99.25
price down icon6.14%   -6.49
after-market After Hours: 98.42 -0.83 -0.84%
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Rhythm Pharmaceuticals Inc stock is traded at $99.25, with a volume of 447.07K. It is down -6.14% in the last 24 hours and down -10.61% over the past month. Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
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Previous Close:
$105.74
Open:
$105.74
24h Volume:
447.07K
Relative Volume:
0.58
Market Cap:
$6.81B
Revenue:
$217.17M
Net Income/Loss:
$-202.68M
P/E Ratio:
-43.10
EPS:
-2.3028
Net Cash Flow:
$-156.63M
1W Performance:
-2.79%
1M Performance:
-10.61%
6M Performance:
-3.19%
1Y Performance:
+16.45%
1-Day Range:
Value
$98.44
$106.87
1-Week Range:
Value
$98.44
$110.99
52-Week Range:
Value
$74.50
$122.20

Rhythm Pharmaceuticals Inc Stock (RYTM) Company Profile

Name
Name
Rhythm Pharmaceuticals Inc
Name
Phone
857-264-4280
Name
Address
222 BERKELEY STREET, BOSTON, MA
Name
Employee
414
Name
Twitter
@rhythmpharma
Name
Next Earnings Date
2026-08-04
Name
Latest SEC Filings
Name
RYTM's Discussions on Twitter

Compare RYTM vs VRTX, REGN, ARGX, RVMD, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
RYTM icon
RYTM
Rhythm Pharmaceuticals Inc
99.25 7.28B 217.17M -202.68M -156.63M -2.3028
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
477.10 121.57B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
762.63 69.95B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
853.82 55.61B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
187.53 39.98B 742.00K -1.37B -1.07B -7.0731
ONC icon
ONC
Beone Medicines Ltd Adr
316.01 33.81B 5.76B 514.49M 1.10B 4.4813

Rhythm Pharmaceuticals Inc Stock (RYTM) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-19-26 Initiated RBC Capital Mkts Outperform
Nov-25-25 Initiated Citigroup Buy
Nov-05-25 Downgrade Oppenheimer Outperform → Perform
Jul-10-25 Initiated Goldman Buy
Jul-07-25 Initiated Leerink Partners Outperform
Apr-07-25 Upgrade BofA Securities Neutral → Buy
Mar-05-25 Resumed Stifel Buy
Jan-02-25 Initiated Jefferies Buy
Dec-20-24 Initiated Oppenheimer Outperform
Oct-21-24 Initiated Guggenheim Buy
Sep-18-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated JMP Securities Mkt Outperform
May-08-24 Downgrade BofA Securities Buy → Neutral
Dec-19-23 Upgrade Morgan Stanley Equal-Weight → Overweight
Aug-01-23 Upgrade BofA Securities Neutral → Buy
Jan-18-23 Resumed Canaccord Genuity Buy
Aug-08-22 Upgrade Goldman Neutral → Buy
Aug-05-22 Upgrade BofA Securities Underperform → Neutral
Jun-17-22 Reiterated Needham Buy
Mar-02-22 Resumed Stifel Buy
Feb-17-22 Upgrade Ladenburg Thalmann Neutral → Buy
Dec-08-21 Initiated Wells Fargo Overweight
Nov-19-21 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-14-21 Resumed Goldman Neutral
Aug-04-21 Downgrade BofA Securities Neutral → Underperform
Aug-04-21 Downgrade Ladenburg Thalmann Buy → Neutral
Nov-30-20 Downgrade BofA Securities Buy → Neutral
Jan-08-20 Initiated Goldman Sell
Jul-12-19 Upgrade Stifel Hold → Buy
Jul-08-19 Initiated Canaccord Genuity Buy
Mar-13-19 Initiated Ladenburg Thalmann Buy
Sep-07-18 Resumed Morgan Stanley Overweight
Jun-25-18 Reiterated Needham Buy
Jun-15-18 Reiterated Needham Buy
Oct-30-17 Initiated BofA/Merrill Buy
Oct-30-17 Initiated Needham Buy
View All

Rhythm Pharmaceuticals Inc Stock (RYTM) Latest News

pulisher
Jul 28, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Expected to Beat Earnings Estimates: What to Know Ahead of Q2 Release - Yahoo! Finance Canada

Jul 28, 2026
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Jul 28, 2026

Rhythm Pharmaceuticals Inc (RYTM) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jul 28, 2026
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Jul 27, 2026

Rhythm Pharmaceuticals Inc (RYTM) Cash Flow - TradingKey

Jul 27, 2026
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Jul 27, 2026

RYTM Initiated Coverage by JP Morgan -- Rating Overweight with $145 PT - GuruFocus

Jul 27, 2026
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Jul 27, 2026

RYTM|Rhythm Pharmaceuticals Inc|Price:106.150|Chg%:+4.050 - TradingKey

Jul 27, 2026
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Jul 27, 2026

RHYTHM PHARMACEUTICALS INC : JP MORGAN INITIATES COVERAGE WITH OVERWEIGHT RATING; PRICE TARGET $145 - Bitget

Jul 27, 2026
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Jul 27, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: Evaluating A Potential 35% Upside - DirectorsTalk Interviews

Jul 27, 2026
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Jul 27, 2026

Rhythm Pharmaceuticals Inc - TradingKey

Jul 27, 2026
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Jul 27, 2026

JPMorgan initiates Rhythm Pharmaceuticals stock at Overweight By Investing.com - Investing.com Canada

Jul 27, 2026
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Jul 27, 2026

Rhythm Pharmaceuticals Inc (RYTM) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jul 27, 2026
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Jul 25, 2026

Rhythm Pharmaceuticals (RYTM) Q1 2023 Earnings ReportResults, Call & Slides - TipRanks

Jul 25, 2026
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Jul 25, 2026

Rhythm Pharmaceuticals, Inc. Revenue Breakdown – FWB:1RV - TradingView

Jul 25, 2026
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Jul 25, 2026

Rhythm Pharmaceuticals (RYTM) Q3 2023 Earnings ReportResults, Call & Slides - TipRanks

Jul 25, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Q3 2025 Earnings ReportResults, Call & Slides - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Q1 2026 Earnings ReportResults, Call & Slides - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Q4 2024 Earnings ReportResults, Call & Slides - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Q4 2023 Earnings ReportResults, Call & Slides - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Q2 2023 Earnings ReportResults, Call & Slides - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Q1 2025 Earnings ReportResults, Call & Slides - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Q4 2025 Earnings ReportResults, Call & Slides - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Q3 2024 Earnings ReportResults, Call & Slides - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Q1 2024 Earnings ReportResults, Call & Slides - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals (RYTM) Earnings Dates, Call Summary & Reports - TipRanks

Jul 24, 2026
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Jul 24, 2026

Rhythm Pharmaceuticals Inc (RYTM) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jul 24, 2026
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Jul 22, 2026

Rhythm Pharmaceuticals Inc (RYTM) Q3 2024 Earnings ReportResults, Call & Slides - TipRanks

Jul 22, 2026
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Jul 22, 2026

Rhythm Pharmaceuticals (RYTM) Q2 2024 Earnings ReportResults, Call & Slides - TipRanks

Jul 22, 2026
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Jul 22, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) stock price, news, quote and history - Yahoo Finance UK

Jul 22, 2026
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Jul 21, 2026

Kuehn Law Encourages Investors of Rhythm Pharmaceuticals, Inc. to Contact Law Firm - Morningstar

Jul 21, 2026
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Jul 21, 2026

RYTM stock trades around recent range as Rhythm Pharmaceuticals highlights setmelanotide growth - Ad-hoc-news.de

Jul 21, 2026
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Jul 21, 2026

Rhythm Pharmaceuticals to Report Second Quarter 2026 Financial Results on Tuesday, August 4, 2026 - The Manila Times

Jul 21, 2026
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Jul 21, 2026

Rhythm Pharmaceuticals schedules live Q2 results webcast Aug. 4 - Stock Titan

Jul 21, 2026
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Jul 20, 2026

Price-Driven Insight from (RYTM) for Rule-Based Strategy - Stock Traders Daily

Jul 20, 2026
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Jul 20, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Investor Outlook: Strong Buy Ratings Signal Potential 31% Upside - DirectorsTalk Interviews

Jul 20, 2026
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Jul 18, 2026

Rhythm Pharmaceuticals Inc at Bank of America Global Healthcare Conference Transcript - GuruFocus

Jul 18, 2026
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Jul 18, 2026

Rhythm Pharmaceuticals Inc to Discuss Interim Six-Month Phase 2 Results Evaluating Setmelanotide Call Transcript - GuruFocus

Jul 18, 2026
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Jul 16, 2026

Law firm probes Rhythm Pharmaceuticals officers for possible self-dealing harming shareholders - Pluang

Jul 16, 2026
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Jul 16, 2026

Kuehn Law Encourages Investors of Rhythm Pharmaceuticals, Inc. to Contact Law Firm - GlobeNewswire Inc.

Jul 16, 2026
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Jul 16, 2026

Wells Fargo Maintains Rhythm Pharmaceuticals(RYTM.US) With Buy Rating, Maintains Target Price $155 - Moomoo

Jul 16, 2026
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Jul 15, 2026

symbol__ Stock Quote Price and Forecast - CNN

Jul 15, 2026
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Jul 14, 2026

Enterprise value to revenue forward of Rhythm Pharmaceuticals, Inc. – BMV:RYTM - TradingView

Jul 14, 2026
pulisher
Jul 14, 2026

Does NEJM-Validated TRANSCEND Data on Setmelanotide Reshape the Bull Case for Rhythm Pharmaceuticals (RYTM)? - Sahm

Jul 14, 2026
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Jul 14, 2026

Rhythm Pharmaceuticals (RYTM) Edges Higher, Nears Key Resistance LevelSymmetrical Triangle - dars.gov.et

Jul 14, 2026
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Jul 14, 2026

Citizens reiterates Rhythm Pharmaceuticals stock rating on strong Imcivree launch data - Investing.com Canada

Jul 14, 2026
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Jul 13, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: Exploring a 28.91% Upside Potential in Biotechnology - DirectorsTalk Interviews

Jul 13, 2026
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Jul 12, 2026

Enterprise value to EBITDA forward of Rhythm Pharmaceuticals, Inc. – NASDAQ:RYTM - TradingView

Jul 12, 2026
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Jul 12, 2026

Price to earnings forward of Rhythm Pharmaceuticals, Inc. – NASDAQ:RYTM - TradingView

Jul 12, 2026
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Jul 09, 2026

Enterprise value to revenue forward of Rhythm Pharmaceuticals, Inc. – XETR:1RV - TradingView

Jul 09, 2026
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Jul 09, 2026

Analysts Offer Insights on Healthcare Companies: Rhythm Pharmaceuticals (RYTM) and Travere Therapeutics (TVTX) - The Globe and Mail

Jul 09, 2026
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Jul 08, 2026

Rhythm Pharmaceuticals Inc. announced that the results of its Phase 3 Transcend clinical trial for acquired hypothalamic obesity have been published in the top international medical journal, The New England Journal of Medicine. - Bitget

Jul 08, 2026
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Jul 08, 2026

Rhythm Pharmaceuticals Announces NEJM Publication of Phase 3 TRANSCEND Trial Results for Setmelanotide in Acquired Hypothalamic Obesity - Quiver Quantitative

Jul 08, 2026
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Jul 08, 2026

Rhythm Pharmaceuticals Announces The New England Journal of - GlobeNewswire

Jul 08, 2026

Rhythm Pharmaceuticals Inc Stock (RYTM) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Rhythm Pharmaceuticals Inc Stock (RYTM) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
TETRAULT LYNN A.
Director
Jun 22 '26
Sale
100.32
37,000
3,711,896
7,000
$90.58
price down icon 2.44%
$119.52
price down icon 2.82%
$33.91
price down icon 1.77%
$58.43
price down icon 1.00%
$205.52
price up icon 0.02%
ONC ONC
$316.01
price down icon 1.88%
Cap:     |  Volume (24h):