2.86
price down icon2.05%   -0.06
after-market After Hours: 2.86
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Pyxis Oncology Inc stock is traded at $2.86, with a volume of 609.44K. It is down -2.05% in the last 24 hours and down -6.54% over the past month. Pyxis Oncology Inc is a clinical-stage oncology company focused on developing therapies for patients with solid tumors, with an initial emphasis on head and neck squamous cell carcinoma. Its product candidate, micvotabart pelidotin (MICVO, formerly PYX-201), is an investigational antibody-drug conjugate that targets extradomain-B fibronectin (EDB+FN), a component of the tumor extracellular matrix that is expressed in tumors and minimally present in normal tissues. MICVO consists of a fully human monoclonal antibody linked to a microtubule inhibitor payload, designed to bind within the tumor microenvironment and release its payload to kill cancer cells directly, affect nearby cells through a bystander effect, and induce immunogenic cell death, supporting enhanced anti-tumor activity.
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Previous Close:
$2.92
Open:
$2.91
24h Volume:
609.44K
Relative Volume:
0.47
Market Cap:
$238.55M
Revenue:
$13.86M
Net Income/Loss:
$-81.74M
P/E Ratio:
-2.1939
EPS:
-1.3036
Net Cash Flow:
$-66.98M
1W Performance:
-14.11%
1M Performance:
-6.54%
6M Performance:
+100.00%
1Y Performance:
+38.83%
1-Day Range:
Value
$2.785
$2.92
1-Week Range:
Value
$2.785
$3.405
52-Week Range:
Value
$1.03
$5.55

Pyxis Oncology Inc Stock (PYXS) Company Profile

Name
Name
Pyxis Oncology Inc
Name
Phone
(617) 221-9059
Name
Address
321 HARRISON AVENUE, BOSTON
Name
Employee
56
Name
Twitter
Name
Next Earnings Date
2026-11-02
Name
Latest SEC Filings
Name
PYXS's Discussions on Twitter

Compare PYXS vs VRTX, REGN, MRNA, ARGX, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PYXS icon
PYXS
Pyxis Oncology Inc
2.86 238.55M 13.86M -81.74M -66.98M -1.3036
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
526.19 133.37B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
788.04 81.13B 14.92B 4.42B 3.79B 41.04
MRNA icon
MRNA
Moderna Inc
198.88 79.40B 2.23B -3.19B -1.60B -8.1462
ARGX icon
ARGX
Argen X Se Adr
959.49 60.03B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
204.97 43.93B 742.00K -1.37B -1.07B -7.0731

Pyxis Oncology Inc Stock (PYXS) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-03-25 Resumed Stifel Buy
Sep-04-25 Initiated Guggenheim Buy
Nov-21-24 Downgrade William Blair Outperform → Mkt Perform
Nov-08-24 Initiated Stephens Overweight
Aug-08-24 Initiated Stifel Buy
May-07-24 Resumed Jefferies Buy
Feb-09-24 Initiated BTIG Research Buy
Jan-23-24 Initiated Leerink Partners Outperform
Sep-05-23 Initiated RBC Capital Mkts Outperform
Nov-02-21 Initiated BofA Securities Neutral
Nov-02-21 Initiated Credit Suisse Outperform
Nov-02-21 Initiated Jefferies Buy
View All

Pyxis Oncology Inc Stock (PYXS) Latest News

pulisher
Sep 25, 2026

LifeSci Capital Maintains Pyxis Oncology(PYXS.US) With Buy Rating, Maintains Target Price $8 - Moomoo

Sep 25, 2026
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Sep 23, 2026

Pyxis Oncology stock falls 3.73 percent after trial update - AD HOC NEWS

Sep 23, 2026
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Sep 21, 2026

Pyxis Oncology Inc (PYXS) Key Financial Ratios – Valuation, Profitability & More - Value Research

Sep 21, 2026
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Sep 20, 2026

Pyxis Oncology, Inc.(NasdaqGS: PYXS) added to S&P Global BMI Index - marketscreener.com

Sep 20, 2026
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Sep 11, 2026

Pyxis Oncology Inc (NASDAQ: PYXS) Share Price, PYXS Stock News, PYXS Share Price & Updates - kalkine.com.au

Sep 11, 2026
pulisher
Sep 11, 2026

Pyxis Oncology: Setbacks Costing Nearly 2 Years Of Recovery (NASDAQ:PYXS) - Seeking Alpha

Sep 11, 2026
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Sep 11, 2026

PYXIS ONCOLOGY, INC. : WELLS FARGO RAISES TARGET PRICE TO $19 FROM $12 - webull.com

Sep 11, 2026
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Sep 11, 2026

Wells Fargo raises Pyxis Oncology stock price target on MICVO data By Investing.com - Investing.com South Africa

Sep 11, 2026
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Sep 11, 2026

Wedbush raises Pyxis Oncology stock price target on trial data By Investing.com - Investing.com South Africa

Sep 11, 2026
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Sep 10, 2026

Enterprise value to revenue forward of Pyxis Oncology, Inc. – NASDAQ:PYXS - TradingView

Sep 10, 2026
pulisher
Sep 10, 2026

Pyxis Oncology stock price target raised to $8 by H.C. Wainwright By Investing.com - Investing.com Australia

Sep 10, 2026
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Sep 10, 2026

Pyxis Oncology Stock Soars Over 5% Overnight: Here's What You Need to Know - webull.com

Sep 10, 2026
pulisher
Sep 10, 2026

Pyxis Oncology (NASDAQ: PYXS) to Launch Phase 3 Trial for MICVO in Mid-2027 Following Promising Phase 1 Results - Kalkine Media

Sep 10, 2026
pulisher
Sep 10, 2026

Pyxis Oncology stock price target raised to $8 by H.C. Wainwright - Investing.com Nigeria

Sep 10, 2026
pulisher
Sep 10, 2026

A Quick Look at Today's Ratings for Pyxis Oncology(PYXS.US), With a Forecast Between $6 to $19 - Moomoo

Sep 10, 2026
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Sep 10, 2026

Wells Fargo raises Pyxis Oncology stock price target on MICVO data - Investing.com Australia

Sep 10, 2026
pulisher
Sep 10, 2026

Wedbush raises Pyxis Oncology stock price target on trial data - Investing.com India

Sep 10, 2026
pulisher
Sep 10, 2026

Pyxis Oncology, Inc. (PYXS) Discusses MICVO Monotherapy Phase I Clinical Data in Head and Neck Squamous Cell CarcinomaSlideshow (NASDAQ:PYXS) 2026-09-10 - Seeking Alpha

Sep 10, 2026
pulisher
Sep 09, 2026

Pyxis Oncology Slides 7% as Analysts Flag Toxicity Concerns for Lead Cancer Drug - finance.biggo.com

Sep 09, 2026
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Sep 09, 2026

Pyxis Oncology Analyst Flags Key Safety Liabilities from Cancer Drug - Benzinga

Sep 09, 2026
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Sep 09, 2026

Wedbush Lifts Price Target on Pyxis Oncology to $8 From $6, Keeps Outperform Rating - marketscreener.com

Sep 09, 2026
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Sep 09, 2026

Pyxis Oncology shares fall 7% despite updated MICVO trial results - Yahoo Finance

Sep 09, 2026
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Sep 09, 2026

PYXS: MICVO showed strong efficacy and manageable safety in advanced head and neck cancer patients - TradingView

Sep 09, 2026
pulisher
Sep 09, 2026

Pyxis Oncology stock falls 7% despite positive trial data By Investing.com - Investing.com Canada

Sep 09, 2026
pulisher
Sep 09, 2026

Pyxis slides after new early-stage trial data for lead asset in head and neck cancer - TradingView

Sep 09, 2026
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Sep 09, 2026

Pyxis Oncology Reports 36% Response Rate in Phase 1 MICVO Study - marketscreener.com

Sep 09, 2026
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Sep 09, 2026

Pyxis Oncology Reports Promising MICVO Phase 1 Results - TipRanks

Sep 09, 2026
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Sep 09, 2026

Pyxis Oncology reports 36% cORR, 6.2‑month mPFS and 79% 12‑month OS probability for MICVO in 2L+ HNSCC - TradingView

Sep 09, 2026
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Sep 09, 2026

Head and neck cancer drug from Pyxis Oncology (PYXS) shows tumor responses ahead of 500-patient trial - stocktitan.net

Sep 09, 2026
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Sep 09, 2026

A cancer treatment showed disease control in 94% of trial patients. Pyxis plans a roughly 500-patient trial. - stocktitan.net

Sep 09, 2026
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Sep 09, 2026

PYXS: MICVO achieved rapid, deep responses and strong disease control in advanced head and neck cancer - TradingView

Sep 09, 2026
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Sep 09, 2026

Pyxis Oncology Announces Positive Updated Data from Phase 1 Monotherapy Study of Micvotabart Pelidotin (MICVO) in Second-Line and Beyond Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (2L+ R/M HNSCC) - marketscreener.com

Sep 09, 2026
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Sep 09, 2026

symbol__ Stock Quote Price and Forecast - CNN

Sep 09, 2026
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Sep 09, 2026

Pyxis Oncology Shares Gain 9.25% After HoursPyxis Oncology (NASDAQ:PYXS) - Benzinga

Sep 09, 2026
pulisher
Sep 08, 2026

Pyxis Oncology to present clinical data on cancer therapy By Investing.com - Investing.com South Africa

Sep 08, 2026
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Sep 08, 2026

Pyxis Oncology to present clinical data on cancer therapy - investing.com

Sep 08, 2026
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Sep 08, 2026

Updated cancer-drug data will be presented Sept. 9. A Memorial Sloan Kettering expert will join Pyxis Oncology. - Stock Titan

Sep 08, 2026
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Sep 08, 2026

Pyxis Oncology Names Thomas Civik CEO and Chairman Ahead of MICVO Milestones - citybiz

Sep 08, 2026
pulisher
Sep 08, 2026

Pyxis Oncology Appoints Thomas Civik as CEO and Chairman of the Board - Oncodaily

Sep 08, 2026
pulisher
Sep 08, 2026

Pyxis Oncology Names Thomas Civik CEO, Board Chairman - marketscreener.com

Sep 08, 2026
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Sep 08, 2026

Pyxis Oncology names Thomas Civik as permanent CEO and chairman By Investing.com - Investing.com Nigeria

Sep 08, 2026
pulisher
Sep 08, 2026

Pyxis Oncology, Inc. Announces Board Changes - marketscreener.com

Sep 08, 2026
pulisher
Sep 08, 2026

Pyxis Oncology, Inc. Announces Appointment of Thomas Civik to Chief Executive Officer, Effective September 4, 2026 - marketscreener.com

Sep 08, 2026
pulisher
Sep 08, 2026

Pyxis Oncology Elevates Thomas Civik to Permanent CEO - TipRanks

Sep 08, 2026
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Sep 08, 2026

Pyxis Oncology names Thomas Civik as permanent CEO and chairman - Investing.com India

Sep 08, 2026
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Sep 08, 2026

Pyxis Oncology Appoints Thomas Civik Chief Executive Officer and Chairman of the Board - manilatimes.net

Sep 08, 2026
pulisher
Sep 08, 2026

Pyxis Oncology (PYXS) CEO receives 2.5M options at $3.89 - Stock Titan

Sep 08, 2026

Pyxis Oncology Inc Stock (PYXS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$117.83
price down icon 3.06%
$35.80
price down icon 0.91%
$58.21
price down icon 0.14%
$255.96
price up icon 2.55%
ONC ONC
$360.85
price up icon 0.24%
$204.97
price up icon 2.56%
Cap:     |  Volume (24h):