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Denali Therapeutics Inc stock is traded at $17.98, with a volume of 1.35M. It is up +3.51% in the last 24 hours and up +2.63% over the past month. Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegeneration disease. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, DNL747, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others.
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Previous Close:
$17.37
Open:
$17.41
24h Volume:
1.35M
Relative Volume:
0.76
Market Cap:
$2.64B
Revenue:
$340.81M
Net Income/Loss:
$-419.65M
P/E Ratio:
-6.3088
EPS:
-2.85
Net Cash Flow:
$-402.10M
1W Performance:
-9.92%
1M Performance:
+2.63%
6M Performance:
+20.47%
1Y Performance:
-23.39%
1-Day Range:
Value
$17.24
$18.30
1-Week Range:
Value
$17.20
$20.57
52-Week Range:
Value
$10.57
$24.34

Denali Therapeutics Inc Stock (DNLI) Company Profile

Name
Name
Denali Therapeutics Inc
Name
Phone
(650) 866-8547
Name
Address
161 OYSTER POINT BLVD., SOUTH SAN FRANCISCO
Name
Employee
517
Name
Twitter
Name
Next Earnings Date
2025-08-08
Name
Latest SEC Filings
Name
DNLI's Discussions on Twitter

Compare DNLI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
DNLI
Denali Therapeutics Inc
17.98 2.55B 340.81M -419.65M -402.10M -2.85
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
452.04 113.14B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
741.29 78.49B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
877.94 54.76B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
397.55 54.51B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
INSM
Insmed Inc
197.01 41.64B 447.02M -1.18B -906.14M -6.1812

Denali Therapeutics Inc Stock (DNLI) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-10-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Mar-07-25 Resumed Morgan Stanley Overweight
Feb-11-25 Initiated Deutsche Bank Buy
Jan-07-25 Initiated Robert W. Baird Outperform
Jan-03-25 Initiated William Blair Outperform
Dec-16-24 Upgrade Stifel Hold → Buy
Oct-10-24 Resumed Raymond James Mkt Perform
Oct-07-24 Downgrade Cantor Fitzgerald Overweight → Neutral
Dec-13-23 Initiated Citigroup Buy
Nov-20-23 Resumed JP Morgan Overweight
Oct-24-23 Resumed Cantor Fitzgerald Overweight
Sep-06-23 Initiated B. Riley Securities Buy
Jan-30-23 Initiated SVB Securities Outperform
Dec-05-22 Initiated Cowen Outperform
Nov-02-22 Upgrade BTIG Research Neutral → Buy
Nov-02-22 Initiated BofA Securities Buy
Jun-23-22 Initiated Berenberg Buy
Dec-10-21 Resumed Raymond James Mkt Perform
Sep-21-21 Initiated Oppenheimer Outperform
Sep-01-21 Initiated SMBC Nikko Outperform
May-18-21 Initiated UBS Buy
Feb-26-21 Reiterated H.C. Wainwright Buy
Feb-10-21 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-11-20 Reiterated H.C. Wainwright Buy
Oct-16-20 Downgrade BTIG Research Buy → Neutral
Sep-14-20 Resumed JP Morgan Overweight
Aug-20-20 Reiterated H.C. Wainwright Buy
Mar-13-20 Upgrade Evercore ISI In-line → Outperform
Feb-28-20 Upgrade Wedbush Neutral → Outperform
Feb-24-20 Initiated Jefferies Buy
Feb-19-20 Initiated Stifel Hold
Jan-27-20 Upgrade Goldman Neutral → Buy
Sep-26-19 Initiated Wedbush Neutral
Sep-13-19 Initiated Nomura Buy
Aug-09-19 Initiated BTIG Research Buy
Jun-26-19 Initiated H.C. Wainwright Buy
Nov-15-18 Initiated Cantor Fitzgerald Overweight
Nov-12-18 Initiated Janney Buy
Mar-12-18 Downgrade Evercore ISI Outperform → In-line
Jan-02-18 Initiated Evercore ISI Outperform
Jan-02-18 Initiated Goldman Neutral
Jan-02-18 Initiated JP Morgan Overweight
Jan-02-18 Initiated Morgan Stanley Overweight
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Denali Therapeutics Inc Stock (DNLI) Latest News

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Dec 12, 2025

Will Denali's Expanding Pipeline Deliver Breakthroughs In Neurodegenerative Medicine? - RTTNews

Dec 12, 2025
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Dec 11, 2025

Wedbush Maintains 'Outperform' Rating for DNLI, Lowers Price Tar - GuruFocus

Dec 11, 2025
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Dec 11, 2025

Denali Therapeutics announces $200M proposed offering of common stock and pre-funded warrants - MSN

Dec 11, 2025
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Dec 11, 2025

Denali Therapeutics dips after pricing $200M equity offering - MSN

Dec 11, 2025
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Dec 10, 2025

Denali Therapeutics prices stock offering at $17.50 per share - MSN

Dec 10, 2025
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Dec 10, 2025

Denali: Maintaining Strong Buy Based On DNL126 Expansion As MPS IIIA Treatment (DNLI) - Seeking Alpha

Dec 10, 2025
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Dec 10, 2025

Denali Therapeutics (NASDAQ:DNLI) Shares Gap DownHere's What Happened - MarketBeat

Dec 10, 2025
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Dec 10, 2025

Denali Therapeutics Prices $200 Million Public Offering - marketscreener.com

Dec 10, 2025
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Dec 10, 2025

Denali Therapeutics Announces Proposed Offering of Common Stock and Pre-Funded Warrants - Sahm

Dec 10, 2025
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Dec 10, 2025

Denali Therapeutics prices $200 million public offering By Investing.com - Investing.com India

Dec 10, 2025
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Dec 10, 2025

Denali Therapeutics prices $200 million public offering - Investing.com

Dec 10, 2025
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Dec 10, 2025

Denali Therapeutics says co prices public offering of 9.14 mln shares at $17.50 each - marketscreener.com

Dec 10, 2025
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Dec 10, 2025

Denali Therapeutics Announces Pricing of Public Offering of Common Stock and Pre-Funded Warrants - GlobeNewswire

Dec 10, 2025
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Dec 10, 2025

Denali Therapeutics (NASDAQ: DNLI) prices $200M equity deal at $17.50 - Stock Titan

Dec 10, 2025
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Dec 09, 2025

Denali Therapeutics slides after launching $200 million share sale - TradingView — Track All Markets

Dec 09, 2025
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Dec 09, 2025

Denali Therapeutics Plans $200 Million Public Offering - marketscreener.com

Dec 09, 2025
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Dec 09, 2025

Denali Therapeutics stock falls after announcing $200 million public offering By Investing.com - Investing.com Australia

Dec 09, 2025
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Dec 09, 2025

Denali Therapeutics stock falls after announcing $200 million public offering - Investing.com

Dec 09, 2025
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Dec 09, 2025

Denali Therapeutics announces $200 million public offering By Investing.com - Investing.com India

Dec 09, 2025
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Dec 09, 2025

Denali Therapeutics announces $200 million public offering - Investing.com

Dec 09, 2025
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Dec 09, 2025

Denali Therapeutics Inc. Announces $200 Million Public Offering of Common Stock and Pre-Funded Warrants - Quiver Quantitative

Dec 09, 2025
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Dec 09, 2025

Denali Therapeutics (NASDAQ: DNLI) plans $200M stock, pre-funded warrant sale with $30M option - Stock Titan

Dec 09, 2025
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Dec 09, 2025

Marshall Wace LLP Sells 783,172 Shares of Denali Therapeutics Inc. $DNLI - MarketBeat

Dec 09, 2025
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Dec 08, 2025

Technical Reactions to DNLI Trends in Macro Strategies - news.stocktradersdaily.com

Dec 08, 2025
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Dec 07, 2025

Denali enters into a $275M funding deal with Royalty Pharma - MSN

Dec 07, 2025
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Dec 07, 2025

Denali clinches $275 million royalty deal to power potential breakthrough Hunter Syndrome therapy - Indian Pharma Post

Dec 07, 2025
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Dec 07, 2025

Denali Therapeutics (DNLI): Rethinking Valuation After a 33% One-Month Share Price Rebound - Yahoo Finance

Dec 07, 2025
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Dec 06, 2025

Denali’s Royalty Deal to Fund Hunter Syndrome Drug Could Be A Game Changer For Denali Therapeutics (DNLI) - Yahoo Finance

Dec 06, 2025
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Dec 06, 2025

BTIG Research Reiterates Buy Rating for Denali Therapeutics (NASDAQ:DNLI) - MarketBeat

Dec 06, 2025
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Dec 06, 2025

3,947,387 Shares in Denali Therapeutics Inc. $DNLI Acquired by Norges Bank - MarketBeat

Dec 06, 2025
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Dec 05, 2025

Denali Therapeutics stock maintains Buy rating at Stifel ahead of 2026 launch By Investing.com - Investing.com South Africa

Dec 05, 2025
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Dec 05, 2025

Denali Therapeutics (MUN:4DN) Price Target Decreased by 15.88% to 28.11 - Nasdaq

Dec 05, 2025
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Dec 05, 2025

What's Going On With Denali Therapeutics Stock Friday?Denali Therapeutics (NASDAQ:DNLI) - Benzinga

Dec 05, 2025
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Dec 05, 2025

Denali Enters Into a $275M Funding Deal With Royalty Pharma - Finviz

Dec 05, 2025
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Dec 05, 2025

Denali Therapeutics stock maintains Buy rating at Stifel ahead of 2026 launch - Investing.com Nigeria

Dec 05, 2025
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Dec 05, 2025

Wedbush Adjusts Denali Therapeutics Price Target to $31 From $30, Maintains Outperform Rating - marketscreener.com

Dec 05, 2025
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Dec 05, 2025

FDA Pauses Denali’s Pompe Plans Due to Preclinical Safety Signals - BioSpace

Dec 05, 2025
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Dec 05, 2025

BTIG Reiterates Denali Therapeutics (DNLI) Buy Recommendation - Nasdaq

Dec 05, 2025
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Dec 05, 2025

William Blair Maintains Denali Therapeutics(DNLI.US) With Buy Rating - 富途牛牛

Dec 05, 2025
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Dec 05, 2025

Schroder Investment Management Group Purchases 94,744 Shares of Denali Therapeutics Inc. $DNLI - MarketBeat

Dec 05, 2025
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Dec 04, 2025

Denali Therapeutics stock rises on $275 million royalty deal with Royalty Pharma - Investing.com Australia

Dec 04, 2025
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Dec 04, 2025

Transcript : Denali Therapeutics Inc.Analyst/Investor Day - MarketScreener

Dec 04, 2025
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Dec 04, 2025

Denali Therapeutics and Royalty Pharma announce $275 million royalty funding agreement - marketscreener.com

Dec 04, 2025
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Dec 04, 2025

Denali Therapeutics And Royalty Pharma Announce $275 Million Royalty Funding Agreement - TradingView

Dec 04, 2025
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Dec 04, 2025

Denali Therapeutics and Royalty Pharma ink $275 million funding deal By Investing.com - Investing.com Nigeria

Dec 04, 2025
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Dec 04, 2025

Denali Therapeutics and Royalty Pharma ink $275 million funding deal - Investing.com

Dec 04, 2025
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Dec 04, 2025

Denali Therapeutics enters $275 million royalty funding agreement with Royalty Pharma - Investing.com

Dec 04, 2025
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Dec 04, 2025

Denali Therapeutics secures $275M royalty funding deal - MSN

Dec 04, 2025
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Dec 04, 2025

Denali Therapeutics Secures $275M Royalty Funding Deal - TipRanks

Dec 04, 2025
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Dec 04, 2025

Royalty Pharma and Denali Therapeutics Announce $275 Million Royalty Agreement for Tividenofusp Alfa Development - Quiver Quantitative

Dec 04, 2025
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Dec 04, 2025

Royalty Pharma and Denali Therapeutics Announce $275 Million Royalty Funding Agreement - The Manila Times

Dec 04, 2025

Denali Therapeutics Inc Stock (DNLI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$38.39
price down icon 1.08%
$95.41
price down icon 0.72%
$31.31
price down icon 3.07%
$94.81
price down icon 1.24%
biotechnology ONC
$319.06
price down icon 0.55%
$197.01
price up icon 0.91%
Cap:     |  Volume (24h):