1.87

0.54% 0.01

Spero Therapeutics Inc (SPRO)

Overview News Price History Option Chain Financials Discussions Forecast

Spero Therapeutics Inc stock is traded at $1.87, with a volume of 297.79K. It is up +0.54% in the last 24 hours and down -22.41% over the past month. Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.

Previous Close:

$1.86

Open:

$1.89

24h Volume:

297.79K

Relative Volume:

0.07

Market Cap:

$105.23M

Revenue:

$76.19M

Net Income/Loss:

$-1.61M

P/E Ratio:

187.00

EPS:

0.01

Net Cash Flow:

$28.98M

1W Performance:

-2.09%

1M Performance:

-22.41%

6M Performance:

+125.03%

1Y Performance:

+38.52%

1-Day Range:

$1.86

$1.9444

1-Week Range:

$1.80

$1.9444

52-Week Range:

$0.5052

$3.22

Spero Therapeutics Inc Stock (SPRO) Company Profile

Name

Spero Therapeutics Inc

Sector

Healthcare (1157)

Industry

Biotechnology (645)

Phone

857-242-1600

Address

675 MASSACHUSETTS AVENUE, CAMBRIDGE, MA

Employee

Twitter

@spero_tx

Next Earnings Date

2025-03-19

Latest SEC Filings

SPRO's Discussions on Twitter

Compare SPRO with other stocks

Stocks	Price	Market Cap	Revenue	Net Income	Cash Flow	EPS
SPRO Spero Therapeutics Inc	1.87	107.49M	76.19M	-1.61M	28.98M	0.01
VRTX Vertex Pharmaceuticals Inc	395.12	99.96B	11.39B	3.64B	3.50B	13.99
REGN Regeneron Pharmaceuticals Inc	589.48	60.83B	14.21B	4.46B	3.56B	39.68
ALNY Alnylam Pharmaceuticals Inc	454.38	59.89B	2.46B	-319.09M	-52.09M	-2.47
ARGX Argen X Se Adr	660.00	40.47B	3.06B	1.28B	447.35M	21.30
ONC Beone Medicines Ltd Adr	313.67	37.96B	3.81B	-644.79M	-669.77M	-6.24

Spero Therapeutics Inc Stock (SPRO) Upgrades & Downgrades

Date	Action	Analyst	Rating Change
Dec-20-24	Downgrade	Evercore ISI	Outperform → In-line
Sep-23-22	Upgrade	Evercore ISI	In-line → Outperform
Oct-01-21	Downgrade	Oppenheimer	Outperform → Perform
Jan-22-21	Reiterated	H.C. Wainwright	Buy
Dec-16-20	Initiated	Berenberg	Buy
Sep-29-20	Initiated	Evercore ISI	Outperform
Nov-05-19	Reiterated	H.C. Wainwright	Buy
Sep-09-19	Initiated	Janney	Buy
Feb-09-18	Initiated	Cantor Fitzgerald	Overweight
Nov-27-17	Initiated	BofA/Merrill	Neutral
Nov-27-17	Initiated	Oppenheimer	Outperform
Nov-27-17	Initiated	Stifel	Buy

View All

Spero Therapeutics Inc Stock (SPRO) Latest News

Aug 19, 2025

Down 17.7% in 4 Weeks, Here's Why Spero Therapeutics (SPRO) Looks Ripe for a Turnaround - Yahoo Finance

Aug 19, 2025

Aug 18, 2025

Spero Therapeutics Inc. Shows Support at Fibonacci Level2025 Major Catalysts & Safe Capital Growth Stock Tips - beatles.ru

Aug 18, 2025

Is Spero Therapeutics Inc. in a long term uptrend2025 Buyback Activity & Fast Gain Swing Trade Alerts - thegnnews.com

Aug 18, 2025

Aug 16, 2025

Momentum divergence signals in Spero Therapeutics Inc. chartMarket Volume Summary & Consistent Return Investment Signals - Newser

Aug 16, 2025

Chart overlay techniques for tracking Spero Therapeutics Inc.Gap Down & Precise Buy Zone Tips - Newser

Aug 16, 2025

Using portfolio simulators with Spero Therapeutics Inc. includedSwing Trade & Reliable Trade Execution Plans - Newser

Aug 16, 2025

Aug 15, 2025

Measuring Spero Therapeutics Inc.’s beta against major indicesJuly 2025 Opening Moves & Real-Time Buy Signal Alerts - Newser

Aug 15, 2025

Using data tools to time your Spero Therapeutics Inc. exitWeekly Volume Report & Weekly Market Pulse Updates - Newser

Aug 15, 2025

Technical analysis overview for Spero Therapeutics Inc. stockWeekly Investment Summary & AI Powered Trade Plan Recommendations - Newser

Aug 15, 2025

Is Spero Therapeutics Inc. subject to activist investor interestInsider Selling & Trade Opportunity Analysis - thegnnews.com

Aug 15, 2025

Is Spero Therapeutics Inc. gaining market share2025 Volume Leaders & Risk Adjusted Buy/Sell Alerts - newsyoung.net

Aug 15, 2025

Aug 14, 2025

SPRO’s 2025 Market Dance: Up 51.17% – Time to Invest? - investchronicle.com

Aug 14, 2025

Price Consolidation Hints at Upcoming Move in Spero Therapeutics Inc.July 2025 Pullbacks & Fast Entry Momentum Trade Alerts - newsyoung.net

Aug 14, 2025

Aug 13, 2025

Spero Therapeutics’ Positive Earnings Call Highlights - TipRanks

Aug 13, 2025

Spero Therapeutics, Inc. (NASDAQ:SPRO) Q2 2025 Earnings Call Transcript - Insider Monkey

Aug 13, 2025

Spero Therapeutics Reports Q2 2025 Financial Results - MSN

Aug 13, 2025