2.285
price up icon0.22%   0.005
pre-market  Pre-market:  2.29   0.005   +0.22%
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Spero Therapeutics Inc stock is traded at $2.285, with a volume of 226.20K. It is up +0.22% in the last 24 hours and down -2.77% over the past month. Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
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Previous Close:
$2.28
Open:
$2.27
24h Volume:
226.20K
Relative Volume:
0.36
Market Cap:
$128.74M
Revenue:
$76.19M
Net Income/Loss:
$-1.61M
P/E Ratio:
228.50
EPS:
0.01
Net Cash Flow:
$28.98M
1W Performance:
-1.93%
1M Performance:
-2.77%
6M Performance:
-14.10%
1Y Performance:
+93.64%
1-Day Range:
Value
$2.24
$2.325
1-Week Range:
Value
$2.18
$2.42
52-Week Range:
Value
$0.5052
$3.22

Spero Therapeutics Inc Stock (SPRO) Company Profile

Name
Name
Spero Therapeutics Inc
Name
Phone
857-242-1600
Name
Address
675 MASSACHUSETTS AVENUE, CAMBRIDGE, MA
Name
Employee
32
Name
Twitter
@spero_tx
Name
Next Earnings Date
2025-03-19
Name
Latest SEC Filings
Name
SPRO's Discussions on Twitter

Compare SPRO with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SPRO
Spero Therapeutics Inc
2.285 128.45M 76.19M -1.61M 28.98M 0.01
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
457.26 117.50B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
722.83 76.06B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
464.56 62.53B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
916.31 56.75B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
205.04 44.10B 447.02M -1.18B -906.14M -6.1812

Spero Therapeutics Inc Stock (SPRO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-20-24 Downgrade Evercore ISI Outperform → In-line
Sep-23-22 Upgrade Evercore ISI In-line → Outperform
Oct-01-21 Downgrade Oppenheimer Outperform → Perform
Jan-22-21 Reiterated H.C. Wainwright Buy
Dec-16-20 Initiated Berenberg Buy
Sep-29-20 Initiated Evercore ISI Outperform
Nov-05-19 Reiterated H.C. Wainwright Buy
Sep-09-19 Initiated Janney Buy
Feb-09-18 Initiated Cantor Fitzgerald Overweight
Nov-27-17 Initiated BofA/Merrill Neutral
Nov-27-17 Initiated Oppenheimer Outperform
Nov-27-17 Initiated Stifel Buy
View All

Spero Therapeutics Inc Stock (SPRO) Latest News

pulisher
Dec 04, 2025

Can Spero Therapeutics Inc. (2HA) stock test all time highsMarket Risk Report & Free Low Drawdown Momentum Trade Ideas - Newser

Dec 04, 2025
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Dec 04, 2025

Will Spero Therapeutics Inc. (2HA) stock benefit from sector leadership2025 Top Gainers & Free Weekly Watchlist of Top Performers - Newser

Dec 04, 2025
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Dec 04, 2025

Why Spero Therapeutics Inc. stock is popular among millennials2025 Market Overview & Community Consensus Picks - Newser

Dec 04, 2025
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Dec 03, 2025

How Spero Therapeutics Inc. (2HA) stock behaves in tightening cycles2025 Trading Recap & Intraday High Probability Alerts - Newser

Dec 03, 2025
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Dec 03, 2025

How Spero Therapeutics Inc. stock benefits from global expansionStock Surge & Risk Adjusted Buy/Sell Alerts - Newser

Dec 03, 2025
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Dec 03, 2025

How Spero Therapeutics Inc. (2HA) stock performs during market turbulenceJuly 2025 Reactions & Short-Term High Return Strategies - Newser

Dec 03, 2025
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Dec 02, 2025

Published on: 2025-12-02 04:03:46 - Newser

Dec 02, 2025
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Dec 02, 2025

Will Spero Therapeutics Inc. (2HA) stock remain on Wall Street radar2025 Price Momentum & Reliable Volume Spike Trade Alerts - Newser

Dec 02, 2025
pulisher
Nov 30, 2025

Spero Therapeutics, Inc. (SPRO) Reports Q4 Loss, Tops Revenue Estimates - MSN

Nov 30, 2025
pulisher
Nov 29, 2025

Spero Therapeutics (NASDAQ:SPRO) Upgraded to “Buy” at Wall Street Zen - Defense World

Nov 29, 2025
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Nov 29, 2025

What analysts say about Spero Therapeutics Inc stockTop Performing Stocks & Market Trend Real-Time Reports - earlytimes.in

Nov 29, 2025
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Nov 29, 2025

Can Silver Oak India Limited Maintain Its Share of Global Market for Its ProductStock Buy Signals & Get Free Training on Technical Indicators - earlytimes.in

Nov 29, 2025
pulisher
Nov 28, 2025

Spero Therapeutics announces inducement grant under Nasdaq listing rule - TipRanks

Nov 28, 2025
pulisher
Nov 28, 2025

Spero Therapeutics (SPRO) Awards New Employee with Restricted St - GuruFocus

Nov 28, 2025
pulisher
Nov 28, 2025

Spero Therapeutics Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) - Enidnews.com

Nov 28, 2025
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Nov 27, 2025

Breakout Move: Will Spero Therapeutics Inc. stock reach all time highs in 2025 - moha.gov.vn

Nov 27, 2025
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Nov 26, 2025

Aug Mood: Will Spero Therapeutics Inc. stock reach all time highs in 2025July 2025 Patterns & AI Forecasted Entry and Exit Points - BỘ NỘI VỤ

Nov 26, 2025
pulisher
Nov 22, 2025

Spero Therapeutics (NASDAQ:SPRO) Shares Cross Above 200-Day Moving Average – Should You Sell? - Defense World

Nov 22, 2025
pulisher
Nov 20, 2025

Global NTM Infections Pipeline Poised for Growth as Breakthrough Therapies Advance Toward Late-Stage Development, states DelveInsight - The Globe and Mail

Nov 20, 2025
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Nov 20, 2025

What is Spero Therapeutics Inc (SPRO) Stock Return on Shareholders’ Capital? - Setenews

Nov 20, 2025
pulisher
Nov 20, 2025

Why Spero Therapeutics Inc. (2HA) stock is favored by hedge fundsJuly 2025 Final Week & Free Weekly Chart Analysis and Trade Guides - newser.com

Nov 20, 2025
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Nov 20, 2025

Will Spero Therapeutics Inc. stock attract ESG investorsWeekly Trade Recap & Verified Swing Trading Watchlists - newser.com

Nov 20, 2025
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Nov 20, 2025

How Spero Therapeutics Inc. (2HA) stock reacts to stronger dollarBear Alert & Low Drawdown Momentum Trade Ideas - newser.com

Nov 20, 2025
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Nov 20, 2025

What technical patterns form on Spero Therapeutics Inc. (2HA) stock chartsWeekly Profit Recap & AI Driven Price Forecasts - newser.com

Nov 20, 2025
pulisher
Nov 19, 2025

Will Spero Therapeutics Inc. stock deliver strong dividend growth2025 Risk Factors & AI Forecasted Entry and Exit Points - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Will Spero Therapeutics Inc. benefit from macro trendsEntry Point & Safe Entry Zone Tips - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Published on: 2025-11-19 17:07:59 - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

How Spero Therapeutics Inc. stock reacts to inflationary pressuresTrade Analysis Summary & Real-Time Price Movement Reports - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Published on: 2025-11-19 18:54:15 - newser.com

Nov 19, 2025
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Nov 19, 2025

Why Spero Therapeutics Inc. stock is favored by pension fundsJuly 2025 Big Picture & Safe Entry Momentum Stock Tips - newser.com

Nov 19, 2025
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Nov 19, 2025

Will Spero Therapeutics Inc. stock pay special dividendsMarket Growth Summary & Real-Time Volume Trigger Notifications - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

How Spero Therapeutics Inc. stock compares to industry benchmarks - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Spero Therapeutics: A High-Stakes Bet on a Single Drug - Ad-hoc-news.de

Nov 19, 2025
pulisher
Nov 19, 2025

Is Spero Therapeutics Inc. (2HA) stock undervalued historicallyWeekly Market Report & Accurate Intraday Trading Signals - newser.com

Nov 19, 2025

Spero Therapeutics Inc Stock (SPRO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$39.16
price down icon 1.10%
$100.48
price down icon 1.00%
$32.03
price up icon 1.10%
$95.99
price down icon 0.77%
biotechnology ONC
$331.27
price down icon 1.95%
$205.04
price down icon 0.84%
Cap:     |  Volume (24h):