83.41
price down icon0.20%   -0.17
pre-market  Pre-market:  83.41  
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Spyre Therapeutics Inc Stock (SYRE) Price History

The historical daily chart and data for Spyre Therapeutics Inc stock (SYRE), show that the latest closing stock price as of June 16, 2026, is $83.41.
  • Spyre Therapeutics Inc all-time high stock price is $84.69, occurred on June 15, 2026.
  • The lowest Spyre Therapeutics Inc stock price recorded was $10.42 on November 28, 2023. Since then, Spyre Therapeutics Inc's stock price has risen over 700.48% to $83.41 now.
  • The 52-week high stock price for SYRE is $84.69, representing a 1.53% increase from the current share price, occurred on June 15, 2026.
  • The 52-week low stock price for SYRE is $13.93, indicating a -83.30% decrease from the current share price, occurred on June 17, 2025.
The table below shows more information about SYRE historical price data:
Date High Low High - Low Volume % Change
Jun 16, 2026 $84.92 $81.70 $3.22 1,337,022.0 -0.20%
Jun 15, 2026 $84.69 $80.79 $3.90 1,148,881.0 +3.45%
Jun 12, 2026 $84.43 $80.72 $3.71 958,594.0 +0.02%
Jun 11, 2026 $81.62 $75.35 $6.27 1,267,896.0 +7.58%
Jun 10, 2026 $79.52 $74.79 $4.73 981,263.0 -1.78%
Jun 09, 2026 $77.11 $70.89 $6.22 1,592,558.0 +6.17%
Jun 08, 2026 $76.31 $71.11 $5.20 1,035,946.0 -2.24%
Jun 05, 2026 $78.90 $73.06 $5.84 1,239,131.0 -6.15%
Jun 04, 2026 $79.54 $73.29 $6.25 963,136.0 +6.75%
Jun 03, 2026 $76.11 $69.81 $6.29 1,743,185.0 +6.30%
Jun 02, 2026 $70.50 $68.50 $2.00 814,331.0 -1.96%
Jun 01, 2026 $73.21 $68.85 $4.36 921,817.0 -4.03%
May 29, 2026 $74.36 $71.51 $2.85 1,113,419.0 +1.93%
May 28, 2026 $73.33 $71.08 $2.25 428,976.0 -0.55%
May 27, 2026 $74.35 $72.24 $2.11 557,955.0 -1.55%
May 26, 2026 $76.12 $72.11 $4.01 478,426.0 -0.54%
May 22, 2026 $75.63 $73.11 $2.52 574,913.0 -0.36%
May 21, 2026 $74.43 $70.18 $4.25 737,875.0 +3.34%
May 20, 2026 $72.47 $67.88 $4.59 1,088,200.0 +7.96%
May 19, 2026 $70.08 $64.67 $5.41 1,384,938.0 -4.94%

Spyre Therapeutics Inc Stock (SYRE) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Spyre Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of SYRE shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Spyre Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Spyre Therapeutics Inc Stock (SYRE) Price History 2026

Month High Low High - Low Volume % Change
Jun, 2026 $84.92 $68.50 $16.42 15,340,782.0 +13.48%
May, 2026 $78.80 $64.67 $14.13 20,278,975.0 -1.28%
Apr, 2026 $75.00 $46.27 $28.73 29,467,600.0 +47.60%
Mar, 2026 $51.06 $38.36 $12.70 18,228,687.0 +17.28%
Feb, 2026 $45.76 $30.92 $14.84 14,598,463.0 +34.49%
Jan, 2026 $35.06 $28.00 $7.06 12,290,223.0 -2.38%

Spyre Therapeutics Inc Stock (SYRE) Price History 2025

Month High Low High - Low Volume % Change
Dec, 2025 $35.31 $28.16 $7.15 17,921,513.0 +6.27%
Nov, 2025 $30.21 $21.14 $9.07 11,809,120.0 +22.65%
Oct, 2025 $25.05 $15.86 $9.20 28,914,443.0 +45.94%
Sep, 2025 $17.58 $14.51 $3.07 13,700,922.0 +1.64%
Aug, 2025 $17.80 $14.72 $3.08 9,673,575.0 -2.83%
Jul, 2025 $18.30 $14.00 $4.30 12,397,594.0 +13.36%
Jun, 2025 $19.20 $13.93 $5.27 12,638,190.0 -2.03%
May, 2025 $15.77 $12.29 $3.48 10,197,865.0 +0.33%
Apr, 2025 $16.12 $10.91 $5.21 17,251,629.0 -5.61%
Mar, 2025 $21.03 $16.13 $4.90 13,287,855.0 -18.10%
Feb, 2025 $24.83 $18.26 $6.57 10,925,495.0 -14.31%
Jan, 2025 $26.01 $20.25 $5.76 11,749,605.0 -1.25%

Spyre Therapeutics Inc Stock (SYRE) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $29.06 $22.37 $6.69 9,847,302.0 -20.72%
Nov, 2024 $40.26 $25.74 $14.52 14,404,771.0 -12.60%
Oct, 2024 $36.60 $26.28 $10.32 8,567,734.0 +10.61%
Sep, 2024 $31.89 $26.52 $5.37 12,800,810.0 +2.30%
Aug, 2024 $29.00 $23.31 $5.69 8,943,039.0 +4.55%
Jul, 2024 $32.41 $23.00 $9.41 11,316,523.0 +16.97%
Jun, 2024 $38.90 $22.19 $16.71 20,949,923.0 -32.73%
May, 2024 $40.49 $31.39 $9.11 6,780,000.0 +5.81%
Apr, 2024 $40.84 $31.27 $9.57 6,849,784.0 -12.92%
Mar, 2024 $47.97 $28.48 $19.49 14,248,629.0 +38.23%
Feb, 2024 $28.80 $20.07 $8.73 9,579,014.0 +5.91%
Jan, 2024 $28.66 $18.54 $10.12 6,339,820.0 +20.40%
$30.41
price up icon 1.27%
$55.40
price up icon 6.27%
$89.50
price down icon 1.43%
$54.21
price down icon 0.11%
ONC ONC
$263.92
price down icon 1.60%
$156.58
price down icon 2.17%
Cap:     |  Volume (24h):