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Prothena Corporation Plc stock is traded at $10.11, with a volume of 86,382. It is up +0.80% in the last 24 hours and up +23.39% over the past month. Prothena Corp PLC is a clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. The company's clinical pipeline of antibody-based product candidates targets a range of indications, including Amyloid Light-chain (AL) amyloidosis (NEOD001), Parkinson's disease and other related synucleinopathies (PRX002), and inflammatory diseases, including ATTR amyloidosis [Coramitug (PRX004)], Alzheimer's disease (PRX123), Neurodegeneration (PRXPRX019), and Others.
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Previous Close:
$10.05
Open:
$10.03
24h Volume:
86,382
Relative Volume:
0.10
Market Cap:
$546.13M
Revenue:
$217.25M
Net Income/Loss:
$-50.92M
P/E Ratio:
-10.11
EPS:
-1
Net Cash Flow:
$-100.85M
1W Performance:
+2.74%
1M Performance:
+23.39%
6M Performance:
-0.88%
1Y Performance:
-41.17%
1-Day Range:
Value
$10.01
$10.21
1-Week Range:
Value
$9.9203
$10.65
52-Week Range:
Value
$4.32
$18.88

Prothena Corporation Plc Stock (PRTA) Company Profile

Name
Name
Prothena Corporation Plc
Name
Phone
011-353-1-236-2500
Name
Address
77 SIR JOHN ROGERSON'S QUAY, BLOCK C, DUBLIN 2
Name
Employee
163
Name
Twitter
@ProthenaCorp
Name
Next Earnings Date
2025-02-18
Name
Latest SEC Filings
Name
PRTA's Discussions on Twitter

Compare PRTA with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
PRTA
Prothena Corporation Plc
10.15 540.99M 217.25M -50.92M -100.85M -1.00
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
406.42 104.55B 11.39B 3.64B 3.50B 13.99
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
464.57 60.36B 2.46B -319.09M -52.09M -2.4669
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REGN
Regeneron Pharmaceuticals Inc
549.52 59.84B 14.21B 4.46B 3.56B 39.69
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ARGX
Argen X Se Adr
800.57 49.07B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ONC
Beone Medicines Ltd Adr
328.93 35.16B 4.56B -176.77M 225.30M -1.7177

Prothena Corporation Plc Stock (PRTA) Upgrades & Downgrades

Date Action Analyst Rating Change
May-28-25 Downgrade BofA Securities Neutral → Underperform
May-27-25 Downgrade Cantor Fitzgerald Overweight → Neutral
May-27-25 Downgrade Jefferies Buy → Hold
May-27-25 Downgrade Oppenheimer Outperform → Perform
Dec-20-24 Initiated Chardan Capital Markets Buy
Jan-30-24 Downgrade BofA Securities Buy → Neutral
Dec-12-23 Initiated Deutsche Bank Buy
Apr-24-23 Initiated SVB Securities Outperform
Jan-27-23 Initiated Piper Sandler Overweight
Nov-04-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-28-22 Upgrade BofA Securities Neutral → Buy
Nov-19-21 Initiated JMP Securities Mkt Outperform
Jun-18-21 Upgrade BofA Securities Underperform → Neutral
Jun-08-21 Reiterated Oppenheimer Outperform
May-26-21 Initiated Citigroup Buy
Feb-26-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-12-21 Upgrade Jefferies Hold → Buy
Feb-02-21 Upgrade BTIG Research Neutral → Buy
Dec-07-20 Initiated H.C. Wainwright Buy
Jul-09-20 Upgrade Oppenheimer Perform → Outperform
Nov-19-19 Upgrade Evercore ISI In-line → Outperform
May-21-18 Downgrade Barclays Equal Weight → Underweight
Apr-23-18 Downgrade Jefferies Buy → Hold
Apr-05-18 Reiterated Barclays Overweight
Nov-20-17 Downgrade Wedbush Outperform → Neutral
Sep-29-17 Reiterated BTIG Research Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-17-17 Initiated Evercore ISI Outperform
Jul-11-17 Initiated Jefferies Buy
Apr-12-17 Initiated Cantor Fitzgerald Overweight
Apr-12-17 Initiated Piper Jaffray Overweight
Mar-02-17 Initiated Instinet Buy
Dec-21-16 Initiated SunTrust Buy
Nov-03-16 Initiated Deutsche Bank Buy
Aug-04-16 Reiterated Barclays Overweight
May-13-16 Initiated Barclays Overweight
Feb-19-16 Reiterated Wedbush Outperform
Jan-21-16 Initiated Credit Suisse Outperform
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Prothena Corporation Plc Stock (PRTA) Latest News

pulisher
05:10 AM

What does recent volatility data suggest for Prothena Corporation plc2025 Technical Patterns & Risk Controlled Daily Trade Plans - newser.com

05:10 AM
pulisher
03:41 AM

Live market analysis of Prothena Corporation plcJuly 2025 Intraday Action & Daily Stock Trend Reports - newser.com

03:41 AM
pulisher
Oct 11, 2025

Tools to monitor Prothena Corporation plc recovery probabilityOptions Play & Long-Term Capital Growth Ideas - newser.com

Oct 11, 2025
pulisher
Oct 10, 2025

Why Prothena Corporation plc stock is seen as undervaluedMarket Performance Report & Daily Stock Momentum Reports - newser.com

Oct 10, 2025
pulisher
Oct 10, 2025

FY2029 EPS Estimates for Prothena Boosted by HC Wainwright - MarketBeat

Oct 10, 2025
pulisher
Oct 10, 2025

Prothena Corporation plc stock volume spike explained2025 Top Decliners & Community Consensus Trade Signals - newser.com

Oct 10, 2025
pulisher
Oct 09, 2025

What data driven models say about Prothena Corporation plc’s futureMarket Weekly Review & Low Drawdown Trading Techniques - newser.com

Oct 09, 2025
pulisher
Oct 09, 2025

What analysts say about Prothena Corporation plc stockAnalyst Downgrades & Build Your Portfolio With Our Free Stock Scanner - earlytimes.in

Oct 09, 2025
pulisher
Oct 08, 2025

Prothena stock price target raised to $20 from $14 at H.C. Wainwright - Investing.com Nigeria

Oct 08, 2025
pulisher
Oct 07, 2025

Prothena Corp. Experiences Revision in Stock Evaluation Amid Market Challenges - Markets Mojo

Oct 07, 2025
pulisher
Oct 07, 2025

Public Employees Retirement System of Ohio Invests $256,000 in Prothena Corporation plc $PRTA - Defense World

Oct 07, 2025
pulisher
Oct 07, 2025

Prothena Corp (PRTA) Sees Raised Price Target by HC Wainwright & Co. | PRTA Stock News - GuruFocus

Oct 07, 2025
pulisher
Oct 06, 2025

Is now a turning point for Prothena Corporation plcBull Run & Safe Capital Growth Stock Tips - newser.com

Oct 06, 2025
pulisher
Oct 05, 2025

Published on: 2025-10-05 07:33:52 - newser.com

Oct 05, 2025
pulisher
Oct 05, 2025

Leading vs lagging indicators on Prothena Corporation plc performance2025 Analyst Calls & Safe Entry Point Alerts - newser.com

Oct 05, 2025
pulisher
Oct 05, 2025

Evaluating Prothena Corporation plc with trendline analysisWeekly Trade Review & Daily Profit Maximizing Tips - newser.com

Oct 05, 2025
pulisher
Oct 03, 2025

Published on: 2025-10-03 05:55:14 - newser.com

Oct 03, 2025
pulisher
Oct 03, 2025

How moving averages guide Prothena Corporation plc tradingJuly 2025 Summary & Free Technical Confirmation Trade Alerts - newser.com

Oct 03, 2025
pulisher
Oct 03, 2025

Prothena Corporation plc (NASDAQ:PRTA) Receives Average Recommendation of "Hold" from Analysts - MarketBeat

Oct 03, 2025
pulisher
Oct 01, 2025

Prothena’s Partner Bristol Myers Squibb Obtains Fast Track Designation from the U.S. FDA for BMS-986 - PharmiWeb.com

Oct 01, 2025
pulisher
Oct 01, 2025

Prothena's partner Bristol Myers Squibb obtains fast track designation from US FDA for BMS-986446 for treatment of Alzheimer's disease - MarketScreener

Oct 01, 2025
pulisher
Oct 01, 2025

Prothena’s Partner Bristol Myers Squibb Obtains Fast Track Designation from the U.S. FDA for BMS-986446 (PRX005), an Anti-MTBR-Tau-Targeting Antibody, for the Treatment of Alzheimer’s Disease - Business Wire

Oct 01, 2025
pulisher
Sep 30, 2025

Hopeful Week For Insiders Who Bought US$2.75m Of Prothena Stock - 富途牛牛

Sep 30, 2025
pulisher
Sep 30, 2025

Published on: 2025-09-30 03:25:21 - newser.com

Sep 30, 2025
pulisher
Sep 29, 2025

Published on: 2025-09-29 17:23:52 - newser.com

Sep 29, 2025

Prothena Corporation Plc Stock (PRTA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prothena Corporation Plc Stock (PRTA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
EcoR1 Capital, LLC
10% Owner
May 06 '25
Sale
7.64
1,984,053
15,164,712
5,304,596
EcoR1 Capital, LLC
10% Owner
May 05 '25
Sale
8.11
977,693
7,930,166
7,288,649
SCULLY WILLIAM P
10% Owner
Jan 14 '25
Buy
12.79
100,000
1,279,040
735,993
SCULLY WILLIAM P
10% Owner
Dec 18 '24
Buy
13.93
73,436
1,022,670
1,297,693
SCULLY WILLIAM P
10% Owner
Dec 31 '24
Buy
13.01
32,000
416,393
650,193
SCULLY WILLIAM P
10% Owner
Dec 20 '24
Buy
15.91
2,000
31,813
618,693
$83.69
price down icon 0.11%
$22.08
price up icon 2.69%
$32.13
price up icon 1.13%
$102.31
price up icon 0.35%
$164.72
price up icon 1.08%
biotechnology ONC
$328.88
price up icon 2.25%
Cap:     |  Volume (24h):