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Rhythm Pharmaceuticals Inc stock is traded at $84.43, with a volume of 172.05K. It is down -3.66% in the last 24 hours and down -16.61% over the past month. Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
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Previous Close:
$87.68
Open:
$86.21
24h Volume:
172.05K
Relative Volume:
0.22
Market Cap:
$5.77B
Revenue:
$189.76M
Net Income/Loss:
$-196.54M
P/E Ratio:
-27.16
EPS:
-3.1087
Net Cash Flow:
$-156.63M
1W Performance:
-6.17%
1M Performance:
-16.61%
6M Performance:
-14.28%
1Y Performance:
+61.54%
1-Day Range:
Value
$84.02
$87.25
1-Week Range:
Value
$82.00
$92.69
52-Week Range:
Value
$45.91
$122.20

Rhythm Pharmaceuticals Inc Stock (RYTM) Company Profile

Name
Name
Rhythm Pharmaceuticals Inc
Name
Phone
857-264-4280
Name
Address
222 BERKELEY STREET, BOSTON, MA
Name
Employee
414
Name
Twitter
@rhythmpharma
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
RYTM's Discussions on Twitter

Compare RYTM vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
RYTM
Rhythm Pharmaceuticals Inc
84.57 6.18B 189.76M -196.54M -156.63M -3.1087
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
455.65 118.41B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
745.46 80.02B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
684.73 43.52B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
313.96 42.29B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
281.89 32.13B 5.36B 287.73M 924.18M 2.5229

Rhythm Pharmaceuticals Inc Stock (RYTM) Upgrades & Downgrades

Date Action Analyst Rating Change
Feb-19-26 Initiated RBC Capital Mkts Outperform
Nov-25-25 Initiated Citigroup Buy
Nov-05-25 Downgrade Oppenheimer Outperform → Perform
Jul-10-25 Initiated Goldman Buy
Jul-07-25 Initiated Leerink Partners Outperform
Apr-07-25 Upgrade BofA Securities Neutral → Buy
Mar-05-25 Resumed Stifel Buy
Jan-02-25 Initiated Jefferies Buy
Dec-20-24 Initiated Oppenheimer Outperform
Oct-21-24 Initiated Guggenheim Buy
Sep-18-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated JMP Securities Mkt Outperform
May-08-24 Downgrade BofA Securities Buy → Neutral
Dec-19-23 Upgrade Morgan Stanley Equal-Weight → Overweight
Aug-01-23 Upgrade BofA Securities Neutral → Buy
Jan-18-23 Resumed Canaccord Genuity Buy
Aug-08-22 Upgrade Goldman Neutral → Buy
Aug-05-22 Upgrade BofA Securities Underperform → Neutral
Jun-17-22 Reiterated Needham Buy
Mar-02-22 Resumed Stifel Buy
Feb-17-22 Upgrade Ladenburg Thalmann Neutral → Buy
Dec-08-21 Initiated Wells Fargo Overweight
Nov-19-21 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-14-21 Resumed Goldman Neutral
Aug-04-21 Downgrade BofA Securities Neutral → Underperform
Aug-04-21 Downgrade Ladenburg Thalmann Buy → Neutral
Nov-30-20 Downgrade BofA Securities Buy → Neutral
Jan-08-20 Initiated Goldman Sell
Jul-12-19 Upgrade Stifel Hold → Buy
Jul-08-19 Initiated Canaccord Genuity Buy
Mar-13-19 Initiated Ladenburg Thalmann Buy
Sep-07-18 Resumed Morgan Stanley Overweight
Jun-25-18 Reiterated Needham Buy
Jun-15-18 Reiterated Needham Buy
Oct-30-17 Initiated BofA/Merrill Buy
Oct-30-17 Initiated Needham Buy
View All

Rhythm Pharmaceuticals Inc Stock (RYTM) Latest News

pulisher
07:21 AM

Rhythm Pharmaceuticals: EMANATE Setback but Validated MC4R Mechanism and Pipeline Optionality Support Lowered $100 Buy Rating - TipRanks

07:21 AM
pulisher
07:15 AM

HC Wainwright & Co. Lowers Price Target for Rhythm Pharmaceutica - GuruFocus

07:15 AM
pulisher
05:28 AM

Focus Shifts To Rhythm’s Imcivree Hypothalamic Obesity Opportunity After Phase III Miss - Citeline News & Insights

05:28 AM
pulisher
05:04 AM

A Look At Rhythm Pharmaceuticals (RYTM) Valuation After Recent Share Weakness And Strong Long Term Returns - Yahoo Finance

05:04 AM
pulisher
04:24 AM

Is It Too Late To Consider Rhythm Pharmaceuticals (RYTM) After Its 4x Three Year Surge? - simplywall.st

04:24 AM
pulisher
03:01 AM

Wall Street Recap: Can Rhythm Pharmaceuticals Inc ride the EV waveSwing Trade & Daily Profit Maximizing Tips - baoquankhu1.vn

03:01 AM
pulisher
Mar 17, 2026

Rhythm Pharmaceuticals Inc (RYTM) Stock Price, Quote, News & History - Benzinga

Mar 17, 2026
pulisher
Mar 17, 2026

RYTM: Morgan Stanley Lowers Price Target to $136 While Maintaini - GuruFocus

Mar 17, 2026
pulisher
Mar 17, 2026

Rhythm Pharmaceuticals Misses The Beat In Obesity, But There's A Caveat - Investor's Business Daily

Mar 17, 2026
pulisher
Mar 17, 2026

Rhythm Pharmaceuticals (NASDAQ:RYTM) Price Target Lowered to $131.00 at Citigroup - MarketBeat

Mar 17, 2026
pulisher
Mar 17, 2026

Post-Emanate, Rhythm’s next Imcivree news aHO lot better? - BioWorld MedTech

Mar 17, 2026
pulisher
Mar 17, 2026

Rhythm Pharmaceuticals (NASDAQ:RYTM) Price Target Lowered to $130.00 at Royal Bank Of Canada - MarketBeat

Mar 17, 2026
pulisher
Mar 17, 2026

RBC cuts Rhythm Pharmaceuticals stock price target on trial miss By Investing.com - Investing.com Canada

Mar 17, 2026
pulisher
Mar 17, 2026

Citizens Lowers Price Target for Rhythm Pharmaceuticals (RYTM) While Maintaining Rating | RYTM Stock News - GuruFocus

Mar 17, 2026
pulisher
Mar 17, 2026

Citizens Jmp Cuts Rhythm Pharmaceuticals (NASDAQ:RYTM) Price Target to $152.00 - MarketBeat

Mar 17, 2026
pulisher
Mar 17, 2026

Needham cuts Rhythm Pharmaceuticals stock price target on trial miss By Investing.com - Investing.com Canada

Mar 17, 2026
pulisher
Mar 17, 2026

Rhythm Pharmaceuticals (RYTM) Analyst Rating Update: Price Targe - GuruFocus

Mar 17, 2026
pulisher
Mar 17, 2026

RYTM: Morgan Stanley Lowers Price Target to $136 While Maintaining Overweight Rating | RYTM Stock News - GuruFocus

Mar 17, 2026
pulisher
Mar 17, 2026

Needham & Company LLC Lowers Rhythm Pharmaceuticals (NASDAQ:RYTM) Price Target to $130.00 - MarketBeat

Mar 17, 2026
pulisher
Mar 17, 2026

Morgan Stanley Issues Pessimistic Forecast for Rhythm Pharmaceuticals (NASDAQ:RYTM) Stock Price - MarketBeat

Mar 17, 2026
pulisher
Mar 17, 2026

Rhythm Pharmaceuticals (NASDAQ:RYTM) Given New $139.00 Price Target at Bank of America - MarketBeat

Mar 17, 2026
pulisher
Mar 17, 2026

Stock Market Today: Dow, S&P 500 Futures Tick Up As Oil Prices Rise, US Allies Reject Trump's Hormuz Call— Uber, Lululemon, Cisco In Focus (UPDATED) - Benzinga

Mar 17, 2026
pulisher
Mar 17, 2026

RYTM: Needham Maintains Buy Rating While Lowering Price Target | - GuruFocus

Mar 17, 2026
pulisher
Mar 17, 2026

Rhythm Pharmaceuticals Rare Obesity Drug Study Disappoints - Benzinga

Mar 17, 2026
pulisher
Mar 17, 2026

RBC Lowers Price Target on Rhythm Pharmaceuticals to $130 From $140, Keeps Outperform, Speculative Risk - marketscreener.com

Mar 17, 2026
pulisher
Mar 17, 2026

Rhythm Pharmaceuticals, Inc. $RYTM Shares Bought by Aquatic Capital Management LLC - MarketBeat

Mar 17, 2026
pulisher
Mar 17, 2026

Stocks Showing Improving Market Leadership: Rhythm Pharmaceuticals Earns 81 RS Rating - Investor's Business Daily

Mar 17, 2026
pulisher
Mar 17, 2026

Rhythm Pharmaceuticals, Inc. (RYTM) Discusses Topline Results and Insights from Phase 3 EMANATE TrialSlideshow (NASDAQ:RYTM) 2026-03-17 - Seeking Alpha

Mar 17, 2026
pulisher
Mar 16, 2026

Rhythm Pharma shares fall as obesity drug trial fails to meet main goal - Investing.com South Africa

Mar 16, 2026
pulisher
Mar 16, 2026

Stifel reiterates Rhythm Pharmaceuticals stock rating at buy By Investing.com - Investing.com Canada

Mar 16, 2026
pulisher
Mar 16, 2026

Rhythm Pharmaceuticals Announces Topline Results from Phase 3 EMANATE Trial - Bitget

Mar 16, 2026
pulisher
Mar 16, 2026

Rhythm Pharmaceuticals Reports Mixed Phase 3 EMANATE Results - TipRanks

Mar 16, 2026
pulisher
Mar 16, 2026

Rhythm Pharmaceuticals (RYTM) Shares Results from EMANATE Trial - GuruFocus

Mar 16, 2026
pulisher
Mar 16, 2026

Trust for Rhythm Pharmaceuticals (RYTM) director receives 4,199 shares - Stock Titan

Mar 16, 2026
pulisher
Mar 16, 2026

Rhythm Pharma's obesity drug fails to meet main goal in late-stage trial - marketscreener.com

Mar 16, 2026
pulisher
Mar 16, 2026

Rhythm Pharmaceuticals: Rare Genetic Obesity Player With Upcoming PDUFA (NASDAQ:RYTM) - Seeking Alpha

Mar 16, 2026
pulisher
Mar 16, 2026

Rhythm Pharmaceuticals Q4 Beat Sets Stage For March 20th PDUFA Decision (NASDAQ:RYTM) - Seeking Alpha

Mar 16, 2026
pulisher
Mar 16, 2026

First Light Asset Management LLC Takes $18.23 Million Position in Rhythm Pharmaceuticals, Inc. $RYTM - MarketBeat

Mar 16, 2026
pulisher
Mar 16, 2026

Cinctive Capital Management LP Sells 35,781 Shares of Rhythm Pharmaceuticals, Inc. $RYTM - MarketBeat

Mar 16, 2026
pulisher
Mar 15, 2026

Checkpoint Capital L.P. Has $77.13 Million Position in Rhythm Pharmaceuticals, Inc. $RYTM - MarketBeat

Mar 15, 2026
pulisher
Mar 15, 2026

Algert Global LLC Increases Stake in Rhythm Pharmaceuticals, Inc. $RYTM - MarketBeat

Mar 15, 2026
pulisher
Mar 14, 2026

Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) Receives Consensus Recommendation of "Moderate Buy" from Analysts - MarketBeat

Mar 14, 2026
pulisher
Mar 14, 2026

Integral Health Asset Management LLC Increases Stock Position in Rhythm Pharmaceuticals, Inc. $RYTM - MarketBeat

Mar 14, 2026
pulisher
Mar 13, 2026

Early FDA, Japan Filings For Setmelanotide In Hypothalamic Obesity Might Change The Case For Investing In Rhythm Pharmaceuticals (RYTM) - Sahm

Mar 13, 2026
pulisher
Mar 12, 2026

Institution Moves: Is Rhythm Pharmaceuticals Inc vulnerable to short sellers2026 Price Targets & Long Hold Capital Preservation Plans - baoquankhu1.vn

Mar 12, 2026
pulisher
Mar 12, 2026

Wells Fargo Maintains Overweight, Raises Price Target for RYTM t - GuruFocus

Mar 12, 2026
pulisher
Mar 12, 2026

Wells Fargo raises Rhythm Pharmaceuticals price target on revenue By Investing.com - Investing.com Australia

Mar 12, 2026
pulisher
Mar 12, 2026

Wells Fargo raises Rhythm Pharmaceuticals price target on revenue - Investing.com

Mar 12, 2026
pulisher
Mar 12, 2026

598,247 Shares in Rhythm Pharmaceuticals, Inc. $RYTM Purchased by Capital Research Global Investors - MarketBeat

Mar 12, 2026
pulisher
Mar 12, 2026

Rhythm Pharmaceuticals discloses 18.8% BMI drop in rare obesity patients - MSN

Mar 12, 2026
pulisher
Mar 11, 2026

FDA Accepts a New Drug Application From Rhythm Pharmaceuticals (RYTM) - MSN

Mar 11, 2026

Rhythm Pharmaceuticals Inc Stock (RYTM) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$45.70
price down icon 0.84%
$27.76
price down icon 1.38%
$51.17
price down icon 4.63%
$93.14
price down icon 1.15%
$142.99
price down icon 0.43%
biotechnology ONC
$284.11
price down icon 1.77%
Cap:     |  Volume (24h):