6.735
price down icon4.87%   -0.345
after-market After Hours: 6.64 -0.095 -1.41%
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Karyopharm Therapeutics Inc stock is traded at $6.735, with a volume of 52,712. It is down -4.87% in the last 24 hours and up +67.54% over the past month. Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company pioneering novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company derives its revenue from United States.
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Previous Close:
$7.08
Open:
$7.12
24h Volume:
52,712
Relative Volume:
0.35
Market Cap:
$58.40M
Revenue:
$137.27M
Net Income/Loss:
$-123.57M
P/E Ratio:
-0.6151
EPS:
-10.95
Net Cash Flow:
$-102.89M
1W Performance:
-12.30%
1M Performance:
+67.54%
6M Performance:
+5.73%
1Y Performance:
-37.00%
1-Day Range:
Value
$6.70
$7.17
1-Week Range:
Value
$6.6386
$7.721
52-Week Range:
Value
$3.51
$16.95

Karyopharm Therapeutics Inc Stock (KPTI) Company Profile

Name
Name
Karyopharm Therapeutics Inc
Name
Phone
617-658-0600
Name
Address
85 WELLS AVENUE, NEWTON, MA
Name
Employee
279
Name
Twitter
@Karyopharm
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
KPTI's Discussions on Twitter

Compare KPTI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
KPTI
Karyopharm Therapeutics Inc
6.735 58.79M 137.27M -123.57M -102.89M -10.95
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VRTX
Vertex Pharmaceuticals Inc
396.93 102.81B 11.39B 3.64B 3.50B 13.99
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ALNY
Alnylam Pharmaceuticals Inc
453.54 58.59B 2.46B -319.09M -52.09M -2.47
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REGN
Regeneron Pharmaceuticals Inc
567.22 61.25B 14.21B 4.46B 3.56B 39.68
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ARGX
Argen X Se Adr
733.66 43.23B 3.06B 1.28B 447.35M 21.30
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ONC
Beone Medicines Ltd Adr
318.73 36.53B 3.81B -644.79M -669.77M -6.24

Karyopharm Therapeutics Inc Stock (KPTI) Upgrades & Downgrades

Date Action Analyst Rating Change
Jul-16-25 Downgrade H.C. Wainwright Buy → Neutral
Jul-11-25 Resumed H.C. Wainwright Buy
Jan-19-23 Initiated Piper Sandler Overweight
Nov-04-22 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-09-22 Upgrade JP Morgan Underweight → Neutral
Nov-19-21 Resumed Morgan Stanley Equal-Weight
Aug-06-21 Downgrade JP Morgan Overweight → Neutral
Aug-06-21 Downgrade RBC Capital Mkts Outperform → Sector Perform
Aug-06-21 Downgrade SVB Leerink Outperform → Mkt Perform
Jul-02-20 Initiated Morgan Stanley Overweight
Mar-04-20 Initiated Barclays Overweight
Jan-17-20 Downgrade Wedbush Outperform → Neutral
Jul-23-19 Upgrade JP Morgan Neutral → Overweight
Jul-05-19 Reiterated H.C. Wainwright Buy
Jul-05-19 Reiterated Robert W. Baird Outperform
Mar-01-19 Downgrade JP Morgan Overweight → Neutral
Feb-28-19 Reiterated BofA/Merrill Underperform
Feb-27-19 Downgrade BofA/Merrill Neutral → Underperform
Jan-03-19 Upgrade BofA/Merrill Underperform → Neutral
Dec-03-18 Initiated B. Riley FBR Buy
Nov-09-18 Upgrade Wedbush Neutral → Outperform
May-24-18 Downgrade Wedbush Outperform → Neutral
Apr-02-18 Resumed Leerink Partners Outperform
Nov-15-17 Resumed H.C. Wainwright Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Sep-08-16 Reiterated H.C. Wainwright Buy
Aug-30-16 Upgrade Jefferies Hold → Buy
Aug-18-16 Initiated H.C. Wainwright Buy
Jun-28-16 Initiated Robert W. Baird Outperform
View All

Karyopharm Therapeutics Inc Stock (KPTI) Latest News

pulisher
Sep 03, 2025

Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - Eastern Progress

Sep 03, 2025
pulisher
Sep 03, 2025

Is Karyopharm Therapeutics Inc. gaining market shareCEO Change & Scalable Portfolio Growth Methods - khodrobank.com

Sep 03, 2025
pulisher
Sep 03, 2025

Can Karyopharm Therapeutics Inc. recover in the next quarterInsider Buying & Real-Time Buy Signal Notifications - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Analyzing recovery setups for Karyopharm Therapeutics Inc. investorsJuly 2025 Outlook & Technical Pattern Based Buy Signals - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Published on: 2025-09-03 09:05:10 - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Strategies to average down on Karyopharm Therapeutics Inc.July 2025 Earnings & Safe Swing Trade Setups - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Will Karyopharm Therapeutics Inc. benefit from rate cutsJuly 2025 News Drivers & Comprehensive Market Scan Reports - khodrobank.com

Sep 03, 2025
pulisher
Sep 02, 2025

What machine learning models say about Karyopharm Therapeutics Inc.Trade Exit Summary & Weekly High Potential Alerts - Newser

Sep 02, 2025
pulisher
Sep 02, 2025

Is now the right time to enter Karyopharm Therapeutics Inc.Weekly Risk Report & Fast Gain Swing Alerts - khodrobank.com

Sep 02, 2025
pulisher
Sep 02, 2025

How to use a screener to detect Karyopharm Therapeutics Inc. breakoutsStock Surge & Free Technical Confirmation Trade Alerts - Newser

Sep 02, 2025
pulisher
Sep 02, 2025

Karyopharm Therapeutics reports inducement grants under Nasdaq listing rule 5635(c)(4) - MarketScreener

Sep 02, 2025
pulisher
Sep 02, 2025

Using data tools to time your Karyopharm Therapeutics Inc. exitForecast Cut & Stock Market Timing Techniques - Newser

Sep 02, 2025
pulisher
Sep 02, 2025

Is Karyopharm Therapeutics Inc. benefiting from innovation trends2025 Volatility Report & Capital Protection Trading Alerts - خودرو بانک

Sep 02, 2025
pulisher
Sep 02, 2025

What candlestick patterns are forming on Karyopharm Therapeutics Inc.Market Rally & AI Enhanced Execution Alerts - Newser

Sep 02, 2025
pulisher
Sep 02, 2025

Karyopharm Therapeutics Inc. stock daily chart insightsQuarterly Market Review & Accurate Buy Signal Notifications - Newser

Sep 02, 2025
pulisher
Sep 02, 2025

What high frequency data says about Karyopharm Therapeutics Inc.Weekly Stock Recap & Accurate Entry/Exit Alerts - Newser

Sep 02, 2025
pulisher
Sep 01, 2025

Can you recover from losses in Karyopharm Therapeutics Inc.July 2025 EndofMonth & Accurate Entry/Exit Alerts - Newser

Sep 01, 2025
pulisher
Sep 01, 2025

What are Karyopharm Therapeutics Inc.’s recent SEC filings showingPortfolio Growth Summary & Risk Adjusted Swing Trade Ideas - خودرو بانک

Sep 01, 2025
pulisher
Sep 01, 2025

Analyzing Karyopharm Therapeutics Inc. with multi timeframe chartsQuarterly Growth Report & Accurate Trade Setup Notifications - Newser

Sep 01, 2025
pulisher
Sep 01, 2025

How Karyopharm Therapeutics Inc. stock reacts to Fed policy changesBull Run & Real-Time Volume Spike Alerts - Newser

Sep 01, 2025
pulisher
Sep 01, 2025

Published on: 2025-09-01 11:39:57 - beatles.ru

Sep 01, 2025
pulisher
Sep 01, 2025

What momentum shifts mean for Karyopharm Therapeutics Inc.2025 Geopolitical Influence & Free Real-Time Volume Trigger Notifications - Newser

Sep 01, 2025
pulisher
Sep 01, 2025

Forecasting Karyopharm Therapeutics Inc. price range with options dataMarket Volume Report & High Accuracy Trade Signal Alerts - Newser

Sep 01, 2025
pulisher
Aug 31, 2025

How to read the order book for Karyopharm Therapeutics Inc.Market Sentiment Report & Reliable Price Action Trade Plans - Newser

Aug 31, 2025
pulisher
Aug 31, 2025

Will Karyopharm Therapeutics Inc. stock go up soon2025 Risk Factors & Low Risk High Reward Ideas - Newser

Aug 31, 2025
pulisher
Aug 31, 2025

Can Karyopharm Therapeutics Inc. hit a new high this monthChart Signals & High Win Rate Trade Alerts - Newser

Aug 31, 2025
pulisher
Aug 31, 2025

Trend analysis for Karyopharm Therapeutics Inc. this weekJuly 2025 Catalysts & Weekly Breakout Stock Alerts - Newser

Aug 31, 2025
pulisher
Aug 31, 2025

Multi factor analysis applied to Karyopharm Therapeutics Inc.July 2025 Drop Watch & Daily Stock Trend Reports - Newser

Aug 31, 2025
pulisher
Aug 30, 2025

Using AI based signals to follow Karyopharm Therapeutics Inc.Dividend Hike & Expert Approved Momentum Trade Ideas - Newser

Aug 30, 2025
pulisher
Aug 30, 2025

Karyopharm Therapeutics Inc. stock prediction for this weekTrade Volume Report & Advanced Swing Trade Entry Plans - Newser

Aug 30, 2025
pulisher
Aug 29, 2025

Is Karyopharm Therapeutics Inc. trending in predictive chart modelsPortfolio Gains Summary & Free Community Supported Trade Ideas - Newser

Aug 29, 2025
pulisher
Aug 29, 2025

Is a relief rally coming for Karyopharm Therapeutics Inc. holdersPortfolio Risk Report & Safe Entry Trade Signal Reports - Newser

Aug 29, 2025
pulisher
Aug 29, 2025

Using flow based indicators on Karyopharm Therapeutics Inc.July 2025 Rallies & Safe Capital Allocation Plans - Newser

Aug 29, 2025

Karyopharm Therapeutics Inc Stock (KPTI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Karyopharm Therapeutics Inc Stock (KPTI) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Abate Kristin
Chief Accounting Officer
Jul 22 '25
Sale
4.00
238
952
9,475
Paulson Richard A.
President and CEO
May 06 '25
Sale
7.12
236
1,680
82,503
Rangwala Reshma
EVP & Chief Medical Officer
Apr 23 '25
Sale
6.17
419
2,585
28,853
Paulson Richard A.
President and CEO
Apr 04 '25
Sale
3.74
245
916
82,739
Cheng Sohanya Roshan
EVP & Chief Commercial Officer
Mar 04 '25
Sale
6.29
3,445
21,669
34,314
Paulson Richard A.
President and CEO
Mar 04 '25
Sale
6.29
11,694
73,555
82,984
Rangwala Reshma
EVP & Chief Medical Officer
Mar 04 '25
Sale
6.29
3,587
22,562
29,272
Poulton Stuart
EVP, Chief Development Officer
Mar 04 '25
Sale
6.29
3,548
22,317
27,414
Mano Michael
SVP, General Counsel&Secretary
Mar 04 '25
Sale
6.29
2,793
17,568
21,047
Poulton Stuart
EVP, Chief Development Officer
Feb 18 '25
Sale
0.63
5,914
3,726
320,714
$85.44
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Cap:     |  Volume (24h):