6.20
price down icon4.47%   -0.29
after-market After Hours: 6.12 -0.08 -1.29%
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Silence Therapeutics Plc Adr stock is traded at $6.20, with a volume of 255.92K. It is down -4.47% in the last 24 hours and down -22.21% over the past month. Silence Therapeutics PLC is a biotechnology company focused on discovering and developing novel molecules incorporating short-interfering ribonucleic acid or siRNA. Using its mRNAi GOLD platform, the company has generated siRNA product candidates both for its internal development pipeline as well as for out-licensed programs with third-party collaborators. Its wholly owned pipeline is focused on three therapeutic areas: cardiovascular disease, hematology, and rare diseases. The different product candidates in its pipeline are Divesiran (SLN124), a siRNA product candidate that has the potential to treat several hematological disorders; Zerlasiran (SLN360), being developed as a potential treatment to reduce cardiovascular issues; SLN-312; SLN-548; and multiple other programs.
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Previous Close:
$6.49
Open:
$6.5
24h Volume:
255.92K
Relative Volume:
0.80
Market Cap:
$292.85M
Revenue:
$840.00K
Net Income/Loss:
$-75.20M
P/E Ratio:
-3.8942
EPS:
-1.5921
Net Cash Flow:
$-65.69M
1W Performance:
+1.64%
1M Performance:
-22.21%
6M Performance:
-1.74%
1Y Performance:
+28.10%
1-Day Range:
Value
$6.20
$6.73
1-Week Range:
Value
$5.74
$6.73
52-Week Range:
Value
$4.19
$8.40

Silence Therapeutics Plc Adr Stock (SLN) Company Profile

Name
Name
Silence Therapeutics Plc Adr
Name
Phone
44-0-20-3457 6900
Name
Address
12 HAMMERSMITH GROVE, LONDON
Name
Employee
88
Name
Twitter
Name
Next Earnings Date
2026-05-14
Name
Latest SEC Filings
Name
SLN's Discussions on Twitter

Compare SLN vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
SLN icon
SLN
Silence Therapeutics Plc Adr
6.20 306.55M 840.00K -75.20M -65.69M -1.5921
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
434.52 110.03B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
638.88 67.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
806.46 50.76B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
297.45 40.12B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
151.56 32.68B 742.00K -1.37B -1.07B -7.0731

Silence Therapeutics Plc Adr Stock (SLN) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-11-25 Initiated Goldman Sell
Dec-02-24 Reiterated BMO Capital Markets Outperform
Sep-03-24 Initiated Jefferies Buy
Jan-31-24 Initiated BMO Capital Markets Outperform

Silence Therapeutics Plc Adr Stock (SLN) Latest News

pulisher
May 18, 2026

Silence Therapeutics (NASDAQ: SLN) registers $300M shelf, $100M ADSs included - Stock Titan

May 18, 2026
pulisher
May 12, 2026

Silence Therapeutics to Participate in H.C. Wainwright BioConnect Investor Conference - ChartMill

May 12, 2026
pulisher
May 04, 2026

Revenue per share of Silence Therapeutics PLC Sponsored ADR – DUS:XRP2 - TradingView

May 04, 2026
pulisher
May 03, 2026

Book value per share of Silence Therapeutics PLC Sponsored ADR – DUS:XRP2 - TradingView

May 03, 2026
pulisher
May 02, 2026

Silence Therapeutics (SLN) soars 19.0%: Is further upside left in the stock? - MSN

May 02, 2026
pulisher
May 01, 2026

Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Short Interest Up 13.3% in April - MarketBeat

May 01, 2026
pulisher
Apr 28, 2026

Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Given Average Rating of "Moderate Buy" by Brokerages - MarketBeat

Apr 28, 2026
pulisher
Apr 25, 2026

Silence Therapeutics (NASDAQ:SLN) Shares Down 1.8%Here's What Happened - MarketBeat

Apr 25, 2026
pulisher
Apr 23, 2026

Wall Street Analysts Think Silence Therapeutics (SLN) Could Surge 556.19%: Read This Before Placing a Bet - MSN

Apr 23, 2026
pulisher
Apr 22, 2026

Polycythemia Vera Market Set for Transformation: Key 9 Companies Expected to Enter by 2036 | DelveInsight - GlobeNewswire Inc.

Apr 22, 2026
pulisher
Apr 16, 2026

Silence Therapeutics (SLN) Soars 19.0%: Is Further Upside Left in the Stock? - Yahoo Finance

Apr 16, 2026
pulisher
Apr 03, 2026

Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Given Average Recommendation of "Moderate Buy" by Brokerages - marketbeat.com

Apr 03, 2026
pulisher
Apr 03, 2026

Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Given Average Recommendation of “Moderate Buy” by Brokerages - Defense World

Apr 03, 2026
pulisher
Mar 16, 2026

Why Urgent.ly Shares Are Trading Higher By Around 159%; Here Are 20 Stocks Moving Premarket - Benzinga

Mar 16, 2026
pulisher
Mar 16, 2026

What is HC Wainwright's Estimate for SLN FY2030 Earnings? - MarketBeat

Mar 16, 2026
pulisher
Mar 16, 2026

What is HC Wainwright’s Estimate for SLN FY2030 Earnings? - Defense World

Mar 16, 2026
pulisher
Mar 09, 2026

Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Receives Consensus Recommendation of "Hold" from Analysts - MarketBeat

Mar 09, 2026
pulisher
Mar 06, 2026

Silence Therapeutics Q4 Earnings Assessment - Sahm

Mar 06, 2026
pulisher
Mar 05, 2026

Wall Street Analysts See a 467.47% Upside in Silence Therapeutics (SLN): Can the Stock Really Move This High? - Yahoo Finance

Mar 05, 2026
pulisher
Mar 04, 2026

Wall Street experts predict a potential 467.47% increase for Silence Therapeutics (SLN): Is such a surge in the stock truly possible? - Bitget

Mar 04, 2026
pulisher
Feb 15, 2026

Analysts Set Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Price Target at $32.60 - Defense World

Feb 15, 2026
pulisher
Feb 12, 2026

Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Receives Consensus Rating of "Hold" from Analysts - MarketBeat

Feb 12, 2026
pulisher
Feb 10, 2026

Silence Therapeutics (NASDAQ:SLN) Shares Down 5.1%Here's What Happened - MarketBeat

Feb 10, 2026
pulisher
Feb 05, 2026

Revenues Working Against Silence Therapeutics plc's (NASDAQ:SLN) Share Price Following 27% Dive - Sahm

Feb 05, 2026
pulisher
Jan 31, 2026

Here's Why We're Watching Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation - Sahm

Jan 31, 2026
pulisher
Jan 28, 2026

Silence Therapeutics ADR share price | SLN - Hargreaves Lansdown

Jan 28, 2026
pulisher
Jan 23, 2026

H.C. Wainwright reiterates Buy rating on Silence Therapeutics stock at $75 By Investing.com - Investing.com India

Jan 23, 2026
pulisher
Jan 23, 2026

H.C. Wainwright reiterates Buy rating on Silence Therapeutics stock at $75 - Investing.com

Jan 23, 2026
pulisher
Jan 18, 2026

Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Receives Consensus Recommendation of "Hold" from Brokerages - MarketBeat

Jan 18, 2026
pulisher
Jan 15, 2026

Silence Therapeutics (NASDAQ:SLN) Trading Down 0.7%Should You Sell? - MarketBeat

Jan 15, 2026
pulisher
Jan 15, 2026

Silence Therapeutics (NASDAQ:SLN) Trading Down 0.7% – Should You Sell? - Defense World

Jan 15, 2026
pulisher
Jan 10, 2026

Silence Therapeutics Insider Ups Holding During Year - Sahm

Jan 10, 2026
pulisher
Jan 09, 2026

Comparing PMV Pharmaceuticals (NASDAQ:PMVP) & Silence Therapeutics (NASDAQ:SLN) - Defense World

Jan 09, 2026
pulisher
Jan 02, 2026

Was Autonomix Medical Inc (AMIX)’s session last reading good? - uspostnews.com

Jan 02, 2026
pulisher
Dec 29, 2025

Wall Street Analysts Believe Silence Therapeutics (SLN) Could Rally 590.66%: Here's is How to Trade - MSN

Dec 29, 2025
pulisher
Dec 24, 2025

Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Receives Average Recommendation of “Hold” from Analysts - Defense World

Dec 24, 2025
pulisher
Dec 24, 2025

Silence Therapeutics PLC Sponsored ADR (NASDAQ:SLN) Receives Average Recommendation of "Hold" from Analysts - MarketBeat

Dec 24, 2025
pulisher
Dec 22, 2025

Silence Therapeutics appoints CFO Rhonda Hellums to board of directors By Investing.com - Investing.com South Africa

Dec 22, 2025
pulisher
Dec 22, 2025

Silence Therapeutics appoints CFO Rhonda Hellums to board of directors - Investing.com

Dec 22, 2025

Silence Therapeutics Plc Adr Stock (SLN) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$29.96
price down icon 2.98%
$106.24
price down icon 3.00%
$92.14
price up icon 1.33%
$54.50
price up icon 1.77%
ONC ONC
$310.25
price up icon 0.20%
$151.56
price down icon 1.41%
Cap:     |  Volume (24h):