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Orchestra Biomed Holdings Inc stock is traded at $4.1522, with a volume of 160.77K. It is down -0.72% in the last 24 hours and up +6.67% over the past month. Orchestra BioMed Holdings Inc is a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships with medical device companies. The company's flagship product candidates are Atrioventricular Interval Modulation Therapy (AVIM Therapy) for the treatment of hypertension, the risk factor for death, and Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the cause of mortality. It has one reportable segment, which consists of the development of clinical and preclinical product candidates through risk-reward sharing partnerships with medical device companies.
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Previous Close:
$4.19
Open:
$4.16
24h Volume:
160.77K
Relative Volume:
0.53
Market Cap:
$249.10M
Revenue:
$32.72M
Net Income/Loss:
$-54.64M
P/E Ratio:
-3.682
EPS:
-1.1277
Net Cash Flow:
$-55.08M
1W Performance:
-12.42%
1M Performance:
+6.67%
6M Performance:
-6.52%
1Y Performance:
+43.94%
1-Day Range:
Value
$4.06
$4.25
1-Week Range:
Value
$4.06
$4.79
52-Week Range:
Value
$2.20
$5.424

Orchestra Biomed Holdings Inc Stock (OBIO) Company Profile

Name
Name
Orchestra Biomed Holdings Inc
Name
Phone
646-343-9298
Name
Address
150 UNION SQUARE DRIVE, NEW HOPE
Name
Employee
86
Name
Twitter
Name
Next Earnings Date
2026-08-11
Name
Latest SEC Filings
Name
OBIO's Discussions on Twitter

Compare OBIO vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
OBIO icon
OBIO
Orchestra Biomed Holdings Inc
4.16 258.39M 32.72M -54.64M -55.08M -1.1277
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
528.31 126.07B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
648.10 65.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
926.91 57.70B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
313.73 40.19B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
189.17 39.82B 742.00K -1.37B -1.07B -7.0731

Orchestra Biomed Holdings Inc Stock (OBIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Dec-10-25 Initiated TD Cowen Buy
Aug-20-25 Downgrade BTIG Research Buy → Neutral
Mar-20-25 Initiated BTIG Research Buy
Jan-02-25 Initiated Barclays Overweight
Aug-22-24 Initiated H.C. Wainwright Buy
Jul-25-24 Initiated B. Riley Securities Buy
Jan-19-24 Initiated Jefferies Buy
Feb-24-23 Initiated Piper Sandler Overweight
Feb-07-23 Initiated Chardan Capital Markets Buy
View All

Orchestra Biomed Holdings Inc Stock (OBIO) Latest News

pulisher
Jul 01, 2026

Form 144 Orchestra BioMed Holdings For: 1 July By Investing.com - Investing.com South Africa

Jul 01, 2026
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Jul 01, 2026

Darren Sherman to sell 15,000 OBIO shares (NASDAQ: OBIO) - Stock Titan

Jul 01, 2026
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Jun 30, 2026

Orchestra BioMed Joins Russell 3000 and Russell 2000 Indexes - marketscreener.com

Jun 30, 2026
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Jun 30, 2026

Orchestra BioMed Holdings' Market Cap Up US$40m Following Year Of Insider Stock Buying - simplywall.st

Jun 30, 2026
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Jun 29, 2026

Orchestra BioMed Holdings, Inc.(NasdaqGM: OBIO) added to Russell 2000 Index - marketscreener.com

Jun 29, 2026
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Jun 29, 2026

Orchestra BioMed stock rises after Russell index addition - Investing.com

Jun 29, 2026
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Jun 29, 2026

Orchestra BioMed (OBIO) Joins Russell 3000 and Russell 2000 Inde - GuruFocus

Jun 29, 2026
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Jun 29, 2026

Orchestra BioMed joins Russell 2000 and 3000 indexes - Investing.com

Jun 29, 2026
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Jun 29, 2026

Orchestra BioMed lands in Russell indexes tracking $12.2T - Stock Titan

Jun 29, 2026
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Jun 29, 2026

Orchestra BioMed Holdings, Inc.(NasdaqGM:OBIO) added to Russell 2000 Growth Benchmark - marketscreener.com

Jun 29, 2026
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Jun 26, 2026

Orchestra BioMed Holdings, Inc. Actuals & Estimates (NASDAQ:OBIO) - TradingView

Jun 26, 2026
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Jun 25, 2026

Form 4 Orchestra Biomed Holdings Inc For: 25 June By Investing.com - Investing.com Nigeria

Jun 25, 2026
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Jun 25, 2026

OBIO Forecast — Price Target — Prediction for 2027 - TradingView

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (OBIO) director awarded RSUs, options and tax shares withheld - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (OBIO) director awarded RSUs and options with tax-share withholding - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (OBIO) director logs RSU tax withholding and 42,553-option grant - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (NASDAQ: OBIO) director receives new RSU and stock option grants - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (OBIO) director receives 42,553 stock options at $4.04 strike - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Orchestra BioMed (OBIO) director granted RSUs, shares withheld for taxes - Stock Titan

Jun 25, 2026
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Jun 24, 2026

Orchestra Biomed Holdings Inc (OBIO) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jun 24, 2026
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Jun 23, 2026

Orchestra BioMed shareholders approve director elections and key proposals at annual meeting By Investing.com - Investing.com Australia

Jun 23, 2026
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Jun 23, 2026

Orchestra BioMed shareholders approve director elections and key proposals at annual meeting - Investing.com South Africa

Jun 23, 2026
pulisher
Jun 23, 2026

Form 8K Orchestra Biomed Holdings Inc For: 23 June By Investing.com - Investing.com Nigeria

Jun 23, 2026
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Jun 23, 2026

Orchestra BioMed Shareholders Approve Directors and Incentive Plan - TipRanks

Jun 23, 2026
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Jun 23, 2026

Orchestra BioMed (NASDAQ: OBIO) investors approve all 2026 meeting items - Stock Titan

Jun 23, 2026
pulisher
Jun 22, 2026

Orchestra BioMed Holdings (OBIO) Bounces from Support: +2.26% Gain Signals Potential RecoveryWedge Breakout - dars.gov.et

Jun 22, 2026
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Jun 18, 2026

Orchestra BioMed Holdings (OBIO) Gets a Hold from BTIG - The Globe and Mail

Jun 18, 2026
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Jun 18, 2026

Orchestra Biomed Holdings Inc (OBIO) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jun 18, 2026
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Jun 18, 2026

Orchestra Biomed Holdings Inc (OBIO) Institutional Confidence - TradingKey

Jun 18, 2026
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Jun 17, 2026

Orchestra Biomed Holdings Inc (OBIO) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Orchestra Biomed Holdings Inc (OBIO) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jun 17, 2026
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Jun 17, 2026

Orchestra Biomed Holdings Inc (OBIO) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Orchestra Biomed Holdings Inc (OBIO) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

Jun 17, 2026
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Jun 17, 2026

Orchestra Biomed Holdings Inc (OBIO) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jun 17, 2026
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Jun 17, 2026

Orchestra Biomed Holdings Inc - TradingKey

Jun 17, 2026
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Jun 13, 2026

OBIO Q1 2026 Earnings: Narrower-than-Expected Loss as Clinical Pipeline AdvancesRevenue Recognition Risk - newsline.com

Jun 13, 2026
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Jun 12, 2026

Orchestra BioMed (OBIO) Edges Higher, Testing Key Resistance Zone on Modest VolumeLow Beta Factor - newsline.com

Jun 12, 2026
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Jun 12, 2026

Orchestra BioMed (NASDAQ: OBIO) CFO has shares withheld to cover RSU tax obligations - Stock Titan

Jun 12, 2026
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Jun 12, 2026

Orchestra BioMed (OBIO) insider uses 6,566 shares to cover RSU taxes - Stock Titan

Jun 12, 2026
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Jun 09, 2026

Orchestra BioMed Grants Equity Awards to New Employees - MyChesCo

Jun 09, 2026
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Jun 08, 2026

Number of shareholders of Orchestra BioMed Holdings, Inc. – NASDAQ:OBIO - TradingView

Jun 08, 2026
pulisher
Jun 05, 2026

Orchestra BioMed Holdings (OBIO) Slips 2.26% as Shares Test Support Near $3.70Chart Pattern Alerts - newsline.com

Jun 05, 2026
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Jun 05, 2026

Orchestra BioMed receives $20 million from Medtronic - Investing.com

Jun 05, 2026
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Jun 04, 2026

OBIO: Upcoming BackBeat and Virtue trial milestones signal strong growth and partnership-driven value - TradingView

Jun 04, 2026
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Jun 03, 2026

12 Health Care Stocks Moving In Wednesday's After-Market Session - Benzinga

Jun 03, 2026
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Jun 03, 2026

Insider Sell Alert: Darren Sherman Sells Shares of Orchestra Bio - GuruFocus

Jun 03, 2026
pulisher
Jun 02, 2026

Insider Sell Alert: Darren Sherman Sells Shares of Orchestra BioMed Holdings Inc (OBIO) - GuruFocus

Jun 02, 2026
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Jun 02, 2026

Orchestra BioMed (OBIO) director adds 5,000 shares in open-market buy - Stock Titan

Jun 02, 2026
pulisher
Jun 02, 2026

Orchestra BioMed (OBIO) director Darren Sherman sells 15,000 shares under 10b5-1 plan - Stock Titan

Jun 02, 2026
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Jun 02, 2026

Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - Caledonian Record

Jun 02, 2026
pulisher
Jun 02, 2026

Orchestra BioMed (OBIO) Rebounds: Key Levels to Watch After 2% GainPCR Moving Average - dars.gov.et

Jun 02, 2026

Orchestra Biomed Holdings Inc Stock (OBIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Orchestra Biomed Holdings Inc Stock (OBIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Hochman David P
See Remarks
Jun 01 '26
Buy
3.83
5,000
19,150
1,064,029
Sherman Darren
See Remarks
Jun 01 '26
Sale
3.87
15,000
58,050
1,184,327
$112.33
price up icon 0.72%
$35.01
price up icon 0.17%
$57.48
price down icon 0.50%
ONC ONC
$310.87
price up icon 4.52%
$83.25
price up icon 4.33%
$191.12
price up icon 0.74%
Cap:     |  Volume (24h):