29.40
price down icon3.35%   -1.02
after-market After Hours: 29.14 -0.26 -0.88%
loading
Agios Pharmaceuticals Inc stock is traded at $29.40, with a volume of 1.43M. It is down -3.35% in the last 24 hours and up +4.81% over the past month. Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.
See More
Previous Close:
$30.42
Open:
$29.09
24h Volume:
1.43M
Relative Volume:
1.39
Market Cap:
$1.75B
Revenue:
$66.05M
Net Income/Loss:
$-422.60M
P/E Ratio:
-4.0546
EPS:
-7.251
Net Cash Flow:
$-384.73M
1W Performance:
+4.48%
1M Performance:
+4.81%
6M Performance:
+0.68%
1Y Performance:
-7.66%
1-Day Range:
Value
$28.50
$30.28
1-Week Range:
Value
$27.51
$30.53
52-Week Range:
Value
$22.24
$46.00

Agios Pharmaceuticals Inc Stock (AGIO) Company Profile

Name
Name
Agios Pharmaceuticals Inc
Name
Phone
617-649-8600
Name
Address
88 SIDNEY STREET, CAMBRIDGE, MA
Name
Employee
540
Name
Twitter
@AgiosPharma
Name
Next Earnings Date
2026-04-29
Name
Latest SEC Filings
Name
AGIO's Discussions on Twitter

Compare AGIO vs VRTX, REGN, ARGX, ALNY, RVMD

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
AGIO icon
AGIO
Agios Pharmaceuticals Inc
29.40 1.81B 66.05M -422.60M -384.73M -7.251
VRTX icon
VRTX
Vertex Pharmaceuticals Inc
447.54 113.70B 12.34B 4.34B 3.71B 16.87
REGN icon
REGN
Regeneron Pharmaceuticals Inc
614.78 65.16B 14.92B 4.42B 3.79B 41.04
ARGX icon
ARGX
Argen X Se Adr
835.99 52.14B 4.16B 1.29B 734.26M 19.58
ALNY icon
ALNY
Alnylam Pharmaceuticals Inc
301.98 40.73B 4.29B 577.22M 641.34M 4.2086
RVMD icon
RVMD
Revolution Medicines Inc
157.48 32.87B 742.00K -1.37B -1.07B -7.0731

Agios Pharmaceuticals Inc Stock (AGIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Apr-20-26 Reiterated H.C. Wainwright Buy
Nov-24-25 Initiated Truist Buy
Nov-20-25 Upgrade Leerink Partners Market Perform → Outperform
Nov-19-25 Downgrade RBC Capital Mkts Outperform → Sector Perform
Feb-24-25 Initiated H.C. Wainwright Buy
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-10-24 Resumed Raymond James Outperform
Sep-27-24 Downgrade Leerink Partners Outperform → Market Perform
Feb-08-24 Initiated Cantor Fitzgerald Overweight
Feb-03-23 Initiated Piper Sandler Overweight
Nov-17-22 Upgrade Goldman Sell → Neutral
Jul-27-22 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-03-21 Initiated BofA Securities Buy
Jul-30-21 Downgrade Goldman Neutral → Sell
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-10-21 Initiated H.C. Wainwright Buy
Mar-01-21 Downgrade JP Morgan Overweight → Neutral
Mar-01-21 Upgrade SVB Leerink Mkt Perform → Outperform
Feb-26-21 Downgrade SVB Leerink Outperform → Mkt Perform
Oct-22-20 Upgrade Barclays Equal Weight → Overweight
Mar-04-20 Initiated Barclays Equal Weight
Nov-26-19 Initiated Cantor Fitzgerald Overweight
Sep-23-19 Upgrade Guggenheim Neutral → Buy
May-23-19 Resumed Goldman Neutral
Feb-15-19 Upgrade SVB Leerink Mkt Perform → Outperform
Sep-25-18 Initiated Leerink Partners Mkt Perform
May-23-18 Initiated Citigroup Buy
Apr-11-18 Reiterated Credit Suisse Outperform
Feb-15-18 Reiterated Needham Buy
Feb-15-18 Reiterated SunTrust Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-10-17 Reiterated Needham Buy
Aug-08-17 Reiterated SunTrust Buy
Aug-02-17 Upgrade Leerink Partners Mkt Perform → Outperform
Jun-26-17 Downgrade Janney Buy → Neutral
Jan-17-17 Upgrade Oppenheimer Perform → Outperform
Oct-24-16 Initiated Needham Buy
Jun-13-16 Upgrade JP Morgan Neutral → Overweight
May-18-16 Reiterated SunTrust Buy
View All

Agios Pharmaceuticals Inc Stock (AGIO) Latest News

pulisher
04:11 AM

Agios: 'Sell' On Tebapivat Setback LR-MDS And Competitive PK Activator Drug Class - Seeking Alpha

04:11 AM
pulisher
03:20 AM

Agios Pharmaceuticals, Inc. Stock 12‑Month Price Target Cut to $40.88, Implies 34% Upside - TradingView

03:20 AM
pulisher
03:08 AM

AGIO Maintained by B of A Securities -- Price Target Lowered to $40 - GuruFocus

03:08 AM
pulisher
11:30 AM

Why Is Agios Pharmaceuticals (AGIO) Up 8.6% Since Last Earnings Report? - Yahoo Finance UK

11:30 AM
pulisher
10:26 AM

Agios slides after discontinuing development of tebapivat in myelodysplastic syndromes (AGIO) - Yahoo Finance

10:26 AM
pulisher
09:08 AM

Agios Pharmaceuticals (AGIO) Discontinues Myelodysplastic Syndro - GuruFocus

09:08 AM
pulisher
08:36 AM

Agios provides update on phase 2b trial of tebapivat in lower-risk myelodysplastic syndromes - marketscreener.com

08:36 AM
pulisher
07:53 AM

Agios to drop myelodysplastic syndromes drug (AGIO:NASDAQ) - Seeking Alpha

07:53 AM
pulisher
07:49 AM

Agios Pharmaceuticals (AGIO) Halts Tebapivat Development for Low - GuruFocus

07:49 AM
pulisher
07:24 AM

Agios Pharmaceuticals stock tumbles on trial setback By Investing.com - Investing.com Canada

07:24 AM
pulisher
07:21 AM

Agios scraps blood cancer drug program after study miss - marketscreener.com

07:21 AM
pulisher
07:13 AM

Agios halts tebapivat development for blood disorder - Investing.com

07:13 AM
pulisher
07:13 AM

Agios halts tebapivat development for blood disorder By Investing.com - Investing.com Canada

07:13 AM
pulisher
07:07 AM

Agios scraps blood disorder drug program after study miss - marketscreener.com

07:07 AM
pulisher
07:00 AM

Agios to stop tebapivat in LR-MDS, plans sickle cell data in 2H 2026 - Stock Titan

07:00 AM
pulisher
May 28, 2026

Here's Why Agios Pharmaceuticals Crashed 23% Today - AOL.com

May 28, 2026
pulisher
May 25, 2026

AGIO's Pyrukynd Gets Approval for Thalassemia in Europe - The Globe and Mail

May 25, 2026
pulisher
May 25, 2026

Agios Pharmaceuticals Gains EU Approval for PYRUKYND in Adult Thalassaemia - World Business Outlook

May 25, 2026
pulisher
May 22, 2026

Avanzanite Bioscience’s Partner Agios Announces PYRUKYND® (mitapivat) Approval in the European Union for Adults with Thalassaemia - afp.com

May 22, 2026
pulisher
May 22, 2026

Agios, Partner von Avanzanite Bioscience, gibt die Zulassung von PYRUKYND® (Mitapivat) in der Europäischen Union für Erwachsene mit Thalassämie bekannt - The Joplin Globe

May 22, 2026
pulisher
May 22, 2026

Agios Pharmaceuticals (AGIO) Secures EU Approval for PYRUKYND - GuruFocus

May 22, 2026
pulisher
May 22, 2026

EU approves mitapivat for thalassaemia treatment in adults - Investing.com UK

May 22, 2026
pulisher
May 22, 2026

EU approves mitapivat for thalassaemia treatment in adults By Investing.com - Investing.com Nigeria

May 22, 2026
pulisher
May 22, 2026

Avanzanite Bioscience's partner Agios announces Pyrukynd® (mitapivat) approval in EU - marketscreener.com

May 22, 2026
pulisher
May 22, 2026

Agios Gets EU Approval for Pyrukynd in Thalassemia - Moomoo

May 22, 2026
pulisher
May 22, 2026

New oral thalassemia drug PYRUKYND approved for adults in EU - Stock Titan

May 22, 2026
pulisher
May 22, 2026

Agios' Pyrukynd® (mitapivat) approved in the European Union for adults with thalassemia - marketscreener.com

May 22, 2026
pulisher
May 22, 2026

Agios’ PYRUKYND® (mitapivat) Approved in the European Union for Adults with Thalassemia - The Manila Times

May 22, 2026
pulisher
May 22, 2026

Agios Pharmaceuticals Receives EU Approval for PYRUKYND® as First Medicine for Thalassemia Treatment in Adults - Quiver Quantitative

May 22, 2026
pulisher
May 22, 2026

EU clears sole approved drug for adults with alpha- or beta-thalassemia - Stock Titan

May 22, 2026
pulisher
May 22, 2026

(AGIO) Volatility Zones as Tactical Triggers - Stock Traders Daily

May 22, 2026
pulisher
May 19, 2026

Agios Pharmaceuticals touts strong AQVESME launch as sickle cell filing advances - MSN

May 19, 2026
pulisher
May 19, 2026

Agios Pharmaceuticals Touts Strong AQVESME Launch as Sickle Cell Filing Advances - TradingView

May 19, 2026
pulisher
May 19, 2026

Agios Pharmaceuticals Inc at RBC Capital Markets Global Healthcare Conference Transcript - GuruFocus

May 19, 2026
pulisher
May 17, 2026

AGIO beats on Q1 earnings & sales, stock up 13% on new drug momentum - MSN

May 17, 2026
pulisher
May 17, 2026

Why is Agios Pharmaceuticals stock surging Tuesday afternoon? - MSN

May 17, 2026
pulisher
May 17, 2026

Agios plans Q2 sNDA filing for mitapivat in sickle cell disease while citing >$10B 2030 market opportunity - MSN

May 17, 2026
pulisher
May 16, 2026

How Investors Are Reacting To Agios Pharmaceuticals (AGIO) FDA Bid For Mitapivat In Sickle Cell Disease - Sahm

May 16, 2026
pulisher
May 15, 2026

Armistice Capital (NASDAQ: AGIO) holds 2.716M shares, 4.57% stake - Stock Titan

May 15, 2026
pulisher
May 15, 2026

Assessing Agios Pharmaceuticals (AGIO) Valuation After Recent Share Price Volatility - Yahoo Finance

May 15, 2026
pulisher
May 15, 2026

How Agios’ Mitapivat sNDA And New SCD Trial Design At Agios Pharmaceuticals (AGIO) Has Changed Its Investment Story - Yahoo Finance

May 15, 2026
pulisher
May 14, 2026

Developer seeking FDA’s accelerated approval for mitapivat for SCD - Sickle Cell Disease News

May 14, 2026
pulisher
May 14, 2026

TradingKey - TradingKey

May 14, 2026
pulisher
May 13, 2026

Agios sNDA And EHA Plenary Put Mitapivat At Center Of Valuation - Yahoo Finance

May 13, 2026
pulisher
May 13, 2026

Agios Seeks FDA Nod to Expand Mitapivat Label in Sickle Cell Disease - The Globe and Mail

May 13, 2026
pulisher
May 13, 2026

BofA Securities Maintains Agios Pharmaceuticals(AGIO.US) With Buy Rating, Maintains Target Price $41 - Moomoo

May 13, 2026
pulisher
May 12, 2026

Agios Pharmaceuticals (AGIO) Showcases Promising Mitapivat Data at EHA 2026 - GuruFocus

May 12, 2026
pulisher
May 12, 2026

Agios submits application for mitapivat in sickle cell disease - Investing.com UK

May 12, 2026
pulisher
May 12, 2026

Agios presents mitapivat data at European hematology congress By Investing.com - Investing.com Australia

May 12, 2026
pulisher
May 12, 2026

Agios submits application for mitapivat in sickle cell disease By Investing.com - Investing.com Australia

May 12, 2026
pulisher
May 12, 2026

Agios presents mitapivat data at European hematology congress - Investing.com

May 12, 2026

Agios Pharmaceuticals Inc Stock (AGIO) Financials Data

Revenue

loading

Net Income

loading

Cash Flow

loading

EPS

loading
$29.99
price up icon 0.37%
$106.91
price down icon 1.35%
$95.95
price up icon 2.69%
$55.76
price up icon 2.35%
ONC ONC
$287.92
price down icon 0.92%
$157.48
price up icon 1.84%
Cap:     |  Volume (24h):