5.21
price down icon4.23%   -0.23
pre-market  Pre-market:  5.19   -0.02   -0.38%
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Karyopharm Therapeutics Inc Stock (KPTI) Price History

The historical daily chart and data for Karyopharm Therapeutics Inc stock (KPTI), show that the latest closing stock price as of March 25, 2026, is $5.21.
  • Karyopharm Therapeutics Inc all-time high stock price is $49.01, occurred on December 08, 2014.
  • The lowest Karyopharm Therapeutics Inc stock price recorded was $0.5074 on February 24, 2025. Since then, Karyopharm Therapeutics Inc's stock price has risen over 926.80% to $5.21 now.
  • The 52-week high stock price for KPTI is $10.99, representing a 110.94% increase from the current share price, occurred on February 24, 2026.
  • The 52-week low stock price for KPTI is $3.51, indicating a -32.63% decrease from the current share price, occurred on April 01, 2025.
  • The closing price of Karyopharm Therapeutics Inc (KPTI) stock in the beginning of 2025 was $7.09. The stock closed the year at $3.40, a loss of over -52.05% for the year.
The table below shows more information about KPTI historical price data:
Date High Low High - Low Volume % Change
Mar 25, 2026 $5.71 $5.09 $0.615 1,650,918.0 -4.23%
Mar 24, 2026 $6.50 $5.14 $1.36 17,831,205.0 -18.32%
Mar 23, 2026 $7.58 $6.57 $1.01 964,651.0 -12.71%
Mar 20, 2026 $9.04 $7.43 $1.60 1,488,044.0 -1.29%
Mar 19, 2026 $8.62 $7.73 $0.8851 751,100.0 -7.98%
Mar 18, 2026 $8.68 $7.96 $0.72 501,657.0 +0.24%
Mar 17, 2026 $8.60 $7.97 $0.63 702,272.0 -1.99%
Mar 16, 2026 $8.63 $7.86 $0.77 551,111.0 +8.92%
Mar 13, 2026 $8.26 $7.29 $0.97 696,493.0 -0.63%
Mar 12, 2026 $8.90 $7.64 $1.26 912,046.0 -9.71%
Mar 11, 2026 $8.85 $7.96 $0.895 460,880.0 +6.32%
Mar 10, 2026 $8.94 $8.21 $0.73 598,852.0 -3.06%
Mar 09, 2026 $8.96 $8.25 $0.71 721,290.0 -3.19%
Mar 06, 2026 $9.11 $8.57 $0.54 725,190.0 -0.57%
Mar 05, 2026 $9.17 $8.68 $0.49 509,394.0 -3.61%
Mar 04, 2026 $9.54 $8.96 $0.58 397,581.0 +0.22%
Mar 03, 2026 $9.59 $9.03 $0.56 1,717,501.0 -4.80%
Mar 02, 2026 $9.83 $8.75 $1.08 507,371.0 +1.91%
Feb 27, 2026 $9.55 $9.02 $0.535 529,768.0 +0.64%
Feb 26, 2026 $10.11 $9.16 $0.95 576,018.0 -7.33%
Feb 25, 2026 $10.38 $9.95 $0.425 478,976.0 +0.20%
Feb 24, 2026 $10.99 $9.78 $1.21 609,737.0 +0.40%

Karyopharm Therapeutics Inc Stock (KPTI) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Karyopharm Therapeutics Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of KPTI shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Karyopharm Therapeutics Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Karyopharm Therapeutics Inc Stock (KPTI) Price History 2026

Month High Low High - Low Volume % Change
Mar, 2026 $9.83 $5.09 $4.74 33,338,474.0 -44.63%
Feb, 2026 $10.99 $5.90 $5.09 13,917,099.0 +44.33%
Jan, 2026 $8.95 $5.88 $3.07 8,553,800.0 -11.41%

Karyopharm Therapeutics Inc Stock (KPTI) Price History 2025

Month High Low High - Low Volume % Change
Dec, 2025 $7.70 $5.30 $2.40 5,431,772.0 +30.07%
Nov, 2025 $6.50 $5.01 $1.49 2,027,193.0 -3.10%
Oct, 2025 $6.75 $4.51 $2.24 6,585,420.0 -11.31%
Sep, 2025 $7.90 $5.32 $2.58 2,016,591.0 -8.02%
Aug, 2025 $8.15 $3.65 $4.50 4,418,861.0 +86.61%
Jul, 2025 $5.14 $3.70 $1.44 4,241,871.0 -11.60%
Jun, 2025 $4.77 $4.06 $0.71 1,189,321.0 +2.62%
May, 2025 $7.90 $4.15 $3.75 1,779,194.0 -37.78%
Apr, 2025 $6.79 $3.51 $3.28 2,471,648.0 +80.48%
Mar, 2025 $8.45 $3.73 $4.72 3,029,362.0 -52.96%
Feb, 2025 $10.38 $7.61 $2.77 2,032,715.1 -14.80%
Jan, 2025 $12.45 $9.19 $3.26 1,016,785.3 -8.01%

Karyopharm Therapeutics Inc Stock (KPTI) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $12.90 $8.71 $4.19 1,684,640.1 -17.16%
Nov, 2024 $15.30 $11.28 $4.02 881,980.1 -14.62%
Oct, 2024 $16.95 $11.10 $5.85 1,422,450.9 +19.25%
Sep, 2024 $12.45 $10.20 $2.25 874,153.8 +9.18%
Aug, 2024 $15.30 $11.26 $4.04 792,476.7 -23.12%
Jul, 2024 $16.95 $11.55 $5.40 1,554,208.9 +13.97%
Jun, 2024 $17.40 $13.01 $4.39 2,346,094.0 -10.47%
May, 2024 $18.00 $13.65 $4.35 1,954,419.7 -5.91%
Apr, 2024 $24.75 $15.30 $9.45 1,684,240.6 -31.79%
Mar, 2024 $25.50 $16.95 $8.55 1,631,233.2 +30.17%
Feb, 2024 $29.25 $11.55 $17.70 4,090,314.0 +54.56%
Jan, 2024 $14.03 $9.83 $4.19 1,484,176.4 -13.24%
$27.36
price up icon 1.82%
$47.03
price up icon 3.20%
$53.54
price up icon 4.29%
$88.77
price up icon 2.26%
ONC ONC
$283.45
price up icon 2.81%
$148.31
price up icon 6.59%
Cap:     |  Volume (24h):