12.48
price down icon0.79%   -0.10
after-market After Hours: 12.70 0.22 +1.76%
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Crescent Biopharma Inc stock is traded at $12.48, with a volume of 294.95K. It is down -0.79% in the last 24 hours and down -33.62% over the past month. Crescent Biopharma Inc is a biopharmaceutical company developing novel therapeutics to treat solid tumors, led by CR-001, a proprietary anti-PD-1/anti-VEGF bispecific antibody. Crescent's pipeline product CR-001 has the potential to deliver improved clinical efficacy and safety over pembrolizumab. CR-001 is a new molecular entity designed to replicate the functional properties of ivonescimab, a cooperative bispecific anti-PD-1/anti-VEGF antibody in development by Akeso Biopharma and Summit Therapeutics that delivered improved efficacy in a head-to-head Phase 3 clinical trial versus Keytruda in non-small cell lung cancer. The company focuses on advancing its second and third programs, CR-002 and CR-003, which are antibody drug conjugates (ADCs) against validated oncology targets.
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Previous Close:
$12.58
Open:
$12.62
24h Volume:
294.95K
Relative Volume:
0.82
Market Cap:
$463.59M
Revenue:
$11.88M
Net Income/Loss:
$-162.08M
P/E Ratio:
-0.9997
EPS:
-12.484
Net Cash Flow:
$-156.43M
1W Performance:
-11.61%
1M Performance:
-33.62%
6M Performance:
-37.44%
1Y Performance:
+10.54%
1-Day Range:
Value
$12.31
$13.19
1-Week Range:
Value
$12.18
$15.28
52-Week Range:
Value
$8.72
$27.41

Crescent Biopharma Inc Stock (CBIO) Company Profile

Name
Name
Crescent Biopharma Inc
Name
Phone
617-430-5595
Name
Address
300 FIFTH AVENUE, WALTHAM, CA
Name
Employee
44
Name
Twitter
@catalystbio
Name
Next Earnings Date
2026-11-05
Name
Latest SEC Filings
Name
CBIO's Discussions on Twitter

Compare CBIO vs VRTX, MRNA, REGN, ARGX, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
CBIO icon
CBIO
Crescent Biopharma Inc
12.48 463.59M 11.88M -162.08M -156.43M -12.48
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
508.75 128.95B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
236.50 94.42B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
796.34 81.99B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
846.27 53.22B 4.16B 1.29B 734.26M 19.58
ONC icon
ONC
Beone Medicines Ltd Adr
374.08 42.32B 5.76B 514.49M 1.10B 4.4813

Crescent Biopharma Inc Stock (CBIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Oct-06-26 Upgrade H.C. Wainwright Neutral → Buy
Jun-01-26 Downgrade H.C. Wainwright Buy → Neutral
Jan-28-26 Initiated Piper Sandler Overweight
Jan-21-26 Initiated Guggenheim Buy
Aug-25-25 Initiated Jefferies Buy
Aug-11-25 Initiated H.C. Wainwright Buy
Jul-14-25 Initiated Wedbush Outperform
Jun-25-25 Initiated Stifel Buy
Mar-21-25 Initiated Cantor Fitzgerald Overweight
Mar-11-25 Initiated Noble Capital Markets Outperform
Jul-26-24 Downgrade TD Cowen Buy → Hold
Dec-22-23 Initiated CapitalOne Overweight
Nov-12-21 Upgrade Jefferies Hold → Buy
Apr-29-21 Resumed Stephens Overweight
Feb-10-21 Initiated Piper Sandler Overweight
May-21-20 Initiated Raymond James Outperform
Nov-14-19 Initiated ROTH Capital Buy
Aug-05-19 Downgrade Jefferies Buy → Hold
Aug-05-19 Downgrade Piper Jaffray Overweight → Neutral
Aug-05-19 Downgrade SunTrust Buy → Hold
Apr-12-19 Initiated Piper Jaffray Overweight
Jan-04-19 Initiated Oppenheimer Outperform
Dec-18-18 Initiated H.C. Wainwright Buy
Feb-12-18 Reiterated B. Riley FBR, Inc. Buy
Feb-09-18 Reiterated Chardan Capital Markets Buy
Dec-08-17 Initiated B. Riley FBR, Inc. Buy
Jun-12-17 Initiated Chardan Capital Markets Buy
Jun-06-17 Initiated Ladenburg Thalmann Buy
Jul-26-16 Initiated SunTrust Buy
Jun-30-16 Initiated Rodman & Renshaw Buy
Mar-17-15 Reiterated Stifel Buy
View All

Crescent Biopharma Inc Stock (CBIO) Latest News

pulisher
Oct 05, 2026

Crescent Biopharma Announces FDA Clearance of IND for CR-002 and Plans Global Phase 1/2 APOLLO Trial in Advanced Solid Tumors - Quiver Quantitative

Oct 05, 2026
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Sep 25, 2026

Crescent Biopharma Announces Grants of Inducement Awards - Yahoo Finance

Sep 25, 2026
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Sep 21, 2026

Crescent Biopharma (Nasdaq:CBIO)Stock Analysis - Simply Wall Street

Sep 21, 2026
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Sep 17, 2026

BetterLife Pharma Raises $100 Million in a Public Offering of Shares and Warrants - Yahoo Finance

Sep 17, 2026
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Sep 16, 2026

Planned 804-share sale at Crescent Biopharma (Nasdaq: CBIO) - Stock Titan

Sep 16, 2026
pulisher
Sep 12, 2026

Certain Warrants of Crescent Biopharma, Inc. are subject to a Lock-Up Agreement Ending on 13-SEP-2026. - marketscreener.com

Sep 12, 2026
pulisher
Sep 12, 2026

Certain Options of Crescent Biopharma, Inc. are subject to a Lock-Up Agreement Ending on 13-SEP-2026. - marketscreener.com

Sep 12, 2026
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Sep 10, 2026

CBIO: Major clinical milestones and global expansion set for 2027, with key data and partnerships advancing - TradingView

Sep 10, 2026
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Sep 10, 2026

Crescent Biopharma at Cantor conference: global trial push By Investing.com - Investing.com Canada

Sep 10, 2026
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Sep 10, 2026

Crescent Biopharma at Cantor conference: global trial push - Investing.com India

Sep 10, 2026
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Sep 10, 2026

Crescent Biopharma at Cantor conference: global trial push - investing.com

Sep 10, 2026
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Sep 09, 2026

Two employees receive options tied to 58,650 Crescent Biopharma shares - Stock Titan

Sep 09, 2026
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Sep 09, 2026

Crescent Biopharma Announces Grants of Inducement Awards - Yahoo Finance

Sep 09, 2026
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Sep 03, 2026

Crescent Biopharma (CBIO) Surges 8.9% to $20.20 as Biotech Momentum BuildsIV Contraction - vinanet.vn

Sep 03, 2026
pulisher
Sep 03, 2026

Crescent Biopharma (CBIO) Surges 8.9% to $20.20 as Biotech Momentum BuildsTRIN Signal - siam.in

Sep 03, 2026
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Sep 03, 2026

Crescent Biopharma (CBIO) Surges 8.9% to $20.20 as Biotech Momentum BuildsStatistical Arbitrage - dars.gov.et

Sep 03, 2026
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Sep 03, 2026

Crescent Biopharma Announces September 2026 Investor Conference Presentations - quiverquant.com

Sep 03, 2026
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Sep 03, 2026

Crescent Biopharma to Present at September Investor Conferences - GlobeNewswire

Sep 03, 2026
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Sep 03, 2026

Crescent Biopharma to Present at September Investor Conferences - Yahoo Finance

Sep 03, 2026
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Sep 03, 2026

Crescent Capital (CCAP) holder sells at about $10.50 under trading plan - Stock Titan

Sep 03, 2026
pulisher
Aug 21, 2026

Crescent Biopharma, Inc. (NASDAQ:CBIO) Receives Consensus Recommendation of "Moderate Buy" from Analysts - MarketBeat

Aug 21, 2026
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Aug 20, 2026

Balyasny Asset Management L.P. Expands Stake in Crescent Biophar - GuruFocus

Aug 20, 2026
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Aug 17, 2026

Crescent Biopharma (NASDAQ:CBIO) Stock Price Up 4.9%Should You Buy? - MarketBeat

Aug 17, 2026
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Aug 14, 2026

Balyasny Asset Management (CBIO) discloses 6.03% Crescent Biopharma ownership - Stock Titan

Aug 14, 2026
pulisher
Aug 12, 2026

Crescent Biopharma (NASDAQ:CBIO) Shares Gap DownShould You Sell? - MarketBeat

Aug 12, 2026
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Aug 11, 2026

Crescent Biopharma (CBIO) Shares Dip 2.86% as Stock Approaches Key $16 Support LevelDay Trade Opportunities - vinanet.vn

Aug 11, 2026
pulisher
Aug 08, 2026

CBIO Q2 2026 Earnings: Narrower-Than-Expected Loss Buoys SharesRevenue Miss Report - vinanet.vn

Aug 08, 2026
pulisher
Aug 06, 2026

Crescent Biopharma Ord Shs (CBIO) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Aug 06, 2026
pulisher
Aug 05, 2026

Q3 EPS Forecast for Crescent Biopharma Lowered by Analyst - marketbeat.com

Aug 05, 2026
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Aug 04, 2026

Analysts Offer Insights on Healthcare Companies: Dyne Therapeutics (DYN) and Crescent Biopharma (CBIO) - The Globe and Mail

Aug 04, 2026
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Aug 03, 2026

Crescent Biopharma Announces Grants of Inducement Awards - The Manila Times

Aug 03, 2026
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Aug 03, 2026

Crescent Biopharma Announces Grants of Inducement Awards - GlobeNewswire

Aug 03, 2026
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Aug 03, 2026

CRESCENT BIOPHARMA, INC. SEC Filing (Aug 3, 2026) - Stock Titan

Aug 03, 2026
pulisher
Aug 02, 2026

Perceptive Advisors LLC Lowers Stake in Crescent Biopharma, Inc. $CBIO - MarketBeat

Aug 02, 2026
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Aug 01, 2026

Crescent Biopharma (CBIO) Gets a Buy from Wedbush - The Globe and Mail

Aug 01, 2026
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Jul 30, 2026

Crescent Biopharma Announces Q2 2026 Financial Results and Operational Update - Kalkine Media

Jul 30, 2026
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Jul 30, 2026

Crescent Biopharma Reports Q2 2026 Results and Advances Clinical Development of CR-001, CR-002 and CR-003 - Quiver Quantitative

Jul 30, 2026
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Jul 30, 2026

Crescent Biopharma: Q2 Earnings Snapshot - KING5.com

Jul 30, 2026
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Jul 30, 2026

Crescent Biopharma posts $24.8 million Q2 net loss - Quiver Quantitative

Jul 30, 2026
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Jul 30, 2026

Crescent Biopharma Reports Second Quarter 2026 Financial Results and Recent Business Highlights - GlobeNewswire

Jul 30, 2026
pulisher
Jul 30, 2026

Crescent Biopharma posts $24.8 million Q2 net loss - quiverquant.com

Jul 30, 2026
pulisher
Jul 28, 2026

CBIO Q1 2026 Earnings: EPS Beat Despite Pre-Revenue Status; Stock DeclinesEPS Guidance Update - vinanet.vn

Jul 28, 2026
pulisher
Jul 27, 2026

Crescent Biopharma Ord Shs (CBIO) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jul 27, 2026
pulisher
Jul 27, 2026

Crescent Biopharma Ord Shs (CBIO) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jul 27, 2026
pulisher
Jul 27, 2026

Crescent Biopharma Market Sentiment - Benzinga España

Jul 27, 2026
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Jul 27, 2026

Crescent Biopharma, Inc. (NASDAQ:CBIO) Given Consensus Rating of "Moderate Buy" by Analysts - MarketBeat

Jul 27, 2026
pulisher
Jul 27, 2026

Crescent Biopharma Ord Shs (CBIO) Institutional Confidence - TradingKey

Jul 27, 2026
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Jul 26, 2026

CBIO Q1 2026 Earnings: Narrower Loss Surprises Analysts as Cash Management ImprovesEarnings Quality Score - vinanet.vn

Jul 26, 2026
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Jul 25, 2026

CBIO|Crescent Biopharma Ord Shs|Price:16.300|Chg%:-0.730 - TradingKey

Jul 25, 2026
pulisher
Jul 24, 2026

Crescent Biopharma (CBIO) Shares Dip 4.3% as Stock Pulls Back Toward Key SupportDefined Outcome ETF - dars.gov.et

Jul 24, 2026

Crescent Biopharma Inc Stock (CBIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Crescent Biopharma Inc Stock (CBIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Joshua T Brumm
Officer
Sep 18 '26
Proposed Sale
17.18
9,013
154,843
0
Jonathan McNeill
Officer
Sep 18 '26
Proposed Sale
17.18
4,415
75,850
0
McNeill Jonathan
President and COO
Sep 18 '26
Sale
16.71
3,839
64,150
134,588
Brumm Joshua T
Chief Executive Officer
Sep 18 '26
Sale
16.71
7,837
130,956
271,765
Brumm Joshua T
Chief Executive Officer
Sep 16 '26
Sale
17.90
1,610
28,819
279,602
McNeill Jonathan
President and COO
Sep 16 '26
Sale
17.90
731
13,085
138,427
Jonathan McNeill
Officer
Sep 16 '26
Proposed Sale
18.80
804
15,115
0
Joshua T Brumm
Officer
Sep 16 '26
Proposed Sale
18.80
1,771
33,295
0
Pinkas Jan
Chief Scientific Officer
Sep 16 '26
Sale
17.90
658
11,778
21,581
Im Ellie Eunkyung
Chief Medical Officer
Sep 16 '26
Sale
17.90
623
11,152
21,446
$7.50
price up icon 1.35%
$10.27
price up icon 0.39%
$5.74
price up icon 5.03%
$18.93
price up icon 5.17%
$10.91
price up icon 6.03%
WVE WVE
$3.19
price up icon 3.24%
Cap:     |  Volume (24h):