2.3399
price down icon4.12%   -0.0901
 
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Spero Therapeutics Inc stock is traded at $2.3399, with a volume of 156.18K. It is down -4.12% in the last 24 hours and up +13.66% over the past month. Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
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Previous Close:
$2.43
Open:
$2.44
24h Volume:
156.18K
Relative Volume:
0.23
Market Cap:
$131.57M
Revenue:
$76.19M
Net Income/Loss:
$-1.61M
P/E Ratio:
233.99
EPS:
0.01
Net Cash Flow:
$28.98M
1W Performance:
+1.75%
1M Performance:
+13.66%
6M Performance:
+260.12%
1Y Performance:
+97.46%
1-Day Range:
Value
$2.33
$2.465
1-Week Range:
Value
$2.27
$2.475
52-Week Range:
Value
$0.5052
$3.22

Spero Therapeutics Inc Stock (SPRO) Company Profile

Name
Name
Spero Therapeutics Inc
Name
Phone
857-242-1600
Name
Address
675 MASSACHUSETTS AVENUE, CAMBRIDGE, MA
Name
Employee
32
Name
Twitter
@spero_tx
Name
Next Earnings Date
2025-03-19
Name
Latest SEC Filings
Name
SPRO's Discussions on Twitter

Compare SPRO with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SPRO
Spero Therapeutics Inc
2.338 136.75M 76.19M -1.61M 28.98M 0.01
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
422.97 109.11B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
632.67 68.50B 14.25B 4.58B 3.88B 41.77
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ALNY
Alnylam Pharmaceuticals Inc
434.67 60.25B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
824.64 50.39B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
181.94 40.44B 447.02M -1.18B -868.57M -6.1812

Spero Therapeutics Inc Stock (SPRO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-20-24 Downgrade Evercore ISI Outperform → In-line
Sep-23-22 Upgrade Evercore ISI In-line → Outperform
Oct-01-21 Downgrade Oppenheimer Outperform → Perform
Jan-22-21 Reiterated H.C. Wainwright Buy
Dec-16-20 Initiated Berenberg Buy
Sep-29-20 Initiated Evercore ISI Outperform
Nov-05-19 Reiterated H.C. Wainwright Buy
Sep-09-19 Initiated Janney Buy
Feb-09-18 Initiated Cantor Fitzgerald Overweight
Nov-27-17 Initiated BofA/Merrill Neutral
Nov-27-17 Initiated Oppenheimer Outperform
Nov-27-17 Initiated Stifel Buy
View All

Spero Therapeutics Inc Stock (SPRO) Latest News

pulisher
08:15 AM

How Spero Therapeutics Inc. stock compares to industry benchmarksQuarterly Portfolio Summary & AI Based Buy and Sell Signals - newser.com

08:15 AM
pulisher
06:03 AM

How Spero Therapeutics Inc. stock reacts to inflationary pressuresPortfolio Return Summary & Fast Gaining Stock Strategy Reports - newser.com

06:03 AM
pulisher
04:36 AM

Using flow based indicators on Spero Therapeutics Inc.Quarterly Growth Report & AI Driven Stock Reports - newser.com

04:36 AM
pulisher
04:27 AM

What earnings margins imply for Spero Therapeutics Inc. (2HA) stockQuarterly Profit Summary & High Win Rate Trade Tips - newser.com

04:27 AM
pulisher
Nov 02, 2025

What analysts say about Spero Therapeutics Inc stockSupport and Resistance Levels & Free Unlock Hidden Market Opportunities - earlytimes.in

Nov 02, 2025
pulisher
Nov 02, 2025

What analysts say about China Pharma Holdings Inc stockHealthcare Stock Analysis & Rapid Profit Growth - earlytimes.in

Nov 02, 2025
pulisher
Nov 02, 2025

Will Spero Therapeutics Inc. stock keep outperforming rivalsPortfolio Update Report & Risk Adjusted Swing Trade Ideas - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Will Spero Therapeutics Inc. stock sustain high P E ratiosEarnings Recap Report & Daily Profit Maximizing Tips - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Will breakout in Spero Therapeutics Inc. lead to full recoveryTrade Risk Summary & Step-by-Step Swing Trade Plans - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

What recovery options are there for Spero Therapeutics Inc.Weekly Loss Report & Free Real-Time Market Sentiment Alerts - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Spero Therapeutics, Inc. (NASDAQ:SPRO) Short Interest Down 42.5% in October - MarketBeat

Nov 02, 2025
pulisher
Nov 02, 2025

Will Spero Therapeutics Inc. benefit from macro trendsEarnings Risk Report & Long-Term Investment Growth Plans - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

How sustainable is Spero Therapeutics Inc. stock dividend payoutMarket Activity Summary & Expert Verified Stock Movement Alerts - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

What does recent volatility data suggest for Spero Therapeutics Inc.Quarterly Market Summary & Stepwise Swing Trade Plans - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Is Spero Therapeutics Inc. (2HA) stock undervalued historicallyTrade Volume Report & Free Technical Confirmation Trade Alerts - newser.com

Nov 02, 2025
pulisher
Nov 01, 2025

Published on: 2025-11-01 09:23:51 - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Will Spero Therapeutics Inc. stock recover after recent drop2025 Market Outlook & Fast Exit and Entry Strategy Plans - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Spero Therapeutics Inc. stock daily chart insights2025 Trading Volume Trends & High Accuracy Swing Trade Signals - newser.com

Nov 01, 2025
pulisher
Oct 31, 2025

Will Spero Therapeutics Inc. stock pay special dividendsMarket Activity Report & Daily Profit Focused Stock Screening - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Published on: 2025-10-31 10:27:16 - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Why Spero Therapeutics Inc. (2HA) stock is trending on social mediaWeekly Earnings Recap & Verified Momentum Stock Alerts - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

How to monitor Spero Therapeutics Inc. with trend dashboards2025 Trading Volume Trends & Daily Stock Trend Watchlist - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Will Spero Therapeutics Inc. stock remain a Wall Street favoriteMarket Trend Summary & Entry Point Confirmation Alerts - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Why Spero Therapeutics Inc. (2HA) stock is listed among top recommendationsWeekly Trade Summary & Accurate Entry and Exit Point Alerts - newser.com

Oct 31, 2025
pulisher
Oct 30, 2025

Published on: 2025-10-30 05:46:40 - newser.com

Oct 30, 2025
pulisher
Oct 30, 2025

What MACD signals say about Spero Therapeutics Inc.Market Trend Report & Weekly Stock Breakout Alerts - newser.com

Oct 30, 2025

Spero Therapeutics Inc Stock (SPRO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$37.23
price down icon 0.68%
$92.89
price down icon 0.72%
$28.92
price up icon 0.96%
$104.23
price up icon 0.19%
biotechnology ONC
$312.02
price up icon 0.74%
$182.66
price down icon 3.82%
Cap:     |  Volume (24h):