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Sionna Therapeutics Inc stock is traded at $39.21, with a volume of 304.23K. It is down -4.69% in the last 24 hours and up +0.51% over the past month. Sionna Therapeutics Inc is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein to deliver clinically meaningful benefit to CF patients. CF is a progressive and life-threatening genetic disease caused by inherited mutations in the CFTR gene, which heads to insufficient CFTR function. The Company is managed as one operating segment focused on the research and development of cystic fibrosis therapies.
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Previous Close:
$41.14
Open:
$41.46
24h Volume:
304.23K
Relative Volume:
1.00
Market Cap:
$1.75B
Revenue:
-
Net Income/Loss:
-
P/E Ratio:
-
EPS:
-
Net Cash Flow:
-
1W Performance:
-10.27%
1M Performance:
+0.51%
6M Performance:
+87.88%
1Y Performance:
+0.00%
1-Day Range:
Value
$38.93
$41.56
1-Week Range:
Value
$38.93
$45.00
52-Week Range:
Value
$7.255
$45.00

Sionna Therapeutics Inc Stock (SION) Company Profile

Name
Name
Sionna Therapeutics Inc
Name
Phone
617-819-2020
Name
Address
21 HICKORY DRIVE, SUITE 500, WALTHAM
Name
Employee
48
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
SION's Discussions on Twitter

Compare SION with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SION
Sionna Therapeutics Inc
39.21 1.84B 0 0 0 0.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
452.13 115.03B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
776.31 81.12B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
400.17 52.54B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ARGX
Argen X Se Adr
839.99 51.78B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
INSM
Insmed Inc
177.12 37.12B 447.02M -1.18B -906.14M -6.1812

Sionna Therapeutics Inc Stock (SION) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-01-25 Downgrade RBC Capital Mkts Sector Perform → Underperform
Nov-19-25 Initiated BTIG Research Buy
Sep-03-25 Initiated RBC Capital Mkts Sector Perform
Sep-03-25 Initiated Raymond James Strong Buy
Mar-04-25 Initiated Guggenheim Buy
Mar-04-25 Initiated Stifel Buy
Mar-04-25 Initiated TD Cowen Buy
View All

Sionna Therapeutics Inc Stock (SION) Latest News

pulisher
Dec 30, 2025

Sionna Therapeutics Insider Sold Shares Worth $1,486,010, According to a Recent SEC Filing - marketscreener.com

Dec 30, 2025
pulisher
Dec 30, 2025

Sionna Therapeutics (NASDAQ:SION) Director Peter Thompson Sells 33,356 Shares - Defense World

Dec 30, 2025
pulisher
Dec 29, 2025

Insider Selling: Sionna Therapeutics (NASDAQ:SION) Director Sells 33,356 Shares of Stock - MarketBeat

Dec 29, 2025
pulisher
Dec 29, 2025

OrbiMed Advisors sells Sionna Therapeutics [SION] shares for $1.48m By Investing.com - Investing.com Nigeria

Dec 29, 2025
pulisher
Dec 29, 2025

OrbiMed Advisors sells Sionna Therapeutics [SION] shares for $1.48m - Investing.com

Dec 29, 2025
pulisher
Dec 29, 2025

Sionna Therapeutics (NASDAQ:SION) Sets New 12-Month HighWhat's Next? - MarketBeat

Dec 29, 2025
pulisher
Dec 29, 2025

Sionna Therapeutics (NASDAQ:SION) Broadens Clinical Research Scope - Kalkine Media

Dec 29, 2025
pulisher
Dec 25, 2025

Sionna Therapeutics: NBD1-Targeted CFTR Stabilization Strategy Positions Pipeline for Best-in-Class Efficacy and Blockbuster Upside in Cystic Fibrosis - TipRanks

Dec 25, 2025
pulisher
Dec 25, 2025

FY2025 Earnings Estimate for SION Issued By Lifesci Capital - MarketBeat

Dec 25, 2025
pulisher
Dec 24, 2025

Sionna Therapeutics (NASDAQ:SION) Now Covered by Analysts at Lifesci Capital - Defense World

Dec 24, 2025
pulisher
Dec 23, 2025

LifeSci Capital Initiates Coverage of Sionna Therapeutics (SION) with Outperform Recommendation - Nasdaq

Dec 23, 2025
pulisher
Dec 23, 2025

Sionna Therapeutics (NASDAQ:SION) Coverage Initiated by Analysts at Lifesci Capital - MarketBeat

Dec 23, 2025
pulisher
Dec 23, 2025

LifeSci Capital Initiates Coverage on Sionna Therapeutics With Outperform Rating, $60 Price Target - marketscreener.com

Dec 23, 2025
pulisher
Dec 22, 2025

Sionna Therapeutics (NASDAQ:SION) Director Sells $40,050.00 in Stock - Defense World

Dec 22, 2025
pulisher
Dec 21, 2025

Sionna Therapeutics, Inc.(NasdaqGM:SION) added to S&P Biotechnology Select Industry Index - marketscreener.com

Dec 21, 2025
pulisher
Dec 21, 2025

Sionna Therapeutics, Inc.(NasdaqGM: SION) added to NASDAQ Biotechnology Index - marketscreener.com

Dec 21, 2025
pulisher
Dec 21, 2025

Sionna Therapeutics (NASDAQ:SION) Reaches New 1-Year High – Still a Buy? - Defense World

Dec 21, 2025
pulisher
Dec 19, 2025

Peter Thompson Sells 900 Shares of Sionna Therapeutics (NASDAQ:SION) Stock - MarketBeat

Dec 19, 2025
pulisher
Dec 19, 2025

Sionna Therapeutics (NASDAQ:SION) Director Sells $38,928.75 in Stock - MarketBeat

Dec 19, 2025
pulisher
Dec 19, 2025

Shareholder OrbiMed Advisors LLC Sells 1,875 ($83.4K) Of Sionna Therapeutics Inc [SION] - TradingView — Track All Markets

Dec 19, 2025
pulisher
Dec 19, 2025

Sionna Therapeutics (NASDAQ:SION) Sets New 1-Year HighHere's What Happened - MarketBeat

Dec 19, 2025
pulisher
Dec 18, 2025

How Sionna Therapeutics Inc. stock reacts to oil pricesTrade Entry Summary & Short-Term Trading Alerts - Улправда

Dec 18, 2025
pulisher
Dec 15, 2025

Sionna Therapeutics, Inc. Rings the Nasdaq Stock Market Closing Bell - Nasdaq

Dec 15, 2025
pulisher
Dec 15, 2025

Sionna Therapeutics, Inc. Rings the Closing Bell - Nasdaq

Dec 15, 2025
pulisher
Dec 13, 2025

Braidwell LP Invests $18.77 Million in Sionna Therapeutics, Inc. $SION - MarketBeat

Dec 13, 2025
pulisher
Dec 13, 2025

Sionna Therapeutics (NASDAQ:SION) Upgraded at Wall Street Zen - MarketBeat

Dec 13, 2025
pulisher
Dec 12, 2025

Sionna Therapeutics (SION) Stock Analysis Report | Financials & Insights - Benzinga

Dec 12, 2025
pulisher
Dec 12, 2025

Sionna Therapeutics, Inc. (NASDAQ:SION) Receives Average Recommendation of “Moderate Buy” from Analysts - Defense World

Dec 12, 2025
pulisher
Dec 12, 2025

Sionna Therapeutics, Inc. (NASDAQ:SION) Receives Average Recommendation of "Moderate Buy" from Analysts - MarketBeat

Dec 12, 2025
pulisher
Dec 09, 2025

Sionna Therapeutics chief legal officer sells $415,330 in stock By Investing.com - Investing.com Canada

Dec 09, 2025
pulisher
Dec 09, 2025

Sionna Therapeutics chief legal officer sells $415,330 in stock - Investing.com India

Dec 09, 2025
pulisher
Dec 09, 2025

Sionna Therapeutics Insider Sold Shares Worth $415,330, According to a Recent SEC Filing - marketscreener.com

Dec 09, 2025
pulisher
Dec 09, 2025

Officer Fitzpatrick Sells 10,250 ($415.3K) Of Sionna Therapeutics Inc [SION] - TradingView — Track All Markets

Dec 09, 2025
pulisher
Dec 08, 2025

Bosun Asset Management LLC Invests $295,000 in Sionna Therapeutics, Inc. $SION - Defense World

Dec 08, 2025
pulisher
Dec 05, 2025

Officer Fitzpatrick Files To Sell 10,250 Of Sionna Therapeutics Inc [SION] - TradingView

Dec 05, 2025
pulisher
Dec 05, 2025

Sionna Therapeutics, Inc. $SION Shares Acquired by Prudential Financial Inc. - MarketBeat

Dec 05, 2025
pulisher
Dec 04, 2025

Sionna Therapeutics (NASDAQ:SION) Shares Up 11.4%What's Next? - MarketBeat

Dec 04, 2025
pulisher
Dec 04, 2025

Sionna Therapeutics Valuation Topping $2 Billion Is 'Too Optimistic', RBC Says - marketscreener.com

Dec 04, 2025
pulisher
Dec 04, 2025

Transcript : Sionna Therapeutics, Inc. Presents at Citi Annual Global Healthcare Conference 2025, Dec-04-2025 09 - marketscreener.com

Dec 04, 2025
pulisher
Dec 04, 2025

Why Sionna Therapeutics Inc. stock remains resilient2025 Short Interest & Long-Term Growth Portfolio Plans - Newser

Dec 04, 2025
pulisher
Dec 03, 2025

Will Sionna Therapeutics Inc. stock gain from government policies - Newser

Dec 03, 2025
pulisher
Dec 03, 2025

Sionna Therapeutics, Inc. $SION Shares Purchased by JPMorgan Chase & Co. - MarketBeat

Dec 03, 2025
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Dec 02, 2025

Sionna Therapeutics (NASDAQ:SION) Shares Gap DownHere's What Happened - MarketBeat

Dec 02, 2025
pulisher
Dec 02, 2025

Views of Wall Street’s Leading Experts on Sionna Therapeutics Inc - Setenews

Dec 02, 2025
pulisher
Dec 02, 2025

Royal Bank Of Canada Reiterates "Underperform" Rating for Sionna Therapeutics (NASDAQ:SION) - MarketBeat

Dec 02, 2025
pulisher
Dec 02, 2025

Is Sionna Therapeutics Inc. stock affected by interest rate hikesGold Moves & Precise Entry and Exit Recommendations - Newser

Dec 02, 2025
pulisher
Dec 01, 2025

Sionna Therapeutics Shares Lower After RBC Downgrade - marketscreener.com

Dec 01, 2025
pulisher
Dec 01, 2025

Sionna Therapeutics stock tumbles after RBC downgrade By Investing.com - Investing.com Canada

Dec 01, 2025
pulisher
Dec 01, 2025

SION Downgraded by RBC Capital: Today's Analyst Rating | SION St - GuruFocus

Dec 01, 2025

Sionna Therapeutics Inc Stock (SION) Financials Data

There is no financial data for Sionna Therapeutics Inc (SION). Check out other stocks for more information.

Revenue

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Net Income

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Cash Flow

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EPS

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Sionna Therapeutics Inc Stock (SION) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Thompson Peter A.
Director
Dec 24 '25
Sale
44.55
33,356
1,486,010
3,561,655
ORBIMED ADVISORS LLC
Director
Dec 17 '25
Sale
44.50
900
40,050
3,595,986
ORBIMED ADVISORS LLC
Director
Dec 19 '25
Sale
44.49
875
38,929
3,595,011
ORBIMED ADVISORS LLC
Director
Dec 18 '25
Sale
44.49
100
4,449
3,595,886
Thompson Peter A.
Director
Dec 17 '25
Sale
44.50
900
40,050
3,595,986
Thompson Peter A.
Director
Dec 19 '25
Sale
44.49
875
38,929
3,595,011
Thompson Peter A.
Director
Dec 18 '25
Sale
44.49
100
4,449
3,595,886
Fitzpatrick Jennifer
Chief Legal Officer
Dec 05 '25
Option Exercise
6.11
10,250
62,628
10,250
Fitzpatrick Jennifer
Chief Legal Officer
Dec 05 '25
Sale
40.52
10,250
415,330
0
$38.86
price up icon 0.57%
$31.82
price up icon 3.31%
$101.42
price up icon 2.68%
$96.69
price up icon 1.57%
biotechnology ONC
$311.02
price up icon 2.37%
$177.12
price up icon 1.77%
Cap:     |  Volume (24h):