loading
Spyre Therapeutics Inc stock is traded at $23.61, with a volume of 776.56K. It is down -3.11% in the last 24 hours and up +49.15% over the past month. Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.
See More
Previous Close:
$24.46
Open:
$23.95
24h Volume:
776.56K
Relative Volume:
0.97
Market Cap:
$1.42B
Revenue:
$688.00K
Net Income/Loss:
$-170.19M
P/E Ratio:
-7.7423
EPS:
-3.0495
Net Cash Flow:
$-154.68M
1W Performance:
-3.54%
1M Performance:
+49.15%
6M Performance:
+56.85%
1Y Performance:
-30.25%
1-Day Range:
Value
$22.42
$24.45
1-Week Range:
Value
$22.42
$25.05
52-Week Range:
Value
$10.91
$40.26

Spyre Therapeutics Inc Stock (SYRE) Company Profile

Name
Name
Spyre Therapeutics Inc
Name
Phone
(617) 651-5940
Name
Address
221 CRESCENT STREET, WALTHAM
Name
Employee
65
Name
Twitter
Name
Next Earnings Date
2024-11-07
Name
Latest SEC Filings
Name
SYRE's Discussions on Twitter

Compare SYRE with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SYRE
Spyre Therapeutics Inc
23.58 1.90B 688.00K -170.19M -154.68M -3.0495
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
425.24 109.11B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
641.54 68.50B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
433.50 60.25B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
825.85 50.39B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
186.20 40.44B 447.02M -1.18B -868.57M -6.1812

Spyre Therapeutics Inc Stock (SYRE) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-26-25 Initiated Deutsche Bank Buy
Apr-08-25 Initiated Leerink Partners Outperform
Mar-18-25 Initiated Wolfe Research Outperform
Sep-04-24 Initiated Wedbush Outperform
Jul-16-24 Initiated Evercore ISI Outperform
May-02-24 Initiated Robert W. Baird Outperform
Mar-01-24 Upgrade Wells Fargo Equal Weight → Overweight
Dec-20-23 Initiated BTIG Research Buy
Dec-11-23 Initiated Guggenheim Buy
Dec-11-23 Initiated Jefferies Buy
May-04-20 Initiated Piper Sandler Overweight
Mar-21-19 Initiated JP Morgan Overweight
Sep-04-18 Downgrade Wells Fargo Outperform → Market Perform
Apr-24-18 Initiated Evercore ISI Outperform
Mar-14-18 Reiterated Needham Buy
View All

Spyre Therapeutics Inc Stock (SYRE) Latest News

pulisher
09:32 AM

Is Spyre Therapeutics Inc. stock a buy for dividend growth2025 Big Picture & Free High Return Stock Watch Alerts - newser.com

09:32 AM
pulisher
08:34 AM

Can a trend reversal in Spyre Therapeutics Inc. lead to recoveryJuly 2025 PreEarnings & Weekly High Momentum Picks - newser.com

08:34 AM
pulisher
07:53 AM

Is a relief rally coming for Spyre Therapeutics Inc. holdersJuly 2025 Sentiment & Risk Controlled Stock Pick Alerts - newser.com

07:53 AM
pulisher
06:48 AM

Why retail investors favor Spyre Therapeutics Inc. stockAnalyst Downgrade & Safe Entry Trade Signal Reports - newser.com

06:48 AM
pulisher
05:36 AM

Is Spyre Therapeutics Inc. (3920) stock at risk of policy regulationPortfolio Profit Report & Expert Verified Movement Alerts - newser.com

05:36 AM
pulisher
04:29 AM

Why Spyre Therapeutics Inc. stock is seen as undervaluedWeekly Investment Report & Precise Swing Trade Entry Alerts - newser.com

04:29 AM
pulisher
04:06 AM

Using data tools to time your Spyre Therapeutics Inc. exitJuly 2025 Selloffs & Smart Swing Trading Techniques - newser.com

04:06 AM
pulisher
03:22 AM

What sentiment indicators say about Spyre Therapeutics Inc. stockJuly 2025 Pullbacks & Verified Momentum Stock Watchlist - newser.com

03:22 AM
pulisher
03:12 AM

Can Spyre Therapeutics Inc. stock sustain free cash flow growthShare Buyback & AI Powered Market Entry Strategies - newser.com

03:12 AM
pulisher
03:08 AM

Using Ichimoku Cloud for Spyre Therapeutics Inc. technicalsEarnings Overview Report & Weekly High Potential Stock Alerts - newser.com

03:08 AM
pulisher
02:21 AM

Will Spyre Therapeutics Inc. (3920) stock beat international competitionMarket Risk Report & Low Risk High Win Rate Stock Picks - newser.com

02:21 AM
pulisher
02:08 AM

Will Spyre Therapeutics Inc. stock deliver strong dividend growthJuly 2025 Highlights & Smart Swing Trading Alerts - newser.com

02:08 AM
pulisher
01:17 AM

Will Spyre Therapeutics Inc. (3920) stock sustain uptrend momentumStop Loss & Expert Verified Movement Alerts - newser.com

01:17 AM
pulisher
Nov 02, 2025

Is Spyre Therapeutics Inc. (3920) stock undervalued after correction2025 Price Momentum & Consistent Growth Stock Picks - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

What insider purchases suggest about Spyre Therapeutics Inc. (3920) stockIPO Watch & Free Growth Oriented Trading Recommendations - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

What dividend safety score for Spyre Therapeutics Inc. stock2025 EndofYear Setup & High Conviction Trade Alerts - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Will Spyre Therapeutics Inc. stock sustain high P E ratiosMarket Performance Report & Free Safe Entry Trade Signal Reports - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Is Spyre Therapeutics Inc. stock supported by innovation pipelineJuly 2025 Snapshot & Stock Portfolio Risk Control - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Why Spyre Therapeutics Inc. stock remains on watchlistsPortfolio Risk Report & Real-Time Market Trend Scan - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

How to escape a deep drawdown in Spyre Therapeutics Inc.July 2025 Weekly Recap & Technical Analysis for Trade Confirmation - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Will Spyre Therapeutics Inc. stock recover faster than peers2025 EndofYear Setup & Growth Focused Stock Reports - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Published on: 2025-11-02 03:35:20 - newser.com

Nov 02, 2025
pulisher
Nov 01, 2025

Is Spyre Therapeutics Inc. (3920) stock inflation resilient2025 Analyst Calls & Risk Managed Investment Signals - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Why Spyre Therapeutics Inc. stock remains undervalued2025 AllTime Highs & Smart Allocation Stock Tips - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Earnings visualization tools for Spyre Therapeutics Inc.July 2025 Patterns & Community Consensus Trade Alerts - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Published on: 2025-11-01 04:11:34 - newser.com

Nov 01, 2025
pulisher
Oct 31, 2025

Spyre Therapeutics (SYRE) to Release Quarterly Earnings on Thursday - MarketBeat

Oct 31, 2025
pulisher
Oct 31, 2025

Will Spyre Therapeutics Inc. stock maintain dividend yieldWeekly Trend Summary & Community Consensus Stock Picks - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

What drives Spyre Therapeutics Inc 3920 stock priceInsider Buying Signals & Free Professional Investment Consultations - earlytimes.in

Oct 31, 2025
pulisher
Oct 31, 2025

Spyre Therapeutics, Inc. $SYRE Shares Sold by Emerald Mutual Fund Advisers Trust - MarketBeat

Oct 31, 2025
pulisher
Oct 31, 2025

Best data tools to analyze Spyre Therapeutics Inc. stockJuly 2025 Action & Weekly Breakout Watchlists - newser.com

Oct 31, 2025

Spyre Therapeutics Inc Stock (SYRE) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading
$37.44
price down icon 0.29%
$28.67
price up icon 0.16%
$101.01
price up icon 8.01%
$104.29
price up icon 0.38%
biotechnology ONC
$312.34
price up icon 0.66%
$186.22
price down icon 1.94%
Cap:     |  Volume (24h):