconomy

May 06, 2026
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May 06, 2026

Madrigal Expands MASH Franchise With Precision RNAi License For ARO PNPLA3 - simplywall.st

May 06, 2026
pulisher
May 05, 2026

Should Madrigal’s ARO-PNPLA3 License Deal Reshape the MASH Strategy for Madrigal Pharmaceuticals (MDGL) Investors? - Yahoo Finance

May 05, 2026
pulisher
May 05, 2026

Madrigal Pharmaceuticals Q1 2026 earnings preview - MSN

May 05, 2026
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May 05, 2026

Madrigal Pharma Adds Another Genetic Medicine to Its Drug Combo Strategy in MASH - MedCity News

May 05, 2026
pulisher
May 05, 2026

Madrigal earnings on deck: Can Rezdiffra sustain blockbuster pace? - Investing.com

May 05, 2026
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May 05, 2026

Madrigal expands MASH pipeline in potential $1B Arrowhead deal - BioWorld News

May 05, 2026
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May 05, 2026

Madrigal picks up another siRNA asset for MASH, betting up to $1B with Arrowhead - BioSpace

May 05, 2026
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May 05, 2026

Madrigal Pharmaceuticals Inc announces exclusive global license for Aro-Pnpla3 from Arrowhead - marketscreener.com

May 05, 2026
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May 05, 2026

Arrowhead licenses MASH drug candidate to Madrigal for $1B By Investing.com - Investing.com South Africa

May 05, 2026
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May 05, 2026

Madrigal Adds Clinical-Stage siRNA Asset Targeting PNPLA3 to its MASH Pipeline - The Manila Times

May 05, 2026
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May 04, 2026

Biotechnology company Arrowhead Pharmaceuticals announces a major collaboration agreement with Madrigal Pharmaceuticals. - Bitget

May 04, 2026
pulisher
May 04, 2026

Madrigal Pharmaceuticals (MDGL) Stock Analysis: Exploring a 31% Upside Potential in the Biotech Sector - DirectorsTalk Interviews

May 04, 2026

Madrigal Pharmaceuticals Inc Stock (MDGL) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$54.35
price up icon 11.97%
$101.35
price down icon 3.48%
$50.79
price up icon 1.18%
$94.12
price up icon 1.19%
$141.81
price down icon 0.49%
ONC ONC
$312.12
price down icon 1.54%
Cap:     |  Volume (24h):