10.82
price up icon1.98%   0.21
after-market After Hours: 10.82
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Prothena Corporation Plc stock is traded at $10.82, with a volume of 409.90K. It is up +1.98% in the last 24 hours and up +17.48% over the past month. Prothena Corp PLC is a late-stage clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. Prothena is developing and applying its proprietary CYTOPE technology to target a broad spectrum of intracellular disease pathways in the brain and periphery. The company's pipeline includes both wholly-owned and partnered programs like Prasinezumab, Coramitug (PRX004), BMS-986446 (PRX005), PRX019, TDP-43 CYTOPE, and PRX012-TfR, being developed for the potential treatment of Parkinson's disease, ATTR amyloidosis with cardiomyopathy, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), and other neurodegenerative diseases.
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Previous Close:
$10.61
Open:
$10.62
24h Volume:
409.90K
Relative Volume:
0.81
Market Cap:
$582.47M
Revenue:
$9.68M
Net Income/Loss:
$-244.09M
P/E Ratio:
-2.3861
EPS:
-4.5346
Net Cash Flow:
$-168.85M
1W Performance:
+1.60%
1M Performance:
+17.48%
6M Performance:
+1.50%
1Y Performance:
+12.83%
1-Day Range:
Value
$10.51
$10.87
1-Week Range:
Value
$10.18
$10.87
52-Week Range:
Value
$4.32
$11.69

Prothena Corporation Plc Stock (PRTA) Company Profile

Name
Name
Prothena Corporation Plc
Name
Phone
011-353-1-236-2500
Name
Address
77 SIR JOHN ROGERSON'S QUAY, BLOCK C, DUBLIN 2
Name
Employee
67
Name
Twitter
@ProthenaCorp
Name
Next Earnings Date
2025-02-18
Name
Latest SEC Filings
Name
PRTA's Discussions on Twitter

Compare PRTA vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRTA icon
PRTA
Prothena Corporation Plc
10.82 571.17M 9.68M -244.09M -168.85M -4.5346
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
441.70 113.01B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
753.93 79.87B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
840.87 51.51B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
333.39 45.29B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
319.94 34.41B 5.36B 287.73M 924.18M 2.5229

Prothena Corporation Plc Stock (PRTA) Upgrades & Downgrades

Date Action Analyst Rating Change
May-28-25 Downgrade BofA Securities Neutral → Underperform
May-27-25 Downgrade Cantor Fitzgerald Overweight → Neutral
May-27-25 Downgrade Jefferies Buy → Hold
May-27-25 Downgrade Oppenheimer Outperform → Perform
Dec-20-24 Initiated Chardan Capital Markets Buy
Jan-30-24 Downgrade BofA Securities Buy → Neutral
Dec-12-23 Initiated Deutsche Bank Buy
Apr-24-23 Initiated SVB Securities Outperform
Jan-27-23 Initiated Piper Sandler Overweight
Nov-04-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-28-22 Upgrade BofA Securities Neutral → Buy
Nov-19-21 Initiated JMP Securities Mkt Outperform
Jun-18-21 Upgrade BofA Securities Underperform → Neutral
Jun-08-21 Reiterated Oppenheimer Outperform
May-26-21 Initiated Citigroup Buy
Feb-26-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-12-21 Upgrade Jefferies Hold → Buy
Feb-02-21 Upgrade BTIG Research Neutral → Buy
Dec-07-20 Initiated H.C. Wainwright Buy
Jul-09-20 Upgrade Oppenheimer Perform → Outperform
Nov-19-19 Upgrade Evercore ISI In-line → Outperform
May-21-18 Downgrade Barclays Equal Weight → Underweight
Apr-23-18 Downgrade Jefferies Buy → Hold
Apr-05-18 Reiterated Barclays Overweight
Nov-20-17 Downgrade Wedbush Outperform → Neutral
Sep-29-17 Reiterated BTIG Research Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-17-17 Initiated Evercore ISI Outperform
Jul-11-17 Initiated Jefferies Buy
Apr-12-17 Initiated Cantor Fitzgerald Overweight
Apr-12-17 Initiated Piper Jaffray Overweight
Mar-02-17 Initiated Instinet Buy
Dec-21-16 Initiated SunTrust Buy
Nov-03-16 Initiated Deutsche Bank Buy
Aug-04-16 Reiterated Barclays Overweight
May-13-16 Initiated Barclays Overweight
Feb-19-16 Reiterated Wedbush Outperform
Jan-21-16 Initiated Credit Suisse Outperform
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Prothena Corporation Plc Stock (PRTA) Latest News

pulisher
Apr 15, 2026

Prothena Corp plc stock (IE00B91XRN20): Why does its biotech pipeline matter more now for investors? - AD HOC NEWS

Apr 15, 2026
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Apr 14, 2026

Prothena FY25 Earnings Review: Partnered Programs Advance Toward Milestones as Wholly-Owned Assets Pivot - AlphaStreet

Apr 14, 2026
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Apr 13, 2026

Prothena Announces Leadership Team Updates - National Today

Apr 13, 2026
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Apr 12, 2026

Chardan Lowers Prothena (PRTA) Price Target Following AFFIRM-AL Trial Failure - MSN

Apr 12, 2026
pulisher
Apr 11, 2026

Why (PRTA) Price Action Is Critical for Tactical Trading - Stock Traders Daily

Apr 11, 2026
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Apr 11, 2026

Prothena Corp PLC (PRTA) Stock Earnings Transcripts - GuruFocus

Apr 11, 2026
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Apr 10, 2026

Prothena (NASDAQ: PRTA) awards 100,000 stock options to Chief Strategy Officer - Stock Titan

Apr 10, 2026
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Apr 10, 2026

Prothena (PRTA) Chief Strategy Officer reports 66,942 shares and option grants - Stock Titan

Apr 10, 2026
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Apr 10, 2026

Prothena (PRTA) Strengthens Leadership Team with Key Promotions - GuruFocus

Apr 10, 2026
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Apr 10, 2026

Prothena promotes Kingston, Isaacs to leadership roles - Investing.com

Apr 10, 2026
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Apr 10, 2026

Prothena promotes Kingston, Isaacs to leadership roles By Investing.com - Investing.com India

Apr 10, 2026
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Apr 10, 2026

PRTA Stock Price, Quote & Chart | PROTHENA CORP PLC (NASDAQ:PRTA) - ChartMill

Apr 10, 2026
pulisher
Apr 09, 2026

Insider Sell: Will Prothena Corporation plc outperform tech stocksQuarterly Investment Review & Verified Swing Trading Watchlist - baoquankhu1.vn

Apr 09, 2026
pulisher
Apr 08, 2026

PRTA Financials: Revenue Breakdown, Margins & Competitor Comparison - Intellectia AI

Apr 08, 2026
pulisher
Apr 06, 2026

Published on: 2026-04-07 04:52:36 - baoquankhu1.vn

Apr 06, 2026
pulisher
Apr 05, 2026

Analyst Calls: How do insiders feel about Prothena Corporation plc2026 Chart Watch & Daily Entry Point Alerts - baoquankhu1.vn

Apr 05, 2026
pulisher
Apr 02, 2026

Gap Down: Can Prothena Corporation plc be recession proofWeekly Trend Report & AI Driven Price Predictions - baoquankhu1.vn

Apr 02, 2026
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Apr 01, 2026

Prothena Corp plc Stock: Clinical Milestones and Strategic Focus in Biotechnology Drive Investor Int - AD HOC NEWS

Apr 01, 2026
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Apr 01, 2026

PRTA Earning Date, Earning Analysis and Earning Prediction - Intellectia AI

Apr 01, 2026
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Apr 01, 2026

PRTA Technical Analysis & Stock Price Forecast - Intellectia AI

Apr 01, 2026
pulisher
Mar 31, 2026

Understanding Momentum Shifts in (PRTA) - Stock Traders Daily

Mar 31, 2026
pulisher
Mar 31, 2026

Top Growth Companies With High Insider Ownership In March 2026 - simplywall.st

Mar 31, 2026
pulisher
Mar 31, 2026

JPMorgan Chase & Co. Buys 608,814 Shares of Prothena Corporation plc $PRTA - MarketBeat

Mar 31, 2026
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Mar 31, 2026

Aug Patterns: Will Prothena Corporation plc outperform its industry peersWeekly Investment Report & Smart Investment Allocation Insights - baoquankhu1.vn

Mar 31, 2026
pulisher
Mar 31, 2026

Stock Recap: Will Prothena Corporation plc benefit from rising consumer demandQuarterly Market Review & Weekly Hot Stock Watchlists - baoquankhu1.vn

Mar 31, 2026
pulisher
Mar 29, 2026

Gainers Report: Will Prothena Corporation plc outperform tech stocks2026 Support & Resistance & Detailed Earnings Play Strategies - baoquankhu1.vn

Mar 29, 2026
pulisher
Mar 27, 2026

Prothena (NASDAQ: PRTA) details 2026 AGM, pay and 2025 pipeline shifts - Stock Titan

Mar 27, 2026
pulisher
Mar 27, 2026

When Can We Expect A Profit From Prothena Corporation plc (NASDAQ:PRTA)? - simplywall.st

Mar 27, 2026
pulisher
Mar 27, 2026

Prothena Corporation plc (NASDAQ:PRTA) Given Consensus Rating of "Hold" by Analysts - MarketBeat

Mar 27, 2026
pulisher
Mar 27, 2026

Prothena Q4 earnings meet estimates, pipeline progress in focus - MSN

Mar 27, 2026
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Mar 26, 2026

Published on: 2026-03-27 01:04:54 - baoquankhu1.vn

Mar 26, 2026
pulisher
Mar 26, 2026

Wall Street Analysts Think Prothena (PRTA) Could Surge 120.19%: Read This Before Placing a Bet - sharewise.com

Mar 26, 2026
pulisher
Mar 25, 2026

Dow Update: Will Prothena Corporation plc benefit from rising consumer demandEntry Point & Low Risk High Reward Trade Ideas - baoquankhu1.vn

Mar 25, 2026
pulisher
Mar 24, 2026

H.C. Wainwright reiterates Prothena stock rating on Parkinson’s data By Investing.com - Investing.com UK

Mar 24, 2026
pulisher
Mar 24, 2026

Prothena (NASDAQ:PRTA) Shares Cross Below Two Hundred Day Moving AverageHere's What Happened - MarketBeat

Mar 24, 2026
pulisher
Mar 23, 2026

Prothena Corp plc stock gains spotlight as partners Roche and Bristol-Myers Squibb showcase key clin - AD HOC NEWS

Mar 23, 2026
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Mar 21, 2026

Prothena Partners Present Data Supporting Next Generation Treatme - The National Law Review

Mar 21, 2026
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Mar 21, 2026

Prothena Partners Present Data Supporting Next Generation Treatments for Parkinson’s and Alzheimer’s Disease at AD/PD™ 2026 - Business Wire

Mar 21, 2026
pulisher
Mar 21, 2026

Prothena Corp plc stock faces pressure amid biotech volatility and pipeline updates - AD HOC NEWS

Mar 21, 2026
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Mar 20, 2026

Prothena authorizes up to $100 million share repurchase plan - MSN

Mar 20, 2026
pulisher
Mar 20, 2026

Avoiding Lag: Real-Time Signals in (PRTA) Movement - Stock Traders Daily

Mar 20, 2026
pulisher
Mar 17, 2026

History Review: Is Prothena Corporation plc attractive for institutional investors2026 Volume Leaders & Fast Momentum Stock Entry Tips - baoquankhu1.vn

Mar 17, 2026
pulisher
Mar 17, 2026

Prothena Corp plc Stock (ISIN: IE00B91XRN20) Faces Biotech Headwinds Amid Pipeline Delays - AD HOC NEWS

Mar 17, 2026
pulisher
Mar 15, 2026

Prothena Corp plc Stock (ISIN: IE00B91XRN20) Faces Headwinds Amid Biotech Volatility - AD HOC NEWS

Mar 15, 2026
pulisher
Mar 14, 2026

Prothena Corporation plc $PRTA Stake Lessened by Prosight Management LP - MarketBeat

Mar 14, 2026
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Mar 13, 2026

Prothena Corp plc Stock (ISIN: IE00B91XRN20) Under Pressure Amid Biotech Volatility - AD HOC NEWS

Mar 13, 2026
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Mar 13, 2026

Citizens reaffirms Prothena stock rating on Novo Nordisk milestone By Investing.com - Investing.com South Africa

Mar 13, 2026
pulisher
Mar 13, 2026

Prothena Corp plc Stock (ISIN: IE00B91XRN20) Faces Pressure Amid Biotech Volatility - AD HOC NEWS

Mar 13, 2026
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Mar 12, 2026

Prothena earns $50M milestone from Novo Nordisk for drug trial - Investing.com Nigeria

Mar 12, 2026
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Mar 12, 2026

IPO Launch: Will Prothena Corporation plc outperform tech stocks2026 Movers & Weekly High Return Forecasts - baoquankhu1.vn

Mar 12, 2026
pulisher
Mar 10, 2026

Prothena (NASDAQ:PRTA) Share Price Passes Above 50-Day Moving AverageTime to Sell? - MarketBeat

Mar 10, 2026

Prothena Corporation Plc Stock (PRTA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$54.26
price up icon 2.69%
$48.70
price down icon 0.25%
$99.47
price up icon 1.08%
$152.54
price up icon 3.76%
$146.74
price down icon 4.34%
ONC ONC
$319.94
price up icon 3.21%
Cap:     |  Volume (24h):