84.62
price up icon2.46%   2.03
after-market After Hours: 72.10 -12.52 -14.80%
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Rhythm Pharmaceuticals Inc stock is traded at $84.62, with a volume of 1.15M. It is up +2.46% in the last 24 hours and down -14.65% over the past month. Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
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Previous Close:
$82.59
Open:
$82.6
24h Volume:
1.15M
Relative Volume:
1.47
Market Cap:
$5.78B
Revenue:
$189.76M
Net Income/Loss:
$-196.54M
P/E Ratio:
-27.22
EPS:
-3.1087
Net Cash Flow:
$-156.63M
1W Performance:
-1.44%
1M Performance:
-14.65%
6M Performance:
-14.65%
1Y Performance:
+59.93%
1-Day Range:
Value
$80.99
$84.85
1-Week Range:
Value
$80.70
$100.00
52-Week Range:
Value
$45.91
$122.20

Rhythm Pharmaceuticals Inc Stock (RYTM) Company Profile

Name
Name
Rhythm Pharmaceuticals Inc
Name
Phone
857-264-4280
Name
Address
222 BERKELEY STREET, BOSTON, MA
Name
Employee
414
Name
Twitter
@rhythmpharma
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
RYTM's Discussions on Twitter

Compare RYTM vs VRTX, REGN, ALNY, ARGX, INSM

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
RYTM icon
RYTM
Rhythm Pharmaceuticals Inc
84.62 5.64B 189.76M -196.54M -156.63M -3.1087
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
454.97 113.96B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
749.47 78.41B 14.34B 4.50B 3.77B 41.56
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
328.70 40.85B 3.71B 313.75M 465.38M 2.2571
ARGX icon
ARGX
Argen X Se Adr
697.05 42.05B 4.16B 1.29B 734.26M 19.58
INSM icon
INSM
Insmed Inc
148.31 29.99B 606.42M -1.28B -997.58M -6.403

Rhythm Pharmaceuticals Inc Stock (RYTM) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-19-26 Initiated RBC Capital Mkts Outperform
Nov-25-25 Initiated Citigroup Buy
Nov-05-25 Downgrade Oppenheimer Outperform → Perform
Jul-10-25 Initiated Goldman Buy
Jul-07-25 Initiated Leerink Partners Outperform
Apr-07-25 Upgrade BofA Securities Neutral → Buy
Mar-05-25 Resumed Stifel Buy
Jan-02-25 Initiated Jefferies Buy
Dec-20-24 Initiated Oppenheimer Outperform
Oct-21-24 Initiated Guggenheim Buy
Sep-18-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated JMP Securities Mkt Outperform
May-08-24 Downgrade BofA Securities Buy → Neutral
Dec-19-23 Upgrade Morgan Stanley Equal-Weight → Overweight
Aug-01-23 Upgrade BofA Securities Neutral → Buy
Jan-18-23 Resumed Canaccord Genuity Buy
Aug-08-22 Upgrade Goldman Neutral → Buy
Aug-05-22 Upgrade BofA Securities Underperform → Neutral
Jun-17-22 Reiterated Needham Buy
Mar-02-22 Resumed Stifel Buy
Feb-17-22 Upgrade Ladenburg Thalmann Neutral → Buy
Dec-08-21 Initiated Wells Fargo Overweight
Nov-19-21 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-14-21 Resumed Goldman Neutral
Aug-04-21 Downgrade BofA Securities Neutral → Underperform
Aug-04-21 Downgrade Ladenburg Thalmann Buy → Neutral
Nov-30-20 Downgrade BofA Securities Buy → Neutral
Jan-08-20 Initiated Goldman Sell
Jul-12-19 Upgrade Stifel Hold → Buy
Jul-08-19 Initiated Canaccord Genuity Buy
Mar-13-19 Initiated Ladenburg Thalmann Buy
Sep-07-18 Resumed Morgan Stanley Overweight
Jun-25-18 Reiterated Needham Buy
Jun-15-18 Reiterated Needham Buy
Oct-30-17 Initiated BofA/Merrill Buy
Oct-30-17 Initiated Needham Buy
View All

Rhythm Pharmaceuticals Inc Stock (RYTM) Latest News

pulisher
Mar 24, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Discusses FDA Approval of IMCIVREE for Acquired Hypothalamic ObesitySlideshow (NASDAQ:RYTM) 2026-03-24 - Seeking Alpha

Mar 24, 2026
pulisher
Mar 23, 2026

RYTM: HC Wainwright & Co. Maintains 'Buy' Rating, Raises Price T - GuruFocus

Mar 23, 2026
pulisher
Mar 23, 2026

H.C. Wainwright raises Rhythm Pharmaceuticals stock price target on FDA approval - Investing.com Canada

Mar 23, 2026
pulisher
Mar 23, 2026

Levels Update: What hedge funds are buying Rhythm Pharmaceuticals IncMarket Rally & Accurate Entry/Exit Alerts - baoquankhu1.vn

Mar 23, 2026
pulisher
Mar 23, 2026

Rhythm wins US nod for Imcivree in rare hypothalamic obesity - The Pharma Letter

Mar 23, 2026
pulisher
Mar 23, 2026

PANTHERx® Rare Selected by Rhythm Pharmaceuticals Inc. as the Exclusive U.S. Specialty Pharmacy for the Expanded Indication for IMCIVREE® (setmelanotide) - BioSpace

Mar 23, 2026
pulisher
Mar 22, 2026

Tech Rally: Is Rhythm Pharmaceuticals Inc. gaining market share2026 PreEarnings & Technical Pattern Based Signals - baoquankhu1.vn

Mar 22, 2026
pulisher
Mar 22, 2026

Rhythm Pharmaceuticals (RYTM) reports phase 3 EMANATE trial topline results for setmelanotide - MSN

Mar 22, 2026
pulisher
Mar 22, 2026

Rhythm Pharmaceuticals Announces FDA Approval of IMCIVREE® (setme - The National Law Review

Mar 22, 2026
pulisher
Mar 22, 2026

How Investors May Respond To Rhythm Pharmaceuticals (RYTM) FDA Win For IMCIVREE In Acquired Hypothalamic Obesity - Yahoo Finance

Mar 22, 2026
pulisher
Mar 22, 2026

Rhythm Pharmaceuticals Wins FDA Approval for IMCIVREE in Acquired Hypothalamic Obesity Launch - Yahoo Finance

Mar 22, 2026
pulisher
Mar 22, 2026

Rhythm Pharmaceuticals EMANATE Phase 3 Misses Primary Endpoint, Sees Subgroup Signals for Setmelanotide - MarketBeat

Mar 22, 2026
pulisher
Mar 20, 2026

Rhythm Grabs A New Obesity Approval; How It Edged In Where Lilly, Novo 'Have Fallen Flat' - Investor's Business Daily

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals (RYTM) Receives Buy Rating and Raised Pri - GuruFocus

Mar 20, 2026
pulisher
Mar 20, 2026

RYTM: Citigroup Raises Price Target on Rhythm Pharmaceuticals | - GuruFocus

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals (RYTM) Expands IMCIVREE Distribution Part - GuruFocus

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals (RYTM) Reports Phase 3 EMANATE Trial Topline Results for Setmelanotide - Insider Monkey

Mar 20, 2026
pulisher
Mar 20, 2026

RYTM Earning Date, Earning Analysis and Earning Prediction - Intellectia AI

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals (NASDAQ:RYTM) Shares Gap UpHere's What Happened - MarketBeat

Mar 20, 2026
pulisher
Mar 20, 2026

FDA Approves IMCIVREE (Setmelanotide) as First Therapy for Acquired Hypothalamic Obesity in Adults and Children 4+ - Minichart

Mar 20, 2026
pulisher
Mar 20, 2026

**Rhythm Pharmaceuticals Surges with Significant Market Moves After FDA Expansion** - StocksToTrade

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals jumps as investors focus on FDA decision timing for hypothalamic obesity label expansion - Quiver Quantitative

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals price target raised to $149 from $139 at BofA - TipRanks

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Wins FDA Nod for Hypothalamic Obesity Therapy - TipRanks

Mar 20, 2026
pulisher
Mar 20, 2026

Why Is Rhythm Pharma Stock Gaining Friday?Rhythm Pharmaceuticals (NASDAQ:RYTM) - Benzinga

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals wins FDA approval for IMCIVREE in acquired hypothalamic obesity; Phase 3 shows -18.4% placebo‑adjusted BMI - TradingView

Mar 20, 2026
pulisher
Mar 20, 2026

Palatin's Case Strengthens as Rhythm's FDA Approval Validates Hypothalamic Obesity Market (PTN) - Benzinga

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals (Nasdaq: RYTM) gains FDA OK for IMCIVREE in acquired hypothalamic obesity - Stock Titan

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm obesity drug wins broader use from FDA - BioPharma Dive

Mar 20, 2026
pulisher
Mar 20, 2026

HC Wainwright Analysts Lower Earnings Estimates for RYTM - MarketBeat

Mar 20, 2026
pulisher
Mar 20, 2026

After setback, Rhythm gets good news on Imcivree from FDA - pharmaphorum

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals (RYTM) Gains on FDA Approval for Expanded Use of Imcivree - GuruFocus

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals stock jumps on FDA approval - Investing.com

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals stock jumps on FDA approval By Investing.com - Investing.com Canada

Mar 20, 2026
pulisher
Mar 20, 2026

After receiving approval from the U.S. Food and Drug Administration (FDA) for its brain injury-related obesity treatment, Rhythm Pharmaceuticals Inc. (RYTM) shares surged 7.4% in pre-market trading. - Bitget

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharma higher after FDA label expansion for lead drug - Seeking Alpha

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm's therapy becomes first FDA-approved treatment for brain damage-related obesity - Reuters

Mar 20, 2026
pulisher
Mar 20, 2026

Rhythm Pharmaceuticals’ Phase 3 EMANATE trial falls short of primary goals - Indian Pharma Post

Mar 20, 2026
pulisher
Mar 20, 2026

Is First FDA‑Approved IMCIVREE Use In Hypothalamic Obesity Altering The Investment Case For Rhythm Pharmaceuticals (RYTM)? - Sahm

Mar 20, 2026
pulisher
Mar 19, 2026

5 Most Promising Stocks Under $100 to Buy - Insider Monkey

Mar 19, 2026
pulisher
Mar 19, 2026

Rhythm Pharmaceuticals Announces FDA Approval of IMCIVREE® (setmelanotide) for Patients with Acquired Hypothalamic Obesity - The Manila Times

Mar 19, 2026
pulisher
Mar 19, 2026

Rhythm Awaits FDA Decision On Expanded Use Of Imcivree In Hypothalamic Obesity - RTTNews

Mar 19, 2026
pulisher
Mar 19, 2026

HC Wainwright Issues Negative Estimate for RYTM Earnings - MarketBeat

Mar 19, 2026
pulisher
Mar 18, 2026

Jefferies Maintains Buy Rating on Rhythm Pharmaceuticals (RYTM), Sets $80 Price Target - MSN

Mar 18, 2026
pulisher
Mar 18, 2026

Rhythm Pharmaceuticals (RYTM) PT Increased From $136 to $143 at Wells Fargo on IMCIVREE Launch Optimism - Insider Monkey

Mar 18, 2026
pulisher
Mar 18, 2026

H.C. Wainwright cuts Rhythm Pharmaceuticals stock price target on trial miss - Investing.com Canada

Mar 18, 2026
pulisher
Mar 18, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) expected to beat earnings estimates: Should you buy? - MSN

Mar 18, 2026
pulisher
Mar 18, 2026

HC Wainwright Issues Pessimistic Forecast for Rhythm Pharmaceuticals (NASDAQ:RYTM) Stock Price - MarketBeat

Mar 18, 2026
pulisher
Mar 18, 2026

Rhythm Pharmaceuticals: EMANATE Setback but Validated MC4R Mechanism and Pipeline Optionality Support Lowered $100 Buy Rating - TipRanks

Mar 18, 2026
pulisher
Mar 18, 2026

HC Wainwright & Co. Lowers Price Target for Rhythm Pharmaceutica - GuruFocus

Mar 18, 2026
pulisher
Mar 18, 2026

Analysts Offer Insights on Healthcare Companies: Rhythm Pharmaceuticals (RYTM) and Merck & Company (MRK) - The Globe and Mail

Mar 18, 2026

Rhythm Pharmaceuticals Inc Stock (RYTM) Financials Data

Revenue

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Net Income

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Rhythm Pharmaceuticals Inc Stock (RYTM) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
German Christopher Paul
Corporate Controller & CAO
Mar 04 '26
Sale
89.56
5,614
502,790
160
$27.36
price up icon 1.82%
$47.03
price up icon 3.20%
$53.54
price up icon 4.29%
$88.77
price up icon 2.26%
ONC ONC
$283.45
price up icon 2.81%
$148.31
price up icon 6.59%
Cap:     |  Volume (24h):