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Protagonist Therapeutics Inc stock is traded at $103.69, with a volume of 7,858. It is up +3.90% in the last 24 hours and up +18.01% over the past month. Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
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Previous Close:
$100.39
Open:
$103.25
24h Volume:
7,858
Relative Volume:
0.01
Market Cap:
$6.62B
Revenue:
$46.02M
Net Income/Loss:
$-130.15M
P/E Ratio:
-50.76
EPS:
-2.0427
Net Cash Flow:
$56.08M
1W Performance:
+2.59%
1M Performance:
+18.01%
6M Performance:
+54.72%
1Y Performance:
+110.47%
1-Day Range:
Value
$103.25
$103.70
1-Week Range:
Value
$97.16
$105.00
52-Week Range:
Value
$39.60
$105.69

Protagonist Therapeutics Inc Stock (PTGX) Company Profile

Name
Name
Protagonist Therapeutics Inc
Name
Phone
(510) 474-0170
Name
Address
7707 GATEWAY BLVD., SUITE 140, NEWARK, CA
Name
Employee
132
Name
Twitter
Name
Next Earnings Date
2026-02-20
Name
Latest SEC Filings
Name
PTGX's Discussions on Twitter

Compare PTGX vs VRTX, REGN, ALNY, ARGX, INSM

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PTGX icon
PTGX
Protagonist Therapeutics Inc
103.70 6.66B 46.02M -130.15M 56.08M -2.0427
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
452.50 115.58B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
752.21 79.23B 14.34B 4.50B 3.77B 41.56
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
328.13 43.59B 3.71B 313.75M 465.38M 2.2571
ARGX icon
ARGX
Argen X Se Adr
692.41 43.26B 4.16B 1.29B 734.26M 19.58
INSM icon
INSM
Insmed Inc
147.84 31.97B 606.42M -1.28B -997.58M -6.403

Protagonist Therapeutics Inc Stock (PTGX) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-17-25 Initiated Barclays Overweight
Sep-12-25 Initiated Leerink Partners Outperform
Jun-17-25 Initiated Citigroup Buy
Dec-06-24 Initiated BMO Capital Markets Outperform
Dec-06-24 Initiated Goldman Neutral
Nov-05-24 Initiated Wedbush Outperform
Sep-24-24 Initiated TD Cowen Buy
Sep-09-24 Initiated Truist Buy
Oct-30-23 Initiated CapitalOne Overweight
May-25-23 Resumed Jefferies Buy
Aug-25-22 Initiated JMP Securities Mkt Outperform
Feb-11-22 Initiated BTIG Research Buy
Oct-12-21 Upgrade JP Morgan Neutral → Overweight
Oct-11-21 Upgrade Northland Capital Market Perform → Outperform
Sep-20-21 Downgrade JP Morgan Overweight → Neutral
May-24-21 Initiated JMP Securities Mkt Outperform
May-24-21 Initiated Northland Capital Outperform
Jan-06-21 Initiated JP Morgan Overweight
Dec-16-20 Initiated Piper Sandler Overweight
Sep-18-20 Reiterated H.C. Wainwright Buy
Jul-15-20 Initiated Jefferies Buy
May-18-20 Reiterated H.C. Wainwright Buy
Jul-08-19 Initiated H.C. Wainwright Buy
May-09-19 Upgrade Stifel Hold → Buy
Dec-06-18 Initiated Nomura Buy
Jan-29-18 Initiated Stifel Buy
Jul-21-17 Initiated BTIG Research Buy
View All

Protagonist Therapeutics Inc Stock (PTGX) Latest News

pulisher
05:17 AM

JPMorgan Chase & Co. Decreases Stake in Protagonist Therapeutics, Inc. $PTGX - MarketBeat

05:17 AM
pulisher
Mar 25, 2026

Aug Chart Watch: Can Protagonist Therapeutics Inc be the next market leader2026 Review & AI Enhanced Execution Alerts - baoquankhu1.vn

Mar 25, 2026
pulisher
Mar 25, 2026

Dinesh Ph Patel Sells 54,641 Shares of Protagonist Therapeutics (NASDAQ:PTGX) Stock - MarketBeat

Mar 25, 2026
pulisher
Mar 25, 2026

Protagonist Therapeutics(PTGX.US) Officer Sells US$5.52 Million in Common Stock - Moomoo

Mar 25, 2026
pulisher
Mar 25, 2026

Jefferies, Johnson Rice Maintain Buy on Protagonist Therapeutics (PTGX) March 2026 - Meyka

Mar 25, 2026
pulisher
Mar 25, 2026

US High Growth Tech Stocks to Watch Now - simplywall.st

Mar 25, 2026
pulisher
Mar 25, 2026

Highs Report: Is Protagonist Therapeutics Inc forming a bullish divergenceWeekly Stock Report & Intraday High Probability Setup Alerts - baoquankhu1.vn

Mar 25, 2026
pulisher
Mar 24, 2026

PTGX (NASDAQ: PTGX) option exercise sale of 54,700 shares - Stock Titan

Mar 24, 2026
pulisher
Mar 24, 2026

Protagonist Partners With Johnson & Johnson To Compete With AbbVie's Skyrizi - Seeking Alpha

Mar 24, 2026
pulisher
Mar 23, 2026

H.C. Wainwright Maintains Protagonist Therapeutics(PTGX.US) With Buy Rating, Maintains Target Price $117 - Moomoo

Mar 23, 2026
pulisher
Mar 22, 2026

Protagonist Therapeutics stock rallies nearly 7% in a week: Here's why - MSN

Mar 22, 2026
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Mar 22, 2026

Wall Street Says Johnson And Johnson’s FDA-Approved Psoriasis Drug Should Create 'Significant Value’ For Protagonist Therapeutics - Stocktwits

Mar 22, 2026
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Mar 22, 2026

Wall Street says Johnson and Johnson’s FDA-approved psoriasis drug should create 'significant value' for Protagonist Therapeutics - MSN

Mar 22, 2026
pulisher
Mar 21, 2026

Protagonist Therapeutics Soars as FDA Approves ICOTYDE for Plaque Psoriasis, Triggers $50M Milestone - MarketBeat

Mar 21, 2026
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Mar 21, 2026

Protagonist Therapeutics (PTGX) soars 4.7%: Is further upside left in the stock? - MSN

Mar 21, 2026
pulisher
Mar 20, 2026

(PTGX) and the Role of Price-Sensitive Allocations - Stock Traders Daily

Mar 20, 2026
pulisher
Mar 20, 2026

Protagonist Therapeutics wins FDA approval for ICOTYDE and joins Fast 500 ranking - Traders Union

Mar 20, 2026
pulisher
Mar 20, 2026

Protagonist Therapeutics Stock Rallies Nearly 7% in a Week: Here's Why - Yahoo Finance

Mar 20, 2026
pulisher
Mar 20, 2026

Protagonist Therapeutics (PTGX) Jumps 4.7%: Does the Stock Have More Room to Grow? - Bitget

Mar 20, 2026
pulisher
Mar 20, 2026

A Look At Protagonist Therapeutics (PTGX) Valuation After FDA Approval Of ICOTYDE - Yahoo Finance

Mar 20, 2026
pulisher
Mar 20, 2026

Protagonist Therapeutics (PTGX) Soars 4.7%: Is Further Upside Left in the Stock? - Yahoo Finance

Mar 20, 2026
pulisher
Mar 20, 2026

PTGX Stock Price, Quote & Chart | PROTAGONIST THERAPEUTICS INC (NASDAQ:PTGX) - ChartMill

Mar 20, 2026
pulisher
Mar 20, 2026

Why Protagonist Therapeutics (PTGX) Is Up 6.6% After First Psoriasis Drug Wins FDA Approval And What's Next - Yahoo Finance

Mar 20, 2026
pulisher
Mar 19, 2026

Citigroup Raises Price Target for PTGX to $125, Maintains Buy Ra - GuruFocus

Mar 19, 2026
pulisher
Mar 19, 2026

A Look At Protagonist Therapeutics (PTGX) Valuation After ICOTYDE Receives U.S. FDA Approval - simplywall.st

Mar 19, 2026
pulisher
Mar 19, 2026

PTGX Analyst Rating Update: Leerink Partners Raises Price Target to $110 | PTGX Stock News - GuruFocus

Mar 19, 2026
pulisher
Mar 19, 2026

Protagonist Therapeutics Inc buy JPMorgan Chase & Co. - sharewise.com

Mar 19, 2026
pulisher
Mar 19, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Stock Price Expected to Rise, Leerink Partners Analyst Says - MarketBeat

Mar 19, 2026
pulisher
Mar 19, 2026

Protagonist Therapeutics (PTGX) Receives Rating Update from JP M - GuruFocus

Mar 19, 2026
pulisher
Mar 19, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Given New $106.00 Price Target at JPMorgan Chase & Co. - MarketBeat

Mar 19, 2026
pulisher
Mar 19, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Stock Price Up 4.6% Following Analyst Upgrade - MarketBeat

Mar 19, 2026
pulisher
Mar 19, 2026

Protagonist Therapeutics2026 Funding Rounds & List of Investors - Tracxn

Mar 19, 2026
pulisher
Mar 19, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Price Target Raised to $125.00 at Citigroup - MarketBeat

Mar 19, 2026
pulisher
Mar 19, 2026

Johnson & Johnson-Protagonist Therapeutics partnered new psoriasis pill wins FDA nod, shakes up competition with AbbVie - MSN

Mar 19, 2026
pulisher
Mar 19, 2026

Protagonist Therapeutics (PTGX) Sees Target Price Upgrade from B - GuruFocus

Mar 19, 2026
pulisher
Mar 19, 2026

Protagonist Therapeutics (NASDAQ:PTGX) Given New $119.00 Price Target at Barclays - MarketBeat

Mar 19, 2026
pulisher
Mar 19, 2026

Johnson & Johnson-Protagonist Therapeutics Partnered New Psoriasis Pill Wins FDA Nod, Shakes Up Competition With AbbVie - Benzinga

Mar 19, 2026
pulisher
Mar 19, 2026

Johnson & Johnson-Protagonist Therapeutics Partnered New Psoriasis Pill Wins FDA Nod, Shakes Up Competition With AbbVie - Benzinga

Mar 19, 2026
pulisher
Mar 18, 2026

Clear Street raises Protagonist Therapeutics price target on FDA approval By Investing.com - Investing.com Canada

Mar 18, 2026
pulisher
Mar 18, 2026

Icotyde’s in; wave of switchers to oral psoriasis Protagonist? - BioWorld MedTech

Mar 18, 2026
pulisher
Mar 18, 2026

How an East Bay company picked up $50 million with another $580 million potentially on the way - The Business Journals

Mar 18, 2026
pulisher
Mar 18, 2026

Jefferies, Johnson Rice Maintain Buy on Protagonist Therapeutics (PTGX) Mar 2026 - Meyka

Mar 18, 2026
pulisher
Mar 18, 2026

Barclays raises Protagonist Therapeutics stock price target on FDA approval By Investing.com - Investing.com Australia

Mar 18, 2026
pulisher
Mar 18, 2026

CEO Moves: Is Protagonist Therapeutics Inc stock good for income investorsQuarterly Risk Review & Consistent Profit Focused Trading Strategies - baoquankhu1.vn

Mar 18, 2026
pulisher
Mar 18, 2026

Barclays raises Protagonist Therapeutics stock price target on FDA approval - Investing.com

Mar 18, 2026
pulisher
Mar 18, 2026

Jefferies raises Protagonist Therapeutics price target on drug approval By Investing.com - Investing.com India

Mar 18, 2026
pulisher
Mar 18, 2026

Jefferies raises Protagonist Therapeutics price target on drug approval - Investing.com

Mar 18, 2026
pulisher
Mar 18, 2026

Protagonist Therapeutics, Inc. (PTGX) Discusses FDA Approval of ICOTYDE for Moderate to Severe Plaque Psoriasis TreatmentSlideshow (NASDAQ:PTGX) 2026-03-18 - Seeking Alpha

Mar 18, 2026
pulisher
Mar 18, 2026

Protagonist Therapeutics stock gets Truist buy rating reiterated By Investing.com - Investing.com Canada

Mar 18, 2026
pulisher
Mar 18, 2026

FDA clears Protagonist Therapeutics ICOTYDE as first-line oral plaque psoriasis treatment - Traders Union

Mar 18, 2026
pulisher
Mar 18, 2026

J&J wins FDA nod for plaque psoriasis pill developed with Protagonist - Seeking Alpha

Mar 18, 2026

Protagonist Therapeutics Inc Stock (PTGX) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Protagonist Therapeutics Inc Stock (PTGX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
PATEL DINESH V PH D
President and CEO
Mar 24 '26
Option Exercise
8.58
59
506
524,997
PATEL DINESH V PH D
President and CEO
Mar 25 '26
Sale
101.00
54,641
5,518,741
524,938
PATEL DINESH V PH D
President and CEO
Mar 24 '26
Sale
101.00
59
5,959
524,938
$27.09
price down icon 1.13%
$47.08
price up icon 3.03%
$52.88
price up icon 3.11%
$87.70
price down icon 0.90%
ONC ONC
$272.99
price down icon 1.11%
$147.84
price up icon 6.51%
Cap:     |  Volume (24h):