7.05
price up icon6.02%   0.40
after-market After Hours: 7.08 0.03 +0.43%
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Karyopharm Therapeutics Inc stock is traded at $7.05, with a volume of 433.17K. It is up +6.02% in the last 24 hours and down -5.24% over the past month. Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company pioneering novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company derives its revenue from United States.
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Previous Close:
$6.65
Open:
$6.7
24h Volume:
433.17K
Relative Volume:
1.73
Market Cap:
$129.09M
Revenue:
$137.27M
Net Income/Loss:
$-123.57M
P/E Ratio:
-0.64
EPS:
-11.016
Net Cash Flow:
$-102.89M
1W Performance:
+18.49%
1M Performance:
-5.24%
6M Performance:
+62.07%
1Y Performance:
-31.49%
1-Day Range:
Value
$6.51
$7.14
1-Week Range:
Value
$5.875
$7.14
52-Week Range:
Value
$3.51
$10.47

Karyopharm Therapeutics Inc Stock (KPTI) Company Profile

Name
Name
Karyopharm Therapeutics Inc
Name
Phone
617-658-0600
Name
Address
85 WELLS AVENUE, NEWTON, MA
Name
Employee
279
Name
Twitter
@Karyopharm
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
KPTI's Discussions on Twitter

Compare KPTI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
KPTI
Karyopharm Therapeutics Inc
7.05 121.76M 137.27M -123.57M -102.89M -11.02
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
474.17 120.98B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
771.25 80.15B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
864.42 51.56B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
354.75 47.74B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ONC
Beone Medicines Ltd Adr
336.16 37.38B 4.98B 69.59M 525.67M 0.5197

Karyopharm Therapeutics Inc Stock (KPTI) Upgrades & Downgrades

Date Action Analyst Rating Change
Oct-13-25 Upgrade H.C. Wainwright Neutral → Buy
Jul-16-25 Downgrade H.C. Wainwright Buy → Neutral
Jul-11-25 Resumed H.C. Wainwright Buy
Jan-19-23 Initiated Piper Sandler Overweight
Nov-04-22 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-09-22 Upgrade JP Morgan Underweight → Neutral
Nov-19-21 Resumed Morgan Stanley Equal-Weight
Aug-06-21 Downgrade JP Morgan Overweight → Neutral
Aug-06-21 Downgrade RBC Capital Mkts Outperform → Sector Perform
Aug-06-21 Downgrade SVB Leerink Outperform → Mkt Perform
Jul-02-20 Initiated Morgan Stanley Overweight
Mar-04-20 Initiated Barclays Overweight
Jan-17-20 Downgrade Wedbush Outperform → Neutral
Jul-23-19 Upgrade JP Morgan Neutral → Overweight
Jul-05-19 Reiterated H.C. Wainwright Buy
Jul-05-19 Reiterated Robert W. Baird Outperform
Mar-01-19 Downgrade JP Morgan Overweight → Neutral
Feb-28-19 Reiterated BofA/Merrill Underperform
Feb-27-19 Downgrade BofA/Merrill Neutral → Underperform
Jan-03-19 Upgrade BofA/Merrill Underperform → Neutral
Dec-03-18 Initiated B. Riley FBR Buy
Nov-09-18 Upgrade Wedbush Neutral → Outperform
May-24-18 Downgrade Wedbush Outperform → Neutral
Apr-02-18 Resumed Leerink Partners Outperform
Nov-15-17 Resumed H.C. Wainwright Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Sep-08-16 Reiterated H.C. Wainwright Buy
Aug-30-16 Upgrade Jefferies Hold → Buy
Aug-18-16 Initiated H.C. Wainwright Buy
Jun-28-16 Initiated Robert W. Baird Outperform
View All

Karyopharm Therapeutics Inc Stock (KPTI) Latest News

pulisher
05:07 AM

Karyopharm Therapeutics (NASDAQ:KPTI) Shares Pass Below 50-Day Moving AverageHere's What Happened - MarketBeat

05:07 AM
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Jan 26, 2026

Can Karyopharm Unlock Xpovio's Growth In 2026 With Pivotal Myelofibrosis Data Ahead? - RTTNews

Jan 26, 2026
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Jan 23, 2026

How New Price Targets Are Shaping The Story For Karyopharm Therapeutics (KPTI) - Yahoo Finance

Jan 23, 2026
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Jan 23, 2026

Abate, Karyopharm Therapeutics CAO, sells $1.6k in stock By Investing.com - Investing.com UK

Jan 23, 2026
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Jan 23, 2026

Abate, Karyopharm Therapeutics CAO, sells $1.6k in stock - Investing.com

Jan 23, 2026
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Jan 20, 2026

RBC Raises Price Target on Karyopharm Therapeutics to $23 From $19, Keeps Outperform Rating - marketscreener.com

Jan 20, 2026
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Jan 18, 2026

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Receives Consensus Recommendation of "Moderate Buy" from Brokerages - MarketBeat

Jan 18, 2026
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Jan 18, 2026

Aug Spikes: Can Karyopharm Therapeutics Inc disrupt its industryDividend Hike & Verified Entry Point Signals - baoquankhu1.vn

Jan 18, 2026
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Jan 16, 2026

Chart Watch: Will Karyopharm Therapeutics Inc outperform its industry peersJuly 2025 Intraday Action & Technical Pattern Alert System - baoquankhu1.vn

Jan 16, 2026
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Jan 13, 2026

Options Flow: Will Karyopharm Therapeutics Inc 25K0 stock rise with strong economyWeekly Risk Summary & Safe Entry Zone Tips - Bộ Nội Vụ

Jan 13, 2026
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Jan 13, 2026

Layoff Watch: What margin trends mean for Karyopharm Therapeutics Inc stockWeekly Stock Analysis & Accurate Intraday Trading Signals - Bộ Nội Vụ

Jan 13, 2026
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Jan 13, 2026

Analysts Are Bullish on Top Healthcare Stocks: Karyopharm Therapeutics (KPTI), Establishment Labs Holdings (ESTA) - The Globe and Mail

Jan 13, 2026
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Jan 13, 2026

Karyopharm expects phase 3 trial data in myelofibrosis by March - Investing.com Canada

Jan 13, 2026
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Jan 13, 2026

Karyopharm Therapeutics (NASDAQ:KPTI) Stock Crosses Above Fifty Day Moving AverageWhat's Next? - MarketBeat

Jan 13, 2026
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Jan 12, 2026

Karyopharm Issues Preliminary 2025 Financial Results and Outlook - TipRanks

Jan 12, 2026
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Jan 12, 2026

Karyopharm (KPTI) Anticipates Transformative 2026 with Key Trial Data - GuruFocus

Jan 12, 2026
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Jan 12, 2026

Karyopharm Therapeutics reports preliminary 2025 revenue of $145 mln - TradingView — Track All Markets

Jan 12, 2026
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Jan 12, 2026

Karyopharm Announces Preliminary Unaudited 2025 Revenue and Reiterates Expectation of Delivering Potentially Transformative Phase 3 Data in 2026 - marketscreener.com

Jan 12, 2026
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Jan 11, 2026

Karyopharm Therapeutics Inc.'s (NASDAQ:KPTI) Prospects Need A Boost To Lift Shares - simplywall.st

Jan 11, 2026
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Jan 10, 2026

Is Karyopharm Therapeutics Inc. stock attractive for passive investorsJuly 2025 EndofMonth & Low Drawdown Investment Ideas - ulpravda.ru

Jan 10, 2026
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Jan 09, 2026

Why Karyopharm Therapeutics Inc. (25K0) stock could rally stronglyQuarterly Growth Report & Verified Momentum Watchlists - Улправда

Jan 09, 2026
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Jan 09, 2026

Karyopharm (NASDAQ: KPTI) plans big share authorization increase to fund 2026 trials - Stock Titan

Jan 09, 2026
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Jan 08, 2026

Is Karyopharm Therapeutics Inc. stock supported by innovation pipelineEarnings Trend Report & Risk Controlled Swing Alerts - ulpravda.ru

Jan 08, 2026
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Jan 08, 2026

How Karyopharm Therapeutics Inc. stock performs in weak economy2025 Trade Ideas & AI Forecasted Entry and Exit Points - Улправда

Jan 08, 2026
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Jan 08, 2026

Will Karyopharm Therapeutics Inc. (25K0) stock rise with strong economyMarket Growth Summary & Scalable Portfolio Growth Ideas - Улправда

Jan 08, 2026
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Jan 08, 2026

Why Karyopharm Therapeutics Inc. stock attracts global investorsRate Hike & High Accuracy Investment Entry Signals - Улправда

Jan 08, 2026
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Jan 08, 2026

Is Karyopharm Therapeutics Inc. stock attractive for income investorsPortfolio Gains Report & Fast Momentum Entry Tips - Улправда

Jan 08, 2026
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Jan 08, 2026

Will Karyopharm Therapeutics Inc. stock remain a Wall Street favoriteTrend Reversal & Daily Chart Pattern Signals - Улправда

Jan 08, 2026
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Jan 02, 2026

Karyopharm Therapeutics reports inducement grants under Nasdaq Listing Rule 5635(c)(4) - MarketScreener

Jan 02, 2026
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Jan 02, 2026

Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(C)(4) - TradingView — Track All Markets

Jan 02, 2026
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Jan 02, 2026

Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - PR Newswire

Jan 02, 2026
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Dec 30, 2025

MACD Signal: Why Karyopharm Therapeutics Inc stock attracts global investors2025 Winners & Losers & Safe Capital Growth Tips - Bộ Nội Vụ

Dec 30, 2025
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Dec 24, 2025

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Given Consensus Rating of "Moderate Buy" by Analysts - MarketBeat

Dec 24, 2025
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Dec 22, 2025

KPTI (Karyopharm Therapeutics Inc) has impressive results - uspostnews.com

Dec 22, 2025
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Dec 22, 2025

Karyopharm Therapeutics (FRA:25K0) EV-to-OCF : -2.79 (As of Dec. 22, 2025) - GuruFocus

Dec 22, 2025
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Dec 21, 2025

Why Karyopharm Therapeutics Inc. (25K0) stock could be next leader2025 Earnings Impact & Growth Focused Investment Plans - Улправда

Dec 21, 2025
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Dec 20, 2025

Can Karyopharm Therapeutics Inc. stock resist sector downturnsJuly 2025 Market Mood & High Accuracy Trade Alerts - Улправда

Dec 20, 2025
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Dec 20, 2025

Is Karyopharm Therapeutics Inc. stock a bargain at current levelsIndustrial Stocks Review & Free Extraordinary Earning Power - bollywoodhelpline.com

Dec 20, 2025
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Dec 19, 2025

How Karyopharm Therapeutics Inc. stock responds to policy changesWeekly Trend Summary & Fast Entry Momentum Alerts - DonanımHaber

Dec 19, 2025
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Dec 19, 2025

Can Karyopharm Therapeutics Inc. stock withstand economic slowdownJuly 2025 Gainers & Precise Swing Trade Entry Alerts - DonanımHaber

Dec 19, 2025
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Dec 19, 2025

Will Karyopharm Therapeutics Inc. (25K0) stock beat international competitionQuarterly Portfolio Review & Accurate Entry/Exit Alerts - Улправда

Dec 19, 2025
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Dec 17, 2025

Piper Sandler names Karyopharm stock as 2026 top pick, maintains $12 target - Investing.com Canada

Dec 17, 2025
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Dec 12, 2025

Karyopharm Therapeutics’ Earnings Call: Progress Amid Challenges - MSN

Dec 12, 2025
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Dec 09, 2025

Karyopharm Therapeutics (NASDAQ:KPTI) Stock Price Passes Above 50-Day Moving AverageHere's What Happened - MarketBeat

Dec 09, 2025
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Dec 08, 2025

Karyopharm to Participate in Baird's Biotech Discovery Series - Karyopharm

Dec 08, 2025
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Dec 08, 2025

Karyopharm (Nasdaq: KPTI) to discuss myelofibrosis in Baird Biotech Discovery Series chat - Stock Titan

Dec 08, 2025
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Dec 07, 2025

Published on: 2025-12-10 09:05:07 - earlytimes.in

Dec 07, 2025

Karyopharm Therapeutics Inc Stock (KPTI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$99.82
price up icon 2.09%
$103.47
price up icon 0.87%
$34.40
price up icon 2.78%
$119.34
price up icon 1.14%
$162.64
price up icon 1.83%
biotechnology ONC
$336.16
price down icon 0.48%
Cap:     |  Volume (24h):