8.35
price down icon1.76%   -0.15
 
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Prothena Corp Plc stock is traded at $8.35, with a volume of 670.25K. It is down -1.76% in the last 24 hours and up +1.33% over the past month. Prothena Corp PLC is a late-stage clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. Prothena is developing and applying its proprietary CYTOPE technology to target a broad spectrum of intracellular disease pathways in the brain and periphery. The company's pipeline includes both wholly-owned and partnered programs like Prasinezumab, Coramitug (PRX004), BMS-986446 (PRX005), PRX019, TDP-43 CYTOPE, and PRX012-TfR, being developed for the potential treatment of Parkinson's disease, ATTR amyloidosis with cardiomyopathy, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), and other neurodegenerative diseases.
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Previous Close:
$8.50
Open:
$8.58
24h Volume:
670.25K
Relative Volume:
1.08
Market Cap:
$428.66M
Revenue:
$57.94M
Net Income/Loss:
$-151.18M
P/E Ratio:
-2.9698
EPS:
-2.8116
Net Cash Flow:
$-86.56M
1W Performance:
-5.54%
1M Performance:
+1.33%
6M Performance:
-20.63%
1Y Performance:
-17.24%
1-Day Range:
Value
$8.24
$8.62
1-Week Range:
Value
$8.19
$8.81
52-Week Range:
Value
$7.73
$11.80

Prothena Corp Plc Stock (PRTA) Company Profile

Name
Name
Prothena Corp Plc
Name
Phone
011-353-1-236-2500
Name
Address
77 SIR JOHN ROGERSON'S QUAY, BLOCK C, DUBLIN 2
Name
Employee
67
Name
Twitter
@ProthenaCorp
Name
Next Earnings Date
2026-11-05
Name
Latest SEC Filings
Name
PRTA's Discussions on Twitter

Compare PRTA vs VRTX, MRNA, REGN, ARGX, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRTA icon
PRTA
Prothena Corp Plc
8.35 428.66M 57.94M -151.18M -86.56M -2.8116
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
499.74 126.66B 12.34B 4.34B 3.71B 16.87
MRNA icon
MRNA
Moderna Inc
218.01 87.04B 2.23B -3.19B -1.60B -8.1462
REGN icon
REGN
Regeneron Pharmaceuticals Inc
790.74 81.41B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
819.14 51.51B 4.16B 1.29B 734.26M 19.58
ONC icon
ONC
Beone Medicines Ltd Adr
369.06 41.75B 5.76B 514.49M 1.10B 4.4813

Prothena Corp Plc Stock (PRTA) Upgrades & Downgrades

Date Action Analyst Rating Change
May-28-25 Downgrade BofA Securities Neutral → Underperform
May-27-25 Downgrade Cantor Fitzgerald Overweight → Neutral
May-27-25 Downgrade Jefferies Buy → Hold
May-27-25 Downgrade Oppenheimer Outperform → Perform
Dec-20-24 Initiated Chardan Capital Markets Buy
Jan-30-24 Downgrade BofA Securities Buy → Neutral
Dec-12-23 Initiated Deutsche Bank Buy
Apr-24-23 Initiated SVB Securities Outperform
Jan-27-23 Initiated Piper Sandler Overweight
Nov-04-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-28-22 Upgrade BofA Securities Neutral → Buy
Nov-19-21 Initiated JMP Securities Mkt Outperform
Jun-18-21 Upgrade BofA Securities Underperform → Neutral
Jun-08-21 Reiterated Oppenheimer Outperform
May-26-21 Initiated Citigroup Buy
Feb-26-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-12-21 Upgrade Jefferies Hold → Buy
Feb-02-21 Upgrade BTIG Research Neutral → Buy
Dec-07-20 Initiated H.C. Wainwright Buy
Jul-09-20 Upgrade Oppenheimer Perform → Outperform
Nov-19-19 Upgrade Evercore ISI In-line → Outperform
May-21-18 Downgrade Barclays Equal Weight → Underweight
Apr-23-18 Downgrade Jefferies Buy → Hold
Apr-05-18 Reiterated Barclays Overweight
Nov-20-17 Downgrade Wedbush Outperform → Neutral
Sep-29-17 Reiterated BTIG Research Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-17-17 Initiated Evercore ISI Outperform
Jul-11-17 Initiated Jefferies Buy
Apr-12-17 Initiated Cantor Fitzgerald Overweight
Apr-12-17 Initiated Piper Jaffray Overweight
Mar-02-17 Initiated Instinet Buy
Dec-21-16 Initiated SunTrust Buy
Nov-03-16 Initiated Deutsche Bank Buy
Aug-04-16 Reiterated Barclays Overweight
May-13-16 Initiated Barclays Overweight
Feb-19-16 Reiterated Wedbush Outperform
Jan-21-16 Initiated Credit Suisse Outperform
View All

Prothena Corp Plc Stock (PRTA) Latest News

pulisher
Oct 11, 2026

Form 4 PROTHENA CORP PUBLIC LTD CO For: 11 October By Investing.com - Investing.com Nigeria

Oct 11, 2026
pulisher
Oct 10, 2026

Form 4 PROTHENA CORP PUBLIC LTD CO For: 10 October By Investing.com - Investing.com Canada

Oct 10, 2026
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Oct 10, 2026

Form 4 PROTHENA CORP PUBLIC LTD CO For: 10 October By Investing.com - Investing.com India

Oct 10, 2026
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Oct 10, 2026

Form 4 PROTHENA CORP PUBLIC LTD CO For: 10 October By Investing.com - Investing.com South Africa

Oct 10, 2026
pulisher
Oct 08, 2026

CRMD vs. PRTA: Which Stock Should Value Investors Buy Now? - Zacks Investment Research

Oct 08, 2026
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Oct 06, 2026

Prothena Director William P. Scully Acquires 100,000 Shares at $8.57 Each - Kalkine Media

Oct 06, 2026
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Oct 06, 2026

Insider Stock Purchases: October 06, 2026 - Quiver Quantitative

Oct 06, 2026
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Oct 02, 2026

A development chief is leaving Prothena (PRTA) to join one of its strategic partners. - stocktitan.net

Oct 02, 2026
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Oct 02, 2026

Prothena Corporation Public Limited Company Announces Resignation of Chad J. Swanson, Ph.D. as Chief Development Officer, Effective October 9, 2026 - marketscreener.com

Oct 02, 2026
pulisher
Oct 01, 2026

Form 4 PROTHENA CORP PUBLIC LTD CO For: 1 October By Investing.com - Investing.com Canada

Oct 01, 2026
pulisher
Sep 29, 2026

Form 4 PROTHENA CORP PUBLIC LTD CO For: 29 September By Investing.com - Investing.com Nigeria

Sep 29, 2026
pulisher
Sep 29, 2026

Form 4 PROTHENA CORP PUBLIC LTD CO For: 29 September By Investing.com - Investing.com Canada

Sep 29, 2026
pulisher
Sep 29, 2026

Form 4 PROTHENA CORP PUBLIC LTD CO For: 29 September By Investing.com - Investing.com UK

Sep 29, 2026
pulisher
Sep 27, 2026

Form 4 PROTHENA CORP PUBLIC LTD CO For: 27 September - Investing.com India

Sep 27, 2026
pulisher
Sep 24, 2026

Insider Stock Purchases: September 24, 2026 - Quiver Quantitative

Sep 24, 2026
pulisher
Sep 21, 2026

Prothena Director William P. Scully Acquires 100,000 Shares at Average Price of $8.43 - kalkinemedia.com

Sep 21, 2026
pulisher
Sep 21, 2026

Prothena Corp Public Ltd Insider Bought Shares Worth $843,460, According to a Recent SEC Filing - Yahoo Finance

Sep 21, 2026
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Sep 09, 2026

Prothena to Participate in the H.C. Wainwright 28th Annual Global Investment Conference - Yahoo Finance

Sep 09, 2026
pulisher
Sep 09, 2026

A biotech company's leaders will speak live in New York Sept. 16 - Stock Titan

Sep 09, 2026
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Sep 05, 2026

Prothena stock holds near USD 9.60 after market cap update - AD HOC NEWS

Sep 05, 2026
pulisher
Sep 03, 2026

Prothena Director William P. Scully Acquires 27,000 Shares in Open Market - kalkinemedia.com

Sep 03, 2026
pulisher
Sep 02, 2026

Responsive Playbooks and the PRTA Inflection - Stock Traders Daily

Sep 02, 2026
pulisher
Sep 01, 2026

Sarissa Capital Management and Alexander J. Denner Hold 25.7 Million Shares in Amarin Corporation (NASDAQ: AMRN) - kalkinemedia.com

Sep 01, 2026
pulisher
Aug 31, 2026

Prothena Corporation plc (PRTA) Key Financial Ratios – Valuation, Profitability & More - Value Research

Aug 31, 2026
pulisher
Aug 28, 2026

Prothena Stock Price Forecast. Should You Buy PRTA? - StockInvest.us

Aug 28, 2026
pulisher
Aug 28, 2026

Prothena Corporation plc (PRTA) Financials – Balance Sheet, Profit & Loss, Cash Flow - Value Research

Aug 28, 2026
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Aug 28, 2026

Prothena Corporation plc (PRTA) Shareholding Pattern – Promoters, FIIs & DIIs - Value Research

Aug 28, 2026
pulisher
Aug 21, 2026

Prothena (NASDAQ:PRTA) Major Shareholder Buys 50,000 Shares of Stock - MarketBeat

Aug 21, 2026
pulisher
Aug 21, 2026

Prothena (NASDAQ: PRTA) insider lifts direct stake to 800,000 shares - stocktitan.net

Aug 21, 2026
pulisher
Aug 19, 2026

Trustee controls a tenth of Prothena (PRTA) stock via trusts - Stock Titan

Aug 19, 2026
pulisher
Aug 19, 2026

Prothena (NASDAQ:PRTA) Shares Pass Below Two Hundred Day Moving AverageShould You Sell? - MarketBeat

Aug 19, 2026
pulisher
Aug 18, 2026

Prothena (PRTA) Holds Steady Near $8.88 as Shares Sit Between Key Support and ResistancePositive Gamma - vinanet.vn

Aug 18, 2026
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Aug 18, 2026

Prothena (PRTA) 10% holder logs 963K-share gifts - Stock Titan

Aug 18, 2026
pulisher
Aug 12, 2026

Precision Trading with Prothena Corporation Plc (PRTA) Risk Zones - Stock Traders Daily

Aug 12, 2026
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Aug 11, 2026

HC Wainwright Issues Positive Estimate for Prothena Earnings - MarketBeat

Aug 11, 2026
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Aug 08, 2026

Prothena (PRTA) Stock Shrugs Off Revenue Drop As Pipeline Stakes Rise - Sahm

Aug 08, 2026
pulisher
Aug 07, 2026

Prothena Corporation PLC (PRTA) Stock News Today - TradingKey

Aug 07, 2026
pulisher
Aug 07, 2026

PRTA's Q2 Loss Narrower Than Expected, Pipeline Progress in Focus - tradingview.com

Aug 07, 2026
pulisher
Aug 07, 2026

PRTA's Q2 Loss Narrower Than Expected, Pipeline Progress in Focus - Yahoo Finance

Aug 07, 2026
pulisher
Aug 07, 2026

Prothena Reports Second Quarter 2026 Financial Results and Business Highlights - BioSpace

Aug 07, 2026
pulisher
Aug 07, 2026

Prothena (NASDAQ:PRTA) Announces Quarterly Earnings Results, Beats Expectations By $0.03 EPS - MarketBeat

Aug 07, 2026
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Aug 06, 2026

Prothena (PRTA) Reports Q2 Loss, Misses Revenue Estimates - Yahoo Finance

Aug 06, 2026
pulisher
Aug 06, 2026

Prothena Corporation PLC reports results for the quarter ended June 30Earnings Summary - tradingview.com

Aug 06, 2026
pulisher
Aug 06, 2026

Prothena: Q2 Earnings Snapshot - marketscreener.com

Aug 06, 2026
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Aug 06, 2026

Prothena: Q2 Earnings Snapshot - Yahoo Finance

Aug 06, 2026
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Aug 06, 2026

Prothena (NASDAQ: PRTA) turns H1 2026 profit on $50M milestone - Stock Titan

Aug 06, 2026
pulisher
Aug 06, 2026

Prothena Reports Second Quarter 2026 Financial Results and Business Highlights - marketscreener.com

Aug 06, 2026
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Aug 06, 2026

Prothena Reports Second Quarter 2026 Financial Results and Business Highlights - Yahoo Finance

Aug 06, 2026
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Aug 06, 2026

FMR LLC discloses 13.8% Prothena (PRTA) ownership; key fund holds 6.4% - stocktitan.net

Aug 06, 2026
pulisher
Aug 06, 2026

Renaissance Technologies LLC Has $5.91 Million Stock Position in Prothena Corporation plc $PRTA - MarketBeat

Aug 06, 2026

Prothena Corp Plc Stock (PRTA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prothena Corp Plc Stock (PRTA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
SCULLY WILLIAM P
10% Owner
Oct 14 '26
Buy
8.46
10,000
84,569
1,037,000
SCULLY WILLIAM P
10% Owner
Oct 08 '26
Buy
8.57
90,000
770,904
529,000
SCULLY WILLIAM P
10% Owner
Oct 07 '26
Buy
8.40
125,000
1,050,150
439,000
SCULLY WILLIAM P
10% Owner
Oct 02 '26
Buy
8.57
100,000
857,240
314,000
SCULLY WILLIAM P
10% Owner
Sep 29 '26
Buy
8.68
162,000
1,405,674
214,000
SCULLY WILLIAM P
10% Owner
Sep 28 '26
Buy
8.60
103,500
889,872
187,000
SCULLY WILLIAM P
10% Owner
Sep 18 '26
Buy
8.43
100,000
843,460
927,000
SCULLY WILLIAM P
10% Owner
Sep 02 '26
Buy
9.47
27,000
255,739
827,000
SCULLY WILLIAM P
10% Owner
Aug 20 '26
Buy
8.79
50,000
439,430
800,000
SCULLY WILLIAM P
10% Owner
Aug 07 '26
Buy
8.62
3,500
30,167
83,500
$6.58
price down icon 4.22%
$9.94
price down icon 3.21%
$5.53
price down icon 3.66%
$11.27
price down icon 6.16%
$18.60
price down icon 1.74%
WVE WVE
$3.13
price down icon 1.88%
Cap:     |  Volume (24h):