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Monopar Therapeutics Inc stock is traded at $110.14, with a volume of 122.24K. It is down -3.04% in the last 24 hours and up +1.27% over the past month. Monopar Therapeutics Inc is a clinical-stage biopharmaceutical company developing a treatment for Wilson disease and novel radiopharmaceuticals for oncology. Its Wilson disease product candidate is ALXN1840, a late-stage, investigational once-daily, oral medicine. The group radiopharmaceutical programs consist of Phase 1-stage MNPR-101-Zr for imaging cancers, and Phase 1a-stage MNPR-101-Lu and late preclinical-stage MNPR-101-Ac for the treatment of cancers that express urokinase plasminogen activator receptor (uPAR). It build drug development pipeline through both in-house efforts and licensing of late preclinical- and clinical-stage therapeutics. The Company operates as a single reportable segment, focusing on the development of clinical and preclinical product candidates.
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Previous Close:
$113.94
Open:
$112.85
24h Volume:
122.24K
Relative Volume:
0.56
Market Cap:
$738.44M
Revenue:
-
Net Income/Loss:
$-14.99M
P/E Ratio:
-53.30
EPS:
-2.0665
Net Cash Flow:
$-10.01M
1W Performance:
+2.56%
1M Performance:
+1.27%
6M Performance:
+101.59%
1Y Performance:
+206.38%
1-Day Range:
Value
$109.14
$112.86
1-Week Range:
Value
$104.48
$117.50
52-Week Range:
Value
$32.77
$124.82

Monopar Therapeutics Inc Stock (MNPR) Company Profile

Name
Name
Monopar Therapeutics Inc
Name
Phone
(847) 388-0349
Name
Address
1000 SKOKIE BLVD SUITE 350, WILMETTE
Name
Employee
22
Name
Twitter
Name
Next Earnings Date
2026-08-11
Name
Latest SEC Filings
Name
MNPR's Discussions on Twitter

Compare MNPR vs VRTX, REGN, ARGX, MRNA, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
MNPR icon
MNPR
Monopar Therapeutics Inc
110.02 744.25M 0 -14.99M -10.01M -2.0665
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
541.86 136.93B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
790.45 85.11B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
1,030.44 64.95B 4.16B 1.29B 734.26M 19.58
MRNA icon
MRNA
Moderna Inc
136.57 53.23B 2.23B -3.19B -1.60B -8.1462
RVMD icon
RVMD
Revolution Medicines Inc
206.79 45.38B 742.00K -1.37B -1.07B -7.0731

Monopar Therapeutics Inc Stock (MNPR) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-09-26 Initiated Morgan Stanley Overweight
Nov-14-25 Downgrade Raymond James Strong Buy → Outperform
Nov-10-25 Initiated Leerink Partners Outperform
Oct-13-25 Initiated Barclays Overweight
Sep-09-25 Initiated BTIG Research Buy
Sep-03-25 Initiated Oppenheimer Outperform
Sep-03-25 Initiated Raymond James Strong Buy
Aug-26-25 Resumed H.C. Wainwright Buy
Jul-07-25 Initiated Cantor Fitzgerald Overweight
Jun-23-25 Initiated Chardan Capital Markets Buy
Mar-19-25 Resumed Piper Sandler Overweight
Jan-10-25 Initiated Piper Sandler Overweight
Oct-11-24 Initiated Rodman & Renshaw Buy
Jan-28-21 Initiated ROTH Capital Buy
View All

Monopar Therapeutics Inc Stock (MNPR) Latest News

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Aug 20, 2026

MNPR drops as short-term selling pressure persists - Traders Union

Aug 20, 2026
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Aug 20, 2026

Morgan Stanley Maintains Monopar Therapeutics(MNPR.US) With Buy Rating, Raises Target Price to $130 - Moomoo

Aug 20, 2026
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Aug 20, 2026

What's behind Monopar Therapeutics's latest stock pullback? - Traders Union

Aug 20, 2026
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Aug 20, 2026

Monopar (MNPR) Chart: Retreats 2.41% to $120.85 in the Latest Reading; Price Levels: $114.81 and $126.89 Define the Nearby Reference Levels under the Current SnapshotLeveraged ETF Flow - vinanet.vn

Aug 20, 2026
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Aug 19, 2026

Monopar appoints medical affairs head, presents at liver meeting By Investing.com - Investing.com South Africa

Aug 19, 2026
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Aug 19, 2026

Monopar appoints medical affairs head, presents at liver meeting - Investing.com

Aug 19, 2026
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Aug 19, 2026

Monopar Appoints Jeffrey D. Kent, M.D., as Executive Vice President, Head of Medical Affairs; Announces Two ALXN1840 Presentations at AASLDThe Liver Meeting® 2026 - The Manila Times

Aug 19, 2026
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Aug 18, 2026

Monopar (MNPR) Price Update: Rises 1.94% to $118.75 at the Close; Price Context: the $112.81 to $124.69 Range Remains in Focus in the Latest ReadingLate Stage Breakouts - vinanet.vn

Aug 18, 2026
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Aug 18, 2026

Monopar: Licensing Agreement, Rolling NDA Submission Serve As Catalysts For ‘Strong Buy’ - Seeking Alpha

Aug 18, 2026
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Aug 16, 2026

(MNPR) as a Liquidity Pulse for Institutional Tactics - Stock Traders Daily

Aug 16, 2026
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Aug 16, 2026

Monopar Therapeutics (NASDAQ:MNPR) Cut to Sell at Wall Street Zen - MarketBeat

Aug 16, 2026
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Aug 15, 2026

Zacks Research Downgrades Monopar Therapeutics (NASDAQ:MNPR) to Hold - MarketBeat

Aug 15, 2026
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Aug 14, 2026

Equities Analysts Offer Predictions for MNPR FY2029 Earnings - MarketBeat

Aug 14, 2026
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Aug 14, 2026

Buy Rating Reiterated on Monopar as ALXN-1840 Advances in Wilson Disease; $125 Price Target Maintained - TipRanks

Aug 14, 2026
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Aug 13, 2026

Monopar Therapeutics Shares Drop After Downgrade From Cantor Fitzgerald - marketscreener.com

Aug 13, 2026
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Aug 13, 2026

Monopar downgraded to Neutral at Cantor (MNPR:NASDAQ) - Seeking Alpha

Aug 13, 2026
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Aug 13, 2026

This Stubhub Analyst Turns Bearish; Here Are Top 5 Downgrades For Thursday - Benzinga

Aug 13, 2026
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Aug 13, 2026

MNPR Maintained by Barclays -- Price Target Raised to $128.00 - GuruFocus

Aug 13, 2026
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Aug 13, 2026

MNPR Downgraded by Cantor Fitzgerald -- Price Target Raised to $119 - GuruFocus

Aug 13, 2026
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Aug 13, 2026

Monopar Therapeutics Releases Q2 2026 Financial Results - AlphaStreet

Aug 13, 2026
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Aug 13, 2026

Cantor downgrades Monopar stock on valuation after 90% rally - Investing.com

Aug 13, 2026
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Aug 13, 2026

Cantor downgrades Monopar stock on valuation after 90% rally By Investing.com - Investing.com Canada

Aug 13, 2026
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Aug 13, 2026

MONOPAR THERAPEUTICS INC. : BTIG RAISES TARGET PRICE TO $133 FROM $117 - Bitget

Aug 13, 2026
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Aug 12, 2026

Boris Peaker Maintains Buy Rating on Monopar, Reaffirming Unchanged $130 Price Target on ALXN1840’s Strong Clinical and Regulatory Profile - TipRanks

Aug 12, 2026
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Aug 12, 2026

Saturn V Capital shows sub-5% Monopar Therapeutics (MNPR) stake in 13G/A - Stock Titan

Aug 12, 2026
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Aug 12, 2026

Monopar Therapeutics stock price target raised to $133 by BTIG - Investing.com Canada

Aug 12, 2026
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Aug 12, 2026

MNPR Maintained by BTIG -- Price Target Raised to $133 - GuruFocus

Aug 12, 2026
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Aug 12, 2026

BTIG Research Forecasts Strong Price Appreciation for Monopar Therapeutics (NASDAQ:MNPR) Stock - MarketBeat

Aug 12, 2026
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Aug 12, 2026

Monopar Therapeutics (NASDAQ:MNPR) Issues Quarterly Earnings Results, Misses Expectations By $0.13 EPS - MarketBeat

Aug 12, 2026
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Aug 12, 2026

Adage Capital discloses 4.76% Monopar Therapeutics (MNPR) stake including warrants - Stock Titan

Aug 12, 2026
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Aug 12, 2026

Form 8K Monopar Therapeutics Inc For: 12 August By Investing.com - Investing.com Nigeria

Aug 12, 2026
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Aug 12, 2026

Monopar Therapeutics' Q2 Net Loss Widens - marketscreener.com

Aug 12, 2026
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Aug 12, 2026

Monopar Therapeutics Reports Second Quarter 2026 Financial Results and Provides Business Updates - The Manila Times

Aug 12, 2026
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Aug 12, 2026

Monopar Therapeutics Reports Second Quarter 2026 Financial Results and Provides Business Update on ALXN1840 NDA Submission - Quiver Quantitative

Aug 12, 2026
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Aug 12, 2026

Monopar Reports Q2 2026 Net Loss of $5.3 Million - Quiver Quantitative

Aug 12, 2026
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Aug 12, 2026

Monopar Therapeutics reports Q2 2026: $5.3M net loss, $134.3M cash on hand - TradingView

Aug 12, 2026
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Aug 12, 2026

Monopar Therapeutics 2Q 2026: Net income $(5.31M), EPS $(0.62) — 10-Q Summary - TradingView

Aug 12, 2026
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Aug 12, 2026

Monopar Therapeutics (MNPR) deepens R&D spend but retains $134M cash runway - Stock Titan

Aug 12, 2026
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Aug 08, 2026

Monopar Therapeutics (NASDAQ:MNPR) Upgraded at Wall Street Zen - MarketBeat

Aug 08, 2026
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Aug 07, 2026

Monopar Therapeutics Inc. expected to post a loss of 62 cents a shareEarnings Preview - TradingView

Aug 07, 2026
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Aug 07, 2026

Bank of New York Mellon Corp Has $4.31 Million Position in Monopar Therapeutics Inc. $MNPR - MarketBeat

Aug 07, 2026
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Aug 06, 2026

Why is Monopar Therapeutics stock up today? Resistance levels in focus - tradersunion.com

Aug 06, 2026
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Aug 06, 2026

Monopar Therapeutics (NASDAQ:MNPR) Sets New 1-Year HighWhat's Next? - marketbeat.com

Aug 06, 2026
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Aug 05, 2026

MNPR Q2'26 Earnings: EPS estimate is (0.66) USD - TradingView

Aug 05, 2026
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Aug 04, 2026

Monopar Therapeutics stock approaches $125.77 resistance as bullish momentum drives gains - Traders Union

Aug 04, 2026
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Aug 04, 2026

Monopar Therapeutics (MNPR) Projected to Post Earnings on Tuesday - MarketBeat

Aug 04, 2026
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Aug 03, 2026

Monopar Therapeutics stock closes near session high as buyers regain control - tradersunion.com

Aug 03, 2026
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Aug 03, 2026

Monopar Therapeutics (MNPR) Gains 3% as Stock Holds Above Key SupportInvestment Factor - vinanet.vn

Aug 03, 2026
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Aug 02, 2026

MNPR Q1 2026 Earnings: Narrower-Than-Expected Loss Beats Estimates as Pipeline Progress ContinuesEarnings Season Outlook - vinanet.vn

Aug 02, 2026
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Aug 01, 2026

Monopar Therapeutics (MNPR) Slides 5.5% as Biotech Stock Tests Key Support at $102.93Relative Volume - vinanet.vn

Aug 01, 2026
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Jul 31, 2026

Why is Monopar Therapeutics stock down today? Key support levels to watch - Traders Union

Jul 31, 2026

Monopar Therapeutics Inc Stock (MNPR) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Monopar Therapeutics Inc Stock (MNPR) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
RIOUX PATRICE
Acting Chief Medical Officer
Aug 26 '26
Sale
111.26
1
111
5,065
Tsuchimoto Kim R
Director
Aug 26 '26
Sale
111.39
4,090
455,567
7,396
Anderson Raymond
Director
Aug 25 '26
Sale
111.77
3,142
351,189
23,751
$118.88
price down icon 2.14%
$103.73
price down icon 7.07%
$60.78
price down icon 1.63%
$235.50
price up icon 0.88%
ONC ONC
$365.45
price down icon 1.97%
$206.34
price down icon 6.53%
Cap:     |  Volume (24h):