4.325
price up icon3.05%   0.145
 
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Prime Medicine Inc stock is traded at $4.325, with a volume of 1.45M. It is up +3.05% in the last 24 hours and up +23.07% over the past month. Prime Medicine Inc is a biotechnology company committed to delivering genetic therapies to address diseases by deploying gene editing technology, Prime Editing. The Prime Editing technology is a next-generation technology that can search and replace to restore normal genetic function in the genome and can treat a wide spectrum of diseases with high unmet medical needs and efficient and broad gene editing technology.
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Previous Close:
$4.18
Open:
$4.31
24h Volume:
1.45M
Relative Volume:
0.39
Market Cap:
$780.71M
Revenue:
-
Net Income/Loss:
$-217.44M
P/E Ratio:
-1.9931
EPS:
-2.17
Net Cash Flow:
$-205.20M
1W Performance:
+10.74%
1M Performance:
+23.07%
6M Performance:
+2.32%
1Y Performance:
+42.17%
1-Day Range:
Value
$4.25
$4.56
1-Week Range:
Value
$3.8225
$4.70
52-Week Range:
Value
$1.11
$6.94

Prime Medicine Inc Stock (PRME) Company Profile

Name
Name
Prime Medicine Inc
Name
Phone
617-465-0013
Name
Address
60 FIRST ST., CAMBRIDGE
Name
Employee
214
Name
Twitter
Name
Next Earnings Date
2025-10-31
Name
Latest SEC Filings
Name
PRME's Discussions on Twitter

Compare PRME with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
PRME
Prime Medicine Inc
4.325 754.53M 0 -217.44M -205.20M -2.17
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
471.94 120.98B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
768.19 80.15B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
865.84 51.56B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
359.23 47.74B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ONC
Beone Medicines Ltd Adr
335.08 37.38B 4.98B 69.59M 525.67M 0.5197

Prime Medicine Inc Stock (PRME) Upgrades & Downgrades

Date Action Analyst Rating Change
May-27-25 Downgrade Citigroup Buy → Neutral
May-20-25 Downgrade H.C. Wainwright Buy → Neutral
May-20-25 Downgrade JP Morgan Overweight → Neutral
Dec-10-24 Initiated JMP Securities Mkt Outperform
May-20-24 Initiated H.C. Wainwright Buy
May-16-24 Upgrade Citigroup Neutral → Buy
Apr-22-24 Initiated Chardan Capital Markets Buy
Apr-08-24 Initiated TD Cowen Buy
Apr-03-24 Initiated Wedbush Outperform
Jan-16-24 Downgrade Stifel Buy → Hold
Dec-08-23 Initiated Citigroup Neutral
Oct-09-23 Initiated BMO Capital Markets Outperform
Jul-31-23 Initiated Guggenheim Buy
Apr-18-23 Initiated Stifel Buy
Nov-14-22 Initiated Goldman Neutral
Nov-14-22 Initiated JP Morgan Overweight
Nov-14-22 Initiated Jefferies Buy
Nov-14-22 Initiated Morgan Stanley Equal-Weight
View All

Prime Medicine Inc Stock (PRME) Latest News

pulisher
Jan 26, 2026

Prime Medicine (NASDAQ:PRME) Shares Down 5.6%What's Next? - MarketBeat

Jan 26, 2026
pulisher
Jan 26, 2026

Prime Medicine (NYSE:PRME) Trading Down 5.5%What's Next? - MarketBeat

Jan 26, 2026
pulisher
Jan 23, 2026

JonesTrading Maintains Prime Medicine(PRME.US) With Buy Rating, Maintains Target Price $5 - 富途牛牛

Jan 23, 2026
pulisher
Jan 22, 2026

Prime Medicine (NASDAQ:PRME) Shares Up 10.5%Here's Why - MarketBeat

Jan 22, 2026
pulisher
Jan 22, 2026

Prime Medicine (NYSE:PRME) Shares Up 12.4%Time to Buy? - MarketBeat

Jan 22, 2026
pulisher
Jan 20, 2026

Should I trade or invest in Prime Medicine IncJuly 2025 Highlights & Accurate Entry and Exit Point Alerts - baoquankhu1.vn

Jan 20, 2026
pulisher
Jan 20, 2026

Targets Report: Is NEOV in accumulation or distribution phaseGap Down & Weekly Breakout Stock Alerts - baoquankhu1.vn

Jan 20, 2026
pulisher
Jan 19, 2026

How Prime Medicine Inc. stock reacts to bond yieldsEarnings Trend Report & Long-Term Safe Return Strategies - bollywoodhelpline.com

Jan 19, 2026
pulisher
Jan 18, 2026

Sumitomo Mitsui Trust Group Inc. Boosts Stake in Prime Medicine, Inc. $PRME - MarketBeat

Jan 18, 2026
pulisher
Jan 15, 2026

Prime Medicine (NASDAQ:PRME) Trading Down 7.9%Should You Sell? - MarketBeat

Jan 15, 2026
pulisher
Jan 15, 2026

Prime Medicine (NYSE:PRME) Trading Down 5.7%What's Next? - MarketBeat

Jan 15, 2026
pulisher
Jan 15, 2026

Prime Medicine, Inc. (NYSE:PRME) Receives Consensus Recommendation of "Moderate Buy" from Analysts - MarketBeat

Jan 15, 2026
pulisher
Jan 14, 2026

Prime Medicine (NASDAQ:PRME) Shares Up 8.4%Should You Buy? - MarketBeat

Jan 14, 2026
pulisher
Jan 12, 2026

Prime Medicine updates corporate strategy for Prime Editing platform - TipRanks

Jan 12, 2026
pulisher
Jan 12, 2026

Prime Medicine, Inc. Updates on Prime Editing Developments - TradingView

Jan 12, 2026
pulisher
Jan 10, 2026

What technical charts say about Prime Medicine Inc. stock2025 Market Overview & Verified Chart Pattern Signals - Улправда

Jan 10, 2026
pulisher
Jan 09, 2026

Is Prime Medicine Inc. stock a safe buy before earningsJuly 2025 Outlook & Technical Entry and Exit Tips - Улправда

Jan 09, 2026
pulisher
Jan 08, 2026

How Prime Medicine Inc. stock benefits from tech adoptionWeekly Market Summary & Weekly Return Optimization Alerts - ulpravda.ru

Jan 08, 2026
pulisher
Jan 08, 2026

What hedge fund activity signals for Prime Medicine Inc. stockIndex Update & AI Based Buy/Sell Signal Reports - ulpravda.ru

Jan 08, 2026
pulisher
Jan 08, 2026

Prime Medicine initiated with an outperform at LifeSci Capital - MSN

Jan 08, 2026
pulisher
Jan 08, 2026

Los Angeles Daily NewsPrime Medicine, Inc.Common Stock (Nasdaq:PRME) Stock Quote - FinancialContent

Jan 08, 2026
pulisher
Jan 07, 2026

Prime Medicine (NYSE:PRME) Trading 7.5% HigherWhat's Next? - MarketBeat

Jan 07, 2026
pulisher
Jan 07, 2026

How Prime Medicine Inc. stock reacts to oil pricesBullish Engulfing Patterns & High Profit Trading Alerts - Улправда

Jan 07, 2026
pulisher
Jan 07, 2026

Prime Medicine to Present at 44th Annual J.P. Morgan Healthcare Conference - The Manila Times

Jan 07, 2026
pulisher
Jan 07, 2026

WaterWorldPrime Medicine to Present at 44th Annual J.P. Morgan Healthcare Conference - FinancialContent

Jan 07, 2026
pulisher
Jan 03, 2026

Prime Medicine, Inc. (PRME) announces NEJM publication of PM359 data - MSN

Jan 03, 2026
pulisher
Jan 02, 2026

Gene Therapy: 5 Biotech Stocks Chasing the $36B Prize - Benzinga

Jan 02, 2026
pulisher
Dec 31, 2025

Prime: Maintaining "Buy" On Solidified Catalysts For Wilson's Disease And Beyond - Seeking Alpha

Dec 31, 2025
pulisher
Dec 31, 2025

Prime Medicine (NYSE:PRME) Trading Down 3.3%Here's What Happened - MarketBeat

Dec 31, 2025
pulisher
Dec 31, 2025

LifeSci Capital Initiates Prime Medicine (PRME), Highlights One-and-Done Potential in Liver and Lung Diseases - Insider Monkey

Dec 31, 2025
pulisher
Dec 30, 2025

Prime Medicine, Inc. (PRME) Announces NEJM Publication Of PM359 Data - Insider Monkey

Dec 30, 2025
pulisher
Dec 29, 2025

10 Best Biotech Penny Stocks to Buy According to Analysts - Insider Monkey

Dec 29, 2025
pulisher
Dec 25, 2025

Lifesci Capital Predicts Prime Medicine FY2025 Earnings - MarketBeat

Dec 25, 2025
pulisher
Dec 24, 2025

Prime Medicine (NASDAQ:PRME) Trading Down 3.8%Here's What Happened - MarketBeat

Dec 24, 2025
pulisher
Dec 24, 2025

Prime Medicine (NYSE:PRME) Stock Price Down 4.2%Should You Sell? - MarketBeat

Dec 24, 2025
pulisher
Dec 24, 2025

Prime Medicine (NASDAQ:PRME) Upgraded at Lifesci Capital - MarketBeat

Dec 24, 2025
pulisher
Dec 23, 2025

LifeSci Capital Initiates Coverage of Prime Medicine (PRME) with Outperform Recommendation - Nasdaq

Dec 23, 2025
pulisher
Dec 23, 2025

Lifesci Capital Begins Coverage on Prime Medicine (NYSE:PRME) - MarketBeat

Dec 23, 2025
pulisher
Dec 23, 2025

LifeSci Capital Initiates Prime Medicine(PRME.US) With Buy Rating, Announces Target Price $6 - 富途牛牛

Dec 23, 2025
pulisher
Dec 23, 2025

Prime Medicine: Buy Rating on Prime Editing Platform Targeting High-Value Liver and Lung Genetic Diseases, Led by PM577 in Wilson’s Disease - TipRanks

Dec 23, 2025
pulisher
Dec 23, 2025

Prime Medicine initiated with an Outperform at LifeSci Capital - TipRanks

Dec 23, 2025
pulisher
Dec 23, 2025

LifeSci Initiates Prime Medicine at Outperform With $6 Price Target - marketscreener.com

Dec 23, 2025
pulisher
Dec 22, 2025

Prime Medicine Earnings Notes - Trefis

Dec 22, 2025
pulisher
Dec 21, 2025

Prime Medicine, Inc.(NasdaqGM: PRME) added to S&P Biotechnology Select Industry Index - marketscreener.com

Dec 21, 2025
pulisher
Dec 21, 2025

Prime Medicine announces NEJM publication of PM359 data - MSN

Dec 21, 2025
pulisher
Dec 21, 2025

Prime Medicine, Inc. (NYSE:PRME) Given Consensus Rating of "Moderate Buy" by Brokerages - MarketBeat

Dec 21, 2025
pulisher
Dec 20, 2025

Quarterly Recap: How Prime Medicine Inc. stock reacts to oil pricesWatch List & Safe Entry Trade Reports - Улправда

Dec 20, 2025
pulisher
Dec 20, 2025

Risks Report: Why Prime Medicine Inc. stock remains resilient2025 Market Trends & Real-Time Buy Signal Notifications - Улправда

Dec 20, 2025
pulisher
Dec 19, 2025

Why Prime Medicine Inc. stock remains resilientTrade Exit Summary & Weekly High Return Stock Forecasts - Улправда

Dec 19, 2025
pulisher
Dec 19, 2025

Can Prime Medicine Inc. stock hit record highs againJuly 2025 News Drivers & Weekly High Conviction Ideas - Улправда

Dec 19, 2025
pulisher
Dec 19, 2025

Can Prime Medicine Inc. stock withstand economic slowdownTrade Signal Summary & Weekly Top Gainers Alerts - Улправда

Dec 19, 2025

Prime Medicine Inc Stock (PRME) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prime Medicine Inc Stock (PRME) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
NELSEN ROBERT
Director
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners XII, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners X, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
Liu David R.
10% Owner
Jun 30 '25
Buy
2.52
21,000
52,830
20,240,945
Liu David R.
10% Owner
Jun 23 '25
Buy
2.16
21,000
45,402
20,219,945
Liu David R.
10% Owner
Jun 16 '25
Buy
1.49
21,000
31,196
20,198,945
Liu David R.
10% Owner
Jun 11 '25
Buy
1.60
21,000
33,590
20,177,945
Brudnick Richard
Chief Business Officer
May 20 '25
Buy
1.19
20,000
23,790
20,000
LEE ANN L.
Chief Technical Officer
May 21 '25
Buy
1.13
100,000
113,000
100,000
Reine Allan
Chief Executive Officer
May 21 '25
Buy
1.18
125,000
147,150
125,000
$99.78
price up icon 2.05%
$104.18
price up icon 1.63%
$34.39
price up icon 2.75%
$119.16
price up icon 1.01%
$163.94
price up icon 2.61%
biotechnology ONC
$335.02
price down icon 0.71%
Cap:     |  Volume (24h):