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25.93
7.46%
1.80
Septerna Inc stock is traded at $25.93, with a volume of 815.96K.
It is up +7.46% in the last 24 hours and up +3.14% over the past month.
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
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Previous Close:
$24.13
Open:
$24.13
24h Volume:
815.96K
Relative Volume:
2.68
Market Cap:
$1.16B
Revenue:
$45.95M
Net Income/Loss:
$-48.88M
P/E Ratio:
-23.30
EPS:
-1.1129
Net Cash Flow:
$109.67M
1W Performance:
+5.88%
1M Performance:
+3.14%
6M Performance:
+11.14%
1Y Performance:
+312.24%
1-Day Range:
$23.31
$25.99
1-Week Range:
$22.83
$25.99
52-Week Range:
$5.73
$32.63
Septerna Inc Stock (SEPN) Company Profile
Name
Septerna Inc
Sector
Industry
Phone
650-338-3533
Address
250 EAST GRAND AVENUE, SUITE 65, SOUTH SAN FRANCISCO
Compare SEPN vs VRTX, REGN, ARGX, ALNY, ONC
| Stocks | Price | Market Cap | Revenue | Net Income | Cash Flow | EPS |
|---|---|---|---|---|---|---|
SEPN
Septerna Inc
|
25.93 | 1.08B | 45.95M | -48.88M | 109.67M | -1.1129 |
VRTX
Vertex Pharmaceuticals Inc
|
441.70 | 113.01B | 12.07B | 3.95B | 3.19B | 15.33 |
REGN
Regeneron Pharmaceuticals Inc
|
753.93 | 79.87B | 14.34B | 4.50B | 3.77B | 41.56 |
ARGX
Argen X Se Adr
|
840.87 | 51.51B | 4.16B | 1.29B | 734.26M | 19.58 |
ALNY
Alnylam Pharmaceuticals Inc
|
333.39 | 45.29B | 3.71B | 313.75M | 465.38M | 2.2571 |
ONC
Beone Medicines Ltd Adr
|
319.94 | 34.41B | 5.36B | 287.73M | 924.18M | 2.5229 |
Septerna Inc Stock (SEPN) Upgrades & Downgrades
| Date | Action | Analyst | Rating Change |
|---|---|---|---|
| Dec-19-25 | Initiated | Raymond James | Strong Buy |
| Dec-15-25 | Initiated | Truist | Buy |
| Nov-14-25 | Upgrade | Wells Fargo | Equal Weight → Overweight |
| Jun-23-25 | Initiated | H.C. Wainwright | Buy |
| Feb-18-25 | Downgrade | Wells Fargo | Overweight → Equal Weight |
| Nov-19-24 | Initiated | Cantor Fitzgerald | Overweight |
| Nov-19-24 | Initiated | JP Morgan | Overweight |
| Nov-19-24 | Initiated | TD Cowen | Buy |
| Nov-19-24 | Initiated | Wells Fargo | Overweight |
View All
Septerna Inc Stock (SEPN) Latest News
Septerna (SEPN) price target increased by 34.39% to 46.41 - MSN
SEPN Reiterated by HC Wainwright & Co. -- Price Target Maintained at $40 - GuruFocus
Septerna: Advancing GPCR Pipeline and Strategic Partnerships Support Buy Rating and $40 Price Target - TipRanks
Is Septerna (SEPN) Using Its First PTH1R Trial To Redefine Its GPCR Strategy? - Sahm
H.C. Wainwright reiterates Septerna stock rating on trial start By Investing.com - Investing.com South Africa
Septerna Announces Initiation of Phase 1 Clinical Trial of SEP-479, an Oral Small Molecule PTH1R Agonist for the Treatment of Hypoparathyroidism - Bitget
SEPTERNA INCPHASE 1 TRIAL DATA EXPECTED IN LATE 2026 OR EARLY 2027 - Moomoo
Septerna doses first patient in SEP-479 hypoparathyroidism trial By Investing.com - Investing.com Australia
Insider Buy: Is Septerna Inc part of any ETF2026 Sector Review & Risk Controlled Stock Alerts - baoquankhu1.vn
Septerna (SEPN) Initiates Phase 1 Trial for Hypoparathyroidism T - GuruFocus
Movement Recap: Will Septerna Inc benefit from current market trendsWeekly Loss Report & Accurate Buy Signal Notifications - baoquankhu1.vn
Septerna Begins Phase 1 Clinical Trial of SEP-479, an Oral PTH1R Agonist, for Hypoparathyroidism Treatment – Data Expected Late 2026/Early 2027 1 - Minichart
Septerna Begins Phase 1 Trial of Oral SEP-479 - TipRanks
Septerna doses first patient in SEP-479 hypoparathyroidism trial - Investing.com
Septerna begins Phase 1 trial of oral PTH1R agonist SEP-479; Phase 1 data expected late 2026–early 2027 - TradingView — Track All Markets
Septerna (Nasdaq: SEPN) begins Phase 1 trial of SEP-479 for hypoparathyroidism - Stock Titan
Septerna starts human testing of an oral drug for a lifelong disorder - Stock Titan
Buyout Rumor: How does Septerna Inc correlate with NasdaqEarnings Beat & Real-Time Volume Analysis - baoquankhu1.vn
FOMO Trade: Is Septerna Inc part of any ETF2026 Technical Overview & High Accuracy Trade Signal Alerts - baoquankhu1.vn
Will Septerna Inc benefit from current market trends2026 Price Momentum & Weekly High Conviction Ideas - baoquankhu1.vn
SEPN: Septerna, Inc.Detailed Earnings Estimates - Zacks Investment Research
Septerna tops Q4 loss expectations as collaboration revenue lifts results - MSN
Septerna, Inc. (NASDAQ:SEPN) Receives Average Recommendation of "Moderate Buy" from Analysts - MarketBeat
J.P. Morgan Maintains Septerna(SEPN.US) With Buy Rating, Announces Target Price $38 - Moomoo
Septerna (NASDAQ:SEPN) Given New $38.00 Price Target at JPMorgan Chase & Co. - marketbeat.com
JP Morgan Raises Price Target for Septerna (SEPN) to $38 | SEPN Stock News - GuruFocus
Septerna price target raised to $38 from $34 at JPMorgan - TipRanks
Should Septerna’s New ATM and Shelf Offering Strategy Require Action From Septerna (SEPN) Investors? - simplywall.st
Big Picture: How volatile is Septerna Inc stock2026 WrapUp & Free Low Drawdown Momentum Trade Ideas - baoquankhu1.vn
Septerna (SEPN) Expected to Announce Earnings on Thursday - MarketBeat
Layoff Watch: Will Septerna Inc outperform the market in YEARTrade Entry Report & Long-Term Safe Investment Ideas - baoquankhu1.vn
Septerna (SEPN) Is Down 13.5% After Launching US$150 Million ATM Equity Program and Filing Shelves - simplywall.st
Checkpoint Capital L.P. Trims Stock Position in Septerna, Inc. $SEPN - MarketBeat
Avoro Capital Advisors LLC Grows Stock Holdings in Septerna, Inc. $SEPN - MarketBeat
Septerna (NASDAQ:SEPN) Rating Lowered to "Hold" at Wall Street Zen - MarketBeat
HC Wainwright Has Negative Outlook for Septerna Q1 Earnings - MarketBeat
What is HC Wainwright's Forecast for Septerna Q1 Earnings? - MarketBeat
Analysts Conflicted on These Technology Names: Fortinet (FTNT), Septerna, Inc. (SEPN) and Oracle (ORCL) - The Globe and Mail
Truist Financial Forecasts Strong Price Appreciation for Septerna (NASDAQ:SEPN) Stock - MarketBeat
Septerna (SEPN) Q4 Loss Despite Revenue Surge Reinforces Bearish Profitability Narrative - simplywall.st
Wells Fargo Reaffirms Their Buy Rating on Septerna, Inc. (SEPN) - The Globe and Mail
Truist Lifts Price Target on Septerna to $35 From $34, Keeps Buy Rating - marketscreener.com
Cantor Fitzgerald Maintains Overweight on Septerna, Inc. (SEPN) March 2026 - Meyka
Truist raises Septerna stock price target to $35 on trial progress - Investing.com
Cantor Fitzgerald reiterates Septerna stock rating on platform value By Investing.com - Investing.com Australia
Cantor Fitzgerald reiterates Septerna stock rating on platform value - Investing.com
Septerna Inc Stock (SEPN) Financials Data
Revenue
Net Income
Cash Flow
EPS
2.69%
0.25%
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