41.23
price down icon3.65%   -1.56
after-market After Hours: 41.23
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Agios Pharmaceuticals Inc stock is traded at $41.23, with a volume of 1.11M. It is down -3.65% in the last 24 hours and up +42.76% over the past month. Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.
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Previous Close:
$42.79
Open:
$42.93
24h Volume:
1.11M
Relative Volume:
0.98
Market Cap:
$2.45B
Revenue:
$66.05M
Net Income/Loss:
$-422.60M
P/E Ratio:
-5.6861
EPS:
-7.251
Net Cash Flow:
$-384.73M
1W Performance:
+9.71%
1M Performance:
+42.76%
6M Performance:
+45.12%
1Y Performance:
+4.30%
1-Day Range:
Value
$40.26
$42.93
1-Week Range:
Value
$36.77
$44.09
52-Week Range:
Value
$22.24
$46.00

Agios Pharmaceuticals Inc Stock (AGIO) Company Profile

Name
Name
Agios Pharmaceuticals Inc
Name
Phone
617-649-8600
Name
Address
88 SIDNEY STREET, CAMBRIDGE, MA
Name
Employee
540
Name
Twitter
@AgiosPharma
Name
Next Earnings Date
2026-07-30
Name
Latest SEC Filings
Name
AGIO's Discussions on Twitter

Compare AGIO vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
AGIO icon
AGIO
Agios Pharmaceuticals Inc
41.23 2.45B 66.05M -422.60M -384.73M -7.251
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
485.39 123.19B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
664.52 69.67B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
877.62 54.58B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
298.76 39.89B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
186.88 39.73B 742.00K -1.37B -1.07B -7.0731

Agios Pharmaceuticals Inc Stock (AGIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-20-26 Reiterated H.C. Wainwright Buy
Nov-24-25 Initiated Truist Buy
Nov-20-25 Upgrade Leerink Partners Market Perform → Outperform
Nov-19-25 Downgrade RBC Capital Mkts Outperform → Sector Perform
Feb-24-25 Initiated H.C. Wainwright Buy
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-10-24 Resumed Raymond James Outperform
Sep-27-24 Downgrade Leerink Partners Outperform → Market Perform
Feb-08-24 Initiated Cantor Fitzgerald Overweight
Feb-03-23 Initiated Piper Sandler Overweight
Nov-17-22 Upgrade Goldman Sell → Neutral
Jul-27-22 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-03-21 Initiated BofA Securities Buy
Jul-30-21 Downgrade Goldman Neutral → Sell
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-10-21 Initiated H.C. Wainwright Buy
Mar-01-21 Downgrade JP Morgan Overweight → Neutral
Mar-01-21 Upgrade SVB Leerink Mkt Perform → Outperform
Feb-26-21 Downgrade SVB Leerink Outperform → Mkt Perform
Oct-22-20 Upgrade Barclays Equal Weight → Overweight
Mar-04-20 Initiated Barclays Equal Weight
Nov-26-19 Initiated Cantor Fitzgerald Overweight
Sep-23-19 Upgrade Guggenheim Neutral → Buy
May-23-19 Resumed Goldman Neutral
Feb-15-19 Upgrade SVB Leerink Mkt Perform → Outperform
Sep-25-18 Initiated Leerink Partners Mkt Perform
May-23-18 Initiated Citigroup Buy
Apr-11-18 Reiterated Credit Suisse Outperform
Feb-15-18 Reiterated Needham Buy
Feb-15-18 Reiterated SunTrust Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-10-17 Reiterated Needham Buy
Aug-08-17 Reiterated SunTrust Buy
Aug-02-17 Upgrade Leerink Partners Mkt Perform → Outperform
Jun-26-17 Downgrade Janney Buy → Neutral
Jan-17-17 Upgrade Oppenheimer Perform → Outperform
Oct-24-16 Initiated Needham Buy
Jun-13-16 Upgrade JP Morgan Neutral → Overweight
May-18-16 Reiterated SunTrust Buy
View All

Agios Pharmaceuticals Inc Stock (AGIO) Latest News

pulisher
Jul 10, 2026

Agios Pharmaceuticals (NASDAQ: AGIO) director reports 1,447-share equity award and 2,894 RSUs - Stock Titan

Jul 10, 2026
pulisher
Jul 10, 2026

Avanzanite Bioscience’s Partner Agios Announces PYRUKYND® (mitapivat) Approval in the European Union for Adults with Thalassaemia - AOL.com

Jul 10, 2026
pulisher
Jul 10, 2026

Here's Why Shares in Novo Nordisk Rival, Agios Pharmaceutical, Soared This Week - AOL.com

Jul 10, 2026
pulisher
Jul 09, 2026

Is Agios Pharmaceuticals (AGIO) A Bargain After FDA Priority Review For Mitapivat? - Yahoo Finance

Jul 09, 2026
pulisher
Jul 09, 2026

Agios Pharmaceuticals (AGIO) Is Up 13.8% After FDA Grants Priority Review To Mitapivat In Sickle Cell Disease - Yahoo Finance

Jul 09, 2026
pulisher
Jul 08, 2026

Agios gains FDA priority review for Pyrukynd label expansion - MSN

Jul 08, 2026
pulisher
Jul 08, 2026

AGIO's Filing for Mitapivat in SCD Gets FDA's Priority Tag, Stock Up - The Globe and Mail

Jul 08, 2026
pulisher
Jul 08, 2026

Strength Seen in Agios Pharmaceuticals (AGIO): Can Its 17.7% Jump Turn into More Strength? - Yahoo Finance

Jul 08, 2026
pulisher
Jul 08, 2026

A Quick Look at Today's Ratings for Agios Pharmaceuticals(AGIO.US), With a Forecast Between $41 to $54 - Moomoo

Jul 08, 2026
pulisher
Jul 08, 2026

Eli Lilly Stock Forecast: Why Foundayo Access Could Push LLY Past $1,000 by Late 2026 - finance.biggo.com

Jul 08, 2026
pulisher
Jul 08, 2026

What Is Driving Focus on Agios Pharmaceuticals (NASDAQ:AGIO)? - Kalkine Media

Jul 08, 2026
pulisher
Jul 07, 2026

Truist Financial Maintains Agios Pharmaceuticals(AGIO.US) With Buy Rating, Raises Target Price to $41 - Moomoo

Jul 07, 2026
pulisher
Jul 07, 2026

AGIO Stock Jumps As Mitapivat Trial Data Fuels Bullish Targets - timothysykes.com

Jul 07, 2026
pulisher
Jul 07, 2026

After receiving priority review designation from the FDA for its sickle cell disease treatment, Agios Pharmaceuticals, Inc. shares surged by 12.4%. - Bitget

Jul 07, 2026
pulisher
Jul 07, 2026

Agios Pharmaceuticals (NASDAQ:AGIO) pops as FDA review moves price above average target - TechStock²

Jul 07, 2026
pulisher
Jul 07, 2026

Why Is Agios Pharma Stock Soaring Tuesday? - Benzinga

Jul 07, 2026
pulisher
Jul 07, 2026

H.C. Wainwright Maintains Agios Pharmaceuticals(AGIO.US) With Buy Rating, Maintains Target Price $54 - Moomoo

Jul 07, 2026
pulisher
Jul 07, 2026

Here's Why Agios Pharmaceuticals Stock Soared Today (Hint: It's FDA-Related) - The Motley Fool

Jul 07, 2026
pulisher
Jul 07, 2026

AGIO Maintained by RBC Capital -- Price Target Raised to $32 - GuruFocus

Jul 07, 2026
pulisher
Jul 07, 2026

Agios Pharmaceuticals (AGIO) Receives Priority Review from FDA f - GuruFocus

Jul 07, 2026
pulisher
Jul 07, 2026

Agios Pharmaceuticals (AGIO) Sees 13.5% Surge - GuruFocus

Jul 07, 2026
pulisher
Jul 07, 2026

AGIO Stock Jumps As Mitapivat Sickle Cell Data Fuels Hype - StocksToTrade

Jul 07, 2026
pulisher
Jul 07, 2026

Here's Why Agios Pharmaceuticals Stock Soared Today (Hint: It's FDA-Related) - The Motley Fool

Jul 07, 2026
pulisher
Jul 07, 2026

AGIO Stock Hits Over 7-Month Highs – FDA Catalyst, ‘Seasonally Strong’ Q2 Earnings Estimate Drive Optimism - Stocktwits

Jul 07, 2026
pulisher
Jul 07, 2026

Agios Pharmaceuticals (AGIO) Secures FDA Priority Review for Mit - GuruFocus

Jul 07, 2026
pulisher
Jul 07, 2026

Saol Therapeutics resubmits NDA for SL1009 - The Pharma Letter

Jul 07, 2026
pulisher
Jul 07, 2026

Agios Pharmaceuticals Shares Rise After FDA Grants Priority Review for Sickle Cell Treatment - marketscreener.com

Jul 07, 2026
pulisher
Jul 07, 2026

BofA Securities Adjusts Price Target on Agios Pharmaceuticals to $46 From $40, Maintains Buy Rating - Moomoo

Jul 07, 2026
pulisher
Jul 07, 2026

DigitalOcean, Agios Pharmaceuticals, Kingsoft Cloud And Other Big Stocks Moving Higher On Tuesday - Benzinga

Jul 07, 2026
pulisher
Jul 07, 2026

Agios Pharmaceuticals, Inc. Stock 12‑Month Price Target Raised to $42.62, Implies 14% Upside - TradingView

Jul 07, 2026
pulisher
Jul 07, 2026

FDA accepts Agios sNDA for mitapivat in sickle cell disease - Investing.com

Jul 07, 2026
pulisher
Jul 07, 2026

AGIO Maintained by B of A Securities -- Price Target Raised to $46 - GuruFocus

Jul 07, 2026
pulisher
Jul 07, 2026

Agios Pharmaceuticals (AGIO) Gains FDA Priority Review for Pyruk - GuruFocus

Jul 07, 2026
pulisher
Jul 07, 2026

Agios Says US FDA Grants Priority Review for Mitapivat to Treat Sickle Cell Disease - Moomoo

Jul 07, 2026
pulisher
Jul 07, 2026

Agios Pharmaceuticals (AGIO) Receives FDA Priority Review for Mi - GuruFocus

Jul 07, 2026
pulisher
Jul 07, 2026

RBC Capital Adjusts Agios Pharmaceuticals PT to $32 From $28, Maintains Sector Perform Rating - marketscreener.com

Jul 07, 2026
pulisher
Jul 07, 2026

FDA accepts Agios sNDA for mitapivat in sickle cell disease By Investing.com - Investing.com Canada

Jul 07, 2026
pulisher
Jul 07, 2026

FDA puts Agios' sickle cell drug on fast track to Nov. 1 review date - Stock Titan

Jul 07, 2026
pulisher
Jul 07, 2026

Pulling the plug on cancer: Agios Pharmaceuticals, Revolution Medicines, and Vidac Pharma - Stockhouse

Jul 07, 2026
pulisher
Jul 07, 2026

Price to sales forward of Agios Pharmaceuticals, Inc. – MUN:8AP - TradingView

Jul 07, 2026
pulisher
Jul 06, 2026

Price to sales forward of Agios Pharmaceuticals, Inc. – DUS:8AP - TradingView

Jul 06, 2026
pulisher
Jul 05, 2026

The Technical Signals Behind (AGIO) That Institutions Follow - Stock Traders Daily

Jul 05, 2026
pulisher
Jul 05, 2026

Price to book forward of Agios Pharmaceuticals, Inc. – NASDAQ:AGIO - TradingView

Jul 05, 2026
pulisher
Jul 03, 2026

AGIOAgios Pharmaceuticals Inc Latest SEC Filings - Finviz

Jul 03, 2026
pulisher
Jul 02, 2026

Agios Pharmaceuticals: CMO Sarah Gheuens sells $150,502 in stock By Investing.com - Investing.com Nigeria

Jul 02, 2026
pulisher
Jul 02, 2026

Agios Pharmaceuticals: CMO Sarah Gheuens sells $150,502 in stock - Investing.com

Jul 02, 2026
pulisher
Jul 02, 2026

D. E. Shaw reports 3.03M-share stake in Agios (AGIO) - Stock Titan

Jul 02, 2026
pulisher
Jul 02, 2026

Agios (NASDAQ: AGIO) CMO nets shares after RSU vesting and tax sale - Stock Titan

Jul 02, 2026
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Jul 02, 2026

Agios Pharmaceuticals | 4: Statement of changes in beneficial ownership of securities-Officer Gheuens Sarah - Moomoo

Jul 02, 2026
pulisher
Jul 01, 2026

AGIO (NASDAQ: AGIO) affiliate notifies plan to offer 4,007 shares via broker - Stock Titan

Jul 01, 2026
pulisher
Jul 01, 2026

Agios Pharmaceuticals | 144: Notice of proposed sale of securities pursuant to Rule 144 - Moomoo

Jul 01, 2026

Agios Pharmaceuticals Inc Stock (AGIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Agios Pharmaceuticals Inc Stock (AGIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Gheuens Sarah
Chief Medical Officer
Jul 01 '26
Sale
37.56
4,007
150,503
84,645
$56.43
price down icon 2.64%
$115.61
price down icon 2.24%
$35.97
price down icon 2.28%
$68.27
price down icon 10.83%
ONC ONC
$298.70
price down icon 1.36%
$186.88
price down icon 2.22%
Cap:     |  Volume (24h):