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Prelude Therapeutics Inc stock is traded at $5.035, with a volume of 132.19K. It is up +2.31% in the last 24 hours and up +31.84% over the past month. Prelude Therapeutics Incorp is a precision oncology company developing medicines in areas of high unmet need for cancer patients. Its pipeline features selective KAT6A degraders and mutant selective JAK2V617F JH2 inhibitors, new approaches to clinically validated targets with transformative potential for patients. The company is also leveraging its expertise in targeted protein degradation to discover and develop next-generation degrader antibody conjugates (DACs) with novel payloads.
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Previous Close:
$4.91
Open:
$4.92
24h Volume:
132.19K
Relative Volume:
0.28
Market Cap:
$401.01M
Revenue:
$16.72M
Net Income/Loss:
$-77.80M
P/E Ratio:
-4.7621
EPS:
-1.0573
Net Cash Flow:
$-43.78M
1W Performance:
+1.89%
1M Performance:
+31.84%
6M Performance:
+96.22%
1Y Performance:
+532.72%
1-Day Range:
Value
$4.84
$5.13
1-Week Range:
Value
$4.772
$5.69
52-Week Range:
Value
$0.75
$5.69

Prelude Therapeutics Inc Stock (PRLD) Company Profile

Name
Name
Prelude Therapeutics Inc
Name
Phone
(302) 467-1280
Name
Address
175 INNOVATION BOULEVARD, WILMINGTON
Name
Employee
79
Name
Twitter
Name
Next Earnings Date
2026-08-13
Name
Latest SEC Filings
Name
PRLD's Discussions on Twitter

Compare PRLD vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PRLD icon
PRLD
Prelude Therapeutics Inc
5.035 424.51M 16.72M -77.80M -43.78M -1.0573
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
528.50 126.07B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
647.30 65.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
926.00 57.70B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
313.72 40.19B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
188.90 39.82B 742.00K -1.37B -1.07B -7.0731

Prelude Therapeutics Inc Stock (PRLD) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-19-24 Upgrade H.C. Wainwright Neutral → Buy
Jun-20-24 Downgrade Barclays Equal Weight → Underweight
Mar-13-24 Initiated JMP Securities Mkt Outperform
Feb-20-24 Downgrade H.C. Wainwright Buy → Neutral
Dec-19-23 Downgrade Morgan Stanley Equal-Weight → Underweight
Nov-21-22 Downgrade BofA Securities Neutral → Underperform
Sep-09-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Jul-29-22 Initiated Jefferies Buy
Mar-15-22 Downgrade BofA Securities Buy → Neutral
Feb-28-22 Downgrade Barclays Overweight → Equal Weight
Oct-08-21 Upgrade Morgan Stanley Equal-Weight → Overweight
Jul-27-21 Upgrade BofA Securities Neutral → Buy
Apr-26-21 Initiated H.C. Wainwright Buy
Mar-09-21 Initiated Barclays Overweight
Nov-20-20 Downgrade BofA Securities Buy → Neutral
Oct-20-20 Initiated BofA Securities Buy
Oct-20-20 Initiated Goldman Neutral
Oct-20-20 Initiated Morgan Stanley Equal-Weight
View All

Prelude Therapeutics Inc Stock (PRLD) Latest News

pulisher
Jul 01, 2026

Citizens reiterates Prelude Therapeutics stock rating on IND filing By Investing.com - Investing.com Canada

Jul 01, 2026
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Jun 29, 2026

Prelude Therapeutics Incorporated(NasdaqGS:PRLD) added to Russell Small Cap Comp Growth Benchmark - marketscreener.com

Jun 29, 2026
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Jun 29, 2026

Prelude Therapeutics Incorporated(NasdaqGS:PRLD) added to Russell 2500 Growth Benchmark - marketscreener.com

Jun 29, 2026
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Jun 29, 2026

Prelude Therapeutics Incorporated(NasdaqGS: PRLD) added to Russell 2000 Index - marketscreener.com

Jun 29, 2026
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Jun 29, 2026

Prelude Therapeutics Incorporated(NasdaqGS:PRLD) added to Russell Microcap Growth Benchmark Index - marketscreener.com

Jun 29, 2026
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Jun 29, 2026

Prelude Therapeutics Incorporated(NasdaqGS:PRLD) added to Russell 2000 Growth Benchmark - marketscreener.com

Jun 29, 2026
pulisher
Jun 29, 2026

Prelude Therapeutics Incorporated(NasdaqGS:PRLD) added to Russell 3000E Growth Benchmark - marketscreener.com

Jun 29, 2026
pulisher
Jun 29, 2026

Prelude Therapeutics Incorporated(NasdaqGS: PRLD) added to Russell Microcap Index - marketscreener.com

Jun 29, 2026
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Jun 24, 2026

MapLight Therapeutics appoints two directors to board - Investing.com UK

Jun 24, 2026
pulisher
Jun 24, 2026

MapLight Therapeutics appoints two directors to board By Investing.com - Investing.com India

Jun 24, 2026
pulisher
Jun 24, 2026

Prelude Therapeutics Inc (PRLD) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jun 24, 2026
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Jun 21, 2026

Prelude Therapeutics (PRLD) Edges Lower as Stock Tests Key Support LevelADD Alert - dars.gov.et

Jun 21, 2026
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Jun 18, 2026

PRLD Technical Analysis | Trend, Signals & Chart Patterns - ChartMill

Jun 18, 2026
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Jun 18, 2026

Prelude Therapeutics Inc (PRLD) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jun 18, 2026
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Jun 17, 2026

Prelude Therapeutics Inc (PRLD) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jun 17, 2026
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Jun 17, 2026

Prelude Therapeutics Inc (PRLD) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Prelude Therapeutics Inc (PRLD) Revenue Breakdown: Business Segments, Regional Revenue & Profit Contribution - TradingKey

Jun 17, 2026
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Jun 17, 2026

Prelude Therapeutics Inc (PRLD) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Prelude Therapeutics Inc (PRLD) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

Jun 17, 2026
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Jun 17, 2026

Prelude Therapeutics Inc (PRLD) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jun 17, 2026
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Jun 17, 2026

Prelude Therapeutics Inc (PRLD) Institutional Confidence - TradingKey

Jun 17, 2026
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Jun 13, 2026

PRLD Q1 2026 Earnings: EPS Beat Drives Strong Stock ReactionEPS Growth Rate - newsline.com

Jun 13, 2026
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Jun 13, 2026

Market Sentiment Around Loss-Making Prelude Therapeutics Incorporated (NASDAQ:PRLD) - Moomoo

Jun 13, 2026
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Jun 11, 2026

PRLD Q1 2026 Earnings: Narrower Net Loss Beats EstimatesNegative Surprise Momentum - newsline.com

Jun 11, 2026
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Jun 10, 2026

[Form 4] Prelude Therapeutics Inc Insider Trading Activity - Stock Titan

Jun 10, 2026
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Jun 10, 2026

Director at Prelude Therapeutics (PRLD) awarded 38,000 stock options - Stock Titan

Jun 10, 2026
pulisher
Jun 10, 2026

Prelude Therapeutics (PRLD) director receives 38,000 stock options at $3.94 strike - Stock Titan

Jun 10, 2026
pulisher
Jun 10, 2026

Prelude Therapeutics (PRLD) shareholders back directors, auditor and say-on-pay - Stock Titan

Jun 10, 2026
pulisher
Jun 09, 2026

PRLD: All director, auditor, and executive compensation proposals were approved by shareholder vote - TradingView

Jun 09, 2026
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Jun 09, 2026

PRLD: All proposals passed, directors elected, auditor ratified, and no shareholder questions submitted - TradingView

Jun 09, 2026
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Jun 05, 2026

PRLD Stock Price, Quote & Chart | PRELUDE THERAPEUTICS INC (NASDAQ:PRLD) - ChartMill

Jun 05, 2026
pulisher
Jun 04, 2026

Prelude Therapeutics Rises Pre-Market With Focus on Two Cancer Drugs - Bez Kabli

Jun 04, 2026
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Jun 02, 2026

Prelude Therapeutics Reports Earnings and Advances Precision Oncology Pipeline - asatunews.co.id

Jun 02, 2026
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Jun 01, 2026

Prelude Therapeutics Reports First Quarter Financial Results and Pipeline Expansion - HarianBasis.co

Jun 01, 2026
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Jun 01, 2026

Goldman Sachs Initiates Coverage on Prelude Therapeutics: What It Could Mean for InvestorsEPS Growth Report - newsline.com

Jun 01, 2026
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May 31, 2026

Goldman Sachs Initiates Coverage of Prelude Therapeutics (PRLD) - Yahoo Finance

May 31, 2026
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May 28, 2026

Prelude Therapeutics Drops 5.5% as Biotech Sector Faces Headwinds – Key Support Levels in FocusBollinger Squeeze - The Legal Advocate

May 28, 2026
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May 28, 2026

PRLDPrelude Therapeutics Inc Stock Price and Quote - Finviz

May 28, 2026
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May 27, 2026

Prelude Therapeutics (PRLD) Extends Gains: Support Holds, Resistance in FocusFear Greed Index - The Legal Advocate

May 27, 2026
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May 27, 2026

PRLD Q1 2026 Earnings: Narrower-Than-Expected Loss as Clinical Pipeline AdvancesOne-Time Gain Impact - newsline.com

May 27, 2026
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May 26, 2026

Prelude Therapeutics Announces First Quarter 2026 Financial Results and Provides Corporate Update - geneonline.com

May 26, 2026
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May 24, 2026

Prelude Therapeutics: Current Cash Runway Into 2Q 2028 >PRLD - Moomoo

May 24, 2026
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May 19, 2026

New PROTACs reported in Prelude Therapeutics patent - BioWorld News

May 19, 2026
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May 17, 2026

Prelude Therapeutics Incorporated (NASDAQ:PRLD) Reported Earnings Last Week And Analysts Are Already Upgrading Their Estimates - Sahm

May 17, 2026
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May 16, 2026

Earnings Beat: Prelude Therapeutics Incorporated (NASDAQ:PRLD) Just Beat Analyst Forecasts, And Analysts Have Been Lifting Their Forecasts - Yahoo Finance

May 16, 2026
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May 15, 2026

Goldman Sachs initiates Prelude Therapeutics stock coverage as Early-Stage Biotech - Investing.com India

May 15, 2026
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May 14, 2026

Prelude Therapeutics (PRLD) price target increased by 11.49% to 7.01 - MSN

May 14, 2026
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May 13, 2026

Prelude Therapeutics (PRLD) Losses Narrow In Q1 2026 Challenging Bearish Narratives - Sahm

May 13, 2026
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May 12, 2026

TradingKey - TradingKey

May 12, 2026
pulisher
May 12, 2026

Jefferies raises Prelude Therapeutics stock price target on pipeline progress By Investing.com - Investing.com Australia

May 12, 2026
pulisher
May 12, 2026

Prelude (PRLD) Reports Progress on Strategic Initiatives and Cas - GuruFocus

May 12, 2026

Prelude Therapeutics Inc Stock (PRLD) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prelude Therapeutics Inc Stock (PRLD) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
ORBIMED ADVISORS LLC
Director
Apr 21 '26
Buy
4.44
2,815,315
12,499,999
11,808,945
$112.33
price up icon 0.72%
$35.01
price up icon 0.17%
$57.48
price down icon 0.50%
ONC ONC
$310.87
price up icon 4.52%
$83.25
price up icon 4.33%
$191.12
price up icon 0.74%
Cap:     |  Volume (24h):