3.97

0.50% -0.02

Pre-market: 4.05 0.08 +2.02%

Orchestra Biomed Holdings Inc (OBIO)

Overview News Price History Discussions Forecast

Orchestra Biomed Holdings Inc stock is traded at $3.97, with a volume of 158.66K. It is down -0.50% in the last 24 hours and down -8.53% over the past month. Orchestra BioMed Holdings Inc is a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships with medical device companies. The company's flagship product candidates are Atrioventricular Interval Modulation Therapy (AVIM Therapy) for the treatment of hypertension, the risk factor for death, and Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the cause of mortality. It has one reportable segment, which consists of the development of clinical and preclinical product candidates through risk-reward sharing partnerships with medical device companies.

Previous Close:

$3.99

Open:

$4.06

24h Volume:

158.66K

Relative Volume:

0.77

Market Cap:

$232.33M

Revenue:

$33.48M

Net Income/Loss:

$-52.70M

P/E Ratio:

-3.0801

EPS:

-1.2889

Net Cash Flow:

$-49.45M

1W Performance:

-3.87%

1M Performance:

-8.53%

6M Performance:

+1.79%

1Y Performance:

+44.36%

1-Day Range:

$3.935

$4.06

1-Week Range:

$3.775

$4.22

52-Week Range:

$2.20

$5.424

Orchestra Biomed Holdings Inc Stock (OBIO) Company Profile

Name

Orchestra Biomed Holdings Inc

Sector

Healthcare (1112)

Industry

Biotechnology (622)

Phone

646-343-9298

Address

150 UNION SQUARE DRIVE, NEW HOPE

Employee

Twitter

Next Earnings Date

2026-05-11

Latest SEC Filings

OBIO's Discussions on Twitter

Compare OBIO vs VRTX, REGN, ARGX, ALNY, ONC

Stocks	Price	Market Cap	Revenue	Net Income	Cash Flow	EPS
OBIO Orchestra Biomed Holdings Inc	3.97	232.33M	33.48M	-52.70M	-49.45M	-1.2889
VRTX Vertex Pharmaceuticals Inc	423.92	107.83B	12.07B	3.95B	3.19B	15.33
REGN Regeneron Pharmaceuticals Inc	701.42	73.54B	14.92B	4.42B	3.79B	41.04
ARGX Argen X Se Adr	783.50	48.72B	4.16B	1.29B	734.26M	19.58
ALNY Alnylam Pharmaceuticals Inc	296.11	39.51B	3.71B	313.75M	465.38M	2.2571
ONC Beone Medicines Ltd Adr	293.86	32.66B	5.36B	287.73M	924.18M	2.5229

Orchestra Biomed Holdings Inc Stock (OBIO) Upgrades & Downgrades

Date	Action	Analyst	Rating Change
Dec-10-25	Initiated	TD Cowen	Buy
Aug-20-25	Downgrade	BTIG Research	Buy → Neutral
Mar-20-25	Initiated	BTIG Research	Buy
Jan-02-25	Initiated	Barclays	Overweight
Aug-22-24	Initiated	H.C. Wainwright	Buy
Jul-25-24	Initiated	B. Riley Securities	Buy
Jan-19-24	Initiated	Jefferies	Buy
Feb-24-23	Initiated	Piper Sandler	Overweight
Feb-07-23	Initiated	Chardan Capital Markets	Buy

View All

Orchestra Biomed Holdings Inc Stock (OBIO) Latest News

Apr 30, 2026

FDA Grants Orchestra BioMed Additional Breakthrough Device Designation for AVIM Therapy - Investing News Network

Apr 30, 2026

Apr 29, 2026

Orchestra BioMed: RTW funds sell $132 in stock By Investing.com - Investing.com Canada

Apr 29, 2026

Orchestra BioMed: RTW funds sell $132 in stock - Investing.com

Apr 29, 2026

Orchestra BioMed (OBIO) stake rises to 19.2% after RTW warrant exercise - Stock Titan

Apr 29, 2026

RTW funds exercise 1.25M Orchestra BioMed (NASDAQ: OBIO) pre-funded warrants - Stock Titan

Apr 29, 2026

Orchestra BioMed (NASDAQ: OBIO) seeks ESPP, director votes at 2026 meeting - Stock Titan

Apr 29, 2026

Apr 27, 2026

BTIG Downgrades Orchestra BioMed Holdings (OBIO) - MSN

Apr 27, 2026

Orchestra BioMed Holdings (OBIO) price target decreased by 11.17% to 11.39 - MSN

Apr 27, 2026

Apr 24, 2026

Orchestra BioMed launches public offering; shares down 16% - MSN

Apr 24, 2026

Apr 23, 2026

Orchestra BioMed to Present AVIM Therapy Clinical and Mechanistic Data at HRS 2026 - Investing News Network

Apr 23, 2026

Orchestra BioMed Reports Positive Results from MODERATO II Trial for Atrioventricular Interval Modulation Therapy in Hypertension Management - Quiver Quantitative

Apr 23, 2026

Study data showed a 13.2 mmHg drop in systolic blood pressure with AVIM - Stock Titan

Apr 23, 2026

Apr 17, 2026

Orchestra BioMed Holdings, Inc. (NASDAQ:OBIO) Sees Large Growth in Short Interest - MarketBeat

Apr 17, 2026

Apr 13, 2026

Portfolio Update: Will Orchestra BioMed Holdings Inc benefit from geopolitical trends2026 Reactions & Smart Allocation Stock Tips - baoquankhu1.vn

Apr 13, 2026

If You Invested $1,000 in Orchestra BioMed Holdings Inc (OBIO) - Stock Titan

Apr 13, 2026

Orchestra BioMed Holdings, Inc. (NASDAQ:OBIO) Given Consensus Recommendation of "Moderate Buy" by Brokerages - MarketBeat

Apr 13, 2026

Gains Report: How much upside does Orchestra BioMed Holdings Inc haveMarket Growth Report & Real-Time Market Sentiment Reports - baoquankhu1.vn

Apr 13, 2026

Apr 11, 2026

OBIO Options Volatility — NASDAQ:OBIO - TradingView

Apr 11, 2026

OBIO Options Chain — NASDAQ:OBIO - TradingView

Apr 11, 2026

Apr 10, 2026

Is Orchestra (OBIO) Stock Ready to Drop | Price at $4.18, Down 1.18%Real Time Stock Idea Network - Cổng thông tin điện tử tỉnh Lào Cai

Apr 10, 2026

Apr 09, 2026

How sensitive is Orchestra BioMed Holdings Inc to inflation2026 Market Outlook & Verified High Yield Trade Plans - baoquankhu1.vn

Apr 09, 2026

Apr 06, 2026

Orchestra BioMed : April 2026 Corporate Presentation - marketscreener.com

Apr 06, 2026

Apr 02, 2026

Orchestra BioMed Holdings (OBIO) Stock Price Prediction: Today, Tomorrow, Next Week - Traders Union

Apr 02, 2026

Orchestra Biomed Holdings Inc (NASDAQ:OBIO) Fits the Minervini High-Growth Momentum Template - ChartMill

Apr 02, 2026

Mar 30, 2026

Aug Fed Impact: What is Orchestra BioMed Holdings Incs 5 year growth outlook - baoquankhu1.vn

Mar 30, 2026

Activity Recap: Does Orchestra BioMed Holdings Inc outperform in volatile markets2026 Market WrapUp & Fast Gain Swing Trade Alerts - baoquankhu1.vn

Mar 30, 2026

Mar 28, 2026

Analyst Upgrade: How much upside does Orchestra BioMed Holdings Inc have2026 Chart Watch & Free Verified High Yield Trade Plans - baoquankhu1.vn

Mar 28, 2026

Mar 27, 2026

Orchestra BioMed reports 2025 results, advances pivotal clinical trials - MSN

Mar 27, 2026

Orchestra BioMed (NASDAQ: OBIO) insider reports RSU tax withholding event - Stock Titan

Mar 27, 2026

Orchestra BioMed (OBIO) officer has shares withheld for RSU tax payment - Stock Titan

Mar 27, 2026

Orchestra BioMed (OBIO) insider withholds 32,438 RSU shares for tax - Stock Titan

Mar 27, 2026

Mar 26, 2026

Stock Report: Does Orchestra BioMed Holdings Inc outperform in volatile markets2026 Opening Moves & Technical Analysis for Trade Confirmation - baoquankhu1.vn

Mar 26, 2026

Jefferies cuts Orchestra BioMed stock price target on financing costs By Investing.com - Investing.com Australia

Mar 26, 2026

Jefferies cuts Orchestra BioMed stock price target on financing costs - Investing.com

Mar 26, 2026

Mar 25, 2026

Orchestra BioMed (OBIO) to Release Earnings on Wednesday - MarketBeat

Mar 25, 2026

Mar 22, 2026

Trend Report: How do insiders feel about Orchestra BioMed Holdings IncRate Cut & Precise Swing Trade Alerts - baoquankhu1.vn

Mar 22, 2026

Mar 20, 2026