5.08
price up icon7.17%   0.34
after-market After Hours: 5.08
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Orchestra Biomed Holdings Inc stock is traded at $5.08, with a volume of 478.14K. It is up +7.17% in the last 24 hours and up +18.97% over the past month. Orchestra BioMed Holdings Inc is a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships with medical device companies. The company's flagship product candidates are Atrioventricular Interval Modulation Therapy (AVIM Therapy) for the treatment of hypertension, the risk factor for death, and Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the cause of mortality. It has one reportable segment, which consists of the development of clinical and preclinical product candidates through risk-reward sharing partnerships with medical device companies.
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Previous Close:
$4.74
Open:
$4.71
24h Volume:
478.14K
Relative Volume:
1.39
Market Cap:
$305.33M
Revenue:
$32.72M
Net Income/Loss:
$-54.64M
P/E Ratio:
-4.5047
EPS:
-1.1277
Net Cash Flow:
$-55.08M
1W Performance:
-2.03%
1M Performance:
+18.97%
6M Performance:
+11.40%
1Y Performance:
+85.40%
1-Day Range:
Value
$4.71
$5.14
1-Week Range:
Value
$4.71
$5.3492
52-Week Range:
Value
$2.20
$5.78

Orchestra Biomed Holdings Inc Stock (OBIO) Company Profile

Name
Name
Orchestra Biomed Holdings Inc
Name
Phone
646-343-9298
Name
Address
150 UNION SQUARE DRIVE, NEW HOPE
Name
Employee
86
Name
Twitter
Name
Next Earnings Date
2026-08-11
Name
Latest SEC Filings
Name
OBIO's Discussions on Twitter

Compare OBIO vs VRTX, REGN, ARGX, MRNA, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
OBIO icon
OBIO
Orchestra Biomed Holdings Inc
5.08 326.37M 32.72M -54.64M -55.08M -1.1277
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
546.12 136.93B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
827.72 85.11B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
1,033.15 64.95B 4.16B 1.29B 734.26M 19.58
MRNA icon
MRNA
Moderna Inc
145.55 53.23B 2.23B -3.19B -1.60B -8.1462
RVMD icon
RVMD
Revolution Medicines Inc
210.02 45.38B 742.00K -1.37B -1.07B -7.0731

Orchestra Biomed Holdings Inc Stock (OBIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-10-25 Initiated TD Cowen Buy
Aug-20-25 Downgrade BTIG Research Buy → Neutral
Mar-20-25 Initiated BTIG Research Buy
Jan-02-25 Initiated Barclays Overweight
Aug-22-24 Initiated H.C. Wainwright Buy
Jul-25-24 Initiated B. Riley Securities Buy
Jan-19-24 Initiated Jefferies Buy
Feb-24-23 Initiated Piper Sandler Overweight
Feb-07-23 Initiated Chardan Capital Markets Buy
View All

Orchestra Biomed Holdings Inc Stock (OBIO) Latest News

pulisher
Sep 02, 2026

Orchestra BioMed (OBIO) president sells 15,000 shares under trading plan - Stock Titan

Sep 02, 2026
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Sep 02, 2026

Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - Yahoo Finance

Sep 02, 2026
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Sep 01, 2026

Insider plans to sell 15,000 Orchestra BioMed (OBIO) shares - Stock Titan

Sep 01, 2026
pulisher
Aug 28, 2026

Orchestra BioMed (OBIO) CFO logs 3,076-share tax withholding - Stock Titan

Aug 28, 2026
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Aug 28, 2026

Orchestra BioMed (NASDAQ: OBIO) exec cites tax share withholding and son's 2,000-share buy - Stock Titan

Aug 28, 2026
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Aug 28, 2026

Orchestra BioMed (OBIO) officer sees shares withheld for RSU taxes - Stock Titan

Aug 28, 2026
pulisher
Aug 27, 2026

Avoiding Lag: Real-Time Signals in (OBIO) Movement - Stock Traders Daily

Aug 27, 2026
pulisher
Aug 20, 2026

Orchestra BioMed to Participate in the Wells Fargo 21st Annual Healthcare Conference - GlobeNewswire

Aug 20, 2026
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Aug 20, 2026

Orchestra BioMed CEO to meet investors across two days in September - Stock Titan

Aug 20, 2026
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Aug 19, 2026

Insiders Buying Orchestra BioMed Holdings Might Wish They Invested More, Stock Gains 29% - Moomoo

Aug 19, 2026
pulisher
Aug 19, 2026

Orchestra (OBIO) Q2 2026 Results: Profit Per Share Clears Its Benchmark for the Current Session; Investor Response: Shares Finish 19.92% Higher in Latest TradingInvestor Earnings Call - vinanet.vn

Aug 19, 2026
pulisher
Aug 18, 2026

Orchestra (OBIO) Reported Results Review: EPS Prints Above Forecast for the Current Session; Price Action: Shares Close 19.92% Higher at the CloseProfit Recovery Report - vinanet.vn

Aug 18, 2026
pulisher
Aug 18, 2026

Orchestra BioMed Loss Widens as Pivotal Trials Advance - MyChesCo

Aug 18, 2026
pulisher
Aug 16, 2026

Orchestra BioMed Holdings, Inc. (NASDAQ:OBIO) Receives Consensus Rating of "Moderate Buy" from Brokerages - MarketBeat

Aug 16, 2026
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Aug 14, 2026

Orchestra BioMed (OBIO) director withholds 3,761 shares to cover RSU tax bill - Stock Titan

Aug 14, 2026
pulisher
Aug 14, 2026

Orchestra BioMed (OBIO) director uses 5,145 shares to cover RSU tax withholding - Stock Titan

Aug 14, 2026
pulisher
Aug 14, 2026

Orchestra BioMed (OBIO) director has 4,885 shares withheld for RSU tax - Stock Titan

Aug 14, 2026
pulisher
Aug 14, 2026

Orchestra BioMed (OBIO) director reports 4,238 RSU tax-withholding shares - Stock Titan

Aug 14, 2026
pulisher
Aug 14, 2026

Orchestra BioMed (OBIO) Holds Gains at $4.45, Consolidating Between Key Technical LevelsComposite Profile - vinanet.vn

Aug 14, 2026
pulisher
Aug 14, 2026

Research Analysts Offer Predictions for OBIO Q3 Earnings - MarketBeat

Aug 14, 2026
pulisher
Aug 13, 2026

Wall Street Analysts Are Bullish on Top Healthcare Picks - theglobeandmail.com

Aug 13, 2026
pulisher
Aug 13, 2026

Orchestra BioMed Holdings, Inc. (NASDAQ:OBIO) Consensus Forecasts Have Become A Little Darker Since Its Latest Report - simplywall.st

Aug 13, 2026
pulisher
Aug 11, 2026

Piper Sandler Maintains Orchestra BioMed(OBIO.US) With Buy Rating, Raises Target Price to $10 - Moomoo

Aug 11, 2026
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Aug 11, 2026

Orchestra BioMed Holdings, Inc. Stock 12‑Month Price Target Raised to $12.33, Implies 177% Upside - TradingView

Aug 11, 2026
pulisher
Aug 11, 2026

Orchestra Biomed Holdings earnings beat by $0.01, revenue fell short of estimates - Investing.com Canada

Aug 11, 2026
pulisher
Aug 10, 2026

Orchestra Biomed Holdings Inc reports results for the quarter ended June 30Earnings Summary - TradingView

Aug 10, 2026
pulisher
Aug 10, 2026

Orchestra BioMed Reports Second Quarter 2026 Financial Results and Highlights Recent Business Updates - Investing News Network

Aug 10, 2026
pulisher
Aug 10, 2026

OBIO Looks 87.4% Undervalued on GF Value™ Despite Challenging Fu - GuruFocus

Aug 10, 2026
pulisher
Aug 10, 2026

Orchestra BioMed reports $24.1M Q2 loss, secures $35M capital - scanx.trade

Aug 10, 2026
pulisher
Aug 10, 2026

Orchestra BioMed Holdings, Inc. (OBIO) Reports Q2 Loss, Misses Revenue Estimates - Yahoo Finance

Aug 10, 2026
pulisher
Aug 10, 2026

Orchestra BioMed (NASDAQ:OBIO) Announces Quarterly Earnings Results, Misses Estimates By $0.03 EPS - MarketBeat

Aug 10, 2026
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Aug 10, 2026

Orchestra BioMed Reports Q2 2026 Results and Updates Progress on BACKBEAT and Virtue Pivotal Trials - Moomoo

Aug 10, 2026
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Aug 10, 2026

Orchestra BioMed (NASDAQ: OBIO) widens H1 2026 loss amid heavy R&D spend - Stock Titan

Aug 10, 2026
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Aug 07, 2026

Orchestra Biomed Holdings Inc (OBIO) Stock News Today - TradingKey

Aug 07, 2026
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Aug 07, 2026

Orchestra Biomed Holdings Inc (OBIO) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Aug 07, 2026
pulisher
Aug 04, 2026

Orchestra BioMed (OBIO) Insider Darren Sherman Sells 15,000 Shar - GuruFocus

Aug 04, 2026
pulisher
Aug 04, 2026

Darren Sherman Sells 15,000 Shares of Orchestra BioMed (NASDAQ:OBIO) Stock - marketbeat.com

Aug 04, 2026
pulisher
Aug 04, 2026

Orchestra BioMed (OBIO) insider sale under 10b5-1 plan on August 3, 2026 - Stock Titan

Aug 04, 2026
pulisher
Aug 04, 2026

Orchestra BioMed (OBIO) Projected to Announce Quarterly Earnings on Tuesday - marketbeat.com

Aug 04, 2026
pulisher
Aug 03, 2026

Orchestra BioMed (NASDAQ: OBIO) insider details Rule 144 sales of 45,000 shares - Stock Titan

Aug 03, 2026
pulisher
Aug 01, 2026

Orchestra BioMed (OBIO) Holds Near $4.00 as Shares Test Support ZoneAnalyst Upgrade Stocks - vinanet.vn

Aug 01, 2026
pulisher
Jul 31, 2026

Orchestra Biomed Holdings Inc expected to post a loss of 39 cents a shareEarnings Preview - TradingView

Jul 31, 2026
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Jul 28, 2026

OBIO|Orchestra Biomed Holdings Inc|Price:3.825|Chg%:+0.085 - TradingKey

Jul 28, 2026
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Jul 27, 2026

Orchestra Biomed Holdings Inc (OBIO) Income Statement - TradingKey

Jul 27, 2026
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Jul 27, 2026

Orchestra Biomed Holdings Inc (OBIO) Balance Sheet - TradingKey

Jul 27, 2026
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Jul 27, 2026

Orchestra Biomed Holdings Inc (OBIO) Institutional Confidence - TradingKey

Jul 27, 2026
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Jul 27, 2026

Orchestra Biomed Holdings Inc (OBIO) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

Jul 27, 2026
pulisher
Jul 27, 2026

Orchestra BioMed Holdings, Inc. Revenue Breakdown – NASDAQ:OBIO - TradingView

Jul 27, 2026
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Jul 26, 2026

Orchestra Biomed Holdings Inc (OBIO) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jul 26, 2026
pulisher
Jul 26, 2026

OBIO|Orchestra Biomed Holdings Inc|Price:3.980|Chg%:-0.010 - TradingKey

Jul 26, 2026
pulisher
Jul 26, 2026

OBIO Q1 2026 Earnings: Narrower-Than-Expected Loss as Pre-Revenue Biotech Advances PipelineHealthcare Earnings Report - po-news-eg.net

Jul 26, 2026

Orchestra Biomed Holdings Inc Stock (OBIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Orchestra Biomed Holdings Inc Stock (OBIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Sherman Darren
See Remarks
Aug 03 '26
Sale
4.09
15,000
61,350
1,154,327
$103.76
price up icon 0.86%
$126.29
price down icon 0.31%
$63.96
price up icon 0.13%
$266.11
price up icon 0.61%
ONC ONC
$358.26
price down icon 1.22%
$210.02
price down icon 0.40%
Cap:     |  Volume (24h):