1.635
price down icon3.24%   -0.065
 
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Pyxis Oncology Inc stock is traded at $1.635, with a volume of 80,767. It is down -3.24% in the last 24 hours and up +6.82% over the past month. Pyxis Oncology Inc is a clinical-stage oncology company focused on developing therapies for patients with solid tumors, with an initial emphasis on head and neck squamous cell carcinoma. Its product candidate, micvotabart pelidotin (MICVO, formerly PYX-201), is an investigational antibody-drug conjugate that targets extradomain-B fibronectin (EDB+FN), a component of the tumor extracellular matrix that is expressed in tumors and minimally present in normal tissues. MICVO consists of a fully human monoclonal antibody linked to a microtubule inhibitor payload, designed to bind within the tumor microenvironment and release its payload to kill cancer cells directly, affect nearby cells through a bystander effect, and induce immunogenic cell death, supporting enhanced anti-tumor activity.
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Previous Close:
$1.70
Open:
$1.68
24h Volume:
80,767
Relative Volume:
0.14
Market Cap:
$102.73M
Revenue:
$13.86M
Net Income/Loss:
$-79.62M
P/E Ratio:
-1.2739
EPS:
-1.2835
Net Cash Flow:
$-63.51M
1W Performance:
+11.90%
1M Performance:
+6.82%
6M Performance:
-55.05%
1Y Performance:
+79.78%
1-Day Range:
Value
$1.635
$1.7477
1-Week Range:
Value
$1.425
$1.84
52-Week Range:
Value
$0.89
$5.55

Pyxis Oncology Inc Stock (PYXS) Company Profile

Name
Name
Pyxis Oncology Inc
Name
Phone
(617) 221-9059
Name
Address
321 HARRISON AVENUE, BOSTON
Name
Employee
56
Name
Twitter
Name
Next Earnings Date
2026-03-24
Name
Latest SEC Filings
Name
PYXS's Discussions on Twitter

Compare PYXS vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
PYXS icon
PYXS
Pyxis Oncology Inc
1.635 106.81M 13.86M -79.62M -63.51M -1.2835
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
441.25 113.01B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
748.88 79.87B 14.34B 4.50B 3.77B 41.56
ARGX icon
ARGX
Argen X Se Adr
845.84 51.51B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
334.76 45.29B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
314.79 34.41B 5.36B 287.73M 924.18M 2.5229

Pyxis Oncology Inc Stock (PYXS) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-03-25 Resumed Stifel Buy
Sep-04-25 Initiated Guggenheim Buy
Nov-21-24 Downgrade William Blair Outperform → Mkt Perform
Nov-08-24 Initiated Stephens Overweight
Aug-08-24 Initiated Stifel Buy
May-07-24 Resumed Jefferies Buy
Feb-09-24 Initiated BTIG Research Buy
Jan-23-24 Initiated Leerink Partners Outperform
Sep-05-23 Initiated RBC Capital Mkts Outperform
Nov-02-21 Initiated BofA Securities Neutral
Nov-02-21 Initiated Credit Suisse Outperform
Nov-02-21 Initiated Jefferies Buy
View All

Pyxis Oncology Inc Stock (PYXS) Latest News

pulisher
Apr 12, 2026

PYXS | Pyxis Oncology, Inc. Common Insider Trading - Quiver Quantitative

Apr 12, 2026
pulisher
Apr 12, 2026

Growth Value: Will Pyxis Oncology Inc stock benefit from M ARate Cut & Weekly Stock Breakout Alerts - baoquankhu1.vn

Apr 12, 2026
pulisher
Apr 10, 2026

PYXS Stock Price, Quote & Chart | PYXIS ONCOLOGY INC (NASDAQ:PYXS) - ChartMill

Apr 10, 2026
pulisher
Apr 09, 2026

Stock Recap: Can Pyxis Oncology Inc benefit from deglobalization2026 Earnings & Verified Chart Pattern Signals - baoquankhu1.vn

Apr 09, 2026
pulisher
Apr 09, 2026

Price Action: Is Pyxis Oncology Inc part of any major index2026 Reactions & Low Drawdown Momentum Ideas - baoquankhu1.vn

Apr 09, 2026
pulisher
Apr 06, 2026

Trade Report: Can Pyxis Oncology Inc expand its profit marginsCPI Data & Safe Entry Momentum Stock Tips - baoquankhu1.vn

Apr 06, 2026
pulisher
Apr 05, 2026

Wall Street Zen Downgrades Pyxis Oncology (NASDAQ:PYXS) to Sell - marketbeat.com

Apr 05, 2026
pulisher
Apr 04, 2026

PYXS Technical Analysis & Stock Price Forecast - Intellectia AI

Apr 04, 2026
pulisher
Apr 04, 2026

PYXS SEC FilingsPyxis Oncology, Inc. 10-K, 10-Q, 8-K Forms - Stock Titan

Apr 04, 2026
pulisher
Mar 31, 2026

PYXS Earnings History & Surprises | EPS & Revenue Results | PYXIS ONCOLOGY INC (NASDAQ:PYXS) - ChartMill

Mar 31, 2026
pulisher
Mar 30, 2026

Pyxis Oncology Inc. (PYXS) Stock Price | Live Quotes & Charts | NASDAQ - StocksToTrade

Mar 30, 2026
pulisher
Mar 29, 2026

Pyxis Oncology (PYXS) Receives a Rating Update from a Top Analyst - The Globe and Mail

Mar 29, 2026
pulisher
Mar 28, 2026

Pyxis Oncology (NASDAQ:PYXS) Stock Rating Upgraded by Wall Street Zen - marketbeat.com

Mar 28, 2026
pulisher
Mar 27, 2026

HC Wainwright Raises Earnings Estimates for Pyxis Oncology - Defense World

Mar 27, 2026
pulisher
Mar 26, 2026

Stock Report: Can Pyxis Oncology Inc expand its profit marginsDividend Hike & Advanced Swing Trade Entry Alerts - baoquankhu1.vn

Mar 26, 2026
pulisher
Mar 26, 2026

Q1 EPS Estimates for Pyxis Oncology Raised by HC Wainwright - MarketBeat

Mar 26, 2026
pulisher
Mar 26, 2026

HC Wainwright Expects Increased Earnings for Pyxis Oncology - Defense World

Mar 26, 2026
pulisher
Mar 25, 2026

Pyxis Oncology director Humphrey sells $15917 in shares By Investing.com - Investing.com Australia

Mar 25, 2026
pulisher
Mar 25, 2026

Pyxis Oncology (PYXS) director receives 45,867 stock options at $1.36 strike - Stock Titan

Mar 25, 2026
pulisher
Mar 25, 2026

Pyxis Oncology director Humphrey sells $15917 in shares - Investing.com UK

Mar 25, 2026
pulisher
Mar 25, 2026

Pyxis Oncology (PYXS) grants director Jakob Dupont 45,867 stock options - stocktitan.net

Mar 25, 2026
pulisher
Mar 25, 2026

Executive at Pyxis Oncology (PYXS) receives new option and RSU equity grants - stocktitan.net

Mar 25, 2026
pulisher
Mar 25, 2026

Pyxis Oncology (PYXS) director receives grant of 45,867 stock options - Stock Titan

Mar 25, 2026
pulisher
Mar 25, 2026

[Form 4] Pyxis Oncology, Inc. Insider Trading Activity - Stock Titan

Mar 25, 2026
pulisher
Mar 25, 2026

Director at Pyxis Oncology (PYXS) receives grant of 45,867 stock options - Stock Titan

Mar 25, 2026
pulisher
Mar 25, 2026

Pyxis Oncology (NASDAQ:PYXS) Director Rachel Humphrey Sells 13,896 Shares - MarketBeat

Mar 25, 2026
pulisher
Mar 25, 2026

Pyxis Oncology (PYXS) director sells 15,496 shares under 10b5-1 plan - Stock Titan

Mar 25, 2026
pulisher
Mar 25, 2026

FY2029 EPS Estimates for Pyxis Oncology Lifted by Analyst - MarketBeat

Mar 25, 2026
pulisher
Mar 24, 2026

LifeSci Capital Maintains Pyxis Oncology(PYXS.US) With Buy Rating, Maintains Target Price $5 - Moomoo

Mar 24, 2026
pulisher
Mar 24, 2026

A Quick Look at Today's Ratings for Pyxis Oncology(PYXS.US), With a Forecast Between $5 to $7 - Moomoo

Mar 24, 2026
pulisher
Mar 24, 2026

Stifel Nicolaus Lowers Pyxis Oncology (NASDAQ:PYXS) Price Target to $8.00 - marketbeat.com

Mar 24, 2026
pulisher
Mar 24, 2026

Stifel cuts Pyxis Oncology stock price target on financing assumptions By Investing.com - Investing.com India

Mar 24, 2026
pulisher
Mar 24, 2026

Pyxis Oncology (NASDAQ:PYXS) Given Buy Rating at HC Wainwright - MarketBeat

Mar 24, 2026
pulisher
Mar 24, 2026

Guggenheim reiterates Buy on Pyxis Oncology stock ahead of trial data By Investing.com - Investing.com South Africa

Mar 24, 2026
pulisher
Mar 24, 2026

Guggenheim reiterates Buy on Pyxis Oncology stock ahead of trial data - Investing.com India

Mar 24, 2026
pulisher
Mar 24, 2026

H.C. Wainwright reiterates Buy on Pyxis Oncology stock, $7 target By Investing.com - Investing.com India

Mar 24, 2026
pulisher
Mar 24, 2026

H.C. Wainwright reiterates Buy on Pyxis Oncology stock, $7 target - Investing.com

Mar 24, 2026
pulisher
Mar 24, 2026

Pyxis Oncology (PYXS) Rating Reiterated as Buy by HC Wainwright & Co. | PYXS Stock News - GuruFocus

Mar 24, 2026
pulisher
Mar 24, 2026

RBC Capital Initiates Pyxis Oncology(PYXS.US) With Buy Rating, Announces Target Price $5 - Moomoo

Mar 24, 2026
pulisher
Mar 24, 2026

Stifel cuts Pyxis Oncology stock price target on financing assumptions - Investing.com

Mar 24, 2026
pulisher
Mar 24, 2026

Pyxis Oncology Reports 2025 Financial Results, Advances MICVO Cancer Trials, and Announces New Leadership - Minichart

Mar 24, 2026
pulisher
Mar 23, 2026

Pyxis Oncology Reports Q4 Results, Advances MICVO Program - TipRanks

Mar 23, 2026
pulisher
Mar 23, 2026

William Blair reiterates Pyxis Oncology stock rating on trial pace By Investing.com - Investing.com Canada

Mar 23, 2026
pulisher
Mar 23, 2026

William Blair reiterates Pyxis Oncology stock rating on trial pace - Investing.com UK

Mar 23, 2026
pulisher
Mar 23, 2026

Jefferies raises Pyxis Oncology stock price target on drug data By Investing.com - Investing.com Australia

Mar 23, 2026
pulisher
Mar 23, 2026

Jefferies raises Pyxis Oncology stock price target on drug data - Investing.com

Mar 23, 2026
pulisher
Mar 23, 2026

MicuRx Pharmaceuticals: Advancing Novel ADC Therapy MICVO for Difficult-to-Treat Head and Neck Cancer – Pipeline, Strategy, and Risks Overview - Minichart

Mar 23, 2026
pulisher
Mar 23, 2026

Pyxis Oncology, Inc. Reports Earnings Results for the Full Year Ended December 31, 2025 - marketscreener.com

Mar 23, 2026
pulisher
Mar 23, 2026

Pyxis Oncology (NASDAQ:PYXS) Posts Earnings Results, Beats Expectations By $0.06 EPS - MarketBeat

Mar 23, 2026

Pyxis Oncology Inc Stock (PYXS) Financials Data

Revenue

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EPS

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Pyxis Oncology Inc Stock (PYXS) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
HUMPHREY RACHEL
Director
Apr 17 '25
Sale
0.97
200
194
95,205
$53.70
price up icon 2.76%
$48.55
price down icon 0.79%
$99.97
price up icon 1.30%
$149.98
price up icon 1.99%
$151.44
price down icon 1.65%
ONC ONC
$313.74
price up icon 1.40%
Cap:     |  Volume (24h):