492.83
price up icon0.96%   4.68
after-market After Hours: 475.00 -17.83 -3.62%
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Madrigal Pharmaceuticals Inc stock is traded at $492.83, with a volume of 219.10K. It is up +0.96% in the last 24 hours and down -4.98% over the past month. Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, liver cancer, need for liver transplantation and premature mortality. Its medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor beta agonist designed to target key underlying causes of MASH.
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Previous Close:
$488.15
Open:
$495.32
24h Volume:
219.10K
Relative Volume:
0.70
Market Cap:
$11.36B
Revenue:
$1.13B
Net Income/Loss:
$-309.44M
P/E Ratio:
-38.50
EPS:
-12.8001
Net Cash Flow:
$-275.41M
1W Performance:
-4.48%
1M Performance:
-4.98%
6M Performance:
-16.62%
1Y Performance:
+76.44%
1-Day Range:
Value
$486.17
$497.83
1-Week Range:
Value
$445.20
$520.30
52-Week Range:
Value
$271.95
$615.00

Madrigal Pharmaceuticals Inc Stock (MDGL) Company Profile

Name
Name
Madrigal Pharmaceuticals Inc
Name
Phone
404-380-9263
Name
Address
200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN, PA
Name
Employee
915
Name
Twitter
@MadrigalPharma
Name
Next Earnings Date
2026-05-06
Name
Latest SEC Filings
Name
MDGL's Discussions on Twitter

Compare MDGL vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
MDGL icon
MDGL
Madrigal Pharmaceuticals Inc
492.83 11.25B 1.13B -309.44M -275.41M -12.80
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
441.74 108.72B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
628.73 64.89B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
842.27 50.57B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
303.64 39.06B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
155.69 33.16B 742.00K -1.37B -1.07B -7.0731

Madrigal Pharmaceuticals Inc Stock (MDGL) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-28-26 Initiated Barclays Overweight
Jan-06-26 Downgrade Wolfe Research Outperform → Peer Perform
Nov-05-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-03-25 Upgrade BofA Securities Underperform → Neutral
Oct-15-25 Initiated Truist Buy
Sep-04-25 Resumed H.C. Wainwright Buy
Feb-28-25 Upgrade B. Riley Securities Neutral → Buy
Feb-27-25 Reiterated H.C. Wainwright Buy
Jun-28-24 Initiated Cantor Fitzgerald Neutral
Jun-11-24 Initiated Wolfe Research Outperform
Apr-22-24 Initiated BofA Securities Underperform
Mar-15-24 Upgrade B. Riley Securities Sell → Neutral
Mar-06-24 Initiated Citigroup Buy
Feb-26-24 Downgrade B. Riley Securities Neutral → Sell
Dec-20-22 Reiterated Oppenheimer Outperform
Dec-19-22 Reiterated H.C. Wainwright Buy
Dec-19-22 Reiterated Piper Sandler Overweight
Dec-19-22 Upgrade Raymond James Underperform → Mkt Perform
Jul-08-22 Downgrade B. Riley Securities Buy → Neutral
Oct-07-21 Initiated Jefferies Buy
Aug-06-21 Upgrade BMO Capital Markets Market Perform → Outperform
May-20-21 Resumed Goldman Buy
Nov-24-20 Resumed Evercore ISI Outperform
Nov-06-20 Reiterated H.C. Wainwright Buy
Jul-31-20 Initiated Piper Sandler Overweight
Jun-05-20 Initiated BMO Capital Markets Market Perform
May-05-20 Initiated Chardan Capital Markets Buy
Jan-30-20 Initiated Canaccord Genuity Buy
Jan-09-20 Upgrade UBS Neutral → Buy
Nov-07-19 Reiterated H.C. Wainwright Buy
Jun-25-19 Initiated Stifel Hold
Jun-10-19 Upgrade B. Riley FBR Neutral → Buy
Feb-28-19 Reiterated H.C. Wainwright Buy
Feb-22-19 Initiated SVB Leerink Outperform
Jan-23-19 Initiated UBS Neutral
Dec-14-18 Initiated Wolfe Research Outperform
Dec-12-18 Initiated B. Riley FBR Neutral
Nov-19-18 Downgrade Raymond James Mkt Perform → Underperform
Nov-16-18 Upgrade Evercore ISI In-line → Outperform
Sep-04-18 Initiated Citigroup Buy
Aug-06-18 Downgrade Goldman Buy → Neutral
Jun-28-18 Initiated Raymond James Mkt Perform
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Madrigal Pharmaceuticals Inc Stock (MDGL) Latest News

pulisher
04:05 AM

Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4) - Yahoo Finance

04:05 AM
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05:28 AM

Madrigal (MDGL) Data Highlights Rezdiffra’s Cardiometabolic Benefits for MASH Patients at EASL Congress - Insider Monkey

05:28 AM
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Jun 03, 2026

Madrigal Pharmaceuticals to Participate in the 47th Annual Global Goldman Sachs Health Care Conference 2026 - GlobeNewswire

Jun 03, 2026
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Jun 03, 2026

12 Best High Short Interest Stocks With Highest Upside Potential - Insider Monkey

Jun 03, 2026
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Jun 02, 2026

Madrigal Pharmaceuticals targets liver disease with Rezdiffra, eyeing strong growth despite competition risks. - Pluang

Jun 02, 2026
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Jun 02, 2026

Madrigal Pharmaceuticals Stock Could Become The Next Vertex (NASDAQ:MDGL) - Seeking Alpha

Jun 02, 2026
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Jun 02, 2026

Assessing Madrigal Pharmaceuticals (MDGL) Valuation After Recent Share Price Weakness - Yahoo Finance

Jun 02, 2026
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Jun 02, 2026

Madrigal Pharmaceuticals (MDGL) slides as insider sale headlines hit and investors take profits - Quiver Quantitative

Jun 02, 2026
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Jun 01, 2026

Insider Sell: David Soergel Sells Shares of Madrigal Pharmaceuticals Inc (MDGL) - GuruFocus

Jun 01, 2026
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Jun 01, 2026

Madrigal Pharmaceuticals CMO David Soergel sells $516,561 in shares By Investing.com - Investing.com Nigeria

Jun 01, 2026
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Jun 01, 2026

Madrigal Pharmaceuticals CMO David Soergel sells $516,561 in shares - Investing.com

Jun 01, 2026
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Jun 01, 2026

Madrigal (MDGL) CMO sells 1,042 shares in 10b5-1 trade, holds 10,033 - Stock Titan

Jun 01, 2026
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Jun 01, 2026

MDGL (NASDAQ) insider files Form 144 reporting sale of 1,042 shares - Stock Titan

Jun 01, 2026
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Jun 01, 2026

Citizens reiterates Madrigal Pharmaceuticals stock rating on liver data By Investing.com - Investing.com Canada

Jun 01, 2026
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Jun 01, 2026

Madrigal Pharmaceuticals, Inc. (MDGL): Investor Outlook Reveals 35.71% Potential Upside - DirectorsTalk Interviews

Jun 01, 2026
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May 29, 2026

Has Madrigal Pharmaceuticals (MDGL) Cracked the Code for MASH - Kavout

May 29, 2026
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May 28, 2026

H.C. Wainwright Maintains Madrigal Pharmaceuticals(MDGL.US) With Buy Rating, Maintains Target Price $620 - Moomoo

May 28, 2026
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May 27, 2026

Madrigal Pharmaceuticals (MDGL) Reports Positive Findings on Rez - GuruFocus

May 27, 2026
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May 27, 2026

Madrigal Pharmaceuticals Says Data Show Rezdiffra Reduces Cardiovascular, Liver-Related Risks in MASH Patients - Moomoo

May 27, 2026
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May 27, 2026

Madrigal Pharmaceuticals (MDGL) Reports Positive Findings on Rezdiffra for MASH Treatment - GuruFocus

May 27, 2026
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May 27, 2026

Madrigal Presents Data Demonstrating Rezdiffra Reduced Markers of Cardiovascular and Liver-Related Risk in Patients with MASH - The Manila Times

May 27, 2026
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May 27, 2026

Madrigal Presents Data Demonstrating Rezdiffra Reduced - GlobeNewswire

May 27, 2026
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May 27, 2026

MASH drug Rezdiffra lowered key heart and liver risk signals - Stock Titan

May 27, 2026
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May 26, 2026

Madrigal Pharmaceuticals Insider Sold Shares Worth $2,928,716, According to a Recent SEC Filing - Moomoo

May 26, 2026
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May 25, 2026

(MDGL) as a Liquidity Pulse for Institutional Tactics - Stock Traders Daily

May 25, 2026
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May 25, 2026

Madrigal Pharmaceuticals, Inc. (MDGL) Stock Analysis: A 30% Upside Beckons in the Biotech Sector - DirectorsTalk Interviews

May 25, 2026
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May 24, 2026

MDGL Stock Price Prediction 2025-2026 | Madrigal Pharmaceuticals Inc Forecast - 24/7 Wall St.

May 24, 2026
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May 22, 2026

Insider Sell: Richard Levy Sells Shares of Madrigal Pharmaceuticals Inc (MDGL) - GuruFocus

May 22, 2026
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May 22, 2026

Director Richard Levy of Madrigal (MDGL) sells 5,682 shares under plan - Stock Titan

May 22, 2026
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May 22, 2026

[144] MADRIGAL PHARMACEUTICALS, INC. SEC Filing - Stock Titan

May 22, 2026
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May 21, 2026

Madrigal Pharmaceuticals Inc (FRA:YDO1) Stock Price & 30 Year Financial Data - GuruFocus

May 21, 2026
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May 21, 2026

Madrigal hires 15 staff, grants 5,308 stock units vesting over 4 years - Stock Titan

May 21, 2026
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May 20, 2026

Madrigal to present Rezdiffra data at EASL Congress 2026 - Investing.com UK

May 20, 2026
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May 20, 2026

Madrigal to present Rezdiffra data at EASL Congress 2026 By Investing.com - Investing.com South Africa

May 20, 2026
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May 20, 2026

Madrigal to Present New Data from the Company’s MASH Program at EASL 2026 Demonstrating the Effects of Rezdiffra on Markers of Cardiovascular and Portal Hypertension Risk - GlobeNewswire

May 20, 2026
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May 20, 2026

Liver disease drug Rezdiffra shows new data on heart risk markers - Stock Titan

May 20, 2026
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May 18, 2026

Madrigal (NASDAQ: MDGL) CMO has 844 shares sold automatically for tax withholding - Stock Titan

May 18, 2026
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May 18, 2026

Insider sale notice: MDGL (NASDAQ: MDGL) 844 shares via Morgan Stanley - Stock Titan

May 18, 2026
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May 18, 2026

Madrigal Pharmaceuticals (MDGL) Investor Outlook: Significant Potential Upside with a 28.77% Gain on the Horizon - DirectorsTalk Interviews

May 18, 2026
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May 18, 2026

What Madrigal Pharmaceuticals (MDGL)'s Wider Q1 Losses and Rezdiffra Revenue Momentum Mean For Shareholders - Sahm

May 18, 2026
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May 17, 2026

Madrigal Pharmaceuticals Issues Equity Awards to 47 New Hires - MyChesCo

May 17, 2026
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May 17, 2026

Arrowhead Licenses ARO PNPLA3 To Madrigal To Expand MASH Options - Sahm

May 17, 2026
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May 15, 2026

Paulson & Co. (MDGL) holds 1.39M shares, representing 6.1% of Madrigal - Stock Titan

May 15, 2026
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May 15, 2026

Madrigal Rezdiffra Sales More Than Double in First Quarter - MyChesCo

May 15, 2026
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May 15, 2026

Janus Henderson (MDGL) discloses 2,018,647-share stake, 8.8% ownership - Stock Titan

May 15, 2026
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May 14, 2026

Madrigal outlays $1bn for Arrowhead’s siRNA MASH asset - MSN

May 14, 2026
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May 14, 2026

Madrigal Pharma Stock Sees Buyout Hype – Retail Predicts ‘Huge’ Deal On Liver Disease Drug Momentum - MSN

May 14, 2026
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May 14, 2026

Madrigal Licenses Arrowhead Drug Candidate for MASH - MyChesCo

May 14, 2026
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May 14, 2026

Number of shareholders of Madrigal Pharmaceuticals, Inc. – GETTEX:YDO1 - TradingView

May 14, 2026
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May 14, 2026

(MDGL) Risk Channels and Responsive Allocation - Stock Traders Daily

May 14, 2026
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May 14, 2026

Madrigal’s (MDGL) MASH Strategy Reiinforced By Rezdiffra Sales Growth and Pipeline Expansion - MSN

May 14, 2026

Madrigal Pharmaceuticals Inc Stock (MDGL) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$29.53
price up icon 2.89%
$89.59
price up icon 1.29%
$104.92
price up icon 1.02%
$55.02
price up icon 0.09%
ONC ONC
$279.93
price up icon 0.33%
$155.69
price down icon 0.19%
Cap:     |  Volume (24h):