3.97
price down icon3.17%   -0.13
after-market After Hours: 3.99 0.02 +0.50%
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Orchestra Biomed Holdings Inc stock is traded at $3.97, with a volume of 157.04K. It is down -3.17% in the last 24 hours and up +6.72% over the past month. Orchestra BioMed Holdings Inc is a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships with medical device companies. The company's flagship product candidates are Atrioventricular Interval Modulation Therapy (AVIM Therapy) for the treatment of hypertension, the risk factor for death, and Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the cause of mortality. It has one reportable segment, which consists of the development of clinical and preclinical product candidates through risk-reward sharing partnerships with medical device companies.
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Previous Close:
$4.10
Open:
$4.12
24h Volume:
157.04K
Relative Volume:
0.72
Market Cap:
$237.73M
Revenue:
$32.72M
Net Income/Loss:
$-54.64M
P/E Ratio:
-3.5204
EPS:
-1.1277
Net Cash Flow:
$-55.08M
1W Performance:
+0.51%
1M Performance:
+6.72%
6M Performance:
-7.67%
1Y Performance:
+28.48%
1-Day Range:
Value
$3.915
$4.14
1-Week Range:
Value
$3.915
$4.17
52-Week Range:
Value
$2.20
$5.424

Orchestra Biomed Holdings Inc Stock (OBIO) Company Profile

Name
Name
Orchestra Biomed Holdings Inc
Name
Phone
646-343-9298
Name
Address
150 UNION SQUARE DRIVE, NEW HOPE
Name
Employee
86
Name
Twitter
Name
Next Earnings Date
2026-05-11
Name
Latest SEC Filings
Name
OBIO's Discussions on Twitter

Compare OBIO vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
OBIO icon
OBIO
Orchestra Biomed Holdings Inc
3.97 245.51M 32.72M -54.64M -55.08M -1.1277
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
450.46 112.92B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
614.98 64.18B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
884.20 55.57B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
287.80 37.76B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
160.06 32.71B 742.00K -1.37B -1.07B -7.0731

Orchestra Biomed Holdings Inc Stock (OBIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-10-25 Initiated TD Cowen Buy
Aug-20-25 Downgrade BTIG Research Buy → Neutral
Mar-20-25 Initiated BTIG Research Buy
Jan-02-25 Initiated Barclays Overweight
Aug-22-24 Initiated H.C. Wainwright Buy
Jul-25-24 Initiated B. Riley Securities Buy
Jan-19-24 Initiated Jefferies Buy
Feb-24-23 Initiated Piper Sandler Overweight
Feb-07-23 Initiated Chardan Capital Markets Buy
View All

Orchestra Biomed Holdings Inc Stock (OBIO) Latest News

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Jun 13, 2026

OBIO Q1 2026 Earnings: Narrower-than-Expected Loss as Clinical Pipeline AdvancesRevenue Recognition Risk - newsline.com

Jun 13, 2026
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Jun 12, 2026

Orchestra BioMed (OBIO) Edges Higher, Testing Key Resistance Zone on Modest VolumeLow Beta Factor - newsline.com

Jun 12, 2026
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Jun 12, 2026

Orchestra BioMed (NASDAQ: OBIO) CFO has shares withheld to cover RSU tax obligations - Stock Titan

Jun 12, 2026
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Jun 12, 2026

Orchestra BioMed (OBIO) insider uses 6,566 shares to cover RSU taxes - Stock Titan

Jun 12, 2026
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Jun 09, 2026

Orchestra BioMed Grants Equity Awards to New Employees - MyChesCo

Jun 09, 2026
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Jun 08, 2026

Number of shareholders of Orchestra BioMed Holdings, Inc. – NASDAQ:OBIO - TradingView

Jun 08, 2026
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Jun 05, 2026

Orchestra BioMed Holdings (OBIO) Slips 2.26% as Shares Test Support Near $3.70Chart Pattern Alerts - newsline.com

Jun 05, 2026
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Jun 05, 2026

Orchestra BioMed receives $20 million from Medtronic - Investing.com

Jun 05, 2026
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Jun 04, 2026

OBIO: Upcoming BackBeat and Virtue trial milestones signal strong growth and partnership-driven value - TradingView

Jun 04, 2026
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Jun 03, 2026

12 Health Care Stocks Moving In Wednesday's After-Market Session - Benzinga

Jun 03, 2026
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Jun 03, 2026

Insider Sell Alert: Darren Sherman Sells Shares of Orchestra Bio - GuruFocus

Jun 03, 2026
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Jun 02, 2026

Insider Sell Alert: Darren Sherman Sells Shares of Orchestra BioMed Holdings Inc (OBIO) - GuruFocus

Jun 02, 2026
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Jun 02, 2026

Orchestra BioMed (OBIO) director adds 5,000 shares in open-market buy - Stock Titan

Jun 02, 2026
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Jun 02, 2026

Orchestra BioMed (OBIO) director Darren Sherman sells 15,000 shares under 10b5-1 plan - Stock Titan

Jun 02, 2026
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Jun 02, 2026

Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - Caledonian Record

Jun 02, 2026
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Jun 01, 2026

Affiliate sale notice: OBIO (NASDAQ: OBIO) proposes sale of 15,000 shares - Stock Titan

Jun 01, 2026
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May 31, 2026

OBIO Q1 2026 Earnings: Narrower-Than-Expected Loss as Company Advances PipelineAnnual Report - newsline.com

May 31, 2026
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May 30, 2026

Orchestra BioMed Holdings (OBIO) Slides 1.76% as Shares Test Key Support LevelsIron Condor Alert - thelegaladvocate.com

May 30, 2026
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May 30, 2026

OBIO Q1 2026 Earnings: Narrower-Than-Expected Loss Fuels Optimism Amid Pre-Revenue StageHigh Growth Earnings - newsline.com

May 30, 2026
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May 29, 2026

Orchestra BioMed (OBIO) CFO has 3,076 RSU shares withheld for taxes - Stock Titan

May 29, 2026
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May 29, 2026

Orchestra BioMed (OBIO) insider reports RSU tax-withholding of 4,925 shares - Stock Titan

May 29, 2026
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May 29, 2026

OBIO Q1 2026 Earnings: Loss Narrows More Than Expected, Stock Modestly DeclinesAnnual Earnings Summary - newsline.com

May 29, 2026
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May 28, 2026

Orchestra BioMed (OBIO) Edges Higher: Navigating Key Support and Resistance LevelsPullback Trade - The Legal Advocate

May 28, 2026
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May 28, 2026

OBIO Q1 2026 Earnings: EPS Beat Narrowed Losses, But No Revenue YetStrong Earnings Momentum - The Legal Advocate

May 28, 2026
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May 25, 2026

OBIO Q1 2026 Earnings: Narrower-than-Expected Loss Highlights Cost Discipline in Pre-Revenue Phase - Newser

May 25, 2026
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May 25, 2026

Orchestra BioMed Holdings (OBIO) Slips Slightly as Stock Hovers Near SupportBreakaway Gap - newsline.com

May 25, 2026
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May 22, 2026

OBIO Q1 2026 Earnings: Narrowed Loss as EPS Surpasses Estimates; Stock Posts Modest DeclineLong-Term Guidance - Newser

May 22, 2026
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May 22, 2026

Orchestra BioMed Advances FDA Path for Hypertension Device - MyChesCo

May 22, 2026
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May 22, 2026

Orchestra BioMed Targets 2027 Data for Hypertension Trial - MyChesCo

May 22, 2026
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May 21, 2026

Favourable Signals For Orchestra BioMed Holdings: Numerous Insiders Acquired Stock - Yahoo Finance

May 21, 2026
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May 20, 2026

Orchestra BioMed director Jason buys $2,493 in stock - Investing.com UK

May 20, 2026
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May 20, 2026

Orchestra BioMed director Jason buys $2,493 in stock By Investing.com - Investing.com Canada

May 20, 2026
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May 20, 2026

Orchestra BioMed (OBIO) director adds 665 shares in open-market buy - Stock Titan

May 20, 2026
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May 20, 2026

Orchestra BioMed Holdings (OBIO) price target increased by 11.30% to 12.68 - MSN

May 20, 2026
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May 19, 2026

Orchestra BioMed CEO David Hochman buys $18,850 in company stock By Investing.com - Investing.com Nigeria

May 19, 2026
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May 19, 2026

Orchestra BioMed director Aryeh Jason buys $34,986 in stock By Investing.com - Investing.com Nigeria

May 19, 2026
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May 19, 2026

Orchestra BioMed director Aryeh Jason buys $34,986 in stock - Investing.com India

May 19, 2026
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May 19, 2026

Orchestra BioMed to Participate in the Jefferies Global Healthcare Conference - GlobeNewswire

May 19, 2026
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May 19, 2026

Orchestra BioMed CEO David Hochman buys $18,850 in company stock - Investing.com

May 19, 2026
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May 19, 2026

Director at Orchestra BioMed (OBIO) buys 8,971 shares in open market - Stock Titan

May 19, 2026
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May 19, 2026

B. Riley Cuts Price Target on Orchestra BioMed Holdings to $10 From $12, Keeps Buy Rating - marketscreener.com

May 19, 2026
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May 18, 2026

Orchestra BioMed director Fain buys $82,600 in shares By Investing.com - Investing.com South Africa

May 18, 2026
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May 18, 2026

Orchestra BioMed director Fain buys $82,600 in shares - Investing.com UK

May 18, 2026

Orchestra Biomed Holdings Inc Stock (OBIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$97.46
price down icon 0.40%
$30.03
price down icon 0.03%
$90.80
price up icon 0.29%
$54.27
price down icon 1.09%
ONC ONC
$268.20
price up icon 1.41%
$160.06
price up icon 4.02%
Cap:     |  Volume (24h):