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Agios Pharmaceuticals Inc stock is traded at $28.16, with a volume of 1.17M. It is up +0.57% in the last 24 hours and down -17.64% over the past month. Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.
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Previous Close:
$28.00
Open:
$28
24h Volume:
1.17M
Relative Volume:
1.13
Market Cap:
$1.67B
Revenue:
$66.05M
Net Income/Loss:
$-422.60M
P/E Ratio:
-3.8836
EPS:
-7.251
Net Cash Flow:
$-384.73M
1W Performance:
+11.22%
1M Performance:
-17.64%
6M Performance:
-34.88%
1Y Performance:
-8.99%
1-Day Range:
Value
$27.25
$28.40
1-Week Range:
Value
$24.29
$28.82
52-Week Range:
Value
$22.24
$46.00

Agios Pharmaceuticals Inc Stock (AGIO) Company Profile

Name
Name
Agios Pharmaceuticals Inc
Name
Phone
617-649-8600
Name
Address
88 SIDNEY STREET, CAMBRIDGE, MA
Name
Employee
540
Name
Twitter
@AgiosPharma
Name
Next Earnings Date
2026-04-29
Name
Latest SEC Filings
Name
AGIO's Discussions on Twitter

Compare AGIO vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
AGIO icon
AGIO
Agios Pharmaceuticals Inc
28.16 1.67B 66.05M -422.60M -384.73M -7.251
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
423.92 107.83B 12.07B 3.95B 3.19B 15.33
REGN icon
REGN
Regeneron Pharmaceuticals Inc
701.42 73.54B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
783.50 48.72B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
296.11 39.51B 3.71B 313.75M 465.38M 2.2571
ONC icon
ONC
Beone Medicines Ltd Adr
293.86 32.66B 5.36B 287.73M 924.18M 2.5229

Agios Pharmaceuticals Inc Stock (AGIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-20-26 Reiterated H.C. Wainwright Buy
Nov-24-25 Initiated Truist Buy
Nov-20-25 Upgrade Leerink Partners Market Perform → Outperform
Nov-19-25 Downgrade RBC Capital Mkts Outperform → Sector Perform
Feb-24-25 Initiated H.C. Wainwright Buy
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-10-24 Resumed Raymond James Outperform
Sep-27-24 Downgrade Leerink Partners Outperform → Market Perform
Feb-08-24 Initiated Cantor Fitzgerald Overweight
Feb-03-23 Initiated Piper Sandler Overweight
Nov-17-22 Upgrade Goldman Sell → Neutral
Jul-27-22 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-03-21 Initiated BofA Securities Buy
Jul-30-21 Downgrade Goldman Neutral → Sell
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-10-21 Initiated H.C. Wainwright Buy
Mar-01-21 Downgrade JP Morgan Overweight → Neutral
Mar-01-21 Upgrade SVB Leerink Mkt Perform → Outperform
Feb-26-21 Downgrade SVB Leerink Outperform → Mkt Perform
Oct-22-20 Upgrade Barclays Equal Weight → Overweight
Mar-04-20 Initiated Barclays Equal Weight
Nov-26-19 Initiated Cantor Fitzgerald Overweight
Sep-23-19 Upgrade Guggenheim Neutral → Buy
May-23-19 Resumed Goldman Neutral
Feb-15-19 Upgrade SVB Leerink Mkt Perform → Outperform
Sep-25-18 Initiated Leerink Partners Mkt Perform
May-23-18 Initiated Citigroup Buy
Apr-11-18 Reiterated Credit Suisse Outperform
Feb-15-18 Reiterated Needham Buy
Feb-15-18 Reiterated SunTrust Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-10-17 Reiterated Needham Buy
Aug-08-17 Reiterated SunTrust Buy
Aug-02-17 Upgrade Leerink Partners Mkt Perform → Outperform
Jun-26-17 Downgrade Janney Buy → Neutral
Jan-17-17 Upgrade Oppenheimer Perform → Outperform
Oct-24-16 Initiated Needham Buy
Jun-13-16 Upgrade JP Morgan Neutral → Overweight
May-18-16 Reiterated SunTrust Buy
View All

Agios Pharmaceuticals Inc Stock (AGIO) Latest News

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May 02, 2026

Here's Why Shares in Agios Pharmaceuticals Soared This Week (And What to Expect Next in 2026) - The Motley Fool

May 02, 2026
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May 01, 2026

RBC Capital Sticks to Its Hold Rating for Agios Pharma (AGIO) - The Globe and Mail

May 01, 2026
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May 01, 2026

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Q1 2026 Earnings Call Transcript - Insider Monkey

May 01, 2026
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May 01, 2026

Agios Pharmaceuticals Hits Day High with 13.1% Surge in Stock Price - Markets Mojo

May 01, 2026
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Apr 30, 2026

Agios Pharmaceuticals Reports 20.7 Million Dollars in Q1 Revenue - HarianBasis.co

Apr 30, 2026
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Apr 30, 2026

AGIO Beats on Q1 Earnings & Sales, Stock Up 13% on New Drug Momentum - Yahoo Finance

Apr 30, 2026
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Apr 30, 2026

Agios (AGIO) Q1 2026 Earnings Call Transcript - AOL.com

Apr 30, 2026
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Apr 30, 2026

AGIO Maintained by Truist Securities -- Price Target Lowered to $36 - GuruFocus

Apr 30, 2026
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Apr 30, 2026

Truist Financial Issues Pessimistic Forecast for Agios Pharmaceuticals (NASDAQ:AGIO) Stock Price - MarketBeat

Apr 30, 2026
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Apr 30, 2026

Agios Pharmaceuticals, Inc. Q1 2026 Earnings Call Summary - Yahoo Finance

Apr 30, 2026
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Apr 30, 2026

(AGIO) Price Dynamics and Execution-Aware Positioning - Stock Traders Daily

Apr 30, 2026
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Apr 30, 2026

Agios Pharmaceuticals Inc (AGIO) Q1 2026 Earnings Call Highlights: Robust Revenue Growth and Strategic Advances - GuruFocus

Apr 30, 2026
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Apr 30, 2026

Apellis Pharmaceuticals, Centessa Pharmaceuticals, Agios Pharmaceuticals and other big stocks moving higher on Tuesday - MSN

Apr 30, 2026
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Apr 29, 2026

AGIO SEC FilingsAgios Pharmaceuticals Inc 10-K, 10-Q, 8-K Forms - Stock Titan

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals, Inc. 2026 Q1ResultsEarnings Call Presentation (NASDAQ:AGIO) 2026-04-29 - Seeking Alpha

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals Q1 2026 Earnings Call Transcript - MarketBeat

Apr 29, 2026
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Apr 29, 2026

Why Agios Pharmaceuticals Stock Zoomed to a 13% Gain on Wednesday - Yahoo Finance

Apr 29, 2026
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Apr 29, 2026

Why Agios Pharmaceuticals Stock Zoomed to a 13% Gain on Wednesday - The Motley Fool

Apr 29, 2026
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Apr 29, 2026

Agios plans Q2 sNDA filing for mitapivat in sickle cell disease while citing >$10B 2030 market opportunity - MSN

Apr 29, 2026
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Apr 29, 2026

Earnings Call Summary | Agios Pharmaceuticals(AGIO.US) Q1 2026 Earnings Conference - 富途牛牛

Apr 29, 2026
pulisher
Apr 29, 2026

Vanguard Capital Management (NASDAQ: AGIO) reports 3.09M shares, 5.27% ownership - Stock Titan

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals (NASDAQ:AGIO) Releases Quarterly Earnings Results, Beats Estimates By $0.12 EPS - MarketBeat

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals Releases Q1 2026 Financial Results - AlphaStreet

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals : 2026 Proxy Statement (a7ac5c) - marketscreener.com

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals Q1 2026 Financial Results: Net Loss, Revenue, and Key Financial Statements - Minichart

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals (NASDAQ:AGIO) Shares Gap Up on Earnings Beat - MarketBeat

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals Q1 Earnings Call Highlights - MarketBeat

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals Inc reports results for the quarter ended March 31Earnings Summary - TradingView

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals reports $20.7M revenue, $(1.69) EPS on 10-Q - TradingView

Apr 29, 2026
pulisher
Apr 29, 2026

Agios Pharmaceuticals (NASDAQ: AGIO) grows Q1 2026 sales while funding deep rare-disease pipeline - Stock Titan

Apr 29, 2026
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Apr 29, 2026

Earnings call transcript: Agios Q1 2026 earnings soar past expectations By Investing.com - Investing.com Canada

Apr 29, 2026
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Apr 29, 2026

Agios Reports Strong Q1 Revenue Growth and Strategic Advances - GuruFocus

Apr 29, 2026
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Apr 29, 2026

Q1 2026 Agios Pharmaceuticals Inc Earnings Call Transcript - GuruFocus

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals (AGIO) Reports Q1 Loss, Tops Revenue Estimates - Yahoo Finance

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals (NASDAQ:AGIO) Q1 2026 Earnings Beat Drives Stock Rally - ChartMill

Apr 29, 2026
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Apr 29, 2026

Earnings Flash (AGIO) Agios Pharmaceuticals Posts Q1 Net Loss $1.69 a Share, vs. FactSet Est of $1.80 Loss - marketscreener.com

Apr 29, 2026
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Apr 29, 2026

Earnings Flash (AGIO) Agios Pharmaceuticals, Inc. Reports Q1 Revenue $20.7M, vs. FactSet Est of $13.3M - marketscreener.com

Apr 29, 2026
pulisher
Apr 29, 2026

Agios Reports First Quarter 2026 Financial Results and Provides Business Update - The Manila Times

Apr 29, 2026
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Apr 29, 2026

Agios Pharmaceuticals: Q1 Earnings Snapshot - marketscreener.com

Apr 29, 2026
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Apr 29, 2026

Agios (NASDAQ: AGIO) doubles mitapivat revenue and funds 2026 pipeline catalysts - Stock Titan

Apr 29, 2026
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Apr 29, 2026

New thalassemia drug writes 242 U.S. scripts as Agios plans sickle cell filing - Stock Titan

Apr 29, 2026
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Apr 29, 2026

MSN Money - MSN

Apr 29, 2026
pulisher
Apr 28, 2026

Agios Pharmaceuticals Q1 2026 earnings preview - MSN

Apr 28, 2026
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Apr 27, 2026

Q3 2025 Agios Pharmaceuticals Inc Earnings Call Transcript - GuruFocus

Apr 27, 2026
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Apr 26, 2026

Agios falls as Leerink cites deaths linked to lead asset Pyrukynd - MSN

Apr 26, 2026
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Apr 26, 2026

BofA Reaffirms Buy Rating for Agios Pharmaceuticals (AGIO) - Insider Monkey

Apr 26, 2026
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Apr 25, 2026

10 Oversold Small Cap Stocks to Buy Now - Insider Monkey

Apr 25, 2026
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Apr 25, 2026

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Receives Consensus Rating of "Hold" from Analysts - MarketBeat

Apr 25, 2026
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Apr 24, 2026

Agios (AGIO) Q2 2025 Earnings Call Transcript - AOL.com

Apr 24, 2026
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Apr 24, 2026

[ARS] AGIOS PHARMACEUTICALS, INC. SEC Filing - Stock Titan

Apr 24, 2026
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Apr 24, 2026

Agios Pharmaceuticals (NASDAQ: AGIO) outlines 2026 virtual meeting, director elections and plan amendment - Stock Titan

Apr 24, 2026

Agios Pharmaceuticals Inc Stock (AGIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Agios Pharmaceuticals Inc Stock (AGIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Burns James William
Chief Legal Officer
Apr 02 '26
Sale
34.71
3,280
113,849
49,306
Gheuens Sarah
Chief Medical Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
83,217
Gheuens Sarah
Chief Medical Officer
Apr 02 '26
Sale
34.71
2,940
102,047
80,277
Jones Cecilia
Chief Financial Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
58,139
Jones Cecilia
Chief Financial Officer
Apr 02 '26
Sale
34.71
3,141
109,024
54,998
Milanova Tsveta
Chief Commercial Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
50,091
Milanova Tsveta
Chief Commercial Officer
Apr 02 '26
Sale
34.71
3,262
113,224
46,829
Viswanadhan Krishnan
Chief Corp Dev & Strategy
Apr 02 '26
Option Exercise
0.00
8,100
0
13,241
Viswanadhan Krishnan
Chief Corp Dev & Strategy
Apr 02 '26
Sale
34.71
2,959
102,707
10,282
Goff Brian
Chief Executive Officer
Apr 02 '26
Option Exercise
0.00
39,028
0
191,104
$27.83
price down icon 2.45%
$49.47
price down icon 1.24%
$97.54
price down icon 5.71%
$133.26
price down icon 2.25%
$139.48
price down icon 3.22%
ONC ONC
$293.86
price down icon 0.48%
Cap:     |  Volume (24h):