37.64
price up icon3.04%   1.11
after-market After Hours: 37.64
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Sionna Therapeutics Inc stock is traded at $37.64, with a volume of 199.77K. It is up +3.04% in the last 24 hours and up +3.58% over the past month. Sionna Therapeutics Inc is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein to deliver clinically meaningful benefit to CF patients. CF is a progressive and life-threatening genetic disease caused by inherited mutations in the CFTR gene, which heads to insufficient CFTR function. The Company is managed as one operating segment focused on the research and development of cystic fibrosis therapies.
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Previous Close:
$36.53
Open:
$36.3
24h Volume:
199.77K
Relative Volume:
0.66
Market Cap:
$1.68B
Revenue:
-
Net Income/Loss:
-
P/E Ratio:
-
EPS:
-
Net Cash Flow:
-
1W Performance:
+6.78%
1M Performance:
+3.58%
6M Performance:
+79.32%
1Y Performance:
+89.53%
1-Day Range:
Value
$36.07
$38.86
1-Week Range:
Value
$34.87
$38.91
52-Week Range:
Value
$7.255
$45.00

Sionna Therapeutics Inc Stock (SION) Company Profile

Name
Name
Sionna Therapeutics Inc
Name
Phone
617-819-2020
Name
Address
21 HICKORY DRIVE, SUITE 500, WALTHAM
Name
Employee
48
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
SION's Discussions on Twitter

Compare SION vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SION
Sionna Therapeutics Inc
37.64 1.63B 0 0 0 0.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
465.02 117.03B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
783.65 82.35B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
833.54 51.64B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
308.48 42.58B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ONC
Beone Medicines Ltd Adr
346.42 38.87B 4.98B 69.60M 525.67M 0.5198

Sionna Therapeutics Inc Stock (SION) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-01-25 Downgrade RBC Capital Mkts Sector Perform → Underperform
Nov-19-25 Initiated BTIG Research Buy
Sep-03-25 Initiated RBC Capital Mkts Sector Perform
Sep-03-25 Initiated Raymond James Strong Buy
Mar-04-25 Initiated Guggenheim Buy
Mar-04-25 Initiated Stifel Buy
Mar-04-25 Initiated TD Cowen Buy
View All

Sionna Therapeutics Inc Stock (SION) Latest News

pulisher
Feb 11, 2026

SION: NBD1 stabilizer programs target major CF mutations, with pivotal data expected mid-2026 - TradingView

Feb 11, 2026
pulisher
Feb 09, 2026

What’s the MACD signal for Sionna Therapeutics Inc.July 2025 Outlook & Risk Adjusted Buy/Sell Alerts - mfd.ru

Feb 09, 2026
pulisher
Feb 08, 2026

Volume Recap: Should you avoid Sionna Therapeutics Inc stock right nowEarnings Miss & Growth-Oriented Investment Plans - baoquankhu1.vn

Feb 08, 2026
pulisher
Feb 06, 2026

Orbimed Advisors Llc Sells 29,063 Shares of Sionna Therapeutics (NASDAQ:SION) Stock - Defense World

Feb 06, 2026
pulisher
Feb 06, 2026

Sionna Therapeutics (NASDAQ:SION) Shares Down 14.6% on Insider Selling - Defense World

Feb 06, 2026
pulisher
Feb 05, 2026

Sionna Therapeutics (NASDAQ:SION) Trading Down 14.6% Following Insider Selling - MarketBeat

Feb 05, 2026
pulisher
Feb 05, 2026

OrbiMed Advisors LLC sells Sionna Therapeutics (SION) stock worth $1.37m - Investing.com

Feb 05, 2026
pulisher
Feb 05, 2026

OrbiMed Advisors LLC sells Sionna Therapeutics (SION) stock worth $1.37m By Investing.com - Investing.com South Africa

Feb 05, 2026
pulisher
Feb 05, 2026

Thompson Peter a. sells Sionna Therapeutics (SION) shares for $1.37m By Investing.com - Investing.com South Africa

Feb 05, 2026
pulisher
Feb 05, 2026

Thompson Peter a. sells Sionna Therapeutics (SION) shares for $1.37m - Investing.com India

Feb 05, 2026
pulisher
Feb 04, 2026

Sionna Therapeutics (NASDAQ:SION) Director Orbimed Advisors Llc Sells 29,063 Shares - MarketBeat

Feb 04, 2026
pulisher
Feb 04, 2026

Sionna Therapeutics to Present at the Guggenheim Securities Emerging Outlook: Biotech Summit 2026 - markets.businessinsider.com

Feb 04, 2026
pulisher
Feb 04, 2026

Sionna Therapeutics (NASDAQ:SION) Director Sells $84,237.30 in Stock - MarketBeat

Feb 04, 2026
pulisher
Jan 31, 2026

Support Test: Whats the outlook for Sionna Therapeutics Incs sectorTrade Risk Summary & Smart Allocation Stock Reports - baoquankhu1.vn

Jan 31, 2026
pulisher
Jan 31, 2026

Sionna Therapeutics, Inc. (NASDAQ:SION) Receives Average Rating of "Moderate Buy" from Analysts - MarketBeat

Jan 31, 2026
pulisher
Jan 30, 2026

TPG GP A, LLC Reduces Stake in Sionna Therapeutics Inc - GuruFocus

Jan 30, 2026
pulisher
Jan 30, 2026

Sionna Therapeutics, Inc. (SION) Stock Analysis: Biotech’s Promising Prospects with 5.7% Upside Potential - DirectorsTalk Interviews

Jan 30, 2026
pulisher
Jan 27, 2026

Sionna Therapeutics (SION) 10% owners sell $10 million in stock By Investing.com - Investing.com South Africa

Jan 27, 2026
pulisher
Jan 26, 2026

Major Stake Unloaded in Sionna Therapeutics Sparks Fresh Market Buzz - TipRanks

Jan 26, 2026
pulisher
Jan 26, 2026

Tpg Gp A, Llc Sells 250,000 Shares of Sionna Therapeutics (NASDAQ:SION) Stock - MarketBeat

Jan 26, 2026
pulisher
Jan 26, 2026

Sionna Therapeutics (SION) 10% owners sell $10 million in stock - Investing.com

Jan 26, 2026
pulisher
Jan 26, 2026

Sionna Therapeutics (NASDAQ:SION) Shares Gap DownHere's Why - MarketBeat

Jan 26, 2026
pulisher
Jan 23, 2026

Sionna Therapeutics, Inc. (SION) Stock Analysis: Exploring a 7.39% Potential Upside in Biotech Innovation - DirectorsTalk Interviews

Jan 23, 2026
pulisher
Jan 21, 2026

Aug Sentiment: Should you avoid Sionna Therapeutics Inc stock right now - baoquankhu1.vn

Jan 21, 2026
pulisher
Jan 15, 2026

Sionna Therapeutics Chief Legal Officer Caps Off Strong 2025 with Sale of Over 10,000 Shares - AOL.com

Jan 15, 2026
pulisher
Jan 14, 2026

Sionna Therapeutics (NASDAQ:SION) Stock Price Up 8.1%Here's Why - MarketBeat

Jan 14, 2026
pulisher
Jan 14, 2026

Multiple Shots on Goal in Cystic Fibrosis: Sionna’s NBD1-Targeted Pipeline and 2026 Clinical Readouts Drive Buy Thesis and $58 DCF-Based Target - TipRanks

Jan 14, 2026
pulisher
Jan 14, 2026

BTIG Research Reiterates Buy Rating for Sionna Therapeutics (NASDAQ:SION) - MarketBeat

Jan 14, 2026
pulisher
Jan 13, 2026

SION: Advancing NBD1 stabilizers to transform CF care, with key data expected mid-2026 - TradingView

Jan 13, 2026
pulisher
Jan 13, 2026

SION: First-in-class NBD1 stabilizers target full CFTR correction, with pivotal data expected mid-2026 - TradingView — Track All Markets

Jan 13, 2026
pulisher
Jan 12, 2026

Sionna Therapeutics (NASDAQ:SION) Stock Price Down 10.1%Here's What Happened - MarketBeat

Jan 12, 2026
pulisher
Jan 12, 2026

Assessing Sionna Therapeutics (SION) Valuation After Recent Share Price Swings And Premium P/B Multiple - Yahoo Finance

Jan 12, 2026
pulisher
Jan 10, 2026

Sionna Therapeutics Advances Cystic Fibrosis Treatment with New Study - MSN

Jan 10, 2026
pulisher
Jan 09, 2026

Sionna Therapeutics, Inc. (SION) Stock Analysis: A 27.73% Potential Upside in the Biotech Sector - DirectorsTalk Interviews

Jan 09, 2026
pulisher
Jan 09, 2026

Assessing Sionna Therapeutics (SION) Valuation After A Sharp Share Price Move And Elevated Price To Book Ratio - Sahm

Jan 09, 2026
pulisher
Jan 08, 2026

Market Recap: How Sionna Therapeutics Inc. stock compares to industry benchmarks2025 Sector Review & Trade Opportunity Analysis - Улправда

Jan 08, 2026
pulisher
Jan 08, 2026

Is Sionna Therapeutics Inc. stock positioned for long term growthPortfolio Value Summary & Smart Money Movement Tracker - Улправда

Jan 08, 2026
pulisher
Jan 07, 2026

Sionna Therapeutics (NASDAQ:SION) Trading Up 7.7%Here's Why - MarketBeat

Jan 07, 2026
pulisher
Jan 07, 2026

Sionna Therapeutics, Inc. (NASDAQ:SION) Receives Average Recommendation of “Moderate Buy” from Analysts - Defense World

Jan 07, 2026
pulisher
Jan 06, 2026

Sionna Therapeutics (NASDAQ:SION) Shares Down 7.5%What's Next? - MarketBeat

Jan 06, 2026
pulisher
Jan 06, 2026

Sionna Therapeutics, Inc. (NASDAQ:SION) Receives Average Recommendation of "Moderate Buy" from Analysts - MarketBeat

Jan 06, 2026
pulisher
Jan 05, 2026

Orbimed Advisors LLC Reduces Stake in Sionna Therapeutics Inc - GuruFocus

Jan 05, 2026
pulisher
Jan 05, 2026

Raymond James raises Sionna Therapeutics stock price target on CF drug potential - Investing.com Canada

Jan 05, 2026
pulisher
Jan 05, 2026

Sionna Therapeutics to Present at the 44th Annual J.P. Morgan Healthcare Conference - The Manila Times

Jan 05, 2026
pulisher
Jan 04, 2026

A Sionna Therapeutics (SION) Insider Sold 33,000 Shares for $1.5 Million - AOL.com

Jan 04, 2026
pulisher
Jan 03, 2026

A Sionna Therapeutics (SION) Insider Sold 33,000 Shares for $1.5 Million - The Motley Fool

Jan 03, 2026
pulisher
Dec 30, 2025

Sionna Therapeutics Insider Sold Shares Worth $1,486,010, According to a Recent SEC Filing - marketscreener.com

Dec 30, 2025

Sionna Therapeutics Inc Stock (SION) Financials Data

There is no financial data for Sionna Therapeutics Inc (SION). Check out other stocks for more information.

Revenue

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Net Income

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Cash Flow

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EPS

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Sionna Therapeutics Inc Stock (SION) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Thompson Peter A.
Director
Feb 02 '26
Sale
44.57
1,890
84,237
3,559,765
ORBIMED ADVISORS LLC
Director
Feb 03 '26
Sale
44.58
29,063
1,295,629
3,530,702
ORBIMED ADVISORS LLC
Director
Feb 02 '26
Sale
44.57
1,890
84,237
3,559,765
TPG GP A, LLC
10% Owner
Jan 22 '26
Sale
40.00
250,000
10,000,000
6,494,962
$44.80
price up icon 1.24%
$26.75
price down icon 0.19%
$100.75
price up icon 1.93%
$105.76
price down icon 3.31%
$146.17
price down icon 1.52%
biotechnology ONC
$346.42
price down icon 1.38%
Cap:     |  Volume (24h):