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Denali Therapeutics Inc stock is traded at $18.00, with a volume of 1.44M. It is up +4.90% in the last 24 hours and up +6.13% over the past month. Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegeneration disease. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, DNL747, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others.
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Previous Close:
$17.16
Open:
$16.93
24h Volume:
1.44M
Relative Volume:
0.78
Market Cap:
$2.64B
Revenue:
$340.81M
Net Income/Loss:
$-419.65M
P/E Ratio:
-6.3158
EPS:
-2.85
Net Cash Flow:
$-402.10M
1W Performance:
+3.21%
1M Performance:
+6.13%
6M Performance:
+31.48%
1Y Performance:
-25.68%
1-Day Range:
Value
$16.87
$18.23
1-Week Range:
Value
$16.85
$18.23
52-Week Range:
Value
$10.57
$26.18

Denali Therapeutics Inc Stock (DNLI) Company Profile

Name
Name
Denali Therapeutics Inc
Name
Phone
(650) 866-8547
Name
Address
161 OYSTER POINT BLVD., SOUTH SAN FRANCISCO
Name
Employee
517
Name
Twitter
Name
Next Earnings Date
2025-08-08
Name
Latest SEC Filings
Name
DNLI's Discussions on Twitter

Compare DNLI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
DNLI
Denali Therapeutics Inc
18.00 2.52B 340.81M -419.65M -402.10M -2.85
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
426.76 107.15B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
755.90 77.46B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
436.38 58.90B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
918.92 56.55B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
198.76 42.58B 447.02M -1.18B -906.14M -6.1812

Denali Therapeutics Inc Stock (DNLI) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-10-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Mar-07-25 Resumed Morgan Stanley Overweight
Feb-11-25 Initiated Deutsche Bank Buy
Jan-07-25 Initiated Robert W. Baird Outperform
Jan-03-25 Initiated William Blair Outperform
Dec-16-24 Upgrade Stifel Hold → Buy
Oct-10-24 Resumed Raymond James Mkt Perform
Oct-07-24 Downgrade Cantor Fitzgerald Overweight → Neutral
Dec-13-23 Initiated Citigroup Buy
Nov-20-23 Resumed JP Morgan Overweight
Oct-24-23 Resumed Cantor Fitzgerald Overweight
Sep-06-23 Initiated B. Riley Securities Buy
Jan-30-23 Initiated SVB Securities Outperform
Dec-05-22 Initiated Cowen Outperform
Nov-02-22 Upgrade BTIG Research Neutral → Buy
Nov-02-22 Initiated BofA Securities Buy
Jun-23-22 Initiated Berenberg Buy
Dec-10-21 Resumed Raymond James Mkt Perform
Sep-21-21 Initiated Oppenheimer Outperform
Sep-01-21 Initiated SMBC Nikko Outperform
May-18-21 Initiated UBS Buy
Feb-26-21 Reiterated H.C. Wainwright Buy
Feb-10-21 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-11-20 Reiterated H.C. Wainwright Buy
Oct-16-20 Downgrade BTIG Research Buy → Neutral
Sep-14-20 Resumed JP Morgan Overweight
Aug-20-20 Reiterated H.C. Wainwright Buy
Mar-13-20 Upgrade Evercore ISI In-line → Outperform
Feb-28-20 Upgrade Wedbush Neutral → Outperform
Feb-24-20 Initiated Jefferies Buy
Feb-19-20 Initiated Stifel Hold
Jan-27-20 Upgrade Goldman Neutral → Buy
Sep-26-19 Initiated Wedbush Neutral
Sep-13-19 Initiated Nomura Buy
Aug-09-19 Initiated BTIG Research Buy
Jun-26-19 Initiated H.C. Wainwright Buy
Nov-15-18 Initiated Cantor Fitzgerald Overweight
Nov-12-18 Initiated Janney Buy
Mar-12-18 Downgrade Evercore ISI Outperform → In-line
Jan-02-18 Initiated Evercore ISI Outperform
Jan-02-18 Initiated Goldman Neutral
Jan-02-18 Initiated JP Morgan Overweight
Jan-02-18 Initiated Morgan Stanley Overweight
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Denali Therapeutics Inc Stock (DNLI) Latest News

pulisher
Nov 22, 2025

Transcript : Denali Therapeutics Inc. Presents at Jefferies London Healthcare Conference 2025, Nov-18-2025 12 - MarketScreener

Nov 22, 2025
pulisher
Nov 21, 2025

How Denali Therapeutics Inc. stock trades during market volatility2025 Volatility Report & Reliable Trade Execution Plans - newser.com

Nov 21, 2025
pulisher
Nov 21, 2025

How risky is Denali Therapeutics Inc. (4DN) stock compared to peers - newser.com

Nov 21, 2025
pulisher
Nov 21, 2025

Denali Therapeutics announces board and leadership changes By Investing.com - Investing.com Nigeria

Nov 21, 2025
pulisher
Nov 21, 2025

How strong dollar benefits Denali Therapeutics Inc. (4DN) stockJuly 2025 Trends & Community Consensus Picks - newser.com

Nov 21, 2025
pulisher
Nov 20, 2025

Why Denali Therapeutics Inc. (4DN) stock benefits from AI revolution2025 Stock Rankings & Real-Time Volume Triggers - newser.com

Nov 20, 2025
pulisher
Nov 20, 2025

Is Denali Therapeutics Inc. (4DN) stock at risk of policy regulationTrade Risk Report & AI Based Buy and Sell Signals - newser.com

Nov 20, 2025
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Nov 20, 2025

Is Denali Therapeutics Inc. stock a defensive play in 2025Market Risk Summary & Risk Managed Investment Strategies - newser.com

Nov 20, 2025
pulisher
Nov 19, 2025

Will Denali Therapeutics Inc. stock gain from lower inflationSwing Trade & High Conviction Investment Ideas - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Is Denali Therapeutics Inc. stock a contrarian buy2025 Trade Ideas & Accurate Buy Signal Notifications - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Is Denali Therapeutics Inc. (4DN) stock positioned for digital growth eraQuarterly Investment Review & Capital Efficient Trade Techniques - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Published on: 2025-11-19 17:06:18 - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Can Denali Therapeutics Inc. (4DN) stock resist broad market declinesTrade Exit Summary & Weekly Stock Breakout Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Applying sector rotation models to Denali Therapeutics Inc.Quarterly Risk Review & Weekly Return Optimization Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

How Denali Therapeutics Inc. (4DN) stock performs in easing cyclesJuly 2025 Institutional & Momentum Based Trading Ideas - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Denali Therapeutics Inc. (4DN.MU) Stock Price, News, Quote & History - Yahoo! Finance Canada

Nov 19, 2025
pulisher
Nov 19, 2025

Is Denali Therapeutics Inc. stock supported by strong cash flowsEarnings Miss & Daily Volume Surge Trade Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Will Denali Therapeutics Inc. (4DN) stock outperform small cap peers2025 Price Momentum & Reliable Trade Execution Plans - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Why Denali Therapeutics Inc. stock remains on watchlists2025 Top Decliners & Technical Buy Zone Confirmations - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Will Denali Therapeutics Inc. (4DN) stock beat international competitionJuly 2025 Macro Moves & Reliable Volume Spike Trade Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Why Denali Therapeutics Inc. stock is favored by pension fundsTrade Analysis Report & Verified Swing Trading Watchlist - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Will Denali Therapeutics Inc. stock outperform Nasdaq indexIndex Update & Weekly High Return Stock Forecasts - newser.com

Nov 19, 2025

Denali Therapeutics Inc Stock (DNLI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$38.92
price up icon 1.38%
$30.45
price up icon 1.36%
$102.06
price up icon 0.29%
$95.59
price down icon 1.42%
biotechnology ONC
$347.72
price down icon 0.45%
$198.76
price down icon 0.44%
Cap:     |  Volume (24h):