17.14
price up icon0.47%   0.08
after-market After Hours: 17.14
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Spyre Therapeutics Inc stock is traded at $17.14, with a volume of 329.48K. It is up +0.47% in the last 24 hours and down -3.65% over the past month. Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.
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Previous Close:
$17.06
Open:
$16.91
24h Volume:
329.48K
Relative Volume:
0.60
Market Cap:
$1.04B
Revenue:
$1.23M
Net Income/Loss:
$-214.90M
P/E Ratio:
-4.158
EPS:
-4.1222
Net Cash Flow:
$-151.25M
1W Performance:
+4.83%
1M Performance:
-3.65%
6M Performance:
-6.70%
1Y Performance:
-38.37%
1-Day Range:
Value
$16.89
$17.34
1-Week Range:
Value
$15.91
$17.80
52-Week Range:
Value
$10.91
$40.26

Spyre Therapeutics Inc Stock (SYRE) Company Profile

Name
Name
Spyre Therapeutics Inc
Name
Phone
(617) 651-5940
Name
Address
221 CRESCENT STREET, WALTHAM
Name
Employee
65
Name
Twitter
Name
Next Earnings Date
2024-11-07
Name
Latest SEC Filings
Name
SYRE's Discussions on Twitter

Compare SYRE with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SYRE
Spyre Therapeutics Inc
17.14 1.03B 1.23M -214.90M -151.25M -4.1222
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
389.08 99.27B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
586.96 62.28B 14.21B 4.46B 3.56B 39.68
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
454.18 59.14B 2.46B -319.09M -52.09M -2.47
Biotechnology icon
ARGX
Argen X Se Adr
707.96 43.34B 3.06B 1.28B 447.35M 21.30
Biotechnology icon
ONC
Beone Medicines Ltd Adr
300.14 36.72B 3.81B -644.79M -669.77M -6.24

Spyre Therapeutics Inc Stock (SYRE) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-08-25 Initiated Leerink Partners Outperform
Mar-18-25 Initiated Wolfe Research Outperform
Sep-04-24 Initiated Wedbush Outperform
Jul-16-24 Initiated Evercore ISI Outperform
May-02-24 Initiated Robert W. Baird Outperform
Mar-01-24 Upgrade Wells Fargo Equal Weight → Overweight
Dec-20-23 Initiated BTIG Research Buy
Dec-11-23 Initiated Guggenheim Buy
Dec-11-23 Initiated Jefferies Buy
May-04-20 Initiated Piper Sandler Overweight
Mar-21-19 Initiated JP Morgan Overweight
Sep-04-18 Downgrade Wells Fargo Outperform → Market Perform
Apr-24-18 Initiated Evercore ISI Outperform
Mar-14-18 Reiterated Needham Buy
View All

Spyre Therapeutics Inc Stock (SYRE) Latest News

pulisher
Aug 27, 2025

Real time scanner hits for Spyre Therapeutics Inc. explainedGold Moves & AI Forecast for Swing Trade Picks - Newser

Aug 27, 2025
pulisher
Aug 27, 2025

What technical models suggest about Spyre Therapeutics Inc.’s comeback - Newser

Aug 27, 2025
pulisher
Aug 27, 2025

Is Spyre Therapeutics Inc. trending in predictive chart modelsQuarterly Profit Review & Accurate Buy Signal Alerts - Newser

Aug 27, 2025
pulisher
Aug 27, 2025

Market reaction to Spyre Therapeutics Inc.’s recent news2025 Year in Review & Fast Exit and Entry Strategy Plans - Newser

Aug 27, 2025
pulisher
Aug 27, 2025

Long term hold vs stop loss in Spyre Therapeutics Inc.Weekly Trade Analysis & Reliable Trade Execution Plans - Newser

Aug 27, 2025
pulisher
Aug 27, 2025

Relative strength of Spyre Therapeutics Inc. in sector analysisAnalyst Upgrade & Free Expert Verified Stock Movement Alerts - Newser

Aug 27, 2025
pulisher
Aug 26, 2025

Spyre Therapeutics Inc. stock trend forecastJuly 2025 Analyst Calls & Precise Buy Zone Tips - Newser

Aug 26, 2025
pulisher
Aug 26, 2025

What data driven models say about Spyre Therapeutics Inc.’s futureGap Up & Consistent Profit Focused Trading Strategies - Newser

Aug 26, 2025
pulisher
Aug 26, 2025

Can Spyre Therapeutics Inc. recover in the next quarterQuarterly Portfolio Review & Proven Capital Preservation Methods - Newser

Aug 26, 2025
pulisher
Aug 26, 2025

Is Spyre Therapeutics Inc. forming a bottoming baseTrade Signal Summary & Free Accurate Trade Setup Notifications - Newser

Aug 26, 2025
pulisher
Aug 25, 2025

Published on: 2025-08-25 08:43:40 - Newser

Aug 25, 2025
pulisher
Aug 24, 2025

Using flow based indicators on Spyre Therapeutics Inc.Weekly Risk Summary & Growth Focused Stock Reports - Newser

Aug 24, 2025
pulisher
Aug 24, 2025

Combining machine learning predictions for Spyre Therapeutics Inc.Earnings Risk Summary & Reliable Trade Execution Plans - Newser

Aug 24, 2025
pulisher
Aug 24, 2025

Traders Consider Averaging Down in Spyre Therapeutics Inc.2025 Macro Impact & Step-by-Step Swing Trade Plans - newsyoung.net

Aug 24, 2025
pulisher
Aug 24, 2025

Activity Recap: What’s the RSI of Spyre Therapeutics Inc. stock2025 Key Highlights & Free Community Consensus Stock Picks - sundaytimes.kr

Aug 24, 2025
pulisher
Aug 24, 2025

Is Spyre Therapeutics Inc. stock technically oversoldJuly 2025 Rallies & Risk Controlled Stock Alerts - sundaytimes.kr

Aug 24, 2025
pulisher
Aug 24, 2025

Will Spyre Therapeutics Inc. bounce back from current supportProduct Launch & Real-Time Stock Movement Alerts - Newser

Aug 24, 2025
pulisher
Aug 24, 2025

What is Spyre Therapeutics Inc.’s valuation compared to sector2025 Market Sentiment & Community Verified Trade Alerts - theviewers.co.kr

Aug 24, 2025
pulisher
Aug 23, 2025

FOMO Trade: What are the future prospects of Spyre Therapeutics Inc.Market Growth Report & AI Driven Stock Price Forecasts - sundaytimes.kr

Aug 23, 2025
pulisher
Aug 23, 2025

Spyre Therapeutics Inc. stock trend outlook and recovery path2025 Market Overview & Accurate Buy Signal Alerts - Newser

Aug 23, 2025
pulisher
Aug 23, 2025

Does Spyre Therapeutics Inc. have high return on assetsDay Trade & Verified Technical Signals - theviewers.co.kr

Aug 23, 2025
pulisher
Aug 23, 2025

Spyre Therapeutics Bets Big On Next-Gen IBD Pipeline - Finimize

Aug 23, 2025
pulisher
Aug 23, 2025

Can Spyre Therapeutics Inc. expand its profit marginsEarnings Growth Summary & Daily Growth Stock Investment Tips - sundaytimes.kr

Aug 23, 2025
pulisher
Aug 23, 2025

Spyre Therapeutics Inc. stock retracement – recovery analysisTake Profit & Consistent Growth Equity Picks - Newser

Aug 23, 2025
pulisher
Aug 23, 2025

How hedge fund analytics apply to Spyre Therapeutics Inc. stockEarnings Beat & Accurate Technical Buy Alerts - Newser

Aug 23, 2025
pulisher
Aug 21, 2025

Custom Dashboard Highlights Spyre Therapeutics Inc. Price MomentumMarket Growth Report & Long-Term Growth Plans - kangso.co.kr

Aug 21, 2025
pulisher
Aug 20, 2025

When is the best time to exit Spyre Therapeutics Inc.Market Performance Summary & Advanced Technical Signal Analysis - Newser

Aug 20, 2025
pulisher
Aug 20, 2025

Analyzing net buyer seller activity in Spyre Therapeutics Inc.July 2025 Sector Moves & Fast Entry and Exit Trade Plans - Newser

Aug 20, 2025
pulisher
Aug 20, 2025

How to build a dashboard for Spyre Therapeutics Inc. stock2025 Historical Comparison & Accurate Intraday Trade Tips - Newser

Aug 20, 2025
pulisher
Aug 19, 2025

RSI + MACD Show Convergence for Spyre Therapeutics Inc.2025 Valuation Update & Consistent Income Trade Ideas - newsyoung.net

Aug 19, 2025

Spyre Therapeutics Inc Stock (SYRE) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$24.78
price up icon 0.98%
$84.84
price up icon 1.00%
$24.80
price down icon 8.06%
$103.01
price down icon 1.70%
$134.53
price up icon 1.79%
biotechnology ONC
$300.14
price down icon 2.84%
Cap:     |  Volume (24h):