16.28
price down icon0.61%   -0.10
after-market After Hours: 16.50 0.22 +1.35%
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Denali Therapeutics Inc stock is traded at $16.28, with a volume of 1.23M. It is down -0.61% in the last 24 hours and up +12.12% over the past month. Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegeneration disease. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, DNL747, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others.
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Previous Close:
$16.38
Open:
$16.25
24h Volume:
1.23M
Relative Volume:
0.64
Market Cap:
$2.38B
Revenue:
$340.81M
Net Income/Loss:
$-419.65M
P/E Ratio:
-5.7123
EPS:
-2.85
Net Cash Flow:
$-402.10M
1W Performance:
+2.01%
1M Performance:
+12.12%
6M Performance:
-2.22%
1Y Performance:
-37.29%
1-Day Range:
Value
$15.90
$16.45
1-Week Range:
Value
$15.90
$17.02
52-Week Range:
Value
$10.57
$33.33

Denali Therapeutics Inc Stock (DNLI) Company Profile

Name
Name
Denali Therapeutics Inc
Name
Phone
(650) 866-8547
Name
Address
161 OYSTER POINT BLVD., SOUTH SAN FRANCISCO
Name
Employee
486
Name
Twitter
Name
Next Earnings Date
2025-08-08
Name
Latest SEC Filings
Name
DNLI's Discussions on Twitter

Compare DNLI with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
DNLI
Denali Therapeutics Inc
16.28 2.39B 340.81M -419.65M -402.10M -2.85
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
425.57 107.66B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
651.80 68.74B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
456.04 58.93B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
818.50 50.51B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
189.60 41.29B 447.02M -1.18B -868.57M -6.1812

Denali Therapeutics Inc Stock (DNLI) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-10-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Mar-07-25 Resumed Morgan Stanley Overweight
Feb-11-25 Initiated Deutsche Bank Buy
Jan-07-25 Initiated Robert W. Baird Outperform
Jan-03-25 Initiated William Blair Outperform
Dec-16-24 Upgrade Stifel Hold → Buy
Oct-10-24 Resumed Raymond James Mkt Perform
Oct-07-24 Downgrade Cantor Fitzgerald Overweight → Neutral
Dec-13-23 Initiated Citigroup Buy
Nov-20-23 Resumed JP Morgan Overweight
Oct-24-23 Resumed Cantor Fitzgerald Overweight
Sep-06-23 Initiated B. Riley Securities Buy
Jan-30-23 Initiated SVB Securities Outperform
Dec-05-22 Initiated Cowen Outperform
Nov-02-22 Upgrade BTIG Research Neutral → Buy
Nov-02-22 Initiated BofA Securities Buy
Jun-23-22 Initiated Berenberg Buy
Dec-10-21 Resumed Raymond James Mkt Perform
Sep-21-21 Initiated Oppenheimer Outperform
Sep-01-21 Initiated SMBC Nikko Outperform
May-18-21 Initiated UBS Buy
Feb-26-21 Reiterated H.C. Wainwright Buy
Feb-10-21 Upgrade Cantor Fitzgerald Neutral → Overweight
Nov-11-20 Reiterated H.C. Wainwright Buy
Oct-16-20 Downgrade BTIG Research Buy → Neutral
Sep-14-20 Resumed JP Morgan Overweight
Aug-20-20 Reiterated H.C. Wainwright Buy
Mar-13-20 Upgrade Evercore ISI In-line → Outperform
Feb-28-20 Upgrade Wedbush Neutral → Outperform
Feb-24-20 Initiated Jefferies Buy
Feb-19-20 Initiated Stifel Hold
Jan-27-20 Upgrade Goldman Neutral → Buy
Sep-26-19 Initiated Wedbush Neutral
Sep-13-19 Initiated Nomura Buy
Aug-09-19 Initiated BTIG Research Buy
Jun-26-19 Initiated H.C. Wainwright Buy
Nov-15-18 Initiated Cantor Fitzgerald Overweight
Nov-12-18 Initiated Janney Buy
Mar-12-18 Downgrade Evercore ISI Outperform → In-line
Jan-02-18 Initiated Evercore ISI Outperform
Jan-02-18 Initiated Goldman Neutral
Jan-02-18 Initiated JP Morgan Overweight
Jan-02-18 Initiated Morgan Stanley Overweight
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Denali Therapeutics Inc Stock (DNLI) Latest News

pulisher
Nov 02, 2025

Why analysts remain bullish on Denali Therapeutics Inc. stockPrice Action & Growth Focused Investment Plans - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Comparing Denali Therapeutics Inc. in custom built stock radarsPrice Action & Daily Oversold Stock Bounce Ideas - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Can Denali Therapeutics Inc. (4DN) stock test all time highsJuly 2025 Final Week & Expert Approved Trade Ideas - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Is Denali Therapeutics Inc. stock a contrarian buyStop Loss & Growth Focused Investment Plans - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Pier Capital LLC Sells 20,708 Shares of Denali Therapeutics Inc. $DNLI - MarketBeat

Nov 02, 2025
pulisher
Nov 02, 2025

Denali Therapeutics Inc. $DNLI Shares Purchased by State of New Jersey Common Pension Fund D - MarketBeat

Nov 02, 2025
pulisher
Nov 02, 2025

Published on: 2025-11-02 03:18:16 - newser.com

Nov 02, 2025
pulisher
Nov 02, 2025

Will Denali Therapeutics Inc. (4DN) stock enhance shareholder valueStock Surge & Free Safe Entry Trade Signal Reports - newser.com

Nov 02, 2025
pulisher
Nov 01, 2025

Detecting price anomalies in Denali Therapeutics Inc. with AIPortfolio Risk Report & Free Fast Gain Swing Trade Alerts - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Is Denali Therapeutics Inc. stock ready for a breakoutGDP Growth & Consistent Profit Trade Alerts - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Is Denali Therapeutics Inc. stock a top momentum play2025 Market Overview & AI Forecast for Swing Trade Picks - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Will Denali Therapeutics Inc. (4DN) stock outperform small cap peers2025 Dividend Review & Stepwise Trade Execution Plans - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Is Denali Therapeutics Inc. stock a dividend growth opportunityQuarterly Portfolio Review & Risk Controlled Daily Plans - newser.com

Nov 01, 2025
pulisher
Nov 01, 2025

Savvy Advisors Inc. Invests $1.37 Million in Denali Therapeutics Inc. $DNLI - MarketBeat

Nov 01, 2025
pulisher
Oct 31, 2025

Denali Therapeutics Inc expected to post a loss of 75 cents a shareEarnings Preview - TradingView

Oct 31, 2025
pulisher
Oct 31, 2025

Applying sector rotation models to Denali Therapeutics Inc.Fed Meeting & Safe Capital Growth Stock Tips - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Does Denali Therapeutics Inc. qualify in momentum factor screeningJuly 2025 Price Swings & Expert Curated Trade Setups - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Can Denali Therapeutics Inc. (4DN) stock resist broad market declinesShort Setup & Verified Swing Trading Watchlists - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Will Denali Therapeutics Inc. stock rally after Fed decisionsJuly 2025 Pullbacks & Low Volatility Stock Suggestions - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

How Denali Therapeutics Inc. (4DN) stock gains from tech spendingEarnings Risk Report & Low Risk Profit Maximizing Plans - newser.com

Oct 31, 2025
pulisher
Oct 31, 2025

Published on: 2025-10-30 23:48:28 - newser.com

Oct 31, 2025
pulisher
Oct 29, 2025

Denali Therapeutics (DNLI) to Release Quarterly Earnings on Wednesday - MarketBeat

Oct 29, 2025
pulisher
Oct 29, 2025

Published on: 2025-10-29 04:42:36 - newser.com

Oct 29, 2025

Denali Therapeutics Inc Stock (DNLI) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$37.54
price up icon 1.62%
$93.48
price up icon 0.96%
$28.61
price down icon 0.21%
$103.91
price down icon 0.73%
biotechnology ONC
$310.48
price up icon 0.73%
$189.60
price down icon 2.38%
Cap:     |  Volume (24h):