25.64
price down icon3.79%   -1.035
 
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Septerna Inc stock is traded at $25.64, with a volume of 62,834. It is down -3.79% in the last 24 hours and down -9.10% over the past month. Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
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Previous Close:
$26.67
Open:
$26.64
24h Volume:
62,834
Relative Volume:
0.21
Market Cap:
$1.15B
Revenue:
-
Net Income/Loss:
-
P/E Ratio:
-
EPS:
-
Net Cash Flow:
-
1W Performance:
-1.57%
1M Performance:
-9.10%
6M Performance:
+89.65%
1Y Performance:
+39.61%
1-Day Range:
Value
$25.35
$26.82
1-Week Range:
Value
$25.35
$27.95
52-Week Range:
Value
$4.17
$30.50

Septerna Inc Stock (SEPN) Company Profile

Name
Name
Septerna Inc
Name
Phone
650-338-3533
Name
Address
250 EAST GRAND AVENUE, SUITE 65, SOUTH SAN FRANCISCO
Name
Employee
75
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
SEPN's Discussions on Twitter

Compare SEPN with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SEPN
Septerna Inc
25.64 1.19B 0 0 0 0.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
463.95 118.58B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
749.78 79.40B 14.25B 4.58B 3.88B 41.77
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ARGX
Argen X Se Adr
811.57 51.18B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
360.78 48.88B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ONC
Beone Medicines Ltd Adr
339.19 37.49B 4.98B 69.59M 525.67M 0.5197

Septerna Inc Stock (SEPN) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-19-25 Initiated Raymond James Strong Buy
Dec-15-25 Initiated Truist Buy
Nov-14-25 Upgrade Wells Fargo Equal Weight → Overweight
Jun-23-25 Initiated H.C. Wainwright Buy
Feb-18-25 Downgrade Wells Fargo Overweight → Equal Weight
Nov-19-24 Initiated Cantor Fitzgerald Overweight
Nov-19-24 Initiated JP Morgan Overweight
Nov-19-24 Initiated TD Cowen Buy
Nov-19-24 Initiated Wells Fargo Overweight
View All

Septerna Inc Stock (SEPN) Latest News

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01:14 AM

HC Wainwright Analysts Lower Earnings Estimates for Septerna - Defense World

01:14 AM
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Jan 22, 2026

HC Wainwright Issues Negative Forecast for Septerna Earnings - MarketBeat

Jan 22, 2026
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Jan 21, 2026

Is Septerna (SEPN) Quietly Building an IP Moat with Its New Chief Legal Officer Hire? - simplywall.st

Jan 21, 2026
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Jan 20, 2026

Septerna stock price target raised to $35 from $30 at H.C. Wainwright - Investing.com Canada

Jan 20, 2026
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Jan 20, 2026

The Analyst Verdict: Septerna In The Eyes Of 6 Experts - Benzinga

Jan 20, 2026
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Jan 20, 2026

Septerna: Advancing GPCR Pipeline and De-Risked Valuation Support Upgraded Buy Rating and $35 Target - TipRanks

Jan 20, 2026
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Jan 20, 2026

SEPN: HC Wainwright & Co. Updates Price Target to $35 | SEPN Sto - GuruFocus

Jan 20, 2026
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Jan 17, 2026

Aug Reactions: Does Septerna Inc have a sustainable dividendInflation Watch & Real-Time Market Sentiment Alerts - baoquankhu1.vn

Jan 17, 2026
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Jan 13, 2026

Septerna (NASDAQ:SEPN) Shares Up 7.5%Still a Buy? - MarketBeat

Jan 13, 2026
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Jan 12, 2026

Septerna to Present GPCR Pipeline Updates at JPM Conference - TipRanks

Jan 12, 2026
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Jan 12, 2026

Septerna, Inc. Announces Key Developments at J.P. Morgan Healthcare Conference - TradingView — Track All Markets

Jan 12, 2026
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Jan 10, 2026

Assessing Septerna (SEPN) Valuation After Recent Share Price Pullback And One Year 40.63% Return - Yahoo Finance

Jan 10, 2026
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Jan 10, 2026

Septerna (NASDAQ:SEPN) Downgraded to “Buy” Rating by Wall Street Zen - Defense World

Jan 10, 2026
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Jan 09, 2026

Septerna, Inc. (SEPN) Stock Analysis: Unraveling a 28.76% Potential Upside in Biotechnology - DirectorsTalk Interviews

Jan 09, 2026
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Jan 09, 2026

Septerna, Inc. (NASDAQ:SEPN) Given Consensus Rating of "Moderate Buy" by Brokerages - MarketBeat

Jan 09, 2026
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Jan 08, 2026

Will Septerna Inc. stock benefit from sector rotationMarket Growth Summary & AI Enhanced Market Trend Forecasts - Улправда

Jan 08, 2026
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Jan 08, 2026

Why retail investors favor Septerna Inc. stockEarnings Risk Summary & Low Drawdown Trading Techniques - Улправда

Jan 08, 2026
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Jan 08, 2026

Septerna Appoints Mark Wilson as Chief Legal Officer - MarketScreener

Jan 08, 2026
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Jan 08, 2026

What Wall Street predicts for Septerna Inc. stock priceMarket Growth Summary & Intraday High Probability Setup Alerts - ulpravda.ru

Jan 08, 2026
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Jan 08, 2026

Septerna appoints Mark Wilson as chief legal officer By Investing.com - Investing.com South Africa

Jan 08, 2026
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Jan 08, 2026

Septerna appoints Mark Wilson as chief legal officer - Investing.com

Jan 08, 2026
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Jan 08, 2026

Septerna, Inc. Expands Leadership with New Chief Legal Officer - TradingView — Track All Markets

Jan 08, 2026
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Jan 08, 2026

Septerna Expands Leadership with Appointment of Industry Veteran Mark A. Wilson as Chief Legal Officer - The Manila Times

Jan 08, 2026
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Jan 05, 2026

Septerna (NASDAQ:SEPN) Stock Price Down 6.3%What's Next? - MarketBeat

Jan 05, 2026
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Dec 29, 2025

What analysts say about Septerna Inc stockDividend Yield Trends & AI-Based Predictions Available Free - earlytimes.in

Dec 29, 2025
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Dec 23, 2025

Jones Trading initiates coverage of Septerna (SEPN) with buy recommendation - MSN

Dec 23, 2025
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Dec 23, 2025

Jones Trading Initiates Coverage of Septerna (SEPN) with Buy Recommendation - Nasdaq

Dec 23, 2025
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Dec 23, 2025

Septerna stock initiated with Buy rating at Jones Trading on GPCR pipeline By Investing.com - Investing.com South Africa

Dec 23, 2025
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Dec 23, 2025

Septerna stock initiated with Buy rating at Jones Trading on GPCR pipeline - Investing.com Nigeria

Dec 23, 2025
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Dec 23, 2025

Septerna (NASDAQ:SEPN) Coverage Initiated at Jones Trading - MarketBeat

Dec 23, 2025
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Dec 22, 2025

Septerna (SEPN): Valuation Check After Raymond James Buy Rating and S&P Pharma Index Inclusion - Sahm

Dec 22, 2025
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Dec 21, 2025

Septerna, Inc.(NasdaqGM: SEPN) added to S&P Pharmaceuticals Select Industry Index - marketscreener.com

Dec 21, 2025
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Dec 21, 2025

Septerna, Inc.(NasdaqGM: SEPN) added to NASDAQ Biotechnology Index - marketscreener.com

Dec 21, 2025
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Dec 21, 2025

Septerna’s SEP-631 Study: A Potential Game-Changer in Pharmaceutical Research - MSN

Dec 21, 2025
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Dec 21, 2025

Is New Coverage of Septerna (SEPN) Quietly Reframing Its GPCR Platform’s Risk‑Reward Profile? - simplywall.st

Dec 21, 2025
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Dec 21, 2025

Septerna (NASDAQ:SEPN) Coverage Initiated at Raymond James Financial - Defense World

Dec 21, 2025
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Dec 20, 2025

Septerna (NASDAQ:SEPN) Raised to "Strong-Buy" at Raymond James Financial - MarketBeat

Dec 20, 2025
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Dec 20, 2025

Wall Street Zen Upgrades Septerna (NASDAQ:SEPN) to "Strong-Buy" - MarketBeat

Dec 20, 2025
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Dec 20, 2025

Wall Street Zen Upgrades Septerna (NASDAQ:SEPN) to “Strong-Buy” - Defense World

Dec 20, 2025
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Dec 20, 2025

Why Septerna Inc. stock could be next big winner2025 AllTime Highs & Risk Controlled Stock Pick Alerts - Улправда

Dec 20, 2025
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Dec 19, 2025

Septerna Inc stock hits all-time high at 29.79 USD By Investing.com - Investing.com Nigeria

Dec 19, 2025
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Dec 19, 2025

Septerna (NASDAQ:SEPN) Reaches New 12-Month HighShould You Buy? - MarketBeat

Dec 19, 2025
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Dec 19, 2025

Septerna Inc stock hits all-time high at 29.79 USD - Investing.com

Dec 19, 2025
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Dec 19, 2025

Raymond James Initiates Coverage of Septerna (SEPN) with Strong Buy Recommendation - Nasdaq

Dec 19, 2025
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Dec 19, 2025

Raymond James initiates Septerna stock with Strong Buy rating, $38 target - Investing.com Australia

Dec 19, 2025
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Dec 19, 2025

Raymond James Initiates Coverage on Septerna With Strong Buy Rating, $38 Price Target - marketscreener.com

Dec 19, 2025
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Dec 19, 2025

Raymond James initiates Septerna stock with Strong Buy rating, $38 target By Investing.com - Investing.com India

Dec 19, 2025
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Dec 19, 2025

With Septerna Stock Surging, Have You Considered The Downside? - Trefis

Dec 19, 2025
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Dec 19, 2025

Why Septerna Inc. stock is a must watch in 20252025 Sector Review & Risk Managed Investment Strategies - DonanımHaber

Dec 19, 2025

Septerna Inc Stock (SEPN) Financials Data

There is no financial data for Septerna Inc (SEPN). Check out other stocks for more information.

Revenue

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Net Income

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Cash Flow

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EPS

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$100.60
price down icon 4.38%
$33.77
price up icon 1.95%
$118.82
price up icon 0.01%
$116.03
price down icon 2.22%
$155.69
price down icon 3.02%
biotechnology ONC
$338.76
price down icon 0.05%
Cap:     |  Volume (24h):