3.61
price down icon9.52%   -0.38
pre-market  Pre-market:  3.66   0.05   +1.39%
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Prime Medicine Inc stock is traded at $3.61, with a volume of 3.14M. It is down -9.52% in the last 24 hours and up +15.34% over the past month. Prime Medicine Inc is a biotechnology company focused on developing a new class of genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its program, PM577 for Wilson Disease, is designed to initially correct the H1069Q mutation in the ATP7B gene and is supported by preclinical data showing targeted correction and restoration of copper homeostasis in animal models. In addition, PM647 is being developed for alpha-1 antitrypsin deficiency, or AATD, another liver targeted disease with substantial unmet need.
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Previous Close:
$3.99
Open:
$3.95
24h Volume:
3.14M
Relative Volume:
0.54
Market Cap:
$654.77M
Revenue:
$4.03M
Net Income/Loss:
$-198.37M
P/E Ratio:
-2.8765
EPS:
-1.255
Net Cash Flow:
$-158.74M
1W Performance:
+3.14%
1M Performance:
+15.34%
6M Performance:
-1.37%
1Y Performance:
-36.11%
1-Day Range:
Value
$0.00
$0.00
1-Week Range:
Value
$3.3001
$4.14
52-Week Range:
Value
$2.67
$6.65

Prime Medicine Inc Stock (PRME) Company Profile

Name
Name
Prime Medicine Inc
Name
Phone
617-465-0013
Name
Address
60 FIRST ST., CAMBRIDGE
Name
Employee
146
Name
Twitter
Name
Next Earnings Date
2026-11-06
Name
Latest SEC Filings
Name
PRME's Discussions on Twitter

Compare PRME vs VRTX, MRNA, REGN, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRME icon
PRME
Prime Medicine Inc
3.61 654.77M 4.03M -198.37M -158.74M -1.255
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
507.00 128.50B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
213.74 85.33B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
762.81 78.54B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
812.30 51.08B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
193.95 41.57B 742.00K -1.37B -1.07B -7.0731

Prime Medicine Inc Stock (PRME) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-25-26 Resumed Chardan Capital Markets Buy
Aug-19-26 Initiated BMO Capital Markets Outperform
Jun-29-26 Upgrade H.C. Wainwright Neutral → Buy
Mar-12-26 Initiated Oppenheimer Outperform
May-27-25 Downgrade Citigroup Buy → Neutral
May-20-25 Downgrade H.C. Wainwright Buy → Neutral
May-20-25 Downgrade JP Morgan Overweight → Neutral
Dec-10-24 Initiated JMP Securities Mkt Outperform
May-20-24 Initiated H.C. Wainwright Buy
May-16-24 Upgrade Citigroup Neutral → Buy
Apr-22-24 Initiated Chardan Capital Markets Buy
Apr-08-24 Initiated TD Cowen Buy
Apr-03-24 Initiated Wedbush Outperform
Jan-16-24 Downgrade Stifel Buy → Hold
Dec-08-23 Initiated Citigroup Neutral
Oct-09-23 Initiated BMO Capital Markets Outperform
Jul-31-23 Initiated Guggenheim Buy
Apr-18-23 Initiated Stifel Buy
Nov-14-22 Initiated Goldman Neutral
Nov-14-22 Initiated JP Morgan Overweight
Nov-14-22 Initiated Jefferies Buy
Nov-14-22 Initiated Morgan Stanley Equal-Weight
View All

Prime Medicine Inc Stock (PRME) Latest News

pulisher
Oct 12, 2026

Prime Medicine Stock Rallies Nearly 26% in a Month: Here's Why - Zacks Investment Research

Oct 12, 2026
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Oct 06, 2026

Prime Medicine (PRME) Stock Draws Traders On FDA Trial Wins - Timothy Sykes

Oct 06, 2026
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Oct 06, 2026

PRME Stock Climbs As FDA Greenlights Gene-Editing Trials - StocksToTrade

Oct 06, 2026
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Oct 05, 2026

Prime Medicine, Inc. (PRME) stock price, news, quote and history - Yahoo Finance Australia

Oct 05, 2026
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Oct 05, 2026

Prime Medicine Announces First Patient Dosed in Global Phase 1/2 Clinical Trial of PM577a for H1069Q-Mutated Wilson Disease - GlobeNewswire Inc.

Oct 05, 2026
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Sep 29, 2026

Prime Medicine (NASDAQ:PRME) Stock Price Up 6.1%Still a Buy? - MarketBeat

Sep 29, 2026
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Sep 25, 2026

PRME Stock Dips As Prime Medicine Faces Steep Losses - StocksToTrade

Sep 25, 2026
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Sep 25, 2026

Prime Medicine Stock Slips As Traders Digest Weak Margins - StocksToTrade

Sep 25, 2026
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Sep 25, 2026

Prime Medicine: A Buy Due To BLA Filing H1 '27 And In Vivo Therapy Development (PRME) - Seeking Alpha

Sep 25, 2026
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Sep 24, 2026

Prime Medicine stock surges on FDA IND clearance - Yahoo Finance

Sep 24, 2026
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Sep 24, 2026

FDA clears testing of a genetic treatment aimed at a variant carried by about 100,000 people in the U.S. - Stock Titan

Sep 24, 2026
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Sep 24, 2026

Prime Medicine (NasdaqGM:PRME) Stock Forecast & Analyst Predictions - Simply Wall Street

Sep 24, 2026
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Sep 22, 2026

Prime Medicine, Inc. (NASDAQ:PRME) Receives Average Recommendation of "Moderate Buy" from Analysts - MarketBeat

Sep 22, 2026
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Sep 21, 2026

Prime Medicine (Nasdaq:PRME)Stock Analysis - Simply Wall Street

Sep 21, 2026
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Sep 17, 2026

Prime Medicine (NASDAQ:PRME): What's Behind Its Sudden Share Price Jump? - kalkinemedia.com

Sep 17, 2026
pulisher
Sep 17, 2026

Prime Medicine (NASDAQ:PRME) Shares Up 11.8%Should You Buy? - MarketBeat

Sep 17, 2026
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Sep 12, 2026

Prime Medicine (NASDAQ:PRME) Rating Increased to Hold at Wall Street Zen - MarketBeat

Sep 12, 2026
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Sep 11, 2026

Prime Medicine (NASDAQ:PRME) Stock Price Down 4.3%Here's What Happened - MarketBeat

Sep 11, 2026
pulisher
Sep 03, 2026

A gene-editing company sets three September conference appearances - Stock Titan

Sep 03, 2026
pulisher
Sep 03, 2026

Prime Medicine to Participate in Upcoming Investor Conferences - Yahoo Finance

Sep 03, 2026
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Sep 02, 2026

BlackRock Inc. Acquires Shares of 9,602,041 Prime Medicine, Inc. $PRME - MarketBeat

Sep 02, 2026
pulisher
Aug 28, 2026

Prime Medicine, Inc. (NASDAQ:PRME) Given Average Recommendation of "Moderate Buy" by Brokerages - MarketBeat

Aug 28, 2026
pulisher
Aug 27, 2026

Prime Medicine (NASDAQ:PRME) Upgraded to Strong-Buy at Chardan Capital - marketbeat.com

Aug 27, 2026
pulisher
Aug 26, 2026

ADAR1 Capital Management LLC Makes New Investment in Prime Medicine, Inc. $PRME - MarketBeat

Aug 26, 2026
pulisher
Aug 26, 2026

Prime Medicine (NASDAQ:PRME) Stock Price Down 4.7%What's Next? - MarketBeat

Aug 26, 2026
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Aug 25, 2026

Prime Medicine (NASDAQ:PRME) Shares Up 6.3%Here's What Happened - MarketBeat

Aug 25, 2026
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Aug 20, 2026

Prime Medicine (NASDAQ:PRME) Trading Down 6.9%Should You Sell? - MarketBeat

Aug 20, 2026
pulisher
Aug 20, 2026

Prime Medicine (NASDAQ:PRME) Rating Increased to Strong-Buy at BMO Capital Markets - MarketBeat

Aug 20, 2026
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Aug 19, 2026

Prime Medicine Company Profile & Introduction - Moomoo

Aug 19, 2026
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Aug 19, 2026

Prime Medicine (NASDAQ:PRME) Shares Gap UpStill a Buy? - MarketBeat

Aug 19, 2026
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Aug 19, 2026

PRIME MEDICINE, INC. : BMO INITIATES COVERAGE WITH OUTPERFORM RATING; PRICE TARGET $9 - Bitget

Aug 19, 2026
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Aug 19, 2026

PRME Initiated Coverage by BMO Capital -- Rating Set to Outperfo - GuruFocus

Aug 19, 2026
pulisher
Aug 19, 2026

Prime (PRME) Results Breakdown: The Available Earnings Metric Delivers a Beat for the Current Session; Investor Response: Shares Fall 3.79% on the DayConsensus Beat Rate - vinanet.vn

Aug 19, 2026
pulisher
Aug 19, 2026

BMO initiates Prime Medicine stock with outperform rating By Investing.com - Investing.com Canada

Aug 19, 2026
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Aug 18, 2026

Alphabet Inc. Takes Position in Prime Medicine, Inc. $PRME - MarketBeat

Aug 18, 2026
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Aug 17, 2026

Prime Medicine Number of Employees 2026 | Employee Count & Headcount Data - Revelio Labs

Aug 17, 2026
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Aug 17, 2026

LifeSci Capital Maintains Prime Medicine(PRME.US) With Buy Rating, Maintains Target Price $6 - Moomoo

Aug 17, 2026
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Aug 15, 2026

Prime Medicine: Soon In The Clinic (NASDAQ:PRME) - Seeking Alpha

Aug 15, 2026
pulisher
Aug 15, 2026

Prime Medicine, Inc. Stock 12‑Month Price Target Cut to $6.92, Implies 124% Upside - TradingView

Aug 15, 2026
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Aug 14, 2026

PRME Q2 2026 Earnings: Narrower-than-Expected Loss Marks Progress as Stock SlipsProfit Announcement - vinanet.vn

Aug 14, 2026
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Aug 12, 2026

Q3 EPS Estimates for Prime Medicine Boosted by HC Wainwright - MarketBeat

Aug 12, 2026
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Aug 11, 2026

Prime Medicine: An Initial Prognosis (NASDAQ:PRME) - Seeking Alpha

Aug 11, 2026
pulisher
Aug 11, 2026

Analysts Have Conflicting Sentiments on These Healthcare Companies: Lakefront Biotherapeutics (LKFT), Prime Medicine, Inc. (PRME) and Electrocore (ECOR) - The Globe and Mail

Aug 11, 2026
pulisher
Aug 10, 2026

Prime Medicine (NASDAQ:PRME) Trading Up 7.3%Still a Buy? - MarketBeat

Aug 10, 2026
pulisher
Aug 10, 2026

Prime Medicine's (PRME) "Buy" Rating Reaffirmed at HC Wainwright - MarketBeat

Aug 10, 2026
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Aug 10, 2026

Weekly Recap: Q2 loss/runway into 2027 and PM647 arbitration win, IND Q3 - TradingView

Aug 10, 2026
pulisher
Aug 10, 2026

H.C. Wainwright Maintains Prime Medicine(PRME.US) With Buy Rating, Maintains Target Price $8 - Moomoo

Aug 10, 2026
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Aug 10, 2026

Renaissance Technologies LLC Sells 408,120 Shares of Prime Medicine, Inc. $PRME - MarketBeat

Aug 10, 2026
pulisher
Aug 10, 2026

PRME Q2 2026 Earnings: Narrower-Than-Expected Loss Drives 3.57% Stock AdvanceGuidance Downgrade Alert - vinanet.vn

Aug 10, 2026
pulisher
Aug 08, 2026

Prime Medicine (NASDAQ:PRME) Stock Rating Upgraded by Wall Street Zen - MarketBeat

Aug 08, 2026

Prime Medicine Inc Stock (PRME) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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WVE WVE
$3.28
price down icon 5.20%
$7.36
price down icon 5.88%
$14.59
price down icon 9.99%
$19.69
price down icon 6.77%
$11.32
price down icon 0.61%
$6.54
price up icon 0.00%
Cap:     |  Volume (24h):