4.23
price down icon9.23%   -0.43
after-market After Hours: 4.30 0.07 +1.65%
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Prime Medicine Inc stock is traded at $4.23, with a volume of 3.81M. It is down -9.23% in the last 24 hours and up +11.02% over the past month. Prime Medicine Inc is a biotechnology company committed to delivering genetic therapies to address diseases by deploying gene editing technology, Prime Editing. The Prime Editing technology is a next-generation technology that can search and replace to restore normal genetic function in the genome and can treat a wide spectrum of diseases with high unmet medical needs and efficient and broad gene editing technology.
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Previous Close:
$4.66
Open:
$4.46
24h Volume:
3.81M
Relative Volume:
1.16
Market Cap:
$763.56M
Revenue:
-
Net Income/Loss:
$-217.44M
P/E Ratio:
-1.9493
EPS:
-2.17
Net Cash Flow:
$-205.20M
1W Performance:
+10.44%
1M Performance:
+11.02%
6M Performance:
+26.65%
1Y Performance:
+89.26%
1-Day Range:
Value
$4.20
$4.51
1-Week Range:
Value
$3.85
$4.7652
52-Week Range:
Value
$1.11
$6.94

Prime Medicine Inc Stock (PRME) Company Profile

Name
Name
Prime Medicine Inc
Name
Phone
617-465-0013
Name
Address
60 FIRST ST., CAMBRIDGE
Name
Employee
214
Name
Twitter
Name
Next Earnings Date
2026-02-27
Name
Latest SEC Filings
Name
PRME's Discussions on Twitter

Compare PRME vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
PRME
Prime Medicine Inc
4.23 841.18M 0 -217.44M -205.20M -2.17
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
474.27 123.47B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
766.66 83.60B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
748.72 46.83B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
318.65 43.11B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
297.04 34.79B 4.98B 69.60M 525.67M 0.5198

Prime Medicine Inc Stock (PRME) Upgrades & Downgrades

Date Action Analyst Rating Change
May-27-25 Downgrade Citigroup Buy → Neutral
May-20-25 Downgrade H.C. Wainwright Buy → Neutral
May-20-25 Downgrade JP Morgan Overweight → Neutral
Dec-10-24 Initiated JMP Securities Mkt Outperform
May-20-24 Initiated H.C. Wainwright Buy
May-16-24 Upgrade Citigroup Neutral → Buy
Apr-22-24 Initiated Chardan Capital Markets Buy
Apr-08-24 Initiated TD Cowen Buy
Apr-03-24 Initiated Wedbush Outperform
Jan-16-24 Downgrade Stifel Buy → Hold
Dec-08-23 Initiated Citigroup Neutral
Oct-09-23 Initiated BMO Capital Markets Outperform
Jul-31-23 Initiated Guggenheim Buy
Apr-18-23 Initiated Stifel Buy
Nov-14-22 Initiated Goldman Neutral
Nov-14-22 Initiated JP Morgan Overweight
Nov-14-22 Initiated Jefferies Buy
Nov-14-22 Initiated Morgan Stanley Equal-Weight
View All

Prime Medicine Inc Stock (PRME) Latest News

pulisher
09:15 AM

Prime Medicine, Inc. (PRME) Reports Q4 Loss, Misses Revenue Estimates - Nasdaq

09:15 AM
pulisher
08:41 AM

Prime Medicine Reports 2025 Results, Advances Gene Editing Pipeline - TipRanks

08:41 AM
pulisher
08:26 AM

Prime Medicine 2025 Net Loss Narrows as Revenue Rises -- Shares Fall Pre-Bell - marketscreener.com

08:26 AM
pulisher
08:20 AM

Earnings Flash (PRME) Prime Medicine Posts 2025 Total Revenue $4.6M, vs. FactSet Est of $5.7M - marketscreener.com

08:20 AM
pulisher
08:13 AM

Prime Medicine : March 2026 Corporate Presentation - marketscreener.com

08:13 AM
pulisher
08:12 AM

Prime Medicine 2025 net loss widens, hurt by higher R&D expenses - TradingView

08:12 AM
pulisher
08:10 AM

Prime Medicine Reports Full Year 2025 Financial Results and Provides Business Updates - The Manila Times

08:10 AM
pulisher
08:02 AM

Prime Medicine (Nasdaq: PRME) details 2025 results, cash runway and gene-editing milestones - Stock Titan

08:02 AM
pulisher
08:00 AM

Prime Medicine posts $201M loss advancing gene-editing therapies - Stock Titan

08:00 AM
pulisher
Mar 02, 2026

PRME Financials: Income Statement, Balance Sheet & Cash Flow - Stock Titan

Mar 02, 2026
pulisher
Mar 01, 2026

Investment Report: What is the target price for Prime Medicine Inc stockJuly 2025 Fed Impact & Low Risk High Reward Trade Ideas - baoquankhu1.vn

Mar 01, 2026
pulisher
Feb 25, 2026

Stock Traders Buy Large Volume of Call Options on Prime Medicine (NYSE:PRME) - MarketBeat

Feb 25, 2026
pulisher
Feb 25, 2026

Prime Medicine to Participate in Upcoming Investor Conferences - Bitget

Feb 25, 2026
pulisher
Feb 25, 2026

Prime Medicine lines up three March investor talks in Boston and Miami Beach - Stock Titan

Feb 25, 2026
pulisher
Feb 24, 2026

Prime Medicine (NYSE:PRME) Trading 10.3% HigherStill a Buy? - MarketBeat

Feb 24, 2026
pulisher
Feb 23, 2026

PRME (Prime Medicine) PB Ratio : 3.72 (As of Feb. 23, 2026) - GuruFocus

Feb 23, 2026
pulisher
Feb 20, 2026

Prime Medicine (NASDAQ:PRME) Trading Up 1.2%Here's What Happened - MarketBeat

Feb 20, 2026
pulisher
Feb 18, 2026

Jacob Funds Bets on Prime Medicine (PRME), a Next-Generation Gene Therapy Company - Insider Monkey

Feb 18, 2026
pulisher
Feb 14, 2026

Prime Medicine, Inc. $PRME Shares Acquired by Alphabet Inc. - MarketBeat

Feb 14, 2026
pulisher
Feb 13, 2026

Aug Catalysts: Is Seacoast Banking Corporation of Florida impacted by rising rates2025 Market Outlook & Weekly Watchlist of Top Performers - baoquankhu1.vn

Feb 13, 2026
pulisher
Feb 12, 2026

Should I average down on Prime Medicine Inc. stockWeekly Investment Recap & Reliable Price Breakout Alerts - mfd.ru

Feb 12, 2026
pulisher
Feb 10, 2026

Aug Analyst Calls: Is Prime Medicine Inc stock a smart retirement pick2025 Biggest Moves & Scalable Portfolio Growth Ideas - baoquankhu1.vn

Feb 10, 2026
pulisher
Feb 09, 2026

Prime Medicine, Inc. (NYSE:PRME) Receives Average Recommendation of "Moderate Buy" from Brokerages - MarketBeat

Feb 09, 2026
pulisher
Feb 05, 2026

Earnings Miss: Will Prime Medicine Inc stock hit new highs in YEARJuly 2025 Spike Watch & AI Driven Price Forecasts - baoquankhu1.vn

Feb 05, 2026
pulisher
Feb 04, 2026

Prime Medicine Advances Wilson Disease Pipeline With New Prescreening Study - TipRanks

Feb 04, 2026
pulisher
Feb 02, 2026

Institutional Owners May Ignore Prime Medicine, Inc.'s (NASDAQ:PRME) Recent US$66m Market Cap Decline as Longer-term Profits Stay in the Green - 富途牛牛

Feb 02, 2026
pulisher
Jan 31, 2026

Institutional investors in Prime Medicine, Inc. (NASDAQ:PRME) see US$110m decrease in market cap last week, although long-term gains have benefitted them. - simplywall.st

Jan 31, 2026
pulisher
Jan 29, 2026

What is the target price for Prime Medicine Inc. stockJuly 2025 Weekly Recap & Verified Trade Idea Suggestions - mfd.ru

Jan 29, 2026
pulisher
Jan 27, 2026

Aug Selloffs: Should I average down on Prime Medicine Inc stockJuly 2025 Drop Watch & Intraday High Probability Setup Alerts - baoquankhu1.vn

Jan 27, 2026
pulisher
Jan 27, 2026

Favourable Signals For Prime Medicine: Numerous Insiders Acquired Stock - Yahoo Finance

Jan 27, 2026
pulisher
Jan 26, 2026

Prime Medicine (NASDAQ:PRME) Shares Down 5.6%What's Next? - MarketBeat

Jan 26, 2026
pulisher
Jan 26, 2026

Prime Medicine (NYSE:PRME) Trading Down 5.5%What's Next? - MarketBeat

Jan 26, 2026
pulisher
Jan 23, 2026

JonesTrading Maintains Prime Medicine(PRME.US) With Buy Rating, Maintains Target Price $5 - 富途牛牛

Jan 23, 2026
pulisher
Jan 22, 2026

Prime Medicine (NASDAQ:PRME) Shares Up 10.5%Here's Why - MarketBeat

Jan 22, 2026
pulisher
Jan 22, 2026

Prime Medicine (NYSE:PRME) Shares Up 12.4%Time to Buy? - MarketBeat

Jan 22, 2026
pulisher
Jan 20, 2026

Should I trade or invest in Prime Medicine IncJuly 2025 Highlights & Accurate Entry and Exit Point Alerts - baoquankhu1.vn

Jan 20, 2026
pulisher
Jan 20, 2026

Targets Report: Is NEOV in accumulation or distribution phaseGap Down & Weekly Breakout Stock Alerts - baoquankhu1.vn

Jan 20, 2026
pulisher
Jan 19, 2026

How Prime Medicine Inc. stock reacts to bond yieldsEarnings Trend Report & Long-Term Safe Return Strategies - bollywoodhelpline.com

Jan 19, 2026
pulisher
Jan 18, 2026

Sumitomo Mitsui Trust Group Inc. Boosts Stake in Prime Medicine, Inc. $PRME - MarketBeat

Jan 18, 2026
pulisher
Jan 15, 2026

Prime Medicine (NASDAQ:PRME) Trading Down 7.9%Should You Sell? - MarketBeat

Jan 15, 2026
pulisher
Jan 15, 2026

Prime Medicine (NYSE:PRME) Trading Down 5.7%What's Next? - MarketBeat

Jan 15, 2026
pulisher
Jan 15, 2026

Prime Medicine, Inc. (NYSE:PRME) Receives Consensus Recommendation of "Moderate Buy" from Analysts - MarketBeat

Jan 15, 2026
pulisher
Jan 14, 2026

Prime Medicine (NASDAQ:PRME) Shares Up 8.4%Should You Buy? - MarketBeat

Jan 14, 2026
pulisher
Jan 14, 2026

PRME: Prime Editing's modular platform drives rapid clinical progress and strategic partnerships for broad disease impact - TradingView

Jan 14, 2026
pulisher
Jan 12, 2026

Prime Medicine updates corporate strategy for Prime Editing platform - TipRanks

Jan 12, 2026
pulisher
Jan 12, 2026

Prime Medicine, Inc. Updates on Prime Editing Developments - TradingView

Jan 12, 2026
pulisher
Jan 10, 2026

What technical charts say about Prime Medicine Inc. stock2025 Market Overview & Verified Chart Pattern Signals - Улправда

Jan 10, 2026
pulisher
Jan 09, 2026

Is Prime Medicine Inc. stock a safe buy before earningsJuly 2025 Outlook & Technical Entry and Exit Tips - Улправда

Jan 09, 2026
pulisher
Jan 08, 2026

How Prime Medicine Inc. stock benefits from tech adoptionWeekly Market Summary & Weekly Return Optimization Alerts - ulpravda.ru

Jan 08, 2026
pulisher
Jan 08, 2026

What hedge fund activity signals for Prime Medicine Inc. stockIndex Update & AI Based Buy/Sell Signal Reports - ulpravda.ru

Jan 08, 2026
pulisher
Jan 08, 2026

Prime Medicine initiated with an outperform at LifeSci Capital - MSN

Jan 08, 2026

Prime Medicine Inc Stock (PRME) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$49.83
price down icon 5.71%
$27.85
price down icon 0.89%
$47.48
price up icon 0.02%
$100.76
price down icon 6.25%
$147.00
price up icon 0.46%
biotechnology ONC
$297.04
price down icon 5.51%
Cap:     |  Volume (24h):