5.75
price down icon2.38%   -0.14
after-market After Hours: 5.75
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Karyopharm Therapeutics Inc Stock (KPTI) Price History

The historical daily chart and data for Karyopharm Therapeutics Inc stock (KPTI), show that the latest closing stock price as of December 05, 2025, is $5.75.
  • Karyopharm Therapeutics Inc all-time high stock price is $49.01, occurred on December 08, 2014.
  • The lowest Karyopharm Therapeutics Inc stock price recorded was $0.5074 on February 24, 2025. Since then, Karyopharm Therapeutics Inc's stock price has risen over 1,033% to $5.75 now.
  • The 52-week high stock price for KPTI is $12.45, representing a 116.52% increase from the current share price, occurred on January 03, 2025.
  • The 52-week low stock price for KPTI is $3.51, indicating a -38.96% decrease from the current share price, occurred on April 01, 2025.
  • The closing price of Karyopharm Therapeutics Inc (KPTI) stock in the beginning of 2024 was $7.09. The stock closed the year at $3.40, a loss of over -52.05% for the year.
The table below shows more information about KPTI historical price data:
Date High Low High - Low Volume % Change
Dec 05, 2025 $5.95 $5.74 $0.21 64,485.0 -2.38%
Dec 04, 2025 $6.04 $5.37 $0.677 125,289.0 +7.88%
Dec 03, 2025 $5.52 $5.30 $0.22 288,880.0 +1.87%
Dec 02, 2025 $5.80 $5.34 $0.46 120,821.0 -6.78%
Dec 01, 2025 $6.15 $5.48 $0.67 256,797.0 +2.31%
Nov 28, 2025 $5.71 $5.46 $0.245 45,688.0 +1.26%
Nov 26, 2025 $5.66 $5.37 $0.2889 113,030.0 +1.83%
Nov 25, 2025 $5.67 $5.31 $0.36 118,422.0 -1.98%
Nov 24, 2025 $5.93 $5.56 $0.37 103,125.0 -5.76%
Nov 21, 2025 $5.95 $5.60 $0.3467 61,567.0 +2.43%
Nov 20, 2025 $6.10 $5.70 $0.40 102,864.0 -3.68%
Nov 19, 2025 $6.50 $5.80 $0.6999 220,067.0 -4.17%
Nov 18, 2025 $6.43 $5.73 $0.70 131,648.0 +7.77%
Nov 17, 2025 $6.06 $5.53 $0.5274 142,596.0 +1.94%
Nov 14, 2025 $5.85 $5.40 $0.45 95,335.0 +3.27%
Nov 13, 2025 $5.70 $5.35 $0.3544 56,225.0 -1.61%
Nov 12, 2025 $5.65 $5.41 $0.24 56,561.0 +2.38%
Nov 11, 2025 $5.71 $5.25 $0.46 69,674.0 +0.37%
Nov 10, 2025 $5.45 $5.14 $0.31 70,237.0 +5.43%
Nov 07, 2025 $5.28 $5.01 $0.27 91,770.0 -1.15%
Nov 06, 2025 $5.45 $5.09 $0.36 94,401.0 -2.61%
Nov 05, 2025 $5.71 $5.34 $0.3781 65,250.0 -5.13%

Karyopharm Therapeutics Inc Stock (KPTI) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Karyopharm Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of KPTI shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Karyopharm Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Karyopharm Therapeutics Inc Stock (KPTI) Price History 2025

Month High Low High - Low Volume % Change
Dec, 2025 $6.15 $5.30 $0.85 920,757.0 +2.31%
Nov, 2025 $6.50 $5.01 $1.49 2,027,193.0 -3.10%
Oct, 2025 $6.75 $4.51 $2.24 6,585,420.0 -11.31%
Sep, 2025 $7.90 $5.32 $2.58 2,016,591.0 -8.02%
Aug, 2025 $8.15 $3.65 $4.50 4,418,861.0 +86.61%
Jul, 2025 $5.14 $3.70 $1.44 4,241,871.0 -11.60%
Jun, 2025 $4.77 $4.06 $0.71 1,189,321.0 +2.62%
May, 2025 $7.90 $4.15 $3.75 1,779,194.0 -37.78%
Apr, 2025 $6.79 $3.51 $3.28 2,471,648.0 +80.48%
Mar, 2025 $8.45 $3.73 $4.72 3,029,362.0 -52.96%
Feb, 2025 $10.38 $7.61 $2.77 2,032,715.1 -14.80%
Jan, 2025 $12.45 $9.19 $3.26 1,016,785.3 -8.01%

Karyopharm Therapeutics Inc Stock (KPTI) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $12.90 $8.71 $4.19 1,684,640.1 -17.16%
Nov, 2024 $15.30 $11.28 $4.02 881,980.1 -14.62%
Oct, 2024 $16.95 $11.10 $5.85 1,422,450.9 +19.25%
Sep, 2024 $12.45 $10.20 $2.25 874,153.8 +9.18%
Aug, 2024 $15.30 $11.26 $4.04 792,476.7 -23.12%
Jul, 2024 $16.95 $11.55 $5.40 1,554,208.9 +13.97%
Jun, 2024 $17.40 $13.01 $4.39 2,346,094.0 -10.47%
May, 2024 $18.00 $13.65 $4.35 1,954,419.7 -5.91%
Apr, 2024 $24.75 $15.30 $9.45 1,684,240.6 -31.79%
Mar, 2024 $25.50 $16.95 $8.55 1,631,233.2 +30.17%
Feb, 2024 $29.25 $11.55 $17.70 4,090,314.0 +54.56%
Jan, 2024 $14.03 $9.83 $4.19 1,484,176.4 -13.24%

Karyopharm Therapeutics Inc Stock (KPTI) Price History 2023

Month High Low High - Low Volume % Change
Dec, 2023 $14.82 $9.26 $5.56 1,999,289.6 +12.34%
Nov, 2023 $14.56 $10.05 $4.51 1,345,465.9 -11.49%
Oct, 2023 $20.70 $11.44 $9.26 1,384,842.0 -35.07%
Sep, 2023 $21.60 $16.65 $4.95 2,005,155.2 +4.69%
Aug, 2023 $28.20 $19.05 $9.15 2,283,931.8 -28.89%
Jul, 2023 $27.30 $21.60 $5.70 5,329,628.9 +0.56%
Jun, 2023 $37.05 $26.85 $10.20 4,851,212.0 -20.80%
May, 2023 $57.98 $32.92 $25.05 4,176,334.5 -36.87%
Apr, 2023 $73.05 $50.55 $22.50 2,921,858.7 -7.97%
Mar, 2023 $60.90 $42.52 $18.37 3,982,772.8 +28.81%
Feb, 2023 $57.45 $44.55 $12.90 2,698,426.4 -8.48%
Jan, 2023 $54.60 $40.50 $14.10 4,425,568.0 -2.94%
$39.73
price up icon 1.44%
$31.74
price down icon 0.91%
$102.52
price up icon 2.03%
$96.25
price up icon 0.27%
biotechnology ONC
$322.63
price down icon 2.61%
$204.00
price down icon 0.51%
Cap:     |  Volume (24h):