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Madrigal Pharmaceuticals Inc stock is traded at $471.75, with a volume of 312.98K. It is down -1.08% in the last 24 hours and down -13.70% over the past month. Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, liver cancer, need for liver transplantation and premature mortality. Its medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor beta agonist designed to target key underlying causes of MASH.
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Previous Close:
$476.91
Open:
$477.48
24h Volume:
312.98K
Relative Volume:
1.11
Market Cap:
$10.90B
Revenue:
$1.13B
Net Income/Loss:
$-309.44M
P/E Ratio:
-36.86
EPS:
-12.8001
Net Cash Flow:
$-275.41M
1W Performance:
-5.54%
1M Performance:
-13.70%
6M Performance:
-10.02%
1Y Performance:
+10.14%
1-Day Range:
Value
$470.53
$483.63
1-Week Range:
Value
$466.06
$505.00
52-Week Range:
Value
$393.61
$615.00

Madrigal Pharmaceuticals Inc Stock (MDGL) Company Profile

Name
Name
Madrigal Pharmaceuticals Inc
Name
Phone
404-380-9263
Name
Address
200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN, PA
Name
Employee
915
Name
Twitter
@MadrigalPharma
Name
Next Earnings Date
2026-11-03
Name
Latest SEC Filings
Name
MDGL's Discussions on Twitter

Compare MDGL vs VRTX, MRNA, REGN, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
MDGL icon
MDGL
Madrigal Pharmaceuticals Inc
471.75 10.90B 1.13B -309.44M -275.41M -12.80
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
510.08 129.29B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
225.00 89.83B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
746.54 76.86B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
825.03 51.88B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
189.76 40.67B 742.00K -1.37B -1.07B -7.0731

Madrigal Pharmaceuticals Inc Stock (MDGL) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-24-26 Resumed Goldman Buy
Sep-23-26 Initiated Citigroup Buy
Aug-04-26 Upgrade Wolfe Research Peer Perform → Outperform
Jul-27-26 Initiated Wells Fargo Overweight
Jan-28-26 Initiated Barclays Overweight
Jan-06-26 Downgrade Wolfe Research Outperform → Peer Perform
Nov-05-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-03-25 Upgrade BofA Securities Underperform → Neutral
Oct-15-25 Initiated Truist Buy
Sep-04-25 Resumed H.C. Wainwright Buy
Feb-28-25 Upgrade B. Riley Securities Neutral → Buy
Feb-27-25 Reiterated H.C. Wainwright Buy
Jun-28-24 Initiated Cantor Fitzgerald Neutral
Jun-11-24 Initiated Wolfe Research Outperform
Apr-22-24 Initiated BofA Securities Underperform
Mar-15-24 Upgrade B. Riley Securities Sell → Neutral
Mar-06-24 Initiated Citigroup Buy
Feb-26-24 Downgrade B. Riley Securities Neutral → Sell
Dec-20-22 Reiterated Oppenheimer Outperform
Dec-19-22 Reiterated H.C. Wainwright Buy
Dec-19-22 Reiterated Piper Sandler Overweight
Dec-19-22 Upgrade Raymond James Underperform → Mkt Perform
Jul-08-22 Downgrade B. Riley Securities Buy → Neutral
Oct-07-21 Initiated Jefferies Buy
Aug-06-21 Upgrade BMO Capital Markets Market Perform → Outperform
May-20-21 Resumed Goldman Buy
Nov-24-20 Resumed Evercore ISI Outperform
Nov-06-20 Reiterated H.C. Wainwright Buy
Jul-31-20 Initiated Piper Sandler Overweight
Jun-05-20 Initiated BMO Capital Markets Market Perform
May-05-20 Initiated Chardan Capital Markets Buy
Jan-30-20 Initiated Canaccord Genuity Buy
Jan-09-20 Upgrade UBS Neutral → Buy
Nov-07-19 Reiterated H.C. Wainwright Buy
Jun-25-19 Initiated Stifel Hold
Jun-10-19 Upgrade B. Riley FBR Neutral → Buy
Feb-28-19 Reiterated H.C. Wainwright Buy
Feb-22-19 Initiated SVB Leerink Outperform
Jan-23-19 Initiated UBS Neutral
Dec-14-18 Initiated Wolfe Research Outperform
Dec-12-18 Initiated B. Riley FBR Neutral
Nov-19-18 Downgrade Raymond James Mkt Perform → Underperform
Nov-16-18 Upgrade Evercore ISI In-line → Outperform
Sep-04-18 Initiated Citigroup Buy
Aug-06-18 Downgrade Goldman Buy → Neutral
Jun-28-18 Initiated Raymond James Mkt Perform
View All

Madrigal Pharmaceuticals Inc Stock (MDGL) Latest News

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Oct 07, 2026

Can NVO's Semaglutide Push Create Growth Beyond Cardiometabolic Care? - Zacks Investment Research

Oct 07, 2026
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Oct 07, 2026

Madrigal Pharmaceuticals stock gets fresh Rezdiffra data - AD HOC NEWS

Oct 07, 2026
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Oct 06, 2026

A liver drug improved disease measures across several genetic risk groups - Stock Titan

Oct 06, 2026
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Sep 28, 2026

Under an automatic trading plan, director Paul Friedman proposes to sell shares in Madrigal Pharmaceuticals (MDGL). - Stock Titan

Sep 28, 2026
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Sep 21, 2026

Madrigal Grants Equity Awards to 27 New Employees - MyChesCo

Sep 21, 2026
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Sep 16, 2026

Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4) - GlobeNewswire

Sep 16, 2026
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Sep 16, 2026

Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4) - Yahoo Finance

Sep 16, 2026
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Sep 11, 2026

Understanding Momentum Shifts in (MDGL) - Stock Traders Daily

Sep 11, 2026
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Sep 11, 2026

Madrigal Pharmaceuticals (NASDAQ: MDGL) insider plans another stock sale after recent multimillion-dollar trades - stocktitan.net

Sep 11, 2026
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Sep 11, 2026

Madrigal Pharma CEO William John Sibold disposes of common shares worth $4.16 million - Bitget

Sep 11, 2026
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Sep 10, 2026

Madrigal Pharmaceuticals, Inc. Rings the Nasdaq Stock Market Closing Bell - Nasdaq

Sep 10, 2026
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Sep 10, 2026

Madrigal at cantor healthcare conference: growth, access and pipeline By Investing.com - Investing.com Nigeria

Sep 10, 2026
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Sep 10, 2026

Madrigal at cantor healthcare conference: growth, access and pipeline By Investing.com - Investing.com Canada

Sep 10, 2026
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Sep 10, 2026

Madrigal at cantor healthcare conference: growth, access and pipeline - investing.com

Sep 10, 2026
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Sep 10, 2026

Madrigal at cantor healthcare conference: growth, access and pipeline By Investing.com - Investing.com UK

Sep 10, 2026
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Sep 10, 2026

Institutional Investors Are Loading Up on Madrigal Pharmaceuticals Stock. Should You? - Yahoo Finance

Sep 10, 2026
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Sep 10, 2026

Madrigal Pharmaceuticals, Inc. Rings the Closing Bell - Nasdaq

Sep 10, 2026
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Sep 09, 2026

Madrigal Pharmaceuticals (NASDAQ: MDGL) exec plans $3.4M stock sale for tax withholding - stocktitan.net

Sep 09, 2026
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Sep 07, 2026

September 2026 Nasdaq Stock Market Bell Ceremonies - Nasdaq

Sep 07, 2026
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Sep 07, 2026

Madrigal Pharmaceuticals (MDGL) Stock Analysis: A 25% Upside Potential In Biotech Innovation - DirectorsTalk Interviews

Sep 07, 2026
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Sep 06, 2026

Madrigal to Put MASH Drug Strategy Before Investors at Cantor - MyChesCo

Sep 06, 2026
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Sep 02, 2026

Madrigal Pharmaceuticals (MDGL) Leads Healthcare CapEx Growth Am - GuruFocus

Sep 02, 2026
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Sep 02, 2026

Madrigal Pharmaceuticals to Participate in the 2026 Cantor Global Healthcare Conference - manilatimes.net

Sep 02, 2026
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Sep 02, 2026

Madrigal Pharmaceuticals to Participate in the 2026 Cantor Global Healthcare Conference - GlobeNewswire

Sep 02, 2026
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Sep 02, 2026

Madrigal Pharmaceuticals to Participate in the 2026 Cantor Global Healthcare Conference - Yahoo Finance

Sep 02, 2026
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Aug 31, 2026

Madrigal Pharmaceuticals, Inc. (MDGL) Stock Analysis: A 27% Upside Potential Amid Biotech Innovation - DirectorsTalk Interviews

Aug 31, 2026
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Aug 26, 2026

Madrigal Grants Stock Awards to 13 New Employees - MyChesCo

Aug 26, 2026
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Aug 25, 2026

Here's Exactly What It Will Take for Madrigal Pharmaceuticals Stock to Take Off - Yahoo Finance

Aug 25, 2026
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Aug 24, 2026

Madrigal Pharmaceuticals, Inc. (MDGL) Stock Report: Analysts See 31% Upside Potential with Strong Buy Ratings - DirectorsTalk Interviews

Aug 24, 2026
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Aug 21, 2026

When Will Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) Become Profitable? - 富途牛牛

Aug 21, 2026
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Aug 20, 2026

Madrigal Pharmaceuticals' General Counsel Executes Automatic Sale of 664 Shares to Cover Tax Withholding - Kalkine Media

Aug 20, 2026
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Aug 20, 2026

Shannon Kelley Sells 664 Shares of Madrigal Pharmaceuticals (NASDAQ:MDGL) Stock - MarketBeat

Aug 20, 2026
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Aug 20, 2026

Madrigal Pharmaceuticals Announces Grants Of Inducement Awards Under Nasdaq Listing Rule - TradingView

Aug 20, 2026
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Aug 20, 2026

Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4) - The Manila Times

Aug 20, 2026
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Aug 20, 2026

Madrigal (NASDAQ: MDGL) GC has 664 shares sold for RSU taxes - stocktitan.net

Aug 20, 2026
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Aug 20, 2026

Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4) - Yahoo Finance

Aug 20, 2026
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Aug 20, 2026

Madrigal (NASDAQ: MDGL) officer plans $337K sell-to-cover trade - stocktitan.net

Aug 20, 2026
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Aug 19, 2026

Madrigal Pharmaceuticals (MDGL) Stock May Look Cheap On Sales But Risky On Cash Flow - simplywall.st

Aug 19, 2026
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Aug 19, 2026

Exploring 3 High Growth Tech Stocks In The US Market - Sahm

Aug 19, 2026
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Aug 18, 2026

Madrigal Adds J&J R&D Chief to Board as MASH Push Expands - MyChesCo

Aug 18, 2026
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Aug 18, 2026

Madrigal (NASDAQ: MDGL) awards Reed 647 RSUs and options on 1,078 shares - stocktitan.net

Aug 18, 2026
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Aug 17, 2026

Madrigal Pharmaceuticals, Inc. (MDGL) Stock Analysis: A Biotech Powerhouse with 33.59% Upside Potential - DirectorsTalk Interviews

Aug 17, 2026
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Aug 16, 2026

2,410 Shares in Madrigal Pharmaceuticals, Inc. $MDGL Acquired by State of Wyoming - MarketBeat

Aug 16, 2026
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Aug 15, 2026

Madrigal’s Rezdiffra Hits $1.3B Run Rate as MASH Pipeline Expands - MarketBeat

Aug 15, 2026
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Aug 15, 2026

Madrigal’s Rezdiffra Hits $1.3B Run Rate as MASH Pipeline Expands - Yahoo Finance

Aug 15, 2026
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Aug 14, 2026

Madrigal Uses Equity Awards to Recruit 10 Employees - MyChesCo

Aug 14, 2026
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Aug 14, 2026

Madrigal Pharmaceuticals Inc (0JXI) Q1 2025 Earnings ReportResults, Call & Slides - TipRanks

Aug 14, 2026
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Aug 13, 2026

Madrigal Pharmaceuticals Adds Renowned Leader to Board - The Globe and Mail

Aug 13, 2026
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Aug 13, 2026

Dimensional Fund Advisors LP Has $4.46 Million Stock Holdings in Madrigal Pharmaceuticals, Inc. $MDGL - MarketBeat

Aug 13, 2026
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Aug 12, 2026

Madrigal Pharmaceuticals Appoints Dr. John C. Reed to Expanded Board with Detailed Compensation Plan - Kalkine Media

Aug 12, 2026

Madrigal Pharmaceuticals Inc Stock (MDGL) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Madrigal Pharmaceuticals Inc Stock (MDGL) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Sibold William John
President and CEO
Sep 11 '26
Sale
542.39
5,221
2,831,801
197,746
WILLIAM SIBOLD
Director
Sep 11 '26
Proposed Sale
533.12
5,221
2,783,420
0
William John Sibold
Officer and Director
Sep 09 '26
Proposed Sale
534.16
6,362
3,398,326
0
Sibold William John
President and CEO
Sep 09 '26
Sale
535.59
6,362
3,407,397
202,967
Kelley Shannon T
General Counsel
Aug 17 '26
Sale
514.97
664
341,940
11,474
Shannon Kelley
Officer
Aug 17 '26
Proposed Sale
507.56
664
337,020
0
Sibold William John
President and CEO
Jul 20 '26
Sale
547.30
2,500
1,368,253
209,329
William Sibold
Officer and Director
Jul 20 '26
Proposed Sale
553.48
2,500
1,383,700
0
Soergel David
Chief Medical Officer
Jun 01 '26
Sale
495.74
1,042
516,561
10,033
DAVID SOERGEL
Officer
Jun 01 '26
Proposed Sale
497.27
1,042
518,155
0
$10.51
price up icon 6.05%
$71.38
price up icon 9.79%
$54.80
price down icon 0.17%
$159.78
price up icon 5.08%
$72.46
price up icon 0.01%
$331.61
price up icon 1.32%
Cap:     |  Volume (24h):