25.76
price down icon2.20%   -0.58
after-market After Hours: 25.31 -0.45 -1.75%
loading
Septerna Inc stock is traded at $25.76, with a volume of 170.96K. It is down -2.20% in the last 24 hours and up +3.54% over the past month. Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
See More
Previous Close:
$26.34
Open:
$26.7
24h Volume:
170.96K
Relative Volume:
0.55
Market Cap:
$1.15B
Revenue:
-
Net Income/Loss:
-
P/E Ratio:
-
EPS:
-
Net Cash Flow:
-
1W Performance:
+5.40%
1M Performance:
+3.54%
6M Performance:
+130.00%
1Y Performance:
+127.56%
1-Day Range:
Value
$25.22
$26.70
1-Week Range:
Value
$24.13
$27.31
52-Week Range:
Value
$4.17
$30.50

Septerna Inc Stock (SEPN) Company Profile

Name
Name
Septerna Inc
Name
Phone
650-338-3533
Name
Address
250 EAST GRAND AVENUE, SUITE 65, SOUTH SAN FRANCISCO
Name
Employee
75
Name
Twitter
Name
Next Earnings Date
Name
Latest SEC Filings
Name
SEPN's Discussions on Twitter

Compare SEPN vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SEPN
Septerna Inc
25.76 1.18B 0 0 0 0.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
465.02 117.03B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
783.65 82.35B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
833.54 51.64B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
308.48 42.58B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ONC
Beone Medicines Ltd Adr
346.42 38.87B 4.98B 69.60M 525.67M 0.5198

Septerna Inc Stock (SEPN) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-19-25 Initiated Raymond James Strong Buy
Dec-15-25 Initiated Truist Buy
Nov-14-25 Upgrade Wells Fargo Equal Weight → Overweight
Jun-23-25 Initiated H.C. Wainwright Buy
Feb-18-25 Downgrade Wells Fargo Overweight → Equal Weight
Nov-19-24 Initiated Cantor Fitzgerald Overweight
Nov-19-24 Initiated JP Morgan Overweight
Nov-19-24 Initiated TD Cowen Buy
Nov-19-24 Initiated Wells Fargo Overweight
View All

Septerna Inc Stock (SEPN) Latest News

pulisher
Feb 11, 2026

How Early SEP-631 Data at AAAAI 2026 Will Impact Septerna (SEPN) Investors - simplywall.st

Feb 11, 2026
pulisher
Feb 11, 2026

Septerna to present phase 1 data for SEP-631 at AAAAI meeting - Investing.com Canada

Feb 11, 2026
pulisher
Feb 10, 2026

Septerna Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) - The Manila Times

Feb 10, 2026
pulisher
Feb 10, 2026

Viatris Septerna BIO Takeda name new legal chiefs - BioXconomy

Feb 10, 2026
pulisher
Feb 10, 2026

Early trial tests oral therapy for mast cell diseases at 2026 allergy meeting - Stock Titan

Feb 10, 2026
pulisher
Feb 07, 2026

Profit Recap: How do insiders feel about AutoZone IncJuly 2025 Decliners & Accurate Entry and Exit Point Alerts - baoquankhu1.vn

Feb 07, 2026
pulisher
Feb 07, 2026

Aug Breakouts: Is Septerna Inc a cyclical or defensive stockWeekly Earnings Recap & AI Driven Stock Reports - baoquankhu1.vn

Feb 07, 2026
pulisher
Feb 06, 2026

Death Cross: Will Septerna Inc stock go up in YEAR2025 Macro Impact & Smart Swing Trading Alerts - baoquankhu1.vn

Feb 06, 2026
pulisher
Feb 03, 2026

Septerna, Inc. (NASDAQ:SEPN) Receives Consensus Recommendation of "Moderate Buy" from Analysts - MarketBeat

Feb 03, 2026
pulisher
Feb 03, 2026

Septerna, Inc. (NASDAQ:SEPN) Receives Consensus Recommendation of “Moderate Buy” from Analysts - Defense World

Feb 03, 2026
pulisher
Feb 03, 2026

Travel Stocks: Is Septerna Inc forming a bullish divergenceWeekly Profit Recap & Daily Price Action Insights - baoquankhu1.vn

Feb 03, 2026
pulisher
Feb 02, 2026

Septerna (NASDAQ:SEPN) Shares Up 7.9%Still a Buy? - MarketBeat

Feb 02, 2026
pulisher
Feb 01, 2026

Short Interest in Septerna, Inc. (NASDAQ:SEPN) Increases By 36.0% - MarketBeat

Feb 01, 2026
pulisher
Jan 30, 2026

Septerna, Inc. (SEPN) Investor Outlook: 42% Potential Upside Amidst Breakthrough Growth In Revenue - DirectorsTalk Interviews

Jan 30, 2026
pulisher
Jan 23, 2026

HC Wainwright Analysts Lower Earnings Estimates for Septerna - Defense World

Jan 23, 2026
pulisher
Jan 22, 2026

Septerna: Advancing GPCR Pipeline and De-Risked Valuation Support Upgraded Buy Rating and $35 Target - TipRanks

Jan 22, 2026
pulisher
Jan 22, 2026

HC Wainwright Issues Negative Forecast for Septerna Earnings - MarketBeat

Jan 22, 2026
pulisher
Jan 22, 2026

Is Septerna (SEPN) Quietly Building an IP Moat with Its New Chief Legal Officer Hire? - simplywall.st

Jan 22, 2026
pulisher
Jan 21, 2026

SEPN: HC Wainwright & Co. Updates Price Target to $35 | SEPN Sto - GuruFocus

Jan 21, 2026
pulisher
Jan 20, 2026

Septerna stock price target raised to $35 from $30 at H.C. Wainwright - Investing.com Nigeria

Jan 20, 2026
pulisher
Jan 20, 2026

The Analyst Verdict: Septerna In The Eyes Of 6 Experts - Benzinga

Jan 20, 2026
pulisher
Jan 17, 2026

Aug Reactions: Does Septerna Inc have a sustainable dividendInflation Watch & Real-Time Market Sentiment Alerts - baoquankhu1.vn

Jan 17, 2026
pulisher
Jan 13, 2026

Septerna (NASDAQ:SEPN) Shares Up 7.5%Still a Buy? - MarketBeat

Jan 13, 2026
pulisher
Jan 12, 2026

Septerna to Present GPCR Pipeline Updates at JPM Conference - TipRanks

Jan 12, 2026
pulisher
Jan 12, 2026

Septerna, Inc. Announces Key Developments at J.P. Morgan Healthcare Conference - TradingView — Track All Markets

Jan 12, 2026
pulisher
Jan 10, 2026

Assessing Septerna (SEPN) Valuation After Recent Share Price Pullback And One Year 40.63% Return - Yahoo Finance

Jan 10, 2026
pulisher
Jan 10, 2026

Septerna (NASDAQ:SEPN) Downgraded to “Buy” Rating by Wall Street Zen - Defense World

Jan 10, 2026
pulisher
Jan 09, 2026

Septerna, Inc. (SEPN) Stock Analysis: Unraveling a 28.76% Potential Upside in Biotechnology - DirectorsTalk Interviews

Jan 09, 2026
pulisher
Jan 09, 2026

Septerna, Inc. (NASDAQ:SEPN) Given Consensus Rating of "Moderate Buy" by Brokerages - MarketBeat

Jan 09, 2026
pulisher
Jan 09, 2026

Septerna Appoints Mark Wilson as Chief Legal Officer - The Globe and Mail

Jan 09, 2026
pulisher
Jan 08, 2026

Will Septerna Inc. stock benefit from sector rotationMarket Growth Summary & AI Enhanced Market Trend Forecasts - Улправда

Jan 08, 2026
pulisher
Jan 08, 2026

Why retail investors favor Septerna Inc. stockEarnings Risk Summary & Low Drawdown Trading Techniques - Улправда

Jan 08, 2026
pulisher
Jan 08, 2026

What Wall Street predicts for Septerna Inc. stock priceMarket Growth Summary & Intraday High Probability Setup Alerts - ulpravda.ru

Jan 08, 2026
pulisher
Jan 08, 2026

Septerna appoints Mark Wilson as chief legal officer By Investing.com - Investing.com South Africa

Jan 08, 2026
pulisher
Jan 08, 2026

Septerna appoints Mark Wilson as chief legal officer - Investing.com

Jan 08, 2026
pulisher
Jan 08, 2026

Septerna, Inc. Expands Leadership with New Chief Legal Officer - TradingView — Track All Markets

Jan 08, 2026
pulisher
Jan 08, 2026

Septerna Expands Leadership with Appointment of Industry Veteran Mark A. Wilson as Chief Legal Officer - The Manila Times

Jan 08, 2026
pulisher
Jan 05, 2026

Septerna (NASDAQ:SEPN) Stock Price Down 6.3%What's Next? - MarketBeat

Jan 05, 2026
pulisher
Jan 02, 2026

Septerna, Inc. (SEPN) Stock Analysis: Unveiling a Potential 18.88% Upside with Groundbreaking Biotech Innovations - DirectorsTalk Interviews

Jan 02, 2026
pulisher
Dec 29, 2025

What analysts say about Septerna Inc stockDividend Yield Trends & AI-Based Predictions Available Free - earlytimes.in

Dec 29, 2025
pulisher
Dec 23, 2025

Jones Trading initiates coverage of Septerna (SEPN) with buy recommendation - MSN

Dec 23, 2025
pulisher
Dec 23, 2025

Jones Trading Initiates Coverage of Septerna (SEPN) with Buy Recommendation - Nasdaq

Dec 23, 2025
pulisher
Dec 23, 2025

Septerna stock initiated with Buy rating at Jones Trading on GPCR pipeline By Investing.com - Investing.com South Africa

Dec 23, 2025
pulisher
Dec 23, 2025

Septerna stock initiated with Buy rating at Jones Trading on GPCR pipeline - Investing.com Nigeria

Dec 23, 2025
pulisher
Dec 23, 2025

Septerna (NASDAQ:SEPN) Coverage Initiated at Jones Trading - MarketBeat

Dec 23, 2025
pulisher
Dec 22, 2025

Septerna (SEPN): Valuation Check After Raymond James Buy Rating and S&P Pharma Index Inclusion - Sahm

Dec 22, 2025
pulisher
Dec 21, 2025

Septerna, Inc.(NasdaqGM: SEPN) added to S&P Pharmaceuticals Select Industry Index - marketscreener.com

Dec 21, 2025
pulisher
Dec 21, 2025

Septerna, Inc.(NasdaqGM: SEPN) added to NASDAQ Biotechnology Index - marketscreener.com

Dec 21, 2025
pulisher
Dec 21, 2025

Septerna’s SEP-631 Study: A Potential Game-Changer in Pharmaceutical Research - MSN

Dec 21, 2025

Septerna Inc Stock (SEPN) Financials Data

There is no financial data for Septerna Inc (SEPN). Check out other stocks for more information.

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading
$44.80
price up icon 1.24%
$26.75
price down icon 0.19%
$100.75
price up icon 1.93%
$105.76
price down icon 3.31%
$146.17
price down icon 1.52%
biotechnology ONC
$346.42
price down icon 1.38%
Cap:     |  Volume (24h):