114.17
price up icon3.41%   3.76
after-market After Hours: 114.17
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Rhythm Pharmaceuticals Inc stock is traded at $114.17, with a volume of 960.03K. It is up +3.41% in the last 24 hours and up +35.35% over the past month. Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
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Previous Close:
$110.41
Open:
$110.79
24h Volume:
960.03K
Relative Volume:
1.17
Market Cap:
$7.83B
Revenue:
$217.17M
Net Income/Loss:
$-202.68M
P/E Ratio:
-49.58
EPS:
-2.3028
Net Cash Flow:
$-156.63M
1W Performance:
+5.46%
1M Performance:
+35.35%
6M Performance:
+8.72%
1Y Performance:
+70.61%
1-Day Range:
Value
$109.78
$114.25
1-Week Range:
Value
$105.52
$114.58
52-Week Range:
Value
$64.65
$122.20

Rhythm Pharmaceuticals Inc Stock (RYTM) Company Profile

Name
Name
Rhythm Pharmaceuticals Inc
Name
Phone
857-264-4280
Name
Address
222 BERKELEY STREET, BOSTON, MA
Name
Employee
414
Name
Twitter
@rhythmpharma
Name
Next Earnings Date
2026-08-04
Name
Latest SEC Filings
Name
RYTM's Discussions on Twitter

Compare RYTM vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
RYTM icon
RYTM
Rhythm Pharmaceuticals Inc
114.17 7.62B 217.17M -202.68M -156.63M -2.3028
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
528.04 126.07B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
654.27 65.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
939.68 57.70B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
312.78 40.19B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
189.24 39.82B 742.00K -1.37B -1.07B -7.0731

Rhythm Pharmaceuticals Inc Stock (RYTM) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-19-26 Initiated RBC Capital Mkts Outperform
Nov-25-25 Initiated Citigroup Buy
Nov-05-25 Downgrade Oppenheimer Outperform → Perform
Jul-10-25 Initiated Goldman Buy
Jul-07-25 Initiated Leerink Partners Outperform
Apr-07-25 Upgrade BofA Securities Neutral → Buy
Mar-05-25 Resumed Stifel Buy
Jan-02-25 Initiated Jefferies Buy
Dec-20-24 Initiated Oppenheimer Outperform
Oct-21-24 Initiated Guggenheim Buy
Sep-18-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated JMP Securities Mkt Outperform
May-08-24 Downgrade BofA Securities Buy → Neutral
Dec-19-23 Upgrade Morgan Stanley Equal-Weight → Overweight
Aug-01-23 Upgrade BofA Securities Neutral → Buy
Jan-18-23 Resumed Canaccord Genuity Buy
Aug-08-22 Upgrade Goldman Neutral → Buy
Aug-05-22 Upgrade BofA Securities Underperform → Neutral
Jun-17-22 Reiterated Needham Buy
Mar-02-22 Resumed Stifel Buy
Feb-17-22 Upgrade Ladenburg Thalmann Neutral → Buy
Dec-08-21 Initiated Wells Fargo Overweight
Nov-19-21 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-14-21 Resumed Goldman Neutral
Aug-04-21 Downgrade BofA Securities Neutral → Underperform
Aug-04-21 Downgrade Ladenburg Thalmann Buy → Neutral
Nov-30-20 Downgrade BofA Securities Buy → Neutral
Jan-08-20 Initiated Goldman Sell
Jul-12-19 Upgrade Stifel Hold → Buy
Jul-08-19 Initiated Canaccord Genuity Buy
Mar-13-19 Initiated Ladenburg Thalmann Buy
Sep-07-18 Resumed Morgan Stanley Overweight
Jun-25-18 Reiterated Needham Buy
Jun-15-18 Reiterated Needham Buy
Oct-30-17 Initiated BofA/Merrill Buy
Oct-30-17 Initiated Needham Buy
View All

Rhythm Pharmaceuticals Inc Stock (RYTM) Latest News

pulisher
Jun 30, 2026

Rhythm Pharmaceuticals stock trades up to $111.03 as Rhythm Pharmaceuticals closes offices for July 4th break - Traders Union

Jun 30, 2026
pulisher
Jun 30, 2026

Rhythm Pharmaceuticals Stock Surges 28%, With A 12-Day Winning Spree - Trefis

Jun 30, 2026
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Jun 30, 2026

Is Rhythm Pharmaceuticals, Inc. (RYTM) Stock Poised for Growth After Encouraging Setmelanotide Trial Results? - Insider Monkey

Jun 30, 2026
pulisher
Jun 30, 2026

Rhythm Pharmaceuticals Stock On Fire: Up 28% With 12-Day Winning Streak - Trefis

Jun 30, 2026
pulisher
Jun 29, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: A Biotech with Promising Upside and Strong Buy Ratings - DirectorsTalk Interviews

Jun 29, 2026
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Jun 28, 2026

(RYTM) Price Dynamics and Execution-Aware Positioning - Stock Traders Daily

Jun 28, 2026
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Jun 26, 2026

Rhythm Pharmaceuticals highlights obesity pipeline, shares track sector peers - Ad-hoc-news.de

Jun 26, 2026
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Jun 26, 2026

Rhythm Pharmaceuticals Stock On Fire: Up 26% With 10-Day Winning Streak - Trefis

Jun 26, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals 8-K Filing June 2026 – Company Details, Nasdaq Listing, and Executive Information - Minichart

Jun 25, 2026
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Jun 25, 2026

Form 4 Rhythm Pharmaceuticals Inc For: 25 June By Investing.com - Investing.com South Africa

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals | 4: Statement of changes in beneficial ownership of securities-Director JEAN CHRISTOPHE - Moomoo

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals (RYTM) director receives RSUs, options and converts 4,712 RSUs - Stock Titan

Jun 25, 2026
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Jun 25, 2026

[Form 4] RHYTHM PHARMACEUTICALS, INC. Insider Trading Activity - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals | 4: Statement of changes in beneficial ownership of securities-Director MCGIRR DAVID W J - Moomoo

Jun 25, 2026
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Jun 25, 2026

Director at Rhythm Pharmaceuticals (RYTM) receives new RSUs, options and exercises units - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals (RYTM) director granted RSUs, stock options and converts RSUs to shares - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals | 4: Statement of changes in beneficial ownership of securities-Director Arbuckle Stuart A - Moomoo

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals (RYTM) director granted RSUs, options and new shares - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals (NASDAQ: RYTM) holders approve directors, pay and Ernst & Young - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals | 8-K: Current report - Moomoo

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals, Inc. Actuals & Estimates (NASDAQ:RYTM) - TradingView

Jun 25, 2026
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Jun 25, 2026

RYTM Forecast — Price Target — Prediction for 2027 - TradingView

Jun 25, 2026
pulisher
Jun 25, 2026

Rhythm Pharmaceuticals (RYTM) Is Up 7.9% After Promising Early PWS Data for SetmelanotideWhat's Changed - Sahm

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals Inc (RYTM) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jun 25, 2026
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Jun 24, 2026

Rhythm Pharmaceuticals(RYTM.US) Director Sells US$3.71 Million in Common Stock - Moomoo

Jun 24, 2026
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Jun 24, 2026

Rhythm Pharmaceuticals (RYTM) director exercises options and sells 37,000 shares - Stock Titan

Jun 24, 2026
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Jun 24, 2026

Rhythm Pharmaceuticals | 4: Statement of changes in beneficial ownership of securities-Director TETRAULT LYNN A. - Moomoo

Jun 24, 2026
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Jun 24, 2026

8-Day Rally Sends Rhythm Pharmaceuticals Stock Up 24% - Trefis

Jun 24, 2026
pulisher
Jun 23, 2026

Rhythm Pharmaceuticals (RYTM) Stock Could Be 30.6% Undervalued on Its Growth Narrative - Sahm

Jun 23, 2026
pulisher
Jun 22, 2026

Form 144 RHYTHM PHARMACEUTICALS For: 22 June By Investing.com - Investing.com Nigeria

Jun 22, 2026
pulisher
Jun 22, 2026

Rhythm Pharmaceuticals stock surges 4.98% as RhythmPharma announces Dr. Shoemaker joins as Senior Medical Director - Traders Union

Jun 22, 2026
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Jun 22, 2026

Form 144 | Rhythm Pharmaceuticals(RYTM.US) Director Proposes to Sell 3.58 Million in Common Stocks - Moomoo

Jun 22, 2026
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Jun 22, 2026

Rhythm Pharmaceuticals | 144: Notice of proposed sale of securities pursuant to Rule 144 - Moomoo

Jun 22, 2026
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Jun 22, 2026

[144] RHYTHM PHARMACEUTICALS, INC. SEC Filing - Stock Titan

Jun 22, 2026
pulisher
Jun 22, 2026

Can Rhythm Pharmaceuticals (RYTM) ’s New Data Help Patients With a Rare Hunger Disorder? - Insider Monkey

Jun 22, 2026
pulisher
Jun 21, 2026

A Quick Look at Today's Ratings for Rhythm Pharmaceuticals(RYTM.US), With a Forecast Between $105 to $155 - Moomoo

Jun 21, 2026
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Jun 21, 2026

CCORF Maintains Rhythm Pharmaceuticals(RYTM.US) With Buy Rating, Raises Target Price to $151 - Moomoo

Jun 21, 2026
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Jun 19, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) reports Q1 loss, tops revenue estimates - MSN

Jun 19, 2026
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Jun 19, 2026

Rhythm Pharmaceuticals Inc (RYTM) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

Jun 19, 2026
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Jun 19, 2026

Rhythm Pharmaceuticals Inc (RYTM) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jun 19, 2026
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Jun 18, 2026

Rhythm Pharmaceuticals Inc - TradingKey

Jun 18, 2026
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Jun 17, 2026

Rhythm Pharmaceuticals stock price target reiterated at $130 by TD Cowen By Investing.com - Investing.com South Africa

Jun 17, 2026
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Jun 17, 2026

RYTM Stock Climbs As PWS Data Drive Analyst Upgrades - StocksToTrade

Jun 17, 2026
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Jun 17, 2026

Palatin Technologies Is Pursuing the Next Generation of MC4R. Rhythm Just Reinforced Why That Matters - Benzinga

Jun 17, 2026
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Jun 17, 2026

Rhythm Pharmaceuticals Inc (RYTM) Institutional Confidence - TradingKey

Jun 17, 2026
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Jun 17, 2026

(RYTM) as a Liquidity Pulse for Institutional Tactics - Stock Traders Daily

Jun 17, 2026
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Jun 17, 2026

Rhythm Pharmaceuticals Inc (RYTM) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Discusses Positive Interim Results from Phase 2 Setmelanotide Trial in Prader-Willi SyndromeSlideshow (NASDAQ:RYTM) 2026-06-17 - Seeking Alpha

Jun 17, 2026
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Jun 17, 2026

RYTM News | RHYTHM PHARMACEUTICALS INC (NASDAQ:RYTM) - ChartMill

Jun 17, 2026
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Jun 17, 2026

Rhythm Pharmaceuticals Inc (RYTM) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jun 17, 2026
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Jun 17, 2026

Rhythm Pharmaceuticals Inc (RYTM) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jun 17, 2026

Rhythm Pharmaceuticals Inc Stock (RYTM) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Rhythm Pharmaceuticals Inc Stock (RYTM) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
TETRAULT LYNN A.
Director
Jun 22 '26
Sale
100.32
37,000
3,711,896
7,000
$97.55
price up icon 3.86%
$35.13
price up icon 0.29%
$57.77
price up icon 3.57%
ONC ONC
$297.65
price up icon 2.38%
$79.76
price up icon 10.01%
$189.24
price up icon 0.92%
Cap:     |  Volume (24h):