2.285
price up icon0.22%   0.005
pre-market  Pre-market:  2.29   0.005   +0.22%
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Spero Therapeutics Inc Stock (SPRO) Price History

The historical daily chart and data for Spero Therapeutics Inc stock (SPRO), show that the latest closing stock price as of December 04, 2025, is $2.285.
  • Spero Therapeutics Inc all-time high stock price is $23.64, occurred on December 28, 2020.
  • The lowest Spero Therapeutics Inc stock price recorded was $0.5052 on April 09, 2025. Since then, Spero Therapeutics Inc's stock price has risen over 352.30% to $2.285 now.
  • The 52-week high stock price for SPRO is $3.22, representing a 40.92% increase from the current share price, occurred on July 09, 2025.
  • The 52-week low stock price for SPRO is $0.5052, indicating a -77.89% decrease from the current share price, occurred on April 09, 2025.
  • The closing price of Spero Therapeutics Inc (SPRO) stock in the beginning of 2024 was $15.15. The stock closed the year at $1.73, a loss of over -88.58% for the year.
The table below shows more information about SPRO historical price data:
Date High Low High - Low Volume % Change
Dec 04, 2025 $2.33 $2.24 $0.085 226,201.0 +0.22%
Dec 03, 2025 $2.29 $2.18 $0.11 364,217.0 +3.64%
Dec 02, 2025 $2.29 $2.20 $0.09 502,406.0 -3.08%
Dec 01, 2025 $2.38 $2.26 $0.12 367,479.0 -5.42%
Nov 28, 2025 $2.42 $2.33 $0.09 136,577.0 +3.00%
Nov 26, 2025 $2.38 $2.28 $0.10 361,654.0 -0.43%
Nov 25, 2025 $2.37 $2.30 $0.07 263,801.0 -1.68%
Nov 24, 2025 $2.40 $2.33 $0.07 626,904.0 +3.03%
Nov 21, 2025 $2.33 $2.21 $0.115 170,117.0 +2.21%
Nov 20, 2025 $2.42 $2.23 $0.1887 431,218.0 -5.04%
Nov 19, 2025 $2.47 $2.33 $0.1383 512,498.0 -3.64%
Nov 18, 2025 $2.49 $2.37 $0.12 325,362.0 +1.65%
Nov 17, 2025 $2.57 $2.41 $0.16 633,900.0 +0.83%
Nov 14, 2025 $2.48 $2.33 $0.1469 251,110.0 -1.23%
Nov 13, 2025 $2.72 $2.43 $0.287 863,940.0 -8.27%
Nov 12, 2025 $2.75 $2.61 $0.14 751,710.0 +1.53%
Nov 11, 2025 $2.65 $2.50 $0.155 675,228.0 +4.80%
Nov 10, 2025 $2.57 $2.45 $0.12 480,814.0 +1.63%
Nov 07, 2025 $2.46 $2.35 $0.11 514,706.0 +2.93%
Nov 06, 2025 $2.47 $2.38 $0.095 602,722.0 -1.65%
Nov 05, 2025 $2.48 $2.35 $0.13 596,055.0 +3.40%

Spero Therapeutics Inc Stock (SPRO) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Spero Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of SPRO shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Spero Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Spero Therapeutics Inc Stock (SPRO) Price History 2025

Month High Low High - Low Volume % Change
Dec, 2025 $2.38 $2.18 $0.20 1,686,504.0 -4.79%
Nov, 2025 $2.75 $2.21 $0.54 9,346,686.0 -1.23%
Oct, 2025 $2.52 $1.89 $0.63 24,417,670.0 +29.26%
Sep, 2025 $2.19 $1.84 $0.355 6,394,822.0 -9.18%
Aug, 2025 $2.39 $1.80 $0.59 14,837,768.0 -10.78%
Jul, 2025 $3.22 $2.16 $1.06 16,967,524.0 -20.00%
Jun, 2025 $3.09 $2.42 $0.67 41,627,304.0 +16.00%
May, 2025 $2.80 $0.57 $2.23 215,663,778.0 +279.94%
Apr, 2025 $0.829 $0.5052 $0.3238 3,544,110.0 -8.61%
Mar, 2025 $0.92 $0.70 $0.22 2,421,788.0 -7.17%
Feb, 2025 $0.9498 $0.7402 $0.2096 4,236,328.0 -9.46%
Jan, 2025 $1.13 $0.83 $0.30 4,111,604.0 -16.83%

Spero Therapeutics Inc Stock (SPRO) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $1.20 $0.9187 $0.2813 4,804,309.0 -10.53%
Nov, 2024 $1.34 $1.10 $0.24 5,962,053.0 -7.32%
Oct, 2024 $1.36 $1.01 $0.35 7,006,479.0 -8.21%
Sep, 2024 $1.42 $1.24 $0.18 2,130,900.0 -2.19%
Aug, 2024 $1.47 $1.15 $0.32 3,109,831.0 -2.84%
Jul, 2024 $1.53 $1.27 $0.26 1,988,878.0 +8.46%
Jun, 2024 $1.50 $1.25 $0.25 3,364,126.0 -8.45%
May, 2024 $1.72 $1.41 $0.31 3,240,683.0 +0.00%
Apr, 2024 $1.81 $1.37 $0.44 4,792,995.0 -17.44%
Mar, 2024 $1.89 $1.62 $0.265 10,445,857.0 +4.24%
Feb, 2024 $1.71 $1.33 $0.3801 4,745,080.0 +8.55%
Jan, 2024 $1.62 $1.35 $0.27 3,815,941.0 +3.40%

Spero Therapeutics Inc Stock (SPRO) Price History 2023

Month High Low High - Low Volume % Change
Dec, 2023 $1.50 $1.14 $0.36 3,836,230.0 +28.95%
Nov, 2023 $1.29 $1.04 $0.25 3,388,001.0 +5.56%
Oct, 2023 $1.21 $0.99 $0.22 3,386,494.0 -10.74%
Sep, 2023 $1.55 $1.18 $0.37 4,744,630.0 -19.33%
Aug, 2023 $1.66 $1.24 $0.42 9,557,762.0 -7.98%
Jul, 2023 $1.65 $1.36 $0.29 6,059,018.0 +12.41%
Jun, 2023 $1.83 $1.39 $0.44 6,620,793.0 -16.67%
May, 2023 $2.00 $1.71 $0.285 6,870,867.0 -1.69%
Apr, 2023 $1.80 $1.41 $0.39 8,061,520.0 +22.07%
Mar, 2023 $1.73 $1.35 $0.38 20,619,374.0 -2.03%
Feb, 2023 $1.93 $1.48 $0.455 7,022,792.0 -20.00%
Jan, 2023 $2.04 $1.71 $0.33 6,598,794.0 +6.94%
$39.16
price down icon 1.10%
$100.48
price down icon 1.00%
$32.03
price up icon 1.10%
$95.99
price down icon 0.77%
biotechnology ONC
$331.27
price down icon 1.95%
$205.04
price down icon 0.84%
Cap:     |  Volume (24h):