68.99
price up icon7.78%   4.98
after-market After Hours: 70.20 1.21 +1.75%
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Spyre Therapeutics Inc Stock (SYRE) Price History

The historical daily chart and data for Spyre Therapeutics Inc stock (SYRE), show that the latest closing stock price as of April 15, 2026, is $68.99.
  • Spyre Therapeutics Inc all-time high stock price is $75.00, occurred on April 13, 2026.
  • The lowest Spyre Therapeutics Inc stock price recorded was $10.42 on November 28, 2023. Since then, Spyre Therapeutics Inc's stock price has risen over 562.09% to $68.99 now.
  • The 52-week high stock price for SYRE is $75.00, representing a 8.71% increase from the current share price, occurred on April 13, 2026.
  • The 52-week low stock price for SYRE is $12.25, indicating a -82.24% decrease from the current share price, occurred on April 17, 2025.
The table below shows more information about SYRE historical price data:
Date High Low High - Low Volume % Change
Apr 15, 2026 $69.45 $64.60 $4.85 4,198,453.0 +7.78%
Apr 14, 2026 $67.68 $60.75 $6.93 1,672,477.0 +1.17%
Apr 13, 2026 $75.00 $59.02 $15.98 5,356,921.0 +23.36%
Apr 10, 2026 $52.98 $50.85 $2.13 498,967.0 -0.93%
Apr 09, 2026 $52.77 $51.20 $1.57 585,552.0 -0.40%
Apr 08, 2026 $54.39 $50.39 $4.00 1,039,062.0 +1.52%
Apr 07, 2026 $51.26 $48.83 $2.43 799,418.0 +4.53%
Apr 06, 2026 $49.85 $46.79 $3.06 791,727.0 +2.94%
Apr 02, 2026 $48.40 $46.27 $2.13 438,009.0 -2.70%
Apr 01, 2026 $51.00 $48.64 $2.36 675,344.0 -3.05%
Mar 31, 2026 $51.06 $46.28 $4.78 1,016,004.0 +11.05%
Mar 30, 2026 $48.47 $44.80 $3.67 712,519.0 -3.99%
Mar 27, 2026 $47.95 $46.70 $1.25 832,414.0 -0.44%
Mar 26, 2026 $49.30 $45.23 $4.08 1,331,371.0 +4.03%
Mar 25, 2026 $45.79 $42.68 $3.11 666,398.0 +8.20%
Mar 24, 2026 $42.76 $40.91 $1.85 724,435.0 -1.26%
Mar 23, 2026 $44.08 $41.73 $2.35 779,408.0 +3.66%
Mar 20, 2026 $43.22 $41.16 $2.06 1,410,500.0 -2.51%
Mar 19, 2026 $43.22 $41.74 $1.48 622,276.0 -1.74%
Mar 18, 2026 $44.28 $42.36 $1.92 798,207.0 -2.03%
Mar 17, 2026 $45.39 $43.77 $1.62 838,641.0 -0.27%

Spyre Therapeutics Inc Stock (SYRE) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Spyre Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of SYRE shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Spyre Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Spyre Therapeutics Inc Stock (SYRE) Price History 2026

Month High Low High - Low Volume % Change
Apr, 2026 $75.00 $46.27 $28.73 20,254,383.0 +36.78%
Mar, 2026 $51.06 $38.36 $12.70 18,228,687.0 +17.28%
Feb, 2026 $45.76 $30.92 $14.84 14,598,463.0 +34.49%
Jan, 2026 $35.06 $28.00 $7.06 12,290,223.0 -2.38%

Spyre Therapeutics Inc Stock (SYRE) Price History 2025

Month High Low High - Low Volume % Change
Dec, 2025 $35.31 $28.16 $7.15 17,921,513.0 +6.27%
Nov, 2025 $30.21 $21.14 $9.07 11,809,120.0 +22.65%
Oct, 2025 $25.05 $15.86 $9.20 28,914,443.0 +45.94%
Sep, 2025 $17.58 $14.51 $3.07 13,700,922.0 +1.64%
Aug, 2025 $17.80 $14.72 $3.08 9,673,575.0 -2.83%
Jul, 2025 $18.30 $14.00 $4.30 12,397,594.0 +13.36%
Jun, 2025 $19.20 $13.93 $5.27 12,638,190.0 -2.03%
May, 2025 $15.77 $12.29 $3.48 10,197,865.0 +0.33%
Apr, 2025 $16.12 $10.91 $5.21 17,251,629.0 -5.61%
Mar, 2025 $21.03 $16.13 $4.90 13,287,855.0 -18.10%
Feb, 2025 $24.83 $18.26 $6.57 10,925,495.0 -14.31%
Jan, 2025 $26.01 $20.25 $5.76 11,749,605.0 -1.25%

Spyre Therapeutics Inc Stock (SYRE) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $29.06 $22.37 $6.69 9,847,302.0 -20.72%
Nov, 2024 $40.26 $25.74 $14.52 14,404,771.0 -12.60%
Oct, 2024 $36.60 $26.28 $10.32 8,567,734.0 +10.61%
Sep, 2024 $31.89 $26.52 $5.37 12,800,810.0 +2.30%
Aug, 2024 $29.00 $23.31 $5.69 8,943,039.0 +4.55%
Jul, 2024 $32.41 $23.00 $9.41 11,316,523.0 +16.97%
Jun, 2024 $38.90 $22.19 $16.71 20,949,923.0 -32.73%
May, 2024 $40.49 $31.39 $9.11 6,780,000.0 +5.81%
Apr, 2024 $40.84 $31.27 $9.57 6,849,784.0 -12.92%
Mar, 2024 $47.97 $28.48 $19.49 14,248,629.0 +38.23%
Feb, 2024 $28.80 $20.07 $8.73 9,579,014.0 +5.91%
Jan, 2024 $28.66 $18.54 $10.12 6,339,820.0 +20.40%
$54.26
price up icon 2.69%
$48.70
price down icon 0.25%
$99.47
price up icon 1.08%
$152.54
price up icon 3.76%
$146.74
price down icon 4.34%
ONC ONC
$319.94
price up icon 3.21%
Cap:     |  Volume (24h):