loading
Ionis Pharmaceuticals Inc stock is traded at $34.11, with a volume of 1.40M. It is up +1.79% in the last 24 hours and up +4.06% over the past month. Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.
See More
Previous Close:
$33.51
Open:
$33.84
24h Volume:
1.40M
Relative Volume:
0.85
Market Cap:
$5.43B
Revenue:
$705.14M
Net Income/Loss:
$-453.90M
P/E Ratio:
-11.22
EPS:
-3.04
Net Cash Flow:
$-551.29M
1W Performance:
+3.43%
1M Performance:
+4.06%
6M Performance:
-5.51%
1Y Performance:
-9.21%
1-Day Range:
Value
$33.43
$34.36
1-Week Range:
Value
$32.00
$34.36
52-Week Range:
Value
$23.95
$52.34

Ionis Pharmaceuticals Inc Stock (IONS) Company Profile

Name
Name
Ionis Pharmaceuticals Inc
Name
Phone
(760) 931-9200
Name
Address
2855 GAZELLE COURT, CARLSBAD, CA
Name
Employee
927
Name
Twitter
@ionispharma
Name
Next Earnings Date
2024-11-06
Name
Latest SEC Filings
Name
IONS's Discussions on Twitter

Compare IONS with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
IONS
Ionis Pharmaceuticals Inc
34.11 5.30B 705.14M -453.90M -551.29M -3.04
Biotechnology icon
ONC
Beone Medicines Ltd Adr
245.93 25.76B 3.81B -644.79M -669.77M -6.24
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
445.43 114.53B 11.10B -988.90M -1.26B -3.92
Biotechnology icon
AKTX
Akari Therapeutics Plc Adr
1.415 40.54M 0 0 0 0.00
Biotechnology icon
VRNA
Verona Pharma Plc Adr
84.10 6.44B 0 -153.72M -103.81M -2.00
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
490.81 65.13B 14.09B 4.50B 2.96B 39.28

Ionis Pharmaceuticals Inc Stock (IONS) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-07-25 Initiated H.C. Wainwright Buy
Mar-31-25 Initiated Redburn Atlantic Neutral
Aug-02-24 Downgrade BMO Capital Markets Outperform → Market Perform
Jul-24-24 Upgrade Leerink Partners Market Perform → Outperform
Jul-16-24 Resumed Jefferies Buy
Jun-14-24 Upgrade Bernstein Underperform → Mkt Perform
Apr-10-24 Upgrade Wolfe Research Peer Perform → Outperform
Jan-02-24 Upgrade BofA Securities Neutral → Buy
Oct-23-23 Upgrade BofA Securities Underperform → Neutral
Sep-29-23 Initiated Raymond James Strong Buy
Jul-31-23 Upgrade Citigroup Neutral → Buy
Jun-07-23 Resumed Piper Sandler Overweight
May-04-23 Upgrade Citigroup Sell → Neutral
Mar-21-23 Initiated Bernstein Underperform
Dec-21-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-09-22 Resumed Morgan Stanley Overweight
Jul-18-22 Resumed Oppenheimer Outperform
Mar-31-22 Resumed Piper Sandler Overweight
Mar-01-22 Initiated Citigroup Sell
Mar-01-22 Initiated Guggenheim Buy
Feb-01-22 Downgrade BofA Securities Buy → Underperform
Dec-14-21 Upgrade William Blair Mkt Perform → Outperform
May-07-21 Upgrade UBS Sell → Neutral
Mar-01-21 Upgrade Barclays Underweight → Equal Weight
Dec-16-20 Initiated UBS Sell
Dec-15-20 Upgrade Cowen Market Perform → Outperform
Sep-14-20 Resumed JP Morgan Neutral
Sep-02-20 Initiated The Benchmark Company Hold
Jun-01-20 Resumed Oppenheimer Outperform
May-13-20 Initiated RBC Capital Mkts Outperform
Mar-05-20 Initiated Citigroup Buy
Dec-13-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
Nov-07-19 Downgrade Morgan Stanley Equal-Weight → Underweight
Sep-10-19 Upgrade Bernstein Mkt Perform → Outperform
Aug-08-18 Reiterated Stifel Hold
Aug-07-18 Reiterated Stifel Hold
May-08-18 Downgrade Evercore ISI Outperform → In-line
Oct-06-17 Resumed Goldman Sell
Aug-17-17 Initiated Evercore ISI Outperform
Aug-09-17 Reiterated Stifel Hold
Mar-10-17 Downgrade Goldman Neutral → Sell
Dec-28-16 Reiterated BMO Capital Markets Outperform
Dec-27-16 Reiterated Leerink Partners Mkt Perform
View All

Ionis Pharmaceuticals Inc Stock (IONS) Latest News

pulisher
May 30, 2025

Why Is Ionis Pharmaceuticals (IONS) Up 5.5% Since Last Earnings Report? - Yahoo Finance

May 30, 2025
pulisher
May 30, 2025

We Discuss Why Ionis Pharmaceuticals, Inc.'s (NASDAQ:IONS) CEO Compensation May Be Closely Reviewed - simplywall.st

May 30, 2025
pulisher
May 29, 2025

Transthyretin Amyloid Cardiomyopathy Treatment Market Deep Research ReportPfizer, Ionis Pharmaceuticals - openPR.com

May 29, 2025
pulisher
May 28, 2025

Type 2 Diabetes Pipeline 2025: Therapies Under Investigation, - openPR.com

May 28, 2025
pulisher
May 27, 2025

Ionis Pharmaceuticals’ SWOT analysis: RNA therapeutics firm faces pivotal year for stock - Investing.com

May 27, 2025
pulisher
May 26, 2025

Angioedema Treatment Market Insights and Forecast from 2025 - openPR.com

May 26, 2025
pulisher
May 26, 2025

Hereditary Angioedema Drugs Market 2034: EMA, PDMA, FDA - openPR.com

May 26, 2025
pulisher
May 23, 2025

Ionis’ olezarsen shows new promise with strong Phase III results - The Pharma Letter

May 23, 2025
pulisher
May 23, 2025

December 2027 Options Now Available For Ionis Pharmaceuticals (IONS) - Nasdaq

May 23, 2025
pulisher
May 22, 2025

Ionis reports success in olezarsen trial for high triglycerides - Yahoo

May 22, 2025
pulisher
May 22, 2025

Treatment-Resistant Hypertension Market: Epidemiology, - openPR.com

May 22, 2025
pulisher
May 22, 2025

Ionis Pharmaceuticals (NASDAQ:IONS) Earns Buy Rating from HC Wainwright - Defense World

May 22, 2025
pulisher
May 21, 2025

Ionis' Tryngolza Cuts Triglyceride Levels in Late-Stage Study - MSN

May 21, 2025
pulisher
May 21, 2025

Hereditary Angioedema Market Set to Grow Substantially Through - openPR.com

May 21, 2025
pulisher
May 21, 2025

Analysts Offer Insights on Healthcare Companies: Strata Skin Sciences (SSKN), Ionis Pharmaceuticals (IONS) and Maze Therapeutics, Inc. (MAZE) - The Globe and Mail

May 21, 2025
pulisher
May 21, 2025

Transcript : Ionis Pharmaceuticals, Inc. Presents at RBC Capital Markets Global Healthcare Conference 2025, May-21-2025 08 - marketscreener.com

May 21, 2025
pulisher
May 21, 2025

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Shares Purchased by Janus Henderson Group PLC - Defense World

May 21, 2025
pulisher
May 20, 2025

Ionis reports positive data from study of olezarsen for hypertriglyceridemia - Clinical Trials Arena

May 20, 2025
pulisher
May 20, 2025

Ionis Pharmaceuticals (IONS) Receives Buy Rating from HC Wainwri - GuruFocus

May 20, 2025
pulisher
May 20, 2025

Expert Outlook: Ionis Pharmaceuticals Through The Eyes Of 14 Analysts - Benzinga

May 20, 2025
pulisher
May 20, 2025

In Brief: Essence Raises Ionis Tryngolza Hypertriglyceridemia Filing Hopes - insights.citeline.com

May 20, 2025
pulisher
May 19, 2025

Ionis reports positive results for olezarsen in study By Investing.com - Investing.com South Africa

May 19, 2025
pulisher
May 19, 2025

Ionis reports positive results for olezarsen in study - Investing.com Australia

May 19, 2025
pulisher
May 19, 2025

Olezarsen Cuts Triglyceride Levels at 6 Months in Essence Study - HCPLive

May 19, 2025
pulisher
May 19, 2025

Ionis announces positive topline results from Essence study of olezarsen in people with moderately elevated triglycerides - BioSpace

May 19, 2025
pulisher
May 19, 2025

Spinal Muscular Atrophy Pipeline 2025: MOA and ROA Insights, Clinical Trials Status, and Key Companies Involved by DelveInsight | Genentech Inc, Chugai Pharma, Cytokinetics Inc., Ionis Pharma, Genzyme - Barchart.com

May 19, 2025
pulisher
May 19, 2025

Ionis Pharmaceuticals Says Olezarsen Trial Meets Primary Endpoint, All Key Secondary Endpoints - marketscreener.com

May 19, 2025
pulisher
May 19, 2025

Ionis Pharmaceuticals (IONS) Reports Positive Results from Olezarsen Study | IONS Stock News - GuruFocus

May 19, 2025
pulisher
May 19, 2025

Ionis announces positive topline results from Essence study of o - GuruFocus

May 19, 2025
pulisher
May 19, 2025

Ionis announces positive topline results from Essence study of olezarsen in people with moderately elevated triglycerides | IONS Stock News - GuruFocus

May 19, 2025
pulisher
May 18, 2025

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Stake Reduced by Comerica Bank - Defense World

May 18, 2025
pulisher
May 16, 2025

Drug developer stocks fall as companies navigate clinical roadblocks - BioWorld MedTech

May 16, 2025
pulisher
May 15, 2025

Beta thalassemia Market: Epidemiology, Therapies, Companies, - openPR.com

May 15, 2025
pulisher
May 14, 2025

Transcript : Ionis Pharmaceuticals, Inc. Presents at BofA Securities 2025 Healthcare Conference, May-14-2025 09 - marketscreener.com

May 14, 2025
pulisher
May 14, 2025

Familial Chylomicronemia Syndrome Drugs Market Size in 7MM - openPR.com

May 14, 2025
pulisher
May 14, 2025

Polycythemia Vera Drugs Market Size in 7MM is expected to grow at - openPR.com

May 14, 2025
pulisher
May 13, 2025

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Receives Consensus Recommendation of “Moderate Buy” from Analysts - Defense World

May 13, 2025
pulisher
May 11, 2025

Ionis Pharmaceuticals, Inc. (IONS): Among Billionaire Glenn Russell Dubin’s Stock Picks with Huge Upside Potential - Insider Monkey

May 11, 2025
pulisher
May 11, 2025

Billionaire Glenn Russell Dubin’s 10 Stock Picks with Huge Upside Potential - Insider Monkey

May 11, 2025
pulisher
May 09, 2025

Bennett C. Frank of Ionis Pharmaceuticals sells $222,113 in stock - MSN

May 09, 2025
pulisher
May 06, 2025

Angioedema Clinical Trial Pipeline Analysis Demonstrates 15+ Key Companies at the Horizon Expected to Transform the Treatment Paradigm, Assesses DelveInsight - Yahoo Finance

May 06, 2025
pulisher
May 06, 2025

Ionis to host 2025 virtual Annual Meeting of Stockholders | IONS Stock News - GuruFocus

May 06, 2025
pulisher
May 06, 2025

Ionis to host 2025 virtual Annual Meeting of Stockholders - Business Wire

May 06, 2025
pulisher
May 05, 2025

Spinocerebellar Ataxias Pipeline 2025: Comprehensive Clinical Trials and Therapies Analysis with Key MOA and ROA Insights by DelveInsight | Biogen Inc, BioXcel Corp, Celavie Biosciences, Ionis Pharma - Barchart.com

May 05, 2025
pulisher
May 05, 2025

Spinocerebellar Ataxias Pipeline 2025: Comprehensive - openPR.com

May 05, 2025
pulisher
May 05, 2025

Oligonucleotide Delivery System Market Key Players Analysis - openPR.com

May 05, 2025
pulisher
May 05, 2025

Analysts Just Made A Sizeable Upgrade To Their Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Forecasts - Yahoo Finance

May 05, 2025
pulisher
May 05, 2025

Ionis Pharmaceuticals targets $750M revenue for 2025 with multiple launches underway - MSN

May 05, 2025

Ionis Pharmaceuticals Inc Stock (IONS) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading
$1.15
price up icon 6.48%
$31.19
price up icon 3.48%
$584.61
price up icon 1.98%
$306.09
price up icon 0.50%
$4.5994
price up icon 2.21%
$490.81
price up icon 0.11%
Cap:     |  Volume (24h):