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Protagonist Therapeutics Inc stock is traded at $138.75, with a volume of 512.65K. It is down -4.23% in the last 24 hours and down -6.36% over the past month. Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
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Previous Close:
$144.88
Open:
$146
24h Volume:
512.65K
Relative Volume:
0.61
Market Cap:
$8.98B
Revenue:
$74.06M
Net Income/Loss:
$-114.71M
P/E Ratio:
-76.92
EPS:
-1.8039
Net Cash Flow:
$-117.90M
1W Performance:
+0.04%
1M Performance:
-6.36%
6M Performance:
+42.21%
1Y Performance:
+75.26%
1-Day Range:
Value
$138.41
$146.00
1-Week Range:
Value
$137.25
$152.19
52-Week Range:
Value
$65.75
$160.81

Protagonist Therapeutics Inc Stock (PTGX) Company Profile

Name
Name
Protagonist Therapeutics Inc
Name
Phone
(510) 474-0170
Name
Address
7707 GATEWAY BLVD., SUITE 140, NEWARK, CA
Name
Employee
132
Name
Twitter
Name
Next Earnings Date
2026-11-05
Name
Latest SEC Filings
Name
PTGX's Discussions on Twitter

Compare PTGX vs VRTX, MRNA, REGN, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PTGX icon
PTGX
Protagonist Therapeutics Inc
138.75 8.98B 74.06M -114.71M -117.90M -1.8039
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
487.48 123.56B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
217.32 86.76B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
752.19 77.44B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
803.03 50.50B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
188.90 40.49B 742.00K -1.37B -1.07B -7.0731

Protagonist Therapeutics Inc Stock (PTGX) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-10-26 Upgrade Goldman Neutral → Buy
May-21-26 Initiated Wolfe Research Outperform
Sep-17-25 Initiated Barclays Overweight
Sep-12-25 Initiated Leerink Partners Outperform
Jun-17-25 Initiated Citigroup Buy
Dec-06-24 Initiated BMO Capital Markets Outperform
Dec-06-24 Initiated Goldman Neutral
Nov-05-24 Initiated Wedbush Outperform
Sep-24-24 Initiated TD Cowen Buy
Sep-09-24 Initiated Truist Buy
Oct-30-23 Initiated CapitalOne Overweight
May-25-23 Resumed Jefferies Buy
Aug-25-22 Initiated JMP Securities Mkt Outperform
Feb-11-22 Initiated BTIG Research Buy
Oct-12-21 Upgrade JP Morgan Neutral → Overweight
Oct-11-21 Upgrade Northland Capital Market Perform → Outperform
Sep-20-21 Downgrade JP Morgan Overweight → Neutral
May-24-21 Initiated JMP Securities Mkt Outperform
May-24-21 Initiated Northland Capital Outperform
Jan-06-21 Initiated JP Morgan Overweight
Dec-16-20 Initiated Piper Sandler Overweight
Sep-18-20 Reiterated H.C. Wainwright Buy
Jul-15-20 Initiated Jefferies Buy
May-18-20 Reiterated H.C. Wainwright Buy
Jul-08-19 Initiated H.C. Wainwright Buy
May-09-19 Upgrade Stifel Hold → Buy
Dec-06-18 Initiated Nomura Buy
Jan-29-18 Initiated Stifel Buy
Jul-21-17 Initiated BTIG Research Buy
View All

Protagonist Therapeutics Inc Stock (PTGX) Latest News

pulisher
Oct 07, 2026

Protagonist Therapeutics, Inc. (PTGX) Stock Forecasts - Yahoo Finance

Oct 07, 2026
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Oct 05, 2026

Protagonist Therapeutics, Inc. (PTGX) Options Chain - Yahoo! Finance Canada

Oct 05, 2026
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Oct 04, 2026

Protagonist Therapeutics, Inc. (PTGX) Options Chain - Yahoo! Finance Canada

Oct 04, 2026
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Oct 03, 2026

Protagonist Therapeutics, Inc. (PTGX) options chain - Yahoo Finance Australia

Oct 03, 2026
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Oct 02, 2026

Protagonist Therapeutics(PTGX.US) Officer Sells US$8.31 Million in Common Stock - Moomoo

Oct 02, 2026
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Oct 02, 2026

Insider Selling: Protagonist Therapeutics (NASDAQ:PTGX) CFO Sells 58,629 Shares of Company Stock - MarketBeat

Oct 02, 2026
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Oct 02, 2026

After exercising options, Protagonist Therapeutics (PTGX) CFO sells 58,629 shares under a trading plan. - stocktitan.net

Oct 02, 2026
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Oct 02, 2026

Protagonist Therapeutics, Inc. (NASDAQ:PTGX) Stock Has Consensus Price Target of $147.13 According to Analysts - MarketBeat

Oct 02, 2026
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Oct 01, 2026

Protagonist Therapeutics, Inc. (PTGX) Stock Forecasts - Yahoo Finance

Oct 01, 2026
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Oct 01, 2026

Form 144 PROTAGONIST THERAPEUTICS For: 1 October By Investing.com - Investing.com Nigeria

Oct 01, 2026
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Sep 30, 2026

Officer Asif Ali plans to sell 58,629 Protagonist Therapeutics (PTGX) shares. - Stock Titan

Sep 30, 2026
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Sep 28, 2026

Here's How Much $100 Invested In Protagonist Therapeutics 10 Years Ago Would Be Worth Today - Benzinga

Sep 28, 2026
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Sep 25, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Shares Gap UpWhat's Next? - MarketBeat

Sep 25, 2026
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Sep 22, 2026

Top Generate Biomedicines (GENB) Competitors 2026 - MarketBeat

Sep 22, 2026
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Sep 21, 2026

Protagonist Therapeutics (Nasdaq:PTGX)Stock Analysis - simplywall.st

Sep 21, 2026
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Sep 18, 2026

1,324,498 Shares in Protagonist Therapeutics, Inc. $PTGX Purchased by Bank of America Corp DE - MarketBeat

Sep 18, 2026
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Sep 16, 2026

PTGX: Protagonist Therapeutics Inc Latest Stock Price, Analysis, News and Trading Ideas - Stocktwits

Sep 16, 2026
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Sep 15, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Combines High Growth Momentum With a Breakout Setup - ChartMill

Sep 15, 2026
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Sep 13, 2026

VIRGINIA RETIREMENT SYSTEMS ET Al Buys Shares of 11,200 Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Sep 13, 2026
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Sep 12, 2026

(PTGX) Movement Within Algorithmic Entry Frameworks - Stock Traders Daily

Sep 12, 2026
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Sep 11, 2026

Protagonist Therapeutics CEO sells $18.2m in shares By Investing.com - Investing.com Australia

Sep 11, 2026
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Sep 11, 2026

Hsbc Holdings PLC Purchases 24,045 Shares of Protagonist Therapeutics, Inc. $PTGX - MarketBeat

Sep 11, 2026
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Sep 11, 2026

Protagonist Therapeutics Insider Sold Shares Worth $18,240,568, According to a Recent SEC Filing - Yahoo Finance

Sep 11, 2026
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Sep 10, 2026

Dinesh Ph Patel Sells 63,548 Shares of Protagonist Therapeutics (NASDAQ:PTGX) Stock - MarketBeat

Sep 10, 2026
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Sep 10, 2026

Insider Selling: Protagonist Therapeutics (NASDAQ:PTGX) CEO Sells 54,174 Shares - MarketBeat

Sep 10, 2026
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Sep 10, 2026

Protagonist Therapeutics CEO sells $18.2m in shares - Investing.com India

Sep 10, 2026
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Sep 10, 2026

Protagonist Therapeutics CEO sells $18.2m in shares By Investing.com - Investing.com UK

Sep 10, 2026
pulisher
Sep 10, 2026

Protagonist Therapeutics (PTGX) CEO sells 125K shares in preset plan - Stock Titan

Sep 10, 2026
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Sep 10, 2026

Protagonist Therapeutics(PTGX.US) Officer Sells US$18.24 Million in Common Stock - Moomoo

Sep 10, 2026
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Sep 10, 2026

Protagonist Therapeutics at Cantor conference: cash, launches and pipeline By Investing.com - Investing.com Nigeria

Sep 10, 2026
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Sep 10, 2026

Protagonist Therapeutics at Cantor conference: cash, launches and pipeline By Investing.com - Investing.com UK

Sep 10, 2026
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Sep 09, 2026

Protagonist Therapeutics, Inc. at Citi Biopharma Back to School Summit Transcript - GuruFocus

Sep 09, 2026
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Sep 09, 2026

Transcript : Protagonist Therapeutics, Inc. Presents at Citigroup?s Biopharma Back to School Summit 2026, Sep-09-2026 10 - marketscreener.com

Sep 09, 2026
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Sep 08, 2026

Protagonist Therapeutics authorizes $300 million buyback plan By Investing.com - Investing.com Nigeria

Sep 08, 2026
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Sep 08, 2026

Protagonist Therapeutics authorizes $300 million buyback plan By Investing.com - Investing.com South Africa

Sep 08, 2026
pulisher
Sep 08, 2026

Protagonist Therapeutics (PTGX) CEO gifts stock to family - Stock Titan

Sep 08, 2026
pulisher
Sep 08, 2026

Protagonist Therapeutics authorizes $300 million buyback plan - investing.com

Sep 08, 2026
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Sep 08, 2026

Protagonist Therapeutics Announces $300 Million Share Repurchase Program - ACCESS Newswire

Sep 08, 2026
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Sep 08, 2026

Protagonist Therapeutics Announces $300 Million Share Repurchase Program - chronicle-tribune.com

Sep 08, 2026
pulisher
Sep 08, 2026

Protagonist Therapeutics Announces $300 Million Share Repurchase Program - marketscreener.com

Sep 08, 2026
pulisher
Sep 08, 2026

News by ACCESS Newswire on TradingView, 2026-09-08 - TradingView

Sep 08, 2026
pulisher
Sep 08, 2026

Up to $300 million could go toward buying back shares at Protagonist Therapeutics. - Stock Titan

Sep 08, 2026
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Sep 08, 2026

Protagonist Therapeutics Announces $300 Million Share Repurchase Program - Yahoo Finance

Sep 08, 2026
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Sep 08, 2026

Protagonist Therapeutics (PTGX) 10K Form and Latest SEC Filings 2026 - MarketBeat

Sep 08, 2026
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Sep 07, 2026

Ulcerative Colitis Market Outlook: 5 Late-Stage Drug Candidates to Watch | DelveInsight - GlobeNewswire Inc.

Sep 07, 2026
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Sep 07, 2026

Protagonist Therapeutics, Inc. (NASDAQ:PTGX) Receives Consensus Recommendation of "Moderate Buy" from Brokerages - MarketBeat

Sep 07, 2026
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Sep 06, 2026

Protagonist (PTGX) Swings To A Profit As Two Drugs Near Blockbuster Status - Yahoo Finance

Sep 06, 2026
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Sep 04, 2026

MIMRYLO Approval Triggered $275M Payments for Protagonist (PTGX). Are Royalties the Better Commercial Model? - Yahoo Finance

Sep 04, 2026
pulisher
Sep 03, 2026

Protagonist Therapeutics (PTGX) Stock Looks Fully Priced After Its 7x Run - simplywall.st

Sep 03, 2026
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Sep 02, 2026

Research Analysts Offer Predictions for PTGX Q1 Earnings - marketbeat.com

Sep 02, 2026

Protagonist Therapeutics Inc Stock (PTGX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Protagonist Therapeutics Inc Stock (PTGX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
ASIF ALI
Officer
Sep 30 '26
Proposed Sale
140.97
58,629
8,264,930
0
Ali Asif
Chief Financial Officer
Sep 30 '26
Sale
141.78
58,629
8,312,294
59,003
PATEL DINESH V PH D
President and CEO
Sep 10 '26
Sale
144.10
7,278
1,048,760
522,968
PATEL DINESH V PH D
President and CEO
Sep 10 '26
Option Exercise
21.58
7,278
157,059
530,246
PATEL DINESH V PH D
President and CEO
Sep 09 '26
Option Exercise
21.58
63,548
1,371,366
586,516
PATEL DINESH V PH D
President and CEO
Sep 09 '26
Sale
146.18
63,548
9,289,447
522,968
PATEL DINESH V PH D
President and CEO
Sep 08 '26
Sale
145.87
54,174
7,902,361
522,968
PATEL DINESH V PH D
President and CEO
Sep 08 '26
Option Exercise
21.58
54,174
1,169,075
577,142
PATEL DINESH V PH D
President and CEO
Aug 11 '26
Sale
148.52
34,239
5,085,176
523,478
PATEL DINESH V PH D
President and CEO
Aug 11 '26
Option Exercise
21.58
34,239
738,878
557,717
$107.26
price down icon 4.30%
$62.09
price down icon 1.11%
$323.75
price down icon 2.50%
CAI CAI
$29.62
price down icon 0.24%
$58.55
price down icon 3.59%
Cap:     |  Volume (24h):