2.97
price up icon0.00%   0.00
after-market After Hours: 2.99 0.02 +0.67%
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Prime Medicine Inc stock is traded at $2.97, with a volume of 2.33M. It is up +0.00% in the last 24 hours and down -19.73% over the past month. Prime Medicine Inc is a biotechnology company focused on developing a new class of genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its program, PM577 for Wilson Disease, is designed to initially correct the H1069Q mutation in the ATP7B gene and is supported by preclinical data showing targeted correction and restoration of copper homeostasis in animal models. In addition, PM647 is being developed for alpha-1 antitrypsin deficiency, or AATD, another liver targeted disease with substantial unmet need.
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Previous Close:
$2.97
Open:
$3.01
24h Volume:
2.33M
Relative Volume:
0.93
Market Cap:
$536.43M
Revenue:
$4.63M
Net Income/Loss:
$-201.14M
P/E Ratio:
-2.1614
EPS:
-1.3741
Net Cash Flow:
$-167.10M
1W Performance:
+10.00%
1M Performance:
-19.73%
6M Performance:
-19.95%
1Y Performance:
+130.23%
1-Day Range:
Value
$2.89
$3.05
1-Week Range:
Value
$2.70
$3.0999
52-Week Range:
Value
$1.18
$6.94

Prime Medicine Inc Stock (PRME) Company Profile

Name
Name
Prime Medicine Inc
Name
Phone
617-465-0013
Name
Address
60 FIRST ST., CAMBRIDGE
Name
Employee
146
Name
Twitter
Name
Next Earnings Date
2026-05-14
Name
Latest SEC Filings
Name
PRME's Discussions on Twitter

Compare PRME vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRME icon
PRME
Prime Medicine Inc
2.97 536.43M 4.63M -201.14M -167.10M -1.3741
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
435.93 110.28B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
634.62 66.98B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
808.43 50.15B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
295.50 39.71B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
154.89 32.22B 742.00K -1.37B -1.07B -7.0731

Prime Medicine Inc Stock (PRME) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-12-26 Initiated Oppenheimer Outperform
May-27-25 Downgrade Citigroup Buy → Neutral
May-20-25 Downgrade H.C. Wainwright Buy → Neutral
May-20-25 Downgrade JP Morgan Overweight → Neutral
Dec-10-24 Initiated JMP Securities Mkt Outperform
May-20-24 Initiated H.C. Wainwright Buy
May-16-24 Upgrade Citigroup Neutral → Buy
Apr-22-24 Initiated Chardan Capital Markets Buy
Apr-08-24 Initiated TD Cowen Buy
Apr-03-24 Initiated Wedbush Outperform
Jan-16-24 Downgrade Stifel Buy → Hold
Dec-08-23 Initiated Citigroup Neutral
Oct-09-23 Initiated BMO Capital Markets Outperform
Jul-31-23 Initiated Guggenheim Buy
Apr-18-23 Initiated Stifel Buy
Nov-14-22 Initiated Goldman Neutral
Nov-14-22 Initiated JP Morgan Overweight
Nov-14-22 Initiated Jefferies Buy
Nov-14-22 Initiated Morgan Stanley Equal-Weight
View All

Prime Medicine Inc Stock (PRME) Latest News

pulisher
May 23, 2026

PRME Q1 2026 Earnings: EPS Worse Than Expected as Pre-Revenue Biotech Advances PipelinePro Level Trade Signals - Newser

May 23, 2026
pulisher
May 22, 2026

PRME Q1 2026 Earnings: EPS Misses Estimates as Pre-Revenue Biotech Focuses on Pipeline ProgressEPS Consistency Score - Newser

May 22, 2026
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May 19, 2026

Prime Medicine (PRME) Q1 2026 Disappoints — EPS $-0.28 Below $-0.26 ViewsEarnings Turnaround - Newser

May 19, 2026
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May 19, 2026

Prime Medicine slips after Q4 updates - MSN

May 19, 2026
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May 13, 2026

Prime Medicine (PRME) Reports Q1 EPS - Yahoo Finance

May 13, 2026
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May 12, 2026

10 Best Penny Stocks to Buy Before They Explode - Insider Monkey

May 12, 2026
pulisher
May 12, 2026

Oppenheimer Maintains Prime Medicine(PRME.US) With Buy Rating, Announces Target Price $11 - Moomoo

May 12, 2026
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May 11, 2026

TradingKey - TradingKey

May 11, 2026
pulisher
May 11, 2026

Prime Medicine, Inc. (PRME) reports Q1 loss, misses revenue estimates - MSN

May 11, 2026
pulisher
May 11, 2026

Number of shareholders of Prime Medicine, Inc. – NASDAQ:PRME - TradingView

May 11, 2026
pulisher
May 08, 2026

PRME Prime Medicine revenue jumps 55% YoY in Q1; shares rally 3% on growth momentum.Management Guidance - newser.com

May 08, 2026
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May 08, 2026

JonesTrading Initiates Prime Medicine(PRME.US) With Buy Rating, Announces Target Price $5 - Moomoo

May 08, 2026
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May 08, 2026

H.C. Wainwright Maintains Prime Medicine(PRME.US) With Hold Rating - Moomoo

May 08, 2026
pulisher
May 08, 2026

The opportunity most miss about Prime Medicine (PRME) (-8.65%) 2026-05-08Analyst Recommended Stocks - Newser

May 08, 2026
pulisher
May 07, 2026

Prime Medicine Inc reports results for the quarter ended March 31Earnings Summary - TradingView

May 07, 2026
pulisher
May 07, 2026

Prime Medicine (NASDAQ:PRME) Q1 Results Show Revenue Miss and Narrower Loss as Key Pipeline Milestones Loom - ChartMill

May 07, 2026
pulisher
May 07, 2026

PRIME MEDICINE ($PRME) Releases Q1 2026 Earnings - Quiver Quantitative

May 07, 2026
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May 07, 2026

[10-Q] Prime Medicine, Inc. Quarterly Earnings Report - Stock Titan

May 07, 2026
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May 07, 2026

Prime Medicine Q1 net loss narrows as R&D expenses fall - TradingView

May 07, 2026
pulisher
May 07, 2026

Prime Medicine (Nasdaq: PRME) Q1 2026 results, cash runway into 2027 and pipeline update - Stock Titan

May 07, 2026
pulisher
May 07, 2026

Prime Medicine Reports First Quarter 2026 Financial Results and Provides Business Updates - The Manila Times

May 07, 2026
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May 07, 2026

Prime Medicine targets 2 liver disease filings in 2026, data due 2027 - Stock Titan

May 07, 2026
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May 07, 2026

Top Prime Medicine (PRME) Competitors 2026 - MarketBeat

May 07, 2026
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May 05, 2026

Prime Medicine (NASDAQ:PRME) Upgraded to Sell at Wall Street Zen - MarketBeat

May 05, 2026
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May 05, 2026

PRME SEC FilingsPrime Medicine 10-K, 10-Q, 8-K Forms - Stock Titan

May 05, 2026
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Apr 28, 2026

PRME - Finviz

Apr 28, 2026
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Apr 28, 2026

PRME Stock Price, Quote & Chart | PRIME MEDICINE INC (NASDAQ:PRME) - ChartMill

Apr 28, 2026
pulisher
Apr 27, 2026

Prime Medicine, Inc. (PRME) Reports Q2 Loss, Lags Revenue Estimates - MSN

Apr 27, 2026
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Apr 27, 2026

Prime Medicine (NASDAQ:PRME) Stock Rating Lowered by Wall Street Zen - MarketBeat

Apr 27, 2026
pulisher
Apr 27, 2026

Prime Medicine, Inc. (PRME) Reports Q3 Loss, Lags Revenue Estimates - MSN

Apr 27, 2026
pulisher
Apr 25, 2026

Prime Medicine, Inc. (NASDAQ:PRME) Given Average Rating of "Moderate Buy" by Brokerages - MarketBeat

Apr 25, 2026
pulisher
Apr 24, 2026

PRME Price Today: Prime Medicine, Inc. Stock Price, Quote & Chart | MEXC - MEXC Exchange

Apr 24, 2026
pulisher
Apr 23, 2026

Prime Medicine, Inc. ($PRME) CEO 2025 Pay Revealed - Quiver Quantitative

Apr 23, 2026
pulisher
Apr 23, 2026

[ARS] Prime Medicine, Inc. SEC Filing - Stock Titan

Apr 23, 2026
pulisher
Apr 23, 2026

Prime Medicine (NASDAQ: PRME) details 2026 meeting, board elections and pay - Stock Titan

Apr 23, 2026
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Apr 23, 2026

PRME (Prime Medicine Inc.) posts 55 percent year over year Q4 2025 revenue growth, shares rise modestly. - Xã Thanh Hà

Apr 23, 2026
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Apr 23, 2026

Prime Medicine slides after pricing $125.4M stock offering - MSN

Apr 23, 2026
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Apr 23, 2026

HC Wainwright & Co. Downgrades Prime Medicine (PRME) - MSN

Apr 23, 2026
pulisher
Apr 23, 2026

Prime Medicine (PRME) Appoints Svetlana Makhni as Chief Financial Officer - Yahoo Finance

Apr 23, 2026
pulisher
Apr 22, 2026

Bristol Myers Squibb (BMY) – Gene Editing Partner Prime Medicine (PRME) Announces Strategic CFO Hire, Bullish Analyst InitiationRisk Report - Cổng thông tin điện tử tỉnh Lào Cai

Apr 22, 2026
pulisher
Apr 22, 2026

Prime Medicine (PRME) Financials 2026Income Statement and Balance Sheet - MarketBeat

Apr 22, 2026
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Apr 19, 2026

Wall Street Zen Upgrades Prime Medicine (NASDAQ:PRME) to Sell - MarketBeat

Apr 19, 2026
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Apr 18, 2026

Sumitomo Mitsui Trust Group Inc. Sells 384,418 Shares of Prime Medicine, Inc. $PRME - MarketBeat

Apr 18, 2026
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Apr 17, 2026

Prime Medicine (PRME) awards CFO 800,000 stock options at $3.67 - Stock Titan

Apr 17, 2026
pulisher
Apr 17, 2026

Prime Medicine (PRME) CFO Makhni Svetlana Ni submits initial Form 3 - Stock Titan

Apr 17, 2026

Prime Medicine Inc Stock (PRME) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prime Medicine Inc Stock (PRME) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
NELSEN ROBERT
Director
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners XII, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
ARCH Venture Partners X, LLC
10% Owner
Aug 01 '25
Buy
3.30
3,030,300
9,999,990
6,230,300
Liu David R.
10% Owner
Jun 30 '25
Buy
2.52
21,000
52,830
20,240,945
Liu David R.
10% Owner
Jun 23 '25
Buy
2.16
21,000
45,402
20,219,945
Liu David R.
10% Owner
Jun 16 '25
Buy
1.49
21,000
31,196
20,198,945
Liu David R.
10% Owner
Jun 11 '25
Buy
1.60
21,000
33,590
20,177,945
$29.66
price down icon 0.98%
$92.25
price up icon 0.12%
$108.87
price up icon 2.48%
$53.86
price down icon 1.17%
ONC ONC
$302.44
price down icon 2.52%
$154.89
price up icon 2.20%
Cap:     |  Volume (24h):