Denali Therapeutics Inc (DNLI)

Panoramica Notizia Cronologia dei prezzi Catena di opzioni Financials Perché DNLI Giù? Forum Previsione

Perché le azioni Denali Therapeutics Inc (DNLI) sono in ribasso?

Abbiamo notato un calo di 5.01% nelle azioni di Denali Therapeutics Inc (DNLI) durante la sessione di negoziazione di 2024-04-25. Sebbene ciò possa essere attribuito alla normale volatilità o a vari fattori interni ed esterni, tieni presente che stiamo monitorando attivamente la situazione e forniremo aggiornamenti tempestivi il prima possibile!

2024-02-16:

Denali Therapeutics Inc (DNLI) stock fell by 7.30% due to the announcement that its Phase 2 Himalaya study, aimed at treating patients with amyotrophic lateral sclerosis (ALS) using an oral brain-penetrant inhibitor, did not meet the primary endpoint.

Details of the Announcement: Denali Therapeutics, a biotechnology company, revealed that the SAR443820/DNL788 inhibitor, developed in collaboration with Sanofi, failed to meet the primary endpoint of change in ALS functional rating scale-revised (ALSFRS-R). Consequently, shares of Denali Therapeutics fell by 7.4% to $17.01 in recent trading. The stock has experienced a decline of 22% since the beginning of the year and 45% over the past 12 months.
Future Plans: Despite the setback in the ALS study, Sanofi, Denali's collaborator, intends to proceed with the K2 Phase 2 study of SAR443820/DNL788 in participants with multiple sclerosis. This indicates that while the ALS trial did not yield favorable results, there are ongoing efforts to explore the potential of the inhibitor in other therapeutic areas.