346.58
price up icon2.84%   9.56
after-market After Hours: 346.58
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Krystal Biotech Inc stock is traded at $346.58, with a volume of 407.79K. It is up +2.84% in the last 24 hours and up +2.22% over the past month. Krystal Biotech Inc is an integrated, commercial-stage biotechnology company focused on the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs. The company uses its patented HSV-1-based gene therapy platform to create vectors that deliver therapeutic transgenes to target cells. It possesses exclusive rights to develop, manufacture, and commercialize VYJUVEK internationally. The company operates as one operating segment focused on pharmaceutical products and manufactures, markets, and sells VYJUVEK in the United States and markets and sells VYJUVEK in the European Union, and Japan.
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Previous Close:
$337.02
Open:
$337.44
24h Volume:
407.79K
Relative Volume:
1.02
Market Cap:
$10.26B
Revenue:
$417.30M
Net Income/Loss:
$225.03M
P/E Ratio:
46.32
EPS:
7.4815
Net Cash Flow:
$237.38M
1W Performance:
+4.31%
1M Performance:
+2.22%
6M Performance:
+32.38%
1Y Performance:
+137.87%
1-Day Range:
Value
$335.72
$348.03
1-Week Range:
Value
$330.06
$348.03
52-Week Range:
Value
$136.73
$382.54

Krystal Biotech Inc Stock (KRYS) Company Profile

Name
Name
Krystal Biotech Inc
Name
Phone
(412) 586-5830
Name
Address
2100 WHARTON STREET, PITTSBURGH, PA
Name
Employee
295
Name
Twitter
@KrystalBiotech
Name
Next Earnings Date
2026-08-03
Name
Latest SEC Filings
Name
KRYS's Discussions on Twitter

Compare KRYS vs VRTX, REGN, ARGX, MRNA, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
KRYS icon
KRYS
Krystal Biotech Inc
346.58 9.98B 417.30M 225.03M 237.38M 7.4815
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
548.05 136.93B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
834.04 85.11B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
1,039.78 64.95B 4.16B 1.29B 734.26M 19.58
MRNA icon
MRNA
Moderna Inc
145.13 53.23B 2.23B -3.19B -1.60B -8.1462
RVMD icon
RVMD
Revolution Medicines Inc
209.46 45.38B 742.00K -1.37B -1.07B -7.0731

Krystal Biotech Inc Stock (KRYS) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-27-26 Initiated Wolfe Research Peer Perform
Jan-06-26 Upgrade Citigroup Neutral → Buy
Mar-05-25 Initiated Jefferies Buy
Aug-06-24 Downgrade Citigroup Buy → Neutral
Nov-20-23 Initiated Goldman Buy
Oct-24-23 Initiated Cantor Fitzgerald Overweight
Oct-12-23 Initiated Citigroup Buy
Sep-07-23 Initiated Berenberg Buy
Apr-18-23 Initiated Stifel Buy
Feb-28-23 Upgrade Goldman Neutral → Buy
Aug-25-22 Downgrade Goldman Buy → Neutral
Jan-18-22 Initiated BofA Securities Buy
Jul-20-21 Upgrade Goldman Neutral → Buy
Sep-18-20 Initiated B. Riley FBR Buy
Jun-04-20 Initiated Evercore ISI Outperform
Sep-24-19 Initiated Goldman Neutral
Aug-06-19 Reiterated H.C. Wainwright Buy
Jun-24-19 Reiterated Chardan Capital Markets Buy
Jun-24-19 Reiterated H.C. Wainwright Buy
May-30-19 Initiated Guggenheim Buy
Sep-11-18 Initiated Cantor Fitzgerald Overweight
View All

Krystal Biotech Inc Stock (KRYS) Latest News

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Aug 21, 2026

Vertex Pharmaceuticals Inc. stock outperforms competitors on strong trading day - MarketWatch

Aug 21, 2026
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Aug 20, 2026

KRYS Stock Rallies On Upbeat Earnings: Jefferies Ups Price Target On Sustained Vyjuvek Optimism - Stocktwits

Aug 20, 2026
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Aug 18, 2026

Krystal Biotech Inc (MIL:1KRYS) Stock Price, Trades & News - GuruFocus

Aug 18, 2026
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Aug 17, 2026

Krystal Biotech, Inc. (KRYS) Stock Analysis: Exploring The 15.87% Upside Potential - DirectorsTalk Interviews

Aug 17, 2026
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Aug 17, 2026

Krystal Biotech Insider Sold Shares Worth $8,227,953, According to a Recent SEC Filing - marketscreener.com

Aug 17, 2026
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Aug 16, 2026

State of Wyoming Buys New Stake in Krystal Biotech, Inc. $KRYS - MarketBeat

Aug 16, 2026
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Aug 15, 2026

Should Surging Vyjuvek-Driven Earnings Reshape How Krystal Biotech (KRYS) Investors View Its Risk Profile? - simplywall.st

Aug 15, 2026
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Aug 15, 2026

Krystal Biotech (KRYS) Has a New Rating from RBC Capital - The Globe and Mail

Aug 15, 2026
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Aug 15, 2026

Krystal Biotech (NASDAQ:KRYS) Upgraded to "Moderate Buy" at Royal Bank Of Canada - MarketBeat

Aug 15, 2026
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Aug 15, 2026

Krystal Biotech (KRYS) Director Dino Rossi Sells 25,000 Shares - GuruFocus

Aug 15, 2026
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Aug 14, 2026

Krystal Biotech(KRYS.US) Director Sells US$8.23 Million in Common Stock - Moomoo

Aug 14, 2026
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Aug 14, 2026

Krystal Biotech (KRYS) Advances 1.2% to $332.27, Holding Ground Above Key SupportAggressive Growth Picks - vinanet.vn

Aug 14, 2026
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Aug 14, 2026

Krystal Biotech (NASDAQ:KRYS) director Dino Rossi sells $8.2m shares - Investing.com Australia

Aug 14, 2026
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Aug 14, 2026

Dino Rossi Sells 25,000 Shares of Krystal Biotech (NASDAQ:KRYS) Stock - MarketBeat

Aug 14, 2026
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Aug 14, 2026

Krystal Biotech, Inc. SEC Filing (Aug 14, 2026) - Stock Titan

Aug 14, 2026
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Aug 14, 2026

Vertex Pharmaceuticals Just Hit an All-Time High. Here's Why the Biotech Stock Could Soar Even More - The Globe and Mail

Aug 14, 2026
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Aug 14, 2026

RBC Capital Initiates Krystal Biotech(KRYS.US) With Buy Rating, Announces Target Price $400 - moomoo.com

Aug 14, 2026
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Aug 14, 2026

KRYS Looks 0.5% Undervalued on GF Value™ - GuruFocus

Aug 14, 2026
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Aug 14, 2026

Krystal Biotech Seen Positioned for Further Gains on Vyjuvek, Pipeline Readouts, RBC Says - marketscreener.com

Aug 14, 2026
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Aug 14, 2026

KRYS Initiates Coverage by RBC Capital -- Rating Set to Outperfo - GuruFocus

Aug 14, 2026
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Aug 14, 2026

Krystal Bio wins bullish view at RBC Capital Markets (KRYS) - Seeking Alpha

Aug 14, 2026
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Aug 14, 2026

Here Are Friday’s Top Wall Street Analyst Research Calls: Cinemark, Digital Realty, Fox Corporation, Krystal Biotech, LTC Properties, Roku, Sandisk, T-Mobile US, Wayfair, and More - Yahoo Finance

Aug 14, 2026
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Aug 14, 2026

RBC Initiates Krystal Biotech at Outperform, With $400 Price Target - marketscreener.com

Aug 14, 2026
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Aug 13, 2026

KRYSTAL BIOTECH, INC. : RBC INITIATES COVERAGE WITH OUTPERFORM RATING; TARGET PRICE $400 - Bitget

Aug 13, 2026
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Aug 13, 2026

Krystal Biotech (KRYS) Earnings And Pipeline Progress Put Valuation Back In Focus - Sahm

Aug 13, 2026
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Aug 12, 2026

Krystal Biotech, Inc. (KRYS) Stock forecasts - Yahoo Finance UK

Aug 12, 2026
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Aug 12, 2026

Wolfe Research Maintains Krystal Biotech(KRYS.US) With Hold Rating - Moomoo

Aug 12, 2026
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Aug 11, 2026

Trading Systems Reacting to (KRYS) Volatility - news.stocktradersdaily.com

Aug 11, 2026
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Aug 11, 2026

Bank of America Corp DE Increases Stock Position in Krystal Biotech, Inc. $KRYS - MarketBeat

Aug 11, 2026
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Aug 10, 2026

Krystal Biotech (KRYS) Q2 2026 Earnings Call Transcript - The Globe and Mail

Aug 10, 2026
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Aug 10, 2026

If You Invested $1000 In Krystal Biotech Stock 5 Years Ago, You Would Have This Much Today - Benzinga

Aug 10, 2026
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Aug 10, 2026

Renaissance Technologies LLC Has $2.48 Million Stock Position in Krystal Biotech, Inc. $KRYS - MarketBeat

Aug 10, 2026
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Aug 10, 2026

Krystal Biotech, Inc. (KRYS) Stock Analysis: Exploring a 17% Potential Upside in the Biotech Sector - DirectorsTalk Interviews

Aug 10, 2026
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Aug 10, 2026

Krystal Biotech (KRYS) Stock May Be Fully Valued After Its 5x Run - Yahoo Finance

Aug 10, 2026
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Aug 09, 2026

Krystal Biotech Inc (KRYS) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Aug 09, 2026
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Aug 06, 2026

Krystal Biotech (NASDAQ:KRYS) Upgraded at Chardan Capital - MarketBeat

Aug 06, 2026
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Aug 06, 2026

Krystal Biotech, Inc. (KRYS) Stock Forecasts - Yahoo Finance

Aug 06, 2026
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Aug 06, 2026

California State Teachers Retirement System Has $6.76 Million Holdings in Krystal Biotech, Inc. $KRYS - marketbeat.com

Aug 06, 2026
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Aug 05, 2026

Krystal Biotech, Inc. 2026 Q2ResultsEarnings Call Presentation (NASDAQ:KRYS) 2026-08-05 - Seeking Alpha

Aug 05, 2026
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Aug 04, 2026

Krystal Q2 Earnings & Sales Beat Estimates, Pipeline in Focus - Yahoo Finance

Aug 04, 2026
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Aug 04, 2026

Citi Maintains Krystal Biotech(KRYS.US) With Buy Rating, Raises Target Price to $386 - Moomoo

Aug 04, 2026
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Aug 04, 2026

Krystal Biotech, Inc. Q2 2026 Earnings Call Summary - Yahoo Finance

Aug 04, 2026
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Aug 04, 2026

Brokers Issue Forecasts for Krystal Biotech FY2026 Earnings - MarketBeat

Aug 04, 2026
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Aug 04, 2026

Krystal Biotech Inc at TD Cowen Healthcare Conference Transcript - GuruFocus

Aug 04, 2026
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Aug 04, 2026

Krystal Biotech Inc at Bank of America Global Healthcare Conference Transcript - GuruFocus

Aug 04, 2026
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Aug 04, 2026

Krystal Biotech Inc (KRYS) (Q2 2026) Earnings Call Highlights: VYJUVEK Sales Surge 24% as ... By GuruFocus - Investing.com Canada

Aug 04, 2026
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Aug 03, 2026

Krystal Biotech Inc (KRYS) (Q2 2026) Earnings Call Highlights: V - GuruFocus

Aug 03, 2026
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Aug 03, 2026

Is Krystal Biotech (KRYS) Overvalued After Q2 Earnings Beat? EPS of $1.85 & Revenue of $119.2M; GF Score: 54/100 - GuruFocus

Aug 03, 2026
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Aug 03, 2026

Why Is Krystal Biotech (KRYS) Dropping 7.0%? - AlphaStreet

Aug 03, 2026
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Aug 03, 2026

Krystal Biotech stock falls 7% on revenue miss despite earnings beat - Investing.com South Africa

Aug 03, 2026
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Aug 03, 2026

krystal biotech vyjuvek revenue rises 24 percent - grafa.com

Aug 03, 2026

Krystal Biotech Inc Stock (KRYS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$61.31
price up icon 1.21%
$125.77
price up icon 0.55%
$116.57
price up icon 5.12%
$236.22
price up icon 3.02%
ONC ONC
$374.47
price up icon 1.44%
$209.46
price down icon 1.07%
Cap:     |  Volume (24h):