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Xilio Therapeutics Inc stock is traded at $8.35, with a volume of 22,654. It is up +1.21% in the last 24 hours and up +0.48% over the past month. Xilio Therapeutics Inc is a clinical-stage biotechnology company focused on discovering and developing masked immuno-oncology (I-O) therapies to improve outcomes for people living with cancer. Leveraging its clinically validated masking technology and capabilities, the company develops I-O therapies designed to selectively activate within the tumor microenvironment to achieve durable efficacy without the severe side effects associated with systemically active I-O agents. Its integrated biology and protein engineering approach enables the design and development of potent masked biologics that are activated by tumor-specific proteases.
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Previous Close:
$8.25
Open:
$8.41
24h Volume:
22,654
Relative Volume:
0.48
Market Cap:
$49.96M
Revenue:
$43.77M
Net Income/Loss:
$-35.04M
P/E Ratio:
-2.5676
EPS:
-3.2521
Net Cash Flow:
$-5.51M
1W Performance:
+2.08%
1M Performance:
+0.48%
6M Performance:
-20.49%
1Y Performance:
-32.52%
1-Day Range:
Value
$8.285
$8.5599
1-Week Range:
Value
$7.97
$8.6659
52-Week Range:
Value
$6.4652
$16.10

Xilio Therapeutics Inc Stock (XLO) Company Profile

Name
Name
Xilio Therapeutics Inc
Name
Phone
617-833-1027
Name
Address
828 WINTER STREET, WALTHAM
Name
Employee
76
Name
Twitter
Name
Next Earnings Date
2026-05-14
Name
Latest SEC Filings
Name
XLO's Discussions on Twitter

Compare XLO vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
XLO icon
XLO
Xilio Therapeutics Inc
8.35 49.36M 43.77M -35.04M -5.51M -3.2521
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
435.93 110.28B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
634.62 66.98B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
808.43 50.15B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
295.50 39.71B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
154.89 32.22B 742.00K -1.37B -1.07B -7.0731

Xilio Therapeutics Inc Stock (XLO) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-06-25 Initiated Leerink Partners Outperform
Dec-21-22 Initiated Chardan Capital Markets Buy
Jan-10-22 Initiated H.C. Wainwright Buy
Nov-16-21 Initiated Cowen Outperform
Nov-16-21 Initiated Guggenheim Buy
Nov-16-21 Initiated Morgan Stanley Overweight
Nov-16-21 Initiated Raymond James Outperform
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Xilio Therapeutics Inc Stock (XLO) Latest News

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May 22, 2026

XLO Q1 2026 Earnings: Narrower-Than-Expected Loss Lifts SharesCommunity Buy Signals - Newser

May 22, 2026
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May 21, 2026

Is Xilio Therapeutics (XLO) Still a Buy After +2.89% Rally? 2026-05-21Wyckoff Upthrust - Newser

May 21, 2026
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May 19, 2026

Xilio Therapeutics (XLO) Crushes Q1 2026 Estimates — EPS $-0.58 Tops ViewsHigh Interest Stocks - Newser

May 19, 2026
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May 18, 2026

Cancer Stocks That Are Advancing the Future of Oncology Care - TradingView

May 18, 2026
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May 17, 2026

Xilio Therapeutics, Inc. (XLO) reports Q1 loss, beats revenue estimates - MSN

May 17, 2026
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May 17, 2026

Xilio Therapeutics (XLO) Stock Analysis: Falls -5.11%, Watching $7.94 2026-05-17Technical Analysis - Newser

May 17, 2026
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May 16, 2026

Xilio Therapeutics (XLO) upgraded to buy: What does it mean for the stock? - MSN

May 16, 2026
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May 15, 2026

OrbiMed group discloses stakes in Xilio Therapeutics (NASDAQ: XLO), up to 9.99% - Stock Titan

May 15, 2026
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May 15, 2026

Bain Capital entities report 9.99% stake in Xilio Therapeutics (XLO) - Stock Titan

May 15, 2026
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May 15, 2026

Point72 (XLO) files 13G/A showing 0% stake in Xilio Therapeutics - Stock Titan

May 15, 2026
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May 15, 2026

Sirenia and Alex Silverstein report 9.9% stake in Xilio (NASDAQ: XLO) - Stock Titan

May 15, 2026
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May 14, 2026

TradingKey - TradingKey

May 14, 2026
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May 12, 2026

Xilio Therapeutics Releases Q1 2026 Financial Results - AlphaStreet

May 12, 2026
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May 12, 2026

Xilio Therapeutics, Inc. 2026 Q1 Quarterly Report: Financials, Risk Factors, and Business Overview - Minichart

May 12, 2026
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May 12, 2026

XLO Financials: Income Statement, Balance Sheet & Cash Flow - Stock Titan

May 12, 2026
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May 12, 2026

Sagimet Biosciences Releases Q1 2026 Financial Results - AlphaStreet

May 12, 2026
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May 12, 2026

Xilio Therapeutics, Inc. (XLO) Reports Q1 Loss, Beats Revenue Estimates - Yahoo Finance

May 12, 2026
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May 12, 2026

Xilio Therapeutics Reports Q1 2026 Financial Results, Advances Pipeline with XTX501 IND Filing and AbbVie Milestone Extension - Minichart

May 12, 2026
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May 12, 2026

Xilio Therapeutics Inc reports results for the quarter ended December 31Earnings Summary - TradingView

May 12, 2026
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May 12, 2026

According to documents submitted to the U.S. Securities and Exchange Commission (SEC), biotechnology company Xilio Therapeutics Inc. has entered into a common stock sales agreement with investment bank Leerink Partners LLC. - Bitget

May 12, 2026
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May 12, 2026

Xilio Therapeutics (NASDAQ: XLO) files $250M shelf, includes $17.22M ATM - Stock Titan

May 12, 2026
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May 12, 2026

Xilio Therapeutics, Inc. 1Q 2026: Revenue $12.6M, EPS $(0.58) — 10-Q Summary - TradingView

May 12, 2026
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May 12, 2026

Xilio Therapeutics (XLO) boosts Q1 2026 collaboration revenue and extends cash runway into 2028 - Stock Titan

May 12, 2026
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May 12, 2026

Xilio Therapeutics, Inc. Reports Earnings Results for the First Quarter Ended March 31, 2026 - marketscreener.com

May 12, 2026
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May 12, 2026

Xilio (Nasdaq: XLO) Q1 2026 loss narrows as cash runway extends to 2028 - Stock Titan

May 12, 2026
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May 12, 2026

Xilio Therapeutics Reports First Quarter 2026 Financial Results and Provides Pipeline and ... - Caledonian Record

May 12, 2026
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May 12, 2026

Xilio Therapeutics Reports First Quarter 2026 Financial Results and Provides Pipeline and Business Updates - GlobeNewswire

May 12, 2026
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May 11, 2026

XLO (Xilio Therapeutics) swings to profit, crushing estimates by 147.7 percent as stock gains.Expert Momentum Signals - newser.com

May 11, 2026
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May 11, 2026

Xilio Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)May 7, 2026 - marketscreener.com

May 11, 2026
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May 10, 2026

Number of shareholders of Xilio Therapeutics, Inc. – NASDAQ:XLO - TradingView

May 10, 2026
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May 08, 2026

XLO Xilio Therapeutics smashes Q4 earnings with 147.7% beat, 589.9% revenue surge, yet shares fall 1.14%.Expert Entry Points - newser.com

May 08, 2026
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May 07, 2026

Xilio Therapeutics Grants Options for 146,800 Shares to New Employees - geneonline.com

May 07, 2026
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May 07, 2026

New Xilio hire gets stock options for 1,982 shares at $8.32 - Stock Titan

May 07, 2026
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May 06, 2026

Actuate Therapeutics Adds Oncology Expert to Board Leadership - TipRanks

May 06, 2026
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May 06, 2026

Actuate Therapeutics appoints Martin Huber to board By Investing.com - Investing.com Australia

May 06, 2026
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May 06, 2026

Xilio Therapeutics Inc expected to post a loss of 66 cents a shareEarnings Preview - TradingView

May 06, 2026
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Apr 30, 2026

Net current asset value per share of Xilio Therapeutics, Inc. – NASDAQ:XLO - TradingView

Apr 30, 2026
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Apr 30, 2026

XLO Q1'26 Earnings: revenue estimate is 8.52M USD - TradingView

Apr 30, 2026
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Apr 30, 2026

Xilio Therapeutics (XLO) price target decreased by 28.57% to 20.40 - MSN

Apr 30, 2026
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Apr 28, 2026

[ARS] Xilio Therapeutics, Inc. SEC Filing - Stock Titan

Apr 28, 2026
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Apr 28, 2026

Xilio Therapeutics | ARS: Annual Report to Security Holders - Moomoo

Apr 28, 2026
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Apr 28, 2026

Stock plan change and virtual 2026 annual meeting at Xilio (XLO) - Stock Titan

Apr 28, 2026
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Apr 27, 2026

What failed trades Xilio Therapeutics (XLO)? (Slight Gain) 2026-04-27Market Expert Watchlist - Newser

Apr 27, 2026
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Apr 21, 2026

Xilio Therapeutics Announces 1-for-14 Reverse Stock Split - WFXG

Apr 21, 2026
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Apr 21, 2026

Xilio Therapeutics | 8-K: Current report - Moomoo

Apr 21, 2026
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Apr 18, 2026

Xilio Therapeutics (XLO) Stock: Growth Outlook (+2.63%) 2026-04-18Sector Analysis - Xã Vĩnh Công

Apr 18, 2026
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Apr 18, 2026

Xilio Therapeutics Announces New Preclinical Data at AACR Annual Meeting for XTX601, a Masked T Cell Engager Targeting CLDN18.2 - Sahm

Apr 18, 2026
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Apr 18, 2026

XLO: Xilio Therapeutics Presents Promising Preclinical Findings for XTX601 at AACR - GuruFocus

Apr 18, 2026
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Apr 17, 2026

Xilio announces new preclinical data for XTX601 at AACR - TipRanks

Apr 17, 2026
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Apr 17, 2026

Xilio Therapeutics appoints Cheryl Blanchard to board By Investing.com - Investing.com India

Apr 17, 2026

Xilio Therapeutics Inc Stock (XLO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$29.66
price down icon 0.98%
$92.25
price up icon 0.12%
$108.87
price up icon 2.48%
$53.86
price down icon 1.17%
ONC ONC
$302.44
price down icon 2.52%
$154.89
price up icon 2.20%
Cap:     |  Volume (24h):