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Prelude Therapeutics Inc stock is traded at $1.27, with a volume of 52,890. It is down -0.79% in the last 24 hours and up +10.62% over the past month. Prelude Therapeutics Incorp is a clinical stage precision oncology company focused on discovering and developing small molecule therapies optimized to target the key driver mechanisms in cancers with high unmet needs. The company's pipeline includes four candidates currently in clinical development: PRT1419, a potent, selective inhibitor of MCL1; PRT2527, a potent and selective CDK9 inhibitor, PRT3645, a next-generation CDK4/6 inhibitor, and PRT3789 a first-in-class SMARCA2/BRM protein degrader.
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Previous Close:
$1.26
Open:
$1.25
24h Volume:
52,890
Relative Volume:
0.25
Market Cap:
$71.88M
Revenue:
-
Net Income/Loss:
$-131.52M
P/E Ratio:
-0.7135
EPS:
-1.78
Net Cash Flow:
$-107.56M
1W Performance:
-14.38%
1M Performance:
+10.62%
6M Performance:
+76.50%
1Y Performance:
-36.06%
1-Day Range:
Value
$1.20
$1.28
1-Week Range:
Value
$1.15
$1.4969
52-Week Range:
Value
$0.6101
$2.01

Prelude Therapeutics Inc Stock (PRLD) Company Profile

Name
Name
Prelude Therapeutics Inc
Name
Phone
(302) 467-1280
Name
Address
175 INNOVATION BOULEVARD, WILMINGTON
Name
Employee
131
Name
Twitter
Name
Next Earnings Date
2024-10-30
Name
Latest SEC Filings
Name
PRLD's Discussions on Twitter

Compare PRLD with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
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PRLD
Prelude Therapeutics Inc
1.27 71.32M 0 -131.52M -107.56M -1.78
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VRTX
Vertex Pharmaceuticals Inc
407.62 104.55B 11.39B 3.64B 3.50B 13.99
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ALNY
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472.68 60.36B 2.46B -319.09M -52.09M -2.4669
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Regeneron Pharmaceuticals Inc
552.20 59.84B 14.21B 4.46B 3.56B 39.69
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ARGX
Argen X Se Adr
809.14 49.07B 3.06B 1.28B 447.35M 19.67
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ONC
Beone Medicines Ltd Adr
331.45 35.16B 4.56B -176.77M 225.30M -1.7177

Prelude Therapeutics Inc Stock (PRLD) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-19-24 Upgrade H.C. Wainwright Neutral → Buy
Jun-20-24 Downgrade Barclays Equal Weight → Underweight
Mar-13-24 Initiated JMP Securities Mkt Outperform
Feb-20-24 Downgrade H.C. Wainwright Buy → Neutral
Dec-19-23 Downgrade Morgan Stanley Equal-Weight → Underweight
Nov-21-22 Downgrade BofA Securities Neutral → Underperform
Sep-09-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Jul-29-22 Initiated Jefferies Buy
Mar-15-22 Downgrade BofA Securities Buy → Neutral
Feb-28-22 Downgrade Barclays Overweight → Equal Weight
Oct-08-21 Upgrade Morgan Stanley Equal-Weight → Overweight
Jul-27-21 Upgrade BofA Securities Neutral → Buy
Apr-26-21 Initiated H.C. Wainwright Buy
Mar-09-21 Initiated Barclays Overweight
Nov-20-20 Downgrade BofA Securities Buy → Neutral
Oct-20-20 Initiated BofA Securities Buy
Oct-20-20 Initiated Goldman Neutral
Oct-20-20 Initiated Morgan Stanley Equal-Weight
View All

Prelude Therapeutics Inc Stock (PRLD) Latest News

pulisher
08:45 AM

Is Prelude Therapeutics Incorporated stock a defensive play in 2025Gap Down & Fast Entry and Exit Trade Plans - newser.com

08:45 AM
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Can Prelude Therapeutics Incorporated stock maintain operating marginsMarket Risk Summary & Fast Moving Market Watchlists - newser.com

04:46 AM
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04:02 AM

Using Bollinger Bands to evaluate Prelude Therapeutics IncorporatedMarket Sentiment Summary & High Return Trade Opportunity Guides - newser.com

04:02 AM
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01:25 AM

Will Prelude Therapeutics Incorporated stock deliver shareholder value2025 Price Targets & High Return Stock Watch Alerts - newser.com

01:25 AM
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12:18 PM

Can Prelude Therapeutics Incorporated stock sustain free cash flow growthQuarterly Profit Summary & Safe Capital Growth Stock Tips - newser.com

12:18 PM
pulisher
Oct 09, 2025

Published on: 2025-10-09 05:09:32 - newser.com

Oct 09, 2025
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Oct 09, 2025

Can momentum traders help lift Prelude Therapeutics IncorporatedEarnings Summary Report & AI Driven Price Predictions - newser.com

Oct 09, 2025
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Oct 09, 2025

Using economic indicators to assess Prelude Therapeutics Incorporated potentialFed Meeting & Safe Capital Allocation Plans - newser.com

Oct 09, 2025
pulisher
Oct 09, 2025

Published on: 2025-10-09 02:10:25 - newser.com

Oct 09, 2025
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Oct 09, 2025

Analyzing Prelude Therapeutics Incorporated with risk reward ratio charts2025 Big Picture & Free Safe Capital Growth Stock Tips - newser.com

Oct 09, 2025
pulisher
Oct 06, 2025

CDK4/6 Inhibitor Market Positioned for Remarkable Growth as Revolutionary Therapies Transform Cancer Treatment Landscape in 2024 - Barchart.com

Oct 06, 2025
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Oct 05, 2025

Full technical analysis of Prelude Therapeutics Incorporated stock2025 Bull vs Bear & Daily Growth Stock Investment Tips - newser.com

Oct 05, 2025
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Oct 05, 2025

Will Prelude Therapeutics Incorporated rebound enough to break evenEarnings Risk Report & Fast Momentum Entry Tips - newser.com

Oct 05, 2025
pulisher
Oct 03, 2025

Multi asset correlation models including Prelude Therapeutics IncorporatedInsider Buying & Weekly Watchlist for Consistent Profits - newser.com

Oct 03, 2025
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Oct 03, 2025

Will earnings trigger a reversal in Prelude Therapeutics IncorporatedPortfolio Return Summary & Verified Swing Trading Watchlists - newser.com

Oct 03, 2025
pulisher
Oct 02, 2025

What drives Prelude Therapeutics Incorporated stock priceSector-Based Investing & Double Digit Trading Ideas - earlytimes.in

Oct 02, 2025
pulisher
Sep 28, 2025

Contrasting Cardiol Therapeutics (NASDAQ:CRDL) & Prelude Therapeutics (NASDAQ:PRLD) - Defense World

Sep 28, 2025
pulisher
Sep 27, 2025

Prelude Therapeutics (NASDAQ:PRLD) versus Talphera (NASDAQ:TLPH) Financial Contrast - Defense World

Sep 27, 2025
pulisher
Sep 26, 2025

3 Promising Penny Stocks With Over $60M Market Cap - simplywall.st

Sep 26, 2025
pulisher
Sep 26, 2025

Brokers Set Expectations for PRLD Q3 Earnings - Defense World

Sep 26, 2025
pulisher
Sep 24, 2025

Prelude Therapeutics’ (PRLD) “Buy” Rating Reaffirmed at HC Wainwright - Defense World

Sep 24, 2025
pulisher
Sep 23, 2025

H.C. Wainwright reiterates Buy rating on Prelude Therapeutics stock with $5 target - Investing.com Canada

Sep 23, 2025
pulisher
Sep 23, 2025

Prelude Therapeutics (NASDAQ:PRLD) Receives Buy Rating from HC Wainwright - MarketBeat

Sep 23, 2025
pulisher
Sep 23, 2025

HC Wainwright & Co. Reiterates Buy Rating for PRLD, Price Target at $5.00 | PRLD Stock News - GuruFocus

Sep 23, 2025
pulisher
Sep 22, 2025

New PROTACs revealed in Prelude Therapeutics patent - BioWorld MedTech

Sep 22, 2025
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Sep 21, 2025

What momentum shifts mean for Prelude Therapeutics IncorporatedInsider Selling & Weekly Return Optimization Plans - newser.com

Sep 21, 2025
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Sep 21, 2025

Will Prelude Therapeutics Incorporated benefit from macro trendsWeekly Trend Summary & Entry Point Confirmation Signals - newser.com

Sep 21, 2025
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Sep 20, 2025

Statistical indicators supporting Prelude Therapeutics Incorporated’s strength2025 Investor Takeaways & Consistent Growth Stock Picks - newser.com

Sep 20, 2025
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Sep 20, 2025

Visual analytics tools that track Prelude Therapeutics Incorporated performance2025 Investor Takeaways & Safe Entry Momentum Tips - newser.com

Sep 20, 2025
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Sep 20, 2025

New Highs: Is Prelude Therapeutics Incorporated stock a good pick for beginnersJuly 2025 Review & Consistent Profit Focused Trading Strategies - خودرو بانک

Sep 20, 2025
pulisher
Sep 19, 2025

Profit Recap: Will Prelude Therapeutics Incorporated stock go up in YEARWeekly Trade Analysis & Breakout Confirmation Trade Signals - خودرو بانک

Sep 19, 2025
pulisher
Sep 19, 2025

Prelude Therapeutics regains Nasdaq compliance with minimum bid price rule - Investing.com Canada

Sep 19, 2025
pulisher
Sep 19, 2025

Custom watchlist performance reports with Prelude Therapeutics IncorporatedQuarterly Portfolio Review & Weekly High Potential Alerts - newser.com

Sep 19, 2025
pulisher
Sep 19, 2025

How hedge fund analytics apply to Prelude Therapeutics Incorporated stockDip Buying & Long-Term Capital Growth Strategies - newser.com

Sep 19, 2025

Prelude Therapeutics Inc Stock (PRLD) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prelude Therapeutics Inc Stock (PRLD) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Vaddi Krishna
CEO
Mar 25 '25
Buy
0.69
675,000
467,438
1,999,296
Vaddi Krishna
CEO
Mar 21 '25
Buy
0.73
15,000
10,959
1,324,296
Vaddi Krishna
CEO
Mar 20 '25
Buy
0.73
5,416
3,950
1,309,296
Vaddi Krishna
CEO
Mar 14 '25
Buy
0.75
29,999
22,631
1,294,774
Vaddi Krishna
CEO
Mar 17 '25
Buy
0.75
9,106
6,829
1,303,880
Vaddi Krishna
CEO
Mar 13 '25
Buy
0.72
50,000
35,820
1,264,775
Vaddi Krishna
CEO
Mar 12 '25
Buy
0.71
47,500
33,744
1,214,775
Vaddi Krishna
CEO
Dec 31 '24
Buy
1.21
5,000
6,044
142,553
Vaddi Krishna
CEO
Dec 30 '24
Buy
1.20
10,000
12,000
137,553
Combs Andrew
Chief Chemistry Officer
Dec 23 '24
Buy
1.37
60,000
82,002
377,623
$84.69
price up icon 1.10%
$22.76
price up icon 6.16%
$32.50
price up icon 2.17%
$102.23
price up icon 0.32%
$166.15
price up icon 2.29%
biotechnology ONC
$331.45
price up icon 3.60%
Cap:     |  Volume (24h):