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Spyre Therapeutics Inc stock is traded at $23.27, with a volume of 123.83K. It is down -2.52% in the last 24 hours and up +45.88% over the past month. Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.
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Previous Close:
$23.78
Open:
$23.29
24h Volume:
123.83K
Relative Volume:
0.15
Market Cap:
$1.40B
Revenue:
$688.00K
Net Income/Loss:
$-170.19M
P/E Ratio:
-7.6308
EPS:
-3.0495
Net Cash Flow:
$-154.68M
1W Performance:
-5.93%
1M Performance:
+45.88%
6M Performance:
+53.41%
1Y Performance:
-34.02%
1-Day Range:
Value
$23.01
$23.56
1-Week Range:
Value
$22.42
$25.00
52-Week Range:
Value
$10.91
$40.26

Spyre Therapeutics Inc Stock (SYRE) Company Profile

Name
Name
Spyre Therapeutics Inc
Name
Phone
(617) 651-5940
Name
Address
221 CRESCENT STREET, WALTHAM
Name
Employee
65
Name
Twitter
Name
Next Earnings Date
2024-11-07
Name
Latest SEC Filings
Name
SYRE's Discussions on Twitter

Compare SYRE with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SYRE
Spyre Therapeutics Inc
23.16 1.84B 688.00K -170.19M -154.68M -3.0495
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
426.52 109.22B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
635.93 67.50B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
427.26 57.35B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
841.69 50.87B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
184.96 39.72B 447.02M -1.18B -868.57M -6.1812

Spyre Therapeutics Inc Stock (SYRE) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-26-25 Initiated Deutsche Bank Buy
Apr-08-25 Initiated Leerink Partners Outperform
Mar-18-25 Initiated Wolfe Research Outperform
Sep-04-24 Initiated Wedbush Outperform
Jul-16-24 Initiated Evercore ISI Outperform
May-02-24 Initiated Robert W. Baird Outperform
Mar-01-24 Upgrade Wells Fargo Equal Weight → Overweight
Dec-20-23 Initiated BTIG Research Buy
Dec-11-23 Initiated Guggenheim Buy
Dec-11-23 Initiated Jefferies Buy
May-04-20 Initiated Piper Sandler Overweight
Mar-21-19 Initiated JP Morgan Overweight
Sep-04-18 Downgrade Wells Fargo Outperform → Market Perform
Apr-24-18 Initiated Evercore ISI Outperform
Mar-14-18 Reiterated Needham Buy
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Spyre Therapeutics Inc Stock (SYRE) Latest News

pulisher
07:16 AM

Will Spyre Therapeutics Inc. stock recover faster than peers2025 Retail Activity & Stock Market Timing Techniques - newser.com

07:16 AM
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06:01 AM

Will Spyre Therapeutics Inc. (3920) stock see insider accumulationEarnings Miss & AI Driven Stock Price Forecasts - newser.com

06:01 AM
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04:50 AM

Why Spyre Therapeutics Inc. stock is seen as undervaluedPortfolio Gains Summary & Breakout Confirmation Alerts - newser.com

04:50 AM
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04:50 AM

Can a trend reversal in Spyre Therapeutics Inc. lead to recoveryTrade Exit Report & Consistent Profit Alerts - newser.com

04:50 AM
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02:41 AM

What margin trends mean for Spyre Therapeutics Inc. stockLong Setup & Fast Gain Swing Trade Alerts - newser.com

02:41 AM
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02:40 AM

Is Spyre Therapeutics Inc. (3920) stock inflation resilientEarnings Trend Report & Verified Technical Trade Signals - newser.com

02:40 AM
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02:26 AM

Using data tools to time your Spyre Therapeutics Inc. exitPortfolio Profit Report & Precise Swing Trade Alerts - newser.com

02:26 AM
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01:14 AM

Is Spyre Therapeutics Inc. (3920) stock at risk of policy regulationWeekly Investment Recap & Advanced Technical Signal Analysis - newser.com

01:14 AM
pulisher
Nov 03, 2025

What sentiment indicators say about Spyre Therapeutics Inc. stockJuly 2025 Trends & Free Low Drawdown Momentum Trade Ideas - newser.com

Nov 03, 2025
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Nov 03, 2025

Why retail investors favor Spyre Therapeutics Inc. stock2025 Bull vs Bear & AI Powered Market Trend Analysis - newser.com

Nov 03, 2025
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Nov 03, 2025

Is Spyre Therapeutics Inc. stock a buy for dividend growth2025 Big Picture & Free High Return Stock Watch Alerts - newser.com

Nov 03, 2025
pulisher
Nov 03, 2025

Is a relief rally coming for Spyre Therapeutics Inc. holdersJuly 2025 Sentiment & Risk Controlled Stock Pick Alerts - newser.com

Nov 03, 2025
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Nov 03, 2025

What insider purchases suggest about Spyre Therapeutics Inc. (3920) stockMarket Movers & AI Driven Stock Reports - newser.com

Nov 03, 2025
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Nov 03, 2025

What dividend safety score for Spyre Therapeutics Inc. stockChart Signals & Free Accurate Trade Setup Notifications - newser.com

Nov 03, 2025
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Nov 03, 2025

Can Spyre Therapeutics Inc. stock sustain free cash flow growthShare Buyback & AI Powered Market Entry Strategies - newser.com

Nov 03, 2025
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Nov 03, 2025

Using Ichimoku Cloud for Spyre Therapeutics Inc. technicalsEarnings Overview Report & Weekly High Potential Stock Alerts - newser.com

Nov 03, 2025
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Nov 03, 2025

Will Spyre Therapeutics Inc. (3920) stock beat international competitionMarket Risk Report & Low Risk High Win Rate Stock Picks - newser.com

Nov 03, 2025
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Nov 03, 2025

Will Spyre Therapeutics Inc. stock deliver strong dividend growthJuly 2025 Highlights & Smart Swing Trading Alerts - newser.com

Nov 03, 2025
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Nov 03, 2025

Will Spyre Therapeutics Inc. (3920) stock sustain uptrend momentumStop Loss & Expert Verified Movement Alerts - newser.com

Nov 03, 2025
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Nov 02, 2025

Is Spyre Therapeutics Inc. (3920) stock undervalued after correction2025 Price Momentum & Consistent Growth Stock Picks - newser.com

Nov 02, 2025
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Nov 02, 2025

Will Spyre Therapeutics Inc. stock maintain dividend yieldMarket Performance Summary & Weekly High Potential Alerts - newser.com

Nov 02, 2025
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Nov 02, 2025

Will Spyre Therapeutics Inc. stock sustain high P E ratiosMarket Performance Report & Free Safe Entry Trade Signal Reports - newser.com

Nov 02, 2025
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Nov 02, 2025

Is Spyre Therapeutics Inc. stock supported by innovation pipelineJuly 2025 Snapshot & Stock Portfolio Risk Control - newser.com

Nov 02, 2025
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Nov 02, 2025

Why Spyre Therapeutics Inc. stock remains on watchlistsPortfolio Risk Report & Real-Time Market Trend Scan - newser.com

Nov 02, 2025
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Nov 02, 2025

How to escape a deep drawdown in Spyre Therapeutics Inc.July 2025 Weekly Recap & Technical Analysis for Trade Confirmation - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Published on: 2025-11-02 03:35:20 - newser.com

Nov 02, 2025
pulisher
Nov 01, 2025

Why Spyre Therapeutics Inc. stock remains undervalued2025 AllTime Highs & Smart Allocation Stock Tips - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Earnings visualization tools for Spyre Therapeutics Inc.July 2025 Patterns & Community Consensus Trade Alerts - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Published on: 2025-11-04 03:55:19 - newser.com

Nov 01, 2025

Spyre Therapeutics Inc Stock (SYRE) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$37.82
price up icon 1.31%
$29.17
price up icon 1.48%
$103.78
price up icon 1.87%
$103.83
price down icon 0.33%
biotechnology ONC
$312.49
price up icon 0.17%
$185.96
price down icon 0.34%
Cap:     |  Volume (24h):