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Fulcrum Therapeutics Inc stock is traded at $3.65, with a volume of 2.30M. It is up +4.29% in the last 24 hours and up +4.29% over the past month. Fulcrum Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing small molecules for genetically defined rare diseases. Its product candidate, Pociredir, is an oral small molecule designed to induce fetal hemoglobin (HbF) and is in clinical development for sickle cell disease (SCD). The company completed dosing in the Phase 1b PIONEER trial evaluating pociredir in adults with SCD and reported clinical data showing clinically relevant HbF induction and improvements in markers of hemolysis and anemia. The company has also generated a pipeline of clinical-stage and pre-clinical programs targeting the root causes of rare genetic diseases.
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Previous Close:
$3.50
Open:
$3.47
24h Volume:
2.30M
Relative Volume:
0.99
Market Cap:
$243.21M
Revenue:
$80.00M
Net Income/Loss:
$-76.12M
P/E Ratio:
-3.1836
EPS:
-1.1465
Net Cash Flow:
$-63.88M
1W Performance:
+4.29%
1M Performance:
+4.29%
6M Performance:
-64.00%
1Y Performance:
-54.03%
1-Day Range:
Value
$3.46
$3.785
1-Week Range:
Value
$3.41
$3.785
52-Week Range:
Value
$2.83
$15.74

Fulcrum Therapeutics Inc Stock (FULC) Company Profile

Name
Name
Fulcrum Therapeutics Inc
Name
Phone
617-651-8851
Name
Address
26 LANDSDOWNE STREET, CAMBRIDGE, MA
Name
Employee
55
Name
Twitter
@fulcrumtx
Name
Next Earnings Date
2026-08-04
Name
Latest SEC Filings
Name
FULC's Discussions on Twitter

Compare FULC vs VRTX, REGN, ARGX, RVMD, ALNY

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
FULC icon
FULC
Fulcrum Therapeutics Inc
3.65 233.22M 80.00M -76.12M -63.88M -1.1465
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
485.65 123.36B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
676.69 71.18B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
860.55 53.68B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
186.16 38.09B 742.00K -1.37B -1.07B -7.0731
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
267.47 37.80B 4.29B 577.22M 641.34M 4.2086

Fulcrum Therapeutics Inc Stock (FULC) Upgrades & Downgrades

Date Action Analyst Rating Change
Jan-12-26 Initiated JP Morgan Overweight
Nov-24-25 Initiated Truist Buy
Jul-29-25 Upgrade H.C. Wainwright Neutral → Buy
May-23-25 Upgrade Leerink Partners Market Perform → Outperform
May-15-25 Upgrade Cantor Fitzgerald Neutral → Overweight
Sep-13-24 Downgrade H.C. Wainwright Buy → Neutral
Sep-12-24 Downgrade BofA Securities Neutral → Underperform
Sep-12-24 Downgrade Cantor Fitzgerald Overweight → Neutral
Sep-12-24 Downgrade Leerink Partners Outperform → Market Perform
Sep-12-24 Downgrade RBC Capital Mkts Outperform → Sector Perform
Sep-12-24 Downgrade Stifel Buy → Hold
Sep-09-24 Upgrade BofA Securities Underperform → Neutral
May-20-24 Initiated Cantor Fitzgerald Overweight
Mar-13-24 Initiated RBC Capital Mkts Outperform
Sep-25-23 Initiated Goldman Neutral
Aug-23-23 Upgrade H.C. Wainwright Neutral → Buy
Aug-22-23 Upgrade Stifel Hold → Buy
May-04-23 Downgrade Goldman Buy → Neutral
Mar-10-23 Downgrade Credit Suisse Outperform → Neutral
Mar-10-23 Downgrade H.C. Wainwright Buy → Neutral
Mar-09-23 Downgrade Stifel Buy → Hold
Feb-28-23 Downgrade Morgan Stanley Overweight → Equal-Weight
Feb-24-23 Downgrade BofA Securities Neutral → Underperform
Nov-15-22 Initiated Goldman Buy
Mar-08-22 Initiated Oppenheimer Outperform
Mar-03-22 Upgrade BofA Securities Underperform → Neutral
Aug-11-21 Upgrade Morgan Stanley Equal-Weight → Overweight
Apr-26-21 Resumed Credit Suisse Outperform
Mar-22-21 Initiated Credit Suisse Outperform
Mar-02-21 Initiated Stifel Buy
Oct-16-20 Initiated Piper Sandler Overweight
Aug-12-20 Downgrade BofA Securities Neutral → Underperform
Aug-12-20 Reiterated H.C. Wainwright Buy
Aug-12-20 Downgrade Morgan Stanley Overweight → Equal-Weight
Jun-19-20 Downgrade BofA/Merrill Buy → Neutral
Jun-17-20 Initiated BTIG Research Buy
Oct-03-19 Initiated H.C. Wainwright Buy
Aug-12-19 Initiated BofA/Merrill Buy
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Fulcrum Therapeutics Inc Stock (FULC) Latest News

pulisher
Jul 17, 2026

BlackRock Portfolio Management LLC discloses 6.0% holding in THERAPEUTICS INC (FULC) - Stock Titan

Jul 17, 2026
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Jul 16, 2026

Kaplan Fox Encourages Investors of Fulcrum Therapeutics, Inc. (NA - The National Law Review

Jul 16, 2026
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Jul 16, 2026

Form 4 Fulcrum Therapeutics Inc For: 15 July By Investing.com - Investing.com South Africa

Jul 16, 2026
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Jul 16, 2026

Kaplan Fox & Kilsheimer LLP Alerts Fulcrum Therapeutics, Inc. (NASDAQ: FULC) Investors to a Securities Investigation - NewMediaWire

Jul 16, 2026
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Jul 15, 2026

Kevin Tang buys $891k of Fulcrum Therapeutics stock - Investing.com

Jul 15, 2026
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Jul 15, 2026

Fulcrum Therapeutics, Inc. (FULC) gains Tang Capital as 10.4% shareholder - Stock Titan

Jul 15, 2026
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Jul 15, 2026

Fulcrum Therapeutics (FULC) holder adds 249,946 shares in open-market buys - Stock Titan

Jul 15, 2026
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Jul 15, 2026

Fulcrum Therapeutics (FULC) insider reports 6,663,383-share Tang Capital stake - Stock Titan

Jul 15, 2026
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Jul 10, 2026

Frontier tech research, news & data - MLQ.ai

Jul 10, 2026
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Jul 09, 2026

Fulcrum Therapeutics (FULC) loses 51% in 4 weeks, here's why a trend reversal may be around the corner - MSN

Jul 09, 2026
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Jul 08, 2026

Fulcrum Therapeutics (FULC) Slides 3.7% as Sellers Test Key Support Near $3.45Charm Flow - dars.gov.et

Jul 08, 2026
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Jul 03, 2026

Fulcrum Therapeutics Inc. (FULC) Q1 2026 Earnings: Narrower-than-Expected Loss Drives Positive Market ReactionRevenue Surprise History - dars.gov.et

Jul 03, 2026
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Jul 02, 2026

Fulcrum Therapeutics (FULC) director awarded 32,000 options at $3.66 - Stock Titan

Jul 02, 2026
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Jul 02, 2026

Fulcrum Therapeutics (FULC) director awarded 32,000 stock options - Stock Titan

Jul 02, 2026
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Jul 02, 2026

Fulcrum Therapeutics (FULC) director receives 32,000 stock options at $3.66 strike - Stock Titan

Jul 02, 2026
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Jul 02, 2026

Fulcrum Therapeutics (FULC) director granted 32,000 stock options at $3.66 strike - Stock Titan

Jul 02, 2026
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Jul 02, 2026

[Form 4] Fulcrum Therapeutics, Inc. Insider Trading Activity - Stock Titan

Jul 02, 2026
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Jul 02, 2026

Fulcrum Therapeutics | 4: Statement of changes in beneficial ownership of securities-Director King Rachel K. - Moomoo

Jul 02, 2026
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Jul 02, 2026

After plunging 21.5% in 4 weeks, here's why the trend might reverse for Fulcrum Therapeutics (FULC) - MSN

Jul 02, 2026
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Jun 30, 2026

Fulcrum Therapeutics | 8-K: Current report - Moomoo

Jun 30, 2026
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Jun 30, 2026

Insider Sell Alert: Alan Ezekowitz Sells 18,000 Shares of Fulcru - GuruFocus

Jun 30, 2026
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Jun 30, 2026

Fulcrum Therapeutics (FULC) director sells 18,000 shares under 10b5-1 plan - Stock Titan

Jun 30, 2026
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Jun 29, 2026

Fulcrum Therapeutics, Inc.(NasdaqGM:FULC) dropped from Russell Small Cap Comp Growth Benchmark - marketscreener.com

Jun 29, 2026
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Jun 29, 2026

Fulcrum Therapeutics, Inc.(NasdaqGM:FULC) dropped from Russell 2500 Growth Benchmark - marketscreener.com

Jun 29, 2026
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Jun 29, 2026

Fulcrum Therapeutics, Inc.(NasdaqGM:FULC) dropped from Russell 2000 Growth Benchmark - marketscreener.com

Jun 29, 2026
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Jun 29, 2026

Fulcrum Therapeutics, Inc.(NasdaqGM:FULC) dropped from Russell 3000E Growth Benchmark - marketscreener.com

Jun 29, 2026
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Jun 29, 2026

FULC Stock Crashes as Cancer Risk Forces Its Only Drug Program's End - Eastern Progress

Jun 29, 2026
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Jun 28, 2026

Price to sales forward of Fulcrum Therapeutics, Inc. – NASDAQ:FULC - TradingView

Jun 28, 2026
pulisher
Jun 28, 2026

Fulcrum Therapeutics, Inc.(NasdaqGM:FULC) dropped from Russell Microcap Growth Benchmark Index - marketscreener.com

Jun 28, 2026
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Jun 28, 2026

Price to book forward of Fulcrum Therapeutics, Inc. – NASDAQ:FULC - TradingView

Jun 28, 2026
pulisher
Jun 28, 2026

Fulcrum Therapeutics, Inc.(NasdaqGM:FULC) dropped from Russell 3000 Growth Benchmark - marketscreener.com

Jun 28, 2026
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Jun 28, 2026

Price to earnings forward of Fulcrum Therapeutics, Inc. – NASDAQ:FULC - TradingView

Jun 28, 2026
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Jun 27, 2026

Fulcrum Therapeutics (FULC) Stock Fair Value Moves Lower After Pociredir Exit - Yahoo Finance

Jun 27, 2026
pulisher
Jun 27, 2026

Fulcrum Therapeutics (FULC) Surges 5.26% as Biotech Momentum Builds, Testing Key ResistanceHigh Dividend Factor - dars.gov.et

Jun 27, 2026
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Jun 26, 2026

[144] Fulcrum Therapeutics, Inc. SEC Filing - Stock Titan

Jun 26, 2026
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Jun 26, 2026

Fulcrum Therapeutics, Inc. Actuals & Estimates (NASDAQ:FULC) - TradingView

Jun 26, 2026
pulisher
Jun 25, 2026

EcoR1, Oleg Nodelman disclose 9.0% stake in Fulcrum (NASDAQ: FULC) - Stock Titan

Jun 25, 2026
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Jun 25, 2026

EcoR1 Capital (FULC) reports shared control of 6.0M shares; 9.0% stake - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Fulcrum Therapeutics Shareholders Reaffirm Board and Governance Structure - TipRanks

Jun 25, 2026
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Jun 25, 2026

Fulcrum Therapeutics (FULC) details 2026 stockholder voting on directors and key proposals - Stock Titan

Jun 25, 2026
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Jun 25, 2026

Fulcrum Therapeutics Inc (FULC) Institutional Confidence - TradingKey

Jun 25, 2026
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Jun 24, 2026

Fulcrum Therapeutics (FULC) Advances 1.8% as Shares Test Resistance Near $4.12Growth ETF - dars.gov.et

Jun 24, 2026
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Jun 24, 2026

Fulcrum Therapeutics Inc (FULC) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 24, 2026
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Jun 23, 2026

Fulcrum plunges after discontinuing lead program - MSN

Jun 23, 2026
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Jun 20, 2026

Fulcrum Therapeutics, Inc. (NASDAQ: FULC) Faces Possible Securiti - The National Law Review

Jun 20, 2026
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Jun 19, 2026

Kaplan Fox Encourages Investors of Fulcrum Therapeutics, Inc. (NASDAQ: FULC) to Contact the Firm - The National Law Review

Jun 19, 2026
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Jun 19, 2026

Bronstein, Gewirtz & Grossman, LLC Initiates an Investigation into Allegations Against Fulcrum Therapeutics, Inc. (FULC) And Encourages Shareholders to Reach Out - ACCESS Newswire

Jun 19, 2026
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Jun 19, 2026

2026-06-19 | Bronstein, Gewirtz & Grossman, LLC Initiates an Investigation into Allegations Against Fulcrum Therapeutics, Inc. (FULC) And Encourages Shareholders to Reach Out | NDAQ:FULC | Press Release - Stockhouse

Jun 19, 2026
pulisher
Jun 18, 2026

Bronstein, Gewirtz & Grossman, LLC Announces an Investigation Against Fulcrum Therapeutics, Inc. (FULC) and Encourages Shareholders to Learn More About the Investigation - ACCESS Newswire

Jun 18, 2026
pulisher
Jun 18, 2026

Investors of Fulcrum Therapeutics, Inc. (NASDAQ: FULC) are Encouraged to Contact Kaplan Fox Regarding the Investigation of Potential Securities Law Violations - NewMediaWire

Jun 18, 2026
pulisher
Jun 18, 2026

Fulcrum Therapeutics Inc (FULC) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Jun 18, 2026

Fulcrum Therapeutics Inc Stock (FULC) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$108.32
price up icon 0.80%
$61.82
price down icon 2.11%
$34.51
price up icon 1.71%
$58.18
price down icon 0.60%
ONC ONC
$312.02
price down icon 1.70%
$267.47
price down icon 5.54%
Cap:     |  Volume (24h):