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Agios Pharmaceuticals Inc stock is traded at $34.16, with a volume of 2.24M. It is up +3.26% in the last 24 hours and up +21.09% over the past month. Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.
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Previous Close:
$33.08
Open:
$33.9
24h Volume:
2.24M
Relative Volume:
2.01
Market Cap:
$2.03B
Revenue:
$66.05M
Net Income/Loss:
$-422.60M
P/E Ratio:
-4.7111
EPS:
-7.251
Net Cash Flow:
$-384.73M
1W Performance:
+18.94%
1M Performance:
+21.09%
6M Performance:
+38.13%
1Y Performance:
-3.77%
1-Day Range:
Value
$33.50
$34.45
1-Week Range:
Value
$28.51
$34.45
52-Week Range:
Value
$22.24
$46.00

Agios Pharmaceuticals Inc Stock (AGIO) Company Profile

Name
Name
Agios Pharmaceuticals Inc
Name
Phone
617-649-8600
Name
Address
88 SIDNEY STREET, CAMBRIDGE, MA
Name
Employee
540
Name
Twitter
@AgiosPharma
Name
Next Earnings Date
2026-07-30
Name
Latest SEC Filings
Name
AGIO's Discussions on Twitter

Compare AGIO vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
AGIO icon
AGIO
Agios Pharmaceuticals Inc
34.16 2.03B 66.05M -422.60M -384.73M -7.251
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
451.63 114.63B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
609.94 63.95B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
877.72 54.58B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
278.09 37.13B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
162.99 34.65B 742.00K -1.37B -1.07B -7.0731

Agios Pharmaceuticals Inc Stock (AGIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-20-26 Reiterated H.C. Wainwright Buy
Nov-24-25 Initiated Truist Buy
Nov-20-25 Upgrade Leerink Partners Market Perform → Outperform
Nov-19-25 Downgrade RBC Capital Mkts Outperform → Sector Perform
Feb-24-25 Initiated H.C. Wainwright Buy
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-10-24 Resumed Raymond James Outperform
Sep-27-24 Downgrade Leerink Partners Outperform → Market Perform
Feb-08-24 Initiated Cantor Fitzgerald Overweight
Feb-03-23 Initiated Piper Sandler Overweight
Nov-17-22 Upgrade Goldman Sell → Neutral
Jul-27-22 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-03-21 Initiated BofA Securities Buy
Jul-30-21 Downgrade Goldman Neutral → Sell
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-10-21 Initiated H.C. Wainwright Buy
Mar-01-21 Downgrade JP Morgan Overweight → Neutral
Mar-01-21 Upgrade SVB Leerink Mkt Perform → Outperform
Feb-26-21 Downgrade SVB Leerink Outperform → Mkt Perform
Oct-22-20 Upgrade Barclays Equal Weight → Overweight
Mar-04-20 Initiated Barclays Equal Weight
Nov-26-19 Initiated Cantor Fitzgerald Overweight
Sep-23-19 Upgrade Guggenheim Neutral → Buy
May-23-19 Resumed Goldman Neutral
Feb-15-19 Upgrade SVB Leerink Mkt Perform → Outperform
Sep-25-18 Initiated Leerink Partners Mkt Perform
May-23-18 Initiated Citigroup Buy
Apr-11-18 Reiterated Credit Suisse Outperform
Feb-15-18 Reiterated Needham Buy
Feb-15-18 Reiterated SunTrust Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-10-17 Reiterated Needham Buy
Aug-08-17 Reiterated SunTrust Buy
Aug-02-17 Upgrade Leerink Partners Mkt Perform → Outperform
Jun-26-17 Downgrade Janney Buy → Neutral
Jan-17-17 Upgrade Oppenheimer Perform → Outperform
Oct-24-16 Initiated Needham Buy
Jun-13-16 Upgrade JP Morgan Neutral → Overweight
May-18-16 Reiterated SunTrust Buy
View All

Agios Pharmaceuticals Inc Stock (AGIO) Latest News

pulisher
Jun 18, 2026

Agios Pharma Shareholders Expand Equity Plan, Reelect Directors - TipRanks

Jun 18, 2026
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Jun 18, 2026

Agios Pharmaceuticals (NASDAQ: AGIO) boosts 2023 stock plan by 2M shares - Stock Titan

Jun 18, 2026
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Jun 18, 2026

AGIO stock surges 35% in six months: What's driving it? - MSN

Jun 18, 2026
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Jun 18, 2026

Agios Targets Transfusion Burden in Sickle Cell Disease With New Phase 3 Bet on Mitapivat - TipRanks

Jun 18, 2026
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Jun 18, 2026

AGIO Stock Surges 35% in Six Months: What's Driving It? - The Globe and Mail

Jun 18, 2026
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Jun 17, 2026

Agios Pharmaceuticals Inc (AGIO) Institutional Confidence - TradingKey

Jun 17, 2026
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Jun 17, 2026

Agios Pharmaceuticals Inc (AGIO) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jun 17, 2026
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Jun 17, 2026

Agios Pharmaceuticals Inc (AGIO) Financial Health: Profitability & Balance Sheet Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Agios Pharmaceuticals Inc (AGIO) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jun 17, 2026
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Jun 17, 2026

Agios Pharmaceuticals Inc (AGIO) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jun 17, 2026
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Jun 17, 2026

Agios Pharmaceuticals Inc (AGIO) Valuation: PE, PB & Fair Value Analysis - TradingKey

Jun 17, 2026
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Jun 17, 2026

Agios Pharmaceuticals Inc (AGIO) Revenue Breakdown: Business Segments, Regional Revenue & Profit Contribution - TradingKey

Jun 17, 2026
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Jun 17, 2026

Agios Pharmaceuticals Inc (AGIO) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jun 17, 2026
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Jun 16, 2026

Agios Pharmaceuticals touts mitapivat gains despite sickle cell pain miss - MSN

Jun 16, 2026
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Jun 16, 2026

AGIOS (AGIO) director Catherine Owen Adams converts 1,976 RSUs into common stock - Stock Titan

Jun 16, 2026
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Jun 16, 2026

Agios (NASDAQ: AGIO) director converts 1,976 RSUs, holds 8,049 shares - Stock Titan

Jun 16, 2026
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Jun 16, 2026

Agios Pharmaceuticals (AGIO) Declines as Stock Hovers Between Key Support and Resistance LevelsDealer Positioning - newsline.com

Jun 16, 2026
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Jun 15, 2026

Agios Pharmaceuticals, Inc. (AGIO) Discusses New Data and Strategic Expansion in Rare Hematology at EHA Investor EventSlideshow (NASDAQ:AGIO) 2026-06-15 - Seeking Alpha

Jun 15, 2026
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Jun 15, 2026

Agios Pharmaceuticals (AGIO) Is Up 7.4% After Mitapivat RISE UP Data in Sickle Cell DiseaseHas The Bull Case Changed? - Sahm

Jun 15, 2026
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Jun 15, 2026

Agios to discontinue candidate for myelodysplastic syndromes - MSN

Jun 15, 2026
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Jun 14, 2026

Agios Pharmaceuticals (AGIO) Reports Promising Results from Phas - GuruFocus

Jun 14, 2026
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Jun 13, 2026

Agios Pharmaceuticals Touts Mitapivat Gains Despite Sickle Cell Pain Miss - Yahoo Finance

Jun 13, 2026
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Jun 13, 2026

AGIO: Mitapivat shows durable efficacy in rare hematology, supporting growth and pipeline expansion - TradingView

Jun 13, 2026
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Jun 13, 2026

Technical Reactions to AGIO Trends in Macro Strategies - Stock Traders Daily

Jun 13, 2026
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Jun 13, 2026

Agios presents detailed mitapivat trial results for sickle cell - Investing.com UK

Jun 13, 2026
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Jun 13, 2026

Agios presents detailed mitapivat trial results for sickle cell By Investing.com - Investing.com Australia

Jun 13, 2026
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Jun 13, 2026

Agios Showcases RISE UP Phase 3 Results at EHA 2026 Plenary Session Reinforcing Strong Anti-Hemolytic Profile of Mitapivat in Sickle Cell Disease - The Manila Times

Jun 13, 2026
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Jun 13, 2026

Agios Pharmaceuticals Reports Positive Phase 3 Results for Mitapivat in Sickle Cell Disease, Highlighting Hemoglobin Response and Reduced Transfusion Burden - Quiver Quantitative

Jun 13, 2026
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Jun 13, 2026

Agios Showcases RISE UP Phase 3 Results at EHA 2026 Plenary Session Reinforcing Strong ... - Caledonian Record

Jun 13, 2026
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Jun 13, 2026

Sickle cell patients needed fewer transfusions with Agios pill in Phase 3 - Stock Titan

Jun 13, 2026
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Jun 11, 2026

Agios Pharmaceuticals (NASDAQ:AGIO) Given New $31.00 Price Target at JPMorgan Chase & Co. - MarketBeat

Jun 11, 2026
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Jun 11, 2026

J.P. Morgan Maintains Agios Pharmaceuticals(AGIO.US) With Hold Rating, Maintains Target Price $31 - Moomoo

Jun 11, 2026
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Jun 11, 2026

GW&K Investment Management LLC Purchases 354,359 Shares of Agios Pharmaceuticals, Inc. $AGIO - MarketBeat

Jun 11, 2026
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Jun 10, 2026

J.P. Morgan Maintains Agios Pharmaceuticals(AGIO.US) With Hold Rating, Announces Target Price $31 - Moomoo

Jun 10, 2026
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Jun 10, 2026

Capital International Investors Buys New Position in Agios Pharmaceuticals, Inc. $AGIO - MarketBeat

Jun 10, 2026
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Jun 10, 2026

Agios Pharmaceuticals, Inc. $AGIO Shares Bought by BNP Paribas Financial Markets - MarketBeat

Jun 10, 2026
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Jun 09, 2026

‘Disciplined’ $665M deal moves Oscotec’s cevidoplenib to Agios - BioWorld News

Jun 09, 2026
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Jun 09, 2026

Eyes on Asia: Olix, Agios, Eli Lilly - BioXconomy

Jun 09, 2026
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Jun 09, 2026

Analysts’ Top Healthcare Picks: McKesson (MCK), Agios Pharma (AGIO) - The Globe and Mail

Jun 09, 2026
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Jun 09, 2026

BofA Securities Maintains Agios Pharmaceuticals(AGIO.US) With Buy Rating, Maintains Target Price $40 - Moomoo

Jun 09, 2026
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Jun 08, 2026

Alpha Thalassemia Market Emerging as a High-Growth Healthcare Investment Space Through 2036 – DelveInsight | Forma Therapeutics, Genmedicn Biopharma, Bristol-Myers Squibb, Agios Pharma - Barchart.com

Jun 08, 2026
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Jun 08, 2026

Erste Asset Management GmbH Acquires 40,000 Shares of Agios Pharmaceuticals, Inc. $AGIO - MarketBeat

Jun 08, 2026
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Jun 07, 2026

The week in pharma: action, reaction and insight – week to June 5, 2026 - The Pharma Letter

Jun 07, 2026
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Jun 06, 2026

Why Agios Pharmaceuticals (AGIO) Is Down 5.4% After Overhauling Its Hematology PortfolioAnd What's Next - Sahm

Jun 06, 2026
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Jun 06, 2026

Agios Pharmaceuticals | 144: Notice of proposed sale of securities pursuant to Rule 144 - Moomoo

Jun 06, 2026
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Jun 04, 2026

Q2 EPS Estimate for Agios Pharmaceuticals Reduced by Analyst - MarketBeat

Jun 04, 2026
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Jun 04, 2026

A Look At Agios Pharmaceuticals (AGIO) Valuation After The Cevidoplenib Licensing Agreement - Sahm

Jun 04, 2026
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Jun 03, 2026

AGIO secures global rights to late-stage rare blood disorder candidate - MSN

Jun 03, 2026
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Jun 03, 2026

How The Tebapivat Setback Is Reframing The Story For Agios Pharmaceuticals (AGIO) - Yahoo Finance

Jun 03, 2026
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Jun 02, 2026

AGIO Secures Global Rights to Late-Stage Rare Blood Disorder Candidate - The Globe and Mail

Jun 02, 2026
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Jun 02, 2026

Trading the Move, Not the Narrative: (AGIO) Edition - Stock Traders Daily

Jun 02, 2026

Agios Pharmaceuticals Inc Stock (AGIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Agios Pharmaceuticals Inc Stock (AGIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
CAPELLO JEFFREY D
Director
Jun 13 '26
Option Exercise
0.00
1,976
0
8,049
Burns James William
Chief Legal Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
52,586
Burns James William
Chief Legal Officer
Apr 02 '26
Sale
34.71
3,280
113,849
49,306
Gheuens Sarah
Chief Medical Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
83,217
Gheuens Sarah
Chief Medical Officer
Apr 02 '26
Sale
34.71
2,940
102,047
80,277
Jones Cecilia
Chief Financial Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
58,139
Jones Cecilia
Chief Financial Officer
Apr 02 '26
Sale
34.71
3,141
109,024
54,998
Milanova Tsveta
Chief Commercial Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
50,091
Milanova Tsveta
Chief Commercial Officer
Apr 02 '26
Sale
34.71
3,262
113,224
46,829
Viswanadhan Krishnan
Chief Corp Dev & Strategy
Apr 02 '26
Option Exercise
0.00
8,100
0
13,241
$31.43
price up icon 0.74%
$90.89
price down icon 1.44%
$52.96
price down icon 1.38%
$63.96
price up icon 3.50%
ONC ONC
$270.15
price up icon 2.84%
$162.99
price up icon 3.31%
Cap:     |  Volume (24h):