5.75
price down icon2.38%   -0.14
after-market After Hours: 5.75
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Karyopharm Therapeutics Inc stock is traded at $5.75, with a volume of 64,488. It is down -2.38% in the last 24 hours and up +7.28% over the past month. Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company pioneering novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company derives its revenue from United States.
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Previous Close:
$5.89
Open:
$5.95
24h Volume:
64,488
Relative Volume:
0.38
Market Cap:
$98.04M
Revenue:
$137.27M
Net Income/Loss:
$-123.57M
P/E Ratio:
-0.522
EPS:
-11.016
Net Cash Flow:
$-102.89M
1W Performance:
+2.31%
1M Performance:
+7.28%
6M Performance:
+34.98%
1Y Performance:
-51.87%
1-Day Range:
Value
$5.74
$5.95
1-Week Range:
Value
$5.30
$6.15
52-Week Range:
Value
$3.51
$12.45

Karyopharm Therapeutics Inc Stock (KPTI) Company Profile

Name
Name
Karyopharm Therapeutics Inc
Name
Phone
617-658-0600
Name
Address
85 WELLS AVENUE, NEWTON, MA
Name
Employee
279
Name
Twitter
@Karyopharm
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
KPTI's Discussions on Twitter

Compare KPTI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
KPTI
Karyopharm Therapeutics Inc
5.75 100.77M 137.27M -123.57M -102.89M -11.02
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
455.48 116.04B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
718.36 75.97B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
458.12 61.48B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
901.17 56.40B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
204.00 43.73B 447.02M -1.18B -906.14M -6.1812

Karyopharm Therapeutics Inc Stock (KPTI) Upgrades & Downgrades

Date Action Analyst Rating Change
Oct-13-25 Upgrade H.C. Wainwright Neutral → Buy
Jul-16-25 Downgrade H.C. Wainwright Buy → Neutral
Jul-11-25 Resumed H.C. Wainwright Buy
Jan-19-23 Initiated Piper Sandler Overweight
Nov-04-22 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-09-22 Upgrade JP Morgan Underweight → Neutral
Nov-19-21 Resumed Morgan Stanley Equal-Weight
Aug-06-21 Downgrade JP Morgan Overweight → Neutral
Aug-06-21 Downgrade RBC Capital Mkts Outperform → Sector Perform
Aug-06-21 Downgrade SVB Leerink Outperform → Mkt Perform
Jul-02-20 Initiated Morgan Stanley Overweight
Mar-04-20 Initiated Barclays Overweight
Jan-17-20 Downgrade Wedbush Outperform → Neutral
Jul-23-19 Upgrade JP Morgan Neutral → Overweight
Jul-05-19 Reiterated H.C. Wainwright Buy
Jul-05-19 Reiterated Robert W. Baird Outperform
Mar-01-19 Downgrade JP Morgan Overweight → Neutral
Feb-28-19 Reiterated BofA/Merrill Underperform
Feb-27-19 Downgrade BofA/Merrill Neutral → Underperform
Jan-03-19 Upgrade BofA/Merrill Underperform → Neutral
Dec-03-18 Initiated B. Riley FBR Buy
Nov-09-18 Upgrade Wedbush Neutral → Outperform
May-24-18 Downgrade Wedbush Outperform → Neutral
Apr-02-18 Resumed Leerink Partners Outperform
Nov-15-17 Resumed H.C. Wainwright Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Sep-08-16 Reiterated H.C. Wainwright Buy
Aug-30-16 Upgrade Jefferies Hold → Buy
Aug-18-16 Initiated H.C. Wainwright Buy
Jun-28-16 Initiated Robert W. Baird Outperform
View All

Karyopharm Therapeutics Inc Stock (KPTI) Latest News

pulisher
03:16 AM

Is Karyopharm Therapeutics Inc. (25K0) stock among top earnings plays2025 Technical Overview & Safe Capital Growth Tips - Newser

03:16 AM
pulisher
Dec 04, 2025

How Karyopharm Therapeutics Inc. (25K0) stock reacts to new regulationsTrade Volume Summary & Daily Stock Trend Watchlist - Newser

Dec 04, 2025
pulisher
Dec 04, 2025

What makes Karyopharm Therapeutics Inc. (25K0) stock appealing to growth investorsJuly 2025 Volume & Fast Exit and Entry Strategy Plans - Newser

Dec 04, 2025
pulisher
Dec 03, 2025

Will Karyopharm Therapeutics Inc. (25K0) stock outperform global peersJuly 2025 PostEarnings & Real-Time Buy Zone Alerts - Newser

Dec 03, 2025
pulisher
Dec 03, 2025

Will Karyopharm Therapeutics Inc. (25K0) stock split increase liquidity2025 Big Picture & Fast Gaining Stock Reports - Newser

Dec 03, 2025
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Dec 03, 2025

Will Karyopharm Therapeutics Inc. (25K0) stock announce special dividendMarket Growth Summary & Expert Curated Trade Ideas - Newser

Dec 03, 2025
pulisher
Dec 03, 2025

Why global investors buy Karyopharm Therapeutics Inc. (25K0) stockJuly 2025 Highlights & AI Based Buy/Sell Signal Reports - Newser

Dec 03, 2025
pulisher
Dec 01, 2025

Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - Karyopharm

Dec 01, 2025
pulisher
Dec 01, 2025

Karyopharm (Nasdaq: KPTI) plans fireside chat at Piper Sandler 37th Healthcare Conference - Stock Titan

Dec 01, 2025
pulisher
Dec 01, 2025

Karyopharm to Participate at the Piper Sandler 37th Annual Healthcare Conference - Karyopharm

Dec 01, 2025
pulisher
Nov 30, 2025

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Given Consensus Rating of "Moderate Buy" by Brokerages - MarketBeat

Nov 30, 2025
pulisher
Nov 28, 2025

Looking at the Narrative for Karyopharm as Financing and Trial Milestones Shift the Outlook - Yahoo Finance

Nov 28, 2025
pulisher
Nov 28, 2025

Karyopharm Grows Revenue With Strong XPOVIO Sales And Partnerships - Finimize

Nov 28, 2025
pulisher
Nov 27, 2025

Karyopharm Therapeutics (NASDAQ:KPTI) Stock Price Passes Below 200 Day Moving AverageWhat's Next? - MarketBeat

Nov 27, 2025
pulisher
Nov 25, 2025

Karyopharm Therapeutics (KPTI) Price Target Decreased by 11.70% to 14.11 - MSN

Nov 25, 2025
pulisher
Nov 24, 2025

[424B3] Karyopharm Therapeutics Inc. Prospectus Filed Pursuant to Rule 424(b)(3) - Stock Titan

Nov 24, 2025
pulisher
Nov 21, 2025

Is Karyopharm Therapeutics Inc. stock vulnerable to regulatory risks2025 Analyst Calls & Low Volatility Stock Suggestions - newser.com

Nov 21, 2025
pulisher
Nov 21, 2025

Why Karyopharm Therapeutics Inc. (25K0) stock trades below fair valueJuly 2025 Opening Moves & Detailed Earnings Play Strategies - newser.com

Nov 21, 2025
pulisher
Nov 21, 2025

How Karyopharm Therapeutics Inc. stock reacts to job market dataStock Surge & AI Driven Price Predictions - newser.com

Nov 21, 2025
pulisher
Nov 21, 2025

Is Karyopharm Therapeutics Inc. (25K0) stock undervalued by metrics2025 Investor Takeaways & Daily Stock Trend Watchlist - newser.com

Nov 21, 2025
pulisher
Nov 21, 2025

What momentum indicators show for Karyopharm Therapeutics Inc. stockJuly 2025 Reactions & Consistent Income Trade Recommendations - newser.com

Nov 21, 2025
pulisher
Nov 21, 2025

Why pension funds invest in Karyopharm Therapeutics Inc. (25K0) stockRate Cut & Technical Pattern Recognition Alerts - newser.com

Nov 21, 2025
pulisher
Nov 20, 2025

Can Karyopharm Therapeutics Inc. stock hit record highs againGold Moves & AI Driven Stock Movement Reports - newser.com

Nov 20, 2025
pulisher
Nov 20, 2025

Is Karyopharm Therapeutics Inc. stock attractive for long term wealth building2025 Short Interest & Consistent Profit Alerts - newser.com

Nov 20, 2025
pulisher
Nov 19, 2025

Can Karyopharm Therapeutics Inc. (25K0) stock sustain revenue momentumMarket Weekly Review & Intraday High Probability Setup Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

What’s the recovery path for long term holders of Karyopharm Therapeutics Inc.July 2025 Snapshot & Advanced Swing Trade Entry Plans - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Will Karyopharm Therapeutics Inc. (25K0) stock outperform energy sector in 2025Weekly Trade Report & Weekly Breakout Opportunity Watchlist - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Is Karyopharm Therapeutics Inc. (25K0) stock a top hedge fund pickQuarterly Portfolio Review & Low Risk High Win Rate Picks - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Quantitative breakdown of Karyopharm Therapeutics Inc. recent moveMarket Performance Report & Real-Time Market Sentiment Alerts - newser.com

Nov 19, 2025

Karyopharm Therapeutics Inc Stock (KPTI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$39.73
price up icon 1.44%
$31.74
price down icon 0.91%
$102.52
price up icon 2.03%
$96.25
price up icon 0.27%
biotechnology ONC
$322.90
price down icon 2.53%
$204.00
price down icon 0.51%
Cap:     |  Volume (24h):