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Agios Pharmaceuticals Inc stock is traded at $27.27, with a volume of 1.18M. It is down -0.69% in the last 24 hours and down -37.50% over the past month. Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236, and others.
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Previous Close:
$27.46
Open:
$27.52
24h Volume:
1.18M
Relative Volume:
0.99
Market Cap:
$1.59B
Revenue:
$32.87M
Net Income/Loss:
$674.31M
P/E Ratio:
2.4005
EPS:
11.36
Net Cash Flow:
$-330.11M
1W Performance:
-1.66%
1M Performance:
-37.50%
6M Performance:
-20.96%
1Y Performance:
-28.56%
1-Day Range:
Value
$26.78
$27.66
1-Week Range:
Value
$26.78
$28.61
52-Week Range:
Value
$22.24
$46.00

Agios Pharmaceuticals Inc Stock (AGIO) Company Profile

Name
Name
Agios Pharmaceuticals Inc
Name
Phone
617-649-8600
Name
Address
88 SIDNEY STREET, CAMBRIDGE, MA
Name
Employee
488
Name
Twitter
@AgiosPharma
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
AGIO's Discussions on Twitter

Compare AGIO with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
AGIO
Agios Pharmaceuticals Inc
27.27 1.60B 32.87M 674.31M -330.11M 11.36
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
452.04 113.14B 11.74B 3.68B 3.34B 14.19
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
741.29 78.49B 14.25B 4.58B 3.88B 41.77
Biotechnology icon
ARGX
Argen X Se Adr
877.94 54.76B 3.06B 1.28B 447.35M 19.67
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
397.55 54.51B 3.21B 43.57M 221.36M 0.2405
Biotechnology icon
INSM
Insmed Inc
197.01 41.64B 447.02M -1.18B -906.14M -6.1812

Agios Pharmaceuticals Inc Stock (AGIO) Upgrades & Downgrades

Date Action Analyst Rating Change
Nov-24-25 Initiated Truist Buy
Nov-20-25 Upgrade Leerink Partners Market Perform → Outperform
Nov-19-25 Downgrade RBC Capital Mkts Outperform → Sector Perform
Feb-24-25 Initiated H.C. Wainwright Buy
Oct-16-24 Initiated Scotiabank Sector Outperform
Oct-10-24 Resumed Raymond James Outperform
Sep-27-24 Downgrade Leerink Partners Outperform → Market Perform
Feb-08-24 Initiated Cantor Fitzgerald Overweight
Feb-03-23 Initiated Piper Sandler Overweight
Nov-17-22 Upgrade Goldman Sell → Neutral
Jul-27-22 Upgrade SVB Leerink Mkt Perform → Outperform
Dec-03-21 Initiated BofA Securities Buy
Jul-30-21 Downgrade Goldman Neutral → Sell
Jul-01-21 Initiated Raymond James Mkt Perform
Jun-10-21 Initiated H.C. Wainwright Buy
Mar-01-21 Downgrade JP Morgan Overweight → Neutral
Mar-01-21 Upgrade SVB Leerink Mkt Perform → Outperform
Feb-26-21 Downgrade SVB Leerink Outperform → Mkt Perform
Oct-22-20 Upgrade Barclays Equal Weight → Overweight
Mar-04-20 Initiated Barclays Equal Weight
Nov-26-19 Initiated Cantor Fitzgerald Overweight
Sep-23-19 Upgrade Guggenheim Neutral → Buy
May-23-19 Resumed Goldman Neutral
Feb-15-19 Upgrade SVB Leerink Mkt Perform → Outperform
Sep-25-18 Initiated Leerink Partners Mkt Perform
May-23-18 Initiated Citigroup Buy
Apr-11-18 Reiterated Credit Suisse Outperform
Feb-15-18 Reiterated Needham Buy
Feb-15-18 Reiterated SunTrust Buy
Sep-15-17 Initiated RBC Capital Mkts Outperform
Aug-10-17 Reiterated Needham Buy
Aug-08-17 Reiterated SunTrust Buy
Aug-02-17 Upgrade Leerink Partners Mkt Perform → Outperform
Jun-26-17 Downgrade Janney Buy → Neutral
Jan-17-17 Upgrade Oppenheimer Perform → Outperform
Oct-24-16 Initiated Needham Buy
Jun-13-16 Upgrade JP Morgan Neutral → Overweight
May-18-16 Reiterated SunTrust Buy
View All

Agios Pharmaceuticals Inc Stock (AGIO) Latest News

pulisher
04:26 AM

Agios Pharmaceuticals, Inc. $AGIO Position Boosted by Boothbay Fund Management LLC - MarketBeat

04:26 AM
pulisher
Dec 12, 2025

Levi & Korsinsky Announces an Investigation on Behalf of Agios Pharmaceuticals, Inc. (AGIO) Shareholders Who May Have Been Affected by Fraud - ACCESS Newswire

Dec 12, 2025
pulisher
Dec 11, 2025

Is Agios Pharmaceuticals Inc 8AP a good long term investmentSell Signals and Alerts & Learn From the Strategies of Institutions - earlytimes.in

Dec 11, 2025
pulisher
Dec 11, 2025

Agios Pharmaceuticals, Inc. (AGIO) Investors with Losses are Urged to Contact Levi & Korsinsky to Discuss Their Rights - ACCESS Newswire

Dec 11, 2025
pulisher
Dec 10, 2025

Levi & Korsinsky Reminds Agios Pharmaceuticals, Inc. Investors of the Ongoing Investigation into Potential Violations of Securities LawsAGIO - ACCESS Newswire

Dec 10, 2025
pulisher
Dec 09, 2025

Agios Awaits Pyrukynd Decision in Thalassemia as FDA Misses Due Date - The Globe and Mail

Dec 09, 2025
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Dec 09, 2025

Agios Pharma stock awaits FDA decision on Pyrukynd as PDUFA date passes - Investing.com Canada

Dec 09, 2025
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Dec 09, 2025

AGIO STOCK ALERT: Levi & Korsinsky Notifies Agios Pharmaceuticals, Inc. Investors of an Ongoing Investigation - ACCESS Newswire

Dec 09, 2025
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Dec 09, 2025

Marshall Wace LLP Purchases 163,796 Shares of Agios Pharmaceuticals, Inc. $AGIO - MarketBeat

Dec 09, 2025
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Dec 08, 2025

Agios Pharmaceuticals' Supplemental NDA for Mitapivat to Treat Thalassemia Still Under FDA Review - marketscreener.com

Dec 08, 2025
pulisher
Dec 08, 2025

Agios shares slide after FDA misses decision deadline on mitapivat application - MSN

Dec 08, 2025
pulisher
Dec 08, 2025

Agios Pharmaceuticals (AGIO) Awaits FDA Decision on Mitapivat Ap - GuruFocus

Dec 08, 2025
pulisher
Dec 08, 2025

Agios Pharmaceuticals says FDA has not issued decision on Agios' sNDA for mitapivat - marketscreener.com

Dec 08, 2025
pulisher
Dec 08, 2025

FDA delays decision on Agios’ thalassemia drug application By Investing.com - Investing.com Canada

Dec 08, 2025
pulisher
Dec 08, 2025

Agios Pharma falls after FDA misses decision deadline on blood-disorder drug filing - TradingView

Dec 08, 2025
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Dec 08, 2025

Agios Pharmaceuticals Provides Update on FDA Review Status for Supplemental New Drug Application of Mitapivat for Thalassemia - Quiver Quantitative

Dec 08, 2025
pulisher
Dec 08, 2025

Agios stock falls after FDA delays decision on thalassemia drug By Investing.com - Investing.com UK

Dec 08, 2025
pulisher
Dec 08, 2025

Agios Provides Update on U.S. sNDA for Mitapivat in Thalassemia - The Manila Times

Dec 08, 2025
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Dec 08, 2025

Agios (Nasdaq: AGIO) says FDA mitapivat thalassemia sNDA still under review after Dec. 7 PDUFA goal date - Stock Titan

Dec 08, 2025
pulisher
Dec 07, 2025

(AGIO) as a Liquidity Pulse for Institutional Tactics - news.stocktradersdaily.com

Dec 07, 2025
pulisher
Dec 06, 2025

Agios Faces A Make-Or-Break Year As Key Drug Decisions Loom - Finimize

Dec 06, 2025
pulisher
Dec 05, 2025

How The Latest Trial And FDA Risk Shift The Story For Agios Pharmaceuticals - Yahoo Finance

Dec 05, 2025
pulisher
Dec 05, 2025

Bronstein, Gewirtz & Grossman, LLC (AGIO) Investigation: Bronstei - The National Law Review

Dec 05, 2025
pulisher
Dec 05, 2025

How Agios Pharmaceuticals Inc. (8AP) stock trades pre earningsMarket Movement Recap & Daily Profit Focused Stock Screening - Newser

Dec 05, 2025
pulisher
Dec 05, 2025

Will Agios Pharmaceuticals Inc. (8AP) stock hit analyst forecasts2025 Support & Resistance & Fast Gaining Stock Reports - Newser

Dec 05, 2025
pulisher
Dec 05, 2025

Why Agios Pharmaceuticals Inc. (8AP) stock stays on buy listsPortfolio Update Report & Growth Oriented Trading Recommendations - Newser

Dec 05, 2025
pulisher
Dec 05, 2025

How analysts rate Agios Pharmaceuticals Inc. stock todayPortfolio Gains Report & Daily Technical Forecast Reports - Newser

Dec 05, 2025
pulisher
Dec 04, 2025

Why Agios Pharmaceuticals Inc. (8AP) stock appears on watchlists2025 Historical Comparison & Real-Time Stock Entry Alerts - Newser

Dec 04, 2025
pulisher
Dec 04, 2025

Why Agios Pharmaceuticals (AGIO) Is Down 7.1% After Phase 3 Sickle Cell Win With Mitapivat - Sahm

Dec 04, 2025
pulisher
Dec 04, 2025

Europe Autoimmune Hemolytic Anemia Therapeutics Market to hit - openPR.com

Dec 04, 2025
pulisher
Dec 04, 2025

How cyclical is Agios Pharmaceuticals Inc. (8AP) stock compared to rivalsJuly 2025 Opening Moves & Low Risk Investment Opportunities - Newser

Dec 04, 2025
pulisher
Dec 03, 2025

Sickle Cell Disease Market is Predicted to Exhibit Remarkable Growth at a CAGR of 22.1% During the Forecast Period (2025–2034) Across 6MM, Owing to the Increasing Prevalence, Awareness, and Advancements in Gene Therapies | DelveInsight - GlobeNewswire Inc.

Dec 03, 2025
pulisher
Dec 03, 2025

Fisher Asset Management LLC Sells 81,799 Shares of Agios Pharmaceuticals, Inc. $AGIO - MarketBeat

Dec 03, 2025
pulisher
Dec 03, 2025

Is Agios Pharmaceuticals Inc. (8AP) stock a top dividend aristocrat candidateWeekly Trading Summary & Weekly Return Optimization Plans - Newser

Dec 03, 2025
pulisher
Dec 03, 2025

Published on: 2025-12-03 01:52:18 - Newser

Dec 03, 2025
pulisher
Dec 02, 2025

Prudential Financial Inc. Lowers Holdings in Agios Pharmaceuticals, Inc. $AGIO - MarketBeat

Dec 02, 2025
pulisher
Dec 02, 2025

How Agios Pharmaceuticals Inc. (8AP) stock gains from tech spending2025 Breakouts & Breakdowns & Fast Entry and Exit Trade Plans - Newser

Dec 02, 2025
pulisher
Dec 02, 2025

Agios Pharmaceuticals (AGIO) Upgraded After Mixed Sickle Cell Data and Pending Thalassemia Catalyst - MSN

Dec 02, 2025
pulisher
Dec 02, 2025

How Agios Pharmaceuticals Inc. (8AP) stock moves on employment dataMarket Risk Summary & Growth Focused Investment Plans - Newser

Dec 02, 2025
pulisher
Dec 02, 2025

Published on: 2025-12-02 00:03:25 - Newser

Dec 02, 2025
pulisher
Nov 30, 2025

Is Agios Pharmaceuticals Inc a good long term investmentPortfolio Risk Assessment & Minimal Capital Trading Tips - earlytimes.in

Nov 30, 2025
pulisher
Nov 30, 2025

Agios Pharmaceuticals (NASDAQ:AGIO) Upgraded by Citigroup to Strong-Buy Rating - MarketBeat

Nov 30, 2025
pulisher
Nov 29, 2025

How Agios Pharmaceuticals Inc. stock reacts to Fed rate cutsJuly 2025 Chart Watch & Verified Stock Trade Ideas - BỘ NỘI VỤ

Nov 29, 2025
pulisher
Nov 29, 2025

How Agios Pharmaceuticals Inc. stock valuations compare to rivals2025 Biggest Moves & Long Hold Capital Preservation Tips - BỘ NỘI VỤ

Nov 29, 2025
pulisher
Nov 29, 2025

A Look at Agios Pharmaceuticals (AGIO) Valuation Following Strong Phase 3 Sickle Cell Trial Results - Sahm

Nov 29, 2025
pulisher
Nov 29, 2025

Envestnet Asset Management Inc. Reduces Holdings in Agios Pharmaceuticals, Inc. $AGIO - MarketBeat

Nov 29, 2025
pulisher
Nov 29, 2025

Aug Intraday: How strong is Agios Pharmaceuticals Inc. stock balance sheet2025 Fundamental Recap & AI Powered Buy and Sell Recommendations - moha.gov.vn

Nov 29, 2025
pulisher
Nov 28, 2025

Agios Pharmaceuticals Inc Stock Analysis and ForecastDividend Aristocrats List & Trusted Financial Advisors at No Cost - earlytimes.in

Nov 28, 2025
pulisher
Nov 28, 2025

Intech Investment Management LLC Sells 12,496 Shares of Agios Pharmaceuticals, Inc. $AGIO - MarketBeat

Nov 28, 2025
pulisher
Nov 28, 2025

FY2026 EPS Estimates for AGIO Increased by Cantor Fitzgerald - MarketBeat

Nov 28, 2025
pulisher
Nov 27, 2025

Geode Capital Management LLC Boosts Holdings in Agios Pharmaceuticals, Inc. $AGIO - MarketBeat

Nov 27, 2025

Agios Pharmaceuticals Inc Stock (AGIO) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Agios Pharmaceuticals Inc Stock (AGIO) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Scadden David
Director
Nov 12 '25
Sale
43.84
200
8,768
17,603
Gheuens Sarah
Chief Medical Officer
Nov 11 '25
Option Exercise
25.01
2,454
61,375
64,181
Gheuens Sarah
Chief Medical Officer
Nov 11 '25
Sale
43.78
2,454
107,436
61,727
$38.39
price down icon 1.08%
$95.41
price down icon 0.72%
$31.31
price down icon 3.07%
$94.81
price down icon 1.24%
biotechnology ONC
$319.06
price down icon 0.55%
$197.01
price up icon 0.91%
Cap:     |  Volume (24h):