67.71
price down icon1.67%   -1.15
pre-market  Pre-market:  68.60   0.89   +1.31%
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Oruka Therapeutics Inc stock is traded at $67.71, with a volume of 816.20K. It is down -1.67% in the last 24 hours and up +9.33% over the past month. Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
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Previous Close:
$68.86
Open:
$69.05
24h Volume:
816.20K
Relative Volume:
0.53
Market Cap:
$4.08B
Revenue:
-
Net Income/Loss:
$-116.25M
P/E Ratio:
-28.32
EPS:
-2.3912
Net Cash Flow:
$-91.19M
1W Performance:
+1.17%
1M Performance:
+9.33%
6M Performance:
+133.97%
1Y Performance:
+444.73%
1-Day Range:
Value
$66.68
$69.65
1-Week Range:
Value
$63.95
$71.72
52-Week Range:
Value
$10.77
$91.00

Oruka Therapeutics Inc Stock (ORKA) Company Profile

Name
Name
Oruka Therapeutics Inc
Name
Phone
650-606-7910
Name
Address
855 OAK GROVE AVE., MENLO PARK
Name
Employee
68
Name
Twitter
Name
Next Earnings Date
2026-05-13
Name
Latest SEC Filings
Name
ORKA's Discussions on Twitter

Compare ORKA vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
ORKA icon
ORKA
Oruka Therapeutics Inc
67.71 4.15B 0 -116.25M -91.19M -2.3912
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
453.17 114.33B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
614.73 64.47B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
878.49 54.99B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
281.90 38.42B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
156.58 34.03B 742.00K -1.37B -1.07B -7.0731

Oruka Therapeutics Inc Stock (ORKA) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-18-25 Initiated Piper Sandler Overweight
Nov-13-25 Initiated Jefferies Buy
Oct-27-25 Initiated Guggenheim Buy
Oct-13-25 Initiated Barclays Overweight
May-22-25 Initiated BTIG Research Buy
Feb-04-25 Initiated Wolfe Research Outperform
Oct-11-24 Initiated Stifel Buy
Oct-07-24 Initiated H.C. Wainwright Buy
Sep-17-24 Initiated Leerink Partners Outperform
Sep-16-24 Initiated TD Cowen Buy
Sep-13-24 Initiated Jefferies Buy
Feb-27-18 Initiated Ascendiant Capital Markets Buy
Oct-09-13 Initiated Dawson James Buy
View All

Oruka Therapeutics Inc Stock (ORKA) Latest News

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Jun 15, 2026

Oruka Therapeutics COO Laura Sandler sells $41,814 in ORKA shares - Investing.com

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics general counsel Paul Quinlan sells $51,082 in stock - Investing.com

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics CMO Joana Goncalves sells $550,606 in stock - Investing.com

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics SVP of finance Arjun Agarwal sells $687k in stock By Investing.com - Investing.com India

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics general counsel Paul Quinlan sells $51,082 in stock By Investing.com - Investing.com India

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) SVP exercises options, sells shares to cover tax obligations - Stock Titan

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) CMO sells shares and exercises stock options - Stock Titan

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) CEO has 1,729 shares sold for RSU tax withholding - Stock Titan

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) COO sells 600 shares to cover taxes - Stock Titan

Jun 15, 2026
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Jun 15, 2026

Oruka Therapeutics (ORKA) counsel sells 733 shares in tax sell-to-cover - Stock Titan

Jun 15, 2026
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Jun 14, 2026

Wall Street Analysts Believe Oruka Therapeutics, Inc. (ORKA) Could Rally 111.13%: Here's is How to Trade - MSN

Jun 14, 2026
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Jun 12, 2026

Insider Sell: Carl Dambkowski Sells 35,000 Shares of Oruka Thera - GuruFocus

Jun 12, 2026
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Jun 12, 2026

Certain Warrants of Oruka Therapeutics, Inc. are subject to a Lock-Up Agreement Ending on 13-JUN-2026. - marketscreener.com

Jun 12, 2026
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Jun 12, 2026

Certain Series B Preferred Stock of Oruka Therapeutics, Inc. are subject to a Lock-Up Agreement Ending on 13-JUN-2026. - marketscreener.com

Jun 12, 2026
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Jun 12, 2026

Oruka Therapeutics (ORKA) director sells 35,000 shares under Rule 10b5-1 plan - Stock Titan

Jun 12, 2026
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Jun 12, 2026

Oruka Therapeutics, Inc. (ORKA) upgraded to buy: What does it mean for the stock? - MSN

Jun 12, 2026
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Jun 12, 2026

Oruka Therapeutics, Inc. (ORKA) Upgraded to Buy: What Does It Mean for the Stock? - Yahoo Finance

Jun 12, 2026
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Jun 11, 2026

ORKA (NASDAQ: ORKA) notice to sell 35,000 shares; insider sold 105,000 - Stock Titan

Jun 11, 2026
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Jun 11, 2026

ORKA Stock Is Soaring After Psoriasis Trial Results — Here's Why BTIG Hiked Its Price Target By 94% - Stocktwits

Jun 11, 2026
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Jun 10, 2026

ORKA News | ORUKA THERAPEUTICS INC (NASDAQ:ORKA) - ChartMill

Jun 10, 2026
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Jun 07, 2026

Basic earnings per share (basic EPS) of Oruka Therapeutics, Inc. – XETR:HQ1 - TradingView

Jun 07, 2026
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Jun 07, 2026

Is Oruka’s Broadened IL-23 License Reshaping Optionality And Altering The Investment Case For Oruka Therapeutics (ORKA)? - simplywall.st

Jun 07, 2026
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Jun 06, 2026

Gross margin % of Oruka Therapeutics, Inc. – XETR:HQ1 - TradingView

Jun 06, 2026
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Jun 06, 2026

Asset turnover of Oruka Therapeutics, Inc. – XETR:HQ1 - TradingView

Jun 06, 2026
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Jun 06, 2026

Oruka Therapeutics, Inc. Statistics – XETR:HQ1 - TradingView

Jun 06, 2026
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Jun 06, 2026

Oruka Therapeutics, Inc. Income Statement – XETR:HQ1 - TradingView

Jun 06, 2026
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Jun 06, 2026

ETFs Investing in Oruka Therapeutics, Inc. Stocks - TradingView

Jun 06, 2026
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Jun 05, 2026

Halozyme licenses Hypercon technology to Oruka for psoriasis drug - Investing.com

Jun 05, 2026
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Jun 04, 2026

Oruka Therapeutics Shareholders Back Governance and Executive Pay - TipRanks

Jun 04, 2026
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Jun 04, 2026

Oruka Therapeutics (ORKA) investors approve directors, auditor and executive pay - Stock Titan

Jun 04, 2026
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Jun 04, 2026

H.C. Wainwright reiterates Oruka Therapeutics stock rating at buy By Investing.com - Investing.com South Africa

Jun 04, 2026
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Jun 03, 2026

Oruka Therapeutics (ORKA) director awarded 9,136 stock options with 2036 expiry - Stock Titan

Jun 03, 2026
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Jun 03, 2026

Oruka Therapeutics (ORKA) grants director 9,136 stock options - Stock Titan

Jun 03, 2026
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Jun 03, 2026

Director at Oruka Therapeutics (ORKA) receives 9,136 stock options award - Stock Titan

Jun 03, 2026
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Jun 03, 2026

Oruka Therapeutics (ORKA) director granted 9,136 stock options - Stock Titan

Jun 03, 2026
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Jun 03, 2026

Oruka Therapeutics (NASDAQ: ORKA) grants 9,136-share option to Fairmount-managed funds - Stock Titan

Jun 03, 2026
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Jun 03, 2026

H.C. Wainwright reiterates Oruka Therapeutics stock rating at buy - Investing.com

Jun 03, 2026
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Jun 02, 2026

Oruka Therapeutics stock rating reaffirmed by Piper Sandler at Overweight - Investing.com Canada

Jun 02, 2026
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Jun 02, 2026

UBS Maintains Oruka Therapeutics(ORKA.US) With Buy Rating, Maintains Target Price $100 - Moomoo

Jun 02, 2026
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Jun 01, 2026

Oruka Therapeutics Expands IL-23 License, Adds Dosing Limits - TipRanks

Jun 01, 2026
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Jun 01, 2026

Oruka Therapeutics (NASDAQ: ORKA) widens IL-23 rights but delays IBD dosing - Stock Titan

Jun 01, 2026
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May 31, 2026

An Oruka Therapeutics (ORKA) Insider Sold 105,000 Shares Worth $6.2 Million - Yahoo Finance

May 31, 2026
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May 31, 2026

An Oruka Therapeutics (ORKA) Insider Sold 105,000 Shares Worth $6.2 Million - The Motley Fool

May 31, 2026
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May 31, 2026

Number of shareholders of Oruka Therapeutics, Inc. – NASDAQ:ORKA - TradingView

May 31, 2026
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May 31, 2026

Number of shareholders of Oruka Therapeutics, Inc. – SWB:HQ1 - TradingView

May 31, 2026
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May 30, 2026

Oruka Insider Sells $463K in Stock as Shares Skyrocket 650%, but Here's What Matters for Investors - AOL.com

May 30, 2026
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May 28, 2026

Oruka Therapeutics to Present at the 2026 Jefferies Global Healthcare Conference - The Manila Times

May 28, 2026
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May 24, 2026

Encouraging ORKA-001 Psoriasis Data and Upsized Offering Could Be A Game Changer For Oruka Therapeutics (ORKA) - Sahm

May 24, 2026
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May 23, 2026

Oruka Therapeutics(ORKA.US) Director Sells US$6.19 Million in Common Stock - Moomoo

May 23, 2026
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May 23, 2026

Wedbush Adjusts Price Target on Oruka Therapeutics to $165 From $85, Maintains Outperform Rating - Moomoo

May 23, 2026
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May 23, 2026

Oruka Therapeutics director Carl Dambkowski sells $6.19m in stock - Investing.com India

May 23, 2026

Oruka Therapeutics Inc Stock (ORKA) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Oruka Therapeutics Inc Stock (ORKA) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Agarwal Arjun
Senior Vice President, Finance
Jun 12 '26
Sale
69.72
9,459
659,508
17,294
Agarwal Arjun
Senior Vice President, Finance
Jun 15 '26
Sale
69.69
395
27,528
16,899
Goncalves Joana
Chief Medical Officer
Jun 15 '26
Option Exercise
7.32
7,000
51,240
40,665
Goncalves Joana
Chief Medical Officer
Jun 15 '26
Sale
69.28
7,947
550,607
32,718
Klein Lawrence Otto
Chief Executive Officer
Jun 15 '26
Sale
69.69
1,729
120,494
925,580
Sandler Laura Lee
Chief Operating Officer
Jun 15 '26
Sale
69.69
600
41,814
236,384
Quinlan Paul T
General Counsel
Jun 15 '26
Sale
69.69
733
51,083
31,034
Dambkowski Carl
Director
Jun 11 '26
Sale
70.13
22,417
1,572,201
51,326
Dambkowski Carl
Director
Jun 12 '26
Sale
70.11
12,583
882,182
38,743
$30.41
price up icon 1.27%
$55.40
price up icon 6.27%
$89.50
price down icon 1.43%
$54.21
price down icon 0.11%
ONC ONC
$263.92
price down icon 1.60%
$156.58
price down icon 2.17%
Cap:     |  Volume (24h):