4.27
price down icon1.39%   -0.06
after-market After Hours: 4.22 -0.05 -1.17%
loading
Prelude Therapeutics Inc stock is traded at $4.27, with a volume of 241.37K. It is down -1.39% in the last 24 hours and down -0.93% over the past month. Prelude Therapeutics Incorp is a precision oncology company developing medicines in areas of high unmet need for cancer patients. Its pipeline features selective KAT6A degraders and mutant selective JAK2V617F JH2 inhibitors, new approaches to clinically validated targets with transformative potential for patients. The company is also leveraging its expertise in targeted protein degradation to discover and develop next-generation degrader antibody conjugates (DACs) with novel payloads.
See More
Previous Close:
$4.33
Open:
$4.37
24h Volume:
241.37K
Relative Volume:
0.61
Market Cap:
$340.09M
Revenue:
$16.72M
Net Income/Loss:
$-77.80M
P/E Ratio:
-4.0386
EPS:
-1.0573
Net Cash Flow:
$-43.78M
1W Performance:
-4.69%
1M Performance:
-0.93%
6M Performance:
+155.69%
1Y Performance:
+374.39%
1-Day Range:
Value
$4.16
$4.52
1-Week Range:
Value
$3.95
$4.75
52-Week Range:
Value
$0.75
$5.54

Prelude Therapeutics Inc Stock (PRLD) Company Profile

Name
Name
Prelude Therapeutics Inc
Name
Phone
(302) 467-1280
Name
Address
175 INNOVATION BOULEVARD, WILMINGTON
Name
Employee
79
Name
Twitter
Name
Next Earnings Date
2026-05-12
Name
Latest SEC Filings
Name
PRLD's Discussions on Twitter

Compare PRLD vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRLD icon
PRLD
Prelude Therapeutics Inc
4.27 344.86M 16.72M -77.80M -43.78M -1.0573
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
434.52 110.03B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
638.88 67.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
806.46 50.76B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
297.45 40.12B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
151.56 32.68B 742.00K -1.37B -1.07B -7.0731

Prelude Therapeutics Inc Stock (PRLD) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-19-24 Upgrade H.C. Wainwright Neutral → Buy
Jun-20-24 Downgrade Barclays Equal Weight → Underweight
Mar-13-24 Initiated JMP Securities Mkt Outperform
Feb-20-24 Downgrade H.C. Wainwright Buy → Neutral
Dec-19-23 Downgrade Morgan Stanley Equal-Weight → Underweight
Nov-21-22 Downgrade BofA Securities Neutral → Underperform
Sep-09-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Jul-29-22 Initiated Jefferies Buy
Mar-15-22 Downgrade BofA Securities Buy → Neutral
Feb-28-22 Downgrade Barclays Overweight → Equal Weight
Oct-08-21 Upgrade Morgan Stanley Equal-Weight → Overweight
Jul-27-21 Upgrade BofA Securities Neutral → Buy
Apr-26-21 Initiated H.C. Wainwright Buy
Mar-09-21 Initiated Barclays Overweight
Nov-20-20 Downgrade BofA Securities Buy → Neutral
Oct-20-20 Initiated BofA Securities Buy
Oct-20-20 Initiated Goldman Neutral
Oct-20-20 Initiated Morgan Stanley Equal-Weight
View All

Prelude Therapeutics Inc Stock (PRLD) Latest News

pulisher
May 19, 2026

New PROTACs reported in Prelude Therapeutics patent - BioWorld News

May 19, 2026
pulisher
May 17, 2026

Prelude Therapeutics Incorporated (NASDAQ:PRLD) Reported Earnings Last Week And Analysts Are Already Upgrading Their Estimates - Sahm

May 17, 2026
pulisher
May 16, 2026

Earnings Beat: Prelude Therapeutics Incorporated (NASDAQ:PRLD) Just Beat Analyst Forecasts, And Analysts Have Been Lifting Their Forecasts - Yahoo Finance

May 16, 2026
pulisher
May 15, 2026

Goldman Sachs initiates Prelude Therapeutics stock coverage as Early-Stage Biotech - Investing.com India

May 15, 2026
pulisher
May 13, 2026

Prelude Therapeutics (PRLD) Losses Narrow In Q1 2026 Challenging Bearish Narratives - Sahm

May 13, 2026
pulisher
May 12, 2026

TradingKey - TradingKey

May 12, 2026
pulisher
May 12, 2026

Jefferies raises Prelude Therapeutics stock price target on pipeline progress By Investing.com - Investing.com Australia

May 12, 2026
pulisher
May 12, 2026

Prelude (PRLD) Reports Progress on Strategic Initiatives and Cas - GuruFocus

May 12, 2026
pulisher
May 12, 2026

Prelude Therapeutics Reports Q1 2026 Results, Advances Precision Oncology Pipeline and Extends Cash Runway to 2028 - Minichart

May 12, 2026
pulisher
May 12, 2026

Prelude Therapeutics (NASDAQ:PRLD) Reports Narrower Quarterly Loss, Shares Rise on Cash Runway Extension - ChartMill

May 12, 2026
pulisher
May 12, 2026

Prelude Therapeutics Inc 1Q 2026: Revenue $4.58M, EPS $(0.13) — 10-Q Summary - TradingView

May 12, 2026
pulisher
May 12, 2026

Prelude Therapeutics Initiates Phase 1 Study of PRT12396 and Provides R&D Pipeline Update - Quiver Quantitative

May 12, 2026
pulisher
May 12, 2026

Prelude Therapeutics Q1 net loss narrows as expenses fall - TradingView

May 12, 2026
pulisher
May 12, 2026

Prelude Therapeutics (NASDAQ: PRLD) trims Q1 2026 loss and extends cash runway to 2028 - Stock Titan

May 12, 2026
pulisher
May 12, 2026

Prelude Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update - Weekly Voice

May 12, 2026
pulisher
May 12, 2026

Prelude Therapeutics: Current Cash Runway Into 2Q 2028 >PRLD - Moomoo

May 12, 2026
pulisher
May 11, 2026

Prelude Therapeutics Is Maintained at Buy by HC Wainwright & Co. - Moomoo

May 11, 2026
pulisher
May 08, 2026

Wall Street Analysts Think Prelude Therapeutics (PRLD) Could Surge 33.59%: Read This Before Placing a Bet - Yahoo Finance

May 08, 2026
pulisher
May 08, 2026

Prelude Therapeutics Inc expected to post a loss of 24 cents a shareEarnings Preview - TradingView

May 08, 2026
pulisher
May 05, 2026

PRLD Initiates Coverage On Prelude Therapeutics -- Price Target Announced at $9.00 - GuruFocus

May 05, 2026
pulisher
May 04, 2026

D. Boral Capital Initiates Prelude Therapeutics(PRLD.US) With Buy Rating, Announces Target Price $9 - Moomoo

May 04, 2026
pulisher
May 04, 2026

D Boral Capital initiates coverage of Prelude Therapeutics (PRLD) with buy recommendation - MSN

May 04, 2026
pulisher
May 03, 2026

Prelude Therapeutics (PRLD) price target increased by 19.35% to 6.29 - MSN

May 03, 2026
pulisher
May 01, 2026

Prelude Therapeutics (PRLD) Presents Preclinical Data for KAT6A Degarader PRT13722 in Breast Cancer - Yahoo Finance

May 01, 2026
pulisher
Apr 30, 2026

Prelude Therapeutics (NASDAQ:PRLD) Rating Increased to Hold at Zacks Research - MarketBeat

Apr 30, 2026
pulisher
Apr 29, 2026

Prelude Therapeutics (NASDAQ: PRLD) outlines 2026 proxy votes on directors, pay and auditor - Stock Titan

Apr 29, 2026
pulisher
Apr 29, 2026

Short Interest in Prelude Therapeutics Incorporated (NASDAQ:PRLD) Decreases By 22.1% - MarketBeat

Apr 29, 2026
pulisher
Apr 29, 2026

HC Wainwright Issues Positive Estimate for PRLD Earnings - MarketBeat

Apr 29, 2026
pulisher
Apr 28, 2026

RA Capital reports 7.88M-share Prelude Therapeutics (PRLD) stake - Stock Titan

Apr 28, 2026
pulisher
Apr 28, 2026

Prelude Therapeutics (PRLD) Expected to Announce Quarterly Earnings on Tuesday - MarketBeat

Apr 28, 2026
pulisher
Apr 28, 2026

H.C. Wainwright raises Prelude Therapeutics price target to $8 By Investing.com - Investing.com Canada

Apr 28, 2026
pulisher
Apr 27, 2026

PRLD Maintained by HC Wainwright & Co. -- Price Target Raised to $8 - GuruFocus

Apr 27, 2026
pulisher
Apr 27, 2026

HC Wainwright Issues Positive Forecast for Prelude Therapeutics (NASDAQ:PRLD) Stock Price - MarketBeat

Apr 27, 2026
pulisher
Apr 24, 2026

Thursday’s insider trading: Major buys at Prelude, sells at NuScale - Investing.com

Apr 24, 2026
pulisher
Apr 23, 2026

Prelude Therapeutics (NASDAQ:PRLD) Director David Bonita Buys 2,815,315 Shares - MarketBeat

Apr 23, 2026
pulisher
Apr 23, 2026

Prelude Therapeutics (NASDAQ:PRLD) Director Buys $12,499,998.60 in Stock - MarketBeat

Apr 23, 2026
pulisher
Apr 23, 2026

Insider Purchase: Director at $PRLD Buys 1,689,189 Shares - Moomoo

Apr 23, 2026
pulisher
Apr 23, 2026

Orbimed entities acquire $12.5m in Prelude Therapeutics stock By Investing.com - Investing.com Canada

Apr 23, 2026
pulisher
Apr 23, 2026

Prelude Therapeutics director David P. Bonita acquires $12.5 million in stock - Investing.com

Apr 23, 2026
pulisher
Apr 23, 2026

Prelude Therapeutics director David P. Bonita acquires $12.5 million in stock By Investing.com - Investing.com South Africa

Apr 23, 2026
pulisher
Apr 23, 2026

Orbimed entities acquire $12.5m in Prelude Therapeutics stock - Investing.com

Apr 23, 2026
pulisher
Apr 23, 2026

OrbiMed funds add Prelude Therapeutics (PRLD) shares at $4.44 in offering - Stock Titan

Apr 23, 2026
pulisher
Apr 23, 2026

OrbiMed funds boost Prelude Therapeutics (NASDAQ: PRLD) stake with 2.82M-share buy - Stock Titan

Apr 23, 2026
pulisher
Apr 21, 2026

Prelude Therapeutics Enters Underwriting for $85.5 Million Equity Offering Led by RA Capital - TradingView

Apr 21, 2026
pulisher
Apr 20, 2026

Prelude Therapeutics (PRLD) Unveils Promising Preclinical Data f - GuruFocus

Apr 20, 2026
pulisher
Apr 20, 2026

Prelude Therapeutics (PRLD) Launches $90M Public Offering with S - GuruFocus

Apr 20, 2026
pulisher
Apr 20, 2026

Prelude Therapeutics Shares Rise on Positive Preclinical Data for Breast Cancer Drug - Moomoo

Apr 20, 2026
pulisher
Apr 20, 2026

Prelude Therapeutics Unveils Promising Preclinical Data for First-in-Class Oral KAT6A Degrader PRT13722 in HR+/HER2- Breast Cancer at AACR 2026 12 - Minichart

Apr 20, 2026

Prelude Therapeutics Inc Stock (PRLD) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading

Prelude Therapeutics Inc Stock (PRLD) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
ORBIMED ADVISORS LLC
Director
Apr 21 '26
Buy
4.44
2,815,315
12,499,999
11,808,945
$29.96
price down icon 2.98%
$106.24
price down icon 3.00%
$92.14
price up icon 1.33%
$54.50
price up icon 1.77%
ONC ONC
$310.25
price up icon 0.20%
$151.56
price down icon 1.41%
Cap:     |  Volume (24h):