4.38
price down icon6.61%   -0.31
after-market After Hours: 4.40 0.02 +0.46%
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Sionna Therapeutics Inc stock is traded at $4.38, with a volume of 790.32K. It is down -6.61% in the last 24 hours and down -44.20% over the past month. Sionna Therapeutics Inc is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein to deliver clinically meaningful benefits to CF patients. CF is a progressive and life-threatening genetic disease caused by inherited mutations in the CFTR gene, which heads to insufficient CFTR function. The Company is managed as one operating segment focused on the research and development of cystic fibrosis therapies.
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Previous Close:
$4.69
Open:
$4.69
24h Volume:
790.32K
Relative Volume:
0.82
Market Cap:
$198.03M
Revenue:
Net Income/Loss:
$-85.57M
P/E Ratio:
-2.2853
EPS:
-1.9166
Net Cash Flow:
$-72.14M
1W Performance:
-7.79%
1M Performance:
-44.20%
6M Performance:
-89.51%
1Y Performance:
-85.06%
1-Day Range:
Value
$4.365
$4.795
1-Week Range:
Value
$4.365
$5.12
52-Week Range:
Value
$4.01
$54.97

Sionna Therapeutics Inc Stock (SION) Company Profile

Name
Name
Sionna Therapeutics Inc
Name
Phone
617-819-2020
Name
Address
21 HICKORY DRIVE, SUITE 500, WALTHAM
Name
Employee
59
Name
Twitter
Name
Next Earnings Date
2026-11-04
Name
Latest SEC Filings
Name
SION's Discussions on Twitter

Compare SION vs VRTX, MRNA, REGN, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
SION icon
SION
Sionna Therapeutics Inc
4.38 198.03M 0 -85.57M -72.14M -1.9166
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
485.22 122.98B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
216.25 86.33B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
753.12 77.54B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
802.64 50.47B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
188.44 40.39B 742.00K -1.37B -1.07B -7.0731

Sionna Therapeutics Inc Stock (SION) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-10-26 Downgrade BTIG Research Buy → Neutral
Aug-10-26 Downgrade Citizens Mkt Outperform → Mkt Perform
Aug-10-26 Downgrade Guggenheim Buy → Neutral
Aug-10-26 Upgrade RBC Capital Mkts Underperform → Sector Perform
Aug-10-26 Downgrade Raymond James Strong Buy → Mkt Perform
Aug-10-26 Downgrade Stifel Buy → Hold
Aug-10-26 Downgrade Wedbush Outperform → Neutral
May-05-26 Initiated Wedbush Outperform
Feb-24-26 Initiated Citizens Mkt Outperform
Dec-01-25 Downgrade RBC Capital Mkts Sector Perform → Underperform
Nov-19-25 Initiated BTIG Research Buy
Sep-03-25 Initiated RBC Capital Mkts Sector Perform
Sep-03-25 Initiated Raymond James Strong Buy
Mar-04-25 Initiated Guggenheim Buy
Mar-04-25 Initiated Stifel Buy
Mar-04-25 Initiated TD Cowen Buy
View All

Sionna Therapeutics Inc Stock (SION) Latest News

pulisher
Oct 06, 2026

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Sionna Therapeutics, Inc.SION - GlobeNewswire Inc.

Oct 06, 2026
pulisher
Sep 21, 2026

Ra Capital Management sells $21.8m in Sionna Therapeutics shares By Investing.com - Investing.com Nigeria

Sep 21, 2026
pulisher
Sep 21, 2026

Ra Capital Management sells $21.8m in Sionna Therapeutics shares By Investing.com - Investing.com Canada

Sep 21, 2026
pulisher
Sep 21, 2026

RA Capital’s Sionna (NASDAQ: SION) stock sale wasn’t under a preset trading plan - Stock Titan

Sep 21, 2026
pulisher
Sep 21, 2026

Sionna Therapeutics (Nasdaq:SION)Stock Analysis - Simply Wall Street

Sep 21, 2026
pulisher
Sep 21, 2026

Ra Capital Management sells $21.8m in Sionna Therapeutics shares - Investing.com

Sep 21, 2026
pulisher
Sep 18, 2026

Sionna Therapeutics CMO Charlotte McKee Granted RSUs and Stock Option Repricing Announced - Kalkine Media

Sep 18, 2026
pulisher
Sep 18, 2026

Sionna (SION) cuts CFO option price to $7.18 - Stock Titan

Sep 18, 2026
pulisher
Sep 18, 2026

Sionna Therapeutics (SION) cuts CLO's option price and adds new RSUs - Stock Titan

Sep 18, 2026
pulisher
Sep 18, 2026

Sionna Therapeutics (SION) cuts CEO option exercise price - Stock Titan

Sep 18, 2026
pulisher
Sep 18, 2026

Sionna Therapeutics, Inc. (SION) Stock Analysis: Unpacking a 192% Potential Upside in the Biotech Space - DirectorsTalk Interviews

Sep 18, 2026
pulisher
Sep 14, 2026

Sionna (SION) cuts nearly half its jobs to back one cystic fibrosis program - Stock Titan

Sep 14, 2026
pulisher
Sep 10, 2026

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Sionna Therapeutics, Inc.SION - PR Newswire

Sep 10, 2026
pulisher
Sep 08, 2026

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Sionna Therapeutics, Inc.SION - FinancialContent

Sep 08, 2026
pulisher
Sep 03, 2026

Sionna Therapeutics faces securities fraud prob... - Pluang

Sep 03, 2026
pulisher
Sep 02, 2026

SIONNA THERAPEUTICS INVESTIGATION ALERT: Bragar Eagel & - GlobeNewswire

Sep 02, 2026
pulisher
Sep 02, 2026

Bronstein, Gewirtz & Grossman, LLC Encourages Sionna Therapeutics - The National Law Review

Sep 02, 2026
pulisher
Aug 31, 2026

Bronstein, Gewirtz & Grossman, LLC Initiates an Investigation into Allegations Against Sionna Therapeutics, Inc. (SION) And Encourages Shareholders to Reach Out - ACCESS Newswire

Aug 31, 2026
pulisher
Aug 31, 2026

SION INVESTIGATION: Investigation Launched into Sionna - GlobeNewswire

Aug 31, 2026
pulisher
Aug 27, 2026

Sionna Therapeutics stock plunges 91% after fai... - Pluang

Aug 27, 2026
pulisher
Aug 26, 2026

Securities Fraud Investigation Into Sionna Therapeutics, - GlobeNewswire

Aug 26, 2026
pulisher
Aug 25, 2026

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Sionna Therapeutics, Inc.SION - financialcontent.com

Aug 25, 2026
pulisher
Aug 25, 2026

Robbins LLP Reminds Investors it is Investigating Sionna Therapeutics for Potential Securities Violations - GlobeNewswire

Aug 25, 2026
pulisher
Aug 25, 2026

Securities Fraud Investigation Into Sionna Therapeutics, - GlobeNewswire

Aug 25, 2026
pulisher
Aug 21, 2026

Bronstein, Gewirtz & Grossman, LLC Is Investigating Sionna Therapeutics, Inc. (SION) And Encourages Stockholders to Connect - ACCESS Newswire

Aug 21, 2026
pulisher
Aug 21, 2026

Sionna Therapeutics, Inc. (SION) Investigation: Bronstein, Gewirtz & Grossman, LLC Encourages Stockholders to Contact the Firm to Learn More About the Investigation - ACCESS Newswire

Aug 21, 2026
pulisher
Aug 20, 2026

Sionna (SION) Earnings Reading: Profit Per Share Clears Its Benchmark in the Latest Reading; Price Move - vinanet.vn

Aug 20, 2026
pulisher
Aug 20, 2026

Vertex Pharmaceuticals' Rally Has a New Engine -- and Wall Street Thinks the Best Is Still Ahead - Yahoo Finance

Aug 20, 2026
pulisher
Aug 20, 2026

Vertex Pharmaceuticals' Rally Has a New Engine -- and Wall Street Thinks the Best Is Still Ahead - The Motley Fool

Aug 20, 2026
pulisher
Aug 20, 2026

2026-08-20 | Sionna Therapeutics, Inc. (SION) Investigation: Bronstein, Gewirtz & Grossman, LLC Encourages Stockholders to Contact the Firm to Learn More About the Investigation | NDAQ:SION | Press Release - Stockhouse

Aug 20, 2026
pulisher
Aug 20, 2026

Sionna (SION) Quarterly Figures: The Bottom-Line Figure Beats Its Comparison in the Current Update; Trading Response: The Share Price Adds 5.22% for the Current SessionTangible Book Value - vinanet.vn

Aug 20, 2026
pulisher
Aug 19, 2026

Robbins LLP Reminds Stockholders it is Investigating the Recent Stock Drop of Sionna Therapeutics - PR Newswire

Aug 19, 2026
pulisher
Aug 19, 2026

Bronstein, Gewirtz & Grossman, LLC Announces an Investigation Against Sionna Therapeutics, Inc. (SION) and Encourages Stockholders to Learn More About the Investigation - ACCESS Newswire

Aug 19, 2026
pulisher
Aug 19, 2026

Sionna shares plunge 92% after Phase 2a trial o... - Pluang

Aug 19, 2026
pulisher
Aug 19, 2026

Bronstein, Gewirtz & Grossman, LLC Announces an Investigation Aga - The National Law Review

Aug 19, 2026
pulisher
Aug 19, 2026

Sionna Therapeutics (SION) Securities Investigation NoticeLevi & Korsinsky - PR Newswire

Aug 19, 2026
pulisher
Aug 19, 2026

Investigation Launched into Sionna Therapeutics, Inc. (SION), Robbins Geller Rudman & Dowd LLP Attorneys Encourage Investors and Potential Witnesses to Contact Law Firm - Business Wire

Aug 19, 2026
pulisher
Aug 18, 2026

Securities Fraud Investigation Into Sionna Therapeutics, Inc. (SION) Announced – Shareholders Who Lost Money Urged To Contact Glancy Prongay Wolke & Rotter LLP, a Leading Securities Fraud Law Firm - WBOC TV

Aug 18, 2026
pulisher
Aug 17, 2026

Securities Fraud Investigation Into Sionna Therapeutics, Inc. (SION) Announced – Shareholders Who Lost Money Urged to Contact The Law Offices of Frank R. Cruz - FinancialContent

Aug 17, 2026
pulisher
Aug 17, 2026

Robbins LLP is Investigating the Recent Stock Drop of Sionna Therapeutics; Contact the Firm for Information - Business Wire

Aug 17, 2026
pulisher
Aug 17, 2026

Levi & Korsinsky Notifies Investors of Pending Investigation Into Securities Claims Involving Sionna Therapeutics (SION) - GlobeNewswire

Aug 17, 2026
pulisher
Aug 16, 2026

SION Investors Have Opportunity to Join Sionna Therapeutics, Inc. Fraud Investigation with SBS Law - The AI Journal

Aug 16, 2026
pulisher
Aug 16, 2026

SION Investors Have Opportunity to Join Sionna Therapeutics, Inc. Fraud Investigation with SBS Law - lincolnjournal.com

Aug 16, 2026
pulisher
Aug 16, 2026

SION INVESTOR ALERT: Investigation Launched into Sionna Therapeutics, Inc., Robbins Geller Rudman & Dowd LLP Attorneys Encourage Investors and Potential Witnesses to Contact Law Firm - The Daily Tribune News

Aug 16, 2026
pulisher
Aug 16, 2026

SION Investors Have Opportunity to Join Sionna Therapeutics, Inc. Fraud Investigation with SBS Law - Business Wire

Aug 16, 2026
pulisher
Aug 15, 2026

symbol__ Stock Quote Price and Forecast - CNN

Aug 15, 2026
pulisher
Aug 15, 2026

Sionna Therapeutics (NASDAQ:SION) Lowered to Strong Sell Rating by Wall Street Zen - MarketBeat

Aug 15, 2026
pulisher
Aug 14, 2026

SION Investor Alert: Levi & Korsinsky Notifies Investors of Investigation Into Sionna Therapeutics (SION) - Business Wire

Aug 14, 2026
pulisher
Aug 13, 2026

SION SHAREHOLDER INVESTIGATION: SueWallSt Notifies Investors of Potential Securities Claims Involving Sionna Therapeutics - PR Newswire

Aug 13, 2026
pulisher
Aug 13, 2026

Sionna Therapeutics (SION) Resets After Trial Miss, Is The Discount Now Too Deep? - Yahoo Finance

Aug 13, 2026

Sionna Therapeutics Inc Stock (SION) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Sionna Therapeutics Inc Stock (SION) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
RA Capital Healthcare Fund, L.
Director
Sep 17 '26
Proposed Sale
6.33
3,448,811
21,834,318
0
ORBIMED ADVISORS LLC
Director
Jul 07 '26
Sale
44.86
85,918
3,854,281
2,469,959
Thompson Peter A.
Director
Jul 07 '26
Sale
44.86
85,918
3,854,281
2,469,959
Fitzpatrick Jennifer
Chief Legal Officer
Jul 06 '26
Sale
43.60
10,250
446,862
0
Fitzpatrick Jennifer
Chief Legal Officer
Jul 06 '26
Option Exercise
6.11
10,250
62,628
10,250
JENNIFER FITZPATRICK
Officer
Jul 06 '26
Proposed Sale
43.99
10,250
450,898
0
ORBIMED ADVISORS LLC
Director
Jun 30 '26
Sale
45.50
115,844
5,270,902
2,555,877
Thompson Peter A.
Director
Jun 30 '26
Sale
45.50
115,844
5,270,902
2,555,877
OrbiMed Private Investments VI
Shareholder
May 29 '26
Proposed Sale
42.80
1,082,480
46,330,144
0
Thompson Peter A.
Director
May 27 '26
Sale
44.49
101
4,493
2,671,721
$10.31
price down icon 4.80%
$18.15
price down icon 7.82%
$3.32
price down icon 8.03%
$9.78
price down icon 10.36%
$7.02
price down icon 4.62%
$10.39
price down icon 8.22%
Cap:     |  Volume (24h):