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Orchestra Biomed Holdings Inc stock is traded at $3.81, with a volume of 13,827. It is up +1.74% in the last 24 hours and down -10.26% over the past month. Orchestra BioMed Holdings Inc is a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships with medical device companies. The company's flagship product candidates are Atrioventricular Interval Modulation Therapy (AVIM Therapy) for the treatment of hypertension, the risk factor for death, and Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the cause of mortality. It has one reportable segment, which consists of the development of clinical and preclinical product candidates through risk-reward sharing partnerships with medical device companies.
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Previous Close:
$3.74
Open:
$3.8
24h Volume:
13,827
Relative Volume:
0.04
Market Cap:
$226.95M
Revenue:
$32.72M
Net Income/Loss:
$-54.64M
P/E Ratio:
-3.3786
EPS:
-1.1277
Net Cash Flow:
$-55.08M
1W Performance:
+2.56%
1M Performance:
-10.26%
6M Performance:
-8.53%
1Y Performance:
+15.65%
1-Day Range:
Value
$3.75
$3.84
1-Week Range:
Value
$3.555
$3.84
52-Week Range:
Value
$2.20
$5.424

Orchestra Biomed Holdings Inc Stock (OBIO) Company Profile

Name
Name
Orchestra Biomed Holdings Inc
Name
Phone
646-343-9298
Name
Address
150 UNION SQUARE DRIVE, NEW HOPE
Name
Employee
86
Name
Twitter
Name
Next Earnings Date
2026-08-11
Name
Latest SEC Filings
Name
OBIO's Discussions on Twitter

Compare OBIO vs VRTX, REGN, ARGX, RVMD, ALNY

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
OBIO icon
OBIO
Orchestra Biomed Holdings Inc
3.79 223.95M 32.72M -54.64M -55.08M -1.1277
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
484.98 121.16B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
673.35 68.78B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
908.04 57.44B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
188.23 40.23B 742.00K -1.37B -1.07B -7.0731
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
282.75 36.28B 4.29B 577.22M 641.34M 4.2086

Orchestra Biomed Holdings Inc Stock (OBIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-10-25 Initiated TD Cowen Buy
Aug-20-25 Downgrade BTIG Research Buy → Neutral
Mar-20-25 Initiated BTIG Research Buy
Jan-02-25 Initiated Barclays Overweight
Aug-22-24 Initiated H.C. Wainwright Buy
Jul-25-24 Initiated B. Riley Securities Buy
Jan-19-24 Initiated Jefferies Buy
Feb-24-23 Initiated Piper Sandler Overweight
Feb-07-23 Initiated Chardan Capital Markets Buy
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Orchestra Biomed Holdings Inc Stock (OBIO) Latest News

pulisher
Jul 26, 2026

Orchestra Biomed Holdings Inc (OBIO) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jul 26, 2026
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Jul 26, 2026

Orchestra Biomed Holdings Inc - TradingKey

Jul 26, 2026
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Jul 25, 2026

Orchestra Biomed Holdings Inc (OBIO) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jul 25, 2026
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Jul 25, 2026

Orchestra BioMed Hldgs Market Sentiment - Benzinga

Jul 25, 2026
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Jul 25, 2026

TradingKey - TradingKey

Jul 25, 2026
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Jul 25, 2026

OBIO|Orchestra Biomed Holdings Inc|Price:3.740|Chg%:+0.100 - TradingKey

Jul 25, 2026
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Jul 25, 2026

Orchestra Biomed Holdings Inc (OBIO) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jul 25, 2026
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Jul 24, 2026

Orchestra Biomed Holdings Inc (OBIO) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jul 24, 2026
pulisher
Jul 22, 2026

Orchestra BioMed: Nearing The First Of Two Pivotal Readouts (NASDAQ:OBIO) - Seeking Alpha

Jul 22, 2026
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Jul 11, 2026

Price to earnings forward of Orchestra BioMed Holdings, Inc. – BOATS:OBIO - TradingView

Jul 11, 2026
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Jul 05, 2026

OBIOOrchestra BioMed Holdings Inc Latest SEC Filings - Finviz

Jul 05, 2026
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Jul 03, 2026

Orchestra BioMed Holdings Inc. (NASDAQ: OBIO) Share Price, OBIO Stock News, OBIO Share Price & Updates - Kalkine

Jul 03, 2026
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Jul 02, 2026

Insider Sell: Darren Sherman Sells 15,000 Shares of Orchestra Bi - GuruFocus

Jul 02, 2026
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Jul 02, 2026

Orchestra BioMed (OBIO) insider sells 15,000 shares under 10b5-1 plan - Stock Titan

Jul 02, 2026
pulisher
Jul 01, 2026

Form 144 Orchestra BioMed Holdings For: 1 July By Investing.com - Investing.com South Africa

Jul 01, 2026
pulisher
Jul 01, 2026

Darren Sherman to sell 15,000 OBIO shares (NASDAQ: OBIO) - Stock Titan

Jul 01, 2026
pulisher
Jun 30, 2026

Orchestra BioMed Joins Russell 3000 and Russell 2000 Indexes - marketscreener.com

Jun 30, 2026
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Jun 30, 2026

Orchestra BioMed Holdings' Market Cap Up US$40m Following Year Of Insider Stock Buying - simplywall.st

Jun 30, 2026
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Jun 29, 2026

Orchestra Biomed Joins Russell 3000® and Russ - Moomoo

Jun 29, 2026
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Jun 29, 2026

Orchestra BioMed Holdings, Inc.(NasdaqGM: OBIO) added to Russell 2000 Index - marketscreener.com

Jun 29, 2026
pulisher
Jun 29, 2026

Orchestra BioMed Holdings, Inc.(NasdaqGM:OBIO) added to Russell 2500 Growth Benchmark - marketscreener.com

Jun 29, 2026
pulisher
Jun 29, 2026

Orchestra BioMed stock rises after Russell index addition By Investing.com - Investing.com Australia

Jun 29, 2026
pulisher
Jun 29, 2026

Orchestra BioMed stock rises after Russell index addition - Investing.com

Jun 29, 2026
pulisher
Jun 29, 2026

Orchestra BioMed (OBIO) Joins Russell 3000 and Russell 2000 Inde - GuruFocus

Jun 29, 2026
pulisher
Jun 29, 2026

Orchestra BioMed joins Russell 2000 and 3000 indexes - Investing.com

Jun 29, 2026
pulisher
Jun 29, 2026

Orchestra BioMed joins Russell 2000 and 3000 indexes By Investing.com - Investing.com Australia

Jun 29, 2026
pulisher
Jun 29, 2026

Orchestra BioMed Holdings, Inc.(NasdaqGM:OBIO) added to Russell 2000 Growth Benchmark - marketscreener.com

Jun 29, 2026
pulisher
Jun 28, 2026

Orchestra BioMed Holdings, Inc.(NasdaqGM:OBIO) added to Russell 3000 Growth Benchmark - marketscreener.com

Jun 28, 2026
pulisher
Jun 28, 2026

Orchestra BioMed Holdings, Inc.(NasdaqGM: OBIO) added to Russell 3000E Index - marketscreener.com

Jun 28, 2026
pulisher
Jun 26, 2026

Orchestra BioMed Holdings, Inc. Actuals & Estimates (NASDAQ:OBIO) - TradingView

Jun 26, 2026
pulisher
Jun 25, 2026

Form 4 Orchestra Biomed Holdings Inc For: 25 June By Investing.com - Investing.com Nigeria

Jun 25, 2026
pulisher
Jun 25, 2026

OBIO Forecast — Price Target — Prediction for 2027 - TradingView

Jun 25, 2026
pulisher
Jun 25, 2026

Orchestra BioMed (OBIO) director awarded RSUs, options and tax shares withheld - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (OBIO) director awarded RSUs and options with tax-share withholding - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (OBIO) director logs RSU tax withholding and 42,553-option grant - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (NASDAQ: OBIO) director receives new RSU and stock option grants - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (OBIO) director receives 42,553 stock options at $4.04 strike - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (OBIO) director granted RSUs, shares withheld for taxes - Stock Titan

Jun 25, 2026
pulisher
Jun 24, 2026

Form 8K Orchestra Biomed Holdings Inc For: 23 June By Investing.com - Investing.com India

Jun 24, 2026
pulisher
Jun 23, 2026

Orchestra BioMed shareholders approve director elections and key proposals at annual meeting By Investing.com - Investing.com Australia

Jun 23, 2026
pulisher
Jun 23, 2026

Orchestra BioMed shareholders approve director elections and key proposals at annual meeting - Investing.com South Africa

Jun 23, 2026
pulisher
Jun 23, 2026

Orchestra BioMed Shareholders Approve Directors and Incentive Plan - TipRanks

Jun 23, 2026
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Jun 23, 2026

Orchestra BioMed (NASDAQ: OBIO) investors approve all 2026 meeting items - Stock Titan

Jun 23, 2026

Orchestra Biomed Holdings Inc Stock (OBIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$106.31
price down icon 0.58%
$118.94
price up icon 1.25%
$35.16
price up icon 0.86%
$58.58
price down icon 0.21%
ONC ONC
$327.04
price up icon 0.80%
$277.50
price up icon 1.54%
Cap:     |  Volume (24h):