435.01
price down icon1.13%   -4.99
after-market After Hours: 435.01
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Madrigal Pharmaceuticals Inc stock is traded at $435.01, with a volume of 656.09K. It is down -1.13% in the last 24 hours and down -9.46% over the past month. Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, and premature mortality. The company's medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor agonist designed to target key underlying causes of MASH.
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Previous Close:
$440.00
Open:
$440
24h Volume:
656.09K
Relative Volume:
1.91
Market Cap:
$9.88B
Revenue:
-
Net Income/Loss:
$-518.67M
P/E Ratio:
-17.32
EPS:
-25.12
Net Cash Flow:
$-438.32M
1W Performance:
-11.49%
1M Performance:
-9.46%
6M Performance:
+5.53%
1Y Performance:
+40.56%
1-Day Range:
Value
$434.67
$447.00
1-Week Range:
Value
$424.20
$461.98
52-Week Range:
Value
$265.00
$615.00

Madrigal Pharmaceuticals Inc Stock (MDGL) Company Profile

Name
Name
Madrigal Pharmaceuticals Inc
Name
Phone
404-380-9263
Name
Address
200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN, PA
Name
Employee
528
Name
Twitter
@MadrigalPharma
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
MDGL's Discussions on Twitter

Compare MDGL vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
MDGL
Madrigal Pharmaceuticals Inc
435.01 9.99B 0 -518.67M -438.32M -25.12
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
483.05 123.82B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
784.28 81.64B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
816.95 52.00B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
327.36 44.14B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
352.23 40.83B 4.98B 69.60M 525.67M 0.5198

Madrigal Pharmaceuticals Inc Stock (MDGL) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-28-26 Initiated Barclays Overweight
Jan-06-26 Downgrade Wolfe Research Outperform → Peer Perform
Nov-05-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-03-25 Upgrade BofA Securities Underperform → Neutral
Oct-15-25 Initiated Truist Buy
Sep-04-25 Resumed H.C. Wainwright Buy
Feb-28-25 Upgrade B. Riley Securities Neutral → Buy
Feb-27-25 Reiterated H.C. Wainwright Buy
Jun-28-24 Initiated Cantor Fitzgerald Neutral
Jun-11-24 Initiated Wolfe Research Outperform
Apr-22-24 Initiated BofA Securities Underperform
Mar-15-24 Upgrade B. Riley Securities Sell → Neutral
Mar-06-24 Initiated Citigroup Buy
Feb-26-24 Downgrade B. Riley Securities Neutral → Sell
Dec-20-22 Reiterated Oppenheimer Outperform
Dec-19-22 Reiterated H.C. Wainwright Buy
Dec-19-22 Reiterated Piper Sandler Overweight
Dec-19-22 Upgrade Raymond James Underperform → Mkt Perform
Jul-08-22 Downgrade B. Riley Securities Buy → Neutral
Oct-07-21 Initiated Jefferies Buy
Aug-06-21 Upgrade BMO Capital Markets Market Perform → Outperform
May-20-21 Resumed Goldman Buy
Nov-24-20 Resumed Evercore ISI Outperform
Nov-06-20 Reiterated H.C. Wainwright Buy
Jul-31-20 Initiated Piper Sandler Overweight
Jun-05-20 Initiated BMO Capital Markets Market Perform
May-05-20 Initiated Chardan Capital Markets Buy
Jan-30-20 Initiated Canaccord Genuity Buy
Jan-09-20 Upgrade UBS Neutral → Buy
Nov-07-19 Reiterated H.C. Wainwright Buy
Jun-25-19 Initiated Stifel Hold
Jun-10-19 Upgrade B. Riley FBR Neutral → Buy
Feb-28-19 Reiterated H.C. Wainwright Buy
Feb-22-19 Initiated SVB Leerink Outperform
Jan-23-19 Initiated UBS Neutral
Dec-14-18 Initiated Wolfe Research Outperform
Dec-12-18 Initiated B. Riley FBR Neutral
Nov-19-18 Downgrade Raymond James Mkt Perform → Underperform
Nov-16-18 Upgrade Evercore ISI In-line → Outperform
Sep-04-18 Initiated Citigroup Buy
Aug-06-18 Downgrade Goldman Buy → Neutral
Jun-28-18 Initiated Raymond James Mkt Perform
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Madrigal Pharmaceuticals Inc Stock (MDGL) Latest News

pulisher
Feb 25, 2026

Why Madrigal Pharmaceuticals (MDGL) Is Down 9.7% After Rezdiffra’s Near US$1 Billion Debut Year - Yahoo Finance

Feb 25, 2026
pulisher
Feb 25, 2026

Exit Recap: Will Madrigal Pharmaceuticals Inc outperform during market ralliesEarnings Summary Report & Weekly Setup with High ROI Potential - baoquankhu1.vn

Feb 25, 2026
pulisher
Feb 25, 2026

Madrigal: The Easiest Money May Have Been Made (NASDAQ:MDGL) - Seeking Alpha

Feb 25, 2026
pulisher
Feb 24, 2026

Madrigal Pharmaceuticals Reports 2025 Financial Results - MyChesCo

Feb 24, 2026
pulisher
Feb 24, 2026

Madrigal Pharmaceuticals to Participate in the TD Cowen 46th Annual Health Care Conference - The Manila Times

Feb 24, 2026
pulisher
Feb 24, 2026

Madrigal Q4 earnings miss, MASH drug sales drive top line, stock down - MSN

Feb 24, 2026
pulisher
Feb 23, 2026

Madrigal Grants Inducement Awards to Five Employees - MyChesCo

Feb 23, 2026
pulisher
Feb 23, 2026

Madrigal (MDGL) Q4 2025 Earnings Call Transcript - The Globe and Mail

Feb 23, 2026
pulisher
Feb 23, 2026

A Look At Madrigal Pharmaceuticals (MDGL) Valuation After Rezdiffra’s First Full Year Near US$1b In Sales - simplywall.st

Feb 23, 2026
pulisher
Feb 23, 2026

Madrigal Pharmaceuticals, Inc. (MDGL): Investor Outlook Reveals 53% Potential Upside In Biotechnology - DirectorsTalk Interviews

Feb 23, 2026
pulisher
Feb 23, 2026

Madrigal’s Rezdiffra Breakthrough Spurs MASH Pipeline Growth And Valuation Debate - Yahoo Finance

Feb 23, 2026
pulisher
Feb 23, 2026

MASH Drugs Market to hit US$ 929.05 Million by 2033 | North America - openPR.com

Feb 23, 2026
pulisher
Feb 20, 2026

Madrigal Pharmaceuticals Stock: A Deep Dive Into Analyst Perspectives (5 Ratings) - Benzinga

Feb 20, 2026
pulisher
Feb 20, 2026

Madrigal Q4 Earnings Miss, MASH Drug Sales Drive Top Line, Stock Down - Bitget

Feb 20, 2026
pulisher
Feb 20, 2026

Is now the right time to enter Madrigal Pharmaceuticals Inc.July 2025 Opening Moves & Safe Entry Momentum Tips - mfd.ru

Feb 20, 2026
pulisher
Feb 20, 2026

MDGL: B of A Securities Maintains Neutral Rating, Lowers Price T - GuruFocus

Feb 20, 2026
pulisher
Feb 20, 2026

Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) Q4 2025 Earnings Call Transcript - Insider Monkey

Feb 20, 2026
pulisher
Feb 20, 2026

Madrigal inks licensing deal with China’s Suzhou Ribo for MASH drugs - MSN

Feb 20, 2026
pulisher
Feb 20, 2026

Decoding Madrigal Pharmaceuticals Inc (MDGL): A Strategic SWOT I - GuruFocus

Feb 20, 2026
pulisher
Feb 19, 2026

Madrigal Pharma earnings missed by $1.97, revenue topped estimates - Investing.com Canada

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Eyes MASH Future As Rezdiffra Nears Blockbuster Revenue - Citeline News & Insights

Feb 19, 2026
pulisher
Feb 19, 2026

Earnings call transcript: Madrigal Pharmaceuticals Q4 2025 misses EPS, stock dips - Investing.com India

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals Inc (MDGL) Q4 2025 Earnings Call Highlights: Record Sales and ... By GuruFocus - Investing.com Canada

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals, Inc. reports strong Rezdiffra sales growth in Q4 2025; first full year of launch approaches $1 billion in net sales - AlphaStreet News

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals, Inc. Q4 2025 Earnings Call Summary - Yahoo Finance

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals (MDGL) Reports Strong Q4 2025 Performan - GuruFocus

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals Q4 2025 Earnings Call Transcript - MarketBeat

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals Q4 Earnings Call Highlights - Yahoo Finance

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals Stock Drops 11% Despite Reporting Narrower Loss In Q4 - Nasdaq

Feb 19, 2026
pulisher
Feb 19, 2026

Sector Update: Health Care Stocks Flat to Lower Pre-Bell Thursday - marketscreener.com

Feb 19, 2026
pulisher
Feb 19, 2026

MADRIGAL PHARMACEUTICALS, INC. SEC 10-K Report - TradingView

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals (MDGL) Faces Mixed Q4 2025 Results - GuruFocus

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal (MDGL) Reports Q4 Loss, Beats Revenue Estimates - Yahoo Finance Singapore

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal (MDGL) Surpasses Q4 Revenue Expectations, Eyes Future G - GuruFocus

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal down after wider-than-expected Q4 loss - Seeking Alpha

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal: Q4 Earnings Snapshot - kens5.com

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharma shares fall over 5% as Q4 earnings miss overshadows revenue beat - Investing.com Nigeria

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharma shares fall over 5% as Q4 earnings miss overshadows revenue beat By Investing.com - Investing.com Canada

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals Reports Fourth-Quarter and Full-Year 2025 Financial Results - Bitget

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals Q4 Loss Narrows, Revenue Rises - marketscreener.com

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal: Q4 Financial Results Overview - Bitget

Feb 19, 2026
pulisher
Feb 19, 2026

MADRIGAL PHARMACEUTICALS ($MDGL) Releases Q4 2025 Earnings - Quiver Quantitative

Feb 19, 2026
pulisher
Feb 19, 2026

Earnings Flash (MDGL) Madrigal Pharmaceuticals Posts Q4 Net Loss $2.57 a Share, vs. FactSet Est of $0.90 Loss - marketscreener.com

Feb 19, 2026
pulisher
Feb 19, 2026

Madrigal Pharmaceuticals Q4 revenue rises sharply on Rezdiffra sales - TradingView

Feb 19, 2026
pulisher
Feb 19, 2026

MDGL: Rezdiffra net sales neared $1B in 2025, with pipeline growth and improved financial position - TradingView

Feb 19, 2026
pulisher
Feb 18, 2026

Madrigal earnings up next: Can Rezdiffra momentum offset losses? - Investing.com India

Feb 18, 2026
pulisher
Feb 18, 2026

Earnings Preview For Madrigal Pharmaceuticals - Benzinga

Feb 18, 2026
pulisher
Feb 18, 2026

Madrigal’s $50M Pfizer deal sparks a new MASH drug power play - MSN

Feb 18, 2026
pulisher
Feb 17, 2026

John Paulson's Strategic Moves: Madrigal Pharmaceuticals Inc. Sees a -3.09% Impact - GuruFocus

Feb 17, 2026
pulisher
Feb 17, 2026

Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4) - The Manila Times

Feb 17, 2026

Madrigal Pharmaceuticals Inc Stock (MDGL) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$103.24
price down icon 1.52%
$51.37
price up icon 1.68%
$28.66
price up icon 1.42%
$109.84
price down icon 0.94%
$148.61
price down icon 6.31%
biotechnology ONC
$352.23
price down icon 4.54%
Cap:     |  Volume (24h):