9.39
price up icon0.00%   0.00
after-market After Hours: 9.68 0.29 +3.09%
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Prothena Corp Plc stock is traded at $9.39, with a volume of 248.12K. It is up +0.00% in the last 24 hours and up +7.31% over the past month. Prothena Corp PLC is a late-stage clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. Prothena is developing and applying its proprietary CYTOPE technology to target a broad spectrum of intracellular disease pathways in the brain and periphery. The company's pipeline includes both wholly-owned and partnered programs like Prasinezumab, Coramitug (PRX004), BMS-986446 (PRX005), PRX019, TDP-43 CYTOPE, and PRX012-TfR, being developed for the potential treatment of Parkinson's disease, ATTR amyloidosis with cardiomyopathy, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), and other neurodegenerative diseases.
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Previous Close:
$9.39
Open:
$9.46
24h Volume:
248.12K
Relative Volume:
0.46
Market Cap:
$482.05M
Revenue:
$57.94M
Net Income/Loss:
$-151.18M
P/E Ratio:
-3.3397
EPS:
-2.8116
Net Cash Flow:
$-86.56M
1W Performance:
+5.74%
1M Performance:
+7.31%
6M Performance:
+4.68%
1Y Performance:
+7.07%
1-Day Range:
Value
$9.19
$9.49
1-Week Range:
Value
$8.58
$9.52
52-Week Range:
Value
$7.73
$11.80

Prothena Corp Plc Stock (PRTA) Company Profile

Name
Name
Prothena Corp Plc
Name
Phone
011-353-1-236-2500
Name
Address
77 SIR JOHN ROGERSON'S QUAY, BLOCK C, DUBLIN 2
Name
Employee
67
Name
Twitter
@ProthenaCorp
Name
Next Earnings Date
2026-08-03
Name
Latest SEC Filings
Name
PRTA's Discussions on Twitter

Compare PRTA vs VRTX, REGN, ARGX, MRNA, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRTA icon
PRTA
Prothena Corp Plc
9.39 463.57M 57.94M -151.18M -86.56M -2.8116
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
547.59 136.93B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
828.50 85.11B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
1,011.11 64.95B 4.16B 1.29B 734.26M 19.58
MRNA icon
MRNA
Moderna Inc
138.89 53.23B 2.23B -3.19B -1.60B -8.1462
RVMD icon
RVMD
Revolution Medicines Inc
211.58 45.38B 742.00K -1.37B -1.07B -7.0731

Prothena Corp Plc Stock (PRTA) Upgrades & Downgrades

Date Action Analyst Rating Change
May-28-25 Downgrade BofA Securities Neutral → Underperform
May-27-25 Downgrade Cantor Fitzgerald Overweight → Neutral
May-27-25 Downgrade Jefferies Buy → Hold
May-27-25 Downgrade Oppenheimer Outperform → Perform
Dec-20-24 Initiated Chardan Capital Markets Buy
Jan-30-24 Downgrade BofA Securities Buy → Neutral
Dec-12-23 Initiated Deutsche Bank Buy
Apr-24-23 Initiated SVB Securities Outperform
Jan-27-23 Initiated Piper Sandler Overweight
Nov-04-22 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-28-22 Upgrade BofA Securities Neutral → Buy
Nov-19-21 Initiated JMP Securities Mkt Outperform
Jun-18-21 Upgrade BofA Securities Underperform → Neutral
Jun-08-21 Reiterated Oppenheimer Outperform
May-26-21 Initiated Citigroup Buy
Feb-26-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Feb-12-21 Upgrade Jefferies Hold → Buy
Feb-02-21 Upgrade BTIG Research Neutral → Buy
Dec-07-20 Initiated H.C. Wainwright Buy
Jul-09-20 Upgrade Oppenheimer Perform → Outperform
Nov-19-19 Upgrade Evercore ISI In-line → Outperform
May-21-18 Downgrade Barclays Equal Weight → Underweight
Apr-23-18 Downgrade Jefferies Buy → Hold
Apr-05-18 Reiterated Barclays Overweight
Nov-20-17 Downgrade Wedbush Outperform → Neutral
Sep-29-17 Reiterated BTIG Research Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-17-17 Initiated Evercore ISI Outperform
Jul-11-17 Initiated Jefferies Buy
Apr-12-17 Initiated Cantor Fitzgerald Overweight
Apr-12-17 Initiated Piper Jaffray Overweight
Mar-02-17 Initiated Instinet Buy
Dec-21-16 Initiated SunTrust Buy
Nov-03-16 Initiated Deutsche Bank Buy
Aug-04-16 Reiterated Barclays Overweight
May-13-16 Initiated Barclays Overweight
Feb-19-16 Reiterated Wedbush Outperform
Jan-21-16 Initiated Credit Suisse Outperform
View All

Prothena Corp Plc Stock (PRTA) Latest News

pulisher
Aug 21, 2026

Prothena (NASDAQ:PRTA) Major Shareholder Buys 50,000 Shares of Stock - MarketBeat

Aug 21, 2026
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Aug 19, 2026

Prothena (NASDAQ:PRTA) Shares Pass Below Two Hundred Day Moving AverageShould You Sell? - MarketBeat

Aug 19, 2026
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Aug 12, 2026

Precision Trading with Prothena Corporation Plc (PRTA) Risk Zones - Stock Traders Daily

Aug 12, 2026
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Aug 11, 2026

HC Wainwright Issues Positive Estimate for Prothena Earnings - MarketBeat

Aug 11, 2026
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Aug 08, 2026

Prothena (PRTA) Stock Shrugs Off Revenue Drop As Pipeline Stakes Rise - Sahm

Aug 08, 2026
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Aug 07, 2026

Prothena Corporation PLC (PRTA) Stock News Today - TradingKey

Aug 07, 2026
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Aug 07, 2026

PRTA's Q2 Loss Narrower Than Expected, Pipeline Progress in Focus - tradingview.com

Aug 07, 2026
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Aug 07, 2026

Prothena (NASDAQ:PRTA) Announces Quarterly Earnings Results, Beats Expectations By $0.03 EPS - MarketBeat

Aug 07, 2026
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Aug 06, 2026

Prothena (PRTA) Reports Q2 Loss, Misses Revenue Estimates - Yahoo Finance

Aug 06, 2026
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Aug 06, 2026

Prothena Corporation PLC reports results for the quarter ended June 30Earnings Summary - tradingview.com

Aug 06, 2026
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Aug 06, 2026

Prothena: Q2 Earnings Snapshot - marketscreener.com

Aug 06, 2026
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Aug 06, 2026

Prothena (NASDAQ: PRTA) turns H1 2026 profit on $50M milestone - Stock Titan

Aug 06, 2026
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Aug 06, 2026

Prothena Reports Second Quarter 2026 Financial Results and Business Highlights - marketscreener.com

Aug 06, 2026
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Aug 06, 2026

FMR LLC discloses 13.8% Prothena (PRTA) ownership; key fund holds 6.4% - stocktitan.net

Aug 06, 2026
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Aug 06, 2026

Renaissance Technologies LLC Has $5.91 Million Stock Position in Prothena Corporation plc $PRTA - MarketBeat

Aug 06, 2026
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Aug 04, 2026

Prothena Corporation PLC expected to post a loss of 39 cents a shareEarnings Preview - tradingview.com

Aug 04, 2026
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Aug 01, 2026

Technical Reactions to PRTA Trends in Macro Strategies - Stock Traders Daily

Aug 01, 2026
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Jul 31, 2026

Prothena (NASDAQ:PRTA) Insider Anne Evans Kingston Sells 7,662 Shares of Stock - MarketBeat

Jul 31, 2026
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Jul 30, 2026

Prothena Corp PLC (PRTA) Chief Strategy Officer Anne Kingston Se - GuruFocus

Jul 30, 2026
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Jul 30, 2026

Prothena Q2 Results: Financial data release set for Aug 6 - scanx.trade

Jul 30, 2026
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Jul 29, 2026

BlackRock (PRTA holder) discloses 6.9% beneficial stake in Prothena common stock - Stock Titan

Jul 29, 2026
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Jul 28, 2026

Prothena Corp. Plc Revenue Breakdown – LSX:A1KAVV - TradingView

Jul 28, 2026
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Jul 28, 2026

Rubric Capital Management LP Has $48.60 Million Position in Prothena Corporation plc $PRTA - MarketBeat

Jul 28, 2026
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Jul 27, 2026

Prothena Corporation PLC (PRTA) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jul 27, 2026
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Jul 27, 2026

Prothena (PRTA) Expected to Announce Quarterly Earnings on Monday - MarketBeat

Jul 27, 2026
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Jul 24, 2026

PRTA|Prothena Corporation PLC|Price:8.720|Chg%:-0.030 - TradingKey

Jul 24, 2026
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Jul 21, 2026

Prothena stock trades steady as Alzheimer portfolio advances and earnings show growing R&D investmen - Ad-hoc-news.de

Jul 21, 2026
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Jul 20, 2026

Trading the Move, Not the Narrative: (PRTA) Edition - Stock Traders Daily

Jul 20, 2026
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Jul 15, 2026

Michael John Isaacs Net Worth (2026) - GuruFocus

Jul 15, 2026
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Jul 13, 2026

Prothena (PRTA) Price Target Increased by 37.50% to 16.83 - msn.com

Jul 13, 2026
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Jul 09, 2026

PRTA Stock Rises Nearly 11% in Six Months: What's Driving It? - Yahoo Finance

Jul 09, 2026
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Jul 07, 2026

Prothena Corp plc updates investors on pipeline progress as neurodegeneration focus deepens - ad-hoc-news.de

Jul 07, 2026
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Jul 07, 2026

Transthyretin Amyloidosis Treatment Market Size to Reach USD 35.10 Billion by 2035, Growing at a 14.64% CAGR | SNS Insider - GlobeNewswire Inc.

Jul 07, 2026
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Jul 04, 2026

Price to sales forward of Prothena Corporation plc – NASDAQ:PRTA - tradingview.com

Jul 04, 2026
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Jul 02, 2026

PRTAProthena Corp Plc Options - Finviz

Jul 02, 2026
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Jun 27, 2026

Price to sales forward of Prothena Corp. Plc – MUN:0PT - TradingView

Jun 27, 2026
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Jun 27, 2026

Enterprise value to revenue forward of Prothena Corporation plc – NASDAQ:PRTA - TradingView

Jun 27, 2026
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Jun 27, 2026

Enterprise value to EBIT forward of Prothena Corporation plc – NASDAQ:PRTA - TradingView

Jun 27, 2026
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Jun 27, 2026

Price to book forward of Prothena Corp. Plc – MUN:0PT - TradingView

Jun 27, 2026
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Jun 26, 2026

Enterprise value to EBITDA forward of Prothena Corp. Plc – MUN:0PT - TradingView

Jun 26, 2026
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Jun 26, 2026

Enterprise value to revenue forward of Prothena Corp. Plc – MUN:0PT - TradingView

Jun 26, 2026
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Jun 26, 2026

Prothena Corp, Parkinson antibody program draws attention for the stock - ad-hoc-news.de

Jun 26, 2026
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Jun 26, 2026

Prothena Corp. Plc Actuals & Estimates (NASDAQ:PRTA) - TradingView

Jun 26, 2026
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Jun 26, 2026

Prothena Corp. Plc Actuals & Estimates (DUS:0PT) - TradingView

Jun 26, 2026
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Jun 25, 2026

Prothena Corp. Plc Actuals & Estimates (SWB:0PT) - TradingView

Jun 25, 2026
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Jun 25, 2026

PRTA Forecast — Price Target — Prediction for 2027 - TradingView

Jun 25, 2026
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Jun 25, 2026

0PT Forecast — Price Target — Prediction for 2027 - TradingView

Jun 25, 2026
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Jun 24, 2026

Prothena Corporation PLC (PRTA) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jun 24, 2026
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Jun 23, 2026

Prothena Corporation Plc (NASDAQ:PRTA) About To Shift From Loss To Profit - Moomoo

Jun 23, 2026
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Jun 22, 2026

Prothena Corp plc strategy in focus, shares watched against biotech peers - AD HOC NEWS

Jun 22, 2026
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Jun 18, 2026

Prothena Corporation PLC (PRTA) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

Jun 18, 2026

Prothena Corp Plc Stock (PRTA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prothena Corp Plc Stock (PRTA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
SCULLY WILLIAM P
10% Owner
Aug 07 '26
Buy
8.62
34,000
293,053
790,000
SCULLY WILLIAM P
10% Owner
Aug 07 '26
Buy
8.62
3,500
30,167
83,500
Kingston Anne Evans
Chief Strategy Officer
Jul 29 '26
Sale
8.47
7,662
64,919
55,782
Isaacs Michael John
General Counsel & Company Sec.
Jul 29 '26
Sale
8.47
8,386
71,055
35,745
$123.98
price up icon 0.00%
$61.33
price up icon 0.03%
$112.82
price down icon 3.22%
$236.01
price down icon 0.09%
ONC ONC
$371.98
price down icon 0.66%
$211.58
price up icon 1.01%
Cap:     |  Volume (24h):