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Spyre Therapeutics IncSYRE
$96.562.43%-2.40

Spyre Therapeutics Inc (SYRE)

Date: 2026-10-30 16:00O: 96.78H: 98.96L: 94.68C: 96.56Vol: 658.5k
Spyre Therapeutics Inc stock is traded at $96.56, with a volume of 658,464. It is down -2.43% in the last 24 hours and up +8.46% over the past month. Spyre Therapeutics Inc is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases. Spyre's pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.
Previous Close:
$98.96
Open:
$96.78
24h Volume:
658,464
Relative Volume:
0.73
Market Cap:
$9.02B
Revenue:
$688.00K
Net Income/Loss:
-$168.74M
P/E Ratio:
-
EPS:
-$2.36
Net Cash Flow:
-$185.87M
1W Performance:
+6.90%
1M Performance:
+8.46%
6M Performance:
+29.70%
1Y Performance:
+298.02%
1-Day Range:
$94.68$98.96
1-Week Range:
$90.35$100.42
52-Week Range:
$21.15$110.18

Spyre Therapeutics Inc Stock (SYRE) Company Profile

Name
Spyre Therapeutics Inc
Phone
(617) 651-5940
Address
221 CRESCENT STREET, WALTHAM, USA
Employee
102
X
-
Next Earnings Date
2026-11-03
Latest SEC Filings
SEC
SYRE's Discussions on X
X

Compare SYRE vs VRTX, REGN, MRNA, ARGX, ONC

StocksPriceMarket CapRevenueNet IncomeCash FlowEPS
SYRE
Spyre Therapeutics Inc
$96.56$9.02B$688.00K-$168.74M-$185.87M-$2.36
VRTX
Vertex Pharmaceuticals Inc
$558.88$141.65B$12.34B$4.34B$3.71B$16.87
REGN
Regeneron Pharmaceuticals Inc
$927.89$95.53B$14.92B$4.42B$3.79B$41.04
MRNA
Moderna Inc
$221.72$88.52B$2.23B-$3.19B-$1.60B-$8.15
ARGX
Argen X Se Adr
$892.87$56.15B$4.16B$1.29B$734.26M$19.58
ONC
Beone Medicines Ltd Adr
$370.33$41.89B$5.76B$514.49M$1.10B$4.48

Spyre Therapeutics Inc Stock (SYRE) Upgrades & Downgrades

DateActionAnalystRating Change
Oct-12-26InitiatedUBSBuy
Oct-01-26InitiatedJP MorganOverweight
Jul-28-26DowngradeWolfe ResearchOutperform → Peer Perform
Apr-14-26InitiatedRaymond JamesStrong Buy

Spyre Therapeutics Inc Stock (SYRE) Financials Data

Revenue

Net Income

Cash Flow

EPS

Spyre Therapeutics Inc Stock (SYRE) Insider Trading

  • Burrows Scott LOct 01 '26
    Chief Financial Officer
    Transaction
    Sale
    Cost
    $91.83
    #Shares
    7,500
    Value ($)
    688,756
    #Shares Total
    79,762
  • CAMERON TURTLEOct 01 '26
    Director
    Transaction
    Proposed Sale
    Cost
    $89.03
    #Shares
    45,000
    Value ($)
    4,006,350
    #Shares Total
    0
  • See Remarks
    Transaction
    Sale
    Cost
    $91.03
    #Shares
    28,933
    Value ($)
    2,633,902
    #Shares Total
    2,845
  • Officer
    Transaction
    Proposed Sale
    Cost
    $89.03
    #Shares
    29,335
    Value ($)
    2,611,695
    #Shares Total
    0
  • Turtle CameronOct 01 '26
    Chief Executive Officer
    Transaction
    Sale
    Cost
    $92.01
    #Shares
    15,000
    Value ($)
    1,380,105
    #Shares Total
    537,540
  • Burrows Scott LOct 01 '26
    Chief Financial Officer
    Transaction
    Option Exercise
    Cost
    $14.50
    #Shares
    7,500
    Value ($)
    108,750
    #Shares Total
    87,262
  • Burrows Scott LSep 30 '26
    Chief Financial Officer
    Transaction
    Option Exercise
    Cost
    $14.50
    #Shares
    17,500
    Value ($)
    253,750
    #Shares Total
    97,262
  • SCOTT BURROWSSep 30 '26
    Officer
    Transaction
    Proposed Sale
    Cost
    $89.89
    #Shares
    17,500
    Value ($)
    1,573,157
    #Shares Total
    0
  • Burrows Scott LSep 30 '26
    Chief Financial Officer
    Transaction
    Sale
    Cost
    $89.89
    #Shares
    17,500
    Value ($)
    1,573,075
    #Shares Total
    79,762
  • See Remarks
    Transaction
    Sale
    Cost
    $90.00
    #Shares
    400
    Value ($)
    36,000
    #Shares Total
    2,845
Insider TradingRelationshipDateTransactionCost#SharesValue ($)#Shares Total
Burrows Scott LChief Financial OfficerOct 01 '26Sale$91.837,500688,75679,762
CAMERON TURTLEDirectorOct 01 '26Proposed Sale$89.0345,0004,006,3500
King-Jones HeidySee RemarksOct 01 '26Sale$91.0328,9332,633,9022,845
HEIDY KING-JONESOfficerOct 01 '26Proposed Sale$89.0329,3352,611,6950
Turtle CameronChief Executive OfficerOct 01 '26Sale$92.0115,0001,380,105537,540
Burrows Scott LChief Financial OfficerOct 01 '26Option Exercise$14.507,500108,75087,262
Burrows Scott LChief Financial OfficerSep 30 '26Option Exercise$14.5017,500253,75097,262
SCOTT BURROWSOfficerSep 30 '26Proposed Sale$89.8917,5001,573,1570
Burrows Scott LChief Financial OfficerSep 30 '26Sale$89.8917,5001,573,07579,762
King-Jones HeidySee RemarksSep 02 '26Sale$90.0040036,0002,845

Spyre Therapeutics Inc Stock (SYRE) Latest News

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