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Spero Therapeutics Inc Stock (SPRO) Price History

The historical daily chart and data for Spero Therapeutics Inc stock (SPRO), show that the latest closing stock price as of November 04, 2025, is $2.355.
  • Spero Therapeutics Inc all-time high stock price is $23.64, occurred on December 28, 2020.
  • The lowest Spero Therapeutics Inc stock price recorded was $0.5052 on April 09, 2025. Since then, Spero Therapeutics Inc's stock price has risen over 366.15% to $2.355 now.
  • The 52-week high stock price for SPRO is $3.22, representing a 36.73% increase from the current share price, occurred on July 09, 2025.
  • The 52-week low stock price for SPRO is $0.5052, indicating a -78.55% decrease from the current share price, occurred on April 09, 2025.
  • The closing price of Spero Therapeutics Inc (SPRO) stock in the beginning of 2024 was $15.15. The stock closed the year at $1.73, a loss of over -88.58% for the year.
The table below shows more information about SPRO historical price data:
Date High Low High - Low Volume % Change
Nov 04, 2025 $2.47 $2.33 $0.14 658,420.0 -1.05%
Nov 03, 2025 $2.46 $2.32 $0.145 444,419.0 -2.06%
Oct 31, 2025 $2.48 $2.33 $0.145 491,598.0 +2.97%
Oct 30, 2025 $2.44 $2.31 $0.13 331,806.0 +1.29%
Oct 29, 2025 $2.40 $2.30 $0.10 433,160.0 -2.10%
Oct 28, 2025 $2.42 $2.27 $0.15 579,202.0 +3.93%
Oct 27, 2025 $2.30 $2.21 $0.0876 283,063.0 +3.62%
Oct 24, 2025 $2.25 $2.19 $0.06 451,642.0 +0.45%
Oct 23, 2025 $2.28 $2.16 $0.1175 664,483.0 -2.22%
Oct 22, 2025 $2.32 $2.24 $0.08 1,147,978.0 -5.06%
Oct 21, 2025 $2.50 $2.30 $0.20 12,686,620.0 +3.49%
Oct 20, 2025 $2.32 $2.22 $0.10 371,163.0 +3.62%
Oct 17, 2025 $2.32 $2.21 $0.11 617,736.0 -5.96%
Oct 16, 2025 $2.52 $2.34 $0.18 482,531.0 -5.62%
Oct 15, 2025 $2.49 $2.36 $0.13 591,904.0 +5.51%
Oct 14, 2025 $2.38 $2.24 $0.145 448,942.0 +3.06%
Oct 13, 2025 $2.41 $2.24 $0.17 552,421.0 +1.78%
Oct 10, 2025 $2.41 $2.25 $0.16 810,212.0 -4.66%
Oct 09, 2025 $2.42 $2.32 $0.10 581,198.0 +3.51%
Oct 08, 2025 $2.35 $2.18 $0.17 794,802.0 +5.56%
Oct 07, 2025 $2.19 $2.06 $0.1286 740,177.0 +3.35%

Spero Therapeutics Inc Stock (SPRO) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Spero Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of SPRO shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Spero Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Spero Therapeutics Inc Stock (SPRO) Price History 2025

Month High Low High - Low Volume % Change
Nov, 2025 $2.47 $2.32 $0.15 1,102,839.0 -3.09%
Oct, 2025 $2.52 $1.89 $0.63 24,417,670.0 +29.26%
Sep, 2025 $2.19 $1.84 $0.355 6,394,822.0 -9.18%
Aug, 2025 $2.39 $1.80 $0.59 14,837,768.0 -10.78%
Jul, 2025 $3.22 $2.16 $1.06 16,967,524.0 -20.00%
Jun, 2025 $3.09 $2.42 $0.67 41,627,304.0 +16.00%
May, 2025 $2.80 $0.57 $2.23 215,663,778.0 +279.94%
Apr, 2025 $0.829 $0.5052 $0.3238 3,544,110.0 -8.61%
Mar, 2025 $0.92 $0.70 $0.22 2,421,788.0 -7.17%
Feb, 2025 $0.9498 $0.7402 $0.2096 4,236,328.0 -9.46%
Jan, 2025 $1.13 $0.83 $0.30 4,111,604.0 -16.83%

Spero Therapeutics Inc Stock (SPRO) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $1.20 $0.9187 $0.2813 4,804,309.0 -10.53%
Nov, 2024 $1.34 $1.10 $0.24 5,962,053.0 -7.32%
Oct, 2024 $1.36 $1.01 $0.35 7,006,479.0 -8.21%
Sep, 2024 $1.42 $1.24 $0.18 2,130,900.0 -2.19%
Aug, 2024 $1.47 $1.15 $0.32 3,109,831.0 -2.84%
Jul, 2024 $1.53 $1.27 $0.26 1,988,878.0 +8.46%
Jun, 2024 $1.50 $1.25 $0.25 3,364,126.0 -8.45%
May, 2024 $1.72 $1.41 $0.31 3,240,683.0 +0.00%
Apr, 2024 $1.81 $1.37 $0.44 4,792,995.0 -17.44%
Mar, 2024 $1.89 $1.62 $0.265 10,445,857.0 +4.24%
Feb, 2024 $1.71 $1.33 $0.3801 4,745,080.0 +8.55%
Jan, 2024 $1.62 $1.35 $0.27 3,815,941.0 +3.40%

Spero Therapeutics Inc Stock (SPRO) Price History 2023

Month High Low High - Low Volume % Change
Dec, 2023 $1.50 $1.14 $0.36 3,836,230.0 +28.95%
Nov, 2023 $1.29 $1.04 $0.25 3,388,001.0 +5.56%
Oct, 2023 $1.21 $0.99 $0.22 3,386,494.0 -10.74%
Sep, 2023 $1.55 $1.18 $0.37 4,744,630.0 -19.33%
Aug, 2023 $1.66 $1.24 $0.42 9,557,762.0 -7.98%
Jul, 2023 $1.65 $1.36 $0.29 6,059,018.0 +12.41%
Jun, 2023 $1.83 $1.39 $0.44 6,620,793.0 -16.67%
May, 2023 $2.00 $1.71 $0.285 6,870,867.0 -1.69%
Apr, 2023 $1.80 $1.41 $0.39 8,061,520.0 +22.07%
Mar, 2023 $1.73 $1.35 $0.38 20,619,374.0 -2.03%
Feb, 2023 $1.93 $1.48 $0.455 7,022,792.0 -20.00%
Jan, 2023 $2.04 $1.71 $0.33 6,598,794.0 +6.94%
$37.66
price up icon 0.92%
$28.96
price up icon 0.92%
$102.36
price up icon 0.71%
$104.36
price up icon 0.42%
biotechnology ONC
$309.99
price down icon 0.47%
$184.01
price down icon 1.33%
Cap:     |  Volume (24h):