28.51
price up icon0.39%   0.11
pre-market  Pre-market:  29.69   1.18   +4.14%
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Ionis Pharmaceuticals Inc stock is traded at $28.51, with a volume of 950.54K. It is up +0.39% in the last 24 hours and down -13.37% over the past month. Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.
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Previous Close:
$28.40
Open:
$28.04
24h Volume:
950.54K
Relative Volume:
0.55
Market Cap:
$4.56B
Revenue:
$705.14M
Net Income/Loss:
$-453.90M
P/E Ratio:
-9.3783
EPS:
-3.04
Net Cash Flow:
$-551.29M
1W Performance:
-0.59%
1M Performance:
-13.37%
6M Performance:
-26.90%
1Y Performance:
-29.92%
1-Day Range:
Value
$27.90
$29.06
1-Week Range:
Value
$27.57
$29.06
52-Week Range:
Value
$23.95
$52.34

Ionis Pharmaceuticals Inc Stock (IONS) Company Profile

Name
Name
Ionis Pharmaceuticals Inc
Name
Phone
(760) 931-9200
Name
Address
2855 GAZELLE COURT, CARLSBAD, CA
Name
Employee
927
Name
Twitter
@ionispharma
Name
Next Earnings Date
2024-11-06
Name
Latest SEC Filings
Name
IONS's Discussions on Twitter

Compare IONS with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
IONS
Ionis Pharmaceuticals Inc
28.51 4.56B 705.14M -453.90M -551.29M -3.04
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
477.52 127.47B 11.02B -535.60M -978.00M -2.20
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
561.49 62.43B 14.20B 4.41B 3.54B 38.28
Biotechnology icon
ARGX
Argen X Se Adr
595.70 37.03B 2.19B 833.04M -1.28B 12.71
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
232.75 31.06B 2.25B -278.16M -42.59M -2.17
Biotechnology icon
ONC
Beigene Ltd Adr
229.22 26.16B 3.81B -644.79M -669.77M -6.24

Ionis Pharmaceuticals Inc Stock (IONS) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-07-25 Initiated H.C. Wainwright Buy
Mar-31-25 Initiated Redburn Atlantic Neutral
Aug-02-24 Downgrade BMO Capital Markets Outperform → Market Perform
Jul-24-24 Upgrade Leerink Partners Market Perform → Outperform
Jul-16-24 Resumed Jefferies Buy
Jun-14-24 Upgrade Bernstein Underperform → Mkt Perform
Apr-10-24 Upgrade Wolfe Research Peer Perform → Outperform
Jan-02-24 Upgrade BofA Securities Neutral → Buy
Oct-23-23 Upgrade BofA Securities Underperform → Neutral
Sep-29-23 Initiated Raymond James Strong Buy
Jul-31-23 Upgrade Citigroup Neutral → Buy
Jun-07-23 Resumed Piper Sandler Overweight
May-04-23 Upgrade Citigroup Sell → Neutral
Mar-21-23 Initiated Bernstein Underperform
Dec-21-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-09-22 Resumed Morgan Stanley Overweight
Jul-18-22 Resumed Oppenheimer Outperform
Mar-31-22 Resumed Piper Sandler Overweight
Mar-01-22 Initiated Citigroup Sell
Mar-01-22 Initiated Guggenheim Buy
Feb-01-22 Downgrade BofA Securities Buy → Underperform
Dec-14-21 Upgrade William Blair Mkt Perform → Outperform
May-07-21 Upgrade UBS Sell → Neutral
Mar-01-21 Upgrade Barclays Underweight → Equal Weight
Dec-16-20 Initiated UBS Sell
Dec-15-20 Upgrade Cowen Market Perform → Outperform
Sep-14-20 Resumed JP Morgan Neutral
Sep-02-20 Initiated The Benchmark Company Hold
Jun-01-20 Resumed Oppenheimer Outperform
May-13-20 Initiated RBC Capital Mkts Outperform
Mar-05-20 Initiated Citigroup Buy
Dec-13-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
Nov-07-19 Downgrade Morgan Stanley Equal-Weight → Underweight
Sep-10-19 Upgrade Bernstein Mkt Perform → Outperform
Aug-08-18 Reiterated Stifel Hold
Aug-07-18 Reiterated Stifel Hold
May-08-18 Downgrade Evercore ISI Outperform → In-line
Oct-06-17 Resumed Goldman Sell
Aug-17-17 Initiated Evercore ISI Outperform
Aug-09-17 Reiterated Stifel Hold
Mar-10-17 Downgrade Goldman Neutral → Sell
Dec-28-16 Reiterated BMO Capital Markets Outperform
Dec-27-16 Reiterated Leerink Partners Mkt Perform
View All

Ionis Pharmaceuticals Inc Stock (IONS) Latest News

pulisher
Apr 20, 2025

Is Ionis Pharmaceuticals (NASDAQ:IONS) Using Debt In A Risky Way? - simplywall.st

Apr 20, 2025
pulisher
Apr 18, 2025

Ionis Pharmaceuticals EVP Jenne Kyle sells $85,533 in stock - Investing.com Australia

Apr 18, 2025
pulisher
Apr 17, 2025

Ionis Pharmaceuticals EVP Jenne Kyle sells $85,533 in stock By Investing.com - Investing.com Canada

Apr 17, 2025
pulisher
Apr 17, 2025

Ionis Pharmaceuticals EVP Brian Birchler sells $19,291 in stock By Investing.com - Investing.com South Africa

Apr 17, 2025
pulisher
Apr 17, 2025

Ionis Pharmaceuticals EVP Joseph Baroldi sells $111,555 in stock By Investing.com - Investing.com South Africa

Apr 17, 2025
pulisher
Apr 17, 2025

Ionis Pharmaceuticals EVP Joseph Baroldi sells $111,555 in stock - Investing.com

Apr 17, 2025
pulisher
Apr 16, 2025

Lobbying Update: $90,000 of IONIS PHARMACEUTICALS INC. lobbying was just disclosed - Nasdaq

Apr 16, 2025
pulisher
Apr 16, 2025

Ionis to hold first quarter 2025 financial results webcast - BioSpace

Apr 16, 2025
pulisher
Apr 16, 2025

Ionis Q1 2025 Earnings Call: Key Date and Details for Investors Revealed - Stock Titan

Apr 16, 2025
pulisher
Apr 12, 2025

Ionis Pharmaceuticals (IONS) Sees Price Target Cut by Morgan Sta - GuruFocus

Apr 12, 2025
pulisher
Apr 12, 2025

Ionis Pharmaceuticals (IONS) Surges 8.9%: Is This an Indication of Further Gains? - MSN

Apr 12, 2025
pulisher
Apr 11, 2025

Polycythemia Vera Market to Show Remarkable Growth Trends from - openPR.com

Apr 11, 2025
pulisher
Apr 11, 2025

Global Antisense & RNAi Therapeutics Market to Witness Massive - openPR.com

Apr 11, 2025
pulisher
Apr 10, 2025

Acromegaly Pipeline 2025: Detailed Clinical Trials - openPR.com

Apr 10, 2025
pulisher
Apr 10, 2025

Amyotrophic Lateral Sclerosis Pipeline 2025: MOA and ROA - openPR.com

Apr 10, 2025
pulisher
Apr 10, 2025

Transthyretin Amyloid Cardiomyopathy Treatment Market Set - openPR.com

Apr 10, 2025
pulisher
Apr 09, 2025

Ionis at Needham Conference: Strategic Growth and Future Prospects By Investing.com - Investing.com UK

Apr 09, 2025
pulisher
Apr 08, 2025

Ionis Pharmaceuticals initiated with a Buy at H.C. Wainwright - MSN

Apr 08, 2025
pulisher
Apr 08, 2025

HC Wainwright & Co. Initiates Coverage of Ionis Pharmaceuticals (IONS) with Buy Recommendation - MSN

Apr 08, 2025
pulisher
Apr 07, 2025

Drugmaker Ionis Pharmaceuticals Garners Analyst Praise For 'Pipeline Depth' - Benzinga

Apr 07, 2025
pulisher
Apr 07, 2025

This Reddit Analyst Begins Coverage On A Bullish Note; Here Are Top 5 Initiations For Monday - Benzinga

Apr 07, 2025
pulisher
Apr 07, 2025

Ionis Pharma stock hits 52-week low at $26.65 amid market challenges - Investing.com

Apr 07, 2025
pulisher
Apr 07, 2025

H.C. Wainwright initiates coverage for Ionis Pharma with 'buy' rating citing pending drug launches - TradingView

Apr 07, 2025
pulisher
Apr 07, 2025

H.C. Wainwright initiated coverage on Ionis Pharma with a new price target - Quantisnow

Apr 07, 2025
pulisher
Apr 07, 2025

HC Wainwright Initiates Ionis Pharmaceuticals With Buy Rating, $45 Price Target - MarketScreener

Apr 07, 2025
pulisher
Apr 07, 2025

H.C. Wainwright sets Ionis stock Buy rating, $45 target By Investing.com - Investing.com UK

Apr 07, 2025
pulisher
Apr 07, 2025

Ionis Pharmaceuticals Enters Oversold Territory (IONS) - Nasdaq

Apr 07, 2025
pulisher
Apr 04, 2025

Hereditary Angioedema Pipeline: Over 20 Leading Companies - openPR.com

Apr 04, 2025
pulisher
Apr 03, 2025

Ionis to host expert panel discussion on sHTG - The Joplin Globe

Apr 03, 2025
pulisher
Apr 03, 2025

Leading Medical Experts Reveal Latest Insights on Severe HTG Treatment Landscape - Stock Titan

Apr 03, 2025
pulisher
Apr 02, 2025

Treatment-resistant Hypertension Market Growth Projections 2024-2034: DelveInsight Analysis | Idorsia Pharma, Ionis Pharma, KBP Biosciences, KBP Biosciences, Quantum Genomics - Barchart.com

Apr 02, 2025
pulisher
Apr 02, 2025

Biogen’s Investigational Tau-Targeting Therapy BIIB080 Receives FDA Fast Track Designation for the Treatment of Alzheimer’s Disease - Biogen

Apr 02, 2025
pulisher
Apr 02, 2025

10 Promising Biotech Stocks to Invest in (April 2025) - Securities.io

Apr 02, 2025
pulisher
Apr 01, 2025

Redburn Atlantic Initiates Coverage of Ionis Pharmaceuticals (IONS) with Neutral Recommendation - MSN

Apr 01, 2025
pulisher
Mar 31, 2025

Assessing Ionis Pharmaceuticals: Insights From 8 Financial Analysts - Benzinga

Mar 31, 2025
pulisher
Mar 31, 2025

Redburn Atlantic initiated coverage on Ionis Pharma with a new price target - Quantisnow

Mar 31, 2025
pulisher
Mar 31, 2025

Redburn Atlantic Initiates Ionis Pharmaceuticals at Neutral With $39 Price Target - MarketScreener

Mar 31, 2025
pulisher
Mar 31, 2025

Ionis to present at upcoming investor conferences - The Joplin Globe

Mar 31, 2025
pulisher
Mar 31, 2025

Redburn initiates Ionis stock with Neutral, sets $39 target - Investing.com India

Mar 31, 2025
pulisher
Mar 30, 2025

11 Best Gene Therapy Stocks to Buy According to Analysts - Insider Monkey

Mar 30, 2025
pulisher
Mar 30, 2025

IONS Out-Licenses ex-U.S. Rights for Rare Disease Drug Tryngolza to Sobi - MSN

Mar 30, 2025
pulisher
Mar 29, 2025

Ionis expands partnership with Sobi to include olezarsen commercialization outside the U.S. - MSN

Mar 29, 2025
pulisher
Mar 28, 2025

Catalyst (CPRX) Up 14.7% Since Last Earnings Report: Can It Continue? - Yahoo Finance

Mar 28, 2025
pulisher
Mar 28, 2025

RNA Biotechs: Current State And Outlook - Seeking Alpha

Mar 28, 2025
pulisher
Mar 27, 2025

Ionis and Sobi agree on olezarsen commercialisation - Yahoo

Mar 27, 2025
pulisher
Mar 26, 2025

Ionis licenses olezarsen to Sobi for global reach By Investing.com - Investing.com South Africa

Mar 26, 2025

Ionis Pharmaceuticals Inc Stock (IONS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$20.07
price up icon 0.15%
$69.51
price down icon 4.32%
$32.19
price down icon 1.26%
$25.22
price up icon 2.48%
$101.81
price up icon 3.09%
biotechnology ONC
$229.22
price down icon 0.76%
Cap:     |  Volume (24h):