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Prothena Corporation Plc stock is traded at $9.825, with a volume of 256.77K. It is down -1.16% in the last 24 hours and up +2.99% over the past month. Prothena Corp PLC is a clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. The company's clinical pipeline of antibody-based product candidates targets a range of indications, including Amyloid Light-chain (AL) amyloidosis (NEOD001), Parkinson's disease and other related synucleinopathies (PRX002), and inflammatory diseases, including ATTR amyloidosis [Coramitug (PRX004)], Alzheimer's disease (PRX123), Neurodegeneration (PRXPRX019), and Others.
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Previous Close:
$9.94
Open:
$9.92
24h Volume:
256.77K
Relative Volume:
0.42
Market Cap:
$528.88M
Revenue:
$217.25M
Net Income/Loss:
$-50.92M
P/E Ratio:
-9.825
EPS:
-1
Net Cash Flow:
$-100.85M
1W Performance:
+6.22%
1M Performance:
+2.99%
6M Performance:
+47.08%
1Y Performance:
-38.75%
1-Day Range:
Value
$9.68
$10.09
1-Week Range:
Value
$9.24
$10.53
52-Week Range:
Value
$4.32
$16.66

Prothena Corporation Plc Stock (PRTA) Company Profile

Name
Name
Prothena Corporation Plc
Name
Phone
011-353-1-236-2500
Name
Address
77 SIR JOHN ROGERSON'S QUAY, BLOCK C, DUBLIN 2
Name
Employee
163
Name
Twitter
@ProthenaCorp
Name
Next Earnings Date
2025-02-18
Name
Latest SEC Filings
Name
PRTA's Discussions on Twitter

Compare PRTA with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
PRTA
Prothena Corporation Plc
9.825 535.07M 217.25M -50.92M -100.85M -1.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
471.77 120.98B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
768.30 80.15B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
865.84 51.56B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
359.09 47.74B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ONC
Beone Medicines Ltd Adr
335.08 37.38B 4.98B 69.59M 525.67M 0.5197

Prothena Corporation Plc Stock (PRTA) Upgrades & Downgrades

Date Action Analyst Rating Change
May-28-25 Downgrade BofA Securities Neutral → Underperform
May-27-25 Downgrade Cantor Fitzgerald Overweight → Neutral
May-27-25 Downgrade Jefferies Buy → Hold
May-27-25 Downgrade Oppenheimer Outperform → Perform
Dec-20-24 Initiated Chardan Capital Markets Buy
Jan-30-24 Downgrade BofA Securities Buy → Neutral
Dec-12-23 Initiated Deutsche Bank Buy
Apr-24-23 Initiated SVB Securities Outperform
Jan-27-23 Initiated Piper Sandler Overweight
Nov-04-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-28-22 Upgrade BofA Securities Neutral → Buy
Nov-19-21 Initiated JMP Securities Mkt Outperform
Jun-18-21 Upgrade BofA Securities Underperform → Neutral
Jun-08-21 Reiterated Oppenheimer Outperform
May-26-21 Initiated Citigroup Buy
Feb-26-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-12-21 Upgrade Jefferies Hold → Buy
Feb-02-21 Upgrade BTIG Research Neutral → Buy
Dec-07-20 Initiated H.C. Wainwright Buy
Jul-09-20 Upgrade Oppenheimer Perform → Outperform
Nov-19-19 Upgrade Evercore ISI In-line → Outperform
May-21-18 Downgrade Barclays Equal Weight → Underweight
Apr-23-18 Downgrade Jefferies Buy → Hold
Apr-05-18 Reiterated Barclays Overweight
Nov-20-17 Downgrade Wedbush Outperform → Neutral
Sep-29-17 Reiterated BTIG Research Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-17-17 Initiated Evercore ISI Outperform
Jul-11-17 Initiated Jefferies Buy
Apr-12-17 Initiated Cantor Fitzgerald Overweight
Apr-12-17 Initiated Piper Jaffray Overweight
Mar-02-17 Initiated Instinet Buy
Dec-21-16 Initiated SunTrust Buy
Nov-03-16 Initiated Deutsche Bank Buy
Aug-04-16 Reiterated Barclays Overweight
May-13-16 Initiated Barclays Overweight
Feb-19-16 Reiterated Wedbush Outperform
Jan-21-16 Initiated Credit Suisse Outperform
View All

Prothena Corporation Plc Stock (PRTA) Latest News

pulisher
05:07 AM

Prothena (NASDAQ:PRTA) Share Price Crosses Above 50 Day Moving AverageHere's Why - MarketBeat

05:07 AM
pulisher
Jan 24, 2026

Can Calidi Biotherapeutics Inc reach resistance levels soonWeekly Stock Summary & Community Trade Idea Sharing - baoquankhu1.vn

Jan 24, 2026
pulisher
Jan 24, 2026

Trading Systems Reacting to (PRTA) Volatility - Stock Traders Daily

Jan 24, 2026
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Jan 23, 2026

Prothena Corporation Plc (PRTA) Stock Analysis: Evaluating A Potential 96.65% Upside - DirectorsTalk Interviews

Jan 23, 2026
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Jan 22, 2026

Will Prothena Corporation plc benefit from rising consumer demand2025 Market Outlook & Daily Profit Focused Stock Screening - mfd.ru

Jan 22, 2026
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Jan 21, 2026

All You Need to Know About Prothena (PRTA) Rating Upgrade to Buy - Yahoo Finance

Jan 21, 2026
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Jan 20, 2026

Aug Sectors: Will Prothena Corporation plc outperform tech stocks2025 EndofYear Setup & Risk Managed Investment Entry Signals - baoquankhu1.vn

Jan 20, 2026
pulisher
Jan 19, 2026

Recap Report: Will Melar Acquisition Corp I announce a stock split2025 Price Momentum & Precise Entry and Exit Recommendations - baoquankhu1.vn

Jan 19, 2026
pulisher
Jan 17, 2026

Prothena Corporation plc (NASDAQ:PRTA) Sees Significant Growth in Short Interest - MarketBeat

Jan 17, 2026
pulisher
Jan 17, 2026

Prothena Corp (PRTA) Analyst Ratings: RBC Capital's New Price Ta - GuruFocus

Jan 17, 2026
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Jan 16, 2026

Prothena announces board of directors update - MSN

Jan 16, 2026
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Jan 13, 2026

How Prothena Corporation Plc (PRTA) Affects Rotational Strategy Timing - Stock Traders Daily

Jan 13, 2026
pulisher
Jan 13, 2026

Value Recap: What Wall Street predicts for Prothena Corporation plc stock price2025 Pullback Review & Consistent Income Trade Recommendations - Bộ Nội Vụ

Jan 13, 2026
pulisher
Jan 11, 2026

Prothena Corporation plc (NASDAQ:PRTA) Receives Consensus Rating of "Hold" from Brokerages - MarketBeat

Jan 11, 2026
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Jan 09, 2026

Can Prothena Corporation plc stock sustain revenue growthJuly 2025 PostEarnings & Entry Point Strategy Guides - Улправда

Jan 09, 2026
pulisher
Jan 08, 2026

Why hedge funds are buying Prothena Corporation plc stockDay Trade & Daily Entry Point Trade Alerts - Улправда

Jan 08, 2026
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Jan 05, 2026

How Are Partnered Pipelines Rewriting The Prothena (PRTA) Narrative And Price Target Outlook - Yahoo Finance UK

Jan 05, 2026
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Jan 05, 2026

Macro Review: What valuation multiples suggest for Prothena Corporation plc stockWeekly Profit Summary & Long Hold Capital Preservation Plans - Bộ Nội Vụ

Jan 05, 2026
pulisher
Jan 02, 2026

We Think Prothena (NASDAQ:PRTA) Can Afford To Drive Business Growth - Yahoo Finance

Jan 02, 2026
pulisher
Jan 02, 2026

(PRTA) and the Role of Price-Sensitive Allocations - Stock Traders Daily

Jan 02, 2026
pulisher
Dec 25, 2025

89,704 Shares in Prothena Corporation plc $PRTA Acquired by Assenagon Asset Management S.A. - Defense World

Dec 25, 2025
pulisher
Dec 22, 2025

(PRTA) Movement as an Input in Quant Signal Sets - Stock Traders Daily

Dec 22, 2025
pulisher
Dec 21, 2025

Prothena Corporation plc(NasdaqGS:PRTA) added to S&P Biotechnology Select Industry Index - marketscreener.com

Dec 21, 2025
pulisher
Dec 21, 2025

Squarepoint Ops LLC Takes $1.27 Million Position in Prothena Corporation plc $PRTA - Defense World

Dec 21, 2025
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Dec 20, 2025

Earnings Miss: Why Prothena Corporation plc stock remains undervaluedStock Surge & Fast Entry Momentum Trade Alerts - Улправда

Dec 20, 2025
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Dec 19, 2025

Why Prothena Corporation plc stock remains undervaluedDip Buying & Free High Return Stock Watch Alerts - Улправда

Dec 19, 2025
pulisher
Dec 19, 2025

What catalysts could drive Prothena Corporation plc stock higherDip Buying & AI Based Trade Execution Alerts - DonanımHaber

Dec 19, 2025
pulisher
Dec 17, 2025

Prothena Corporation plc (NASDAQ:PRTA) Given Average Recommendation of "Hold" by Analysts - MarketBeat

Dec 17, 2025
pulisher
Dec 13, 2025

Birchview Capital LP Has $2.74 Million Stock Holdings in Prothena Corporation plc $PRTA - MarketBeat

Dec 13, 2025
pulisher
Dec 13, 2025

Prothena Board Member Paula Cobb Resigns - The Globe and Mail

Dec 13, 2025
pulisher
Dec 12, 2025

Paula Cobb steps down from Prothena’s board to join Manifold Bio - Investing.com Nigeria

Dec 12, 2025
pulisher
Dec 12, 2025

Paula Cobb steps down from Prothena’s board to join Manifold Bio By Investing.com - Investing.com South Africa

Dec 12, 2025
pulisher
Dec 12, 2025

[8-K] PROTHENA CORP PUBLIC LTD CO Reports Material Event | PRTA SEC FilingForm 8-K - Stock Titan

Dec 12, 2025
pulisher
Dec 12, 2025

Prothena Announces Board of Directors Update - Yahoo Finance

Dec 12, 2025
pulisher
Dec 12, 2025

What analysts say about Prothena Corporation plc stockMean Reversion Trades & Free Harness Proven Investment Plans - earlytimes.in

Dec 12, 2025
pulisher
Dec 12, 2025

Prothena Corporation plc $PRTA Shares Bought by Federated Hermes Inc. - MarketBeat

Dec 12, 2025
pulisher
Dec 11, 2025

Liquidity Mapping Around (PRTA) Price Events - Stock Traders Daily

Dec 11, 2025
pulisher
Dec 10, 2025

Prothena (PRTA) price target increased by 10.91% to 20.74 - MSN

Dec 10, 2025
pulisher
Dec 10, 2025

Ready to Jump After Recent Trade: Prothena Corporation plc (PRTA) - setenews.com

Dec 10, 2025
pulisher
Dec 06, 2025

How the Narrative Surrounding Prothena Is Changing After New Pipeline and Valuation Updates - Yahoo Finance

Dec 06, 2025
pulisher
Dec 06, 2025

Prothena (PRTA) Price Target Increased by 10.91% to 20.74 - Nasdaq

Dec 06, 2025
pulisher
Dec 05, 2025

Will Prothena Corporation plc stock outperform international peersTrade Entry Summary & Breakout Confirmation Trade Signals - Newser

Dec 05, 2025
pulisher
Dec 04, 2025

Prothena (NASDAQ:PRTA) Stock Price Up 7.4%Here's Why - MarketBeat

Dec 04, 2025
pulisher
Dec 03, 2025

Are Smart Investors Making the Right Decision? Prothena Corporation plc (PRTA) - setenews.com

Dec 03, 2025
pulisher
Dec 02, 2025

Prothena Corp (PRTA) Stock Analysis Report | Ratings, Financials & Performance - Benzinga

Dec 02, 2025
pulisher
Dec 02, 2025

Citizens Jmp Forecasts Strong Price Appreciation for Prothena (NASDAQ:PRTA) Stock - MarketBeat

Dec 02, 2025
pulisher
Dec 02, 2025

Prothena (NASDAQ:PRTA) Price Target Raised to $19.00 at Citizens Jmp - Defense World

Dec 02, 2025
pulisher
Dec 01, 2025

Prothena stock price target raised to $19 from $11 at Citizens - Investing.com Nigeria

Dec 01, 2025
pulisher
Dec 01, 2025

Prothena stock price target raised to $19 from $11 at Citizens By Investing.com - Investing.com South Africa

Dec 01, 2025
pulisher
Dec 01, 2025

Citizens Raises Price Target for Prothena Corp (PRTA) to $19.00 - GuruFocus

Dec 01, 2025
pulisher
Nov 30, 2025

Prothena Corporation plc Stock Analysis and ForecastFundamental Stock Analysis & Double Digit Portfolio Growth - earlytimes.in

Nov 30, 2025

Prothena Corporation Plc Stock (PRTA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prothena Corporation Plc Stock (PRTA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
EcoR1 Capital, LLC
10% Owner
May 06 '25
Sale
7.64
1,984,053
15,164,712
5,304,596
EcoR1 Capital, LLC
10% Owner
May 05 '25
Sale
8.11
977,693
7,930,166
7,288,649
$99.78
price up icon 2.05%
$104.18
price up icon 1.63%
$34.38
price up icon 2.70%
$119.16
price up icon 1.01%
$163.94
price up icon 2.61%
biotechnology ONC
$335.02
price down icon 0.71%
Cap:     |  Volume (24h):