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Orchestra Biomed Holdings IncOBIO
$5.713.38%-0.20

Orchestra Biomed Holdings Inc (OBIO)

Date: 2026-11-02 16:00O: 6.00H: 6.02L: 5.66C: 5.72Vol: 235.2k
Orchestra Biomed Holdings Inc stock is traded at $5.71, with a volume of 244,943. It is down -3.38% in the last 24 hours and down -4.03% over the past month. Orchestra BioMed Holdings Inc is a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships with medical device companies. The company's flagship product candidates are Atrioventricular Interval Modulation Therapy (AVIM Therapy) for the treatment of hypertension, the risk factor for death, and Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the cause of mortality. It has one reportable segment, which consists of the development of clinical and preclinical product candidates through risk-reward sharing partnerships with medical device companies.
Previous Close:
$5.91
Open:
$6.00
24h Volume:
244,943
Relative Volume:
0.63
Market Cap:
$343.20M
Revenue:
$32.72M
Net Income/Loss:
-$54.64M
P/E Ratio:
-
EPS:
-$1.13
Net Cash Flow:
-$55.08M
1W Performance:
+2.88%
1M Performance:
-4.03%
6M Performance:
+43.83%
1Y Performance:
+46.41%
1-Day Range:
$5.66$6.02
1-Week Range:
$5.52$6.16
52-Week Range:
$3.46$6.50

Orchestra Biomed Holdings Inc Stock (OBIO) Company Profile

Name
Orchestra Biomed Holdings Inc
Phone
646-343-9298
Address
150 UNION SQUARE DRIVE, NEW HOPE, USA
Employee
86
X
-
Next Earnings Date
2026-11-09
Latest SEC Filings
SEC
OBIO's Discussions on X
X

Compare OBIO vs VRTX, REGN, MRNA, ARGX, ONC

StocksMarket CapRevenueNet IncomeCash FlowEPS
OBIO
Orchestra Biomed Holdings Inc
$343.20M$31.98M-$59.03M-$55.08M-$1.13
VRTX
Vertex Pharmaceuticals Inc
$138.47B$12.59B$4.41B$3.71B$16.87
REGN
Regeneron Pharmaceuticals Inc
$99.83B$16.90B$4.82B$3.79B$41.04
MRNA
Moderna Inc
$87.64B$2.23B-$3.15B-$1.60B-$8.15
ARGX
Argen X Se Adr
$55.13B$4.16B$1.29B$734.26M$19.58
ONC
Beone Medicines Ltd Adr
$41.12B$6.13B$655.71M$1.10B$4.48

Orchestra Biomed Holdings Inc Stock (OBIO) Upgrades & Downgrades

DateActionAnalystRating Change
Sep-10-26UpgradeBTIG ResearchNeutral → Buy
Dec-10-25InitiatedTD CowenBuy
Aug-20-25DowngradeBTIG ResearchBuy → Neutral
Mar-20-25InitiatedBTIG ResearchBuy

Orchestra Biomed Holdings Inc Stock (OBIO) Financials Data

PeriodTrendFY 2025FY 2024FY 2023FY 2022
Period End Date2025-12-312024-12-312023-12-312022-12-31
Revenue USD (M)33.482.642.76-
Cost of revenue USD (M)0.190.200.19-
Gross profit USD (M)--2.57-
Research and development USD (M)58.1942.8033.82-
Operating expenses USD (M)85.2966.9454.08-
Operating income USD (M)-51.81-64.30-51.51-3.08
Income before tax USD (M)---49.12-
Income tax expense USD (M)0.00---
Net income USD (M)-52.70-61.02-49.12-2.74
Basic EPS USD/shares-1.11-1.66-1.48-0.17
Diluted EPS USD/shares-1.11-1.66-1.48-0.17
Basic weighted shares shares (M)47.7536.8233.2316.43
Diluted weighted shares shares (M)47.7536.8233.2316.43
Selling, general and administrative USD (M)26.9123.9320.26-

Orchestra Biomed Holdings Inc Stock (OBIO) Insider Trading

  • Sherman DarrenOct 01 '26
    Officer
    Transaction
    Proposed Sale
    Cost
    $6.27
    #Shares
    15,000
    Value ($)
    94,050
    #Shares Total
    0
  • Hochman David PSep 03 '26
    See Remarks
    Transaction
    Buy
    Cost
    $4.79
    #Shares
    10,000
    Value ($)
    47,900
    #Shares Total
    1,070,746
  • Sherman DarrenSep 01 '26
    Officer
    Transaction
    Proposed Sale
    Cost
    $5.02
    #Shares
    15,000
    Value ($)
    75,300
    #Shares Total
    0
  • Sherman DarrenSep 01 '26
    See Remarks
    Transaction
    Sale
    Cost
    $4.94
    #Shares
    15,000
    Value ($)
    74,100
    #Shares Total
    1,134,402
  • Sherman DarrenAug 26 '26
    See Remarks
    Transaction
    Buy
    Cost
    $5.33
    #Shares
    2,000
    Value ($)
    10,660
    #Shares Total
    2,000
  • Sherman DarrenAug 03 '26
    Officer
    Transaction
    Proposed Sale
    Cost
    $4.09
    #Shares
    15,000
    Value ($)
    61,292
    #Shares Total
    0
  • Sherman DarrenAug 03 '26
    See Remarks
    Transaction
    Sale
    Cost
    $4.09
    #Shares
    15,000
    Value ($)
    61,350
    #Shares Total
    1,154,327
  • Sherman DarrenJul 01 '26
    Officer
    Transaction
    Proposed Sale
    Cost
    $4.32
    #Shares
    15,000
    Value ($)
    64,800
    #Shares Total
    0
  • Sherman DarrenJun 01 '26
    Officer
    Transaction
    Proposed Sale
    Cost
    $3.87
    #Shares
    15,000
    Value ($)
    58,050
    #Shares Total
    0
  • Sherman DarrenJun 01 '26
    See Remarks
    Transaction
    Sale
    Cost
    $3.87
    #Shares
    15,000
    Value ($)
    58,050
    #Shares Total
    1,184,327
Insider TradingRelationshipDateTransactionCost#SharesValue ($)#Shares Total
Sherman DarrenOfficerOct 01 '26Proposed Sale$6.2715,00094,0500
Hochman David PSee RemarksSep 03 '26Buy$4.7910,00047,9001,070,746
Sherman DarrenOfficerSep 01 '26Proposed Sale$5.0215,00075,3000
Sherman DarrenSee RemarksSep 01 '26Sale$4.9415,00074,1001,134,402
Sherman DarrenSee RemarksAug 26 '26Buy$5.332,00010,6602,000
Sherman DarrenOfficerAug 03 '26Proposed Sale$4.0915,00061,2920
Sherman DarrenSee RemarksAug 03 '26Sale$4.0915,00061,3501,154,327
Sherman DarrenOfficerJul 01 '26Proposed Sale$4.3215,00064,8000
Sherman DarrenOfficerJun 01 '26Proposed Sale$3.8715,00058,0500
Sherman DarrenSee RemarksJun 01 '26Sale$3.8715,00058,0501,184,327

Orchestra Biomed Holdings Inc Stock (OBIO) Latest News

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