9.36
price down icon0.43%   -0.04
pre-market  Pre-market:  9.45   0.09   +0.96%
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Prothena Corporation Plc stock is traded at $9.36, with a volume of 553.44K. It is down -0.43% in the last 24 hours and up +6.61% over the past month. Prothena Corp PLC is a clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. The company's clinical pipeline of antibody-based product candidates targets a range of indications, including Amyloid Light-chain (AL) amyloidosis (NEOD001), Parkinson's disease and other related synucleinopathies (PRX002), and inflammatory diseases, including ATTR amyloidosis [Coramitug (PRX004)], Alzheimer's disease (PRX123), Neurodegeneration (PRXPRX019), and Others.
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Previous Close:
$9.40
Open:
$9.09
24h Volume:
553.44K
Relative Volume:
0.99
Market Cap:
$503.85M
Revenue:
$217.25M
Net Income/Loss:
$-50.92M
P/E Ratio:
-9.36
EPS:
-1
Net Cash Flow:
$-100.85M
1W Performance:
+4.35%
1M Performance:
+6.61%
6M Performance:
+11.56%
1Y Performance:
-34.68%
1-Day Range:
Value
$8.95
$9.615
1-Week Range:
Value
$8.48
$9.615
52-Week Range:
Value
$4.32
$15.63

Prothena Corporation Plc Stock (PRTA) Company Profile

Name
Name
Prothena Corporation Plc
Name
Phone
011-353-1-236-2500
Name
Address
77 SIR JOHN ROGERSON'S QUAY, BLOCK C, DUBLIN 2
Name
Employee
163
Name
Twitter
@ProthenaCorp
Name
Next Earnings Date
2025-02-18
Name
Latest SEC Filings
Name
PRTA's Discussions on Twitter

Compare PRTA vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
PRTA
Prothena Corporation Plc
9.36 506.00M 217.25M -50.92M -100.85M -1.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
474.27 123.47B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
766.66 83.60B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
748.72 46.83B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
318.65 43.11B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
297.04 34.79B 5.36B 287.73M 924.18M 2.5229

Prothena Corporation Plc Stock (PRTA) Upgrades & Downgrades

Date Action Analyst Rating Change
May-28-25 Downgrade BofA Securities Neutral → Underperform
May-27-25 Downgrade Cantor Fitzgerald Overweight → Neutral
May-27-25 Downgrade Jefferies Buy → Hold
May-27-25 Downgrade Oppenheimer Outperform → Perform
Dec-20-24 Initiated Chardan Capital Markets Buy
Jan-30-24 Downgrade BofA Securities Buy → Neutral
Dec-12-23 Initiated Deutsche Bank Buy
Apr-24-23 Initiated SVB Securities Outperform
Jan-27-23 Initiated Piper Sandler Overweight
Nov-04-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-28-22 Upgrade BofA Securities Neutral → Buy
Nov-19-21 Initiated JMP Securities Mkt Outperform
Jun-18-21 Upgrade BofA Securities Underperform → Neutral
Jun-08-21 Reiterated Oppenheimer Outperform
May-26-21 Initiated Citigroup Buy
Feb-26-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-12-21 Upgrade Jefferies Hold → Buy
Feb-02-21 Upgrade BTIG Research Neutral → Buy
Dec-07-20 Initiated H.C. Wainwright Buy
Jul-09-20 Upgrade Oppenheimer Perform → Outperform
Nov-19-19 Upgrade Evercore ISI In-line → Outperform
May-21-18 Downgrade Barclays Equal Weight → Underweight
Apr-23-18 Downgrade Jefferies Buy → Hold
Apr-05-18 Reiterated Barclays Overweight
Nov-20-17 Downgrade Wedbush Outperform → Neutral
Sep-29-17 Reiterated BTIG Research Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-17-17 Initiated Evercore ISI Outperform
Jul-11-17 Initiated Jefferies Buy
Apr-12-17 Initiated Cantor Fitzgerald Overweight
Apr-12-17 Initiated Piper Jaffray Overweight
Mar-02-17 Initiated Instinet Buy
Dec-21-16 Initiated SunTrust Buy
Nov-03-16 Initiated Deutsche Bank Buy
Aug-04-16 Reiterated Barclays Overweight
May-13-16 Initiated Barclays Overweight
Feb-19-16 Reiterated Wedbush Outperform
Jan-21-16 Initiated Credit Suisse Outperform
View All

Prothena Corporation Plc Stock (PRTA) Latest News

pulisher
Mar 03, 2026

Wall Street Analysts Believe Prothena (PRTA) Could Rally 118.09%: Here's is How to Trade - Zacks Investment Research

Mar 03, 2026
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Mar 02, 2026

Prothena (NASDAQ:PRTA) Shares Up 8.7%Still a Buy? - MarketBeat

Mar 02, 2026
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Mar 02, 2026

Prothena Corporation plc (NASDAQ:PRTA) Given Average Recommendation of “Hold” by Analysts - Defense World

Mar 02, 2026
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Mar 01, 2026

PRTA SEC FilingsProthena 10-K, 10-Q, 8-K Forms - Stock Titan

Mar 01, 2026
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Feb 27, 2026

Prothena Corporation plc (PRTA) Stock Analysis: Navigating a 137% Potential Upside in the Biotech Sector - DirectorsTalk Interviews

Feb 27, 2026
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Feb 27, 2026

Prothena Announces $100 Million Share Repurchase Program - TipRanks

Feb 27, 2026
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Feb 27, 2026

Prothena authorizes $100 million share buyback program - Investing.com

Feb 27, 2026
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Feb 27, 2026

Prothena Corporation plc announces an Equity Buyback for $100 million worth of its shares. - marketscreener.com

Feb 27, 2026
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Feb 27, 2026

Prothena (NASDAQ: PRTA) okays $100M share buyback through 2026 - Stock Titan

Feb 27, 2026
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Feb 27, 2026

Prothena Approves $100 Million Share Buyback Authorization - marketscreener.com

Feb 27, 2026
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Feb 27, 2026

Prothena stock jumps on $100M share buyback authorization - Investing.com UK

Feb 27, 2026
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Feb 27, 2026

Prothena Corporation plc (NASDAQ: PRTA) clears shelf to sell up to $200M in shares - Stock Titan

Feb 27, 2026
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Feb 27, 2026

Prothena Announces up to $100 Million Share Repurchase Plan - Bluefield Daily Telegraph

Feb 27, 2026
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Feb 27, 2026

PROTHENA CORP PUBLIC LTD CO SEC 10-K Report - TradingView

Feb 27, 2026
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Feb 26, 2026

Prothena Corporation plc authorizes a Buyback Plan. - marketscreener.com

Feb 26, 2026
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Feb 26, 2026

Behavioral Patterns of PRTA and Institutional Flows - Stock Traders Daily

Feb 26, 2026
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Feb 23, 2026

FY2026 EPS Estimates for Prothena Boosted by HC Wainwright - MarketBeat

Feb 23, 2026
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Feb 22, 2026

Royal Bank Of Canada Increases Prothena (NASDAQ:PRTA) Price Target to $12.00 - Defense World

Feb 22, 2026
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Feb 20, 2026

RBC Capital Raises Price Target for Prothena Corp (PRTA) to $12. - GuruFocus

Feb 20, 2026
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Feb 20, 2026

Prothena Q4 Earnings Meet Estimates, Pipeline Progress in Focus - Finviz

Feb 20, 2026
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Feb 20, 2026

Prothena (NASDAQ:PRTA) Price Target Raised to $12.00 - MarketBeat

Feb 20, 2026
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Feb 20, 2026

Prothena Corporation plc (NASDAQ:PRTA) Q4 2025 Earnings Call Transcript - Insider Monkey

Feb 20, 2026
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Feb 20, 2026

Prothena Corporation plc Q4 2025 Earnings Call Summary - Yahoo Finance

Feb 20, 2026
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Feb 20, 2026

Prothena Corp PLC (PRTA) Q4 2025 Earnings Call Highlights: Strat - GuruFocus

Feb 20, 2026
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Feb 19, 2026

Prothena Q4 Earnings Call Highlights - MarketBeat

Feb 19, 2026
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Feb 19, 2026

Can Prothena Corporation plc be recession proofTrade Exit Summary & Growth Focused Stock Reports - mfd.ru

Feb 19, 2026
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Feb 19, 2026

Prothena (PRTA) Reports Q4 Loss, Lags Revenue Estimates - Yahoo Finance

Feb 19, 2026
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Feb 19, 2026

Prothena (PRTA) Projects Financial Outlook and Clinical Milestones - GuruFocus

Feb 19, 2026
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Feb 19, 2026

Prothena Corporation plc announced that the company has the potential to receive up to $105 million in cumulative clinical milestone payments by the end of 2026. - Bitget

Feb 19, 2026
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Feb 19, 2026

Prothena (NASDAQ:PRTA) Releases Earnings Results, Beats Estimates By $0.01 EPS - MarketBeat

Feb 19, 2026
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Feb 19, 2026

Prothena Reports Fourth Quarter and Full Year 2025 Financial Results, and Provides Financial Guidance and Business Highlights - The Joplin Globe

Feb 19, 2026
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Feb 18, 2026

Exploring Prothena Corp's Earnings Expectations - Benzinga

Feb 18, 2026
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Feb 16, 2026

Prothena Stock Tumbles 36.8% Year Over Year: What Lies Ahead? - Finviz

Feb 16, 2026
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Feb 15, 2026

(PRTA) Movement Within Algorithmic Entry Frameworks - Stock Traders Daily

Feb 15, 2026
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Feb 15, 2026

Will Prothena Corporation plc stock remain a Wall Street favoriteQuarterly Portfolio Review & AI Optimized Trading Strategy Guides - mfd.ru

Feb 15, 2026
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Feb 13, 2026

Prothena Corporation plc (PRTA) Stock Analysis: Exploring a 129.76% Potential Upside in Biotechnology - DirectorsTalk Interviews

Feb 13, 2026
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Feb 12, 2026

Prothena to Report Fourth Quarter and Full Year 2025 Financial Results on February 19, 2026 - pharmiweb.com

Feb 12, 2026
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Feb 12, 2026

Prothena (PRTA) Projected to Post Quarterly Earnings on Thursday - MarketBeat

Feb 12, 2026
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Feb 11, 2026

Is Prothena Corporation plc stock affected by interest rate hikes2025 Retail Activity & Short-Term Trading Opportunity Alerts - mfd.ru

Feb 11, 2026
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Feb 11, 2026

Will Prothena Corporation plc benefit from rising consumer demandJuly 2025 Retail & Stepwise Swing Trade Plans - mfd.ru

Feb 11, 2026
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Feb 10, 2026

Aug Levels: Will Prothena Corporation plc benefit from rising consumer demandMarket Performance Recap & High Accuracy Trade Alerts - baoquankhu1.vn

Feb 10, 2026
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Feb 09, 2026

Volatility Watch: How do insiders feel about Prothena Corporation plcWeekly Stock Report & Smart Money Movement Tracker - baoquankhu1.vn

Feb 09, 2026
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Feb 05, 2026

Prothena Corporation plc (NASDAQ:PRTA) Given Average Rating of "Hold" by Analysts - MarketBeat

Feb 05, 2026
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Feb 04, 2026

How (PRTA) Movements Inform Risk Allocation Models - Stock Traders Daily

Feb 04, 2026
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Feb 03, 2026

Prothena Corporation plc $PRTA Shares Sold by Federated Hermes Inc. - MarketBeat

Feb 03, 2026
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Jan 31, 2026

Prothena Corporation plc (PRTA) Stock Analysis: Exploring a Potential 124% Upside in Biotech Innovations - DirectorsTalk Interviews

Jan 31, 2026
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Jan 27, 2026

Prothena (NASDAQ:PRTA) Share Price Crosses Above 50 Day Moving AverageHere's Why - MarketBeat

Jan 27, 2026
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Jan 24, 2026

Can Calidi Biotherapeutics Inc reach resistance levels soonWeekly Stock Summary & Community Trade Idea Sharing - baoquankhu1.vn

Jan 24, 2026
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Jan 24, 2026

Trading Systems Reacting to (PRTA) Volatility - Stock Traders Daily

Jan 24, 2026
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Jan 23, 2026

Prothena Corporation Plc (PRTA) Stock Analysis: Evaluating A Potential 96.65% Upside - DirectorsTalk Interviews

Jan 23, 2026
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Jan 21, 2026

All You Need to Know About Prothena (PRTA) Rating Upgrade to Buy - Yahoo Finance

Jan 21, 2026

Prothena Corporation Plc Stock (PRTA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$49.83
price down icon 5.71%
$27.85
price down icon 0.89%
$47.48
price up icon 0.02%
$100.76
price down icon 6.25%
$147.00
price up icon 0.46%
biotechnology ONC
$297.04
price down icon 5.51%
Cap:     |  Volume (24h):