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Agios Pharmaceuticals Inc stock is traded at $35.01, with a volume of 1.16M. It is down -2.72% in the last 24 hours and down -7.97% over the past month. Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.
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Previous Close:
$35.99
Open:
$35.83
24h Volume:
1.16M
Relative Volume:
1.09
Market Cap:
$2.08B
Revenue:
$66.05M
Net Income/Loss:
$-422.60M
P/E Ratio:
-4.8283
EPS:
-7.251
Net Cash Flow:
$-384.73M
1W Performance:
-2.88%
1M Performance:
-7.97%
6M Performance:
+26.80%
1Y Performance:
-7.21%
1-Day Range:
Value
$34.87
$36.37
1-Week Range:
Value
$34.87
$38.74
52-Week Range:
Value
$22.24
$46.00

Agios Pharmaceuticals Inc Stock (AGIO) Company Profile

Name
Name
Agios Pharmaceuticals Inc
Name
Phone
617-649-8600
Name
Address
88 SIDNEY STREET, CAMBRIDGE, MA
Name
Employee
540
Name
Twitter
@AgiosPharma
Name
Next Earnings Date
2026-07-30
Name
Latest SEC Filings
Name
AGIO's Discussions on Twitter

Compare AGIO vs VRTX, REGN, ARGX, RVMD, ALNY

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
AGIO icon
AGIO
Agios Pharmaceuticals Inc
35.01 2.20B 66.05M -422.60M -384.73M -7.251
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
483.33 121.57B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
695.42 69.95B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
882.56 55.61B 4.16B 1.29B 734.26M 19.58
RVMD icon
RVMD
Revolution Medicines Inc
180.92 39.98B 742.00K -1.37B -1.07B -7.0731
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
286.62 37.17B 4.29B 577.22M 641.34M 4.2086

Agios Pharmaceuticals Inc Stock (AGIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-20-26 Reiterated H.C. Wainwright Buy
Nov-24-25 Initiated Truist Buy
Nov-20-25 Upgrade Leerink Partners Market Perform → Outperform
Nov-19-25 Downgrade RBC Capital Mkts Outperform → Sector Perform
Feb-24-25 Initiated H.C. Wainwright Buy
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-10-24 Resumed Raymond James Outperform
Sep-27-24 Downgrade Leerink Partners Outperform → Market Perform
Feb-08-24 Initiated Cantor Fitzgerald Overweight
Feb-03-23 Initiated Piper Sandler Overweight
Nov-17-22 Upgrade Goldman Sell → Neutral
Jul-27-22 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-03-21 Initiated BofA Securities Buy
Jul-30-21 Downgrade Goldman Neutral → Sell
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-10-21 Initiated H.C. Wainwright Buy
Mar-01-21 Downgrade JP Morgan Overweight → Neutral
Mar-01-21 Upgrade SVB Leerink Mkt Perform → Outperform
Feb-26-21 Downgrade SVB Leerink Outperform → Mkt Perform
Oct-22-20 Upgrade Barclays Equal Weight → Overweight
Mar-04-20 Initiated Barclays Equal Weight
Nov-26-19 Initiated Cantor Fitzgerald Overweight
Sep-23-19 Upgrade Guggenheim Neutral → Buy
May-23-19 Resumed Goldman Neutral
Feb-15-19 Upgrade SVB Leerink Mkt Perform → Outperform
Sep-25-18 Initiated Leerink Partners Mkt Perform
May-23-18 Initiated Citigroup Buy
Apr-11-18 Reiterated Credit Suisse Outperform
Feb-15-18 Reiterated Needham Buy
Feb-15-18 Reiterated SunTrust Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-10-17 Reiterated Needham Buy
Aug-08-17 Reiterated SunTrust Buy
Aug-02-17 Upgrade Leerink Partners Mkt Perform → Outperform
Jun-26-17 Downgrade Janney Buy → Neutral
Jan-17-17 Upgrade Oppenheimer Perform → Outperform
Oct-24-16 Initiated Needham Buy
Jun-13-16 Upgrade JP Morgan Neutral → Overweight
May-18-16 Reiterated SunTrust Buy
View All

Agios Pharmaceuticals Inc Stock (AGIO) Latest News

pulisher
Jul 28, 2026

AGIO|Agios Pharmaceuticals Inc|Price:36.308|Chg%:-0.662 - TradingKey

Jul 28, 2026
pulisher
Jul 28, 2026

Understanding the Setup: (AGIO) and Scalable Risk - Stock Traders Daily

Jul 28, 2026
pulisher
Jul 28, 2026

The Zacks Analyst Blog Highlights Harmony Biosciences, Acadia Pharmaceuticals, Biogen, Insmed and Agios Pharmaceuticals - Yahoo Finance

Jul 28, 2026
pulisher
Jul 27, 2026

Agios Pharmaceuticals Inc (AGIO) Dividends & Stock Splits: Historical Payouts and Event Timeline - TradingKey

Jul 27, 2026
pulisher
Jul 27, 2026

Agios Pharmaceuticals Inc (AGIO) Cash Flow - TradingKey

Jul 27, 2026
pulisher
Jul 27, 2026

Agios Pharmaceuticals Inc (AGIO) Revenue Breakdown: Business Segments, Regional Revenue & Profit Contribution - TradingKey

Jul 27, 2026
pulisher
Jul 26, 2026

Agios Pharmaceuticals Inc (AGIO) Technical Analysis: Support, Resistance, Indicators & Moving Averages - TradingKey

Jul 26, 2026
pulisher
Jul 26, 2026

Agios Pharmaceuticals Inc (AGIO) Earnings Forecast: Future EPS & Revenue Growth Estimates - TradingKey

Jul 26, 2026
pulisher
Jul 26, 2026

Agios Pharmaceuticals Inc (AGIO) Shareholder Structure: Major Shareholders & Institutional Holdings - TradingKey

Jul 26, 2026
pulisher
Jul 25, 2026

Agios Pharmaceuticals, Inc. Revenue Breakdown – NASDAQ:AGIO - TradingView

Jul 25, 2026
pulisher
Jul 24, 2026

Agios Pharmaceuticals Inc. (AGIO) Stock Price | Live Quotes & Charts | NASDAQ - timothysykes.com

Jul 24, 2026
pulisher
Jul 24, 2026

Agios Pharmaceuticals Inc (AGIO) Risk Assessment: Volatility, Financial Risk & Investment Risk - TradingKey

Jul 24, 2026
pulisher
Jul 24, 2026

Analysts Offer Insights on Healthcare Companies: Agios Pharma (AGIO) and Imunon (IMNN) - The Globe and Mail

Jul 24, 2026
pulisher
Jul 23, 2026

Agios Pharmaceuticals (AGIO) Expected to Beat Earnings Estimates: What to Know Ahead of Q2 Release - Yahoo Finance

Jul 23, 2026
pulisher
Jul 22, 2026

Agios Reports Neutral Sickle Cell Data, Decides To Stop Development - Sahm

Jul 22, 2026
pulisher
Jul 22, 2026

AGIO Shares Sink Nearly 7% After Scrapping the Tebapivat SCD Program - Yahoo Finance

Jul 22, 2026
pulisher
Jul 22, 2026

H.C. Wainwright lowers Agios Pharma price target to $52 on trial data By Investing.com - Investing.com South Africa

Jul 22, 2026
pulisher
Jul 22, 2026

H.C. Wainwright lowers Agios Pharma price target to $52 on trial data - Investing.com

Jul 22, 2026
pulisher
Jul 22, 2026

Agios Pharmaceuticals (AGIO) Sees 13% Drop Following Trial Resul - GuruFocus

Jul 22, 2026
pulisher
Jul 22, 2026

Agios Pharmaceuticals Reports Phase 2 Trial Results for Tebapiva - GuruFocus

Jul 22, 2026
pulisher
Jul 22, 2026

Agios Pharmaceuticals (AGIO) Ends Development of Sickle Cell Dru - GuruFocus

Jul 22, 2026
pulisher
Jul 21, 2026

AGIO Maintained by HC Wainwright & Co. -- Price Target Lowered t - GuruFocus

Jul 21, 2026
pulisher
Jul 21, 2026

Agios scraps sickle cell treatment after trial shows limited benefit - Reuters

Jul 21, 2026
pulisher
Jul 21, 2026

Agios Pharmaceuticals stock falls on trial update - Investing.com

Jul 21, 2026
pulisher
Jul 21, 2026

Agios Pharma Drops Sickle Cell Disease Drug After Phase 2 Data Disappoint - MedCity News

Jul 21, 2026
pulisher
Jul 21, 2026

Agios pares loss after abandoning sickle cell asset tebapivat (AGIO:NASDAQ) - Seeking Alpha

Jul 21, 2026
pulisher
Jul 21, 2026

Agios scraps sickle cell drug - BioPharma Dive

Jul 21, 2026
pulisher
Jul 21, 2026

Why Agios Pharma, A Novo Rival, Just Pulled A Bearish Move - Investor's Business Daily

Jul 21, 2026
pulisher
Jul 21, 2026

Trial miss for Agios Pharma’s tebapivat in sickle cell disease - The Pharma Letter

Jul 21, 2026
pulisher
Jul 21, 2026

Agios scraps sickle cell drug programme on underwhelming Phase II data - Yahoo Finance

Jul 21, 2026
pulisher
Jul 21, 2026

Agios axes next-gen sickle cell candidate after it fails to best Novo’s asset - BioSpace

Jul 21, 2026
pulisher
Jul 21, 2026

Agios Shelves Tebapivat In Sickle Cell, Weeks After MDS Exit - insights.citeline.com

Jul 21, 2026
pulisher
Jul 21, 2026

Why Is AGIO Stock Falling Today? - TradingView

Jul 21, 2026
pulisher
Jul 21, 2026

Agios shares tumble after discontinuing sickle cell disease programme following Phase 2 trial (AGIO) - Yahoo Finance

Jul 21, 2026
pulisher
Jul 21, 2026

Agios halts tebapivat development in sickle cell disease - Investing.com

Jul 21, 2026
pulisher
Jul 21, 2026

Agios halts tebapivat development in sickle cell disease By Investing.com - Investing.com Nigeria

Jul 21, 2026
pulisher
Jul 21, 2026

Agios Pharmaceuticals stock falls on trial update By Investing.com - Investing.com Canada

Jul 21, 2026
pulisher
Jul 21, 2026

Agios Pharmaceuticals Reports Phase 2 Tebapivat Sickle Cell Disease Results, Discontinues Development of the Candidate - Quiver Quantitative

Jul 21, 2026
pulisher
Jul 21, 2026

Agios Pharmaceuticals Shares Down 12.6% Prema - Moomoo

Jul 21, 2026
pulisher
Jul 21, 2026

Agios Provides Update on Phase 2 Trial of Tebapivat in Sickle Cell Disease - The Manila Times

Jul 21, 2026
pulisher
Jul 21, 2026

Tebapivat 5 mg Arm: 47.1% Hemoglobin Response; Agios Won’t Advance - Stock Titan

Jul 21, 2026
pulisher
Jul 19, 2026

The Bull Case For Agios Pharmaceuticals (AGIO) Could Change Following FDA Priority Review For Mitapivat In Sickle Cell - simplywall.st

Jul 19, 2026
pulisher
Jul 18, 2026

Agios gains FDA priority review for Pyrukynd label expansion - MSN

Jul 18, 2026
pulisher
Jul 16, 2026

The Technical Signals Behind (AGIO) That Institutions Follow - Stock Traders Daily

Jul 16, 2026
pulisher
Jul 16, 2026

Agios Pharmaceuticals (AGIO) Wins Priority Review, Is The Stock Now Fully Valued? - Sahm

Jul 16, 2026
pulisher
Jul 15, 2026

Avanzanite Bioscience’s Partner Agios Announces PYRUKYND® (mitapivat) Approval in the European Union for Adults with Thalassaemia - AOL.com

Jul 15, 2026
pulisher
Jul 14, 2026

H.C. Wainwright Maintains Agios Pharmaceuticals(AGIO.US) With Buy Rating, Maintains Target Price $54 - Moomoo

Jul 14, 2026
pulisher
Jul 13, 2026

AGIO 260717 45.00P (AGIO260717P45000) Latest Announcements - Moomoo

Jul 13, 2026
pulisher
Jul 10, 2026

Agios Pharmaceuticals (NASDAQ: AGIO) director reports 1,447-share equity award and 2,894 RSUs - Stock Titan

Jul 10, 2026
pulisher
Jul 10, 2026

Here's Why Shares in Novo Nordisk Rival, Agios Pharmaceutical, Soared This Week - AOL.com

Jul 10, 2026
pulisher
Jul 09, 2026

Is Agios Pharmaceuticals (AGIO) A Bargain After FDA Priority Review For Mitapivat? - Yahoo Finance

Jul 09, 2026

Agios Pharmaceuticals Inc Stock (AGIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Agios Pharmaceuticals Inc Stock (AGIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Gheuens Sarah
Chief Medical Officer
Jul 01 '26
Sale
37.56
4,007
150,503
84,645
$92.95
price up icon 0.54%
$32.87
price down icon 2.87%
$127.10
price down icon 2.18%
$59.18
price down icon 1.32%
ONC ONC
$327.21
price down icon 0.98%
$286.62
price down icon 0.62%
Cap:     |  Volume (24h):