2.76
price up icon2.60%   0.07
pre-market  Pre-market:  2.78   0.02   +0.72%
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Spero Therapeutics Inc Stock (SPRO) Price History

The historical daily chart and data for Spero Therapeutics Inc stock (SPRO), show that the latest closing stock price as of May 22, 2026, is $2.76.
  • Spero Therapeutics Inc all-time high stock price is $23.64, occurred on December 28, 2020.
  • The lowest Spero Therapeutics Inc stock price recorded was $0.5052 on April 09, 2025. Since then, Spero Therapeutics Inc's stock price has risen over 446.32% to $2.76 now.
  • The 52-week high stock price for SPRO is $3.22, representing a 16.67% increase from the current share price, occurred on July 09, 2025.
  • The 52-week low stock price for SPRO is $0.6562, indicating a -76.22% decrease from the current share price, occurred on May 27, 2025.
  • The closing price of Spero Therapeutics Inc (SPRO) stock in the beginning of 2025 was $15.15. The stock closed the year at $1.73, a loss of over -88.58% for the year.
The table below shows more information about SPRO historical price data:
Date High Low High - Low Volume % Change
May 22, 2026 $2.85 $2.69 $0.1648 545,468.0 +2.60%
May 21, 2026 $2.71 $2.56 $0.145 433,184.0 +2.28%
May 20, 2026 $2.65 $2.55 $0.095 319,553.0 +1.54%
May 19, 2026 $2.62 $2.50 $0.12 316,258.0 +0.39%
May 18, 2026 $2.79 $2.57 $0.22 917,113.0 -7.53%
May 15, 2026 $2.88 $2.69 $0.195 936,322.0 +1.09%
May 14, 2026 $2.76 $2.37 $0.39 1,605,368.0 +13.11%
May 13, 2026 $2.56 $2.42 $0.135 672,146.0 -3.94%
May 12, 2026 $2.56 $2.48 $0.0782 350,889.0 -0.39%
May 11, 2026 $2.67 $2.54 $0.13 421,174.0 -0.39%
May 08, 2026 $2.58 $2.49 $0.09 355,475.0 +1.99%
May 07, 2026 $2.62 $2.50 $0.123 566,248.0 -0.79%
May 06, 2026 $2.56 $2.44 $0.125 617,274.0 +4.55%
May 05, 2026 $2.58 $2.41 $0.175 505,625.0 -3.20%
May 04, 2026 $2.61 $2.46 $0.1477 462,338.0 +0.81%
May 01, 2026 $2.63 $2.48 $0.155 494,331.0 -1.20%
Apr 30, 2026 $2.58 $2.50 $0.08 363,857.0 -0.79%
Apr 29, 2026 $2.66 $2.47 $0.189 828,444.0 -5.24%
Apr 28, 2026 $2.73 $2.67 $0.0599 219,060.0 +0.00%

Spero Therapeutics Inc Stock (SPRO) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Spero Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of SPRO shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Spero Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Spero Therapeutics Inc Stock (SPRO) Price History 2026

Month High Low High - Low Volume % Change
May, 2026 $2.88 $2.37 $0.515 10,064,234.0 +9.96%
Apr, 2026 $2.92 $2.34 $0.585 9,625,502.0 +7.26%
Mar, 2026 $2.70 $2.11 $0.59 7,023,043.0 +7.83%
Feb, 2026 $2.49 $2.10 $0.39 7,241,855.0 -0.91%
Jan, 2026 $2.65 $2.18 $0.475 4,675,692.0 -6.01%

Spero Therapeutics Inc Stock (SPRO) Price History 2025

Month High Low High - Low Volume % Change
Dec, 2025 $2.42 $2.18 $0.24 5,797,139.0 -5.42%
Nov, 2025 $2.75 $2.21 $0.54 9,346,686.0 -1.23%
Oct, 2025 $2.52 $1.89 $0.63 24,417,670.0 +29.26%
Sep, 2025 $2.19 $1.84 $0.355 6,394,822.0 -9.18%
Aug, 2025 $2.39 $1.80 $0.59 14,837,768.0 -10.78%
Jul, 2025 $3.22 $2.16 $1.06 16,967,524.0 -20.00%
Jun, 2025 $3.09 $2.42 $0.67 41,627,304.0 +16.00%
May, 2025 $2.80 $0.57 $2.23 215,663,778.0 +279.94%
Apr, 2025 $0.829 $0.5052 $0.3238 3,544,110.0 -8.61%
Mar, 2025 $0.92 $0.70 $0.22 2,421,788.0 -7.17%
Feb, 2025 $0.9498 $0.7402 $0.2096 4,236,328.0 -9.46%
Jan, 2025 $1.13 $0.83 $0.30 4,111,604.0 -16.83%

Spero Therapeutics Inc Stock (SPRO) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $1.20 $0.9187 $0.2813 4,804,309.0 -10.53%
Nov, 2024 $1.34 $1.10 $0.24 5,962,053.0 -7.32%
Oct, 2024 $1.36 $1.01 $0.35 7,006,479.0 -8.21%
Sep, 2024 $1.42 $1.24 $0.18 2,130,900.0 -2.19%
Aug, 2024 $1.47 $1.15 $0.32 3,109,831.0 -2.84%
Jul, 2024 $1.53 $1.27 $0.26 1,988,878.0 +8.46%
Jun, 2024 $1.50 $1.25 $0.25 3,364,126.0 -8.45%
May, 2024 $1.72 $1.41 $0.31 3,240,683.0 +0.00%
Apr, 2024 $1.81 $1.37 $0.44 4,792,995.0 -17.44%
Mar, 2024 $1.89 $1.62 $0.265 10,445,857.0 +4.24%
Feb, 2024 $1.71 $1.33 $0.3801 4,745,080.0 +8.55%
Jan, 2024 $1.62 $1.35 $0.27 3,815,941.0 +3.40%
$29.96
price down icon 2.98%
$106.24
price down icon 3.00%
$92.14
price up icon 1.33%
$54.50
price up icon 1.77%
ONC ONC
$310.25
price up icon 0.20%
$151.56
price down icon 1.41%
Cap:     |  Volume (24h):