loading
Protagonist Therapeutics Inc stock is traded at $131.42, with a volume of 954.57K. It is down -4.52% in the last 24 hours and up +24.25% over the past month. Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
See More
Previous Close:
$137.64
Open:
$137.12
24h Volume:
954.57K
Relative Volume:
1.34
Market Cap:
$8.45B
Revenue:
$74.06M
Net Income/Loss:
$-114.71M
P/E Ratio:
-72.85
EPS:
-1.8039
Net Cash Flow:
$-117.90M
1W Performance:
-0.15%
1M Performance:
+24.25%
6M Performance:
+63.82%
1Y Performance:
+148.78%
1-Day Range:
Value
$130.64
$137.12
1-Week Range:
Value
$128.15
$141.10
52-Week Range:
Value
$50.48
$141.10

Protagonist Therapeutics Inc Stock (PTGX) Company Profile

Name
Name
Protagonist Therapeutics Inc
Name
Phone
(510) 474-0170
Name
Address
7707 GATEWAY BLVD., SUITE 140, NEWARK, CA
Name
Employee
131
Name
Twitter
Name
Next Earnings Date
2026-08-05
Name
Latest SEC Filings
Name
PTGX's Discussions on Twitter

Compare PTGX vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PTGX icon
PTGX
Protagonist Therapeutics Inc
131.42 8.45B 74.06M -114.71M -117.90M -1.8039
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
485.39 123.19B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
664.52 69.67B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
877.62 54.58B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
298.76 39.89B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
186.88 39.73B 742.00K -1.37B -1.07B -7.0731

Protagonist Therapeutics Inc Stock (PTGX) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-17-25 Initiated Barclays Overweight
Sep-12-25 Initiated Leerink Partners Outperform
Jun-17-25 Initiated Citigroup Buy
Dec-06-24 Initiated BMO Capital Markets Outperform
Dec-06-24 Initiated Goldman Neutral
Nov-05-24 Initiated Wedbush Outperform
Sep-24-24 Initiated TD Cowen Buy
Sep-09-24 Initiated Truist Buy
Oct-30-23 Initiated CapitalOne Overweight
May-25-23 Resumed Jefferies Buy
Aug-25-22 Initiated JMP Securities Mkt Outperform
Feb-11-22 Initiated BTIG Research Buy
Oct-12-21 Upgrade JP Morgan Neutral → Overweight
Oct-11-21 Upgrade Northland Capital Market Perform → Outperform
Sep-20-21 Downgrade JP Morgan Overweight → Neutral
May-24-21 Initiated JMP Securities Mkt Outperform
May-24-21 Initiated Northland Capital Outperform
Jan-06-21 Initiated JP Morgan Overweight
Dec-16-20 Initiated Piper Sandler Overweight
Sep-18-20 Reiterated H.C. Wainwright Buy
Jul-15-20 Initiated Jefferies Buy
May-18-20 Reiterated H.C. Wainwright Buy
Jul-08-19 Initiated H.C. Wainwright Buy
May-09-19 Upgrade Stifel Hold → Buy
Dec-06-18 Initiated Nomura Buy
Jan-29-18 Initiated Stifel Buy
Jul-21-17 Initiated BTIG Research Buy
View All

Protagonist Therapeutics Inc Stock (PTGX) Latest News

pulisher
Jul 11, 2026

Protagonist Therapeutics (PTGX) Goldman Sachs 47th Annual Global Healthcare Conference 2026 summary - Quartr

Jul 11, 2026
pulisher
Jul 11, 2026

Protagonist Therapeutics (PTGX) AGM 2026 Summary - Quartr

Jul 11, 2026
pulisher
Jul 11, 2026

Protagonist Therapeutics (PTGX) Investor Update Summary - Quartr

Jul 11, 2026
pulisher
Jul 09, 2026

Protagonist Therapeutics (PTGX) Stock Still Looks Stretched After FDA Priority Review - Yahoo Finance

Jul 09, 2026
pulisher
Jul 09, 2026

Protagonist Therapeutics (PTGX) After Icotyde Launch And Rusfertide Review Looks Undervalued - Yahoo Finance

Jul 09, 2026
pulisher
Jul 09, 2026

Liquidity Mapping Around (PTGX) Price Events - Stock Traders Daily

Jul 09, 2026
pulisher
Jul 09, 2026

New Strong Buy Stocks for July 9th - Yahoo Finance

Jul 09, 2026
pulisher
Jul 08, 2026

Protagonist Therapeutics (PTGX) Could Be 66% Below Fair Value As Pipeline Progress Lifts Interest - simplywall.st

Jul 08, 2026
pulisher
Jul 08, 2026

Protagonist Therapeutics (PTGX) Is Up 12.5% After Rusfertide Priority Review FocusHas The Bull Case Changed? - Yahoo Finance

Jul 08, 2026
pulisher
Jul 08, 2026

Protagonist Therapeutics (PTGX) Surges 7.1%: Is This an Indication of Further Gains? - Yahoo Finance

Jul 08, 2026
pulisher
Jul 08, 2026

Strength Seen in Agios Pharmaceuticals (AGIO): Can Its 17.7% Jump Turn into More Strength? - Yahoo Finance

Jul 08, 2026
pulisher
Jul 08, 2026

Protagonist Therapeutics (PTGX) TD Cowen 46th Annual Health Care Conference Summary - Quartr

Jul 08, 2026
pulisher
Jul 07, 2026

PTGX climbs as target hike adds to late-stage pipeline optimism - Quiver Quantitative

Jul 07, 2026
pulisher
Jul 07, 2026

PTGX Stock Grinds Higher As Pipeline Catalysts Build - StocksToTrade

Jul 07, 2026
pulisher
Jul 07, 2026

Truist raises Protagonist Therapeutics stock price target on Icotyde outlook By Investing.com - Investing.com India

Jul 07, 2026
pulisher
Jul 07, 2026

Protagonist Therapeutics updates its clinical pipeline. PTGX focuses on peptide-based therapies - ad-hoc-news.de

Jul 07, 2026
pulisher
Jul 07, 2026

Protagonist Therapeutics Jumps 5.2% Amid Sector-Wide Rally - AlphaStreet

Jul 07, 2026
pulisher
Jul 07, 2026

PTGX Stock Surges 64% in Six Months: What Is Driving the Rally? - TradingView

Jul 07, 2026
pulisher
Jul 07, 2026

Truist Financial Maintains Protagonist Therapeutics(PTGX.US) With Buy Rating, Announces Target Price $145 - Moomoo

Jul 07, 2026
pulisher
Jul 07, 2026

PTGX Maintained by Truist Securities -- Price Target Raised to $145.00 - GuruFocus

Jul 07, 2026
pulisher
Jul 07, 2026

Truist raises Protagonist Therapeutics stock price target on Icotyde outlook - Investing.com

Jul 07, 2026
pulisher
Jul 07, 2026

Price to sales forward of Protagonist Therapeutics, Inc. – NASDAQ:PTGX - TradingView

Jul 07, 2026
pulisher
Jul 07, 2026

Truist Raises Price Target on Protagonist Therapeutics to $145 From $121, Keeps Buy Rating - Moomoo

Jul 07, 2026
pulisher
Jul 06, 2026

Protagonist Therapeutics Inc stock hits all-time high at 131.99 USD - Investing.com

Jul 06, 2026
pulisher
Jul 04, 2026

PTGXProtagonist Therapeutics Inc Volatility & Greeks - Finviz

Jul 04, 2026
pulisher
Jul 03, 2026

Protagonist Therapeutics updates its pipeline. PTGX focuses on peptide drug development - ad-hoc-news.de

Jul 03, 2026
pulisher
Jul 02, 2026

Why Wall Street’s Wrong for Loving Protagonist Therapeutics Stock - Yahoo Finance

Jul 02, 2026
pulisher
Jul 01, 2026

Protagonist Therapeutics Reports Granting of Inducement Awards - ACCESS Newswire

Jul 01, 2026
pulisher
Jul 01, 2026

Protagonist Therapeutics awards new hires stock options and RSUs - Stock Titan

Jul 01, 2026
pulisher
Jul 01, 2026

Protagonist Therapeutics stock rating reiterated at Buy by TD Cowen - Investing.com South Africa

Jul 01, 2026
pulisher
Jun 28, 2026

Why (PTGX) Price Action Is Critical for Tactical Trading - Stock Traders Daily

Jun 28, 2026
pulisher
Jun 26, 2026

Wall Street Says Johnson And Johnson’s FDA-Approved Psoriasis Drug Should Create 'Significant Value’ For Protagonist Therapeutics - Stocktwits

Jun 26, 2026
pulisher
Jun 26, 2026

Protagonist Therapeutics Inc (PTGX) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Jun 26, 2026
pulisher
Jun 25, 2026

Form 4 Protagonist Therapeutics Inc For: 25 June By Investing.com - Investing.com Nigeria

Jun 25, 2026
pulisher
Jun 25, 2026

Protagonist Therapeutics, Inc. Actuals & Estimates (NASDAQ:PTGX) - TradingView

Jun 25, 2026
pulisher
Jun 25, 2026

Protagonist Therapeutics director Waddill sells $1.06m in stock By Investing.com - Investing.com Nigeria

Jun 25, 2026
pulisher
Jun 25, 2026

Protagonist Therapeutics director Waddill sells $1.06m in stock - Investing.com

Jun 25, 2026
pulisher
Jun 25, 2026

Director at Protagonist (NASDAQ: PTGX) trades 9,000 shares under 10b5-1 plan - Stock Titan

Jun 25, 2026
pulisher
Jun 25, 2026

Protagonist Therapeutics stock hits all-time high at 124.97 USD By Investing.com - Investing.com South Africa

Jun 25, 2026
pulisher
Jun 25, 2026

PTGX Forecast — Price Target — Prediction for 2027 - TradingView

Jun 25, 2026
pulisher
Jun 25, 2026

Protagonist Therapeutics stock hits all-time high at 124.97 USD - Investing.com

Jun 25, 2026
pulisher
Jun 25, 2026

Protagonist Therapeutics, Inc. Stock 12‑Month Price Target Raised to $119.15, Implies 2% Downside - TradingView

Jun 25, 2026
pulisher
Jun 24, 2026

Why Is Silence Therapeutics Stock Soaring Wednesday?Silence Therapeutics (NASDAQ:SLN) - Benzinga

Jun 24, 2026
pulisher
Jun 24, 2026

The Bull Case For Protagonist Therapeutics (PTGX) Could Change Following Surging Institutional Buying Interest - Sahm

Jun 24, 2026
pulisher
Jun 23, 2026

Form 144 PROTAGONIST THERAPEUTICS For: 23 June By Investing.com - Investing.com Nigeria

Jun 23, 2026
pulisher
Jun 23, 2026

PTGX (NASDAQ) Form 144: Director-linked 9,000-share sales and option exercise - Stock Titan

Jun 23, 2026

Protagonist Therapeutics Inc Stock (PTGX) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading

Protagonist Therapeutics Inc Stock (PTGX) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Waddill William D.
Director
Jun 23 '26
Sale
117.94
9,000
1,061,460
7,825
$56.43
price down icon 2.64%
$115.61
price down icon 2.24%
$35.97
price down icon 2.28%
$68.27
price down icon 10.83%
ONC ONC
$298.70
price down icon 1.36%
$186.88
price down icon 2.22%
Cap:     |  Volume (24h):