34.57
price up icon1.41%   0.48
pre-market  Pre-market:  32.80   -1.77   -5.12%
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Sionna Therapeutics Inc stock is traded at $34.57, with a volume of 207.71K. It is up +1.41% in the last 24 hours and down -16.33% over the past month. Sionna Therapeutics Inc is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein to deliver clinically meaningful benefit to CF patients. CF is a progressive and life-threatening genetic disease caused by inherited mutations in the CFTR gene, which heads to insufficient CFTR function. The Company is managed as one operating segment focused on the research and development of cystic fibrosis therapies.
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Previous Close:
$34.09
Open:
$34.19
24h Volume:
207.71K
Relative Volume:
0.71
Market Cap:
$1.54B
Revenue:
-
Net Income/Loss:
-
P/E Ratio:
-
EPS:
-
Net Cash Flow:
-
1W Performance:
-9.10%
1M Performance:
-16.33%
6M Performance:
+49.91%
1Y Performance:
+133.58%
1-Day Range:
Value
$33.60
$35.93
1-Week Range:
Value
$32.56
$38.37
52-Week Range:
Value
$7.255
$45.00

Sionna Therapeutics Inc Stock (SION) Company Profile

Name
Name
Sionna Therapeutics Inc
Name
Phone
617-819-2020
Name
Address
21 HICKORY DRIVE, SUITE 500, WALTHAM
Name
Employee
48
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
SION's Discussions on Twitter

Compare SION vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SION
Sionna Therapeutics Inc
34.57 1.52B 0 0 0 0.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
477.89 120.48B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
787.50 81.05B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
749.56 46.33B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
327.30 42.26B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
299.02 32.87B 5.36B 287.73M 924.18M 2.5229

Sionna Therapeutics Inc Stock (SION) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-01-25 Downgrade RBC Capital Mkts Sector Perform → Underperform
Nov-19-25 Initiated BTIG Research Buy
Sep-03-25 Initiated RBC Capital Mkts Sector Perform
Sep-03-25 Initiated Raymond James Strong Buy
Mar-04-25 Initiated Guggenheim Buy
Mar-04-25 Initiated Stifel Buy
Mar-04-25 Initiated TD Cowen Buy
View All

Sionna Therapeutics Inc Stock (SION) Latest News

pulisher
Mar 03, 2026

Reassessing Sionna Therapeutics (SION) Valuation After Recent Share Price Pullback And CF Pipeline Progress - simplywall.st

Mar 03, 2026
pulisher
Mar 02, 2026

UBS Maintains Buy on Sionna Therapeutics, Inc. (SION) March 02, 2026 - Meyka

Mar 02, 2026
pulisher
Mar 02, 2026

SION: NBD1 stabilization could transform CF care, with dual and add-on therapies advancing in clinical trials - TradingView

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics (NASDAQ:SION) Earns Buy Rating from BTIG Research - MarketBeat

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics (NASDAQ:SION) Shares Gap DownShould You Sell? - MarketBeat

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics, Inc. Reports Earnings Results for the Full Year Ended December 31, 2025 - marketscreener.com

Mar 02, 2026
pulisher
Mar 02, 2026

Guggenheim raises Sionna Therapeutics stock price target to $50 By Investing.com - Investing.com Canada

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics Inc maintains strong cash position with about $310.3 million in cash and cash equivalents, expected to fund operations into 2028 - marketscreener.com

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics Inc Maintains Strong Cash Position With About $310.3 Million In Cash And Cash Equivalents, Expected To Fund Operations Into 2028 - TradingView

Mar 02, 2026
pulisher
Mar 02, 2026

Form S-3ASR Sionna Therapeutics, - StreetInsider

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics Q4 Net Loss Narrows - marketscreener.com

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics (SION) outlines NBD1-focused cystic fibrosis drug pipeline - Stock Titan

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results - Bitget

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics 10-K: $0 Revenue, $(1.88) EPS - TradingView

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna Therapeutics (Nasdaq: SION) posts 2025 loss, ends year with $310.3M cash - Stock Titan

Mar 02, 2026
pulisher
Mar 02, 2026

Sionna backs cystic fibrosis trials with $310M cash runway to 2028 - Stock Titan

Mar 02, 2026
pulisher
Feb 27, 2026

Assessing Sionna Therapeutics (SION) Valuation As Premium P/B Meets Cooling Share Price Momentum - Yahoo Finance

Feb 27, 2026
pulisher
Feb 27, 2026

Sionna Therapeutics, Inc. (SION) Stock Analysis: A Promising 24% Upside Potential in the Biotech Arena - DirectorsTalk Interviews

Feb 27, 2026
pulisher
Feb 26, 2026

Sionna Therapeutics (NASDAQ:SION) Rating Increased to Strong-Buy at Lifesci Capital - MarketBeat

Feb 26, 2026
pulisher
Feb 26, 2026

JPMorgan Chase & Co. Cuts Stake in Sionna Therapeutics, Inc. $SION - MarketBeat

Feb 26, 2026
pulisher
Feb 25, 2026

Sionna Therapeutics, Inc. (NASDAQ:SION) Receives Average Recommendation of "Moderate Buy" from Brokerages - MarketBeat

Feb 25, 2026
pulisher
Feb 24, 2026

Citizens Initiates Coverage of Sionna Therapeutics (SION) with Market Outperform Recommendation - Nasdaq

Feb 24, 2026
pulisher
Feb 24, 2026

Sionna Therapeutics (NASDAQ:SION) Coverage Initiated by Analysts at Citizens Jmp - MarketBeat

Feb 24, 2026
pulisher
Feb 24, 2026

Market Recap: Is FIVE in a consolidation phase2025 EndofYear Setup & Free Low Drawdown Momentum Trade Ideas - baoquankhu1.vn

Feb 24, 2026
pulisher
Feb 23, 2026

Cystic fibrosis drug developer Sionna heads to key March investor events - Stock Titan

Feb 23, 2026
pulisher
Feb 23, 2026

Sionna Therapeutics to Participate in Upcoming March 2026 Investor Conferences - The Manila Times

Feb 23, 2026
pulisher
Feb 21, 2026

Sionna Therapeutics, Inc. (SION) Stock Analysis: A High-Stakes Bet on Biotech Innovation with 20.13% Upside Potential - DirectorsTalk Interviews

Feb 21, 2026
pulisher
Feb 16, 2026

Is Sionna Therapeutics Inc. still a buy after recent gainsJuly 2025 Trade Ideas & Stepwise Trade Execution Plans - mfd.ru

Feb 16, 2026
pulisher
Feb 15, 2026

Fed Meeting: Will Sionna Therapeutics Inc outperform tech stocks2025 AllTime Highs & Community Trade Idea Sharing Platform - baoquankhu1.vn

Feb 15, 2026
pulisher
Feb 15, 2026

Sionna Therapeutics Maps Mid-2026 CF Catalysts, Highlights NBD1 Stabilizers at Guggenheim Summit - Yahoo Finance

Feb 15, 2026
pulisher
Feb 14, 2026

2026 Milestones in Focus as Sionna Therapeutics Pursues NBD1 Stabilization for CFTR - AD HOC NEWS

Feb 14, 2026
pulisher
Feb 13, 2026

Sionna Therapeutics, Inc. (SION) Investor Outlook: Analyzing a 19% Potential Upside in the Biotech Sector - DirectorsTalk Interviews

Feb 13, 2026
pulisher
Feb 11, 2026

SION: NBD1 stabilizer programs target major CF mutations, with pivotal data expected mid-2026 - TradingView

Feb 11, 2026
pulisher
Feb 11, 2026

Can Sionna Therapeutics Inc. stock outperform in 2025 bull marketJuly 2025 Breakouts & Technical Confirmation Alerts - mfd.ru

Feb 11, 2026
pulisher
Feb 09, 2026

What’s the MACD signal for Sionna Therapeutics Inc.July 2025 Outlook & Risk Adjusted Buy/Sell Alerts - mfd.ru

Feb 09, 2026
pulisher
Feb 08, 2026

Volume Recap: Should you avoid Sionna Therapeutics Inc stock right nowEarnings Miss & Growth-Oriented Investment Plans - baoquankhu1.vn

Feb 08, 2026
pulisher
Feb 06, 2026

Orbimed Advisors Llc Sells 29,063 Shares of Sionna Therapeutics (NASDAQ:SION) Stock - Defense World

Feb 06, 2026
pulisher
Feb 06, 2026

Peter Thompson Sells 29,063 Shares of Sionna Therapeutics (NASDAQ:SION) Stock - Defense World

Feb 06, 2026
pulisher
Feb 06, 2026

Sionna Therapeutics (NASDAQ:SION) Shares Down 14.6% on Insider Selling - Defense World

Feb 06, 2026
pulisher
Feb 05, 2026

Sionna Therapeutics (NASDAQ:SION) Trading Down 14.6% Following Insider Selling - MarketBeat

Feb 05, 2026
pulisher
Feb 05, 2026

OrbiMed Advisors LLC sells Sionna Therapeutics (SION) stock worth $1.37m - Investing.com Australia

Feb 05, 2026
pulisher
Feb 05, 2026

OrbiMed Advisors LLC sells Sionna Therapeutics (SION) stock worth $1.37m By Investing.com - Investing.com South Africa

Feb 05, 2026
pulisher
Feb 05, 2026

Thompson Peter a. sells Sionna Therapeutics (SION) shares for $1.37m By Investing.com - Investing.com South Africa

Feb 05, 2026
pulisher
Feb 05, 2026

Thompson Peter a. sells Sionna Therapeutics (SION) shares for $1.37m - Investing.com Canada

Feb 05, 2026
pulisher
Feb 04, 2026

Sionna Therapeutics (NASDAQ:SION) Director Orbimed Advisors Llc Sells 29,063 Shares - MarketBeat

Feb 04, 2026
pulisher
Feb 04, 2026

Sionna Therapeutics to Present at the Guggenheim Securities Emerging Outlook: Biotech Summit 2026 - markets.businessinsider.com

Feb 04, 2026
pulisher
Feb 04, 2026

Sionna Therapeutics (NASDAQ:SION) Director Sells $1,295,628.54 in Stock - MarketBeat

Feb 04, 2026
pulisher
Jan 31, 2026

Support Test: Whats the outlook for Sionna Therapeutics Incs sectorTrade Risk Summary & Smart Allocation Stock Reports - baoquankhu1.vn

Jan 31, 2026
pulisher
Jan 31, 2026

Sionna Therapeutics, Inc. (NASDAQ:SION) Receives Average Rating of "Moderate Buy" from Analysts - MarketBeat

Jan 31, 2026
pulisher
Jan 30, 2026

TPG GP A, LLC Reduces Stake in Sionna Therapeutics Inc - GuruFocus

Jan 30, 2026
pulisher
Jan 30, 2026

Sionna Therapeutics, Inc. (SION) Stock Analysis: Biotech’s Promising Prospects with 5.7% Upside Potential - DirectorsTalk Interviews

Jan 30, 2026

Sionna Therapeutics Inc Stock (SION) Financials Data

There is no financial data for Sionna Therapeutics Inc (SION). Check out other stocks for more information.

Revenue

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Net Income

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Cash Flow

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EPS

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Sionna Therapeutics Inc Stock (SION) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Thompson Peter A.
Director
Feb 02 '26
Sale
44.57
1,890
84,237
3,559,765
ORBIMED ADVISORS LLC
Director
Feb 03 '26
Sale
44.58
29,063
1,295,629
3,530,702
ORBIMED ADVISORS LLC
Director
Feb 02 '26
Sale
44.57
1,890
84,237
3,559,765
TPG GP A, LLC
10% Owner
Jan 22 '26
Sale
40.00
250,000
10,000,000
6,494,962
$47.43
price down icon 0.11%
$29.52
price up icon 6.00%
$57.80
price up icon 15.99%
$103.80
price up icon 3.02%
$149.88
price up icon 1.96%
biotechnology ONC
$299.02
price up icon 0.67%
Cap:     |  Volume (24h):