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Fulcrum Therapeutics Inc stock is traded at $6.77, with a volume of 60,276. It is down -1.88% in the last 24 hours and down -42.11% over the past month. Fulcrum Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing small molecules for genetically defined rare diseases. Its product candidate, Pociredir, is an oral small molecule designed to induce fetal hemoglobin (HbF) and is in clinical development for sickle cell disease (SCD). The company completed dosing in the Phase 1b PIONEER trial evaluating pociredir in adults with SCD and reported clinical data showing clinically relevant HbF induction and improvements in markers of hemolysis and anemia. The company has also generated a pipeline of clinical-stage and pre-clinical programs targeting the root causes of rare genetic diseases.
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Previous Close:
$6.92
Open:
$6.87
24h Volume:
60,276
Relative Volume:
0.06
Market Cap:
$452.88M
Revenue:
$80.00M
Net Income/Loss:
$-74.88M
P/E Ratio:
-5.7315
EPS:
-1.1812
Net Cash Flow:
$-60.38M
1W Performance:
-11.01%
1M Performance:
-42.11%
6M Performance:
-8.12%
1Y Performance:
+128.62%
1-Day Range:
Value
$6.72
$6.87
1-Week Range:
Value
$6.72
$8.00
52-Week Range:
Value
$2.315
$15.74

Fulcrum Therapeutics Inc Stock (FULC) Company Profile

Name
Name
Fulcrum Therapeutics Inc
Name
Phone
617-651-8851
Name
Address
26 LANDSDOWNE STREET, CAMBRIDGE, MA
Name
Employee
55
Name
Twitter
@fulcrumtx
Name
Next Earnings Date
2024-11-05
Name
Latest SEC Filings
Name
FULC's Discussions on Twitter

Compare FULC vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
FULC
Fulcrum Therapeutics Inc
6.80 460.87M 80.00M -74.88M -60.38M -1.1812
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
453.60 114.72B 12.07B 3.95B 3.19B 15.33
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
744.21 78.67B 14.34B 4.50B 3.77B 41.56
Biotechnology icon
ARGX
Argen X Se Adr
685.06 42.38B 4.16B 1.29B 734.26M 19.59
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
314.65 41.75B 3.71B 313.75M 465.38M 2.2571
Biotechnology icon
ONC
Beone Medicines Ltd Adr
282.62 31.33B 5.36B 287.73M 924.18M 2.5229

Fulcrum Therapeutics Inc Stock (FULC) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-12-26 Initiated JP Morgan Overweight
Nov-24-25 Initiated Truist Buy
Jul-29-25 Upgrade H.C. Wainwright Neutral → Buy
May-23-25 Upgrade Leerink Partners Market Perform → Outperform
May-15-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Sep-13-24 Downgrade H.C. Wainwright Buy → Neutral
Sep-12-24 Downgrade BofA Securities Neutral → Underperform
Sep-12-24 Downgrade Cantor Fitzgerald Overweight → Neutral
Sep-12-24 Downgrade Leerink Partners Outperform → Market Perform
Sep-12-24 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-12-24 Downgrade Stifel Buy → Hold
Sep-09-24 Upgrade BofA Securities Underperform → Neutral
May-20-24 Initiated Cantor Fitzgerald Overweight
Mar-13-24 Initiated RBC Capital Mkts Outperform
Sep-25-23 Initiated Goldman Neutral
Aug-23-23 Upgrade H.C. Wainwright Neutral → Buy
Aug-22-23 Upgrade Stifel Hold → Buy
May-04-23 Downgrade Goldman Buy → Neutral
Mar-10-23 Downgrade Credit Suisse Outperform → Neutral
Mar-10-23 Downgrade H.C. Wainwright Buy → Neutral
Mar-09-23 Downgrade Stifel Buy → Hold
Feb-28-23 Downgrade Morgan Stanley Overweight → Equal-Weight
Feb-24-23 Downgrade BofA Securities Neutral → Underperform
Nov-15-22 Initiated Goldman Buy
Mar-08-22 Initiated Oppenheimer Outperform
Mar-03-22 Upgrade BofA Securities Underperform → Neutral
Aug-11-21 Upgrade Morgan Stanley Equal-Weight → Overweight
Apr-26-21 Resumed Credit Suisse Outperform
Mar-22-21 Initiated Credit Suisse Outperform
Mar-02-21 Initiated Stifel Buy
Oct-16-20 Initiated Piper Sandler Overweight
Aug-12-20 Downgrade BofA Securities Neutral → Underperform
Aug-12-20 Reiterated H.C. Wainwright Buy
Aug-12-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Jun-19-20 Downgrade BofA/Merrill Buy → Neutral
Jun-17-20 Initiated BTIG Research Buy
Oct-03-19 Initiated H.C. Wainwright Buy
Aug-12-19 Initiated BofA/Merrill Buy
View All

Fulcrum Therapeutics Inc Stock (FULC) Latest News

pulisher
08:12 AM

MedicAlert Foundation, Sickle Cell Disease Association of America, Inc. (SCDAA), and Fulcrum Therapeutics Partner to Accelerate Emergency Department Access to Critical Care Information for People Living with Sickle Cell Disease - The Manila Times

08:12 AM
pulisher
08:00 AM

MedicAlert Foundation, Sickle Cell Disease Association of America, Inc. (SCDAA), and Fulcrum Therapeutics Partner to Accelerate Emergency Department Access to Critical Care Information for People Living with Sickle Cell Disease - GlobeNewswire Inc.

08:00 AM
pulisher
Mar 16, 2026

Fulcrum Therapeutics Touts PIONEER HbF Gains, Early VOC Signal; FDA Path and Accelerated Approval Talk - Yahoo Finance

Mar 16, 2026
pulisher
Mar 16, 2026

Short Interest in Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Rises By 19.7% - MarketBeat

Mar 16, 2026
pulisher
Mar 16, 2026

Boothbay Fund Management Increases Stake in Fulcrum Therapeutics - National Today

Mar 16, 2026
pulisher
Mar 16, 2026

Fulcrum Therapeutics, Inc. $FULC Shares Bought by Boothbay Fund Management LLC - MarketBeat

Mar 16, 2026
pulisher
Mar 15, 2026

Wall Street analysts think Fulcrum Therapeutics (FULC) could surge 58.47%: Read this before placing a bet - MSN

Mar 15, 2026
pulisher
Mar 15, 2026

219,488 Shares in Fulcrum Therapeutics, Inc. $FULC Bought by Braidwell LP - MarketBeat

Mar 15, 2026
pulisher
Mar 14, 2026

Suvretta Capital Management LLC Raises Holdings in Fulcrum Therapeutics, Inc. $FULC - MarketBeat

Mar 14, 2026
pulisher
Mar 14, 2026

Whats next for Fulcrum Therapeutics Inc stock2026 Winners & Losers & Free Technical Pattern Based Buy Signals - baoquankhu1.vn

Mar 14, 2026
pulisher
Mar 12, 2026

Aug Macro: What’s next for Fulcrum Therapeutics Inc. stock2026 EndofYear Setup & Free Verified High Yield Trade Plans - baoquankhu1.vn

Mar 12, 2026
pulisher
Mar 10, 2026

Fulcrum Therapeutics at Leerink Conference: Strategic Focus on Sickle Cell By Investing.com - Investing.com Canada

Mar 10, 2026
pulisher
Mar 10, 2026

FULC: Pivotal study planned after robust PIONEER results, with focus on severe sickle cell and U.S. launch - TradingView

Mar 10, 2026
pulisher
Mar 10, 2026

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Given Average Recommendation of "Moderate Buy" by Analysts - MarketBeat

Mar 10, 2026
pulisher
Mar 10, 2026

Fulcrum Therapeutics (FULC) Stock Analysis Report | Financials & Insights - Benzinga Japan

Mar 10, 2026
pulisher
Mar 09, 2026

Fulcrum Therapeutics stock may face pressure on Ipsen withdrawal, Stifel says - Investing.com Canada

Mar 09, 2026
pulisher
Mar 07, 2026

Why Fulcrum Therapeutics Inc. stock appeals to dividend seekersJuly 2025 Highlights & Daily Price Action Insights - Naître et grandir

Mar 07, 2026
pulisher
Mar 07, 2026

Bullish analyst sentiment on Fulcrum Therapeutics (FULC) following positive updates from Phase 1b PIONEER study - MSN

Mar 07, 2026
pulisher
Mar 07, 2026

Fulcrum Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - The Manila Times

Mar 07, 2026
pulisher
Mar 06, 2026

Fulcrum Therapeutics reports inducement grants under Nasdaq Listing Rule 5635(c)(4) - marketscreener.com

Mar 06, 2026
pulisher
Mar 06, 2026

Bull Run: Can Fulcrum Therapeutics Inc disrupt its industryJuly 2025 Price Swings & Reliable Trade Execution Plans - baoquankhu1.vn

Mar 06, 2026
pulisher
Mar 06, 2026

New Fulcrum hire gets 34,000 stock options with 4-year vesting - Stock Titan

Mar 06, 2026
pulisher
Mar 04, 2026

Fulcrum Therapeutics to Participate in the Leerink Partners Global Healthcare Conference - 富途牛牛

Mar 04, 2026
pulisher
Mar 04, 2026

Hedge Fund Moves: Is Fulcrum Therapeutics Inc part of any ETFJuly 2025 Reactions & Daily Profit Maximizing Tips - baoquankhu1.vn

Mar 04, 2026
pulisher
Mar 03, 2026

FULC Financials: Income Statement, Balance Sheet & Cash Flow - Stock Titan

Mar 03, 2026
pulisher
Mar 02, 2026

Fulcrum Therapeutics (NASDAQ:FULC) Stock Price Down 7.5%Here's Why - MarketBeat

Mar 02, 2026
pulisher
Feb 28, 2026

FULC Earning Date, Earning Analysis and Earning Prediction - Intellectia AI

Feb 28, 2026
pulisher
Feb 27, 2026

Winners Losers: Can Fulcrum Therapeutics Inc keep up with sector leadersBond Market & Stepwise Swing Trade Plans - baoquankhu1.vn

Feb 27, 2026
pulisher
Feb 27, 2026

What is HC Wainwright’s Forecast for FULC Q1 Earnings? - Defense World

Feb 27, 2026
pulisher
Feb 26, 2026

Fulcrum: Strong HbF Signal, Narrow TAM, Same 'Hold' Conclusion (NASDAQ:FULC) - Seeking Alpha

Feb 26, 2026
pulisher
Feb 26, 2026

Fulcrum Therapeutics, Inc. (FULC): Analyst Ratings Suggest 111% Upside Potential – Is It Time to Buy? - DirectorsTalk Interviews

Feb 26, 2026
pulisher
Feb 26, 2026

HC Wainwright Has Optimistic Outlook of FULC Q1 Earnings - MarketBeat

Feb 26, 2026
pulisher
Feb 26, 2026

FY2030 Earnings Forecast for FULC Issued By HC Wainwright - Defense World

Feb 26, 2026
pulisher
Feb 25, 2026

Fulcrum Therapeutics move lower ‘overdone,’ says Stifel - Yahoo Finance

Feb 25, 2026
pulisher
Feb 25, 2026

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Q4 2025 Earnings Call Transcript - Insider Monkey

Feb 25, 2026
pulisher
Feb 25, 2026

H.C. Wainwright Maintains Buy on FULC Fulcrum Therapeutics, Inc. Feb 24, 2026 - Meyka

Feb 25, 2026
pulisher
Feb 25, 2026

Analysts Offer Insights on Healthcare Companies: Fulcrum Therapeutics (FULC) and Palvella Therapeutics (PVLA) - The Globe and Mail

Feb 25, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics, Inc. Q4 2025 Earnings Call Summary - Yahoo Finance

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics stock falls as sickle cell trial misses target - Investing.com Australia

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics stock falls as sickle cell trial misses target By Investing.com - Investing.com Canada

Feb 24, 2026
pulisher
Feb 24, 2026

Leerink reiterates Fulcrum Therapeutics stock rating on SCD data By Investing.com - Investing.com Canada

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics shares fall on profit-taking, Oppenheimer says By Investing.com - Investing.com Canada

Feb 24, 2026
pulisher
Feb 24, 2026

BofA reiterates Fulcrum Therapeutics stock Underperform rating at $7 By Investing.com - Investing.com Canada

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics (NASDAQ:FULC) Shares Gap DownWhat's Next? - MarketBeat

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics Shares Surge on Promising Clinical Trial Data and Strong Financial Runway - NewsCase

Feb 24, 2026
pulisher
Feb 24, 2026

Positive Developments in Fulcrum Therapeutics (FULC) Boost Inves - GuruFocus

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics Q4 Earnings Call Highlights - MarketBeat

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics (FULC) Shares Experience Unexpected Decline - GuruFocus

Feb 24, 2026
pulisher
Feb 24, 2026

Fulcrum Therapeutics (FULC) Surpasses Expectations with Phase Ib Study Results - GuruFocus

Feb 24, 2026
pulisher
Feb 24, 2026

FULC: Pociredir at 20 mg achieved strong HbF induction and clinical benefit in severe sickle cell disease - TradingView

Feb 24, 2026
pulisher
Feb 24, 2026

Earnings call transcript: Fulcrum Therapeutics Q4 2025 reports progress in sickle cell treatment - Investing.com Australia

Feb 24, 2026

Fulcrum Therapeutics Inc Stock (FULC) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$45.72
price down icon 0.15%
$27.61
price down icon 0.65%
$52.30
price down icon 0.69%
$88.00
price down icon 2.24%
$144.22
price up icon 0.91%
biotechnology ONC
$282.24
price down icon 0.11%
Cap:     |  Volume (24h):