299.45
price down icon1.57%   -4.78
pre-market  Pre-market:  301.10   1.65   +0.55%
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Krystal Biotech Inc stock is traded at $299.45, with a volume of 162.21K. It is down -1.57% in the last 24 hours and up +8.52% over the past month. Krystal Biotech Inc is an integrated, commercial-stage biotechnology company focused on the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs. The company uses its patented HSV-1-based gene therapy platform to create vectors that deliver therapeutic transgenes to target cells. It possesses exclusive rights to develop, manufacture, and commercialize VYJUVEK internationally. The company operates as one operating segment focused on pharmaceutical products and manufactures, markets, and sells VYJUVEK in the United States and markets and sells VYJUVEK in the European Union, and Japan.
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Previous Close:
$304.23
Open:
$305.1
24h Volume:
162.21K
Relative Volume:
0.57
Market Cap:
$8.83B
Revenue:
$389.13M
Net Income/Loss:
$204.83M
P/E Ratio:
43.75
EPS:
6.8443
Net Cash Flow:
$188.91M
1W Performance:
-2.23%
1M Performance:
+8.52%
6M Performance:
+41.24%
1Y Performance:
+139.01%
1-Day Range:
Value
$297.18
$309.41
1-Week Range:
Value
$286.00
$309.41
52-Week Range:
Value
$122.80
$319.48

Krystal Biotech Inc Stock (KRYS) Company Profile

Name
Name
Krystal Biotech Inc
Name
Phone
(412) 586-5830
Name
Address
2100 WHARTON STREET, PITTSBURGH, PA
Name
Employee
295
Name
Twitter
@KrystalBiotech
Name
Next Earnings Date
2026-05-04
Name
Latest SEC Filings
Name
KRYS's Discussions on Twitter

Compare KRYS vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
KRYS icon
KRYS
Krystal Biotech Inc
299.45 8.97B 389.13M 204.83M 188.91M 6.8443
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
434.52 110.03B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
638.88 67.37B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
806.46 50.76B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
297.45 40.12B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
151.56 32.68B 742.00K -1.37B -1.07B -7.0731

Krystal Biotech Inc Stock (KRYS) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-27-26 Initiated Wolfe Research Peer Perform
Jan-06-26 Upgrade Citigroup Neutral → Buy
Mar-05-25 Initiated Jefferies Buy
Aug-06-24 Downgrade Citigroup Buy → Neutral
Nov-20-23 Initiated Goldman Buy
Oct-24-23 Initiated Cantor Fitzgerald Overweight
Oct-12-23 Initiated Citigroup Buy
Sep-07-23 Initiated Berenberg Buy
Apr-18-23 Initiated Stifel Buy
Feb-28-23 Upgrade Goldman Neutral → Buy
Aug-25-22 Downgrade Goldman Buy → Neutral
Jan-18-22 Initiated BofA Securities Buy
Jul-20-21 Upgrade Goldman Neutral → Buy
Sep-18-20 Initiated B. Riley FBR Buy
Jun-04-20 Initiated Evercore ISI Outperform
Sep-24-19 Initiated Goldman Neutral
Aug-06-19 Reiterated H.C. Wainwright Buy
Jun-24-19 Reiterated Chardan Capital Markets Buy
Jun-24-19 Reiterated H.C. Wainwright Buy
May-30-19 Initiated Guggenheim Buy
Sep-11-18 Initiated Cantor Fitzgerald Overweight
View All

Krystal Biotech Inc Stock (KRYS) Latest News

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May 25, 2026

Krystal Biotech (KRYS) Investor Outlook: Robust Growth Prospects with 8.32% Potential Upside - DirectorsTalk Interviews

May 25, 2026
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May 25, 2026

Precision Trading with Krystal Biotech Inc. (KRYS) Risk Zones - Stock Traders Daily

May 25, 2026
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May 23, 2026

Krystal Biotech Inc at Bank of America Global Healthcare Conference Transcript - GuruFocus

May 23, 2026
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May 22, 2026

BofA Securities Maintains Krystal Biotech(KRYS.US) With Buy Rating, Announces Target Price $364 - Moomoo

May 22, 2026
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May 22, 2026

KRYS Reiterates by HC Wainwright & Co. -- Price Target Maintained at $310 - GuruFocus

May 22, 2026
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May 22, 2026

KRYS Technical Analysis | Trend, Signals & Chart Patterns | KRYSTAL BIOTECH INC (NASDAQ:KRYS) - ChartMill

May 22, 2026
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May 21, 2026

Krystal Biotech outlines $175M-$195M 2026 non-GAAP opex while targeting 6 data readouts before year-end - MSN

May 21, 2026
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May 20, 2026

Krystal Biotech, Inc. Files Form 8-K with SEC Detailing Company Information and Annual Meeting Results - Minichart

May 20, 2026
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May 20, 2026

Krystal Biotech Shareholders Approve Directors and Compensation - TipRanks

May 20, 2026
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May 19, 2026

The Bull Case For Krystal Biotech (KRYS) Could Change Following UK Vyjuvek Approval And Rising Profitability - Sahm

May 19, 2026
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May 19, 2026

Krystal Biotech Inc stock (US5012681064): HC Wainwright confirms Buy as UK clears VYJUVEK - AD HOC NEWS

May 19, 2026
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May 18, 2026

Krystal Biotech gains regulatory approval to sell gene therapy in the United Kingdom - The Business Journals

May 18, 2026
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May 18, 2026

Krystal Biotech Q1 earnings & sales beat estimates, pipeline in focus - MSN

May 18, 2026
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May 18, 2026

Krystal Biotech receives UK approval for gene therapy VYJUVEK By Investing.com - Investing.com South Africa

May 18, 2026
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May 18, 2026

Krystal Biotech receives UK approval for gene therapy VYJUVEK - Investing.com

May 18, 2026
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May 18, 2026

Krystal Biotech's (KRYS) Buy Rating Reaffirmed at HC Wainwright - MarketBeat

May 18, 2026
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May 18, 2026

Krystal Biotech Announces United Kingdom MHRA Approval of VYJUVEK® for the Treatment of Dystrophic Epidermolysis Bullosa - The Manila Times

May 18, 2026
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May 18, 2026

First UK genetic medicine for DEB lets some patients treat wounds at home - Stock Titan

May 18, 2026
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May 18, 2026

Krystal Biotech Price Target Maintained With a $310.00/Share by HC Wainwright & Co. - Moomoo

May 18, 2026
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May 18, 2026

Krystal Biotech, Inc. (KRYS) Stock Analysis: Strong Buy Ratings and Promising 5.38% Upside Potential - DirectorsTalk Interviews

May 18, 2026
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May 17, 2026

Krystal Biotech Inc stock (US5012681064): gene therapy player draws attention after shareholder meet - AD HOC NEWS

May 17, 2026
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May 16, 2026

VIRGINIA RETIREMENT SYSTEMS ET Al Grows Stock Holdings in Krystal Biotech, Inc. $KRYS - MarketBeat

May 16, 2026
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May 16, 2026

Assessing Krystal Biotech (KRYS) Valuation After First Quarter Earnings and EPS Growth - Sahm

May 16, 2026
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May 16, 2026

Krystal Biotech, Inc. (NASDAQ:KRYS) Given Average Recommendation of "Moderate Buy" by Analysts - MarketBeat

May 16, 2026
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May 16, 2026

Krystal Biotech (KRYS) Receives Approval for Innovative Wound Tr - GuruFocus

May 16, 2026
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May 15, 2026

KRYS: All proposals, including director elections and compensation policies, were approved - TradingView

May 15, 2026
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May 15, 2026

Krystal Biotech's Medicine to Treat Wounds in Dystrophic Epidermolysis Bullosa Gets Approval in UK - Moomoo

May 15, 2026
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May 15, 2026

Krystal Biotech Inc Annual Shareholders Meeting Transcript - GuruFocus

May 15, 2026
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May 15, 2026

Krystal Biotech Inc Phase 1/2 Clinical Trial of KB103 Final Update Call Transcript - GuruFocus

May 15, 2026
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May 15, 2026

Krystal Biotech Inc at TD Cowen Healthcare Conference Transcript - GuruFocus

May 15, 2026
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May 14, 2026

BofA Securities Maintains Krystal Biotech(KRYS.US) With Buy Rating - Moomoo

May 14, 2026
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May 14, 2026

Why is Krystal Biotech (KRYS) down 11.5% since last earnings report? - MSN

May 14, 2026
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May 14, 2026

Krystal Biotech, Inc. Stock 12‑Month Price Target Raised to $330.56, Implies 6% Upside - TradingView

May 14, 2026
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May 14, 2026

Krystal Biotech stock (US5012681064): Hits all-time high near $316 - AD HOC NEWS

May 14, 2026
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May 14, 2026

Technical Reactions to KRYS Trends in Macro Strategies - Stock Traders Daily

May 14, 2026
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May 13, 2026

Krystal Biotech stock hits all-time high at 315.68 USD By Investing.com - Investing.com India

May 13, 2026
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May 13, 2026

There May Be Underlying Issues With The Quality Of Krystal Biotech's (NASDAQ:KRYS) Earnings - simplywall.st

May 13, 2026
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May 13, 2026

Krystal Biotech stock hits all-time high at 315.68 USD - Investing.com

May 13, 2026
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May 11, 2026

This Profitable Biotech Stealthily Climbs Into A Buy Zone - Investor's Business Daily

May 11, 2026
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May 11, 2026

Krystal Biotech (NASDAQ:KRYS) Hits New 52-Week HighHere's Why - MarketBeat

May 11, 2026
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May 11, 2026

Krystal Biotech's (NASDAQ:KRYS) Earnings Are Of Questionable Quality - Moomoo

May 11, 2026
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May 11, 2026

Krystal Biotech (KRYS) Is Up 6.5% After Vyjuvek-Fueled Q1 Profit Jump And Investor Conference Update - Yahoo Finance

May 11, 2026
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May 11, 2026

Krystal Biotech, Inc. (KRYS) Stock Analysis: Strong Buy Ratings Signal Promising Upside - DirectorsTalk Interviews

May 11, 2026
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May 11, 2026

State of New Jersey Common Pension Fund D Reduces Stock Position in Krystal Biotech, Inc. $KRYS - MarketBeat

May 11, 2026
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May 11, 2026

symbol__ Stock Quote Price and Forecast - CNN

May 11, 2026
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May 11, 2026

Krystal Biotech (KRYS) Is Up 13.1% After Strong Q1 Earnings And FDA Nod For At-Home Vyjuvek Use – Has The Bull Case Changed? - Sahm

May 11, 2026
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May 10, 2026

Krystal Biotech: Vyjuvek Is Not The Primary Asset (NASDAQ:KRYS) - Seeking Alpha

May 10, 2026
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May 10, 2026

Krystal Biotech, Inc. $KRYS Shares Purchased by Principal Financial Group Inc. - MarketBeat

May 10, 2026
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May 09, 2026

A Look At Krystal Biotech (KRYS) Valuation After Vyjuvek Powered Q1 2026 Earnings Beat - simplywall.st

May 09, 2026
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May 09, 2026

KRYS Financials: Revenue Breakdown, Margins & Competitor Comparison - Intellectia AI

May 09, 2026
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May 09, 2026

Krystal Biotech (NASDAQ:KRYS) Combines Perfect Trend Template with High-Growth Momentum - ChartMill

May 09, 2026

Krystal Biotech Inc Stock (KRYS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$29.96
price down icon 2.98%
$106.24
price down icon 3.00%
$92.14
price up icon 1.33%
$54.50
price up icon 1.77%
ONC ONC
$310.25
price up icon 0.20%
$151.56
price down icon 1.41%
Cap:     |  Volume (24h):