Sarepta Therapeutics Inc (SRPT)

SRPT's stock fell 7.93% as some analysts voiced concerns that upcoming confirmatory trial data for its gene therapy to treat Duchenne muscular dystrophy (DMD) may not be enough to secure approval for expanded use.

https://www.reuters.com/business/healthcare-pharmaceuticals/sarepta-slumps-concerns-emerge-around-upcoming-gene-therapy-data-2023-06-23/

Before the market opened on Thursday, shares of Sarepta Therapeutics (NASDAQ: SRPT) experienced a decline of roughly 10% in pre-market trading. This drop occurred following a report stating that the U.S. Food and Drug Administration (FDA) staff had a leaning towards rejecting the company's Duchenne muscular dystrophy gene therapy, but a senior official intervened.

https://www.investing.com/news/stock-market-news/sarepta-tumbles-10-on-report-fda-leaned-toward-rejecting-duchenne-therapy-432SI-3054655

Sarepta Therapeutics's stock is going down today after the announcement of an advisory meeting for the SRP-9001's development (the first gene therapy) with the FDA, since their gene therapy isn't believed to be beneficial. The meeting comes as the company was preparing for the SRP-9001 regulatory action date on May 29, 2023.