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Karyopharm Therapeutics Inc stock is traded at $4.39, with a volume of 33,104. It is up +0.69% in the last 24 hours and down -10.77% over the past month. Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company pioneering novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company derives its revenue from United States.
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Previous Close:
$4.36
Open:
$4.22
24h Volume:
33,104
Relative Volume:
0.30
Market Cap:
$38.79M
Revenue:
$140.46M
Net Income/Loss:
$-146.34M
P/E Ratio:
-3.4567
EPS:
-1.27
Net Cash Flow:
$-117.73M
1W Performance:
-2.23%
1M Performance:
-10.77%
6M Performance:
-58.19%
1Y Performance:
-71.31%
1-Day Range:
Value
$4.22
$4.53
1-Week Range:
Value
$4.19
$4.62
52-Week Range:
Value
$3.51
$17.40

Karyopharm Therapeutics Inc Stock (KPTI) Company Profile

Name
Name
Karyopharm Therapeutics Inc
Name
Phone
617-658-0600
Name
Address
85 WELLS AVENUE, NEWTON, MA
Name
Employee
279
Name
Twitter
@Karyopharm
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
KPTI's Discussions on Twitter

Compare KPTI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
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KPTI
Karyopharm Therapeutics Inc
4.39 38.79M 140.46M -146.34M -117.73M -1.27
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VRTX
Vertex Pharmaceuticals Inc
455.45 115.69B 11.10B -988.90M -1.26B -3.92
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REGN
Regeneron Pharmaceuticals Inc
529.24 53.25B 14.09B 4.50B 2.96B 39.28
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ALNY
Alnylam Pharmaceuticals Inc
307.99 39.22B 2.35B -269.70M -75.39M -2.09
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ARGX
Argen X Se Adr
577.89 35.78B 2.58B 1.06B -1.28B 16.33
Biotechnology icon
ONC
Beone Medicines Ltd Adr
269.63 27.68B 3.81B -644.79M -669.77M -6.24

Karyopharm Therapeutics Inc Stock (KPTI) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-19-23 Initiated Piper Sandler Overweight
Nov-04-22 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-09-22 Upgrade JP Morgan Underweight → Neutral
Nov-19-21 Resumed Morgan Stanley Equal-Weight
Aug-06-21 Downgrade JP Morgan Overweight → Neutral
Aug-06-21 Downgrade RBC Capital Mkts Outperform → Sector Perform
Aug-06-21 Downgrade SVB Leerink Outperform → Mkt Perform
Jul-02-20 Initiated Morgan Stanley Overweight
Mar-04-20 Initiated Barclays Overweight
Jan-17-20 Downgrade Wedbush Outperform → Neutral
Jul-23-19 Upgrade JP Morgan Neutral → Overweight
Jul-05-19 Reiterated H.C. Wainwright Buy
Jul-05-19 Reiterated Robert W. Baird Outperform
Mar-01-19 Downgrade JP Morgan Overweight → Neutral
Feb-28-19 Reiterated BofA/Merrill Underperform
Feb-27-19 Downgrade BofA/Merrill Neutral → Underperform
Jan-03-19 Upgrade BofA/Merrill Underperform → Neutral
Dec-03-18 Initiated B. Riley FBR Buy
Nov-09-18 Upgrade Wedbush Neutral → Outperform
May-24-18 Downgrade Wedbush Outperform → Neutral
Apr-02-18 Resumed Leerink Partners Outperform
Nov-15-17 Resumed H.C. Wainwright Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Sep-08-16 Reiterated H.C. Wainwright Buy
Aug-30-16 Upgrade Jefferies Hold → Buy
Aug-18-16 Initiated H.C. Wainwright Buy
Jun-28-16 Initiated Robert W. Baird Outperform
View All

Karyopharm Therapeutics Inc Stock (KPTI) Latest News

pulisher
03:27 AM

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Shares Acquired by Two Sigma Investments LP - Defense World

03:27 AM
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Jun 10, 2025

Class Action ReminderNFLX, KPTI & MNKBronstein, Gewirtz & Grossman, LLC - ACCESS Newswire

Jun 10, 2025
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Jun 09, 2025

Two Sigma Advisers LP Buys 45,400 Shares of Karyopharm Therapeutics Inc. (NASDAQ:KPTI) - Defense World

Jun 09, 2025
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Jun 07, 2025

Millennium Management LLC Lowers Stock Position in Karyopharm Therapeutics Inc. (NASDAQ:KPTI) - Defense World

Jun 07, 2025
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Jun 05, 2025

Karyopharm at Jefferies: Pioneering Trials in Cancer Treatment By Investing.com - Investing.com Nigeria

Jun 05, 2025
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Jun 05, 2025

Karyopharm at Jefferies: Pioneering Trials in Cancer Treatment - Investing.com

Jun 05, 2025
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Jun 04, 2025

Karyopharm to Present at the Jefferies Global Healthcare Conference - Kilgore News Herald

Jun 04, 2025
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Jun 03, 2025

Karyopharm to Present at the Jefferies Global Healthcare Conference | KPTI Stock News - GuruFocus

Jun 03, 2025
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Jun 03, 2025

Northern Trust Corp Acquires 54,061 Shares of Karyopharm Therapeutics Inc. (NASDAQ:KPTI) - Defense World

Jun 03, 2025
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Jun 02, 2025

Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule - marketscreener.com

Jun 02, 2025
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Jun 02, 2025

Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) | KPTI Stock News - GuruFocus

Jun 02, 2025
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Jun 02, 2025

Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - PR Newswire

Jun 02, 2025
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May 30, 2025

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Shares Acquired by Jane Street Group LLC - Defense World

May 30, 2025
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May 29, 2025

Karyopharm increases share reserve for equity plan - Investing.com India

May 29, 2025
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May 29, 2025

Karyopharm Therapeutics Stockholders Approve Equity Plan Amendment - TipRanks

May 29, 2025
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May 29, 2025

Karyopharm increases share reserve for equity plan By Investing.com - Investing.com UK

May 29, 2025
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May 29, 2025

D. E. Shaw & Co. Inc. Sells 817,711 Shares of Karyopharm Therapeutics Inc. (NASDAQ:KPTI) - Defense World

May 29, 2025
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May 28, 2025

Hepatic Impairment Market Predicted to See Upsurge Through 2032, Highlights DelveInsight | Novartis, ApoPharma, Indivior Inc., Boehringer Ingelheim, Ocera Therapeutics, Orient Europharma, Karyopharm - Barchart.com

May 28, 2025
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May 27, 2025

Focus Partners Wealth Makes New Investment in Karyopharm Therapeutics Inc. (NASDAQ:KPTI) - Defense World

May 27, 2025
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May 26, 2025

Here's Why Karyopharm Therapeutics (KPTI) Is a Great 'Buy the Bottom' Stock Now - Yahoo Finance

May 26, 2025
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May 25, 2025

Karyopharm Therapeutics’ SWOT analysis: oncology firm’s stock faces pivotal year - Investing.com India

May 25, 2025
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May 24, 2025

Investors Don't See Light At End Of Karyopharm Therapeutics Inc.'s (NASDAQ:KPTI) Tunnel And Push Stock Down 27% - simplywall.st

May 24, 2025
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May 22, 2025

Here's Why Shareholders May Want To Be Cautious With Increasing Karyopharm Therapeutics Inc.'s (NASDAQ:KPTI) CEO Pay Packet - simplywall.st

May 22, 2025
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May 21, 2025

Karyopharm at RBC Capital Markets: Strategic Insights on XPOVIO and Pipeline - Investing.com Australia

May 21, 2025
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May 20, 2025

Karyopharm to Participate at the 2025 RBC Capital Markets Global Healthcare Conference - Eastern Progress

May 20, 2025
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May 19, 2025

Does Karyopharm Therapeutics (KPTI) Have the Potential to Rally 521.62% as Wall Street Analysts Expect? - sharewise

May 19, 2025
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May 19, 2025

Karyopharm to Participate at the 2025 RBC Capital Markets Global Healthcare Conference | KPTI Stock News - GuruFocus

May 19, 2025
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May 16, 2025

StockNews.com Downgrades Karyopharm Therapeutics (NASDAQ:KPTI) to Sell - Defense World

May 16, 2025
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May 16, 2025

Leerink Partnrs Issues Positive Estimate for KPTI Earnings - Defense World

May 16, 2025
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May 16, 2025

Brokerages Set Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Price Target at $45.60 - Defense World

May 16, 2025
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May 16, 2025

Karyopharm targets $1B peak U.S. revenue in myelofibrosis as Phase 3 SENTRY enrollment nears completion - MSN

May 16, 2025
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May 15, 2025

Karyopharm’s Earnings Call: Clinical Gains Amid Financial Strains - TipRanks

May 15, 2025
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May 15, 2025

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Q1 2025 Earnings Call Transcript - Insider Monkey

May 15, 2025
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May 15, 2025

Robert W. Baird Issues Pessimistic Forecast for Karyopharm Therapeutics (NASDAQ:KPTI) Stock Price - Defense World

May 15, 2025
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May 15, 2025

Karyopharm Announces Poster Presentation on Selinexor in Myelofi - GuruFocus

May 15, 2025
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May 14, 2025

KPTI to Present Promising Selinexor Data at Upcoming Hematology Meeting | KPTI Stock News - GuruFocus

May 14, 2025
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May 14, 2025

Karyopharm abstract selected for presentation at 2025 EHA meeting - TipRanks

May 14, 2025
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May 14, 2025

Karyopharm Announces Poster Presentation on Selinexor in Myelofibrosis at the 2025 European Hematology Association Annual Meeting - PR Newswire

May 14, 2025
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May 13, 2025

KPTI: RBC Capital Lowers Price Target while Maintaining Outperform Rating | KPTI Stock News - GuruFocus

May 13, 2025
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May 13, 2025

RBC Capital cuts Karyopharm stock price target to $33 By Investing.com - Investing.com Canada

May 13, 2025
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May 13, 2025

KPTI: RBC Capital Lowers Price Target while Maintaining Outperfo - GuruFocus

May 13, 2025
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May 13, 2025

These Analysts Revise Their Forecasts On Karyopharm Therapeutics After Q1 Results - Benzinga

May 13, 2025
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May 13, 2025

KPTI Misses Q1 Revenue Estimates but Advances Myelofibrosis Tria - GuruFocus

May 13, 2025
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May 13, 2025

KPTI Stock Boosted as Barclays Raises Price Target to $10 | KPTI - GuruFocus

May 13, 2025
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May 13, 2025

Karyopharm (KPTI) Target Price Reduced by RBC Capital | KPTI Sto - GuruFocus

May 13, 2025
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May 13, 2025

KPTI: Baird Lowers Price Target but Maintains Outperform Rating - GuruFocus

May 13, 2025
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May 13, 2025

Karyopharm (KPTI) Price Target Reduced by Baird, Outperform Rati - GuruFocus

May 13, 2025
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May 13, 2025

Karyopharm Therapeutics Inc Reports Q1 2025 Earnings: EPS Loss o - GuruFocus

May 13, 2025
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May 13, 2025

RBC Adjusts Price Target on Karyopharm Therapeutics to $33 From $43, Maintains Outperform Rating - marketscreener.com

May 13, 2025
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May 13, 2025

Barclays Updates Karyopharm (KPTI) Price Target, Eyes Future Dat - GuruFocus

May 13, 2025

Karyopharm Therapeutics Inc Stock (KPTI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$98.73
price up icon 1.91%
$22.82
price down icon 1.17%
$34.84
price down icon 1.22%
$19.78
price down icon 1.88%
$106.57
price up icon 1.57%
biotechnology ONC
$269.63
price down icon 2.50%
Cap:     |  Volume (24h):