28.50
price up icon2.78%   0.77
after-market After Hours: 28.50
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Agios Pharmaceuticals Inc stock is traded at $28.50, with a volume of 678.36K. It is up +2.78% in the last 24 hours and up +5.28% over the past month. Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.
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Previous Close:
$27.73
Open:
$27.78
24h Volume:
678.36K
Relative Volume:
0.66
Market Cap:
$1.69B
Revenue:
$66.05M
Net Income/Loss:
$-422.60M
P/E Ratio:
-3.9305
EPS:
-7.251
Net Cash Flow:
$-384.73M
1W Performance:
-0.94%
1M Performance:
+5.28%
6M Performance:
+16.00%
1Y Performance:
-5.54%
1-Day Range:
Value
$27.64
$28.85
1-Week Range:
Value
$27.45
$29.18
52-Week Range:
Value
$22.24
$46.00

Agios Pharmaceuticals Inc Stock (AGIO) Company Profile

Name
Name
Agios Pharmaceuticals Inc
Name
Phone
617-649-8600
Name
Address
88 SIDNEY STREET, CAMBRIDGE, MA
Name
Employee
540
Name
Twitter
@AgiosPharma
Name
Next Earnings Date
2026-04-29
Name
Latest SEC Filings
Name
AGIO's Discussions on Twitter

Compare AGIO vs VRTX, REGN, ARGX, ALNY, ONC

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
AGIO icon
AGIO
Agios Pharmaceuticals Inc
28.50 1.68B 66.05M -422.60M -384.73M -7.251
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
430.44 110.81B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
649.76 66.02B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
804.25 48.27B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
298.48 38.22B 4.29B 577.22M 641.34M 4.2086
ONC icon
ONC
Beone Medicines Ltd Adr
308.74 30.41B 5.76B 514.49M 1.10B 4.4813

Agios Pharmaceuticals Inc Stock (AGIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-20-26 Reiterated H.C. Wainwright Buy
Nov-24-25 Initiated Truist Buy
Nov-20-25 Upgrade Leerink Partners Market Perform → Outperform
Nov-19-25 Downgrade RBC Capital Mkts Outperform → Sector Perform
Feb-24-25 Initiated H.C. Wainwright Buy
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-10-24 Resumed Raymond James Outperform
Sep-27-24 Downgrade Leerink Partners Outperform → Market Perform
Feb-08-24 Initiated Cantor Fitzgerald Overweight
Feb-03-23 Initiated Piper Sandler Overweight
Nov-17-22 Upgrade Goldman Sell → Neutral
Jul-27-22 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-03-21 Initiated BofA Securities Buy
Jul-30-21 Downgrade Goldman Neutral → Sell
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-10-21 Initiated H.C. Wainwright Buy
Mar-01-21 Downgrade JP Morgan Overweight → Neutral
Mar-01-21 Upgrade SVB Leerink Mkt Perform → Outperform
Feb-26-21 Downgrade SVB Leerink Outperform → Mkt Perform
Oct-22-20 Upgrade Barclays Equal Weight → Overweight
Mar-04-20 Initiated Barclays Equal Weight
Nov-26-19 Initiated Cantor Fitzgerald Overweight
Sep-23-19 Upgrade Guggenheim Neutral → Buy
May-23-19 Resumed Goldman Neutral
Feb-15-19 Upgrade SVB Leerink Mkt Perform → Outperform
Sep-25-18 Initiated Leerink Partners Mkt Perform
May-23-18 Initiated Citigroup Buy
Apr-11-18 Reiterated Credit Suisse Outperform
Feb-15-18 Reiterated Needham Buy
Feb-15-18 Reiterated SunTrust Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-10-17 Reiterated Needham Buy
Aug-08-17 Reiterated SunTrust Buy
Aug-02-17 Upgrade Leerink Partners Mkt Perform → Outperform
Jun-26-17 Downgrade Janney Buy → Neutral
Jan-17-17 Upgrade Oppenheimer Perform → Outperform
Oct-24-16 Initiated Needham Buy
Jun-13-16 Upgrade JP Morgan Neutral → Overweight
May-18-16 Reiterated SunTrust Buy
View All

Agios Pharmaceuticals Inc Stock (AGIO) Latest News

pulisher
May 19, 2026

Agios Pharmaceuticals Touts Strong AQVESME Launch as Sickle Cell Filing Advances - Yahoo Finance

May 19, 2026
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May 19, 2026

Agios Pharmaceuticals Inc at RBC Capital Markets Global Healthcare Conference Transcript - GuruFocus

May 19, 2026
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May 17, 2026

AGIO beats on Q1 earnings & sales, stock up 13% on new drug momentum - MSN

May 17, 2026
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May 17, 2026

Why is Agios Pharmaceuticals stock surging Tuesday afternoon? - MSN

May 17, 2026
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May 17, 2026

Agios plans Q2 sNDA filing for mitapivat in sickle cell disease while citing >$10B 2030 market opportunity - MSN

May 17, 2026
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May 16, 2026

How Investors Are Reacting To Agios Pharmaceuticals (AGIO) FDA Bid For Mitapivat In Sickle Cell Disease - Sahm

May 16, 2026
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May 15, 2026

Armistice Capital (NASDAQ: AGIO) holds 2.716M shares, 4.57% stake - Stock Titan

May 15, 2026
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May 15, 2026

Assessing Agios Pharmaceuticals (AGIO) Valuation After Recent Share Price Volatility - Yahoo Finance

May 15, 2026
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May 15, 2026

How Agios’ Mitapivat sNDA And New SCD Trial Design At Agios Pharmaceuticals (AGIO) Has Changed Its Investment Story - Yahoo Finance

May 15, 2026
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May 14, 2026

Developer seeking FDA’s accelerated approval for mitapivat for SCD - Sickle Cell Disease News

May 14, 2026
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May 14, 2026

TradingKey - TradingKey

May 14, 2026
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May 13, 2026

Agios sNDA And EHA Plenary Put Mitapivat At Center Of Valuation - Yahoo Finance

May 13, 2026
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May 13, 2026

Agios Seeks FDA Nod to Expand Mitapivat Label in Sickle Cell Disease - The Globe and Mail

May 13, 2026
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May 12, 2026

Agios Pharmaceuticals (AGIO) Showcases Promising Mitapivat Data at EHA 2026 - GuruFocus

May 12, 2026
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May 12, 2026

Agios submits application for mitapivat in sickle cell disease - Investing.com UK

May 12, 2026
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May 12, 2026

Agios presents mitapivat data at European hematology congress By Investing.com - Investing.com Australia

May 12, 2026
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May 12, 2026

Agios submits application for mitapivat in sickle cell disease By Investing.com - Investing.com Australia

May 12, 2026
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May 12, 2026

Agios presents mitapivat data at European hematology congress - Investing.com

May 12, 2026
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May 12, 2026

Agios Pharmaceuticals to Present RISE UP Phase 3 Trial Results of Mitapivat in Sickle Cell Disease at EHA 2026 Plenary Session - Quiver Quantitative

May 12, 2026
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May 12, 2026

Agios Submits sNDA to FDA for U.S. Accelerated Approval of Mitapivat in Sickle Cell Disease - The Manila Times

May 12, 2026
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May 12, 2026

Agios to Present New Data at EHA 2026 Reinforcing the Significant Therapeutic Impact of Mitapivat Across Multiple Rare Hemolytic Anemias - The Manila Times

May 12, 2026
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May 12, 2026

New pill for sickle cell moves to FDA review, aims to cut transfusions - Stock Titan

May 12, 2026
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May 12, 2026

Oral drug lifts hemoglobin in sickle cell and thalassemia trial - Stock Titan

May 12, 2026
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May 11, 2026

Price-Driven Insight from (AGIO) for Rule-Based Strategy - Stock Traders Daily

May 11, 2026
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May 11, 2026

47,414 Shares in Agios Pharmaceuticals, Inc. $AGIO Acquired by State of New Jersey Common Pension Fund D - MarketBeat

May 11, 2026
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May 09, 2026

Number of shareholders of Agios Pharmaceuticals, Inc. – TRADEGATE:8AP - TradingView

May 09, 2026
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May 06, 2026

Lynx1 (AGIO) discloses 5.1% stake — 3.01M shares reported - Stock Titan

May 06, 2026
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May 04, 2026

Need To Know: Analysts Are Much More Bullish On Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Revenues - 富途牛牛

May 04, 2026
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May 04, 2026

Agios Pharmaceuticals, Inc. $AGIO Shares Sold by Pictet Asset Management Holding SA - MarketBeat

May 04, 2026
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May 03, 2026

Agios Pharmaceuticals Stock Rises 11.2% on Strong Q1 2026 Aqvesme Launch and Pipeline Progress - IndexBox

May 03, 2026
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May 03, 2026

Agios Pharmaceuticals (AGIO) Is Up 11.2% After Rare Disease Launch And FDA Acceleration NewsHas The Bull Case Changed? - Sahm

May 03, 2026
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May 02, 2026

Here's Why Shares in Agios Pharmaceuticals Soared This Week (And What to Expect Next in 2026) - Yahoo Finance

May 02, 2026
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May 01, 2026

RBC Capital Sticks to Its Hold Rating for Agios Pharma (AGIO) - The Globe and Mail

May 01, 2026
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May 01, 2026

MSN Money - MSN

May 01, 2026
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May 01, 2026

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Q1 2026 Earnings Call Transcript - Insider Monkey

May 01, 2026
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May 01, 2026

Agios Pharmaceuticals Hits Day High with 13.1% Surge in Stock Price - Markets Mojo

May 01, 2026
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Apr 30, 2026

Agios Pharmaceuticals Reports 20.7 Million Dollars in Q1 Revenue - HarianBasis.co

Apr 30, 2026
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Apr 30, 2026

AGIO Beats on Q1 Earnings & Sales, Stock Up 13% on New Drug Momentum - The Globe and Mail

Apr 30, 2026
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Apr 30, 2026

Agios (AGIO) Q1 2026 Earnings Call Transcript - AOL.com

Apr 30, 2026
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Apr 30, 2026

AGIO Maintained by Truist Securities -- Price Target Lowered to $36 - GuruFocus

Apr 30, 2026
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Apr 30, 2026

Why Agios Pharmaceuticals Stock Zoomed to a 13% Gain on Wednesday - AOL.com

Apr 30, 2026
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Apr 30, 2026

Truist Financial Issues Pessimistic Forecast for Agios Pharmaceuticals (NASDAQ:AGIO) Stock Price - MarketBeat

Apr 30, 2026
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Apr 30, 2026

Agios Pharmaceuticals, Inc. Q1 2026 Earnings Call Summary - Yahoo Finance

Apr 30, 2026
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Apr 30, 2026

(AGIO) Price Dynamics and Execution-Aware Positioning - Stock Traders Daily

Apr 30, 2026
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Apr 30, 2026

Agios Pharmaceuticals Inc (AGIO) Q1 2026 Earnings Call Highlights: Robust Revenue Growth and Strategic Advances - GuruFocus

Apr 30, 2026

Agios Pharmaceuticals Inc Stock (AGIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Agios Pharmaceuticals Inc Stock (AGIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Burns James William
Chief Legal Officer
Apr 02 '26
Sale
34.71
3,280
113,849
49,306
Gheuens Sarah
Chief Medical Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
83,217
Gheuens Sarah
Chief Medical Officer
Apr 02 '26
Sale
34.71
2,940
102,047
80,277
Jones Cecilia
Chief Financial Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
58,139
Jones Cecilia
Chief Financial Officer
Apr 02 '26
Sale
34.71
3,141
109,024
54,998
Milanova Tsveta
Chief Commercial Officer
Apr 02 '26
Option Exercise
0.00
8,500
0
50,091
Milanova Tsveta
Chief Commercial Officer
Apr 02 '26
Sale
34.71
3,262
113,224
46,829
Viswanadhan Krishnan
Chief Corp Dev & Strategy
Apr 02 '26
Option Exercise
0.00
8,100
0
13,241
Viswanadhan Krishnan
Chief Corp Dev & Strategy
Apr 02 '26
Sale
34.71
2,959
102,707
10,282
Goff Brian
Chief Executive Officer
Apr 02 '26
Option Exercise
0.00
39,028
0
191,104
$90.36
price up icon 2.93%
$32.41
price up icon 14.89%
$107.91
price up icon 0.47%
$53.06
price up icon 1.24%
$150.33
price up icon 2.06%
ONC ONC
$308.74
price up icon 3.95%
Cap:     |  Volume (24h):