1.61
price down icon2.42%   -0.04
after-market After Hours: 1.61
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Lexicon Pharmaceuticals Inc stock is traded at $1.61, with a volume of 2.05M. It is down -2.42% in the last 24 hours and down -19.50% over the past month. Lexicon Pharmaceuticals Inc is a biopharmaceutical company. It is engaged in the discovery, development, and commercialization of pharmaceutical products for the treatment of human diseases. Some of its drug candidates are LX9211, an orally-delivered small molecule drug candidate, and LX9851, an orally-delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic.
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Previous Close:
$1.65
Open:
$1.65
24h Volume:
2.05M
Relative Volume:
0.96
Market Cap:
$716.38M
Revenue:
$69.64M
Net Income/Loss:
$-26.09M
P/E Ratio:
-22.52
EPS:
-0.0715
Net Cash Flow:
$-38.80M
1W Performance:
-8.00%
1M Performance:
-19.50%
6M Performance:
-5.85%
1Y Performance:
+11.81%
1-Day Range:
Value
$1.59
$1.655
1-Week Range:
Value
$1.59
$1.78
52-Week Range:
Value
$1.10
$2.68

Lexicon Pharmaceuticals Inc Stock (LXRX) Company Profile

Name
Name
Lexicon Pharmaceuticals Inc
Name
Phone
(281) 863-3000
Name
Address
2445 TECHNOLOGY FOREST BLVD., THE WOODLANDS
Name
Employee
81
Name
Twitter
@LexPharma
Name
Next Earnings Date
2026-11-05
Name
Latest SEC Filings
Name
LXRX's Discussions on Twitter

Compare LXRX vs VRTX, MRNA, REGN, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
LXRX icon
LXRX
Lexicon Pharmaceuticals Inc
1.61 716.38M 69.64M -26.09M -38.80M -0.0715
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
485.22 122.98B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
216.25 86.33B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
753.12 77.54B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
802.64 50.47B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
188.44 40.39B 742.00K -1.37B -1.07B -7.0731

Lexicon Pharmaceuticals Inc Stock (LXRX) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-28-26 Initiated Cantor Fitzgerald Overweight
Mar-05-25 Downgrade Leerink Partners Outperform → Market Perform
Jun-17-24 Initiated H.C. Wainwright Buy
Apr-30-24 Initiated Leerink Partners Outperform
Mar-07-23 Initiated Jefferies Hold
Aug-12-22 Initiated Piper Sandler Overweight
Jan-29-21 Upgrade JP Morgan Underweight → Neutral
Jan-29-21 Downgrade Wedbush Outperform → Neutral
Dec-08-20 Upgrade Citigroup Neutral → Buy
Nov-18-20 Upgrade Gabelli & Co Hold → Buy
Dec-11-19 Downgrade Gabelli & Co Buy → Hold
Nov-08-19 Downgrade Citigroup Buy → Neutral
Sep-11-19 Upgrade Gabelli & Co Hold → Buy
Jul-29-19 Downgrade Stifel Buy → Hold
Mar-25-19 Upgrade Gabelli & Co Sell → Hold
Jul-31-18 Reiterated Stifel Buy
Feb-23-18 Downgrade Needham Buy → Hold
Feb-14-18 Downgrade JP Morgan Neutral → Underweight
Mar-01-17 Reiterated H.C. Wainwright Buy
Mar-01-17 Reiterated Wedbush Outperform
Oct-07-16 Initiated H.C. Wainwright Buy
Aug-05-16 Reiterated Wedbush Outperform
Aug-02-16 Initiated Citigroup Buy
Mar-02-16 Reiterated Wedbush Outperform
Nov-09-15 Reiterated Wedbush Outperform
Sep-28-15 Upgrade Gabelli & Co Sell → Hold
Sep-18-15 Downgrade Gabelli & Co Hold → Sell
Aug-10-15 Downgrade JP Morgan Overweight → Neutral
View All

Lexicon Pharmaceuticals Inc Stock (LXRX) Latest News

pulisher
Oct 09, 2026

Lexicon Pharmaceuticals (LXRX) Short Interest & Short Float | Updated Oct 2026 $LXRX - MarketBeat

Oct 09, 2026
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Oct 06, 2026

Lexicon Pharmaceuticals stock faces a Q2 loss as trials advance - AD HOC NEWS

Oct 06, 2026
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Oct 06, 2026

Lexicon Pharmaceuticals, Inc.Common Stock (Nasdaq:LXRX) Stock Quote - FinancialContent

Oct 06, 2026
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Oct 06, 2026

Lexicon Pharmaceuticals Q2 2026 Earnings Call: Complete Transcript - Benzinga

Oct 06, 2026
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Oct 06, 2026

Lexicon Pharmaceuticals Q2 2026 Earnings Call: Complete Transcript - Benzinga

Oct 06, 2026
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Oct 04, 2026

Fair value rises to USD 4.55 for Lexicon Pharmaceuticals stock - AD HOC NEWS

Oct 04, 2026
pulisher
Oct 03, 2026

Lexicon Pharmaceuticals, Inc. (LXRX) Stock Price, News, Quote & History - Yahoo! Finance Canada

Oct 03, 2026
pulisher
Oct 02, 2026

Lexicon Pharmaceuticals (LXRX) Stock Fair Value Rises After SONATA HCM Trial Progress - Yahoo Finance

Oct 02, 2026
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Oct 01, 2026

Cantor Fitzgerald targets Lexicon Pharmaceuticals stock at USD 8.00 - AD HOC NEWS

Oct 01, 2026
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Sep 30, 2026

Lexicon Pharmaceuticals upgraded to Buy with ke... - Pluang

Sep 30, 2026
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Sep 30, 2026

Lexicon Pharmaceuticals: Upgrading On Sotagliflozin HCM Data In Q1 '27 And More - Seeking Alpha

Sep 30, 2026
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Sep 28, 2026

Analyst Bullish on Lexicon Pharmaceuticals' Prospects - Intellectia AI

Sep 28, 2026
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Sep 28, 2026

Why Lexicon Pharmaceuticals Stock Popped by Almost 6% Today - Yahoo Finance

Sep 28, 2026
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Sep 28, 2026

Why Lexicon Pharmaceuticals Stock Popped by Almost 6% Today - The Motley Fool

Sep 28, 2026
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Sep 28, 2026

Cantor Fitzgerald Initiates Overweight on Lexicon Pharmaceuticals (LXRX) Ahead of Phase 3 Inpefa Data - GuruFocus

Sep 28, 2026
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Sep 28, 2026

Lexicon a new overweight at Cantor on optimism for Inpefa in cardiomyopathy - Seeking Alpha

Sep 28, 2026
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Sep 28, 2026

Why is Lexicon Pharmaceuticals stock surging today? By Investing.com - Investing.com Canada

Sep 28, 2026
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Sep 28, 2026

Lexicon Pharmaceuticals surges as Cantor Fitzgerald sees unencumbered path in HCM - Investing.com

Sep 28, 2026
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Sep 28, 2026

This Lexicon Pharmaceuticals Analyst Begins Coverage On A Bullish Note; Here Are Top 5 Initiations For Monday - Benzinga

Sep 28, 2026
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Sep 28, 2026

LXRX Initiated Coverage by Cantor Fitzgerald -- Rating Set at Ov - GuruFocus

Sep 28, 2026
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Sep 28, 2026

Cantor Fitzgerald initiates coverage of Lexicon Pharmaceuticals with Overweight rating, $8 price target - TradingView

Sep 28, 2026
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Sep 28, 2026

Lexicon Pharmaceuticals (NasdaqCM:LXRX) Stock Forecast & Analyst Predictions - Simply Wall Street

Sep 28, 2026
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Sep 28, 2026

Lexicon Pharmaceuticals Shares Rise After Cantor Fitzgerald Initiates With Overweight Rating - Yahoo Finance

Sep 28, 2026
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Sep 28, 2026

Lexicon Pharmaceuticals surges as Cantor Fitzgerald sees unencumbered path in HCM - Yahoo Finance

Sep 28, 2026
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Sep 23, 2026

Lexicon Pharmaceuticals stock trades near its yearly low - AD HOC NEWS

Sep 23, 2026
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Sep 20, 2026

Lexicon Completes SONATA-HCM Enrollment, Eyes 2027 Sotagliflozin Data - finance.yahoo.com

Sep 20, 2026
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Sep 10, 2026

Lexicon Pharmaceuticals at cantorfitzgerald healthcare conference: focus sharpens - Investing.com

Sep 10, 2026
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Sep 10, 2026

Lexicon Pharmaceuticals at cantorfitzgerald healthcare conference: focus sharpens By Investing.com - Investing.com Canada

Sep 10, 2026
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Sep 09, 2026

Lexicon Pharmaceuticals at Citi summit: hcm data, t1d reset By Investing.com - Investing.com Canada

Sep 09, 2026
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Sep 09, 2026

Lexicon Pharmaceuticals at Citi summit: hcm data, t1d reset By Investing.com - Investing.com UK

Sep 09, 2026
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Sep 09, 2026

Heart Failure Trial Data Might Change The Case For Investing In Lexicon Pharmaceuticals (LXRX) - webull.com

Sep 09, 2026
pulisher
Sep 08, 2026

Heart Failure Trial Data Might Change The Case For Investing In Lexicon Pharmaceuticals (LXRX) - simplywall.st

Sep 08, 2026
pulisher
Sep 05, 2026

Lexicon Pharmaceuticals Stock Price Forecast. Should You Buy LXRX? - StockInvest.us

Sep 05, 2026
pulisher
Sep 04, 2026

Here's Why You Should Add LXRX Stock to Your Portfolio Now - Eastern Progress

Sep 04, 2026
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Sep 04, 2026

Lexicon Pharmaceuticals Inc (LXRX) Valuation: PE, PB & Fair Value Analysis - TradingKey

Sep 04, 2026
pulisher
Sep 01, 2026

Three New York investor conferences will hear from Lexicon - Stock Titan

Sep 01, 2026
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Sep 01, 2026

Lexicon Pharmaceuticals to Participate at Three Upcoming Investor Conferences - finance.yahoo.com

Sep 01, 2026
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Aug 31, 2026

Lexicon Pharmaceuticals (LXRX) Posts Positive Heart Failure Tria - GuruFocus

Aug 31, 2026
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Aug 31, 2026

Lexicon Announces New Post Hoc SOLOIST-WHF Analysis Demonstrating Consistent Sotagliflozin Results Across Baseline Blood Pressure Levels in Patients with Recent Worsening Heart Failure - Yahoo Finance

Aug 31, 2026
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Aug 31, 2026

Sotagliflozin Linked to Fewer Heart-Failure Events in Patients With BP as Low as 100 - Stock Titan

Aug 31, 2026
pulisher
Aug 27, 2026

Lexicon Pharmaceuticals Inc. (LXRX) Key Financial Ratios – Valuation, Profitability & More - Value Research

Aug 27, 2026
pulisher
Aug 24, 2026

Lexicon (LXRX) Results at a Glance: EPS Misses Its Estimate in the Reported Period; Post-Earnings: The Market Price Advances 0.87% at the CloseNegative Surprise Momentum - vinanet.vn

Aug 24, 2026
pulisher
Aug 24, 2026

Lexicon Pharma Earns $10 Million Milestone Payment from Novo Nordisk - marketscreener.com

Aug 24, 2026
pulisher
Aug 24, 2026

Lexicon Pharmaceuticals (LXRX) Advances Obesity Drug Trial, Faces Valuation Challenges - GuruFocus

Aug 24, 2026
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Aug 24, 2026

Lexicon Pharmaceuticals Gets $10 Million Novo Nordisk Milestone Payment for LX9851 - marketscreener.com

Aug 24, 2026
pulisher
Aug 24, 2026

LXRX Stock Edges Higher On $10M Payout From Novo Nordisk — Retail Traders Highlight More Cash Milestones On The Horizon - Yahoo Finance

Aug 24, 2026
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Aug 24, 2026

Lexicon Pharmaceuticals Earns Third $10 Million Milestone Payment from Novo Nordisk Following Achievement of Key Phase 1 Development Milestone for LX9851 - finance.yahoo.com

Aug 24, 2026
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Aug 20, 2026

The Bull Case For Lexicon Pharmaceuticals (LXRX) Could Change Following Steep Q2 Revenue Drop And Loss Shift - simplywall.st

Aug 20, 2026
pulisher
Aug 20, 2026

The Bull Case For Lexicon Pharmaceuticals (LXRX) Could Change Following Steep Q2 Revenue Drop And Loss Shift - simplywall.st

Aug 20, 2026
pulisher
Aug 19, 2026

Lexicon (LXRX) Levels: Slides 0.41% to $2.41 in the Current Update; Technical Setup - vinanet.vn

Aug 19, 2026

Lexicon Pharmaceuticals Inc Stock (LXRX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Lexicon Pharmaceuticals Inc Stock (LXRX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Sullivan Diane E.
Director
Jun 03 '26
Option Exercise
0.00
89,312
0
126,122
SOBECKI CHRISTOPHER J
Director
Jun 03 '26
Option Exercise
0.00
89,312
0
293,177
Cheung Ivan
Director
Jun 03 '26
Option Exercise
0.00
89,312
0
89,312
BARKER SAM L
Director
Jun 03 '26
Option Exercise
0.00
89,312
0
213,771
Amouyal Philippe
Director
Jun 03 '26
Option Exercise
0.00
89,312
0
374,486
DEBBANE RAYMOND
Director
Jun 03 '26
Option Exercise
0.00
89,312
0
1,995,498
Artal Participations S.a r.l.
Director
Apr 30 '26
Option Exercise
0.00
20,421,735
0
175,156,062
DEBBANE RAYMOND
Director
Feb 25 '26
Buy
1.49
2,000
2,980
1,906,186
DEBBANE RAYMOND
Director
Feb 23 '26
Buy
1.47
100,000
147,000
1,904,186
DEBBANE RAYMOND
Director
Feb 20 '26
Buy
1.48
100,000
147,790
1,804,186
$8.69
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Cap:     |  Volume (24h):