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Prelude Therapeutics Inc stock is traded at $2.14, with a volume of 98,258. It is up +3.94% in the last 24 hours and down -13.88% over the past month. Prelude Therapeutics Incorp is a clinical stage precision oncology company focused on discovering and developing small molecule therapies optimized to target the key driver mechanisms in cancers with high unmet needs. The company's pipeline includes four candidates currently in clinical development: PRT1419, a potent, selective inhibitor of MCL1; PRT2527, a potent and selective CDK9 inhibitor, PRT3645, a next-generation CDK4/6 inhibitor, and PRT3789 a first-in-class SMARCA2/BRM protein degrader.
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Previous Close:
$2.03
Open:
$2.02
24h Volume:
98,258
Relative Volume:
0.07
Market Cap:
$132.96M
Revenue:
-
Net Income/Loss:
$-131.52M
P/E Ratio:
-1.2022
EPS:
-1.78
Net Cash Flow:
$-107.56M
1W Performance:
+14.67%
1M Performance:
-13.88%
6M Performance:
+126.88%
1Y Performance:
+86.73%
1-Day Range:
Value
$1.99
$2.17
1-Week Range:
Value
$1.81
$2.30
52-Week Range:
Value
$0.6101
$4.22

Prelude Therapeutics Inc Stock (PRLD) Company Profile

Name
Name
Prelude Therapeutics Inc
Name
Phone
(302) 467-1280
Name
Address
175 INNOVATION BOULEVARD, WILMINGTON
Name
Employee
131
Name
Twitter
Name
Next Earnings Date
2024-10-30
Name
Latest SEC Filings
Name
PRLD's Discussions on Twitter

Compare PRLD with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
PRLD
Prelude Therapeutics Inc
2.115 127.62M 0 -131.52M -107.56M -1.78
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VRTX
Vertex Pharmaceuticals Inc
482.12 120.98B 11.74B 3.68B 3.34B 14.19
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REGN
Regeneron Pharmaceuticals Inc
766.66 80.15B 14.25B 4.58B 3.88B 41.77
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ARGX
Argen X Se Adr
869.32 51.56B 3.06B 1.28B 447.35M 19.67
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ALNY
Alnylam Pharmaceuticals Inc
361.98 47.74B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
ONC
Beone Medicines Ltd Adr
336.19 37.38B 4.98B 69.59M 525.67M 0.5197

Prelude Therapeutics Inc Stock (PRLD) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-19-24 Upgrade H.C. Wainwright Neutral → Buy
Jun-20-24 Downgrade Barclays Equal Weight → Underweight
Mar-13-24 Initiated JMP Securities Mkt Outperform
Feb-20-24 Downgrade H.C. Wainwright Buy → Neutral
Dec-19-23 Downgrade Morgan Stanley Equal-Weight → Underweight
Nov-21-22 Downgrade BofA Securities Neutral → Underperform
Sep-09-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Jul-29-22 Initiated Jefferies Buy
Mar-15-22 Downgrade BofA Securities Buy → Neutral
Feb-28-22 Downgrade Barclays Overweight → Equal Weight
Oct-08-21 Upgrade Morgan Stanley Equal-Weight → Overweight
Jul-27-21 Upgrade BofA Securities Neutral → Buy
Apr-26-21 Initiated H.C. Wainwright Buy
Mar-09-21 Initiated Barclays Overweight
Nov-20-20 Downgrade BofA Securities Buy → Neutral
Oct-20-20 Initiated BofA Securities Buy
Oct-20-20 Initiated Goldman Neutral
Oct-20-20 Initiated Morgan Stanley Equal-Weight
View All

Prelude Therapeutics Inc Stock (PRLD) Latest News

pulisher
Jan 26, 2026

Prelude Therapeutics’ PRT2527 Trial Completion: What Investors Should Watch in Hematologic Oncology - TipRanks

Jan 26, 2026
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Jan 26, 2026

Retail investors in Prelude Therapeutics Incorporated (NASDAQ:PRLD) are its biggest bettors, and their bets paid off as stock gained 12% last week - Yahoo Finance

Jan 26, 2026
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Jan 21, 2026

Aug Highlights: Does MAMO outperform in volatile markets2025 Support & Resistance & Free Weekly Watchlist of Top Performers - baoquankhu1.vn

Jan 21, 2026
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Jan 18, 2026

Prelude Therapeutics (NASDAQ:PRLD) Rating Lowered to Hold at Wall Street Zen - MarketBeat

Jan 18, 2026
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Jan 16, 2026

Aug Reactions: Can Prelude Therapeutics Incorporated outperform under higher oil pricesQuarterly Portfolio Summary & High Accuracy Swing Trade Signals - baoquankhu1.vn

Jan 16, 2026
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Jan 12, 2026

Market Review: Is Prelude Therapeutics Incorporated a cyclical or defensive stockMarket Volume Report & Community Verified Trade Signals - baoquankhu1.vn

Jan 12, 2026
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Jan 10, 2026

How Prelude Therapeutics Incorporated stock compares to industry benchmarksPortfolio Risk Report & Free Community Consensus Stock Picks - ulpravda.ru

Jan 10, 2026
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Jan 10, 2026

How Prelude Therapeutics Incorporated stock responds to policy changesMarket Activity Recap & Fast Entry High Yield Stock Tips - ulpravda.ru

Jan 10, 2026
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Jan 10, 2026

Prelude Therapeutics (NASDAQ:PRLD) Stock Rating Upgraded by Wall Street Zen - MarketBeat

Jan 10, 2026
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Jan 09, 2026

Prelude Therapeutics Inc Announces New Clinical Developments - TradingView — Track All Markets

Jan 09, 2026
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Jan 08, 2026

Aug Sentiment: How Prelude Therapeutics Incorporated stock responds to policy changesWeekly Investment Summary & Real-Time Market Sentiment Alerts - Улправда

Jan 08, 2026
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Jan 08, 2026

Will Prelude Therapeutics Incorporated stock reach all time highs in 2025Portfolio Update Report & Expert Verified Movement Alerts - Улправда

Jan 08, 2026
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Jan 08, 2026

Will Prelude Therapeutics Incorporated stock benefit from AI adoptionJuly 2025 Rallies & Free Real-Time Market Sentiment Alerts - Улправда

Jan 08, 2026
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Jan 08, 2026

Quarterly Trades: Is Prelude Therapeutics Incorporated stock positioned well for digital economyStop Loss & Free Daily Entry Point Trade Alerts - ulpravda.ru

Jan 08, 2026
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Jan 06, 2026

Prelude Therapeutics Reshapes Pipeline With Incyte Deal and Strategic Refocus - MSN

Jan 06, 2026
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Dec 31, 2025

Prelude Therapeutics Incorporated (NASDAQ:PRLD) Short Interest Up 28.5% in December - MarketBeat

Dec 31, 2025
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Dec 30, 2025

Bullish Prelude Therapeutics Insiders Rewarded As Their Investment Rises To US$2.75m - Sahm

Dec 30, 2025
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Dec 29, 2025

Prelude Therapeutics Incorporated's (NASDAQ:PRLD) Path To Profitability - Yahoo Finance

Dec 29, 2025
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Dec 25, 2025

Prelude Therapeutics (NASDAQ:PRLD) Stock Price Up 2.1%What's Next? - MarketBeat

Dec 25, 2025
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Dec 24, 2025

Is Prelude Therapeutics Stock Built to Withstand a Pullback? - Trefis

Dec 24, 2025
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Dec 20, 2025

What dividend safety score for Prelude Therapeutics Incorporated stock2025 Key Lessons & Risk Controlled Swing Alerts - Улправда

Dec 20, 2025
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Dec 19, 2025

Risk Analysis: What technical signals suggest for Prelude Therapeutics Incorporated stockForecast Cut & High Yield Stock Recommendations - Улправда

Dec 19, 2025
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Dec 19, 2025

Is Prelude Therapeutics Incorporated stock a buy before product launches2025 Price Action Summary & Technical Pattern Based Signals - Улправда

Dec 19, 2025
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Dec 19, 2025

Trend Report: Can Prelude Therapeutics Incorporated stock resist market sell offsJuly 2025 Setups & Free High Return Stock Watch Alerts - Улправда

Dec 19, 2025
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Dec 19, 2025

Is Prelude Therapeutics Incorporated stock positioned well for digital economyPrice Action & Technical Confirmation Alerts - DonanımHaber

Dec 19, 2025
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Dec 19, 2025

Is Prelude Therapeutics Incorporated stock overvalued by current metricsVolume Spike & Long-Term Investment Growth Plans - DonanımHaber

Dec 19, 2025
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Dec 19, 2025

Will Prelude Therapeutics Incorporated stock pay special dividends2025 Dividend Review & Daily Profit Maximizing Tips - DonanımHaber

Dec 19, 2025
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Dec 19, 2025

Can Prelude Therapeutics Incorporated stock sustain revenue growthJuly 2025 News Drivers & Fast Gain Swing Trade Alerts - DonanımHaber

Dec 19, 2025
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Dec 19, 2025

Why Prelude Therapeutics Incorporated stock attracts global investors2025 Dividend Review & Daily Profit Maximizing Tips - Bölüm Sonu Canavarı

Dec 19, 2025
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Dec 18, 2025

What technical signals suggest for Prelude Therapeutics Incorporated stockJuly 2025 EndofMonth & Weekly Return Optimization Plans - Улправда

Dec 18, 2025
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Dec 18, 2025

Is Prelude Therapeutics Incorporated stock a buy for dividend growthJuly 2025 Closing Moves & Weekly Top Gainers Trade List - Улправда

Dec 18, 2025
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Dec 18, 2025

Prelude Therapeutics Earnings Notes - Trefis

Dec 18, 2025
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Dec 16, 2025

Cancer Drug Developers Secure Regulatory Clarity as FDA Reshapes Approval Standards - GlobeNewswire

Dec 16, 2025
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Dec 10, 2025

Prelude Therapeutics divulges new JAK2 inhibitors - BioWorld MedTech

Dec 10, 2025
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Dec 10, 2025

It makes sense and dollars to buy Prelude Therapeutics Inc (PRLD) stock - setenews.com

Dec 10, 2025
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Dec 09, 2025

Prelude Therapeutics presents data at 2025 ASH meeting from MPN programs - MSN

Dec 09, 2025
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Dec 08, 2025

Prelude Therapeutics stock rating reiterated at Market Outperform by Citizens - Investing.com Canada

Dec 08, 2025
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Dec 07, 2025

Prelude Therapeutics (PRLD) Reveals Promising Preclinical Data a - GuruFocus

Dec 07, 2025
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Dec 06, 2025

Prelude Therapeutics Unveils Promising Preclinical Data for JAK2V617F-selective JH2 Inhibitor and mCALR-targeted Degrader Antibody Conjugate at ASH 2025 - Quiver Quantitative

Dec 06, 2025
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Dec 06, 2025

Prelude Therapeutics Presents Data at the 2025 ASH Annual - GlobeNewswire

Dec 06, 2025
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Dec 06, 2025

Prelude Therapeutics (Nasdaq: PRLD) details MPN pipeline at 2025 ASH, eyes 2026 IND - Stock Titan

Dec 06, 2025
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Dec 04, 2025

What insider trading reveals about Prelude Therapeutics Incorporated stockShort Setup & Daily Volume Surge Trade Alerts - Newser

Dec 04, 2025
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Dec 01, 2025

Penny Stocks To Consider In December 2025 - simplywall.st

Dec 01, 2025
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Nov 28, 2025

VIX Spike: How Prelude Therapeutics Incorporated stock compares to industry benchmarksJuly 2025 Decliners & Growth Focused Stock Pick Reports - Bộ Nội Vụ

Nov 28, 2025
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Nov 27, 2025

Growth Report: What dividend safety score for Prelude Therapeutics Incorporated stockJuly 2025 Big Picture & Daily Volume Surge Signals - moha.gov.vn

Nov 27, 2025
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Nov 26, 2025

PRLD Investors Have Opportunity to Join Prelude - GlobeNewswire

Nov 26, 2025
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Nov 25, 2025

This trade activity should not be overlooked: Prelude Therapeutics Inc (PRLD) - Setenews

Nov 25, 2025
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Nov 24, 2025

Beat the Market the Zacks Way: Goldman Sachs, Micron, Prelude in Focus - Zacks Investment Research

Nov 24, 2025
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Nov 21, 2025

Prelude Therapeutics Experiences Revision in Its Stock Evaluation Amid Mixed Financial Trends - Markets Mojo

Nov 21, 2025
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Nov 20, 2025

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Prelude Therapeutics IncorporatedPRLD - PR Newswire

Nov 20, 2025
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Nov 19, 2025

Will Prelude Therapeutics Incorporated stock outperform Dow Jones indexJuly 2025 Sentiment & Smart Money Movement Alerts - newser.com

Nov 19, 2025

Prelude Therapeutics Inc Stock (PRLD) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$100.07
price up icon 2.34%
$103.97
price up icon 1.39%
$34.40
price up icon 2.76%
$120.06
price up icon 1.64%
$165.28
price up icon 3.45%
biotechnology ONC
$336.10
price down icon 0.50%
Cap:     |  Volume (24h):