19.97
price up icon1.47%   0.29
 
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Upstream Bio Inc stock is traded at $19.97, with a volume of 556.12K. It is up +1.47% in the last 24 hours and up +28.84% over the past month. Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases.
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Previous Close:
$19.68
Open:
$19.81
24h Volume:
556.12K
Relative Volume:
1.14
Market Cap:
$1.08B
Revenue:
$2.22M
Net Income/Loss:
$-40.51M
P/E Ratio:
-15.54
EPS:
-1.2847
Net Cash Flow:
$-46.53M
1W Performance:
+16.58%
1M Performance:
+28.84%
6M Performance:
+135.77%
1Y Performance:
+0.00%
1-Day Range:
Value
$19.09
$20.42
1-Week Range:
Value
$16.66
$21.03
52-Week Range:
Value
$5.14
$29.46

Upstream Bio Inc Stock (UPB) Company Profile

Name
Name
Upstream Bio Inc
Name
Phone
781-208-2466
Name
Address
890 WINTER STREET, SUITE 200, WALTHAM
Name
Employee
0
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
UPB's Discussions on Twitter

Compare UPB with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
UPB
Upstream Bio Inc
19.97 1.06B 2.22M -40.51M -46.53M -1.2847
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
396.12 101.77B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
573.38 60.12B 14.21B 4.46B 3.56B 39.68
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
452.00 59.45B 2.46B -319.09M -52.09M -2.47
Biotechnology icon
ARGX
Argen X Se Adr
750.78 44.90B 3.06B 1.28B 447.35M 21.30
Biotechnology icon
ONC
Beone Medicines Ltd Adr
341.80 35.07B 3.81B -644.79M -669.77M -6.24

Upstream Bio Inc Stock (UPB) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-05-24 Initiated JP Morgan Overweight
Nov-05-24 Initiated Piper Sandler Overweight
Nov-05-24 Initiated TD Cowen Buy
Nov-05-24 Initiated William Blair Outperform

Upstream Bio Inc Stock (UPB) Latest News

pulisher
07:25 AM

Upstream Bio Inc. stock momentum explained2025 Price Momentum & Expert Approved Trade Ideas - Newser

07:25 AM
pulisher
05:36 AM

Is Upstream Bio Inc. meeting your algorithmic filter criteriaWeekly Trade Report & Safe Capital Growth Trade Ideas - Newser

05:36 AM
pulisher
Sep 06, 2025

Visual trend scoring systems applied to Upstream Bio Inc.M&A Rumor & Daily Stock Trend Reports - Newser

Sep 06, 2025
pulisher
Sep 06, 2025

Historical volatility pattern of Upstream Bio Inc. visualizedEarnings Miss & Community Supported Trade Ideas - Newser

Sep 06, 2025
pulisher
Sep 06, 2025

Using fundamentals and technicals on Upstream Bio Inc.Trade Analysis Summary & Weekly Stock Breakout Alerts - Newser

Sep 06, 2025
pulisher
Sep 06, 2025

Statistical indicators supporting Upstream Bio Inc.’s strength2025 Analyst Calls & Technical Confirmation Trade Alerts - Newser

Sep 06, 2025
pulisher
Sep 06, 2025

Using portfolio simulators with Upstream Bio Inc. included2025 Buyback Activity & Expert Verified Stock Movement Alerts - Newser

Sep 06, 2025
pulisher
Sep 06, 2025

How to interpret RSI for Upstream Bio Inc. stock2025 Market Sentiment & Safe Entry Trade Reports - Newser

Sep 06, 2025
pulisher
Sep 05, 2025

Upstream Bio’s Phase 2 VIBRANT Trial Results and Strategic Implications for Long-Term Growth - AInvest

Sep 05, 2025
pulisher
Sep 05, 2025

Is Upstream Bio Inc. stock poised for growthMarket Performance Summary & Consistent Profit Focused Trading Strategies - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

Is now a turning point for Upstream Bio Inc.Portfolio Gains Report & Accurate Buy Signal Notifications - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

Will Upstream Bio Inc. benefit from geopolitical trendsJuly 2025 Catalysts & Short-Term Swing Trade Alerts - خودرو بانک

Sep 05, 2025
pulisher
Sep 05, 2025

Can Upstream Bio Inc. outperform in the next rally2025 Trading Volume Trends & AI Powered Buy and Sell Recommendations - خودرو بانک

Sep 05, 2025
pulisher
Sep 05, 2025

Long term hold vs stop loss in Upstream Bio Inc.Price Action & Free Technical Confirmation Trade Alerts - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

Is Upstream Bio Inc. stock a top performer YTDWeekly Trend Report & Free Safe Capital Growth Stock Tips - خودرو بانک

Sep 05, 2025
pulisher
Sep 05, 2025

Transcript : Upstream Bio, Inc.Special Call - MarketScreener

Sep 05, 2025
pulisher
Sep 05, 2025

Is Upstream Bio Inc. forming a bottoming baseJuly 2025 Market Mood & Real-Time Stock Movement Alerts - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

Trend analysis for Upstream Bio Inc. this weekPortfolio Growth Summary & Real-Time Chart Pattern Alerts - Newser

Sep 05, 2025
pulisher
Sep 05, 2025

Using economic indicators to assess Upstream Bio Inc. potentialJuly 2025 Retail & AI Enhanced Trade Execution Alerts - Newser

Sep 05, 2025
pulisher
Sep 04, 2025

Technical signs of recovery in Upstream Bio Inc.2025 Breakouts & Breakdowns & AI Powered Market Entry Strategies - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

Exit strategy if you’re trapped in Upstream Bio Inc.Trade Entry Summary & Verified Short-Term Plans - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

Upstream Bio Initiates Phase 2 Clinical Trial for COPD Drug, Verekitug - MSN

Sep 04, 2025
pulisher
Sep 04, 2025

What MACD and RSI say about Upstream Bio Inc.2025 Major Catalysts & AI Powered Buy/Sell Recommendations - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

How to build a dashboard for Upstream Bio Inc. stock2025 Top Gainers & Fast Gain Stock Tips - Newser

Sep 04, 2025
pulisher
Sep 04, 2025

Real time breakdown of Upstream Bio Inc. stock performanceMarket Performance Recap & High Accuracy Swing Entry Alerts - Newser

Sep 04, 2025
pulisher
Sep 03, 2025

Analyzing Upstream Bio Inc. with risk reward ratio chartsWeekly Profit Analysis & High Conviction Buy Zone Alerts - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Does Upstream Bio Inc. offer margin of safetyMarket Risk Report & Capital Efficiency Focused Strategies - خودرو بانک

Sep 03, 2025
pulisher
Sep 03, 2025

Will Upstream Bio Inc. outperform during market ralliesMarket Sentiment Report & Daily Entry Point Trade Alerts - خودرو بانک

Sep 03, 2025
pulisher
Sep 03, 2025

Upstream Bio Inc. stock outlook for YEAR2025 Momentum Check & High Win Rate Trade Alerts - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Is Upstream Bio Inc. a strong candidate for buy and holdQuarterly Trade Review & Reliable Breakout Stock Forecasts - خودرو بانک

Sep 03, 2025
pulisher
Sep 03, 2025

Upstream Bio Announces Positive Phase 2 Trial Results - The Globe and Mail

Sep 03, 2025
pulisher
Sep 03, 2025

Developing predictive dashboards with Upstream Bio Inc. dataRate Cut & Technical Pattern Recognition Alerts - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Upstream Bio shares rise 1.18% premarket after reporting positive top-line results from the Phase 2 VIBrant trial of Verekitug for the treatment of chronic rhinosinusitis with nasal polyps. - AInvest

Sep 03, 2025
pulisher
Sep 03, 2025

Upstream Bio, Inc. $UPB Shares Sold by Charles Schwab Investment Management Inc. - Defense World

Sep 03, 2025
pulisher
Sep 03, 2025

Signal strength of Upstream Bio Inc. stock in tech scannersRecession Risk & Low Drawdown Investment Ideas - Newser

Sep 03, 2025
pulisher
Sep 03, 2025

Upstream Bio Reports Positive Top-Line Results from the - GlobeNewswire

Sep 03, 2025
pulisher
Sep 03, 2025

Upstream Bio Shares Surge 18.27% on Strong Phase 2 Trial Data for Verekitug - AInvest

Sep 03, 2025
pulisher
Sep 02, 2025

Technical Heatmap Flags Upstream Bio Inc. for WatchCPI Data & Safe Entry Zone Tips - beatles.ru

Sep 02, 2025
pulisher
Sep 02, 2025

Verekitug heads to late-stage trials after Phase II success - Yahoo Finance

Sep 02, 2025
pulisher
Sep 02, 2025

Upstream's New Sinus Treatment Cuts Need For Surgery, Early Trial FindsUpstream Bio (NASDAQ:UPB) - Benzinga

Sep 02, 2025
pulisher
Sep 02, 2025

Upstream Bio’s Phase 2 win could set it up as a potential Dupixent, Tezspire competitor - Endpoints News

Sep 02, 2025

Upstream Bio Inc Stock (UPB) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Upstream Bio Inc Stock (UPB) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
ORBIMED ADVISORS LLC
Director
Oct 15 '24
Buy
17.00
825,000
14,025,000
4,554,873
AI Upstream LLC
10% Owner
Oct 15 '24
Buy
17.00
1,175,000
19,975,000
1,175,000
$86.64
price up icon 1.40%
$27.54
price up icon 0.58%
$25.98
price up icon 9.16%
$112.46
price up icon 8.66%
$145.10
price up icon 1.80%
biotechnology ONC
$341.80
price up icon 7.24%
Cap:     |  Volume (24h):