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Rhythm Pharmaceuticals Inc stock is traded at $104.71, with a volume of 573.72K. It is up +2.46% in the last 24 hours and down -7.21% over the past month. Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
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Previous Close:
$102.20
Open:
$102.96
24h Volume:
573.72K
Relative Volume:
0.78
Market Cap:
$7.21B
Revenue:
$217.17M
Net Income/Loss:
$-202.68M
P/E Ratio:
-45.47
EPS:
-2.3028
Net Cash Flow:
$-156.63M
1W Performance:
+1.92%
1M Performance:
-7.21%
6M Performance:
+16.32%
1Y Performance:
+6.93%
1-Day Range:
Value
$102.25
$106.57
1-Week Range:
Value
$99.41
$106.57
52-Week Range:
Value
$74.50
$122.20

Rhythm Pharmaceuticals Inc Stock (RYTM) Company Profile

Name
Name
Rhythm Pharmaceuticals Inc
Name
Phone
857-264-4280
Name
Address
222 BERKELEY STREET, BOSTON, MA
Name
Employee
414
Name
Twitter
@rhythmpharma
Name
Next Earnings Date
2026-11-03
Name
Latest SEC Filings
Name
RYTM's Discussions on Twitter

Compare RYTM vs VRTX, REGN, ARGX, MRNA, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
RYTM icon
RYTM
Rhythm Pharmaceuticals Inc
104.71 7.21B 217.17M -202.68M -156.63M -2.3028
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
515.44 130.64B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
781.49 80.46B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
984.39 61.58B 4.16B 1.29B 734.26M 19.58
MRNA icon
MRNA
Moderna Inc
143.97 57.48B 2.23B -3.19B -1.60B -8.1462
RVMD icon
RVMD
Revolution Medicines Inc
203.77 43.68B 742.00K -1.37B -1.07B -7.0731

Rhythm Pharmaceuticals Inc Stock (RYTM) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-19-26 Initiated RBC Capital Mkts Outperform
Nov-25-25 Initiated Citigroup Buy
Nov-05-25 Downgrade Oppenheimer Outperform → Perform
Jul-10-25 Initiated Goldman Buy
Jul-07-25 Initiated Leerink Partners Outperform
Apr-07-25 Upgrade BofA Securities Neutral → Buy
Mar-05-25 Resumed Stifel Buy
Jan-02-25 Initiated Jefferies Buy
Dec-20-24 Initiated Oppenheimer Outperform
Oct-21-24 Initiated Guggenheim Buy
Sep-18-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated JMP Securities Mkt Outperform
May-08-24 Downgrade BofA Securities Buy → Neutral
Dec-19-23 Upgrade Morgan Stanley Equal-Weight → Overweight
Aug-01-23 Upgrade BofA Securities Neutral → Buy
Jan-18-23 Resumed Canaccord Genuity Buy
Aug-08-22 Upgrade Goldman Neutral → Buy
Aug-05-22 Upgrade BofA Securities Underperform → Neutral
Jun-17-22 Reiterated Needham Buy
Mar-02-22 Resumed Stifel Buy
Feb-17-22 Upgrade Ladenburg Thalmann Neutral → Buy
Dec-08-21 Initiated Wells Fargo Overweight
Nov-19-21 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-14-21 Resumed Goldman Neutral
Aug-04-21 Downgrade BofA Securities Neutral → Underperform
Aug-04-21 Downgrade Ladenburg Thalmann Buy → Neutral
Nov-30-20 Downgrade BofA Securities Buy → Neutral
Jan-08-20 Initiated Goldman Sell
Jul-12-19 Upgrade Stifel Hold → Buy
Jul-08-19 Initiated Canaccord Genuity Buy
Mar-13-19 Initiated Ladenburg Thalmann Buy
Sep-07-18 Resumed Morgan Stanley Overweight
Jun-25-18 Reiterated Needham Buy
Jun-15-18 Reiterated Needham Buy
Oct-30-17 Initiated BofA/Merrill Buy
Oct-30-17 Initiated Needham Buy
View All

Rhythm Pharmaceuticals Inc Stock (RYTM) Latest News

pulisher
Sep 10, 2026

Obesity Market to Witness Strong Growth and Significant Market Expansion by 2036 – DelveInsight | Rhythm Pharma, Boehringer Ingelheim, D&D Pharmatech, ProQR Therapeutics, Nano Precision Medical - Barchart.com

Sep 10, 2026
pulisher
Sep 10, 2026

Exploring 3 High Growth Tech Stocks In The US Market - simplywall.st

Sep 10, 2026
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Sep 10, 2026

Rhythm Pharmaceuticals Announces New Data Presentations at the European Society for Paediatric Endocrinology Meeting - manilatimes.net

Sep 10, 2026
pulisher
Sep 10, 2026

French children showed lower body-size scores on a rare-obesity drug - Stock Titan

Sep 10, 2026
pulisher
Sep 09, 2026

Rhythm Pharmaceuticals at Wells Fargo conference: ho launch gains traction By Investing.com - Investing.com Canada

Sep 09, 2026
pulisher
Sep 07, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: A 36.45% Potential Upside in the Biotech Arena - DirectorsTalk Interviews

Sep 07, 2026
pulisher
Sep 03, 2026

An AI drug specialist zeroes in on rare forms of obesity - BioPharma Dive

Sep 03, 2026
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Sep 02, 2026

Here’s How Much You Would Have Made Owning Rhythm Pharmaceuticals Stock In The Last 5 Years - Benzinga

Sep 02, 2026
pulisher
Sep 02, 2026

Rhythm Pharmaceuticals stock edges lower after insider sale but stays backed by strong Q2 growth - AD HOC NEWS

Sep 02, 2026
pulisher
Sep 02, 2026

How Rhythm Pharmaceuticals Inc. (RYTM) Affects Rotational Strategy Timing - Stock Traders Daily

Sep 02, 2026
pulisher
Sep 01, 2026

Rhythm Pharmaceuticals(RYTM.US) Officer Sells US$6.62 Million in Common Stock - Moomoo

Sep 01, 2026
pulisher
Sep 01, 2026

Rhythm Pharmaceuticals (RYTM) CFO sells 62,774 shares in planned trade - Stock Titan

Sep 01, 2026
pulisher
Aug 31, 2026

Rhythm (NASDAQ: RYTM) officer files Rule 144 stock sale notice - Stock Titan

Aug 31, 2026
pulisher
Aug 31, 2026

Here's How Much $100 Invested In Rhythm Pharmaceuticals 5 Years Ago Would Be Worth Today - Benzinga

Aug 31, 2026
pulisher
Aug 31, 2026

Rhythm Pharmaceuticals (RYTM): Investor Outlook on a 30.81% Potential Upside in Biotechnology - DirectorsTalk Interviews

Aug 31, 2026
pulisher
Aug 31, 2026

Rhythm Pharmaceuticals Inc. (RYTM) Financials – Balance Sheet, Profit & Loss, Cash Flow - Value Research

Aug 31, 2026
pulisher
Aug 29, 2026

RHYTHM PHARMACEUTICALS, INC. : DEUTSCHE BANK INITIATES COVERAGE WITH HOLD RATING AND TARGET PRICE $120 - webull.com

Aug 29, 2026
pulisher
Aug 29, 2026

Deutsche Bank Initiates Rhythm Pharmaceuticals(RYTM.US) With Hold Rating, Announces Target Price $120 - Moomoo

Aug 29, 2026
pulisher
Aug 28, 2026

Deutsche Bank Initiates Rhythm Pharmaceuticals at Hold With $120 Price Target - marketscreener.com

Aug 28, 2026
pulisher
Aug 27, 2026

Rhythm Pharmaceuticals (RYTM) Could Be 15% Undervalued As Japan Approval Lifts Its Story - sahmcapital.com

Aug 27, 2026
pulisher
Aug 27, 2026

Rhythm Pharmaceuticals Gains Japan Approval For IMCIVREE In Hypothalamic Obesity - DirectorsTalk Interviews

Aug 27, 2026
pulisher
Aug 26, 2026

Rhythm Pharmaceuticals (RYTM) Stock Looks Overvalued Despite Its 7x Five Year Run - Yahoo Finance

Aug 26, 2026
pulisher
Aug 24, 2026

Rhythm Pharmaceuticals Announces MHLW Approval of IMCIVREE® (setmelanotide) for Patients with Acquired Hypothalamic Obesity (HO) in Japan - The Manila Times

Aug 24, 2026
pulisher
Aug 24, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: Biotechnology Innovator Seeks 28.67% Upside with Breakthrough Therapies - DirectorsTalk Interviews

Aug 24, 2026
pulisher
Aug 24, 2026

*Rhythm Pharmaceuticals: Commercial Launch in Japan Expected by End of 2026, Pending Final Pricing Determination >RYTM - webull.com

Aug 24, 2026
pulisher
Aug 23, 2026

Eli Lilly and Novo Nordisk Can't Treat This Form of Obesity. Billionaire Stanley Druckenmiller Is Betting Rhythm Pharmaceuticals Can - Yahoo Finance

Aug 23, 2026
pulisher
Aug 21, 2026

Blue Owl Capital Holdings LP Invests $6.82 Million in Rhythm Pharmaceuticals, Inc. $RYTM - MarketBeat

Aug 21, 2026
pulisher
Aug 20, 2026

TD Cowen Names Rhythm Pharmaceuticals Its Top Pick Following Robust Q2 Results - StockInvest.us

Aug 20, 2026
pulisher
Aug 18, 2026

Rhythm Pharmaceuticals (RYTM) grants CMO 50K options expiring 2036 - Stock Titan

Aug 18, 2026
pulisher
Aug 18, 2026

Rhythm (RYTM) CMO reports no company stock holdings - Stock Titan

Aug 18, 2026
pulisher
Aug 18, 2026

Rhythm Pharmaceuticals (RYTM) Stock Looks Pricey Following Strong IMCIVREE News - Sahm

Aug 18, 2026
pulisher
Aug 18, 2026

Rhythm Pharmaceuticals Announces Appointment of Manher (AJ) Joshi as Chief Medical Officer - Sahm

Aug 18, 2026
pulisher
Aug 18, 2026

Rhythm Pharmaceuticals: Building A Defensive MC4R Franchise (NASDAQ:RYTM) - Seeking Alpha

Aug 18, 2026
pulisher
Aug 17, 2026

Rhythm Pharmaceuticals CSO Alastair Garfield sells $912,703 in stock By Investing.com - Investing.com Canada

Aug 17, 2026
pulisher
Aug 17, 2026

Rhythm Pharmaceuticals CTO Joseph Shulman sells $608,210 of stock - Investing.com

Aug 17, 2026
pulisher
Aug 17, 2026

Rhythm Pharmaceuticals CTO Joseph Shulman sells $608,210 of stock By Investing.com - Investing.com India

Aug 17, 2026
pulisher
Aug 17, 2026

Rhythm Pharmaceuticals (NASDAQ:RYTM) Insider Alastair Garfield Sells 7,763 Shares - MarketBeat

Aug 17, 2026
pulisher
Aug 17, 2026

Insider Selling: Rhythm Pharmaceuticals (NASDAQ:RYTM) Insider Sells 5,079 Shares of Stock - MarketBeat

Aug 17, 2026
pulisher
Aug 17, 2026

Rhythm Pharmaceuticals CSO Alastair Garfield sells $912,703 in stock - Investing.com

Aug 17, 2026
pulisher
Aug 17, 2026

Rhythm (NASDAQ: RYTM) CTO sells 5,079 shares in 10b5-1 plan - Stock Titan

Aug 17, 2026
pulisher
Aug 17, 2026

Rhythm Pharmaceuticals Eyes AHO Growth, Global IMCIVREE Expansion and Pipeline Catalysts - NewsBreak: Local News & Alerts

Aug 17, 2026
pulisher
Aug 17, 2026

Rhythm Pharmaceuticals Announces Appointment Of Manher (Aj) Joshi As Chief Medical Officer - TradingView

Aug 17, 2026
pulisher
Aug 17, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Stock Analysis: Exploring a 22.56% Potential Upside on Robust Analyst Confidence - DirectorsTalk Interviews

Aug 17, 2026
pulisher
Aug 16, 2026

Enterprise value to revenue forward of Rhythm Pharmaceuticals, Inc. – DUS:1RV - TradingView

Aug 16, 2026
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Aug 15, 2026

Rhythm Pharmaceuticals(RYTM.US) Officer Sells US$8.9 Million in Common Stock - Moomoo

Aug 15, 2026
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Aug 15, 2026

Rhythm Pharmaceuticals EVP Mazabraud sells $6.6m in stock By Investing.com - Investing.com Nigeria

Aug 15, 2026
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Aug 15, 2026

Rhythm Pharmaceuticals EVP, Jennifer Lee, sells $8.9m in stock By Investing.com - Investing.com UK

Aug 15, 2026
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Aug 14, 2026

Rhythm Pharmaceuticals EVP Jennifer Kayden Lee Executes Stock Options and Sells Shares Under 10b5-1 Plan - Kalkine Media

Aug 14, 2026
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Aug 14, 2026

Rhythm Pharmaceuticals EVP Yann Mazabraud Executes Stock Option and Sells Shares Under Rule 10b5-1 Plan - Kalkine Media

Aug 14, 2026
pulisher
Aug 14, 2026

Rhythm Pharmaceuticals (NASDAQ:RYTM) EVP Yann Mazabraud Sells 57,000 Shares - MarketBeat

Aug 14, 2026
pulisher
Aug 14, 2026

Insider Selling: Rhythm Pharmaceuticals (NASDAQ:RYTM) EVP Sells 75,834 Shares of Stock - MarketBeat

Aug 14, 2026

Rhythm Pharmaceuticals Inc Stock (RYTM) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$58.61
price down icon 0.24%
$129.41
price up icon 1.67%
$40.82
price down icon 0.29%
$248.68
price up icon 0.47%
ONC ONC
$346.51
price up icon 1.38%
$203.77
price up icon 0.21%
Cap:     |  Volume (24h):