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Rhythm Pharmaceuticals Inc stock is traded at $96.79, with a volume of 1.56M. It is up +1.00% in the last 24 hours and up +11.46% over the past month. Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
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Previous Close:
$95.83
Open:
$97.56
24h Volume:
1.56M
Relative Volume:
1.89
Market Cap:
$6.64B
Revenue:
$217.17M
Net Income/Loss:
$-202.68M
P/E Ratio:
-42.03
EPS:
-2.3028
Net Cash Flow:
$-156.63M
1W Performance:
+10.42%
1M Performance:
+11.46%
6M Performance:
-13.37%
1Y Performance:
+57.43%
1-Day Range:
Value
$95.97
$99.95
1-Week Range:
Value
$87.65
$99.95
52-Week Range:
Value
$60.80
$122.20

Rhythm Pharmaceuticals Inc Stock (RYTM) Company Profile

Name
Name
Rhythm Pharmaceuticals Inc
Name
Phone
857-264-4280
Name
Address
222 BERKELEY STREET, BOSTON, MA
Name
Employee
414
Name
Twitter
@rhythmpharma
Name
Next Earnings Date
2026-08-04
Name
Latest SEC Filings
Name
RYTM's Discussions on Twitter

Compare RYTM vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
RYTM icon
RYTM
Rhythm Pharmaceuticals Inc
96.79 6.64B 217.17M -202.68M -156.63M -2.3028
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
451.63 114.63B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
609.94 63.95B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
877.72 54.58B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
278.09 37.13B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
162.99 34.65B 742.00K -1.37B -1.07B -7.0731

Rhythm Pharmaceuticals Inc Stock (RYTM) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-19-26 Initiated RBC Capital Mkts Outperform
Nov-25-25 Initiated Citigroup Buy
Nov-05-25 Downgrade Oppenheimer Outperform → Perform
Jul-10-25 Initiated Goldman Buy
Jul-07-25 Initiated Leerink Partners Outperform
Apr-07-25 Upgrade BofA Securities Neutral → Buy
Mar-05-25 Resumed Stifel Buy
Jan-02-25 Initiated Jefferies Buy
Dec-20-24 Initiated Oppenheimer Outperform
Oct-21-24 Initiated Guggenheim Buy
Sep-18-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated JMP Securities Mkt Outperform
May-08-24 Downgrade BofA Securities Buy → Neutral
Dec-19-23 Upgrade Morgan Stanley Equal-Weight → Overweight
Aug-01-23 Upgrade BofA Securities Neutral → Buy
Jan-18-23 Resumed Canaccord Genuity Buy
Aug-08-22 Upgrade Goldman Neutral → Buy
Aug-05-22 Upgrade BofA Securities Underperform → Neutral
Jun-17-22 Reiterated Needham Buy
Mar-02-22 Resumed Stifel Buy
Feb-17-22 Upgrade Ladenburg Thalmann Neutral → Buy
Dec-08-21 Initiated Wells Fargo Overweight
Nov-19-21 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-14-21 Resumed Goldman Neutral
Aug-04-21 Downgrade BofA Securities Neutral → Underperform
Aug-04-21 Downgrade Ladenburg Thalmann Buy → Neutral
Nov-30-20 Downgrade BofA Securities Buy → Neutral
Jan-08-20 Initiated Goldman Sell
Jul-12-19 Upgrade Stifel Hold → Buy
Jul-08-19 Initiated Canaccord Genuity Buy
Mar-13-19 Initiated Ladenburg Thalmann Buy
Sep-07-18 Resumed Morgan Stanley Overweight
Jun-25-18 Reiterated Needham Buy
Jun-15-18 Reiterated Needham Buy
Oct-30-17 Initiated BofA/Merrill Buy
Oct-30-17 Initiated Needham Buy
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Rhythm Pharmaceuticals Inc Stock (RYTM) Latest News

pulisher
05:15 AM

Rhythm Pharmaceuticals Inc (RYTM) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

05:15 AM
pulisher
01:59 AM

Rhythm Pharmaceuticals Inc (RYTM) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

01:59 AM
pulisher
Jun 18, 2026

Rhythm Pharmaceuticals Inc - TradingKey

Jun 18, 2026
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Jun 17, 2026

Rhythm Pharmaceuticals stock price target reiterated at $130 by TD Cowen By Investing.com - Investing.com South Africa

Jun 17, 2026
pulisher
Jun 17, 2026

RYTM Stock Climbs As PWS Data Drive Analyst Upgrades - StocksToTrade

Jun 17, 2026
pulisher
Jun 17, 2026

Palatin Technologies Is Pursuing the Next Generation of MC4R. Rhythm Just Reinforced Why That Matters - Benzinga

Jun 17, 2026
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Jun 17, 2026

(RYTM) as a Liquidity Pulse for Institutional Tactics - Stock Traders Daily

Jun 17, 2026
pulisher
Jun 17, 2026

Rhythm Pharmaceuticals Inc (RYTM) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Rhythm Pharmaceuticals Inc (RYTM) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jun 17, 2026
pulisher
Jun 17, 2026

Rhythm Pharmaceuticals Inc (RYTM) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jun 17, 2026
pulisher
Jun 17, 2026

Rhythm Pharmaceuticals stock price target reiterated at $130 by TD Cowen - Investing.com South Africa

Jun 17, 2026
pulisher
Jun 16, 2026

symbol__ Stock Quote Price and Forecast - CNN

Jun 16, 2026
pulisher
Jun 16, 2026

Canaccord raises Rhythm Pharmaceuticals price target on trial data By Investing.com - Investing.com South Africa

Jun 16, 2026
pulisher
Jun 16, 2026

Rhythm Pharmaceuticals: Buy Rating Reaffirmed as Strong PWS Data Lift 2033 Outlook and Price Target Raised to $151 from $143 - TipRanks

Jun 16, 2026
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Jun 16, 2026

Rhythm Pharmaceuticals posts long-term setmelanotide data for obesity - Proactive financial news

Jun 16, 2026
pulisher
Jun 16, 2026

Canaccord raises Rhythm Pharmaceuticals price target on trial data - Investing.com

Jun 16, 2026
pulisher
Jun 16, 2026

Citizens reiterates Rhythm Pharmaceuticals stock rating on bivamelagon data - Investing.com

Jun 16, 2026
pulisher
Jun 16, 2026

Citizens reiterates Rhythm Pharmaceuticals stock rating on bivamelagon data By Investing.com - Investing.com Canada

Jun 16, 2026
pulisher
Jun 15, 2026

Rhythm presents data on obesity treatments at endocrine meeting - Investing.com UK

Jun 15, 2026
pulisher
Jun 15, 2026

Rhythm presents data on obesity treatments at endocrine meeting By Investing.com - Investing.com South Africa

Jun 15, 2026
pulisher
Jun 15, 2026

Rhythm builds case for Phase III in Prader-Willi - biocentury.com

Jun 15, 2026
pulisher
Jun 15, 2026

How This Biotech Is Taking On Genetic Obesity — And Winning - Investor's Business Daily

Jun 15, 2026
pulisher
Jun 15, 2026

Rhythm Showcases Positive Setmelanotide Data Across Obesity Trials - TipRanks

Jun 15, 2026
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Jun 15, 2026

Rhythm Pharmaceuticals Announces Multiple New Data Presentations from MC4R Agonists in Acquired Hypothalamic Obesity (HO), Bardet-Biedl Syndrome (BBS) and Prader-Willi Syndrome (PWS) at ENDO 2026 - The Manila Times

Jun 15, 2026
pulisher
Jun 15, 2026

Rhythm Pharmaceuticals (RYTM) reports strong MC4R obesity data across PWS, HO and BBS at ENDO 2026 - Stock Titan

Jun 15, 2026
pulisher
Jun 15, 2026

Rhythm Pharmaceuticals Announces Multiple New Data Presentations From Mc4r Agonists - TradingView

Jun 15, 2026
pulisher
Jun 15, 2026

Rhythm trial finds up to 38% BMI drop in complex rare obesity cases - Stock Titan

Jun 15, 2026
pulisher
Jun 15, 2026

Why Is Rhythm Pharma Stock Jumping Today? - Benzinga

Jun 15, 2026
pulisher
Jun 15, 2026

Stifel reiterates Rhythm Pharmaceuticals stock rating on PWS data By Investing.com - Investing.com Canada

Jun 15, 2026
pulisher
Jun 15, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: Promising Upside Amidst Strong Buy Ratings - DirectorsTalk Interviews

Jun 15, 2026
pulisher
Jun 15, 2026

Rhythm Pharmaceuticals Inc (RYTM) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jun 15, 2026
pulisher
Jun 14, 2026

Rhythm Pharmaceuticals (RYTM) Announces Positive Phase 2 Trial R - GuruFocus

Jun 14, 2026
pulisher
Jun 14, 2026

Rhythm Pharmaceuticals (RYTM) Stock After Positive Phase 2 PWS Data What Does The Valuation Suggest - Sahm

Jun 14, 2026
pulisher
Jun 13, 2026

Rhythm Pharmaceuticals reports phase 2 PWS trial results By Investing.com - Investing.com Canada

Jun 13, 2026
pulisher
Jun 13, 2026

Rhythm Pharmaceuticals reports phase 2 PWS trial results - Investing.com

Jun 13, 2026
pulisher
Jun 13, 2026

Rhythm Pharmaceuticals Presents Positive Interim Six-month Data from Phase 2 Trial of Setmelanotide in Patients with Prader-Willi Syndrome (PWS) at ENDO 2026 - The Manila Times

Jun 13, 2026
pulisher
Jun 13, 2026

Rhythm Pharmaceuticals Says Six-Month Data Shows Setmelanotide Improves Multiple Endpoints In Pws - TradingView

Jun 13, 2026
pulisher
Jun 13, 2026

Experimental PWS drug cuts body fat and hunger in small six-month trial - Stock Titan

Jun 13, 2026
pulisher
Jun 12, 2026

Rhythm Pharmaceuticals Reports Positive Phase 2 Results for PWS Treatment - Intellectia AI

Jun 12, 2026
pulisher
Jun 12, 2026

Rhythm Pharmaceuticals to Announce Interim Six-Month Phase 2 Results Evaluating Setmelanotide in Patients with Prader-Willi Syndrome - Yahoo Finance UK

Jun 12, 2026
pulisher
Jun 11, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) reports Q1 loss, tops revenue estimates - MSN

Jun 11, 2026
pulisher
Jun 09, 2026

RYTM Technical Analysis & Stock Price Forecast - Intellectia AI

Jun 09, 2026
pulisher
Jun 08, 2026

RYTM: ENDO to feature key Praloretel and RM-718 data as HO launch gains momentum in rare disease space - TradingView

Jun 08, 2026
pulisher
Jun 08, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: Exploring a 59.95% Potential Upside in the Biotech Sector - DirectorsTalk Interviews

Jun 08, 2026
pulisher
Jun 08, 2026

Long term debt to total assets ratio of Rhythm Pharmaceuticals, Inc. – XETR:1RV - TradingView

Jun 08, 2026
pulisher
Jun 07, 2026

EBITDA per share of Rhythm Pharmaceuticals, Inc. – XETR:1RV - TradingView

Jun 07, 2026
pulisher
Jun 07, 2026

How Investors May Respond To Rhythm Pharmaceuticals (RYTM) Updating Its Bardet-Biedl Diagnosis Algorithm - Yahoo Finance

Jun 07, 2026
pulisher
Jun 07, 2026

Book value per share of Rhythm Pharmaceuticals, Inc. – XETR:1RV - TradingView

Jun 07, 2026
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Jun 06, 2026

Quick ratio of Rhythm Pharmaceuticals, Inc. – XETR:1RV - TradingView

Jun 06, 2026
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Jun 06, 2026

EBIT per share of Rhythm Pharmaceuticals, Inc. – XETR:1RV - TradingView

Jun 06, 2026
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Jun 06, 2026

Rhythm Pharmaceuticals, Inc. Balance Sheet – XETR:1RV - TradingView

Jun 06, 2026

Rhythm Pharmaceuticals Inc Stock (RYTM) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Rhythm Pharmaceuticals Inc Stock (RYTM) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
German Christopher Paul
Corporate Controller & CAO
May 15 '26
Option Exercise
42.17
4,442
187,313
4,643
German Christopher Paul
Corporate Controller & CAO
May 15 '26
Sale
92.21
4,643
428,131
0
German Christopher Paul
Corporate Controller & CAO
Mar 04 '26
Option Exercise
17.97
1,500
26,955
5,753
German Christopher Paul
Corporate Controller & CAO
Mar 04 '26
Sale
89.56
5,614
502,790
160
$31.43
price up icon 0.74%
$90.89
price down icon 1.44%
$52.96
price down icon 1.38%
$63.96
price up icon 3.50%
ONC ONC
$270.15
price up icon 2.84%
$162.99
price up icon 3.31%
Cap:     |  Volume (24h):