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Prelude Therapeutics Inc stock is traded at $1.49, with a volume of 605.14K. It is up +6.79% in the last 24 hours and down -7.72% over the past month. Prelude Therapeutics Incorp is a clinical stage precision oncology company focused on discovering and developing small molecule therapies optimized to target the key driver mechanisms in cancers with high unmet needs. The company's pipeline includes four candidates currently in clinical development: PRT1419, a potent, selective inhibitor of MCL1; PRT2527, a potent and selective CDK9 inhibitor, PRT3645, a next-generation CDK4/6 inhibitor, and PRT3789 a first-in-class SMARCA2/BRM protein degrader.
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Previous Close:
$1.40
Open:
$1.42
24h Volume:
605.14K
Relative Volume:
0.48
Market Cap:
$93.67M
Revenue:
-
Net Income/Loss:
$-131.52M
P/E Ratio:
-0.8371
EPS:
-1.78
Net Cash Flow:
$-107.56M
1W Performance:
-11.01%
1M Performance:
-7.72%
6M Performance:
+68.70%
1Y Performance:
+55.05%
1-Day Range:
Value
$1.32
$1.5028
1-Week Range:
Value
$1.32
$1.70
52-Week Range:
Value
$0.6101
$4.22

Prelude Therapeutics Inc Stock (PRLD) Company Profile

Name
Name
Prelude Therapeutics Inc
Name
Phone
(302) 467-1280
Name
Address
175 INNOVATION BOULEVARD, WILMINGTON
Name
Employee
131
Name
Twitter
Name
Next Earnings Date
2024-10-30
Name
Latest SEC Filings
Name
PRLD's Discussions on Twitter

Compare PRLD with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
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PRLD
Prelude Therapeutics Inc
1.49 88.01M 0 -131.52M -107.56M -1.78
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VRTX
Vertex Pharmaceuticals Inc
429.04 107.58B 11.74B 3.68B 3.34B 14.19
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REGN
Regeneron Pharmaceuticals Inc
782.48 80.03B 14.25B 4.58B 3.88B 41.77
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ALNY
Alnylam Pharmaceuticals Inc
430.84 57.37B 3.21B 43.57M 221.36M 0.2405
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ARGX
Argen X Se Adr
907.72 55.83B 3.06B 1.28B 447.35M 19.67
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INSM
Insmed Inc
207.36 44.13B 447.02M -1.18B -906.14M -6.1812

Prelude Therapeutics Inc Stock (PRLD) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-19-24 Upgrade H.C. Wainwright Neutral → Buy
Jun-20-24 Downgrade Barclays Equal Weight → Underweight
Mar-13-24 Initiated JMP Securities Mkt Outperform
Feb-20-24 Downgrade H.C. Wainwright Buy → Neutral
Dec-19-23 Downgrade Morgan Stanley Equal-Weight → Underweight
Nov-21-22 Downgrade BofA Securities Neutral → Underperform
Sep-09-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Jul-29-22 Initiated Jefferies Buy
Mar-15-22 Downgrade BofA Securities Buy → Neutral
Feb-28-22 Downgrade Barclays Overweight → Equal Weight
Oct-08-21 Upgrade Morgan Stanley Equal-Weight → Overweight
Jul-27-21 Upgrade BofA Securities Neutral → Buy
Apr-26-21 Initiated H.C. Wainwright Buy
Mar-09-21 Initiated Barclays Overweight
Nov-20-20 Downgrade BofA Securities Buy → Neutral
Oct-20-20 Initiated BofA Securities Buy
Oct-20-20 Initiated Goldman Neutral
Oct-20-20 Initiated Morgan Stanley Equal-Weight
View All

Prelude Therapeutics Inc Stock (PRLD) Latest News

pulisher
07:08 AM

This trade activity should not be overlooked: Prelude Therapeutics Inc (PRLD) - Setenews

07:08 AM
pulisher
Nov 21, 2025

Prelude Therapeutics Experiences Revision in Its Stock Evaluation Amid Mixed Financial Trends - Markets Mojo

Nov 21, 2025
pulisher
Nov 20, 2025

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Prelude Therapeutics IncorporatedPRLD - PR Newswire

Nov 20, 2025
pulisher
Nov 19, 2025

Will Prelude Therapeutics Incorporated stock outperform Dow Jones indexJuly 2025 Sentiment & Smart Money Movement Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Is Prelude Therapeutics Incorporated stock supported by innovation pipeline2025 Volume Leaders & Free High Return Stock Watch Alerts - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

PRLD Investors Have Opportunity to Join Prelude Therapeutics Incorporated Fraud Investigation ... - Bakersfield.com

Nov 19, 2025
pulisher
Nov 19, 2025

PRLD Investors Have Opportunity to Join Prelude - GlobeNewswire

Nov 19, 2025
pulisher
Nov 19, 2025

What to do if you’re stuck in Prelude Therapeutics IncorporatedPortfolio Update Summary & Smart Investment Allocation Insights - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Is Prelude Therapeutics Incorporated stock ready for a breakoutJuly 2025 Sector Moves & Weekly Market Pulse Updates - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

What sentiment indicators say about Prelude Therapeutics Incorporated stock2025 Valuation Update & Safe Capital Growth Stock Tips - newser.com

Nov 19, 2025
pulisher
Nov 19, 2025

Prelude Advances Two Novel Cancer Programs as Cash Runway Extends Into 2027 - MyChesCo

Nov 19, 2025
pulisher
Nov 18, 2025

Order flow analysis tools used on Prelude Therapeutics IncorporatedJuly 2025 Sector Moves & Daily Volume Surge Signals - newser.com

Nov 18, 2025
pulisher
Nov 17, 2025

Can Prelude Therapeutics Incorporated stock hit analyst price targets2025 Geopolitical Influence & Fast Entry Momentum Trade Alerts - newser.com

Nov 17, 2025
pulisher
Nov 17, 2025

Real time alert setup for Prelude Therapeutics Incorporated performanceProduct Launch & Safe Entry Trade Signal Reports - newser.com

Nov 17, 2025
pulisher
Nov 17, 2025

Is Prelude Therapeutics Incorporated stock supported by strong fundamentalsJuly 2025 Market Mood & Weekly Breakout Stock Alerts - newser.com

Nov 17, 2025
pulisher
Nov 17, 2025

Century Therapeutics Unveils iPSC Beta Islet Program as Cash Runway Extends Into 2027 - MyChesCo

Nov 17, 2025
pulisher
Nov 17, 2025

Using flow based indicators on Prelude Therapeutics Incorporated2025 Market Sentiment & Fast Moving Trade Plans - newser.com

Nov 17, 2025
pulisher
Nov 17, 2025

Taking on analysts’ expectations and winning: Prelude Therapeutics Inc (PRLD) - Setenews

Nov 17, 2025
pulisher
Nov 17, 2025

Prelude Therapeutics’ Earnings Call Highlights Strategic Moves and Challenges - MSN

Nov 17, 2025
pulisher
Nov 16, 2025

Published on: 2025-11-16 22:10:23 - newser.com

Nov 16, 2025
pulisher
Nov 16, 2025

What institutional flow reveals about Prelude Therapeutics IncorporatedJuly 2025 Earnings & Safe Capital Growth Tips - newser.com

Nov 16, 2025
pulisher
Nov 16, 2025

Is Prelude Therapeutics Incorporated stock a defensive play in 2025Weekly Risk Summary & Daily Oversold Bounce Ideas - newser.com

Nov 16, 2025
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Nov 16, 2025

How to build a custom watchlist for Prelude Therapeutics IncorporatedJuly 2025 Fed Impact & Fast Entry High Yield Stock Tips - newser.com

Nov 16, 2025
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Nov 16, 2025

Pattern recognition hints at Prelude Therapeutics Incorporated upsideSwing Trade & Advanced Technical Analysis Signals - newser.com

Nov 16, 2025
pulisher
Nov 15, 2025

How moving averages guide Prelude Therapeutics Incorporated tradingBuy Signal & Weekly Breakout Watchlists - newser.com

Nov 15, 2025
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Nov 15, 2025

Can Prelude Therapeutics Incorporated stock sustain free cash flow growthJuly 2025 Price Swings & Community Trade Idea Sharing Platform - newser.com

Nov 15, 2025
pulisher
Nov 14, 2025

Volume spikes in Prelude Therapeutics Incorporated stock – what they meanMarket Performance Report & Daily Stock Momentum Reports - newser.com

Nov 14, 2025
pulisher
Nov 14, 2025

Prelude Therapeutics Incorporated (NASDAQ:PRLD) Q3 2025 Earnings Call Transcript - Insider Monkey

Nov 14, 2025
pulisher
Nov 14, 2025

Will Prelude Therapeutics Incorporated stock deliver shareholder valueTrade Exit Summary & AI Forecast for Swing Trade Picks - newser.com

Nov 14, 2025
pulisher
Nov 14, 2025

Prelude Therapeutics stock rating reiterated at Market Outperform by Citizens - Investing.com Canada

Nov 14, 2025
pulisher
Nov 14, 2025

Published on: 2025-11-14 02:04:28 - newser.com

Nov 14, 2025
pulisher
Nov 13, 2025

Prelude Therapeutics Advances Pipeline and Strengthens Financials - TipRanks

Nov 13, 2025
pulisher
Nov 12, 2025

Transcript : Prelude Therapeutics Incorporated, Q3 2025 Earnings Call, Nov 12, 2025 - MarketScreener

Nov 12, 2025
pulisher
Nov 12, 2025

Can Prelude Therapeutics Incorporated stock maintain operating margins2025 Key Lessons & Expert Approved Momentum Trade Ideas - newser.com

Nov 12, 2025
pulisher
Nov 12, 2025

Prelude Therapeutics Inc (PRLD) Q3 2025 Earnings Call Highlights: Strategic Partnerships and ... By GuruFocus - Investing.com Canada

Nov 12, 2025
pulisher
Nov 12, 2025

Prelude Therapeutics Inc (PRLD) Q3 2025 Earnings Call Highlights - GuruFocus

Nov 12, 2025
pulisher
Nov 12, 2025

Prelude Therapeutics Inc (PRLD) Q3 2025 Earnings Call Highlights: Strategic Partnerships and ... - Yahoo Finance

Nov 12, 2025
pulisher
Nov 12, 2025

Earnings call transcript: Prelude Therapeutics Q3 2025 sees stock steadiness By Investing.com - Investing.com South Africa

Nov 12, 2025

Prelude Therapeutics Inc Stock (PRLD) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Prelude Therapeutics Inc Stock (PRLD) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Vaddi Krishna
CEO
Mar 25 '25
Buy
0.69
675,000
467,438
1,999,296
Vaddi Krishna
CEO
Mar 21 '25
Buy
0.73
15,000
10,959
1,324,296
Vaddi Krishna
CEO
Mar 20 '25
Buy
0.73
5,416
3,950
1,309,296
Vaddi Krishna
CEO
Mar 14 '25
Buy
0.75
29,999
22,631
1,294,774
Vaddi Krishna
CEO
Mar 17 '25
Buy
0.75
9,106
6,829
1,303,880
Vaddi Krishna
CEO
Mar 13 '25
Buy
0.72
50,000
35,820
1,264,775
Vaddi Krishna
CEO
Mar 12 '25
Buy
0.71
47,500
33,744
1,214,775
Vaddi Krishna
CEO
Dec 31 '24
Buy
1.21
5,000
6,044
142,553
Vaddi Krishna
CEO
Dec 30 '24
Buy
1.20
10,000
12,000
137,553
Combs Andrew
Chief Chemistry Officer
Dec 23 '24
Buy
1.37
60,000
82,002
377,623
$39.55
price down icon 0.50%
$31.25
price up icon 1.41%
$106.07
price down icon 0.06%
$97.47
price up icon 0.91%
biotechnology ONC
$336.73
price up icon 1.36%
$207.67
price up icon 0.50%
Cap:     |  Volume (24h):