25.02
price down icon3.21%   -0.83
after-market After Hours: 24.95 -0.07 -0.28%
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Upstream Bio Inc Stock (UPB) Price History

The historical daily chart and data for Upstream Bio Inc stock (UPB), show that the latest closing stock price as of November 03, 2025, is $25.02.
  • Upstream Bio Inc all-time high stock price is $29.46, occurred on November 06, 2024.
  • The lowest Upstream Bio Inc stock price recorded was $5.14 on April 09, 2025. Since then, Upstream Bio Inc's stock price has risen over 386.77% to $25.02 now.
  • The 52-week high stock price for UPB is $29.46, representing a 17.75% increase from the current share price, occurred on November 06, 2024.
  • The 52-week low stock price for UPB is $5.14, indicating a -79.46% decrease from the current share price, occurred on April 09, 2025.
The table below shows more information about UPB historical price data:
Date High Low High - Low Volume % Change
Nov 03, 2025 $26.22 $24.76 $1.46 316,704.0 -3.21%
Oct 31, 2025 $26.25 $25.48 $0.77 215,051.0 +0.31%
Oct 30, 2025 $26.90 $23.93 $2.97 352,907.0 +6.53%
Oct 29, 2025 $25.33 $23.95 $1.38 197,799.0 -2.62%
Oct 28, 2025 $25.09 $23.50 $1.59 417,580.0 +5.34%
Oct 27, 2025 $24.00 $21.89 $2.11 412,638.0 +7.87%
Oct 24, 2025 $22.14 $21.44 $0.70 185,990.0 +3.45%
Oct 23, 2025 $22.42 $21.02 $1.40 241,381.0 -4.60%
Oct 22, 2025 $22.62 $21.90 $0.72 450,360.0 -0.81%
Oct 21, 2025 $23.03 $22.14 $0.89 475,311.0 -3.12%
Oct 20, 2025 $23.34 $21.17 $2.17 786,405.0 +9.92%
Oct 17, 2025 $22.15 $20.65 $1.50 370,797.0 -5.88%
Oct 16, 2025 $22.39 $21.39 $1.00 396,512.0 +2.72%
Oct 15, 2025 $21.87 $20.12 $1.75 477,856.0 +8.56%
Oct 14, 2025 $20.65 $19.63 $1.02 261,587.0 -0.50%
Oct 13, 2025 $20.31 $19.56 $0.75 218,214.0 +2.34%
Oct 10, 2025 $20.68 $19.46 $1.22 271,771.0 -0.86%
Oct 09, 2025 $20.09 $18.61 $1.48 636,358.0 +4.60%
Oct 08, 2025 $19.30 $18.72 $0.58 328,406.0 +1.34%
Oct 07, 2025 $18.96 $18.18 $0.785 190,145.0 -1.58%

Upstream Bio Inc Stock (UPB) Year by Year Price History

In this detailed analysis, we present a comprehensive overview of the price movements of Upstream Bio Inc stock over the years. By exploring the year-by-year data, investors can gain valuable insights into the historical performance and volatility of UPB shares. From significant milestones and fluctuations to notable trends, this in-depth examination of Upstream Bio Inc stock price history provides a foundation for understanding how the company's stock has evolved over time.

Upstream Bio Inc Stock (UPB) Price History 2025

Month High Low High - Low Volume % Change
Nov, 2025 $26.22 $24.76 $1.46 633,408.0 -3.21%
Oct, 2025 $26.90 $18.05 $8.85 8,125,871.0 +37.43%
Sep, 2025 $21.03 $15.55 $5.48 12,893,529.0 +9.81%
Aug, 2025 $19.37 $14.21 $5.16 9,057,642.0 +11.89%
Jul, 2025 $16.15 $10.54 $5.61 8,863,349.0 +39.44%
Jun, 2025 $12.10 $9.25 $2.85 10,827,671.0 +18.96%
May, 2025 $9.90 $7.79 $2.11 8,016,902.0 -0.32%
Apr, 2025 $10.50 $5.14 $5.36 6,329,494.0 +51.31%
Mar, 2025 $10.08 $6.12 $3.96 5,002,930.0 -22.82%
Feb, 2025 $10.65 $6.65 $4.00 4,866,797.0 -26.37%
Jan, 2025 $18.95 $9.29 $9.66 4,964,040.0 -34.49%

Upstream Bio Inc Stock (UPB) Price History 2024

Month High Low High - Low Volume % Change
Dec, 2024 $24.98 $14.97 $10.01 8,803,116.0 -21.72%
Nov, 2024 $29.46 $17.09 $12.37 4,900,376.0 -11.81%
Oct, 2024 $27.68 $20.74 $6.94 4,827,709.0 +0.00%
$37.30
price down icon 0.64%
$28.71
price up icon 0.35%
$101.57
price up icon 8.65%
$103.95
price up icon 0.04%
biotechnology ONC
$311.86
price up icon 0.44%
$186.23
price down icon 1.78%
Cap:     |  Volume (24h):