Get the Stockscreener App
79.67
0.71%
0.56
Ionis Pharmaceuticals Inc stock is traded at $79.67, with a volume of 1.40M.
It is up +0.71% in the last 24 hours and down -2.02% over the past month.
Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.
See More
Previous Close:
$79.11
Open:
$79.88
24h Volume:
1.40M
Relative Volume:
0.60
Market Cap:
$12.90B
Revenue:
$705.14M
Net Income/Loss:
$-453.90M
P/E Ratio:
-26.21
EPS:
-3.04
Net Cash Flow:
$-551.29M
1W Performance:
-0.33%
1M Performance:
-2.02%
6M Performance:
+82.77%
1Y Performance:
+129.66%
1-Day Range:
$78.02
$80.21
1-Week Range:
$78.02
$80.21
52-Week Range:
$23.95
$83.61
Ionis Pharmaceuticals Inc Stock (IONS) Company Profile
Name
Ionis Pharmaceuticals Inc
Sector
Industry
Phone
(760) 931-9200
Address
2855 GAZELLE COURT, CARLSBAD, CA
Compare IONS with other stocks
| Stocks | Price | Market Cap | Revenue | Net Income | Cash Flow | EPS |
|---|---|---|---|---|---|---|
IONS
Ionis Pharmaceuticals Inc
|
79.67 | 12.81B | 705.14M | -453.90M | -551.29M | -3.04 |
|
VRTX
Vertex Pharmaceuticals Inc
|
452.13 | 115.03B | 11.74B | 3.68B | 3.34B | 14.19 |
|
REGN
Regeneron Pharmaceuticals Inc
|
776.31 | 81.12B | 14.25B | 4.58B | 3.88B | 41.77 |
|
ALNY
Alnylam Pharmaceuticals Inc
|
400.17 | 52.54B | 3.21B | 43.57M | 221.36M | 0.2405 |
|
ARGX
Argen X Se Adr
|
839.99 | 51.78B | 3.06B | 1.28B | 447.35M | 19.67 |
|
INSM
Insmed Inc
|
177.12 | 37.12B | 447.02M | -1.18B | -906.14M | -6.1812 |
Ionis Pharmaceuticals Inc Stock (IONS) Upgrades & Downgrades
| Date | Action | Analyst | Rating Change |
|---|---|---|---|
| Oct-08-25 | Upgrade | JP Morgan | Neutral → Overweight |
| Sep-26-25 | Upgrade | Goldman | Sell → Neutral |
| Sep-03-25 | Upgrade | BMO Capital Markets | Market Perform → Outperform |
| Jul-31-25 | Upgrade | Morgan Stanley | Equal-Weight → Overweight |
| Jul-01-25 | Upgrade | Barclays | Equal Weight → Overweight |
| Apr-07-25 | Initiated | H.C. Wainwright | Buy |
| Mar-31-25 | Initiated | Redburn Atlantic | Neutral |
| Aug-02-24 | Downgrade | BMO Capital Markets | Outperform → Market Perform |
| Jul-24-24 | Upgrade | Leerink Partners | Market Perform → Outperform |
| Jul-16-24 | Resumed | Jefferies | Buy |
| Jun-14-24 | Upgrade | Bernstein | Underperform → Mkt Perform |
| Apr-10-24 | Upgrade | Wolfe Research | Peer Perform → Outperform |
| Jan-02-24 | Upgrade | BofA Securities | Neutral → Buy |
| Oct-23-23 | Upgrade | BofA Securities | Underperform → Neutral |
| Sep-29-23 | Initiated | Raymond James | Strong Buy |
| Jul-31-23 | Upgrade | Citigroup | Neutral → Buy |
| Jun-07-23 | Resumed | Piper Sandler | Overweight |
| May-04-23 | Upgrade | Citigroup | Sell → Neutral |
| Mar-21-23 | Initiated | Bernstein | Underperform |
| Dec-21-22 | Downgrade | Morgan Stanley | Overweight → Equal-Weight |
| Sep-09-22 | Resumed | Morgan Stanley | Overweight |
| Jul-18-22 | Resumed | Oppenheimer | Outperform |
| Mar-31-22 | Resumed | Piper Sandler | Overweight |
| Mar-01-22 | Initiated | Citigroup | Sell |
| Mar-01-22 | Initiated | Guggenheim | Buy |
| Feb-01-22 | Downgrade | BofA Securities | Buy → Underperform |
| Dec-14-21 | Upgrade | William Blair | Mkt Perform → Outperform |
| May-07-21 | Upgrade | UBS | Sell → Neutral |
| Mar-01-21 | Upgrade | Barclays | Underweight → Equal Weight |
| Dec-16-20 | Initiated | UBS | Sell |
| Dec-15-20 | Upgrade | Cowen | Market Perform → Outperform |
| Sep-14-20 | Resumed | JP Morgan | Neutral |
| Sep-02-20 | Initiated | The Benchmark Company | Hold |
| Jun-01-20 | Resumed | Oppenheimer | Outperform |
| May-13-20 | Initiated | RBC Capital Mkts | Outperform |
| Mar-05-20 | Initiated | Citigroup | Buy |
| Dec-13-19 | Initiated | Oppenheimer | Outperform |
| Nov-13-19 | Initiated | BofA/Merrill | Buy |
| Nov-07-19 | Downgrade | Morgan Stanley | Equal-Weight → Underweight |
| Sep-10-19 | Upgrade | Bernstein | Mkt Perform → Outperform |
| Aug-08-18 | Reiterated | Stifel | Hold |
| Aug-07-18 | Reiterated | Stifel | Hold |
| May-08-18 | Downgrade | Evercore ISI | Outperform → In-line |
| Oct-06-17 | Resumed | Goldman | Sell |
| Aug-17-17 | Initiated | Evercore ISI | Outperform |
| Aug-09-17 | Reiterated | Stifel | Hold |
| Mar-10-17 | Downgrade | Goldman | Neutral → Sell |
| Dec-28-16 | Reiterated | BMO Capital Markets | Outperform |
| Dec-27-16 | Reiterated | Leerink Partners | Mkt Perform |
View All
Ionis Pharmaceuticals Inc Stock (IONS) Latest News
Stock Traders Buy High Volume of Ionis Pharmaceuticals Call Options (NASDAQ:IONS) - MarketBeat
Diversified Trust Co Invests $1.02 Million in Ionis Pharmaceuticals, Inc. $IONS - MarketBeat
Death Cross: Can Ionis Pharmaceuticals Inc stock continue upward trendMarket Movers & Reliable Breakout Forecasts - moha.gov.vn
Revenues Not Telling The Story For Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) - 富途牛牛
162,800 Shares in Ionis Pharmaceuticals, Inc. $IONS Bought by Capricorn Fund Managers Ltd - MarketBeat
Cns Specific Antisense Oligonucleotide MarketForecast - openPR.com
Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Given Consensus Rating of "Moderate Buy" by Brokerages - MarketBeat
Ionis Pharmaceuticals Sees Rapid Rise On RNA Drug Progress - Finimize
What Awaits These 4 Biotech Stocks That More Than Doubled in 2025 - Finviz
How Ionis Pharmaceuticals Inc. stock reacts to job market dataJuly 2025 Review & High Accuracy Trade Alerts - ulpravda.ru
Discipline and Rules-Based Execution in IONS Response - news.stocktradersdaily.com
Will Ionis Pharmaceuticals Inc. stock outperform international peers2025 Support & Resistance & Fast Entry High Yield Stock Tips - Улправда
Assenagon Asset Management S.A. Boosts Stock Position in Ionis Pharmaceuticals, Inc. $IONS - MarketBeat
cathie wood’s ARK stock trades highlight ionis pharma sale By Investing.com - Investing.com Canada
cathie wood’s ARK stock trades highlight ionis pharma sale - Investing.com
Dip Buying: How Ionis Pharmaceuticals Inc. stock reacts to job market dataFed Meeting & Weekly Top Performers Watchlists - Улправда
How Ionis Pharmaceuticals Inc. stock compares to industry benchmarksJuly 2025 Sentiment & Reliable Breakout Stock Forecasts - DonanımHaber
Will Ionis Pharmaceuticals Inc. stock gain from government policiesJuly 2025 Snapshot & Safe Swing Trade Setups - DonanımHaber
Can Ionis Pharmaceuticals Inc. stock continue upward trend2025 Growth vs Value & Daily Chart Pattern Signal Reports - DonanımHaber
Is Ionis Pharmaceuticals Inc. stock a safe investment in uncertain marketsForecast Cut & AI Optimized Trading Strategy Guides - Улправда
Ionis Pharmaceuticals Inc (HAM:ISI) Competitors 2025 - GuruFocus
Ionis Pharmaceuticals Inc Stock Operating Data - GuruFocus
Why Ionis Pharmaceuticals Inc. stock is a value investor pickIPO Watch & Proven Capital Preservation Methods - Улправда
Why retail investors favor Ionis Pharmaceuticals Inc. stockWeekly Risk Summary & Safe Entry Point Identification - Улправда
RBC Capital Maintains Ionis Pharmaceuticals (IONS) Outperform Recommendation - Nasdaq
How reliable is Ionis Pharmaceuticals Inc. (ISI) stock dividend growthStock Buyback Updates & Learn the Basics of Investing in 5 Days - Bollywood Helpline
RBC Capital Raises Price Target for Ionis Pharmaceuticals (IONS) to $95 | IONS Stock News - GuruFocus
RBC Raises Price Target on Ionis Pharmaceuticals to $95 From $82, Keeps Outperform Rating - marketscreener.com
Sicart Associates LLC Has $10.75 Million Stock Position in Ionis Pharmaceuticals, Inc. $IONS - MarketBeat
Ionis Pharmaceuticals stock price target raised to $95 from $82 at RBC Capital - Investing.com UK
EBITDA per share of Ionis Pharmaceuticals, Inc. – TRADEGATE:ISI - TradingView — Track All Markets
Ionis Pharmaceuticals (IONS): Leerink Partners Raises Price Targ - GuruFocus
Squarepoint Ops LLC Sells 170,978 Shares of Ionis Pharmaceuticals, Inc. $IONS - MarketBeat
GENESIS Pharma announces a new partnership with Otsuka Pharmaceutical Europe Ltd. for the commercial - pharmiweb.com
Ionis to hold third quarter 2023 financial results webcast - GuruFocus
Ionis Pharmaceuticals, Inc. $IONS Shares Sold by Hudson Bay Capital Management LP - MarketBeat
Marex Group plc Buys New Shares in Ionis Pharmaceuticals, Inc. $IONS - MarketBeat
Hudson Bay Capital Management LP Has $29.63 Million Holdings in Ionis Pharmaceuticals, Inc. $IONS - MarketBeat
Levels Update: Can Ionis Pharmaceuticals Inc stock sustain market leadershipJuly 2025 Review & Real-Time Volume Trigger Notifications - moha.gov.vn
Adage Capital Partners GP L.L.C. Raises Position in Ionis Pharmaceuticals, Inc. $IONS - MarketBeat
Ionis' Tryngolza Cuts Triglyceride Levels in Late-Stage Study - MSN
B of A Securities Maintains Ionis Pharmaceuticals (IONS) Buy Recommendation - Nasdaq
Ionis Pharmaceuticals (IONS) Price Target Raised by B of A Securities | IONS Stock News - GuruFocus
Ionis Pharmaceuticals (NASDAQ:IONS) Price Target Raised to $97.00 - MarketBeat
Angioedema Pipeline 2025: FDA Approvals and Clinical Trials - openPR.com
Ionis Pharmaceuticals, Inc. (IONS) Presents at The 67th American Society of Hematology (ASH) Annual MeetingSlideshow (NASDAQ:IONS) 2025-12-09 - Seeking Alpha
450,254 Shares in Ionis Pharmaceuticals, Inc. $IONS Acquired by Norges Bank - MarketBeat
Polycythemia Vera Market Positioned for Accelerated Development Through 2034, DelveInsight Finds | Novartis, Protagonist Therapeutics, Italfarmaco, Imago BioSciences, Silence Therapeutics, Ionis Pharm - Barchart.com
Multiple System Atrophy Market to Reach New Heights in Growth by 2034, DelveInsight Predicts | Ionis Pharma, Biohaven Pharma, Lundbeck A/S, Alterity Therapeutics, Theravance Biopharma, Brain Neuro - Barchart.com
Can Ionis Pharmaceuticals Stock Hold Up When Markets Turn? - Trefis
Has Ionis Pharmaceuticals Run Too Far After 135% Surge and Bullish DCF Outlook? - Yahoo Finance
Ionis Pharmaceuticals Inc Stock (IONS) Financials Data
Revenue
Net Income
Cash Flow
EPS
Ionis Pharmaceuticals Inc Stock (IONS) Insider Trading
| Insider Trading | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total |
|---|---|---|---|---|---|---|---|
| WENDER JOSEPH H | Director |
Dec 01 '25 |
Sale |
80.82 |
28,000 |
2,262,848 |
36,035 |
0.57%
Open in Yahoo
|
Open in Google
|
Open in Finviz
|
Open in MarketWatch
|
Open in EDGAR
|
Open in Reuters
Cap:
|
Volume (24h):