106.60
price up icon0.48%   0.51
after-market After Hours: 108.46 1.86 +1.74%
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Rhythm Pharmaceuticals Inc stock is traded at $106.60, with a volume of 773.29K. It is up +0.48% in the last 24 hours and up +11.24% over the past month. Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
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Previous Close:
$106.09
Open:
$104.92
24h Volume:
773.29K
Relative Volume:
0.99
Market Cap:
$7.31B
Revenue:
$217.17M
Net Income/Loss:
$-202.68M
P/E Ratio:
-46.29
EPS:
-2.3028
Net Cash Flow:
$-156.63M
1W Performance:
-1.66%
1M Performance:
+11.24%
6M Performance:
+4.89%
1Y Performance:
+17.56%
1-Day Range:
Value
$104.20
$108.40
1-Week Range:
Value
$104.20
$110.69
52-Week Range:
Value
$74.50
$122.20

Rhythm Pharmaceuticals Inc Stock (RYTM) Company Profile

Name
Name
Rhythm Pharmaceuticals Inc
Name
Phone
857-264-4280
Name
Address
222 BERKELEY STREET, BOSTON, MA
Name
Employee
414
Name
Twitter
@rhythmpharma
Name
Next Earnings Date
2026-08-04
Name
Latest SEC Filings
Name
RYTM's Discussions on Twitter

Compare RYTM vs VRTX, REGN, ARGX, RVMD, ALNY

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
RYTM icon
RYTM
Rhythm Pharmaceuticals Inc
106.60 7.28B 217.17M -202.68M -156.63M -2.3028
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
485.65 123.36B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
676.69 71.18B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
860.55 53.68B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
186.16 38.09B 742.00K -1.37B -1.07B -7.0731
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
267.47 37.80B 4.29B 577.22M 641.34M 4.2086

Rhythm Pharmaceuticals Inc Stock (RYTM) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-19-26 Initiated RBC Capital Mkts Outperform
Nov-25-25 Initiated Citigroup Buy
Nov-05-25 Downgrade Oppenheimer Outperform → Perform
Jul-10-25 Initiated Goldman Buy
Jul-07-25 Initiated Leerink Partners Outperform
Apr-07-25 Upgrade BofA Securities Neutral → Buy
Mar-05-25 Resumed Stifel Buy
Jan-02-25 Initiated Jefferies Buy
Dec-20-24 Initiated Oppenheimer Outperform
Oct-21-24 Initiated Guggenheim Buy
Sep-18-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated JMP Securities Mkt Outperform
May-08-24 Downgrade BofA Securities Buy → Neutral
Dec-19-23 Upgrade Morgan Stanley Equal-Weight → Overweight
Aug-01-23 Upgrade BofA Securities Neutral → Buy
Jan-18-23 Resumed Canaccord Genuity Buy
Aug-08-22 Upgrade Goldman Neutral → Buy
Aug-05-22 Upgrade BofA Securities Underperform → Neutral
Jun-17-22 Reiterated Needham Buy
Mar-02-22 Resumed Stifel Buy
Feb-17-22 Upgrade Ladenburg Thalmann Neutral → Buy
Dec-08-21 Initiated Wells Fargo Overweight
Nov-19-21 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-14-21 Resumed Goldman Neutral
Aug-04-21 Downgrade BofA Securities Neutral → Underperform
Aug-04-21 Downgrade Ladenburg Thalmann Buy → Neutral
Nov-30-20 Downgrade BofA Securities Buy → Neutral
Jan-08-20 Initiated Goldman Sell
Jul-12-19 Upgrade Stifel Hold → Buy
Jul-08-19 Initiated Canaccord Genuity Buy
Mar-13-19 Initiated Ladenburg Thalmann Buy
Sep-07-18 Resumed Morgan Stanley Overweight
Jun-25-18 Reiterated Needham Buy
Jun-15-18 Reiterated Needham Buy
Oct-30-17 Initiated BofA/Merrill Buy
Oct-30-17 Initiated Needham Buy
View All

Rhythm Pharmaceuticals Inc Stock (RYTM) Latest News

pulisher
Jul 16, 2026

Law firm probes Rhythm Pharmaceuticals officers for possible self-dealing harming shareholders - Pluang

Jul 16, 2026
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Jul 16, 2026

Kuehn Law Encourages Investors of Rhythm Pharmaceuticals, Inc. to Contact Law Firm - GlobeNewswire Inc.

Jul 16, 2026
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Jul 15, 2026

symbol__ Stock Quote Price and Forecast - CNN

Jul 15, 2026
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Jul 14, 2026

Enterprise value to revenue forward of Rhythm Pharmaceuticals, Inc. – BMV:RYTM - TradingView

Jul 14, 2026
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Jul 14, 2026

Does NEJM-Validated TRANSCEND Data on Setmelanotide Reshape the Bull Case for Rhythm Pharmaceuticals (RYTM)? - Sahm

Jul 14, 2026
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Jul 14, 2026

Rhythm Pharmaceuticals (RYTM) Edges Higher, Nears Key Resistance LevelSymmetrical Triangle - dars.gov.et

Jul 14, 2026
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Jul 14, 2026

Citizens reiterates Rhythm Pharmaceuticals stock rating on strong Imcivree launch data - Investing.com Canada

Jul 14, 2026
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Jul 13, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: Exploring a 28.91% Upside Potential in Biotechnology - DirectorsTalk Interviews

Jul 13, 2026
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Jul 12, 2026

Enterprise value to EBITDA forward of Rhythm Pharmaceuticals, Inc. – NASDAQ:RYTM - TradingView

Jul 12, 2026
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Jul 12, 2026

Price to earnings forward of Rhythm Pharmaceuticals, Inc. – NASDAQ:RYTM - TradingView

Jul 12, 2026
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Jul 09, 2026

Price-Driven Insight from (RYTM) for Rule-Based Strategy - Stock Traders Daily

Jul 09, 2026
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Jul 09, 2026

Enterprise value to revenue forward of Rhythm Pharmaceuticals, Inc. – XETR:1RV - TradingView

Jul 09, 2026
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Jul 09, 2026

Rhythm Pharmaceuticals (RYTM) On TRANSCEND And New Approvals, Buying Opportunity Or Priced In? - Sahm

Jul 09, 2026
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Jul 08, 2026

Rhythm Pharmaceuticals Inc. announced that the results of its Phase 3 Transcend clinical trial for acquired hypothalamic obesity have been published in the top international medical journal, The New England Journal of Medicine. - Bitget

Jul 08, 2026
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Jul 08, 2026

Rhythm Pharmaceuticals Announces NEJM Publication of Phase 3 TRANSCEND Trial Results for Setmelanotide in Acquired Hypothalamic Obesity - Quiver Quantitative

Jul 08, 2026
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Jul 08, 2026

Rhythm Pharmaceuticals Announces The New England Journal of - GlobeNewswire

Jul 08, 2026
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Jul 08, 2026

Rhythm Pharmaceuticals Announces The New England Journal of Medicine Publication of Phase 3 TRANSCEND Trial Results in Acquired Hypothalamic Obesity - Yahoo Finance UK

Jul 08, 2026
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Jul 08, 2026

CCORF Maintains Rhythm Pharmaceuticals(RYTM.US) With Buy Rating, Maintains Target Price $151 - Moomoo

Jul 08, 2026
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Jul 07, 2026

RYTM Maintained by RBC Capital -- Price Target Raised to $141.00 - GuruFocus

Jul 07, 2026
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Jul 07, 2026

Rhythm Pharmaceuticals balances obesity-drug growth prospects and biotech risks - Ad-hoc-news.de

Jul 07, 2026
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Jul 07, 2026

RBC Capital Adjusts Rhythm Pharmaceuticals Price Target to $141 From $137, Maintains Outperform Rating - marketscreener.com

Jul 07, 2026
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Jul 06, 2026

Rhythm Pharmaceuticals Announces New Data Presentations In Acquired Hypothalamic Obesity At Pediatric Endocrine Society >RYTM - Moomoo

Jul 06, 2026
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Jul 06, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: A Biotech Contender with 22% Upside Potential - DirectorsTalk Interviews

Jul 06, 2026
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Jul 05, 2026

Price to sales forward of Rhythm Pharmaceuticals, Inc. – NASDAQ:RYTM - TradingView

Jul 05, 2026
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Jul 04, 2026

RYTMRhythm Pharmaceuticals Inc Options - Finviz

Jul 04, 2026
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Jul 03, 2026

Rhythm Pharmaceuticals announces public offering of common stock - MSN

Jul 03, 2026
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Jul 03, 2026

Rhythm Pharmaceuticals Inc to Discuss Interim Six-Month Phase 2 Results Evaluating Setmelanotide Call Transcript - GuruFocus

Jul 03, 2026
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Jul 02, 2026

Rhythm Pharmaceuticals (RYTM) CSO exercises RSUs, 2,150 shares withheld for taxes - Stock Titan

Jul 02, 2026
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Jun 30, 2026

Rhythm Pharmaceuticals Stock On Fire: Up 28% With 12-Day Winning Streak - Trefis

Jun 30, 2026
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Jun 30, 2026

Rhythm Pharmaceuticals stock trades up to $111.03 as Rhythm Pharmaceuticals closes offices for July 4th break - Traders Union

Jun 30, 2026
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Jun 30, 2026

Rhythm Pharmaceuticals Stock Surges 28%, With A 12-Day Winning Spree - Trefis

Jun 30, 2026
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Jun 30, 2026

Is Rhythm Pharmaceuticals, Inc. (RYTM) Stock Poised for Growth After Encouraging Setmelanotide Trial Results? - Insider Monkey

Jun 30, 2026
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Jun 29, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: A Biotech with Promising Upside and Strong Buy Ratings - DirectorsTalk Interviews

Jun 29, 2026
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Jun 29, 2026

Rhythm Pharmaceuticals Stock Rockets 28% With 11-Day Winning Streak - Trefis

Jun 29, 2026
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Jun 28, 2026

(RYTM) Price Dynamics and Execution-Aware Positioning - Stock Traders Daily

Jun 28, 2026
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Jun 26, 2026

Rhythm Pharmaceuticals highlights obesity pipeline, shares track sector peers - Ad-hoc-news.de

Jun 26, 2026
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Jun 26, 2026

Rhythm Pharmaceuticals Stock On Fire: Up 26% With 10-Day Winning Streak - Trefis

Jun 26, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals 8-K Filing June 2026 – Company Details, Nasdaq Listing, and Executive Information - Minichart

Jun 25, 2026
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Jun 25, 2026

Form 4 Rhythm Pharmaceuticals Inc For: 25 June By Investing.com - Investing.com South Africa

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals | 4: Statement of changes in beneficial ownership of securities-Director JEAN CHRISTOPHE - Moomoo

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals (RYTM) director receives RSUs, options and converts 4,712 RSUs - Stock Titan

Jun 25, 2026
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Jun 25, 2026

[Form 4] RHYTHM PHARMACEUTICALS, INC. Insider Trading Activity - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals | 4: Statement of changes in beneficial ownership of securities-Director MCGIRR DAVID W J - Moomoo

Jun 25, 2026
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Jun 25, 2026

Director at Rhythm Pharmaceuticals (RYTM) receives new RSUs, options and exercises units - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals (RYTM) director granted RSUs, stock options and converts RSUs to shares - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals | 4: Statement of changes in beneficial ownership of securities-Director Arbuckle Stuart A - Moomoo

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals (RYTM) director granted RSUs, options and new shares - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals | 4: Statement of changes in beneficial ownership of securities-Director GOOD JENNIFER L - Moomoo

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals (NASDAQ: RYTM) holders approve directors, pay and Ernst & Young - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals | 8-K: Current report - Moomoo

Jun 25, 2026
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Jun 25, 2026

Rhythm Pharmaceuticals, Inc. Actuals & Estimates (NASDAQ:RYTM) - TradingView

Jun 25, 2026

Rhythm Pharmaceuticals Inc Stock (RYTM) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Rhythm Pharmaceuticals Inc Stock (RYTM) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
TETRAULT LYNN A.
Director
Jun 22 '26
Sale
100.32
37,000
3,711,896
7,000
$108.32
price up icon 0.80%
$61.82
price down icon 2.11%
$34.51
price up icon 1.71%
$58.18
price down icon 0.60%
ONC ONC
$312.02
price down icon 1.70%
$267.47
price down icon 5.54%
Cap:     |  Volume (24h):